2025808:CCZ37 RS09660
gene id: 2025808:CCZ37_RS09660
uniprot id: A0A223MZD2
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

2025808:CCZ37 RS05345
gene id: 2025808:CCZ37_RS05345
uniprot id: A0A223N113
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS03710
gene id: 2025808:CCZ37_RS03710
uniprot id: A0A223MVY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

2025808:CCZ37 RS02870
gene id: 2025808:CCZ37_RS02870
uniprot id: A0A223MW75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

2025808:CCZ37 RS11520
gene id: 2025808:CCZ37_RS11520
uniprot id: A0A223N088
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2025808:CCZ37 RS03120
gene id: 2025808:CCZ37_RS03120
uniprot id: A0A223MVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2025808:CCZ37 RS09815
gene id: 2025808:CCZ37_RS09815
uniprot id: A0A223MZ63
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS11170
gene id: 2025808:CCZ37_RS11170
uniprot id: A0A223MZW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

2025808:CCZ37 RS15600
gene id: 2025808:CCZ37_RS15600
uniprot id: A0A223N3Y0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS10660
gene id: 2025808:CCZ37_RS10660
uniprot id: A0A223MZN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2025808:CCZ37 RS02020
gene id: 2025808:CCZ37_RS02020
uniprot id: A0A223MVC0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2025808:CCZ37 RS18760
gene id: 2025808:CCZ37_RS18760
uniprot id: A0A223N3W6
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

2025808:CCZ37 RS12935
gene id: 2025808:CCZ37_RS12935
uniprot id: A0A223N162
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2025808:CCZ37 RS09940
gene id: 2025808:CCZ37_RS09940
uniprot id: A0A223MZI5
names: Similarity
messages: Belongs to the UPF0325 family.

2025808:CCZ37 RS08045
gene id: 2025808:CCZ37_RS08045
uniprot id: A0A223MYA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2025808:CCZ37 RS04100
gene id: 2025808:CCZ37_RS04100
uniprot id: A0A223MW41
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2025808:CCZ37 RS02770
gene id: 2025808:CCZ37_RS02770
uniprot id: A0A223MVJ4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2025808:CCZ37 RS13465
gene id: 2025808:CCZ37_RS13465
uniprot id: A0A223N174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2025808:CCZ37 RS00215
gene id: 2025808:CCZ37_RS00215
uniprot id: A0A223MV19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

2025808:CCZ37 RS06760
gene id: 2025808:CCZ37_RS06760
uniprot id: A0A223MXR4
names: Subcellular Location Annotation
messages: Cytoplasm

2025808:CCZ37 RS02830
gene id: 2025808:CCZ37_RS02830
uniprot id: A0A223MVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2025808:CCZ37 RS03715
gene id: 2025808:CCZ37_RS03715
uniprot id: A0A223MW28
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2025808:CCZ37 RS09220
gene id: 2025808:CCZ37_RS09220
uniprot id: A0A223MYW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2025808:CCZ37 RS01255
gene id: 2025808:CCZ37_RS01255
uniprot id: A0A223MUU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2025808:CCZ37 RS12600
gene id: 2025808:CCZ37_RS12600
uniprot id: A0A223N0Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2025808:CCZ37 RS08805
gene id: 2025808:CCZ37_RS08805
uniprot id: A0A223MYP2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS00750
gene id: 2025808:CCZ37_RS00750
uniprot id: A0A223MUL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2025808:CCZ37 RS03790
gene id: 2025808:CCZ37_RS03790
uniprot id: A0A223MW04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2025808:CCZ37 RS00325
gene id: 2025808:CCZ37_RS00325
uniprot id: A0A223MUB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2025808:CCZ37 RS01975
gene id: 2025808:CCZ37_RS01975
uniprot id: A0A223MV30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

2025808:CCZ37 RS13660
gene id: 2025808:CCZ37_RS13660
uniprot id: A0A223N1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2025808:CCZ37 RS03310
gene id: 2025808:CCZ37_RS03310
uniprot id: A0A223MVW8
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2025808:CCZ37 RS07150
gene id: 2025808:CCZ37_RS07150
uniprot id: A0A223MYF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2025808:CCZ37 RS09300
gene id: 2025808:CCZ37_RS09300
uniprot id: A0A223MYZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

2025808:CCZ37 RS09235
gene id: 2025808:CCZ37_RS09235
uniprot id: A0A223MYX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2025808:CCZ37 RS00010
gene id: 2025808:CCZ37_RS00010
uniprot id: A0A223MU80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2025808:CCZ37 RS11075
gene id: 2025808:CCZ37_RS11075
uniprot id: A0A223MZV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

2025808:CCZ37 RS02515
gene id: 2025808:CCZ37_RS02515
uniprot id: A0A223MVC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2025808:CCZ37 RS01715
gene id: 2025808:CCZ37_RS01715
uniprot id: A0A223MV52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

2025808:CCZ37 RS15140
gene id: 2025808:CCZ37_RS15140
uniprot id: A0A223N2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2025808:CCZ37 RS02270
gene id: 2025808:CCZ37_RS02270
uniprot id: A0A223MV77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2025808:CCZ37 RS02460
gene id: 2025808:CCZ37_RS02460
uniprot id: A0A223MVD5
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

2025808:CCZ37 RS05165
gene id: 2025808:CCZ37_RS05165
uniprot id: A0A223MWX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

2025808:CCZ37 RS08085
gene id: 2025808:CCZ37_RS08085
uniprot id: A0A223MYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2025808:CCZ37 RS04830
gene id: 2025808:CCZ37_RS04830
uniprot id: A0A223MWI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS04660
gene id: 2025808:CCZ37_RS04660
uniprot id: A0A223MWF1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

2025808:CCZ37 RS07650
gene id: 2025808:CCZ37_RS07650
uniprot id: A0A223MY40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2025808:CCZ37 RS02955
gene id: 2025808:CCZ37_RS02955
uniprot id: A0A223MVU5
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2025808:CCZ37 RS00090
gene id: 2025808:CCZ37_RS00090
uniprot id: A0A223MUF6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2025808:CCZ37 RS03345
gene id: 2025808:CCZ37_RS03345
uniprot id: A0A223MW23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2025808:CCZ37 RS03230
gene id: 2025808:CCZ37_RS03230
uniprot id: A0A223MVP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2025808:CCZ37 RS13330
gene id: 2025808:CCZ37_RS13330
uniprot id: A0A223N0Z0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2025808:CCZ37 RS01950
gene id: 2025808:CCZ37_RS01950
uniprot id: A0A223MV18
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2025808:CCZ37 RS14665
gene id: 2025808:CCZ37_RS14665
uniprot id: A0A223N1N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

2025808:CCZ37 RS05015
gene id: 2025808:CCZ37_RS05015
uniprot id: A0A223MWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2025808:CCZ37 RS03200
gene id: 2025808:CCZ37_RS03200
uniprot id: A0A223MVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

2025808:CCZ37 RS04215
gene id: 2025808:CCZ37_RS04215
uniprot id: A0A223MWI5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

2025808:CCZ37 RS11415
gene id: 2025808:CCZ37_RS11415
uniprot id: A0A223N067
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2025808:CCZ37 RS10480
gene id: 2025808:CCZ37_RS10480
uniprot id: A0A223N004
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2025808:CCZ37 RS07820
gene id: 2025808:CCZ37_RS07820
uniprot id: A0A223MY61
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2025808:CCZ37 RS02950
gene id: 2025808:CCZ37_RS02950
uniprot id: A0A223MVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

2025808:CCZ37 RS14320
gene id: 2025808:CCZ37_RS14320
uniprot id: A0A223N1K3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2025808:CCZ37 RS09980
gene id: 2025808:CCZ37_RS09980
uniprot id: A0A223MZB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2025808:CCZ37 RS01110
gene id: 2025808:CCZ37_RS01110
uniprot id: A0A223MUS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

2025808:CCZ37 RS09455
gene id: 2025808:CCZ37_RS09455
uniprot id: A0A223MZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2025808:CCZ37 RS02210
gene id: 2025808:CCZ37_RS02210
uniprot id: A0A223MV64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2025808:CCZ37 RS04635
gene id: 2025808:CCZ37_RS04635
uniprot id: A0A223N0Y8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

2025808:CCZ37 RS00465
gene id: 2025808:CCZ37_RS00465
uniprot id: A0A223MUE3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

2025808:CCZ37 RS09905
gene id: 2025808:CCZ37_RS09905
uniprot id: A0A223MZ84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

2025808:CCZ37 RS02485
gene id: 2025808:CCZ37_RS02485
uniprot id: A0A223MVH0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2025808:CCZ37 RS10795
gene id: 2025808:CCZ37_RS10795
uniprot id: A0A223MZS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2025808:CCZ37 RS00440
gene id: 2025808:CCZ37_RS00440
uniprot id: A0A223MV48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2025808:CCZ37 RS08055
gene id: 2025808:CCZ37_RS08055
uniprot id: A0A223MYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2025808:CCZ37 RS05510
gene id: 2025808:CCZ37_RS05510
uniprot id: A0A223MX24
names: Subcellular Location Annotation
messages: Cytoplasm

2025808:CCZ37 RS03350
gene id: 2025808:CCZ37_RS03350
uniprot id: A0A223MVZ1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

2025808:CCZ37 RS10085
gene id: 2025808:CCZ37_RS10085
uniprot id: A0A223MZD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2025808:CCZ37 RS08820
gene id: 2025808:CCZ37_RS08820
uniprot id: A0A223MZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

2025808:CCZ37 RS08865
gene id: 2025808:CCZ37_RS08865
uniprot id: A0A223MYS2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

2025808:CCZ37 RS07640
gene id: 2025808:CCZ37_RS07640
uniprot id: A0A223MY21
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

2025808:CCZ37 RS12045
gene id: 2025808:CCZ37_RS12045
uniprot id: A0A223N0G9
names: Similarity
messages: Belongs to the carbamate kinase family.

2025808:CCZ37 RS06485
gene id: 2025808:CCZ37_RS06485
uniprot id: A0A223MXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

2025808:CCZ37 RS11795
gene id: 2025808:CCZ37_RS11795
uniprot id: A0A223N069
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2025808:CCZ37 RS01615
gene id: 2025808:CCZ37_RS01615
uniprot id: A0A223MVL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

2025808:CCZ37 RS03090
gene id: 2025808:CCZ37_RS03090
uniprot id: A0A223MVP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.

2025808:CCZ37 RS14610
gene id: 2025808:CCZ37_RS14610
uniprot id: A0A223N1L7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS00425
gene id: 2025808:CCZ37_RS00425
uniprot id: A0A223MUK4
names: Similarity
messages: Belongs to the GSP N family.

2025808:CCZ37 RS03275
gene id: 2025808:CCZ37_RS03275
uniprot id: A0A223MVS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

2025808:CCZ37 RS13010
gene id: 2025808:CCZ37_RS13010
uniprot id: A0A223N165
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2025808:CCZ37 RS15120
gene id: 2025808:CCZ37_RS15120
uniprot id: A0A223N2J4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

2025808:CCZ37 RS05010
gene id: 2025808:CCZ37_RS05010
uniprot id: A0A223MWP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2025808:CCZ37 RS00795
gene id: 2025808:CCZ37_RS00795
uniprot id: A0A223MUK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2025808:CCZ37 RS08245
gene id: 2025808:CCZ37_RS08245
uniprot id: A0A223MYM2
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

2025808:CCZ37 RS08800
gene id: 2025808:CCZ37_RS08800
uniprot id: A0A223MYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS09915
gene id: 2025808:CCZ37_RS09915
uniprot id: A0A223MZA5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS05300
gene id: 2025808:CCZ37_RS05300
uniprot id: A0A223MWR3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2025808:CCZ37 RS03745
gene id: 2025808:CCZ37_RS03745
uniprot id: A0A223MW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

2025808:CCZ37 RS01065
gene id: 2025808:CCZ37_RS01065
uniprot id: A0A223MUN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

2025808:CCZ37 RS11945
gene id: 2025808:CCZ37_RS11945
uniprot id: A0A223N0A3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

2025808:CCZ37 RS06365
gene id: 2025808:CCZ37_RS06365
uniprot id: A0A223N157
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2025808:CCZ37 RS11150
gene id: 2025808:CCZ37_RS11150
uniprot id: A0A223N0A0
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS04960
gene id: 2025808:CCZ37_RS04960
uniprot id: A0A223MWM6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2025808:CCZ37 RS14275
gene id: 2025808:CCZ37_RS14275
uniprot id: A0A223N1F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2025808:CCZ37 RS05680
gene id: 2025808:CCZ37_RS05680
uniprot id: A0A223MX09
names: Subunit
messages: Monomer.

2025808:CCZ37 RS07725
gene id: 2025808:CCZ37_RS07725
uniprot id: A0A223MY43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS18090
gene id: 2025808:CCZ37_RS18090
uniprot id: A0A223N3V5
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS00355
gene id: 2025808:CCZ37_RS00355
uniprot id: A0A223MUE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

2025808:CCZ37 RS02815
gene id: 2025808:CCZ37_RS02815
uniprot id: A0A223MVN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2025808:CCZ37 RS04650
gene id: 2025808:CCZ37_RS04650
uniprot id: A0A223MWE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

2025808:CCZ37 RS11445
gene id: 2025808:CCZ37_RS11445
uniprot id: A0A223N075
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2025808:CCZ37 RS06480
gene id: 2025808:CCZ37_RS06480
uniprot id: A0A223MXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2025808:CCZ37 RS01570
gene id: 2025808:CCZ37_RS01570
uniprot id: A0A223MUX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2025808:CCZ37 RS15155
gene id: 2025808:CCZ37_RS15155
uniprot id: A0A223N2A9
names: Similarity
messages: Belongs to the UPF0265 family.

2025808:CCZ37 RS03125
gene id: 2025808:CCZ37_RS03125
uniprot id: A0A223MVT9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2025808:CCZ37 RS11120
gene id: 2025808:CCZ37_RS11120
uniprot id: A0A223N028
names: Similarity
messages: Belongs to the BolA/IbaG family.

2025808:CCZ37 RS10700
gene id: 2025808:CCZ37_RS10700
uniprot id: A0A223MZP2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2025808:CCZ37 RS18715
gene id: 2025808:CCZ37_RS18715
uniprot id: A0A223N3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2025808:CCZ37 RS09140
gene id: 2025808:CCZ37_RS09140
uniprot id: A0A223MYW7
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS11500
gene id: 2025808:CCZ37_RS11500
uniprot id: A0A223N0F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

2025808:CCZ37 RS11565
gene id: 2025808:CCZ37_RS11565
uniprot id: A0A223N0G1
names: Similarity
messages: Belongs to the UPF0270 family.

2025808:CCZ37 RS12105
gene id: 2025808:CCZ37_RS12105
uniprot id: A0A223N0B5
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS04235
gene id: 2025808:CCZ37_RS04235
uniprot id: A0A223N1F0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS08410
gene id: 2025808:CCZ37_RS08410
uniprot id: A0A223MYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

2025808:CCZ37 RS08215
gene id: 2025808:CCZ37_RS08215
uniprot id: A0A223MYX4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2025808:CCZ37 RS05875
gene id: 2025808:CCZ37_RS05875
uniprot id: A0A223MX23
names: Similarity
messages: Belongs to the DEAD box helicase family.

2025808:CCZ37 RS03570
gene id: 2025808:CCZ37_RS03570
uniprot id: A0A223MW30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS08050
gene id: 2025808:CCZ37_RS08050
uniprot id: A0A223MYV1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2025808:CCZ37 RS09505
gene id: 2025808:CCZ37_RS09505
uniprot id: A0A223MZ34
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2025808:CCZ37 RS00405
gene id: 2025808:CCZ37_RS00405
uniprot id: A0A223MUD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS10495
gene id: 2025808:CCZ37_RS10495
uniprot id: A0A223MZK5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2025808:CCZ37 RS06450
gene id: 2025808:CCZ37_RS06450
uniprot id: A0A223MXM8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

2025808:CCZ37 RS07625
gene id: 2025808:CCZ37_RS07625
uniprot id: A0A223MYP4
names: Subcellular Location Annotation
messages: Cytoplasm

2025808:CCZ37 RS01270
gene id: 2025808:CCZ37_RS01270
uniprot id: A0A223MUX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

2025808:CCZ37 RS08010
gene id: 2025808:CCZ37_RS08010
uniprot id: A0A223MY99
names: Similarity
messages: Belongs to the AlaDH/PNT family.

2025808:CCZ37 RS11115
gene id: 2025808:CCZ37_RS11115
uniprot id: A0A223MZV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

2025808:CCZ37 RS08885
gene id: 2025808:CCZ37_RS08885
uniprot id: A0A223MYQ0
names: Similarity
messages: Belongs to the MlaA family.

2025808:CCZ37 RS04630
gene id: 2025808:CCZ37_RS04630
uniprot id: A0A223MX55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

2025808:CCZ37 RS01435
gene id: 2025808:CCZ37_RS01435
uniprot id: A0A223MUS9
names: Similarity
messages: Belongs to the aspartokinase family.

2025808:CCZ37 RS01790
gene id: 2025808:CCZ37_RS01790
uniprot id: A0A223MUZ2
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

2025808:CCZ37 RS00045
gene id: 2025808:CCZ37_RS00045
uniprot id: A0A223MUD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2025808:CCZ37 RS04040
gene id: 2025808:CCZ37_RS04040
uniprot id: A0A223MW68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

2025808:CCZ37 RS14560
gene id: 2025808:CCZ37_RS14560
uniprot id: A0A223N246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS01735
gene id: 2025808:CCZ37_RS01735
uniprot id: A0A223MV01
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

2025808:CCZ37 RS15745
gene id: 2025808:CCZ37_RS15745
uniprot id: A0A223N2A4
names: Subcellular Location Annotation
messages: Cytoplasm

2025808:CCZ37 RS05755
gene id: 2025808:CCZ37_RS05755
uniprot id: A0A223MX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2025808:CCZ37 RS02630
gene id: 2025808:CCZ37_RS02630
uniprot id: A0A223MVN6
names: Similarity
messages: Belongs to the UPF0231 family.

2025808:CCZ37 RS03020
gene id: 2025808:CCZ37_RS03020
uniprot id: A0A223MVL8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2025808:CCZ37 RS06830
gene id: 2025808:CCZ37_RS06830
uniprot id: A0A223MXM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2025808:CCZ37 RS10740
gene id: 2025808:CCZ37_RS10740
uniprot id: A0A223N041
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2025808:CCZ37 RS14910
gene id: 2025808:CCZ37_RS14910
uniprot id: A0A223N266
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2025808:CCZ37 RS07775
gene id: 2025808:CCZ37_RS07775
uniprot id: A0A223MY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

2025808:CCZ37 RS03065
gene id: 2025808:CCZ37_RS03065
uniprot id: A0A223MVU7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2025808:CCZ37 RS00200
gene id: 2025808:CCZ37_RS00200
uniprot id: A0A223MUG5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2025808:CCZ37 RS02365
gene id: 2025808:CCZ37_RS02365
uniprot id: A0A223MV93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

2025808:CCZ37 RS03245
gene id: 2025808:CCZ37_RS03245
uniprot id: A0A223MVZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS04990
gene id: 2025808:CCZ37_RS04990
uniprot id: A0A223MWL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2025808:CCZ37 RS07155
gene id: 2025808:CCZ37_RS07155
uniprot id: A0A223MXT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS02160
gene id: 2025808:CCZ37_RS02160
uniprot id: A0A223MV54
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2025808:CCZ37 RS18415
gene id: 2025808:CCZ37_RS18415
uniprot id: A0A223N400
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2025808:CCZ37 RS11250
gene id: 2025808:CCZ37_RS11250
uniprot id: A0A223N0B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2025808:CCZ37 RS08185
gene id: 2025808:CCZ37_RS08185
uniprot id: A0A223MYC5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2025808:CCZ37 RS10555
gene id: 2025808:CCZ37_RS10555
uniprot id: A0A223MZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2025808:CCZ37 RS03670
gene id: 2025808:CCZ37_RS03670
uniprot id: A0A223MW64
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2025808:CCZ37 RS07880
gene id: 2025808:CCZ37_RS07880
uniprot id: A0A223MYT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

2025808:CCZ37 RS04065
gene id: 2025808:CCZ37_RS04065
uniprot id: A0A223MWG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2025808:CCZ37 RS12230
gene id: 2025808:CCZ37_RS12230
uniprot id: A0A223N0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2025808:CCZ37 RS01055
gene id: 2025808:CCZ37_RS01055
uniprot id: A0A223MUM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2025808:CCZ37 RS05040
gene id: 2025808:CCZ37_RS05040
uniprot id: A0A223MWW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2025808:CCZ37 RS10465
gene id: 2025808:CCZ37_RS10465
uniprot id: A0A223MZK8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS04810
gene id: 2025808:CCZ37_RS04810
uniprot id: A0A223MWM9
names: Similarity
messages: Belongs to the UPF0304 family.

2025808:CCZ37 RS11355
gene id: 2025808:CCZ37_RS11355
uniprot id: A0A223N066
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2025808:CCZ37 RS04025
gene id: 2025808:CCZ37_RS04025
uniprot id: A0A223MW39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2025808:CCZ37 RS08675
gene id: 2025808:CCZ37_RS08675
uniprot id: A0A223MYM6
names: Similarity
messages: Belongs to the pyruvate kinase family.

2025808:CCZ37 RS13555
gene id: 2025808:CCZ37_RS13555
uniprot id: A0A223N170
names: Similarity
messages: Belongs to the UPF0438 family.

2025808:CCZ37 RS09085
gene id: 2025808:CCZ37_RS09085
uniprot id: A0A223MYW0
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

2025808:CCZ37 RS17750
gene id: 2025808:CCZ37_RS17750
uniprot id: A0A223N3D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

2025808:CCZ37 RS11385
gene id: 2025808:CCZ37_RS11385
uniprot id: A0A223N001
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2025808:CCZ37 RS08030
gene id: 2025808:CCZ37_RS08030
uniprot id: A0A223MYG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

2025808:CCZ37 RS02395
gene id: 2025808:CCZ37_RS02395
uniprot id: A0A223MVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

2025808:CCZ37 RS10235
gene id: 2025808:CCZ37_RS10235
uniprot id: A0A223MZG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

2025808:CCZ37 RS01965
gene id: 2025808:CCZ37_RS01965
uniprot id: A0A223MVB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

2025808:CCZ37 RS08080
gene id: 2025808:CCZ37_RS08080
uniprot id: A0A223MYI5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2025808:CCZ37 RS00515
gene id: 2025808:CCZ37_RS00515
uniprot id: A0A223MUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2025808:CCZ37 RS11825
gene id: 2025808:CCZ37_RS11825
uniprot id: A0A223N0K4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2025808:CCZ37 RS13270
gene id: 2025808:CCZ37_RS13270
uniprot id: A0A223N1B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2025808:CCZ37 RS11455
gene id: 2025808:CCZ37_RS11455
uniprot id: A0A223N087
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2025808:CCZ37 RS01465
gene id: 2025808:CCZ37_RS01465
uniprot id: A0A223N1E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

2025808:CCZ37 RS10935
gene id: 2025808:CCZ37_RS10935
uniprot id: A0A223MZU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2025808:CCZ37 RS05620
gene id: 2025808:CCZ37_RS05620
uniprot id: A0A223MX42
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

2025808:CCZ37 RS15270
gene id: 2025808:CCZ37_RS15270
uniprot id: A0A223N2C6
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

2025808:CCZ37 RS11910
gene id: 2025808:CCZ37_RS11910
uniprot id: A0A223N089
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

2025808:CCZ37 RS13200
gene id: 2025808:CCZ37_RS13200
uniprot id: A0A223N172
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

2025808:CCZ37 RS09650
gene id: 2025808:CCZ37_RS09650
uniprot id: A0A223MZ37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2025808:CCZ37 RS02800
gene id: 2025808:CCZ37_RS02800
uniprot id: A0A223MVI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2025808:CCZ37 RS11395
gene id: 2025808:CCZ37_RS11395
uniprot id: A0A223N065
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2025808:CCZ37 RS10670
gene id: 2025808:CCZ37_RS10670
uniprot id: A0A223MZY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

2025808:CCZ37 RS10000
gene id: 2025808:CCZ37_RS10000
uniprot id: A0A223MZB2
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

2025808:CCZ37 RS09900
gene id: 2025808:CCZ37_RS09900
uniprot id: A0A223MZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

2025808:CCZ37 RS10625
gene id: 2025808:CCZ37_RS10625
uniprot id: A0A223MZP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2025808:CCZ37 RS09135
gene id: 2025808:CCZ37_RS09135
uniprot id: A0A223MYW6
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS12150
gene id: 2025808:CCZ37_RS12150
uniprot id: A0A223N0J2
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

2025808:CCZ37 RS08340
gene id: 2025808:CCZ37_RS08340
uniprot id: A0A223MYH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2025808:CCZ37 RS04270
gene id: 2025808:CCZ37_RS04270
uniprot id: A0A223MWJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

2025808:CCZ37 RS08740
gene id: 2025808:CCZ37_RS08740
uniprot id: A0A223MYY7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2025808:CCZ37 RS17760
gene id: 2025808:CCZ37_RS17760
uniprot id: A0A223N339
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2025808:CCZ37 RS11450
gene id: 2025808:CCZ37_RS11450
uniprot id: A0A223N0E2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2025808:CCZ37 RS12615
gene id: 2025808:CCZ37_RS12615
uniprot id: A0A223N0K9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2025808:CCZ37 RS09930
gene id: 2025808:CCZ37_RS09930
uniprot id: A0A223MZA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2025808:CCZ37 RS02535
gene id: 2025808:CCZ37_RS02535
uniprot id: A0A223MVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2025808:CCZ37 RS01015
gene id: 2025808:CCZ37_RS01015
uniprot id: A0A223MUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2025808:CCZ37 RS18630
gene id: 2025808:CCZ37_RS18630
uniprot id: A0A223N424
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

2025808:CCZ37 RS09410
gene id: 2025808:CCZ37_RS09410
uniprot id: A0A223MZ08
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2025808:CCZ37 RS16945
gene id: 2025808:CCZ37_RS16945
uniprot id: A0A223N2V9
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS06225
gene id: 2025808:CCZ37_RS06225
uniprot id: A0A223MXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS04790
gene id: 2025808:CCZ37_RS04790
uniprot id: A0A223MXB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

2025808:CCZ37 RS15310
gene id: 2025808:CCZ37_RS15310
uniprot id: A0A223N2C1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

2025808:CCZ37 RS09405
gene id: 2025808:CCZ37_RS09405
uniprot id: A0A223MZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2025808:CCZ37 RS15095
gene id: 2025808:CCZ37_RS15095
uniprot id: A0A223N239
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2025808:CCZ37 RS12440
gene id: 2025808:CCZ37_RS12440
uniprot id: A0A223N0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS18710
gene id: 2025808:CCZ37_RS18710
uniprot id: A0A223N3V7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

2025808:CCZ37 RS03415
gene id: 2025808:CCZ37_RS03415
uniprot id: A0A223MWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

2025808:CCZ37 RS08810
gene id: 2025808:CCZ37_RS08810
uniprot id: A0A223MYP7
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS09320
gene id: 2025808:CCZ37_RS09320
uniprot id: A0A223MYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

2025808:CCZ37 RS01845
gene id: 2025808:CCZ37_RS01845
uniprot id: A0A223MV24
names: Similarity
messages: Belongs to the GSP E family.

2025808:CCZ37 RS16365
gene id: 2025808:CCZ37_RS16365
uniprot id: A0A223N2I8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2025808:CCZ37 RS06105
gene id: 2025808:CCZ37_RS06105
uniprot id: A0A223MXB8
names: Similarity
messages: Belongs to the citrate synthase family.

2025808:CCZ37 RS11375
gene id: 2025808:CCZ37_RS11375
uniprot id: A0A223N002
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2025808:CCZ37 RS00450
gene id: 2025808:CCZ37_RS00450
uniprot id: A0A223MUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

2025808:CCZ37 RS14375
gene id: 2025808:CCZ37_RS14375
uniprot id: A0A223N1L5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2025808:CCZ37 RS00615
gene id: 2025808:CCZ37_RS00615
uniprot id: A0A223MUP1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

2025808:CCZ37 RS02640
gene id: 2025808:CCZ37_RS02640
uniprot id: A0A223MVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

2025808:CCZ37 RS08770
gene id: 2025808:CCZ37_RS08770
uniprot id: A0A223MYP3
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

2025808:CCZ37 RS12435
gene id: 2025808:CCZ37_RS12435
uniprot id: A0A223N0H3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2025808:CCZ37 RS01885
gene id: 2025808:CCZ37_RS01885
uniprot id: A0A223N189
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2025808:CCZ37 RS06790
gene id: 2025808:CCZ37_RS06790
uniprot id: A0A223MXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Amino-acid racemase able to utilize a broad range of substrates.
messages: Belongs to the alanine racemase family. Bsr subfamily.
messages: Periplasm

2025808:CCZ37 RS09675
gene id: 2025808:CCZ37_RS09675
uniprot id: A0A223MZ62
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

2025808:CCZ37 RS11940
gene id: 2025808:CCZ37_RS11940
uniprot id: A0A223N0E7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2025808:CCZ37 RS03300
gene id: 2025808:CCZ37_RS03300
uniprot id: A0A223MVY2
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

2025808:CCZ37 RS00980
gene id: 2025808:CCZ37_RS00980
uniprot id: A0A223MUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

2025808:CCZ37 RS11475
gene id: 2025808:CCZ37_RS11475
uniprot id: A0A223N015
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2025808:CCZ37 RS05340
gene id: 2025808:CCZ37_RS05340
uniprot id: A0A223MX29
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS03545
gene id: 2025808:CCZ37_RS03545
uniprot id: A0A223MW01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2025808:CCZ37 RS04255
gene id: 2025808:CCZ37_RS04255
uniprot id: A0A223MW73
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS14620
gene id: 2025808:CCZ37_RS14620
uniprot id: A0A223N1U9
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

2025808:CCZ37 RS02700
gene id: 2025808:CCZ37_RS02700
uniprot id: A0A223MW45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS04140
gene id: 2025808:CCZ37_RS04140
uniprot id: A0A223MW94
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2025808:CCZ37 RS04510
gene id: 2025808:CCZ37_RS04510
uniprot id: A0A223MWC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

2025808:CCZ37 RS12135
gene id: 2025808:CCZ37_RS12135
uniprot id: A0A223N0R5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2025808:CCZ37 RS02730
gene id: 2025808:CCZ37_RS02730
uniprot id: A0A223MVF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2025808:CCZ37 RS05310
gene id: 2025808:CCZ37_RS05310
uniprot id: A0A223MXJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2025808:CCZ37 RS06745
gene id: 2025808:CCZ37_RS06745
uniprot id: A0A223MXL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

2025808:CCZ37 RS16405
gene id: 2025808:CCZ37_RS16405
uniprot id: A0A223N2N4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

2025808:CCZ37 RS04295
gene id: 2025808:CCZ37_RS04295
uniprot id: A0A223MWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2025808:CCZ37 RS14470
gene id: 2025808:CCZ37_RS14470
uniprot id: A0A223N1T4
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

2025808:CCZ37 RS14855
gene id: 2025808:CCZ37_RS14855
uniprot id: A0A223N2C8
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

2025808:CCZ37 RS06580
gene id: 2025808:CCZ37_RS06580
uniprot id: A0A223MXI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2025808:CCZ37 RS07600
gene id: 2025808:CCZ37_RS07600
uniprot id: A0A223MY38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

2025808:CCZ37 RS09490
gene id: 2025808:CCZ37_RS09490
uniprot id: A0A223MZ26
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

2025808:CCZ37 RS13070
gene id: 2025808:CCZ37_RS13070
uniprot id: A0A223N0S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2025808:CCZ37 RS03290
gene id: 2025808:CCZ37_RS03290
uniprot id: A0A223MVR1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2025808:CCZ37 RS01855
gene id: 2025808:CCZ37_RS01855
uniprot id: A0A223MV92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2025808:CCZ37 RS08190
gene id: 2025808:CCZ37_RS08190
uniprot id: A0A223MYF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS02780
gene id: 2025808:CCZ37_RS02780
uniprot id: A0A223MVK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

2025808:CCZ37 RS14595
gene id: 2025808:CCZ37_RS14595
uniprot id: A0A223N222
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2025808:CCZ37 RS10065
gene id: 2025808:CCZ37_RS10065
uniprot id: A0A223MZU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

2025808:CCZ37 RS09240
gene id: 2025808:CCZ37_RS09240
uniprot id: A0A223MYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2025808:CCZ37 RS15425
gene id: 2025808:CCZ37_RS15425
uniprot id: A0A223N2C7
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

2025808:CCZ37 RS05655
gene id: 2025808:CCZ37_RS05655
uniprot id: A0A223MXA1
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS08825
gene id: 2025808:CCZ37_RS08825
uniprot id: A0A223MYP6
names: Similarity
messages: Belongs to the UPF0352 family.

2025808:CCZ37 RS08755
gene id: 2025808:CCZ37_RS08755
uniprot id: A0A223MYN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

2025808:CCZ37 RS10835
gene id: 2025808:CCZ37_RS10835
uniprot id: A0A223MZS4
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

2025808:CCZ37 RS09760
gene id: 2025808:CCZ37_RS09760
uniprot id: A0A223MZ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2025808:CCZ37 RS09205
gene id: 2025808:CCZ37_RS09205
uniprot id: A0A223MYV3
names: Similarity
messages: Belongs to the UPF0115 family.

2025808:CCZ37 RS17515
gene id: 2025808:CCZ37_RS17515
uniprot id: A0A223N334
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

2025808:CCZ37 RS09775
gene id: 2025808:CCZ37_RS09775
uniprot id: A0A223MZF1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2025808:CCZ37 RS12065
gene id: 2025808:CCZ37_RS12065
uniprot id: A0A223N0B3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

2025808:CCZ37 RS06100
gene id: 2025808:CCZ37_RS06100
uniprot id: A0A223MX66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

2025808:CCZ37 RS15515
gene id: 2025808:CCZ37_RS15515
uniprot id: A0A223N2P2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2025808:CCZ37 RS11735
gene id: 2025808:CCZ37_RS11735
uniprot id: A0A223N059
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

2025808:CCZ37 RS09715
gene id: 2025808:CCZ37_RS09715
uniprot id: A0A223MZE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2025808:CCZ37 RS01685
gene id: 2025808:CCZ37_RS01685
uniprot id: A0A223MUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2025808:CCZ37 RS11705
gene id: 2025808:CCZ37_RS11705
uniprot id: A0A223N050
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2025808:CCZ37 RS00645
gene id: 2025808:CCZ37_RS00645
uniprot id: A0A223MUJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS10560
gene id: 2025808:CCZ37_RS10560
uniprot id: A0A223MZV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2025808:CCZ37 RS06305
gene id: 2025808:CCZ37_RS06305
uniprot id: A0A223MXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.

2025808:CCZ37 RS13550
gene id: 2025808:CCZ37_RS13550
uniprot id: A0A223N1N5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS08795
gene id: 2025808:CCZ37_RS08795
uniprot id: A0A223MYZ8
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

2025808:CCZ37 RS11935
gene id: 2025808:CCZ37_RS11935
uniprot id: A0A223N095
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2025808:CCZ37 RS01200
gene id: 2025808:CCZ37_RS01200
uniprot id: A0A223MUQ0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

2025808:CCZ37 RS08205
gene id: 2025808:CCZ37_RS08205
uniprot id: A0A223MYD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

2025808:CCZ37 RS05235
gene id: 2025808:CCZ37_RS05235
uniprot id: A0A223MWT0
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

2025808:CCZ37 RS07710
gene id: 2025808:CCZ37_RS07710
uniprot id: A0A223MYA5
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

2025808:CCZ37 RS05770
gene id: 2025808:CCZ37_RS05770
uniprot id: A0A223MX03
names: Similarity
messages: Belongs to the PspA/IM30 family.

2025808:CCZ37 RS04585
gene id: 2025808:CCZ37_RS04585
uniprot id: A0A223MWF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

2025808:CCZ37 RS08475
gene id: 2025808:CCZ37_RS08475
uniprot id: A0A223MYH5
names: Similarity
messages: Belongs to the MoaD family.

2025808:CCZ37 RS08670
gene id: 2025808:CCZ37_RS08670
uniprot id: A0A223MYL2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2025808:CCZ37 RS11465
gene id: 2025808:CCZ37_RS11465
uniprot id: A0A223N078
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2025808:CCZ37 RS11215
gene id: 2025808:CCZ37_RS11215
uniprot id: A0A223N029
names: Similarity
messages: Belongs to the UPF0307 family.

2025808:CCZ37 RS03805
gene id: 2025808:CCZ37_RS03805
uniprot id: A0A223MW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

2025808:CCZ37 RS05395
gene id: 2025808:CCZ37_RS05395
uniprot id: A0A223MX39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

2025808:CCZ37 RS08420
gene id: 2025808:CCZ37_RS08420
uniprot id: A0A223MYI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

2025808:CCZ37 RS01190
gene id: 2025808:CCZ37_RS01190
uniprot id: A0A223MUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2025808:CCZ37 RS01030
gene id: 2025808:CCZ37_RS01030
uniprot id: A0A223MUM3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2025808:CCZ37 RS02195
gene id: 2025808:CCZ37_RS02195
uniprot id: A0A223MVV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

2025808:CCZ37 RS10825
gene id: 2025808:CCZ37_RS10825
uniprot id: A0A223N000
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

2025808:CCZ37 RS13265
gene id: 2025808:CCZ37_RS13265
uniprot id: A0A223N0U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2025808:CCZ37 RS05885
gene id: 2025808:CCZ37_RS05885
uniprot id: A0A223MXT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2025808:CCZ37 RS07895
gene id: 2025808:CCZ37_RS07895
uniprot id: A0A223MY84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

2025808:CCZ37 RS10430
gene id: 2025808:CCZ37_RS10430
uniprot id: A0A223MZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2025808:CCZ37 RS11435
gene id: 2025808:CCZ37_RS11435
uniprot id: A0A223N011
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2025808:CCZ37 RS01280
gene id: 2025808:CCZ37_RS01280
uniprot id: A0A223MUX8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2025808:CCZ37 RS10125
gene id: 2025808:CCZ37_RS10125
uniprot id: A0A223MZD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2025808:CCZ37 RS13075
gene id: 2025808:CCZ37_RS13075
uniprot id: A0A223N181
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2025808:CCZ37 RS05975
gene id: 2025808:CCZ37_RS05975
uniprot id: A0A223MXB6
names: Subcellular Location Annotation
messages: Cytoplasm

2025808:CCZ37 RS00535
gene id: 2025808:CCZ37_RS00535
uniprot id: A0A223MUM4
names: Similarity
messages: Belongs to the thioredoxin family.

2025808:CCZ37 RS13310
gene id: 2025808:CCZ37_RS13310
uniprot id: A0A223N0X0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS06625
gene id: 2025808:CCZ37_RS06625
uniprot id: A0A223MXJ0
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

2025808:CCZ37 RS01345
gene id: 2025808:CCZ37_RS01345
uniprot id: A0A223MUV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS05025
gene id: 2025808:CCZ37_RS05025
uniprot id: A0A223MWR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2025808:CCZ37 RS01250
gene id: 2025808:CCZ37_RS01250
uniprot id: A0A223MUR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2025808:CCZ37 RS13035
gene id: 2025808:CCZ37_RS13035
uniprot id: A0A223N0U5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2025808:CCZ37 RS08260
gene id: 2025808:CCZ37_RS08260
uniprot id: A0A223MYE2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2025808:CCZ37 RS09115
gene id: 2025808:CCZ37_RS09115
uniprot id: A0A223MYU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

2025808:CCZ37 RS09960
gene id: 2025808:CCZ37_RS09960
uniprot id: A0A223MZS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2025808:CCZ37 RS09955
gene id: 2025808:CCZ37_RS09955
uniprot id: A0A223MZ98
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2025808:CCZ37 RS02235
gene id: 2025808:CCZ37_RS02235
uniprot id: A0A223MV80
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2025808:CCZ37 RS18315
gene id: 2025808:CCZ37_RS18315
uniprot id: A0A223N3Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

2025808:CCZ37 RS02180
gene id: 2025808:CCZ37_RS02180
uniprot id: A0A223MVC7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

2025808:CCZ37 RS10610
gene id: 2025808:CCZ37_RS10610
uniprot id: A0A223MZM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2025808:CCZ37 RS08500
gene id: 2025808:CCZ37_RS08500
uniprot id: A0A223MYI7
names: Subunit
messages: Monomer.

2025808:CCZ37 RS01275
gene id: 2025808:CCZ37_RS01275
uniprot id: A0A223MUR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2025808:CCZ37 RS06000
gene id: 2025808:CCZ37_RS06000
uniprot id: A0A223MX81
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

2025808:CCZ37 RS02145
gene id: 2025808:CCZ37_RS02145
uniprot id: A0A223MVU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2025808:CCZ37 RS05080
gene id: 2025808:CCZ37_RS05080
uniprot id: A0A223MWM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2025808:CCZ37 RS06875
gene id: 2025808:CCZ37_RS06875
uniprot id: A0A223MXL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS06645
gene id: 2025808:CCZ37_RS06645
uniprot id: A0A223MXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS07875
gene id: 2025808:CCZ37_RS07875
uniprot id: A0A223MY70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

2025808:CCZ37 RS10790
gene id: 2025808:CCZ37_RS10790
uniprot id: A0A223N051
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2025808:CCZ37 RS11865
gene id: 2025808:CCZ37_RS11865
uniprot id: A0A223N082
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2025808:CCZ37 RS00760
gene id: 2025808:CCZ37_RS00760
uniprot id: A0A223MUL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2025808:CCZ37 RS06900
gene id: 2025808:CCZ37_RS06900
uniprot id: A0A223MXM9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2025808:CCZ37 RS00540
gene id: 2025808:CCZ37_RS00540
uniprot id: A0A223MUF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2025808:CCZ37 RS09055
gene id: 2025808:CCZ37_RS09055
uniprot id: A0A223MYS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2025808:CCZ37 RS11770
gene id: 2025808:CCZ37_RS11770
uniprot id: A0A223N0K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2025808:CCZ37 RS08020
gene id: 2025808:CCZ37_RS08020
uniprot id: A0A223MYA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS01680
gene id: 2025808:CCZ37_RS01680
uniprot id: A0A223MVM5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2025808:CCZ37 RS07905
gene id: 2025808:CCZ37_RS07905
uniprot id: A0A223MY98
names: Similarity
messages: Belongs to the YciI family.

2025808:CCZ37 RS01060
gene id: 2025808:CCZ37_RS01060
uniprot id: A0A223MUR6
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

2025808:CCZ37 RS10885
gene id: 2025808:CCZ37_RS10885
uniprot id: A0A223MZT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

2025808:CCZ37 RS11040
gene id: 2025808:CCZ37_RS11040
uniprot id: A0A223MZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2025808:CCZ37 RS11160
gene id: 2025808:CCZ37_RS11160
uniprot id: A0A223MZV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

2025808:CCZ37 RS03360
gene id: 2025808:CCZ37_RS03360
uniprot id: A0A223MVY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2025808:CCZ37 RS06370
gene id: 2025808:CCZ37_RS06370
uniprot id: A0A223MXB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2025808:CCZ37 RS00630
gene id: 2025808:CCZ37_RS00630
uniprot id: A0A223MUM7
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

2025808:CCZ37 RS09680
gene id: 2025808:CCZ37_RS09680
uniprot id: A0A223MZM3
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

2025808:CCZ37 RS09605
gene id: 2025808:CCZ37_RS09605
uniprot id: A0A223MZ41
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

2025808:CCZ37 RS13860
gene id: 2025808:CCZ37_RS13860
uniprot id: A0A223N1P5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS04210
gene id: 2025808:CCZ37_RS04210
uniprot id: A0A223MW70
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2025808:CCZ37 RS03675
gene id: 2025808:CCZ37_RS03675
uniprot id: A0A223N0X6
names: Similarity
messages: Belongs to the UPF0178 family.

2025808:CCZ37 RS04755
gene id: 2025808:CCZ37_RS04755
uniprot id: A0A223MWL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

2025808:CCZ37 RS07610
gene id: 2025808:CCZ37_RS07610
uniprot id: A0A223MY65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2025808:CCZ37 RS06470
gene id: 2025808:CCZ37_RS06470
uniprot id: A0A223MY09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2025808:CCZ37 RS08335
gene id: 2025808:CCZ37_RS08335
uniprot id: A0A223MYG2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2025808:CCZ37 RS12340
gene id: 2025808:CCZ37_RS12340
uniprot id: A0A223N0V2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2025808:CCZ37 RS10880
gene id: 2025808:CCZ37_RS10880
uniprot id: A0A223N007
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

2025808:CCZ37 RS12880
gene id: 2025808:CCZ37_RS12880
uniprot id: A0A223N121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS13210
gene id: 2025808:CCZ37_RS13210
uniprot id: A0A223N0V4
names: Similarity
messages: Belongs to the IMPACT family.

2025808:CCZ37 RS11205
gene id: 2025808:CCZ37_RS11205
uniprot id: A0A223N031
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2025808:CCZ37 RS02445
gene id: 2025808:CCZ37_RS02445
uniprot id: A0A223MVC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2025808:CCZ37 RS15490
gene id: 2025808:CCZ37_RS15490
uniprot id: A0A223N2T1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2025808:CCZ37 RS00725
gene id: 2025808:CCZ37_RS00725
uniprot id: A0A223MUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

2025808:CCZ37 RS05420
gene id: 2025808:CCZ37_RS05420
uniprot id: A0A223MWW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

2025808:CCZ37 RS00070
gene id: 2025808:CCZ37_RS00070
uniprot id: A0A223MUA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS03040
gene id: 2025808:CCZ37_RS03040
uniprot id: A0A223MVN8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

2025808:CCZ37 RS12160
gene id: 2025808:CCZ37_RS12160
uniprot id: A0A223N0C2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

2025808:CCZ37 RS03190
gene id: 2025808:CCZ37_RS03190
uniprot id: A0A223MVP0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2025808:CCZ37 RS11460
gene id: 2025808:CCZ37_RS11460
uniprot id: A0A223N012
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2025808:CCZ37 RS11490
gene id: 2025808:CCZ37_RS11490
uniprot id: A0A223N019
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2025808:CCZ37 RS04980
gene id: 2025808:CCZ37_RS04980
uniprot id: A0A223MWW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2025808:CCZ37 RS10340
gene id: 2025808:CCZ37_RS10340
uniprot id: A0A223MZH3
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

2025808:CCZ37 RS08295
gene id: 2025808:CCZ37_RS08295
uniprot id: A0A223MYP1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2025808:CCZ37 RS02440
gene id: 2025808:CCZ37_RS02440
uniprot id: A0A223MVZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2025808:CCZ37 RS14165
gene id: 2025808:CCZ37_RS14165
uniprot id: A0A223N1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS01800
gene id: 2025808:CCZ37_RS01800
uniprot id: A0A223MUY6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS08705
gene id: 2025808:CCZ37_RS08705
uniprot id: A0A223MZ53
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS11955
gene id: 2025808:CCZ37_RS11955
uniprot id: A0A223N0G5
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

2025808:CCZ37 RS04680
gene id: 2025808:CCZ37_RS04680
uniprot id: A0A223MWN0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

2025808:CCZ37 RS01675
gene id: 2025808:CCZ37_RS01675
uniprot id: A0A223MV31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2025808:CCZ37 RS08480
gene id: 2025808:CCZ37_RS08480
uniprot id: A0A223MZ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

2025808:CCZ37 RS00210
gene id: 2025808:CCZ37_RS00210
uniprot id: A0A223MUH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

2025808:CCZ37 RS13715
gene id: 2025808:CCZ37_RS13715
uniprot id: A0A223N1L8
names: Similarity
messages: Belongs to the GST superfamily.

2025808:CCZ37 RS00385
gene id: 2025808:CCZ37_RS00385
uniprot id: A0A223MV38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

2025808:CCZ37 RS03660
gene id: 2025808:CCZ37_RS03660
uniprot id: A0A223MVX9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

2025808:CCZ37 RS10800
gene id: 2025808:CCZ37_RS10800
uniprot id: A0A223N124
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2025808:CCZ37 RS00205
gene id: 2025808:CCZ37_RS00205
uniprot id: A0A223MUA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

2025808:CCZ37 RS15000
gene id: 2025808:CCZ37_RS15000
uniprot id: A0A223N1X7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2025808:CCZ37 RS09420
gene id: 2025808:CCZ37_RS09420
uniprot id: A0A223MZ25
names: Similarity
messages: Belongs to the ArsC family.

2025808:CCZ37 RS03315
gene id: 2025808:CCZ37_RS03315
uniprot id: A0A223MWF5
names: Similarity
messages: Belongs to the HesB/IscA family.

2025808:CCZ37 RS15005
gene id: 2025808:CCZ37_RS15005
uniprot id: A0A223N1V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

2025808:CCZ37 RS09245
gene id: 2025808:CCZ37_RS09245
uniprot id: A0A223MZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2025808:CCZ37 RS03560
gene id: 2025808:CCZ37_RS03560
uniprot id: A0A223MW44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2025808:CCZ37 RS13570
gene id: 2025808:CCZ37_RS13570
uniprot id: A0A223N194
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS11240
gene id: 2025808:CCZ37_RS11240
uniprot id: A0A223MZY2
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

2025808:CCZ37 RS08070
gene id: 2025808:CCZ37_RS08070
uniprot id: A0A223MYB1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2025808:CCZ37 RS01220
gene id: 2025808:CCZ37_RS01220
uniprot id: A0A223MUW7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2025808:CCZ37 RS09480
gene id: 2025808:CCZ37_RS09480
uniprot id: A0A223MZB1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2025808:CCZ37 RS12445
gene id: 2025808:CCZ37_RS12445
uniprot id: A0A223N0W5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

2025808:CCZ37 RS18180
gene id: 2025808:CCZ37_RS18180
uniprot id: A0A223N3K3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

2025808:CCZ37 RS01660
gene id: 2025808:CCZ37_RS01660
uniprot id: A0A223MV43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

2025808:CCZ37 RS14310
gene id: 2025808:CCZ37_RS14310
uniprot id: A0A223N1Y2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

2025808:CCZ37 RS09325
gene id: 2025808:CCZ37_RS09325
uniprot id: A0A223MZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

2025808:CCZ37 RS04180
gene id: 2025808:CCZ37_RS04180
uniprot id: A0A223MWE8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2025808:CCZ37 RS11775
gene id: 2025808:CCZ37_RS11775
uniprot id: A0A223N0J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2025808:CCZ37 RS06250
gene id: 2025808:CCZ37_RS06250
uniprot id: A0A223MXC5
names: Similarity
messages: Belongs to the UPF0234 family.

2025808:CCZ37 RS02975
gene id: 2025808:CCZ37_RS02975
uniprot id: A0A223MVR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS02140
gene id: 2025808:CCZ37_RS02140
uniprot id: A0A223MVA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2025808:CCZ37 RS13255
gene id: 2025808:CCZ37_RS13255
uniprot id: A0A223N1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2025808:CCZ37 RS08350
gene id: 2025808:CCZ37_RS08350
uniprot id: A0A223MYQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS05505
gene id: 2025808:CCZ37_RS05505
uniprot id: A0A223MWV5
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS06425
gene id: 2025808:CCZ37_RS06425
uniprot id: A0A223MXC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2025808:CCZ37 RS15135
gene id: 2025808:CCZ37_RS15135
uniprot id: A0A223N2H6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

2025808:CCZ37 RS16785
gene id: 2025808:CCZ37_RS16785
uniprot id: A0A223N2S3
names: Similarity
messages: Belongs to the RelE toxin family.

2025808:CCZ37 RS02880
gene id: 2025808:CCZ37_RS02880
uniprot id: A0A223MVL1
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

2025808:CCZ37 RS03725
gene id: 2025808:CCZ37_RS03725
uniprot id: A0A223MVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

2025808:CCZ37 RS14565
gene id: 2025808:CCZ37_RS14565
uniprot id: A0A223N1T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2025808:CCZ37 RS10505
gene id: 2025808:CCZ37_RS10505
uniprot id: A0A223MZK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2025808:CCZ37 RS15460
gene id: 2025808:CCZ37_RS15460
uniprot id: A0A223N2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS11430
gene id: 2025808:CCZ37_RS11430
uniprot id: A0A223N081
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2025808:CCZ37 RS01245
gene id: 2025808:CCZ37_RS01245
uniprot id: A0A223MUT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2025808:CCZ37 RS02230
gene id: 2025808:CCZ37_RS02230
uniprot id: A0A223MVD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2025808:CCZ37 RS14380
gene id: 2025808:CCZ37_RS14380
uniprot id: A0A223N1H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

2025808:CCZ37 RS13250
gene id: 2025808:CCZ37_RS13250
uniprot id: A0A223N182
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2025808:CCZ37 RS08320
gene id: 2025808:CCZ37_RS08320
uniprot id: A0A223MYF8
names: Similarity
messages: Belongs to the UPF0260 family.

2025808:CCZ37 RS03255
gene id: 2025808:CCZ37_RS03255
uniprot id: A0A223MVQ9
names: Cofactor
messages: Can also use Mn(2+) ion.

2025808:CCZ37 RS02250
gene id: 2025808:CCZ37_RS02250
uniprot id: A0A223MV90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2025808:CCZ37 RS02380
gene id: 2025808:CCZ37_RS02380
uniprot id: A0A223MVA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2025808:CCZ37 RS15245
gene id: 2025808:CCZ37_RS15245
uniprot id: A0A223N2B5
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS00060
gene id: 2025808:CCZ37_RS00060
uniprot id: A0A223MUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

2025808:CCZ37 RS05030
gene id: 2025808:CCZ37_RS05030
uniprot id: A0A223MWM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2025808:CCZ37 RS08780
gene id: 2025808:CCZ37_RS08780
uniprot id: A0A223N130
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2025808:CCZ37 RS03665
gene id: 2025808:CCZ37_RS03665
uniprot id: A0A223MW96
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2025808:CCZ37 RS01830
gene id: 2025808:CCZ37_RS01830
uniprot id: A0A223MV12
names: Similarity
messages: Belongs to the YggT family.

2025808:CCZ37 RS03990
gene id: 2025808:CCZ37_RS03990
uniprot id: A0A223MW58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2025808:CCZ37 RS09050
gene id: 2025808:CCZ37_RS09050
uniprot id: A0A223N116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS04785
gene id: 2025808:CCZ37_RS04785
uniprot id: A0A223MWQ2
names: Similarity
messages: Belongs to the UPF0434 family.

2025808:CCZ37 RS14350
gene id: 2025808:CCZ37_RS14350
uniprot id: A0A223N1Y5
names: Subcellular Location Annotation
messages: Cytoplasm

2025808:CCZ37 RS12130
gene id: 2025808:CCZ37_RS12130
uniprot id: A0A223N0R1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2025808:CCZ37 RS01265
gene id: 2025808:CCZ37_RS01265
uniprot id: A0A223MUZ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2025808:CCZ37 RS04855
gene id: 2025808:CCZ37_RS04855
uniprot id: A0A223MWK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2025808:CCZ37 RS02410
gene id: 2025808:CCZ37_RS02410
uniprot id: A0A223MVC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS13150
gene id: 2025808:CCZ37_RS13150
uniprot id: A0A223N1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2025808:CCZ37 RS04560
gene id: 2025808:CCZ37_RS04560
uniprot id: A0A223MWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS04280
gene id: 2025808:CCZ37_RS04280
uniprot id: A0A223MW87
names: Similarity
messages: Belongs to the glyoxalase I family.

2025808:CCZ37 RS08760
gene id: 2025808:CCZ37_RS08760
uniprot id: A0A223MZ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

2025808:CCZ37 RS07770
gene id: 2025808:CCZ37_RS07770
uniprot id: A0A223MY53
names: Subunit
messages: Monomer.

2025808:CCZ37 RS17570
gene id: 2025808:CCZ37_RS17570
uniprot id: A0A223N3J1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2025808:CCZ37 RS03005
gene id: 2025808:CCZ37_RS03005
uniprot id: A0A223MVL2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

2025808:CCZ37 RS13235
gene id: 2025808:CCZ37_RS13235
uniprot id: A0A223N1B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

2025808:CCZ37 RS10680
gene id: 2025808:CCZ37_RS10680
uniprot id: A0A223MZP4
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

2025808:CCZ37 RS01040
gene id: 2025808:CCZ37_RS01040
uniprot id: A0A223MVD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2025808:CCZ37 RS05810
gene id: 2025808:CCZ37_RS05810
uniprot id: A0A223MXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS12620
gene id: 2025808:CCZ37_RS12620
uniprot id: A0A223N0K0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2025808:CCZ37 RS04675
gene id: 2025808:CCZ37_RS04675
uniprot id: A0A223MWF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2025808:CCZ37 RS08450
gene id: 2025808:CCZ37_RS08450
uniprot id: A0A223MYJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

2025808:CCZ37 RS11570
gene id: 2025808:CCZ37_RS11570
uniprot id: A0A223N0F8
names: Similarity
messages: Belongs to the phosphoribulokinase family.

2025808:CCZ37 RS15615
gene id: 2025808:CCZ37_RS15615
uniprot id: A0A223N2V5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

2025808:CCZ37 RS11970
gene id: 2025808:CCZ37_RS11970
uniprot id: A0A223N0N0
names: Similarity
messages: Belongs to the FBPase class 2 family.

2025808:CCZ37 RS10230
gene id: 2025808:CCZ37_RS10230
uniprot id: A0A223MZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2025808:CCZ37 RS11915
gene id: 2025808:CCZ37_RS11915
uniprot id: A0A223N091
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2025808:CCZ37 RS11180
gene id: 2025808:CCZ37_RS11180
uniprot id: A0A223N037
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2025808:CCZ37 RS02325
gene id: 2025808:CCZ37_RS02325
uniprot id: A0A223MV91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

2025808:CCZ37 RS04315
gene id: 2025808:CCZ37_RS04315
uniprot id: A0A223MWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2025808:CCZ37 RS09425
gene id: 2025808:CCZ37_RS09425
uniprot id: A0A223MZA2
names: Similarity
messages: Belongs to the WrbA family.

2025808:CCZ37 RS09010
gene id: 2025808:CCZ37_RS09010
uniprot id: A0A223MYT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2025808:CCZ37 RS03730
gene id: 2025808:CCZ37_RS03730
uniprot id: A0A223MWA6
names: Similarity
messages: Belongs to the MotB family.

2025808:CCZ37 RS00530
gene id: 2025808:CCZ37_RS00530
uniprot id: A0A223N1D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

2025808:CCZ37 RS15555
gene id: 2025808:CCZ37_RS15555
uniprot id: A0A223N2K5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2025808:CCZ37 RS02600
gene id: 2025808:CCZ37_RS02600
uniprot id: A0A223N1D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS09260
gene id: 2025808:CCZ37_RS09260
uniprot id: A0A223MYZ1
names: Subcellular Location Annotation
messages: Cytoplasm

2025808:CCZ37 RS11370
gene id: 2025808:CCZ37_RS11370
uniprot id: A0A223N003
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2025808:CCZ37 RS01470
gene id: 2025808:CCZ37_RS01470
uniprot id: A0A223MUV5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2025808:CCZ37 RS18765
gene id: 2025808:CCZ37_RS18765
uniprot id: A0A223N3V4
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

2025808:CCZ37 RS02435
gene id: 2025808:CCZ37_RS02435
uniprot id: A0A223MVG6
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

2025808:CCZ37 RS12625
gene id: 2025808:CCZ37_RS12625
uniprot id: A0A223N0U0
names: Similarity
messages: Belongs to the UPF0758 family.

2025808:CCZ37 RS06335
gene id: 2025808:CCZ37_RS06335
uniprot id: A0A223MXK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

2025808:CCZ37 RS01070
gene id: 2025808:CCZ37_RS01070
uniprot id: A0A223MUW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS06010
gene id: 2025808:CCZ37_RS06010
uniprot id: A0A223MX88
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

2025808:CCZ37 RS07865
gene id: 2025808:CCZ37_RS07865
uniprot id: A0A223MYA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS06340
gene id: 2025808:CCZ37_RS06340
uniprot id: A0A223MXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

2025808:CCZ37 RS13340
gene id: 2025808:CCZ37_RS13340
uniprot id: A0A223N179
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS11400
gene id: 2025808:CCZ37_RS11400
uniprot id: A0A223N0D5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2025808:CCZ37 RS04775
gene id: 2025808:CCZ37_RS04775
uniprot id: A0A223N146
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS08605
gene id: 2025808:CCZ37_RS08605
uniprot id: A0A223MZ23
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS11195
gene id: 2025808:CCZ37_RS11195
uniprot id: A0A223MZX2
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

2025808:CCZ37 RS04070
gene id: 2025808:CCZ37_RS04070
uniprot id: A0A223MWD0
names: Similarity
messages: Belongs to the PhoH family.

2025808:CCZ37 RS01580
gene id: 2025808:CCZ37_RS01580
uniprot id: A0A223MUW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2025808:CCZ37 RS00165
gene id: 2025808:CCZ37_RS00165
uniprot id: A0A223MV06
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

2025808:CCZ37 RS00400
gene id: 2025808:CCZ37_RS00400
uniprot id: A0A223MUF5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

2025808:CCZ37 RS12760
gene id: 2025808:CCZ37_RS12760
uniprot id: A0A223N115
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

2025808:CCZ37 RS10035
gene id: 2025808:CCZ37_RS10035
uniprot id: A0A223MZB5
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS00360
gene id: 2025808:CCZ37_RS00360
uniprot id: A0A223MUC5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

2025808:CCZ37 RS02705
gene id: 2025808:CCZ37_RS02705
uniprot id: A0A223MVG9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

2025808:CCZ37 RS03330
gene id: 2025808:CCZ37_RS03330
uniprot id: A0A223MVR7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2025808:CCZ37 RS09810
gene id: 2025808:CCZ37_RS09810
uniprot id: A0A223MZ72
names: Similarity
messages: Belongs to the transglycosylase Slt family.

2025808:CCZ37 RS05270
gene id: 2025808:CCZ37_RS05270
uniprot id: A0A223MX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2025808:CCZ37 RS04260
gene id: 2025808:CCZ37_RS04260
uniprot id: A0A223MWD2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS09450
gene id: 2025808:CCZ37_RS09450
uniprot id: A0A223MZ24
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

2025808:CCZ37 RS02375
gene id: 2025808:CCZ37_RS02375
uniprot id: A0A223MVF8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

2025808:CCZ37 RS01945
gene id: 2025808:CCZ37_RS01945
uniprot id: A0A223MV45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS13300
gene id: 2025808:CCZ37_RS13300
uniprot id: A0A223N192
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

2025808:CCZ37 RS10895
gene id: 2025808:CCZ37_RS10895
uniprot id: A0A223MZT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2025808:CCZ37 RS02835
gene id: 2025808:CCZ37_RS02835
uniprot id: A0A223MVH4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2025808:CCZ37 RS07655
gene id: 2025808:CCZ37_RS07655
uniprot id: A0A223MY42
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2025808:CCZ37 RS01115
gene id: 2025808:CCZ37_RS01115
uniprot id: A0A223MUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

2025808:CCZ37 RS17660
gene id: 2025808:CCZ37_RS17660
uniprot id: A0A223N317
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

2025808:CCZ37 RS10350
gene id: 2025808:CCZ37_RS10350
uniprot id: A0A223N1I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

2025808:CCZ37 RS06215
gene id: 2025808:CCZ37_RS06215
uniprot id: A0A223MXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

2025808:CCZ37 RS01195
gene id: 2025808:CCZ37_RS01195
uniprot id: A0A223MUS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

2025808:CCZ37 RS10755
gene id: 2025808:CCZ37_RS10755
uniprot id: A0A223MZQ8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2025808:CCZ37 RS00080
gene id: 2025808:CCZ37_RS00080
uniprot id: A0A223MUA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

2025808:CCZ37 RS00310
gene id: 2025808:CCZ37_RS00310
uniprot id: A0A223MUB6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

2025808:CCZ37 RS08985
gene id: 2025808:CCZ37_RS08985
uniprot id: A0A223MYS4
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

2025808:CCZ37 RS07185
gene id: 2025808:CCZ37_RS07185
uniprot id: A0A223MXZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2025808:CCZ37 RS18680
gene id: 2025808:CCZ37_RS18680
uniprot id: A0A223N427
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS12200
gene id: 2025808:CCZ37_RS12200
uniprot id: A0A223N0J8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2025808:CCZ37 RS13225
gene id: 2025808:CCZ37_RS13225
uniprot id: A0A223N0V0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS11965
gene id: 2025808:CCZ37_RS11965
uniprot id: A0A223N0A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

2025808:CCZ37 RS06505
gene id: 2025808:CCZ37_RS06505
uniprot id: A0A223MXI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

2025808:CCZ37 RS12050
gene id: 2025808:CCZ37_RS12050
uniprot id: A0A223N0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2025808:CCZ37 RS10585
gene id: 2025808:CCZ37_RS10585
uniprot id: A0A223MZM4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2025808:CCZ37 RS00340
gene id: 2025808:CCZ37_RS00340
uniprot id: A0A223MUC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS02370
gene id: 2025808:CCZ37_RS02370
uniprot id: A0A223MVI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2025808:CCZ37 RS10570
gene id: 2025808:CCZ37_RS10570
uniprot id: A0A223MZM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

2025808:CCZ37 RS12875
gene id: 2025808:CCZ37_RS12875
uniprot id: A0A223N100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS09090
gene id: 2025808:CCZ37_RS09090
uniprot id: A0A223MYV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

2025808:CCZ37 RS12635
gene id: 2025808:CCZ37_RS12635
uniprot id: A0A223N0M1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS04520
gene id: 2025808:CCZ37_RS04520
uniprot id: A0A223MX40
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2025808:CCZ37 RS09495
gene id: 2025808:CCZ37_RS09495
uniprot id: A0A223MZ46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2025808:CCZ37 RS11675
gene id: 2025808:CCZ37_RS11675
uniprot id: A0A223N044
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS09795
gene id: 2025808:CCZ37_RS09795
uniprot id: A0A223MZ76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2025808:CCZ37 RS04095
gene id: 2025808:CCZ37_RS04095
uniprot id: A0A223MW74
names: Subcellular Location Annotation
messages: Cytoplasm

2025808:CCZ37 RS03580
gene id: 2025808:CCZ37_RS03580
uniprot id: A0A223MVZ2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2025808:CCZ37 RS11360
gene id: 2025808:CCZ37_RS11360
uniprot id: A0A223MZZ3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2025808:CCZ37 RS11480
gene id: 2025808:CCZ37_RS11480
uniprot id: A0A223N092
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2025808:CCZ37 RS03185
gene id: 2025808:CCZ37_RS03185
uniprot id: A0A223MVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

2025808:CCZ37 RS14170
gene id: 2025808:CCZ37_RS14170
uniprot id: A0A223N1W8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2025808:CCZ37 RS10310
gene id: 2025808:CCZ37_RS10310
uniprot id: A0A223MZG9
names: Similarity
messages: Belongs to the UPF0246 family.

2025808:CCZ37 RS02030
gene id: 2025808:CCZ37_RS02030
uniprot id: A0A223MV41
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

2025808:CCZ37 RS07525
gene id: 2025808:CCZ37_RS07525
uniprot id: A0A223MYM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

2025808:CCZ37 RS03400
gene id: 2025808:CCZ37_RS03400
uniprot id: A0A223MW12
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2025808:CCZ37 RS01025
gene id: 2025808:CCZ37_RS01025
uniprot id: A0A223MUT6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2025808:CCZ37 RS05565
gene id: 2025808:CCZ37_RS05565
uniprot id: A0A223MWW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS08765
gene id: 2025808:CCZ37_RS08765
uniprot id: A0A223MYN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2025808:CCZ37 RS08090
gene id: 2025808:CCZ37_RS08090
uniprot id: A0A223MYA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2025808:CCZ37 RS09630
gene id: 2025808:CCZ37_RS09630
uniprot id: A0A223MZL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2025808:CCZ37 RS00985
gene id: 2025808:CCZ37_RS00985
uniprot id: A0A223MUQ4
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

2025808:CCZ37 RS13410
gene id: 2025808:CCZ37_RS13410
uniprot id: A0A223N1K9
names: Subunit
messages: Monomer.

2025808:CCZ37 RS14090
gene id: 2025808:CCZ37_RS14090
uniprot id: A0A223N1T0
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS03650
gene id: 2025808:CCZ37_RS03650
uniprot id: A0A223MVX6
names: Similarity
messages: Belongs to the UPF0253 family.

2025808:CCZ37 RS01995
gene id: 2025808:CCZ37_RS01995
uniprot id: A0A223MV42
names: Similarity
messages: Belongs to the pyruvate kinase family.

2025808:CCZ37 RS02350
gene id: 2025808:CCZ37_RS02350
uniprot id: A0A223MVB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

2025808:CCZ37 RS09210
gene id: 2025808:CCZ37_RS09210
uniprot id: A0A223MYY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2025808:CCZ37 RS01090
gene id: 2025808:CCZ37_RS01090
uniprot id: A0A223MVE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

2025808:CCZ37 RS11210
gene id: 2025808:CCZ37_RS11210
uniprot id: A0A223MZW7
names: Similarity
messages: Belongs to the peptidase U62 family.

2025808:CCZ37 RS11440
gene id: 2025808:CCZ37_RS11440
uniprot id: A0A223N013
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2025808:CCZ37 RS09230
gene id: 2025808:CCZ37_RS09230
uniprot id: A0A223MYY5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

2025808:CCZ37 RS03240
gene id: 2025808:CCZ37_RS03240
uniprot id: A0A223MVQ2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2025808:CCZ37 RS11420
gene id: 2025808:CCZ37_RS11420
uniprot id: A0A223N008
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2025808:CCZ37 RS04310
gene id: 2025808:CCZ37_RS04310
uniprot id: A0A223MW82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2025808:CCZ37 RS10500
gene id: 2025808:CCZ37_RS10500
uniprot id: A0A223MZL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2025808:CCZ37 RS06585
gene id: 2025808:CCZ37_RS06585
uniprot id: A0A223MXH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2025808:CCZ37 RS11065
gene id: 2025808:CCZ37_RS11065
uniprot id: A0A223N021
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2025808:CCZ37 RS11340
gene id: 2025808:CCZ37_RS11340
uniprot id: A0A223MZZ9
names: Similarity
messages: Belongs to the DEAD box helicase family.

2025808:CCZ37 RS05595
gene id: 2025808:CCZ37_RS05595
uniprot id: A0A223MX14
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS03380
gene id: 2025808:CCZ37_RS03380
uniprot id: A0A223MVS4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2025808:CCZ37 RS17575
gene id: 2025808:CCZ37_RS17575
uniprot id: A0A223N3R6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2025808:CCZ37 RS11365
gene id: 2025808:CCZ37_RS11365
uniprot id: A0A223N056
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2025808:CCZ37 RS01860
gene id: 2025808:CCZ37_RS01860
uniprot id: A0A223MV70
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2025808:CCZ37 RS02385
gene id: 2025808:CCZ37_RS02385
uniprot id: A0A223MVF6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2025808:CCZ37 RS08975
gene id: 2025808:CCZ37_RS08975
uniprot id: A0A223MYU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

2025808:CCZ37 RS03080
gene id: 2025808:CCZ37_RS03080
uniprot id: A0A223MWB3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2025808:CCZ37 RS11405
gene id: 2025808:CCZ37_RS11405
uniprot id: A0A223N076
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2025808:CCZ37 RS04075
gene id: 2025808:CCZ37_RS04075
uniprot id: A0A223MW53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2025808:CCZ37 RS03205
gene id: 2025808:CCZ37_RS03205
uniprot id: A0A223MVP9
names: Similarity
messages: Belongs to the GppA/Ppx family.

2025808:CCZ37 RS02750
gene id: 2025808:CCZ37_RS02750
uniprot id: A0A223MVM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS09080
gene id: 2025808:CCZ37_RS09080
uniprot id: A0A223MYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS09075
gene id: 2025808:CCZ37_RS09075
uniprot id: A0A223MZ45
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2025808:CCZ37 RS11380
gene id: 2025808:CCZ37_RS11380
uniprot id: A0A223N073
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2025808:CCZ37 RS05950
gene id: 2025808:CCZ37_RS05950
uniprot id: A0A223MX75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2025808:CCZ37 RS12580
gene id: 2025808:CCZ37_RS12580
uniprot id: A0A223N0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS05085
gene id: 2025808:CCZ37_RS05085
uniprot id: A0A223MWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2025808:CCZ37 RS04265
gene id: 2025808:CCZ37_RS04265
uniprot id: A0A223MW81
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS06415
gene id: 2025808:CCZ37_RS06415
uniprot id: A0A223MXE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

2025808:CCZ37 RS04290
gene id: 2025808:CCZ37_RS04290
uniprot id: A0A223MX02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2025808:CCZ37 RS08290
gene id: 2025808:CCZ37_RS08290
uniprot id: A0A223MYG9
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

2025808:CCZ37 RS04175
gene id: 2025808:CCZ37_RS04175
uniprot id: A0A223MW67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

2025808:CCZ37 RS03550
gene id: 2025808:CCZ37_RS03550
uniprot id: A0A223MVW2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

2025808:CCZ37 RS11485
gene id: 2025808:CCZ37_RS11485
uniprot id: A0A223N018
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2025808:CCZ37 RS11595
gene id: 2025808:CCZ37_RS11595
uniprot id: A0A223N0B1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

2025808:CCZ37 RS03280
gene id: 2025808:CCZ37_RS03280
uniprot id: A0A223MVQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2025808:CCZ37 RS05785
gene id: 2025808:CCZ37_RS05785
uniprot id: A0A223MX32
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2025808:CCZ37 RS03215
gene id: 2025808:CCZ37_RS03215
uniprot id: A0A223MWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2025808:CCZ37 RS08040
gene id: 2025808:CCZ37_RS08040
uniprot id: A0A223MYA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS00990
gene id: 2025808:CCZ37_RS00990
uniprot id: A0A223MUM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

2025808:CCZ37 RS10870
gene id: 2025808:CCZ37_RS10870
uniprot id: A0A223MZS6
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

2025808:CCZ37 RS03980
gene id: 2025808:CCZ37_RS03980
uniprot id: A0A223MW99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS08725
gene id: 2025808:CCZ37_RS08725
uniprot id: A0A223MYN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

2025808:CCZ37 RS06060
gene id: 2025808:CCZ37_RS06060
uniprot id: A0A223MX92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS18310
gene id: 2025808:CCZ37_RS18310
uniprot id: A0A223N425
names: Similarity
messages: Belongs to the DEAD box helicase family.

2025808:CCZ37 RS10025
gene id: 2025808:CCZ37_RS10025
uniprot id: A0A223MZB3
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

2025808:CCZ37 RS02840
gene id: 2025808:CCZ37_RS02840
uniprot id: A0A223MVL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2025808:CCZ37 RS07100
gene id: 2025808:CCZ37_RS07100
uniprot id: A0A223MYE6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

2025808:CCZ37 RS13275
gene id: 2025808:CCZ37_RS13275
uniprot id: A0A223N0V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2025808:CCZ37 RS05330
gene id: 2025808:CCZ37_RS05330
uniprot id: A0A223MWW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

2025808:CCZ37 RS18455
gene id: 2025808:CCZ37_RS18455
uniprot id: A0A223N3P9
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS15200
gene id: 2025808:CCZ37_RS15200
uniprot id: A0A223N259
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

2025808:CCZ37 RS10635
gene id: 2025808:CCZ37_RS10635
uniprot id: A0A223MZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

2025808:CCZ37 RS00020
gene id: 2025808:CCZ37_RS00020
uniprot id: A0A223MU61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2025808:CCZ37 RS11495
gene id: 2025808:CCZ37_RS11495
uniprot id: A0A223N086
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2025808:CCZ37 RS11390
gene id: 2025808:CCZ37_RS11390
uniprot id: A0A223N006
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2025808:CCZ37 RS11085
gene id: 2025808:CCZ37_RS11085
uniprot id: A0A223MZV2
names: Similarity
messages: Belongs to the PhoH family.

2025808:CCZ37 RS15225
gene id: 2025808:CCZ37_RS15225
uniprot id: A0A223N2K8
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

2025808:CCZ37 RS11140
gene id: 2025808:CCZ37_RS11140
uniprot id: A0A223MZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2025808:CCZ37 RS11410
gene id: 2025808:CCZ37_RS11410
uniprot id: A0A223N005
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2025808:CCZ37 RS11835
gene id: 2025808:CCZ37_RS11835
uniprot id: A0A223N074
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

2025808:CCZ37 RS00100
gene id: 2025808:CCZ37_RS00100
uniprot id: A0A223MU86
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2025808:CCZ37 RS09255
gene id: 2025808:CCZ37_RS09255
uniprot id: A0A223MYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS17870
gene id: 2025808:CCZ37_RS17870
uniprot id: A0A223N330
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS04000
gene id: 2025808:CCZ37_RS04000
uniprot id: A0A223MW26
names: Similarity
messages: Belongs to the UPF0250 family.

2025808:CCZ37 RS04105
gene id: 2025808:CCZ37_RS04105
uniprot id: A0A223MWA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

2025808:CCZ37 RS01825
gene id: 2025808:CCZ37_RS01825
uniprot id: A0A223MVP5
names: Similarity
messages: Belongs to the UPF0235 family.

2025808:CCZ37 RS01260
gene id: 2025808:CCZ37_RS01260
uniprot id: A0A223MUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2025808:CCZ37 RS06280
gene id: 2025808:CCZ37_RS06280
uniprot id: A0A223MXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

2025808:CCZ37 RS10435
gene id: 2025808:CCZ37_RS10435
uniprot id: A0A223MZJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS12640
gene id: 2025808:CCZ37_RS12640
uniprot id: A0A223N0Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

2025808:CCZ37 RS04220
gene id: 2025808:CCZ37_RS04220
uniprot id: A0A223MWG1
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS01210
gene id: 2025808:CCZ37_RS01210
uniprot id: A0A223MUQ1
names: Similarity
messages: Belongs to the SlyX family.

2025808:CCZ37 RS02895
gene id: 2025808:CCZ37_RS02895
uniprot id: A0A223MVJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS11980
gene id: 2025808:CCZ37_RS11980
uniprot id: A0A223N0N7
names: Subcellular Location Annotation
messages: Membrane

2025808:CCZ37 RS18785
gene id: 2025808:CCZ37_RS18785
uniprot id: A0A223N1K9
names: Subunit
messages: Monomer.

2025808:CCZ37 RS09880
gene id: 2025808:CCZ37_RS09880
uniprot id: A0A223MZ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the skp family.
messages: Homotrimer.
messages: Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
messages: Periplasm

2025808:CCZ37 RS11860
gene id: 2025808:CCZ37_RS11860
uniprot id: A0A223N080
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2025808:CCZ37 RS08430
gene id: 2025808:CCZ37_RS08430
uniprot id: A0A223MZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

2025808:CCZ37 RS17585
gene id: 2025808:CCZ37_RS17585
uniprot id: A0A223N3A5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS09780
gene id: 2025808:CCZ37_RS09780
uniprot id: A0A223MZ80
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2025808:CCZ37 RS13700
gene id: 2025808:CCZ37_RS13700
uniprot id: A0A223N3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

2025808:CCZ37 RS01900
gene id: 2025808:CCZ37_RS01900
uniprot id: A0A223MV34
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2025808:CCZ37 RS08485
gene id: 2025808:CCZ37_RS08485
uniprot id: A0A223MYI0
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

2025808:CCZ37 RS10600
gene id: 2025808:CCZ37_RS10600
uniprot id: A0A223MZM6
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2025808:CCZ37 RS04720
gene id: 2025808:CCZ37_RS04720
uniprot id: A0A223MWQ5
names: Similarity
messages: Belongs to the UPF0227 family.

2025808:CCZ37 RS01630
gene id: 2025808:CCZ37_RS01630
uniprot id: A0A223MUX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2025808:CCZ37 RS12785
gene id: 2025808:CCZ37_RS12785
uniprot id: A0A223N0P1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2025808:CCZ37 RS02220
gene id: 2025808:CCZ37_RS02220
uniprot id: A0A223MV66
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2025808:CCZ37 RS11470
gene id: 2025808:CCZ37_RS11470
uniprot id: A0A223N016
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2025808:CCZ37 RS13895
gene id: 2025808:CCZ37_RS13895
uniprot id: A0A223N1F5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

2025808:CCZ37 RS09860
gene id: 2025808:CCZ37_RS09860
uniprot id: A0A223MZ99
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2025808:CCZ37 RS13985
gene id: 2025808:CCZ37_RS13985
uniprot id: A0A223N1E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

2025808:CCZ37 RS08370
gene id: 2025808:CCZ37_RS08370
uniprot id: A0A223MYZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS13020
gene id: 2025808:CCZ37_RS13020
uniprot id: A0A223N0Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2025808:CCZ37 RS09625
gene id: 2025808:CCZ37_RS09625
uniprot id: A0A223MZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

2025808:CCZ37 RS11175
gene id: 2025808:CCZ37_RS11175
uniprot id: A0A223MZW6
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2025808:CCZ37 RS08635
gene id: 2025808:CCZ37_RS08635
uniprot id: A0A223MYX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS07685
gene id: 2025808:CCZ37_RS07685
uniprot id: A0A223MY27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

2025808:CCZ37 RS15690
gene id: 2025808:CCZ37_RS15690
uniprot id: A0A223N2S1
names: Similarity
messages: Belongs to the SUI1 family.

2025808:CCZ37 RS01020
gene id: 2025808:CCZ37_RS01020
uniprot id: A0A223N0X3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2025808:CCZ37 RS05470
gene id: 2025808:CCZ37_RS05470
uniprot id: A0A223MWW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

2025808:CCZ37 RS15285
gene id: 2025808:CCZ37_RS15285
uniprot id: A0A223N1Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

2025808:CCZ37 RS01035
gene id: 2025808:CCZ37_RS01035
uniprot id: A0A223MUT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2025808:CCZ37 RS03110
gene id: 2025808:CCZ37_RS03110
uniprot id: A0A223MVX8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

2025808:CCZ37 RS08125
gene id: 2025808:CCZ37_RS08125
uniprot id: A0A223MYB9
names: Similarity
messages: Belongs to the DEAD box helicase family.

2025808:CCZ37 RS09620
gene id: 2025808:CCZ37_RS09620
uniprot id: A0A223MZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

2025808:CCZ37 RS11200
gene id: 2025808:CCZ37_RS11200
uniprot id: A0A223N0A7
names: Subcellular Location Annotation
messages: Cytoplasm

2025808:CCZ37 RS00195
gene id: 2025808:CCZ37_RS00195
uniprot id: A0A223MUH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

2025808:CCZ37 RS10615
gene id: 2025808:CCZ37_RS10615
uniprot id: A0A223MZM2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2025808:CCZ37 RS10070
gene id: 2025808:CCZ37_RS10070
uniprot id: A0A223MZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2025808:CCZ37 RS11105
gene id: 2025808:CCZ37_RS11105
uniprot id: A0A223MZW1
names: Similarity
messages: Belongs to the RutC family.

2025808:CCZ37 RS10820
gene id: 2025808:CCZ37_RS10820
uniprot id: A0A223MZR5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2025808:CCZ37 RS14270
gene id: 2025808:CCZ37_RS14270
uniprot id: A0A223N1J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

2025808:CCZ37 RS01185
gene id: 2025808:CCZ37_RS01185
uniprot id: A0A223MVF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2025808:CCZ37 RS11425
gene id: 2025808:CCZ37_RS11425
uniprot id: A0A223N009
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2025808:CCZ37 RS01105
gene id: 2025808:CCZ37_RS01105
uniprot id: A0A223MUN8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

2025808:CCZ37 RS02185
gene id: 2025808:CCZ37_RS02185
uniprot id: A0A223MV71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

2025808:CCZ37 RS12945
gene id: 2025808:CCZ37_RS12945
uniprot id: A0A223N131
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

2025808:CCZ37 RS00390
gene id: 2025808:CCZ37_RS00390
uniprot id: A0A223N199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS03655
gene id: 2025808:CCZ37_RS03655
uniprot id: A0A223MW17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS03775
gene id: 2025808:CCZ37_RS03775
uniprot id: A0A223MVZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

2025808:CCZ37 RS10775
gene id: 2025808:CCZ37_RS10775
uniprot id: A0A223MZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

2025808:CCZ37 RS08925
gene id: 2025808:CCZ37_RS08925
uniprot id: A0A223MYR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2025808:CCZ37 RS13295
gene id: 2025808:CCZ37_RS13295
uniprot id: A0A223N167
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

2025808:CCZ37 RS09275
gene id: 2025808:CCZ37_RS09275
uniprot id: A0A223MZ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

2025808:CCZ37 RS04225
gene id: 2025808:CCZ37_RS04225
uniprot id: A0A223MW77
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2025808:CCZ37 RS11685
gene id: 2025808:CCZ37_RS11685
uniprot id: A0A223N049
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2025808:CCZ37 RS01960
gene id: 2025808:CCZ37_RS01960
uniprot id: A0A223MV17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2025808:CCZ37 RS01865
gene id: 2025808:CCZ37_RS01865
uniprot id: A0A223MV11
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

2025808:CCZ37 RS00335
gene id: 2025808:CCZ37_RS00335
uniprot id: A0A223MV28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS10005
gene id: 2025808:CCZ37_RS10005
uniprot id: A0A223MZA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

2025808:CCZ37 RS08990
gene id: 2025808:CCZ37_RS08990
uniprot id: A0A223MZA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2025808:CCZ37 RS10150
gene id: 2025808:CCZ37_RS10150
uniprot id: A0A223MZE6
names: Similarity
messages: Belongs to the SufE family.

2025808:CCZ37 RS09910
gene id: 2025808:CCZ37_RS09910
uniprot id: A0A223MZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2025808:CCZ37 RS01520
gene id: 2025808:CCZ37_RS01520
uniprot id: A0A223MUW8
names: Similarity
messages: Belongs to the GSP E family.

2025808:CCZ37 RS02635
gene id: 2025808:CCZ37_RS02635
uniprot id: A0A223MVL4
names: Similarity
messages: Belongs to the P(II) protein family.

2025808:CCZ37 RS05410
gene id: 2025808:CCZ37_RS05410
uniprot id: A0A223MX10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

2025808:CCZ37 RS04015
gene id: 2025808:CCZ37_RS04015
uniprot id: A0A223MWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

2025808:CCZ37 RS06925
gene id: 2025808:CCZ37_RS06925
uniprot id: A0A223MXN0
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

2025808:CCZ37 RS04970
gene id: 2025808:CCZ37_RS04970
uniprot id: A0A223MWQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

2025808:CCZ37 RS09380
gene id: 2025808:CCZ37_RS09380
uniprot id: A0A223MZ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2025808:CCZ37 RS09280
gene id: 2025808:CCZ37_RS09280
uniprot id: A0A223MYZ4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2025808:CCZ37 RS10620
gene id: 2025808:CCZ37_RS10620
uniprot id: A0A223MZX1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2025808:CCZ37 RS00365
gene id: 2025808:CCZ37_RS00365
uniprot id: A0A223MUJ7
names: Similarity
messages: Belongs to the HSP15 family.

2025808:CCZ37 RS02425
gene id: 2025808:CCZ37_RS02425
uniprot id: A0A223MVG7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

2025808:CCZ37 RS14660
gene id: 2025808:CCZ37_RS14660
uniprot id: A0A223N1S6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2025808:CCZ37 RS12795
gene id: 2025808:CCZ37_RS12795
uniprot id: A0A223N108
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

2025808:CCZ37 RS01050
gene id: 2025808:CCZ37_RS01050
uniprot id: A0A223MUQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2025808:CCZ37 RS07040
gene id: 2025808:CCZ37_RS07040
uniprot id: A0A223MXQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

2025808:CCZ37 RS04200
gene id: 2025808:CCZ37_RS04200
uniprot id: A0A223MW59
names: Similarity
messages: Belongs to the asparagine synthetase family.

2025808:CCZ37 RS13520
gene id: 2025808:CCZ37_RS13520
uniprot id: A0A223N1C7
names: Subcellular Location Annotation
messages: Cell inner membrane

2025808:CCZ37 RS01605
gene id: 2025808:CCZ37_RS01605
uniprot id: A0A223MUW1
names: Similarity
messages: Belongs to the peptidase U62 family.

2025808:CCZ37 RS00395
gene id: 2025808:CCZ37_RS00395
uniprot id: A0A223MUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

2025808:CCZ37 RS05245
gene id: 2025808:CCZ37_RS05245
uniprot id: A0A223MWR0
names: Similarity
messages: Belongs to the elongation factor P family.

2025808:CCZ37 RS01650
gene id: 2025808:CCZ37_RS01650
uniprot id: A0A223MUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2025808:CCZ37 RS11165
gene id: 2025808:CCZ37_RS11165
uniprot id: A0A223MZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2025808:CCZ37 RS10535
gene id: 2025808:CCZ37_RS10535
uniprot id: A0A223MZL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2025808:CCZ37 RS00380
gene id: 2025808:CCZ37_RS00380
uniprot id: A0A223MUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

2025808:CCZ37 RS00105
gene id: 2025808:CCZ37_RS00105
uniprot id: A0A223MUF1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

2025808:CCZ37 RS14580
gene id: 2025808:CCZ37_RS14580
uniprot id: A0A223N2A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2025808:CCZ37 RS00695
gene id: 2025808:CCZ37_RS00695
uniprot id: A0A223MUK5
names: Similarity
messages: Belongs to the Dps family.