2024526:LXD69 RS10495
gene id: 2024526:LXD69_RS10495
uniprot id: A0A8T9UGU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS03950
gene id: 2024526:LXD69_RS03950
uniprot id: A0A8T9U9C0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS17950
gene id: 2024526:LXD69_RS17950
uniprot id: A0A8T9UCJ5
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS17840
gene id: 2024526:LXD69_RS17840
uniprot id: A0A8T9U9J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2024526:LXD69 RS03290
gene id: 2024526:LXD69_RS03290
uniprot id: A0A8T9UF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2024526:LXD69 RS03765
gene id: 2024526:LXD69_RS03765
uniprot id: A0A8T9UE86
names: Similarity
messages: Belongs to the thioredoxin family.

2024526:LXD69 RS01420
gene id: 2024526:LXD69_RS01420
uniprot id: A0A8T9UBE5
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS15875
gene id: 2024526:LXD69_RS15875
uniprot id: A0A8T9U716
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

2024526:LXD69 RS14390
gene id: 2024526:LXD69_RS14390
uniprot id: A0A8T9UC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2024526:LXD69 RS17175
gene id: 2024526:LXD69_RS17175
uniprot id: A0A8T9UDC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

2024526:LXD69 RS04060
gene id: 2024526:LXD69_RS04060
uniprot id: A0A8T9UCS2
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS12595
gene id: 2024526:LXD69_RS12595
uniprot id: A0A8T9UB16
names: Similarity
messages: Belongs to the RutC family.

2024526:LXD69 RS05600
gene id: 2024526:LXD69_RS05600
uniprot id: A0A8T9UEK7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2024526:LXD69 RS12860
gene id: 2024526:LXD69_RS12860
uniprot id: A0A8T9U4N2
names: Similarity
messages: Belongs to the Dps family.

2024526:LXD69 RS15625
gene id: 2024526:LXD69_RS15625
uniprot id: A0A8T9U9K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

2024526:LXD69 RS12880
gene id: 2024526:LXD69_RS12880
uniprot id: A0A8T9U5T6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

2024526:LXD69 RS12575
gene id: 2024526:LXD69_RS12575
uniprot id: A0A8T9U5L4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

2024526:LXD69 RS08060
gene id: 2024526:LXD69_RS08060
uniprot id: A0A8T9UG35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

2024526:LXD69 RS16540
gene id: 2024526:LXD69_RS16540
uniprot id: A0A8T9UBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS17150
gene id: 2024526:LXD69_RS17150
uniprot id: A0A8T9U7S5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2024526:LXD69 RS03865
gene id: 2024526:LXD69_RS03865
uniprot id: A0A8T9UF11
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS03225
gene id: 2024526:LXD69_RS03225
uniprot id: A0A8T9UBK6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS06110
gene id: 2024526:LXD69_RS06110
uniprot id: A0A8T9UFI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2024526:LXD69 RS06100
gene id: 2024526:LXD69_RS06100
uniprot id: A0A8T9UD49
names: Similarity
messages: Belongs to the pyruvate kinase family.

2024526:LXD69 RS07750
gene id: 2024526:LXD69_RS07750
uniprot id: A0A8T9UGK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2024526:LXD69 RS09295
gene id: 2024526:LXD69_RS09295
uniprot id: A0A8T9U3P2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2024526:LXD69 RS06645
gene id: 2024526:LXD69_RS06645
uniprot id: A0A8T9UCP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2024526:LXD69 RS00050
gene id: 2024526:LXD69_RS00050
uniprot id: A0A8T9UDS1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2024526:LXD69 RS08580
gene id: 2024526:LXD69_RS08580
uniprot id: A0A8T9UEX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2024526:LXD69 RS10425
gene id: 2024526:LXD69_RS10425
uniprot id: A0A8T9U6I9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2024526:LXD69 RS02170
gene id: 2024526:LXD69_RS02170
uniprot id: A0A8T9UEQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2024526:LXD69 RS08035
gene id: 2024526:LXD69_RS08035
uniprot id: A0A8T9UDC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

2024526:LXD69 RS13230
gene id: 2024526:LXD69_RS13230
uniprot id: A0A8T9U7Z9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2024526:LXD69 RS12235
gene id: 2024526:LXD69_RS12235
uniprot id: A0A8T9U986
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2024526:LXD69 RS16805
gene id: 2024526:LXD69_RS16805
uniprot id: A0A8T9U8Y5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2024526:LXD69 RS07550
gene id: 2024526:LXD69_RS07550
uniprot id: A0A8T9UFB9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2024526:LXD69 RS06665
gene id: 2024526:LXD69_RS06665
uniprot id: A0A8T9UGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2024526:LXD69 RS17540
gene id: 2024526:LXD69_RS17540
uniprot id: A0A8T9UBU8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2024526:LXD69 RS16515
gene id: 2024526:LXD69_RS16515
uniprot id: A0A8T9U6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

2024526:LXD69 RS01325
gene id: 2024526:LXD69_RS01325
uniprot id: A0A8T9U8Z6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2024526:LXD69 RS07675
gene id: 2024526:LXD69_RS07675
uniprot id: A0A8T9UFT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

2024526:LXD69 RS14605
gene id: 2024526:LXD69_RS14605
uniprot id: A0A8T9U5L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

2024526:LXD69 RS04055
gene id: 2024526:LXD69_RS04055
uniprot id: A0A8T9UDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS03790
gene id: 2024526:LXD69_RS03790
uniprot id: A0A8T9U996
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

2024526:LXD69 RS01155
gene id: 2024526:LXD69_RS01155
uniprot id: A0A8T9U7W6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2024526:LXD69 RS16255
gene id: 2024526:LXD69_RS16255
uniprot id: A0A8T9UBI2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2024526:LXD69 RS02495
gene id: 2024526:LXD69_RS02495
uniprot id: A0A8T9UDX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2024526:LXD69 RS00380
gene id: 2024526:LXD69_RS00380
uniprot id: A0A8T9U8G4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

2024526:LXD69 RS01450
gene id: 2024526:LXD69_RS01450
uniprot id: A0A8T9UEF9
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS01005
gene id: 2024526:LXD69_RS01005
uniprot id: A0A8T9U7T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2024526:LXD69 RS14570
gene id: 2024526:LXD69_RS14570
uniprot id: A0A8T9U6E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2024526:LXD69 RS10525
gene id: 2024526:LXD69_RS10525
uniprot id: A0A8T9U8F0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

2024526:LXD69 RS17870
gene id: 2024526:LXD69_RS17870
uniprot id: A0A8T9U867
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2024526:LXD69 RS10365
gene id: 2024526:LXD69_RS10365
uniprot id: A0A8T9U3B7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2024526:LXD69 RS00330
gene id: 2024526:LXD69_RS00330
uniprot id: A0A8T9U938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2024526:LXD69 RS00690
gene id: 2024526:LXD69_RS00690
uniprot id: A0A8T9UCZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2024526:LXD69 RS16025
gene id: 2024526:LXD69_RS16025
uniprot id: A0A8T9U741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2024526:LXD69 RS00125
gene id: 2024526:LXD69_RS00125
uniprot id: A0A8T9U8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2024526:LXD69 RS01055
gene id: 2024526:LXD69_RS01055
uniprot id: A0A8T9U7U2
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS04345
gene id: 2024526:LXD69_RS04345
uniprot id: A0A8T9UEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2024526:LXD69 RS00860
gene id: 2024526:LXD69_RS00860
uniprot id: A0A8T9UB28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2024526:LXD69 RS16825
gene id: 2024526:LXD69_RS16825
uniprot id: A0A8T9U6P1
names: Similarity
messages: Belongs to the threonine aldolase family.

2024526:LXD69 RS00920
gene id: 2024526:LXD69_RS00920
uniprot id: A0A8T9U9F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2024526:LXD69 RS12360
gene id: 2024526:LXD69_RS12360
uniprot id: A0A8T9U9A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

2024526:LXD69 RS09280
gene id: 2024526:LXD69_RS09280
uniprot id: A0A8T9U7U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2024526:LXD69 RS00685
gene id: 2024526:LXD69_RS00685
uniprot id: A0A8T9UE26
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2024526:LXD69 RS15105
gene id: 2024526:LXD69_RS15105
uniprot id: A0A8T9U6N5
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS15800
gene id: 2024526:LXD69_RS15800
uniprot id: A0A8T9UB84
names: Subcellular Location Annotation
messages: Cytoplasm

2024526:LXD69 RS15840
gene id: 2024526:LXD69_RS15840
uniprot id: A0A8T9U9P4
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS09790
gene id: 2024526:LXD69_RS09790
uniprot id: A0A8T9U9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

2024526:LXD69 RS06690
gene id: 2024526:LXD69_RS06690
uniprot id: A0A8T9UE24
names: Similarity
messages: Belongs to the asparaginase 1 family.

2024526:LXD69 RS00880
gene id: 2024526:LXD69_RS00880
uniprot id: A0A8T9UBG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2024526:LXD69 RS14575
gene id: 2024526:LXD69_RS14575
uniprot id: A0A8T9U6W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2024526:LXD69 RS12190
gene id: 2024526:LXD69_RS12190
uniprot id: A0A8T9U7H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS06775
gene id: 2024526:LXD69_RS06775
uniprot id: A0A8T9UFQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2024526:LXD69 RS02200
gene id: 2024526:LXD69_RS02200
uniprot id: A0A8T9UA76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS17805
gene id: 2024526:LXD69_RS17805
uniprot id: A0A8T9U772
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

2024526:LXD69 RS16790
gene id: 2024526:LXD69_RS16790
uniprot id: A0A8T9U865
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2024526:LXD69 RS16220
gene id: 2024526:LXD69_RS16220
uniprot id: A0A8T9U9L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2024526:LXD69 RS00130
gene id: 2024526:LXD69_RS00130
uniprot id: A0A8T9U8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

2024526:LXD69 RS03220
gene id: 2024526:LXD69_RS03220
uniprot id: A0A8T9UCP0
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS13210
gene id: 2024526:LXD69_RS13210
uniprot id: A0A8T9UBD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2024526:LXD69 RS06625
gene id: 2024526:LXD69_RS06625
uniprot id: A0A8T9UAT4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2024526:LXD69 RS13125
gene id: 2024526:LXD69_RS13125
uniprot id: A0A8T9U9P1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2024526:LXD69 RS00875
gene id: 2024526:LXD69_RS00875
uniprot id: A0A8T9UCU4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2024526:LXD69 RS11065
gene id: 2024526:LXD69_RS11065
uniprot id: A0A8T9UAA1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2024526:LXD69 RS10540
gene id: 2024526:LXD69_RS10540
uniprot id: A0A8T9U4E6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2024526:LXD69 RS03660
gene id: 2024526:LXD69_RS03660
uniprot id: A0A8T9UBT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2024526:LXD69 RS14190
gene id: 2024526:LXD69_RS14190
uniprot id: A0A8T9UBW4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

2024526:LXD69 RS00810
gene id: 2024526:LXD69_RS00810
uniprot id: A0A8T9UB20
names: Similarity
messages: Belongs to the citrate synthase family.

2024526:LXD69 RS06325
gene id: 2024526:LXD69_RS06325
uniprot id: A0A8T9UEV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2024526:LXD69 RS06800
gene id: 2024526:LXD69_RS06800
uniprot id: A0A8T9UCS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS01275
gene id: 2024526:LXD69_RS01275
uniprot id: A0A8T9U9M7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2024526:LXD69 RS00995
gene id: 2024526:LXD69_RS00995
uniprot id: A0A8T9UE83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2024526:LXD69 RS01130
gene id: 2024526:LXD69_RS01130
uniprot id: A0A8T9UCZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2024526:LXD69 RS15085
gene id: 2024526:LXD69_RS15085
uniprot id: A0A8T9UAV0
names: Similarity
messages: Belongs to the TrpC family.

2024526:LXD69 RS04985
gene id: 2024526:LXD69_RS04985
uniprot id: A0A8T9UD86
names: Similarity
messages: Belongs to the peptidase S8 family.

2024526:LXD69 RS09400
gene id: 2024526:LXD69_RS09400
uniprot id: A0A8T9U7P6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

2024526:LXD69 RS15350
gene id: 2024526:LXD69_RS15350
uniprot id: A0A8T9UCG7
names: Similarity
messages: Belongs to the peptidase C40 family.

2024526:LXD69 RS06120
gene id: 2024526:LXD69_RS06120
uniprot id: A0A8T9UES6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2024526:LXD69 RS00965
gene id: 2024526:LXD69_RS00965
uniprot id: A0A8T9UB47
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2024526:LXD69 RS10285
gene id: 2024526:LXD69_RS10285
uniprot id: A0A8T9U864
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2024526:LXD69 RS07760
gene id: 2024526:LXD69_RS07760
uniprot id: A0A8T9UBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

2024526:LXD69 RS02235
gene id: 2024526:LXD69_RS02235
uniprot id: A0A8T9UD69
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

2024526:LXD69 RS17485
gene id: 2024526:LXD69_RS17485
uniprot id: A0A8T9U714
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2024526:LXD69 RS14060
gene id: 2024526:LXD69_RS14060
uniprot id: A0A8T9U6J3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS05395
gene id: 2024526:LXD69_RS05395
uniprot id: A0A8T9UDF4
names: Similarity
messages: Belongs to the GARS family.

2024526:LXD69 RS00960
gene id: 2024526:LXD69_RS00960
uniprot id: A0A8T9UCK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2024526:LXD69 RS11005
gene id: 2024526:LXD69_RS11005
uniprot id: A0A8T9U6U4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2024526:LXD69 RS13655
gene id: 2024526:LXD69_RS13655
uniprot id: A0A8T9UA11
names: Similarity
messages: Belongs to the UPF0246 family.

2024526:LXD69 RS06380
gene id: 2024526:LXD69_RS06380
uniprot id: A0A8T9UDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2024526:LXD69 RS03020
gene id: 2024526:LXD69_RS03020
uniprot id: A0A8T9UCK4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

2024526:LXD69 RS00515
gene id: 2024526:LXD69_RS00515
uniprot id: A0A8T9UDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

2024526:LXD69 RS15915
gene id: 2024526:LXD69_RS15915
uniprot id: A0A8T9UB13
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS07015
gene id: 2024526:LXD69_RS07015
uniprot id: A0A8T9UEI8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2024526:LXD69 RS13110
gene id: 2024526:LXD69_RS13110
uniprot id: A0A8T9UBC0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2024526:LXD69 RS14150
gene id: 2024526:LXD69_RS14150
uniprot id: A0A8T9U8H1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2024526:LXD69 RS00430
gene id: 2024526:LXD69_RS00430
uniprot id: A0A8T9UAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

2024526:LXD69 RS00975
gene id: 2024526:LXD69_RS00975
uniprot id: A0A8T9U9G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2024526:LXD69 RS05225
gene id: 2024526:LXD69_RS05225
uniprot id: A0A8T9UA24
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2024526:LXD69 RS10510
gene id: 2024526:LXD69_RS10510
uniprot id: A0A8T9UA06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2024526:LXD69 RS10330
gene id: 2024526:LXD69_RS10330
uniprot id: A0A8T9U4A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2024526:LXD69 RS12230
gene id: 2024526:LXD69_RS12230
uniprot id: A0A8T9U4B9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2024526:LXD69 RS10585
gene id: 2024526:LXD69_RS10585
uniprot id: A0A8T9U423
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2024526:LXD69 RS10355
gene id: 2024526:LXD69_RS10355
uniprot id: A0A8T9U9X6
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS04970
gene id: 2024526:LXD69_RS04970
uniprot id: A0A8T9UF35
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2024526:LXD69 RS03900
gene id: 2024526:LXD69_RS03900
uniprot id: A0A8T9U9B4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2024526:LXD69 RS11210
gene id: 2024526:LXD69_RS11210
uniprot id: A0A8T9U5J5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

2024526:LXD69 RS07685
gene id: 2024526:LXD69_RS07685
uniprot id: A0A8T9UDZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2024526:LXD69 RS09265
gene id: 2024526:LXD69_RS09265
uniprot id: A0A8T9U9D3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2024526:LXD69 RS06480
gene id: 2024526:LXD69_RS06480
uniprot id: A0A8T9UDY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2024526:LXD69 RS11195
gene id: 2024526:LXD69_RS11195
uniprot id: A0A8T9U4T3
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS14185
gene id: 2024526:LXD69_RS14185
uniprot id: A0A8T9U7D5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

2024526:LXD69 RS03635
gene id: 2024526:LXD69_RS03635
uniprot id: A0A8T9UCI9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2024526:LXD69 RS03960
gene id: 2024526:LXD69_RS03960
uniprot id: A0A8T9UCQ4
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS00950
gene id: 2024526:LXD69_RS00950
uniprot id: A0A8T9UD43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2024526:LXD69 RS07095
gene id: 2024526:LXD69_RS07095
uniprot id: A0A8T9UEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

2024526:LXD69 RS04415
gene id: 2024526:LXD69_RS04415
uniprot id: A0A8T9UET1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2024526:LXD69 RS06460
gene id: 2024526:LXD69_RS06460
uniprot id: A0A8T9UG93
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

2024526:LXD69 RS14920
gene id: 2024526:LXD69_RS14920
uniprot id: A0A8T9U983
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2024526:LXD69 RS05515
gene id: 2024526:LXD69_RS05515
uniprot id: A0A8T9UF07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

2024526:LXD69 RS12310
gene id: 2024526:LXD69_RS12310
uniprot id: A0A8T9U990
names: Similarity
messages: Belongs to the Fur family.

2024526:LXD69 RS15620
gene id: 2024526:LXD69_RS15620
uniprot id: A0A8T9UB19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

2024526:LXD69 RS05615
gene id: 2024526:LXD69_RS05615
uniprot id: A0A8T9UC45
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS07630
gene id: 2024526:LXD69_RS07630
uniprot id: A0A8T9UES9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

2024526:LXD69 RS09220
gene id: 2024526:LXD69_RS09220
uniprot id: A0A8T9U3B3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2024526:LXD69 RS17580
gene id: 2024526:LXD69_RS17580
uniprot id: A0A8T9UCC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2024526:LXD69 RS00425
gene id: 2024526:LXD69_RS00425
uniprot id: A0A8T9UEK4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

2024526:LXD69 RS01655
gene id: 2024526:LXD69_RS01655
uniprot id: A0A8T9UEI7
names: Similarity
messages: Belongs to the ArsC family.

2024526:LXD69 RS00940
gene id: 2024526:LXD69_RS00940
uniprot id: A0A8T9UA71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2024526:LXD69 RS14845
gene id: 2024526:LXD69_RS14845
uniprot id: A0A8T9U6I5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2024526:LXD69 RS09755
gene id: 2024526:LXD69_RS09755
uniprot id: A0A8T9U818
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2024526:LXD69 RS17115
gene id: 2024526:LXD69_RS17115
uniprot id: A0A8T9U939
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS07545
gene id: 2024526:LXD69_RS07545
uniprot id: A0A8T9UBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2024526:LXD69 RS08325
gene id: 2024526:LXD69_RS08325
uniprot id: A0A8T9UET7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2024526:LXD69 RS11850
gene id: 2024526:LXD69_RS11850
uniprot id: A0A8T9U8W9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

2024526:LXD69 RS08885
gene id: 2024526:LXD69_RS08885
uniprot id: A0A8T9U459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2024526:LXD69 RS01895
gene id: 2024526:LXD69_RS01895
uniprot id: A0A8T9UC22
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

2024526:LXD69 RS06125
gene id: 2024526:LXD69_RS06125
uniprot id: A0A8T9UDT1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS10620
gene id: 2024526:LXD69_RS10620
uniprot id: A0A8T9U3G7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2024526:LXD69 RS05640
gene id: 2024526:LXD69_RS05640
uniprot id: A0A8T9UFD6
names: Similarity
messages: Belongs to the SCO1/2 family.

2024526:LXD69 RS04450
gene id: 2024526:LXD69_RS04450
uniprot id: A0A8T9UDA8
names: Similarity
messages: Belongs to the ArsC family.

2024526:LXD69 RS10925
gene id: 2024526:LXD69_RS10925
uniprot id: A0A8T9U5D5
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS03940
gene id: 2024526:LXD69_RS03940
uniprot id: A0A8T9UFE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2024526:LXD69 RS07680
gene id: 2024526:LXD69_RS07680
uniprot id: A0A8T9UET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

2024526:LXD69 RS01035
gene id: 2024526:LXD69_RS01035
uniprot id: A0A8T9UBI9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

2024526:LXD69 RS17615
gene id: 2024526:LXD69_RS17615
uniprot id: A0A8T9U8N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

2024526:LXD69 RS01455
gene id: 2024526:LXD69_RS01455
uniprot id: A0A8T9UDE3
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS01190
gene id: 2024526:LXD69_RS01190
uniprot id: A0A8T9UAD0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2024526:LXD69 RS09370
gene id: 2024526:LXD69_RS09370
uniprot id: A0A8T9U7H3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2024526:LXD69 RS16135
gene id: 2024526:LXD69_RS16135
uniprot id: A0A8T9UBB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2024526:LXD69 RS14115
gene id: 2024526:LXD69_RS14115
uniprot id: A0A8T9UAA4
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS04595
gene id: 2024526:LXD69_RS04595
uniprot id: A0A8T9UEM1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

2024526:LXD69 RS15100
gene id: 2024526:LXD69_RS15100
uniprot id: A0A8T9U902
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

2024526:LXD69 RS13105
gene id: 2024526:LXD69_RS13105
uniprot id: A0A8T9U6P5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS05175
gene id: 2024526:LXD69_RS05175
uniprot id: A0A8T9UA14
names: Similarity
messages: Belongs to the Skp family.

2024526:LXD69 RS05100
gene id: 2024526:LXD69_RS05100
uniprot id: A0A8T9UEU8
names: Similarity
messages: Belongs to the peptidase S41A family.

2024526:LXD69 RS14795
gene id: 2024526:LXD69_RS14795
uniprot id: A0A8T9UAN8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2024526:LXD69 RS08865
gene id: 2024526:LXD69_RS08865
uniprot id: A0A8T9U341
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS12870
gene id: 2024526:LXD69_RS12870
uniprot id: A0A8T9U7T7
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS12165
gene id: 2024526:LXD69_RS12165
uniprot id: A0A8T9U649
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS16510
gene id: 2024526:LXD69_RS16510
uniprot id: A0A8T9UBN8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2024526:LXD69 RS04155
gene id: 2024526:LXD69_RS04155
uniprot id: A0A8T9UC14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2024526:LXD69 RS11415
gene id: 2024526:LXD69_RS11415
uniprot id: A0A8T9U5P5
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS09450
gene id: 2024526:LXD69_RS09450
uniprot id: A0A8T9U7Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2024526:LXD69 RS07695
gene id: 2024526:LXD69_RS07695
uniprot id: A0A8T9UFZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2024526:LXD69 RS09705
gene id: 2024526:LXD69_RS09705
uniprot id: A0A8T9U657
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2024526:LXD69 RS07985
gene id: 2024526:LXD69_RS07985
uniprot id: A0A8T9UFW7
names: Similarity
messages: Belongs to the SusD family.

2024526:LXD69 RS09260
gene id: 2024526:LXD69_RS09260
uniprot id: A0A8T9U4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2024526:LXD69 RS07105
gene id: 2024526:LXD69_RS07105
uniprot id: A0A8T9UCX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

2024526:LXD69 RS00910
gene id: 2024526:LXD69_RS00910
uniprot id: A0A8T9UB39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2024526:LXD69 RS06815
gene id: 2024526:LXD69_RS06815
uniprot id: A0A8T9UDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

2024526:LXD69 RS06545
gene id: 2024526:LXD69_RS06545
uniprot id: A0A8T9UFF7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2024526:LXD69 RS01995
gene id: 2024526:LXD69_RS01995
uniprot id: A0A8T9UDF1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2024526:LXD69 RS07570
gene id: 2024526:LXD69_RS07570
uniprot id: A0A8T9UFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

2024526:LXD69 RS11840
gene id: 2024526:LXD69_RS11840
uniprot id: A0A8T9U5Y5
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS09855
gene id: 2024526:LXD69_RS09855
uniprot id: A0A8T9U835
names: Similarity
messages: Belongs to the group II decarboxylase family.

2024526:LXD69 RS00855
gene id: 2024526:LXD69_RS00855
uniprot id: A0A8T9UCJ1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2024526:LXD69 RS04080
gene id: 2024526:LXD69_RS04080
uniprot id: A0A8T9UEE3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2024526:LXD69 RS14005
gene id: 2024526:LXD69_RS14005
uniprot id: A0A8T9U616
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2024526:LXD69 RS03785
gene id: 2024526:LXD69_RS03785
uniprot id: A0A8T9UEG8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2024526:LXD69 RS04465
gene id: 2024526:LXD69_RS04465
uniprot id: A0A8T9UEU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2024526:LXD69 RS03295
gene id: 2024526:LXD69_RS03295
uniprot id: A0A8T9UEA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

2024526:LXD69 RS15250
gene id: 2024526:LXD69_RS15250
uniprot id: A0A8T9U935
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2024526:LXD69 RS00775
gene id: 2024526:LXD69_RS00775
uniprot id: A0A8T9UCS5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

2024526:LXD69 RS02645
gene id: 2024526:LXD69_RS02645
uniprot id: A0A8T9UE04
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2024526:LXD69 RS00945
gene id: 2024526:LXD69_RS00945
uniprot id: A0A8T9UE73
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2024526:LXD69 RS14895
gene id: 2024526:LXD69_RS14895
uniprot id: A0A8T9U8W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2024526:LXD69 RS10840
gene id: 2024526:LXD69_RS10840
uniprot id: A0A8T9U4L6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2024526:LXD69 RS04130
gene id: 2024526:LXD69_RS04130
uniprot id: A0A8T9UB98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2024526:LXD69 RS09845
gene id: 2024526:LXD69_RS09845
uniprot id: A0A8T9U7Q9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

2024526:LXD69 RS07780
gene id: 2024526:LXD69_RS07780
uniprot id: A0A8T9UD85
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2024526:LXD69 RS17445
gene id: 2024526:LXD69_RS17445
uniprot id: A0A8T9UAA6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2024526:LXD69 RS07415
gene id: 2024526:LXD69_RS07415
uniprot id: A0A8T9UFQ7
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS05770
gene id: 2024526:LXD69_RS05770
uniprot id: A0A8T9UC76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2024526:LXD69 RS01715
gene id: 2024526:LXD69_RS01715
uniprot id: A0A8T9U880
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

2024526:LXD69 RS10890
gene id: 2024526:LXD69_RS10890
uniprot id: A0A8T9UGC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2024526:LXD69 RS11135
gene id: 2024526:LXD69_RS11135
uniprot id: A0A8T9U6W3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

2024526:LXD69 RS05985
gene id: 2024526:LXD69_RS05985
uniprot id: A0A8T9UF74
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS11830
gene id: 2024526:LXD69_RS11830
uniprot id: A0A8T9U900
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2024526:LXD69 RS05720
gene id: 2024526:LXD69_RS05720
uniprot id: A0A8T9UF40
names: Similarity
messages: Belongs to the peptidase S66 family.

2024526:LXD69 RS02665
gene id: 2024526:LXD69_RS02665
uniprot id: A0A8T9UC30
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

2024526:LXD69 RS06405
gene id: 2024526:LXD69_RS06405
uniprot id: A0A8T9UDB4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2024526:LXD69 RS06230
gene id: 2024526:LXD69_RS06230
uniprot id: A0A8T9UDU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2024526:LXD69 RS10640
gene id: 2024526:LXD69_RS10640
uniprot id: A0A8T9U4G7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2024526:LXD69 RS02480
gene id: 2024526:LXD69_RS02480
uniprot id: A0A8T9UCB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2024526:LXD69 RS10590
gene id: 2024526:LXD69_RS10590
uniprot id: A0A8T9U4F5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2024526:LXD69 RS12175
gene id: 2024526:LXD69_RS12175
uniprot id: A0A8T9U929
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2024526:LXD69 RS03025
gene id: 2024526:LXD69_RS03025
uniprot id: A0A8T9UBG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS06755
gene id: 2024526:LXD69_RS06755
uniprot id: A0A8T9UFI2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2024526:LXD69 RS11870
gene id: 2024526:LXD69_RS11870
uniprot id: A0A8T9U4R3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2024526:LXD69 RS12050
gene id: 2024526:LXD69_RS12050
uniprot id: A0A8T9U599
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2024526:LXD69 RS11280
gene id: 2024526:LXD69_RS11280
uniprot id: A0A8T9U8S8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2024526:LXD69 RS07025
gene id: 2024526:LXD69_RS07025
uniprot id: A0A8T9UGF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2024526:LXD69 RS06895
gene id: 2024526:LXD69_RS06895
uniprot id: A0A8T9UE58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2024526:LXD69 RS01000
gene id: 2024526:LXD69_RS01000
uniprot id: A0A8T9UD52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2024526:LXD69 RS09270
gene id: 2024526:LXD69_RS09270
uniprot id: A0A8T9U7F3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2024526:LXD69 RS00475
gene id: 2024526:LXD69_RS00475
uniprot id: A0A8T9UCC4
names: Similarity
messages: Belongs to the sterol desaturase family.

2024526:LXD69 RS07555
gene id: 2024526:LXD69_RS07555
uniprot id: A0A8T9UEG1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2024526:LXD69 RS09060
gene id: 2024526:LXD69_RS09060
uniprot id: A0A8T9U7R0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS03005
gene id: 2024526:LXD69_RS03005
uniprot id: A0A8T9U9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2024526:LXD69 RS04955
gene id: 2024526:LXD69_RS04955
uniprot id: A0A8T9UDQ4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2024526:LXD69 RS06375
gene id: 2024526:LXD69_RS06375
uniprot id: A0A8T9UEV7
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

2024526:LXD69 RS10920
gene id: 2024526:LXD69_RS10920
uniprot id: A0A8T9U735
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS04960
gene id: 2024526:LXD69_RS04960
uniprot id: A0A8T9UCH9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2024526:LXD69 RS12055
gene id: 2024526:LXD69_RS12055
uniprot id: A0A8T9U937
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

2024526:LXD69 RS10490
gene id: 2024526:LXD69_RS10490
uniprot id: A0A8T9U8A5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

2024526:LXD69 RS00120
gene id: 2024526:LXD69_RS00120
uniprot id: A0A8T9UAN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

2024526:LXD69 RS03850
gene id: 2024526:LXD69_RS03850
uniprot id: A0A8T9UDV3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

2024526:LXD69 RS00890
gene id: 2024526:LXD69_RS00890
uniprot id: A0A8T9UE65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2024526:LXD69 RS13525
gene id: 2024526:LXD69_RS13525
uniprot id: A0A8T9U9W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2024526:LXD69 RS07615
gene id: 2024526:LXD69_RS07615
uniprot id: A0A8T9UCC3
names: Similarity
messages: Belongs to the universal stress protein A family.

2024526:LXD69 RS12700
gene id: 2024526:LXD69_RS12700
uniprot id: A0A8T9U9E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

2024526:LXD69 RS03320
gene id: 2024526:LXD69_RS03320
uniprot id: A0A8T9UAT9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

2024526:LXD69 RS12875
gene id: 2024526:LXD69_RS12875
uniprot id: A0A8T9U5D6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

2024526:LXD69 RS06995
gene id: 2024526:LXD69_RS06995
uniprot id: A0A8T9UE88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

2024526:LXD69 RS06575
gene id: 2024526:LXD69_RS06575
uniprot id: A0A8T9UEY4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2024526:LXD69 RS11060
gene id: 2024526:LXD69_RS11060
uniprot id: A0A8T9U5F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2024526:LXD69 RS11055
gene id: 2024526:LXD69_RS11055
uniprot id: A0A8T9U755
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2024526:LXD69 RS17900
gene id: 2024526:LXD69_RS17900
uniprot id: A0A8T9UCI3
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS00385
gene id: 2024526:LXD69_RS00385
uniprot id: A0A8T9U948
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

2024526:LXD69 RS14590
gene id: 2024526:LXD69_RS14590
uniprot id: A0A8T9U7M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2024526:LXD69 RS00115
gene id: 2024526:LXD69_RS00115
uniprot id: A0A8T9UC57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

2024526:LXD69 RS14160
gene id: 2024526:LXD69_RS14160
uniprot id: A0A8T9U6L5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS15210
gene id: 2024526:LXD69_RS15210
uniprot id: A0A8T9U7A5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2024526:LXD69 RS07895
gene id: 2024526:LXD69_RS07895
uniprot id: A0A8T9UE29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

2024526:LXD69 RS08310
gene id: 2024526:LXD69_RS08310
uniprot id: A0A8T9UG60
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

2024526:LXD69 RS06680
gene id: 2024526:LXD69_RS06680
uniprot id: A0A8T9UF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2024526:LXD69 RS12435
gene id: 2024526:LXD69_RS12435
uniprot id: A0A8T9UFA4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

2024526:LXD69 RS15790
gene id: 2024526:LXD69_RS15790
uniprot id: A0A8T9UCN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2024526:LXD69 RS10300
gene id: 2024526:LXD69_RS10300
uniprot id: A0A8T9U9X0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

2024526:LXD69 RS02255
gene id: 2024526:LXD69_RS02255
uniprot id: A0A8T9UDJ5
names: Similarity
messages: Belongs to the NAD synthetase family.

2024526:LXD69 RS07905
gene id: 2024526:LXD69_RS07905
uniprot id: A0A8T9UG15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS02285
gene id: 2024526:LXD69_RS02285
uniprot id: A0A8T9UD77
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2024526:LXD69 RS02860
gene id: 2024526:LXD69_RS02860
uniprot id: A0A8T9UAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2024526:LXD69 RS07735
gene id: 2024526:LXD69_RS07735
uniprot id: A0A8T9UEU9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

2024526:LXD69 RS03015
gene id: 2024526:LXD69_RS03015
uniprot id: A0A8T9UDV8
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS08555
gene id: 2024526:LXD69_RS08555
uniprot id: A0A8T9UEC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2024526:LXD69 RS01395
gene id: 2024526:LXD69_RS01395
uniprot id: A0A8T9UAH3
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS01370
gene id: 2024526:LXD69_RS01370
uniprot id: A0A8T9UBD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2024526:LXD69 RS15095
gene id: 2024526:LXD69_RS15095
uniprot id: A0A8T9UAN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

2024526:LXD69 RS12315
gene id: 2024526:LXD69_RS12315
uniprot id: A0A8T9U7V2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2024526:LXD69 RS08730
gene id: 2024526:LXD69_RS08730
uniprot id: A0A8T9UBW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2024526:LXD69 RS09360
gene id: 2024526:LXD69_RS09360
uniprot id: A0A8T9U4H1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2024526:LXD69 RS13475
gene id: 2024526:LXD69_RS13475
uniprot id: A0A8T9U9V6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS11205
gene id: 2024526:LXD69_RS11205
uniprot id: A0A8T9U786
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2024526:LXD69 RS07625
gene id: 2024526:LXD69_RS07625
uniprot id: A0A8T9UFS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2024526:LXD69 RS12105
gene id: 2024526:LXD69_RS12105
uniprot id: A0A8T9U946
names: Similarity
messages: Belongs to the glutamine synthetase family.

2024526:LXD69 RS09130
gene id: 2024526:LXD69_RS09130
uniprot id: A0A8T9U7J2
names: Subcellular Location Annotation
messages: Periplasm

2024526:LXD69 RS03190
gene id: 2024526:LXD69_RS03190
uniprot id: A0A8T9U8Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2024526:LXD69 RS10635
gene id: 2024526:LXD69_RS10635
uniprot id: A0A8T9U437
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

2024526:LXD69 RS08695
gene id: 2024526:LXD69_RS08695
uniprot id: A0A8T9UDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2024526:LXD69 RS16320
gene id: 2024526:LXD69_RS16320
uniprot id: A0A8T9UB90
names: Similarity
messages: Belongs to the LOG family.

2024526:LXD69 RS00900
gene id: 2024526:LXD69_RS00900
uniprot id: A0A8T9U7R1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2024526:LXD69 RS01305
gene id: 2024526:LXD69_RS01305
uniprot id: A0A8T9U7Z3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2024526:LXD69 RS08820
gene id: 2024526:LXD69_RS08820
uniprot id: A0A8T9UEG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2024526:LXD69 RS00865
gene id: 2024526:LXD69_RS00865
uniprot id: A0A8T9U8P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2024526:LXD69 RS13220
gene id: 2024526:LXD69_RS13220
uniprot id: A0A8T9U4V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

2024526:LXD69 RS00990
gene id: 2024526:LXD69_RS00990
uniprot id: A0A8T9UA88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2024526:LXD69 RS01280
gene id: 2024526:LXD69_RS01280
uniprot id: A0A8T9UD31
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2024526:LXD69 RS15985
gene id: 2024526:LXD69_RS15985
uniprot id: A0A8T9UB86
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2024526:LXD69 RS14760
gene id: 2024526:LXD69_RS14760
uniprot id: A0A8T9UC74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

2024526:LXD69 RS05690
gene id: 2024526:LXD69_RS05690
uniprot id: A0A8T9UFE2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2024526:LXD69 RS13805
gene id: 2024526:LXD69_RS13805
uniprot id: A0A8T9U6D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2024526:LXD69 RS07055
gene id: 2024526:LXD69_RS07055
uniprot id: A0A8T9UCW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

2024526:LXD69 RS03345
gene id: 2024526:LXD69_RS03345
uniprot id: A0A8T9UEB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

2024526:LXD69 RS04095
gene id: 2024526:LXD69_RS04095
uniprot id: A0A8T9UFG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2024526:LXD69 RS00980
gene id: 2024526:LXD69_RS00980
uniprot id: A0A8T9UCW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2024526:LXD69 RS04085
gene id: 2024526:LXD69_RS04085
uniprot id: A0A8T9UD47
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2024526:LXD69 RS14880
gene id: 2024526:LXD69_RS14880
uniprot id: A0A8T9UAQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2024526:LXD69 RS11100
gene id: 2024526:LXD69_RS11100
uniprot id: A0A8T9U8K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2024526:LXD69 RS09740
gene id: 2024526:LXD69_RS09740
uniprot id: A0A8T9UF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS05725
gene id: 2024526:LXD69_RS05725
uniprot id: A0A8T9UDX3
names: Similarity
messages: Belongs to the UPF0102 family.

2024526:LXD69 RS16335
gene id: 2024526:LXD69_RS16335
uniprot id: A0A8T9U7W4
names: Similarity
messages: Belongs to the thioredoxin family.

2024526:LXD69 RS08575
gene id: 2024526:LXD69_RS08575
uniprot id: A0A8T9UFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2024526:LXD69 RS11445
gene id: 2024526:LXD69_RS11445
uniprot id: A0A8T9U4I6
names: Similarity
messages: Belongs to the ArsC family.

2024526:LXD69 RS07655
gene id: 2024526:LXD69_RS07655
uniprot id: A0A8T9UFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

2024526:LXD69 RS09775
gene id: 2024526:LXD69_RS09775
uniprot id: A0A8T9U7X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2024526:LXD69 RS09700
gene id: 2024526:LXD69_RS09700
uniprot id: A0A8T9U810
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2024526:LXD69 RS17990
gene id: 2024526:LXD69_RS17990
uniprot id: A0A8T9U9M6
names: Similarity
messages: Belongs to the IMPACT family.

2024526:LXD69 RS00935
gene id: 2024526:LXD69_RS00935
uniprot id: A0A8T9UBG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2024526:LXD69 RS09350
gene id: 2024526:LXD69_RS09350
uniprot id: A0A8T9U7N6
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

2024526:LXD69 RS07440
gene id: 2024526:LXD69_RS07440
uniprot id: A0A8T9UB88
names: Subcellular Location Annotation
messages: Cytoplasm

2024526:LXD69 RS09285
gene id: 2024526:LXD69_RS09285
uniprot id: A0A8T9U5Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2024526:LXD69 RS03505
gene id: 2024526:LXD69_RS03505
uniprot id: A0A8T9UCU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

2024526:LXD69 RS00885
gene id: 2024526:LXD69_RS00885
uniprot id: A0A8T9UA64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2024526:LXD69 RS03185
gene id: 2024526:LXD69_RS03185
uniprot id: A0A8T9UE90
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2024526:LXD69 RS07430
gene id: 2024526:LXD69_RS07430
uniprot id: A0A8T9UGI1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2024526:LXD69 RS06085
gene id: 2024526:LXD69_RS06085
uniprot id: A0A8T9UCD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2024526:LXD69 RS06335
gene id: 2024526:LXD69_RS06335
uniprot id: A0A8T9UBM6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2024526:LXD69 RS08915
gene id: 2024526:LXD69_RS08915
uniprot id: A0A8T9U354
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2024526:LXD69 RS03725
gene id: 2024526:LXD69_RS03725
uniprot id: A0A8T9U984
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

2024526:LXD69 RS10940
gene id: 2024526:LXD69_RS10940
uniprot id: A0A8T9U3M4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

2024526:LXD69 RS06490
gene id: 2024526:LXD69_RS06490
uniprot id: A0A8T9UCL1
names: Similarity
messages: Belongs to the group II decarboxylase family.

2024526:LXD69 RS00955
gene id: 2024526:LXD69_RS00955
uniprot id: A0A8T9U7S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2024526:LXD69 RS09425
gene id: 2024526:LXD69_RS09425
uniprot id: A0A8T9U2V6
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS16205
gene id: 2024526:LXD69_RS16205
uniprot id: A0A8T9UBH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2024526:LXD69 RS06650
gene id: 2024526:LXD69_RS06650
uniprot id: A0A8T9UFG5
names: Similarity
messages: Belongs to the sigma-54 factor family.

2024526:LXD69 RS06435
gene id: 2024526:LXD69_RS06435
uniprot id: A0A8T9UBP7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2024526:LXD69 RS17180
gene id: 2024526:LXD69_RS17180
uniprot id: A0A8T9UC36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

2024526:LXD69 RS01870
gene id: 2024526:LXD69_RS01870
uniprot id: A0A8T9UD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2024526:LXD69 RS09325
gene id: 2024526:LXD69_RS09325
uniprot id: A0A8T9U2S9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2024526:LXD69 RS00005
gene id: 2024526:LXD69_RS00005
uniprot id: A0A8T9UCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2024526:LXD69 RS15980
gene id: 2024526:LXD69_RS15980
uniprot id: A0A8T9U7P3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2024526:LXD69 RS00110
gene id: 2024526:LXD69_RS00110
uniprot id: A0A8T9U7C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

2024526:LXD69 RS00040
gene id: 2024526:LXD69_RS00040
uniprot id: A0A8T9UAZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS09250
gene id: 2024526:LXD69_RS09250
uniprot id: A0A8T9U671
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2024526:LXD69 RS08830
gene id: 2024526:LXD69_RS08830
uniprot id: A0A8T9UGB8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2024526:LXD69 RS04600
gene id: 2024526:LXD69_RS04600
uniprot id: A0A8T9UDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

2024526:LXD69 RS03820
gene id: 2024526:LXD69_RS03820
uniprot id: A0A8T9UE94
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

2024526:LXD69 RS05925
gene id: 2024526:LXD69_RS05925
uniprot id: A0A8T9UBE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2024526:LXD69 RS02410
gene id: 2024526:LXD69_RS02410
uniprot id: A0A8T9UBY3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

2024526:LXD69 RS06455
gene id: 2024526:LXD69_RS06455
uniprot id: A0A8T9UDC6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

2024526:LXD69 RS13560
gene id: 2024526:LXD69_RS13560
uniprot id: A0A8T9U8J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS04940
gene id: 2024526:LXD69_RS04940
uniprot id: A0A8T9UBQ9
names: Similarity
messages: Belongs to the SufE family.

2024526:LXD69 RS06945
gene id: 2024526:LXD69_RS06945
uniprot id: A0A8T9UE68
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS13495
gene id: 2024526:LXD69_RS13495
uniprot id: A0A8T9U5R2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS03300
gene id: 2024526:LXD69_RS03300
uniprot id: A0A8T9U911
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2024526:LXD69 RS17865
gene id: 2024526:LXD69_RS17865
uniprot id: A0A8T9UAI2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2024526:LXD69 RS07790
gene id: 2024526:LXD69_RS07790
uniprot id: A0A8T9UEV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

2024526:LXD69 RS00970
gene id: 2024526:LXD69_RS00970
uniprot id: A0A8T9U8R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2024526:LXD69 RS09735
gene id: 2024526:LXD69_RS09735
uniprot id: A0A8T9U9M1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS02715
gene id: 2024526:LXD69_RS02715
uniprot id: A0A8T9UGE8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

2024526:LXD69 RS17155
gene id: 2024526:LXD69_RS17155
uniprot id: A0A8T9U8D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2024526:LXD69 RS03580
gene id: 2024526:LXD69_RS03580
uniprot id: A0A8T9UDR8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

2024526:LXD69 RS01240
gene id: 2024526:LXD69_RS01240
uniprot id: A0A8T9UAD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2024526:LXD69 RS14140
gene id: 2024526:LXD69_RS14140
uniprot id: A0A8T9U5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2024526:LXD69 RS08010
gene id: 2024526:LXD69_RS08010
uniprot id: A0A8T9UG28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS03640
gene id: 2024526:LXD69_RS03640
uniprot id: A0A8T9UA58
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2024526:LXD69 RS15845
gene id: 2024526:LXD69_RS15845
uniprot id: A0A8T9U8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

2024526:LXD69 RS08300
gene id: 2024526:LXD69_RS08300
uniprot id: A0A8T9UE85
names: Similarity
messages: Belongs to the peptidase C40 family.

2024526:LXD69 RS00870
gene id: 2024526:LXD69_RS00870
uniprot id: A0A8T9U9D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2024526:LXD69 RS05275
gene id: 2024526:LXD69_RS05275
uniprot id: A0A8T9UF79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

2024526:LXD69 RS06205
gene id: 2024526:LXD69_RS06205
uniprot id: A0A8T9UG59
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2024526:LXD69 RS07795
gene id: 2024526:LXD69_RS07795
uniprot id: A0A8T9UE17
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS12305
gene id: 2024526:LXD69_RS12305
uniprot id: A0A8T9U5F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2024526:LXD69 RS01400
gene id: 2024526:LXD69_RS01400
uniprot id: A0A8T9UEF2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2024526:LXD69 RS11000
gene id: 2024526:LXD69_RS11000
uniprot id: A0A8T9U8N1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2024526:LXD69 RS16815
gene id: 2024526:LXD69_RS16815
uniprot id: A0A8T9UD16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2024526:LXD69 RS05900
gene id: 2024526:LXD69_RS05900
uniprot id: A0A8T9UAE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2024526:LXD69 RS03045
gene id: 2024526:LXD69_RS03045
uniprot id: A0A8T9UDJ0
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS08385
gene id: 2024526:LXD69_RS08385
uniprot id: A0A8T9UCQ3
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS11965
gene id: 2024526:LXD69_RS11965
uniprot id: A0A8T9U604
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS16820
gene id: 2024526:LXD69_RS16820
uniprot id: A0A8T9UBW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2024526:LXD69 RS07005
gene id: 2024526:LXD69_RS07005
uniprot id: A0A8T9UCV8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS06780
gene id: 2024526:LXD69_RS06780
uniprot id: A0A8T9UAW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2024526:LXD69 RS09275
gene id: 2024526:LXD69_RS09275
uniprot id: A0A8T9U2S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2024526:LXD69 RS14625
gene id: 2024526:LXD69_RS14625
uniprot id: A0A8T9U6Y1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

2024526:LXD69 RS00925
gene id: 2024526:LXD69_RS00925
uniprot id: A0A8T9UCV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2024526:LXD69 RS00420
gene id: 2024526:LXD69_RS00420
uniprot id: A0A8T9UCB4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

2024526:LXD69 RS02015
gene id: 2024526:LXD69_RS02015
uniprot id: A0A8T9UDQ3
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS15265
gene id: 2024526:LXD69_RS15265
uniprot id: A0A8T9UAW5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

2024526:LXD69 RS02070
gene id: 2024526:LXD69_RS02070
uniprot id: A0A8T9U8E0
names: Similarity
messages: Belongs to the DNase I family.

2024526:LXD69 RS14600
gene id: 2024526:LXD69_RS14600
uniprot id: A0A8T9UAK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2024526:LXD69 RS03655
gene id: 2024526:LXD69_RS03655
uniprot id: A0A8T9UCX0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

2024526:LXD69 RS05780
gene id: 2024526:LXD69_RS05780
uniprot id: A0A8T9UDY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2024526:LXD69 RS15360
gene id: 2024526:LXD69_RS15360
uniprot id: A0A8T9U5Y8
names: Similarity
messages: Belongs to the AHA1 family.

2024526:LXD69 RS07825
gene id: 2024526:LXD69_RS07825
uniprot id: A0A8T9UCF6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2024526:LXD69 RS08015
gene id: 2024526:LXD69_RS08015
uniprot id: A0A8T9UBI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2024526:LXD69 RS08690
gene id: 2024526:LXD69_RS08690
uniprot id: A0A8T9UCV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2024526:LXD69 RS03830
gene id: 2024526:LXD69_RS03830
uniprot id: A0A8T9UBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS07560
gene id: 2024526:LXD69_RS07560
uniprot id: A0A8T9UCB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2024526:LXD69 RS16275
gene id: 2024526:LXD69_RS16275
uniprot id: A0A8T9U795
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

2024526:LXD69 RS02470
gene id: 2024526:LXD69_RS02470
uniprot id: A0A8T9UAB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

2024526:LXD69 RS04890
gene id: 2024526:LXD69_RS04890
uniprot id: A0A8T9UBP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

2024526:LXD69 RS03540
gene id: 2024526:LXD69_RS03540
uniprot id: A0A8T9UA38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

2024526:LXD69 RS16710
gene id: 2024526:LXD69_RS16710
uniprot id: A0A8T9UD48
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2024526:LXD69 RS14840
gene id: 2024526:LXD69_RS14840
uniprot id: A0A8T9U8V3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2024526:LXD69 RS17215
gene id: 2024526:LXD69_RS17215
uniprot id: A0A8T9UAG3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2024526:LXD69 RS04255
gene id: 2024526:LXD69_RS04255
uniprot id: A0A8T9UC32
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2024526:LXD69 RS02890
gene id: 2024526:LXD69_RS02890
uniprot id: A0A8T9U8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2024526:LXD69 RS00905
gene id: 2024526:LXD69_RS00905
uniprot id: A0A8T9UCJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2024526:LXD69 RS00895
gene id: 2024526:LXD69_RS00895
uniprot id: A0A8T9UD33
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2024526:LXD69 RS03255
gene id: 2024526:LXD69_RS03255
uniprot id: A0A8T9UCC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

2024526:LXD69 RS14865
gene id: 2024526:LXD69_RS14865
uniprot id: A0A8T9U7S6
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

2024526:LXD69 RS14995
gene id: 2024526:LXD69_RS14995
uniprot id: A0A8T9UAL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

2024526:LXD69 RS00915
gene id: 2024526:LXD69_RS00915
uniprot id: A0A8T9U8Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2024526:LXD69 RS10310
gene id: 2024526:LXD69_RS10310
uniprot id: A0A8T9U3A7
names: Subcellular Location Annotation
messages: Membrane

2024526:LXD69 RS15270
gene id: 2024526:LXD69_RS15270
uniprot id: A0A8T9U9F1
names: Similarity
messages: Belongs to the SUI1 family.

2024526:LXD69 RS09290
gene id: 2024526:LXD69_RS09290
uniprot id: A0A8T9U3C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2024526:LXD69 RS10935
gene id: 2024526:LXD69_RS10935
uniprot id: A0A8T9U8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2024526:LXD69 RS12925
gene id: 2024526:LXD69_RS12925
uniprot id: A0A8T9U5E6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS11865
gene id: 2024526:LXD69_RS11865
uniprot id: A0A8T9U7A7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2024526:LXD69 RS12170
gene id: 2024526:LXD69_RS12170
uniprot id: A0A8T9UAU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2024526:LXD69 RS03515
gene id: 2024526:LXD69_RS03515
uniprot id: A0A8T9UF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2024526:LXD69 RS14450
gene id: 2024526:LXD69_RS14450
uniprot id: A0A8T9U5J3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane