199:CCON33237 RS07150
gene id: 199:CCON33237_RS07150
uniprot id: A0A0M5MEK7
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS06300
gene id: 199:CCON33237_RS06300
uniprot id: A0A0M3V2H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

199:CCON33237 RS03830
gene id: 199:CCON33237_RS03830
uniprot id: A0A0M3V2B8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS05365
gene id: 199:CCON33237_RS05365
uniprot id: A0A0M3V2H7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

199:CCON33237 RS01685
gene id: 199:CCON33237_RS01685
uniprot id: A0A0M4TLV0
names: Similarity
messages: Belongs to the nitroreductase family.

199:CCON33237 RS07330
gene id: 199:CCON33237_RS07330
uniprot id: A0A0M5TIA8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

199:CCON33237 RS05270
gene id: 199:CCON33237_RS05270
uniprot id: A0A0M4TN26
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

199:CCON33237 RS07295
gene id: 199:CCON33237_RS07295
uniprot id: A0A0M5MF42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

199:CCON33237 RS05055
gene id: 199:CCON33237_RS05055
uniprot id: A0A0M4SMT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

199:CCON33237 RS00575
gene id: 199:CCON33237_RS00575
uniprot id: A0A0M5MK43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

199:CCON33237 RS02450
gene id: 199:CCON33237_RS02450
uniprot id: A0A0M5ME79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

199:CCON33237 RS01890
gene id: 199:CCON33237_RS01890
uniprot id: A0A0M4STF2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

199:CCON33237 RS08300
gene id: 199:CCON33237_RS08300
uniprot id: A0A0M4SII9
names: Similarity
messages: Belongs to the citrate synthase family.

199:CCON33237 RS00085
gene id: 199:CCON33237_RS00085
uniprot id: A0A0M4T9Q8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

199:CCON33237 RS02070
gene id: 199:CCON33237_RS02070
uniprot id: A0A1L9R310
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

199:CCON33237 RS08440
gene id: 199:CCON33237_RS08440
uniprot id: A0A0M3V2Q1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

199:CCON33237 RS06245
gene id: 199:CCON33237_RS06245
uniprot id: A0A0M3V2G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

199:CCON33237 RS04900
gene id: 199:CCON33237_RS04900
uniprot id: A0A0M4TM86
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

199:CCON33237 RS08800
gene id: 199:CCON33237_RS08800
uniprot id: A0A0M4TNG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

199:CCON33237 RS05855
gene id: 199:CCON33237_RS05855
uniprot id: A0A0M4TN86
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS01105
gene id: 199:CCON33237_RS01105
uniprot id: A0A0M4TLN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

199:CCON33237 RS01390
gene id: 199:CCON33237_RS01390
uniprot id: A0A0M3V224
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

199:CCON33237 RS01055
gene id: 199:CCON33237_RS01055
uniprot id: A0A0M4ST50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

199:CCON33237 RS06735
gene id: 199:CCON33237_RS06735
uniprot id: A0A0M4SV26
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

199:CCON33237 RS06065
gene id: 199:CCON33237_RS06065
uniprot id: A0A0M3V2G3
names: Similarity
messages: Belongs to the MotB family.

199:CCON33237 RS02605
gene id: 199:CCON33237_RS02605
uniprot id: A0A0M5MEK9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

199:CCON33237 RS02330
gene id: 199:CCON33237_RS02330
uniprot id: A0A0M5TI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

199:CCON33237 RS07465
gene id: 199:CCON33237_RS07465
uniprot id: A0A0M4SI88
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

199:CCON33237 RS07575
gene id: 199:CCON33237_RS07575
uniprot id: A0A0M4SCJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS02630
gene id: 199:CCON33237_RS02630
uniprot id: A0A0M3V275
names: Similarity
messages: Belongs to the peptidase S49 family.

199:CCON33237 RS06410
gene id: 199:CCON33237_RS06410
uniprot id: A0A0M4SUZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS00820
gene id: 199:CCON33237_RS00820
uniprot id: A0A0M4TKU4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

199:CCON33237 RS02195
gene id: 199:CCON33237_RS02195
uniprot id: A0A0M5ME81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

199:CCON33237 RS09095
gene id: 199:CCON33237_RS09095
uniprot id: A0A0M4SP75
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

199:CCON33237 RS02285
gene id: 199:CCON33237_RS02285
uniprot id: A0A0M4STJ8
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

199:CCON33237 RS08695
gene id: 199:CCON33237_RS08695
uniprot id: A0A0M4SP34
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

199:CCON33237 RS00845
gene id: 199:CCON33237_RS00845
uniprot id: A0A0M4T9Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS04445
gene id: 199:CCON33237_RS04445
uniprot id: A0A0M4ST45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

199:CCON33237 RS00375
gene id: 199:CCON33237_RS00375
uniprot id: A0A0M4TLG4
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS07800
gene id: 199:CCON33237_RS07800
uniprot id: A0A0M3V2S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

199:CCON33237 RS05085
gene id: 199:CCON33237_RS05085
uniprot id: A0A0M4SHH8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

199:CCON33237 RS06430
gene id: 199:CCON33237_RS06430
uniprot id: A0A0M4STX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

199:CCON33237 RS05390
gene id: 199:CCON33237_RS05390
uniprot id: A0A0M5MG47
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

199:CCON33237 RS03225
gene id: 199:CCON33237_RS03225
uniprot id: A0A0M5MIJ9
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS08765
gene id: 199:CCON33237_RS08765
uniprot id: A0A0M4TCT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

199:CCON33237 RS04435
gene id: 199:CCON33237_RS04435
uniprot id: A0A0M5MEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

199:CCON33237 RS07795
gene id: 199:CCON33237_RS07795
uniprot id: A0A0M4SVG4
names: Similarity
messages: Belongs to the pyruvate kinase family.

199:CCON33237 RS03030
gene id: 199:CCON33237_RS03030
uniprot id: A0A0M3V289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

199:CCON33237 RS07130
gene id: 199:CCON33237_RS07130
uniprot id: A0A0M4SNI0
names: Similarity
messages: Belongs to the universal stress protein A family.

199:CCON33237 RS06170
gene id: 199:CCON33237_RS06170
uniprot id: A0A0M4STT8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS04800
gene id: 199:CCON33237_RS04800
uniprot id: A0A0M4TMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

199:CCON33237 RS01905
gene id: 199:CCON33237_RS01905
uniprot id: A0A0M3V245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS05175
gene id: 199:CCON33237_RS05175
uniprot id: A0A0M4STI1
names: Similarity
messages: Belongs to the TrpC family.

199:CCON33237 RS08790
gene id: 199:CCON33237_RS08790
uniprot id: A0A0M4SVU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

199:CCON33237 RS04650
gene id: 199:CCON33237_RS04650
uniprot id: A0A0M3V2A9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

199:CCON33237 RS08875
gene id: 199:CCON33237_RS08875
uniprot id: A0A0M4SP52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

199:CCON33237 RS03585
gene id: 199:CCON33237_RS03585
uniprot id: A0A0M4TLR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

199:CCON33237 RS01490
gene id: 199:CCON33237_RS01490
uniprot id: A0A0M3V229
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

199:CCON33237 RS04860
gene id: 199:CCON33237_RS04860
uniprot id: A0A0M5MEK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

199:CCON33237 RS08050
gene id: 199:CCON33237_RS08050
uniprot id: A0A0M3V2T0
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS08110
gene id: 199:CCON33237_RS08110
uniprot id: A0A0M4SIG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS03495
gene id: 199:CCON33237_RS03495
uniprot id: A0A0M4SGY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

199:CCON33237 RS01180
gene id: 199:CCON33237_RS01180
uniprot id: A0A0M4SG82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS09500
gene id: 199:CCON33237_RS09500
uniprot id: A0A0M4SCZ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

199:CCON33237 RS06835
gene id: 199:CCON33237_RS06835
uniprot id: A0A0M4TMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS05180
gene id: 199:CCON33237_RS05180
uniprot id: A0A0M4SMU9
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

199:CCON33237 RS01740
gene id: 199:CCON33237_RS01740
uniprot id: A0A0M5MFT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

199:CCON33237 RS02515
gene id: 199:CCON33237_RS02515
uniprot id: A0A0M4TAJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS02430
gene id: 199:CCON33237_RS02430
uniprot id: A0A0M4SSE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

199:CCON33237 RS01730
gene id: 199:CCON33237_RS01730
uniprot id: A0A0M3V200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

199:CCON33237 RS08865
gene id: 199:CCON33237_RS08865
uniprot id: A0A0M4TNH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

199:CCON33237 RS08815
gene id: 199:CCON33237_RS08815
uniprot id: A0A0M4SP49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

199:CCON33237 RS04950
gene id: 199:CCON33237_RS04950
uniprot id: A0A0M4SUJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

199:CCON33237 RS00780
gene id: 199:CCON33237_RS00780
uniprot id: A0A0M4SA35
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS01630
gene id: 199:CCON33237_RS01630
uniprot id: A0A0M3V1Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

199:CCON33237 RS04295
gene id: 199:CCON33237_RS04295
uniprot id: A0A0M3V294
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS08905
gene id: 199:CCON33237_RS08905
uniprot id: A0A0M3V2W2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

199:CCON33237 RS01705
gene id: 199:CCON33237_RS01705
uniprot id: A0A0M5ME64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS08225
gene id: 199:CCON33237_RS08225
uniprot id: A0A0M5MKR1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

199:CCON33237 RS00075
gene id: 199:CCON33237_RS00075
uniprot id: A0A0M4S9V7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

199:CCON33237 RS06650
gene id: 199:CCON33237_RS06650
uniprot id: A0A0M4TC19
names: Similarity
messages: Belongs to the aspartokinase family.

199:CCON33237 RS09300
gene id: 199:CCON33237_RS09300
uniprot id: A0A0M5TIB8
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS06050
gene id: 199:CCON33237_RS06050
uniprot id: A0A0M4SHT9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

199:CCON33237 RS07235
gene id: 199:CCON33237_RS07235
uniprot id: A0A0M4TMZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

199:CCON33237 RS04995
gene id: 199:CCON33237_RS04995
uniprot id: A0A0M5TIA9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

199:CCON33237 RS09260
gene id: 199:CCON33237_RS09260
uniprot id: A0A0M5MFA2
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS03490
gene id: 199:CCON33237_RS03490
uniprot id: A0A0M4TMF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

199:CCON33237 RS09295
gene id: 199:CCON33237_RS09295
uniprot id: A0A0M4TD03
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS01070
gene id: 199:CCON33237_RS01070
uniprot id: A0A0M4TKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

199:CCON33237 RS03905
gene id: 199:CCON33237_RS03905
uniprot id: A0A0M4SSX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

199:CCON33237 RS00595
gene id: 199:CCON33237_RS00595
uniprot id: A0A0M4SSZ6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

199:CCON33237 RS04405
gene id: 199:CCON33237_RS04405
uniprot id: A0A1L9R1U2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

199:CCON33237 RS03450
gene id: 199:CCON33237_RS03450
uniprot id: A0A0M4TLQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

199:CCON33237 RS05970
gene id: 199:CCON33237_RS05970
uniprot id: A0A0M4TBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

199:CCON33237 RS05780
gene id: 199:CCON33237_RS05780
uniprot id: A0A0M4TBR4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

199:CCON33237 RS02920
gene id: 199:CCON33237_RS02920
uniprot id: A0A0M4SSK7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS01460
gene id: 199:CCON33237_RS01460
uniprot id: A0A0M4SLJ3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

199:CCON33237 RS02680
gene id: 199:CCON33237_RS02680
uniprot id: A0A0M3V277
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

199:CCON33237 RS05215
gene id: 199:CCON33237_RS05215
uniprot id: A0A0M4SHJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

199:CCON33237 RS03320
gene id: 199:CCON33237_RS03320
uniprot id: A0A0M3V258
names: Similarity
messages: Belongs to the YkuD family.

199:CCON33237 RS04895
gene id: 199:CCON33237_RS04895
uniprot id: A0A0M5MIP9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

199:CCON33237 RS03005
gene id: 199:CCON33237_RS03005
uniprot id: A0A0M5TIA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS05770
gene id: 199:CCON33237_RS05770
uniprot id: A0A0M4SN21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

199:CCON33237 RS09265
gene id: 199:CCON33237_RS09265
uniprot id: A0A0M3V2T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

199:CCON33237 RS03345
gene id: 199:CCON33237_RS03345
uniprot id: A0A0M4SGW9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS00730
gene id: 199:CCON33237_RS00730
uniprot id: A0A0M4TLJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

199:CCON33237 RS05210
gene id: 199:CCON33237_RS05210
uniprot id: A0A0M3V2H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

199:CCON33237 RS07285
gene id: 199:CCON33237_RS07285
uniprot id: A0A0M4SV91
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS07455
gene id: 199:CCON33237_RS07455
uniprot id: A0A0M5MEL7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

199:CCON33237 RS05325
gene id: 199:CCON33237_RS05325
uniprot id: A0A0M5TIA2
names: Similarity
messages: Belongs to the peptidase S51 family.

199:CCON33237 RS02995
gene id: 199:CCON33237_RS02995
uniprot id: A0A0M4SAW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

199:CCON33237 RS04535
gene id: 199:CCON33237_RS04535
uniprot id: A0A0M5MEJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

199:CCON33237 RS04660
gene id: 199:CCON33237_RS04660
uniprot id: A0A0M5TI95
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS07165
gene id: 199:CCON33237_RS07165
uniprot id: A0A0M4SV72
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

199:CCON33237 RS02580
gene id: 199:CCON33237_RS02580
uniprot id: A0A0M3V273
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

199:CCON33237 RS04710
gene id: 199:CCON33237_RS04710
uniprot id: A0A0M4SMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

199:CCON33237 RS00940
gene id: 199:CCON33237_RS00940
uniprot id: A0A0M4ST37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

199:CCON33237 RS03985
gene id: 199:CCON33237_RS03985
uniprot id: A0A0M3V2C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

199:CCON33237 RS08405
gene id: 199:CCON33237_RS08405
uniprot id: A0A0M4TCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

199:CCON33237 RS04335
gene id: 199:CCON33237_RS04335
uniprot id: A0A0M4TB81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

199:CCON33237 RS04890
gene id: 199:CCON33237_RS04890
uniprot id: A0A0M3V2F8
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

199:CCON33237 RS02400
gene id: 199:CCON33237_RS02400
uniprot id: A0A0M4SGL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

199:CCON33237 RS06205
gene id: 199:CCON33237_RS06205
uniprot id: A0A0M4SHV3
names: Similarity
messages: Belongs to the UPF0237 family.

199:CCON33237 RS02945
gene id: 199:CCON33237_RS02945
uniprot id: A0A0M5MKB9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

199:CCON33237 RS06255
gene id: 199:CCON33237_RS06255
uniprot id: A0A0M5MKL0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

199:CCON33237 RS05785
gene id: 199:CCON33237_RS05785
uniprot id: A0A0M3V2J3
names: Subcellular Location Annotation
messages: Mitochondrion

199:CCON33237 RS01720
gene id: 199:CCON33237_RS01720
uniprot id: A0A0M4SLM5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

199:CCON33237 RS02220
gene id: 199:CCON33237_RS02220
uniprot id: A0A0M3V259
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

199:CCON33237 RS03660
gene id: 199:CCON33237_RS03660
uniprot id: A0A0M4SMA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

199:CCON33237 RS04450
gene id: 199:CCON33237_RS04450
uniprot id: A0A0M3V2A0
names: Similarity
messages: Belongs to the glutamine synthetase family.

199:CCON33237 RS04330
gene id: 199:CCON33237_RS04330
uniprot id: A0A0M4SBD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

199:CCON33237 RS08365
gene id: 199:CCON33237_RS08365
uniprot id: A0A0M4SIJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

199:CCON33237 RS03615
gene id: 199:CCON33237_RS03615
uniprot id: A0A0M5MKD6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

199:CCON33237 RS06625
gene id: 199:CCON33237_RS06625
uniprot id: A0A0M4STZ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS00060
gene id: 199:CCON33237_RS00060
uniprot id: A0A0M4TKL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

199:CCON33237 RS01445
gene id: 199:CCON33237_RS01445
uniprot id: A0A0M5MEF7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

199:CCON33237 RS06460
gene id: 199:CCON33237_RS06460
uniprot id: A0A0M4TNE7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

199:CCON33237 RS04250
gene id: 199:CCON33237_RS04250
uniprot id: A0A0M4TLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

199:CCON33237 RS06880
gene id: 199:CCON33237_RS06880
uniprot id: A0A0M5MER0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

199:CCON33237 RS03060
gene id: 199:CCON33237_RS03060
uniprot id: A0A0M3V249
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS08390
gene id: 199:CCON33237_RS08390
uniprot id: A0A0M3V2Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

199:CCON33237 RS01760
gene id: 199:CCON33237_RS01760
uniprot id: A0A0M4STD7
names: Similarity
messages: Belongs to the barstar family.

199:CCON33237 RS02685
gene id: 199:CCON33237_RS02685
uniprot id: A0A0M4SSI0
names: Similarity
messages: Belongs to the LOG family.

199:CCON33237 RS08565
gene id: 199:CCON33237_RS08565
uniprot id: A0A0M4TCR5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

199:CCON33237 RS09280
gene id: 199:CCON33237_RS09280
uniprot id: A0A0M4SPA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multiheme cytochrome c family.
messages: Binds 8 heme c groups covalently per monomer.
messages: Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.
messages: Periplasm
messages: Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.

199:CCON33237 RS02835
gene id: 199:CCON33237_RS02835
uniprot id: A0A0M4SGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS06690
gene id: 199:CCON33237_RS06690
uniprot id: A0A0M3V2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

199:CCON33237 RS08395
gene id: 199:CCON33237_RS08395
uniprot id: A0A0M4SP07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

199:CCON33237 RS06685
gene id: 199:CCON33237_RS06685
uniprot id: A0A0M4TMT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

199:CCON33237 RS06560
gene id: 199:CCON33237_RS06560
uniprot id: A0A0M4SNC0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

199:CCON33237 RS07690
gene id: 199:CCON33237_RS07690
uniprot id: A0A0M4SUD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

199:CCON33237 RS01265
gene id: 199:CCON33237_RS01265
uniprot id: A0A0M4SS31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

199:CCON33237 RS05385
gene id: 199:CCON33237_RS05385
uniprot id: A0A0M4TBM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

199:CCON33237 RS07265
gene id: 199:CCON33237_RS07265
uniprot id: A0A0M5MKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

199:CCON33237 RS00335
gene id: 199:CCON33237_RS00335
uniprot id: A0A0M4TKP4
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS06020
gene id: 199:CCON33237_RS06020
uniprot id: A0A0M4SN58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

199:CCON33237 RS05245
gene id: 199:CCON33237_RS05245
uniprot id: A0A0M4SMV9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

199:CCON33237 RS07335
gene id: 199:CCON33237_RS07335
uniprot id: A0A0M4TNP4
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

199:CCON33237 RS00960
gene id: 199:CCON33237_RS00960
uniprot id: A0A0M3V1X2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS04880
gene id: 199:CCON33237_RS04880
uniprot id: A0A0M4SUJ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

199:CCON33237 RS01660
gene id: 199:CCON33237_RS01660
uniprot id: A0A0M4SLL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS07155
gene id: 199:CCON33237_RS07155
uniprot id: A0A0M4TNM0
names: Similarity
messages: Belongs to the GARS family.

199:CCON33237 RS08270
gene id: 199:CCON33237_RS08270
uniprot id: A0A0M4SNY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

199:CCON33237 RS03375
gene id: 199:CCON33237_RS03375
uniprot id: A0A0M4SM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

199:CCON33237 RS05425
gene id: 199:CCON33237_RS05425
uniprot id: A0A0M4TMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

199:CCON33237 RS04935
gene id: 199:CCON33237_RS04935
uniprot id: A0A0M4TMY6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

199:CCON33237 RS03255
gene id: 199:CCON33237_RS03255
uniprot id: A0A0M4TAU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

199:CCON33237 RS02230
gene id: 199:CCON33237_RS02230
uniprot id: A0A0M5MIH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS08645
gene id: 199:CCON33237_RS08645
uniprot id: A0A0M4TCS2
names: Subcellular Location Annotation
messages: Periplasm

199:CCON33237 RS08340
gene id: 199:CCON33237_RS08340
uniprot id: A0A0M3V2P8
names: Similarity
messages: Belongs to the ModE family.

199:CCON33237 RS08230
gene id: 199:CCON33237_RS08230
uniprot id: A0A0M4TNZ5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

199:CCON33237 RS01270
gene id: 199:CCON33237_RS01270
uniprot id: A0A0M3V1Y2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS09320
gene id: 199:CCON33237_RS09320
uniprot id: A0A0M4SW08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

199:CCON33237 RS08680
gene id: 199:CCON33237_RS08680
uniprot id: A0A0M4TNE9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

199:CCON33237 RS06390
gene id: 199:CCON33237_RS06390
uniprot id: A0A0M5MG75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

199:CCON33237 RS06340
gene id: 199:CCON33237_RS06340
uniprot id: A0A0M4SUY2
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS08580
gene id: 199:CCON33237_RS08580
uniprot id: A0A0M3V2Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

199:CCON33237 RS07030
gene id: 199:CCON33237_RS07030
uniprot id: A0A0M3V2N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

199:CCON33237 RS03520
gene id: 199:CCON33237_RS03520
uniprot id: A0A0M3V2A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

199:CCON33237 RS07075
gene id: 199:CCON33237_RS07075
uniprot id: A0A0M4TC74
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS03840
gene id: 199:CCON33237_RS03840
uniprot id: A0A0M4TLU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

199:CCON33237 RS08670
gene id: 199:CCON33237_RS08670
uniprot id: A0A0M4SVS7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS04495
gene id: 199:CCON33237_RS04495
uniprot id: A0A0M5ME97
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

199:CCON33237 RS06610
gene id: 199:CCON33237_RS06610
uniprot id: A0A0M5MF20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

199:CCON33237 RS00800
gene id: 199:CCON33237_RS00800
uniprot id: A0A0M4SG38
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

199:CCON33237 RS01885
gene id: 199:CCON33237_RS01885
uniprot id: A0A0M3V206
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

199:CCON33237 RS06080
gene id: 199:CCON33237_RS06080
uniprot id: A0A0M4SN67
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS07270
gene id: 199:CCON33237_RS07270
uniprot id: A0A0M3V2K7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

199:CCON33237 RS03775
gene id: 199:CCON33237_RS03775
uniprot id: A0A0M4TLT8
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

199:CCON33237 RS07745
gene id: 199:CCON33237_RS07745
uniprot id: A0A0M4TN54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

199:CCON33237 RS02185
gene id: 199:CCON33237_RS02185
uniprot id: A0A0M4SAK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

199:CCON33237 RS08690
gene id: 199:CCON33237_RS08690
uniprot id: A0A0M3V2Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

199:CCON33237 RS08425
gene id: 199:CCON33237_RS08425
uniprot id: A0A0M4SIK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerH subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

199:CCON33237 RS07405
gene id: 199:CCON33237_RS07405
uniprot id: A0A0M4SI81
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

199:CCON33237 RS02955
gene id: 199:CCON33237_RS02955
uniprot id: A0A0M4SGS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

199:CCON33237 RS01930
gene id: 199:CCON33237_RS01930
uniprot id: A0A0M5MK87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

199:CCON33237 RS07495
gene id: 199:CCON33237_RS07495
uniprot id: A0A0M4SUA6
names: Similarity
messages: Belongs to the MQO family.

199:CCON33237 RS07185
gene id: 199:CCON33237_RS07185
uniprot id: A0A0M4SU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

199:CCON33237 RS06415
gene id: 199:CCON33237_RS06415
uniprot id: A0A0M5MEU3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

199:CCON33237 RS00560
gene id: 199:CCON33237_RS00560
uniprot id: A0A0M4SL79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

199:CCON33237 RS01475
gene id: 199:CCON33237_RS01475
uniprot id: A0A0M4TA68
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS08120
gene id: 199:CCON33237_RS08120
uniprot id: A0A0M5MEK8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

199:CCON33237 RS03035
gene id: 199:CCON33237_RS03035
uniprot id: A0A0M5MEE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

199:CCON33237 RS06445
gene id: 199:CCON33237_RS06445
uniprot id: A0A0M4TBZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS03470
gene id: 199:CCON33237_RS03470
uniprot id: A0A0M3V2A4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

199:CCON33237 RS07230
gene id: 199:CCON33237_RS07230
uniprot id: A0A0M5MIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

199:CCON33237 RS06820
gene id: 199:CCON33237_RS06820
uniprot id: A0A0M4SI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

199:CCON33237 RS03045
gene id: 199:CCON33237_RS03045
uniprot id: A0A0M4SSM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS02350
gene id: 199:CCON33237_RS02350
uniprot id: A0A0M5ME82
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

199:CCON33237 RS06775
gene id: 199:CCON33237_RS06775
uniprot id: A0A0M4SU12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

199:CCON33237 RS09275
gene id: 199:CCON33237_RS09275
uniprot id: A0A0M4SUX0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

199:CCON33237 RS07290
gene id: 199:CCON33237_RS07290
uniprot id: A0A0M3V2P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

199:CCON33237 RS01295
gene id: 199:CCON33237_RS01295
uniprot id: A0A0M5MK65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

199:CCON33237 RS04540
gene id: 199:CCON33237_RS04540
uniprot id: A0A0M4TMT6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

199:CCON33237 RS07350
gene id: 199:CCON33237_RS07350
uniprot id: A0A0M4SVA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

199:CCON33237 RS07760
gene id: 199:CCON33237_RS07760
uniprot id: A0A0M4SNR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

199:CCON33237 RS05955
gene id: 199:CCON33237_RS05955
uniprot id: A0A0M4SN43
names: Similarity
messages: Belongs to the ABC transporter superfamily.

199:CCON33237 RS09330
gene id: 199:CCON33237_RS09330
uniprot id: A0A0M4TNN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

199:CCON33237 RS03205
gene id: 199:CCON33237_RS03205
uniprot id: A0A0M4TMC6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

199:CCON33237 RS04770
gene id: 199:CCON33237_RS04770
uniprot id: A0A0M4SMQ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

199:CCON33237 RS02545
gene id: 199:CCON33237_RS02545
uniprot id: A0A0M5MII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

199:CCON33237 RS00005
gene id: 199:CCON33237_RS00005
uniprot id: A0A0M4SL11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

199:CCON33237 RS01130
gene id: 199:CCON33237_RS01130
uniprot id: A0A0M4TKX9
names: Similarity
messages: Belongs to the UPF0234 family.

199:CCON33237 RS04130
gene id: 199:CCON33237_RS04130
uniprot id: A0A0M4TB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS04430
gene id: 199:CCON33237_RS04430
uniprot id: A0A0M4SUD4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS08755
gene id: 199:CCON33237_RS08755
uniprot id: A0A0M4SP42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

199:CCON33237 RS01555
gene id: 199:CCON33237_RS01555
uniprot id: A0A0M4SGC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

199:CCON33237 RS06395
gene id: 199:CCON33237_RS06395
uniprot id: A0A0M4TNE0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

199:CCON33237 RS07365
gene id: 199:CCON33237_RS07365
uniprot id: A0A0M4SU85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

199:CCON33237 RS01045
gene id: 199:CCON33237_RS01045
uniprot id: A0A0M4TLN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

199:CCON33237 RS07685
gene id: 199:CCON33237_RS07685
uniprot id: A0A0M4TN45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

199:CCON33237 RS02290
gene id: 199:CCON33237_RS02290
uniprot id: A0A0M5MEJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

199:CCON33237 RS08985
gene id: 199:CCON33237_RS08985
uniprot id: A0A0M3V2S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

199:CCON33237 RS02455
gene id: 199:CCON33237_RS02455
uniprot id: A0A0M3V228
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

199:CCON33237 RS04845
gene id: 199:CCON33237_RS04845
uniprot id: A0A0M4SMR2
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS01765
gene id: 199:CCON33237_RS01765
uniprot id: A0A0M5MEG7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

199:CCON33237 RS08410
gene id: 199:CCON33237_RS08410
uniprot id: A0A0M3V2U4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

199:CCON33237 RS02405
gene id: 199:CCON33237_RS02405
uniprot id: A0A0M3V226
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

199:CCON33237 RS03670
gene id: 199:CCON33237_RS03670
uniprot id: A0A0M4TAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

199:CCON33237 RS01240
gene id: 199:CCON33237_RS01240
uniprot id: A0A0M3V218
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

199:CCON33237 RS08550
gene id: 199:CCON33237_RS08550
uniprot id: A0A0M4SUN4
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS08075
gene id: 199:CCON33237_RS08075
uniprot id: A0A0M4SCR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

199:CCON33237 RS02380
gene id: 199:CCON33237_RS02380
uniprot id: A0A0M4SAP0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

199:CCON33237 RS04340
gene id: 199:CCON33237_RS04340
uniprot id: A0A0M5TI99
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

199:CCON33237 RS08010
gene id: 199:CCON33237_RS08010
uniprot id: A0A0M4SNV6
names: Similarity
messages: Belongs to the peptidase A31 family.

199:CCON33237 RS08775
gene id: 199:CCON33237_RS08775
uniprot id: A0A0M4TP52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

199:CCON33237 RS06580
gene id: 199:CCON33237_RS06580
uniprot id: A0A0M5MKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

199:CCON33237 RS03140
gene id: 199:CCON33237_RS03140
uniprot id: A0A0M4TMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

199:CCON33237 RS04555
gene id: 199:CCON33237_RS04555
uniprot id: A0A0M4SUE8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

199:CCON33237 RS08205
gene id: 199:CCON33237_RS08205
uniprot id: A0A0M4SNX8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

199:CCON33237 RS07935
gene id: 199:CCON33237_RS07935
uniprot id: A0A0M4TN77
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

199:CCON33237 RS00545
gene id: 199:CCON33237_RS00545
uniprot id: A0A0M4TKR3
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS07195
gene id: 199:CCON33237_RS07195
uniprot id: A0A0M4SCD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

199:CCON33237 RS03755
gene id: 199:CCON33237_RS03755
uniprot id: A0A0M4SH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

199:CCON33237 RS01675
gene id: 199:CCON33237_RS01675
uniprot id: A0A0M5TIA0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

199:CCON33237 RS08525
gene id: 199:CCON33237_RS08525
uniprot id: A0A0M3V2Q3
names: Similarity
messages: Belongs to the RutC family.

199:CCON33237 RS05335
gene id: 199:CCON33237_RS05335
uniprot id: A0A0M4TN33
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

199:CCON33237 RS02505
gene id: 199:CCON33237_RS02505
uniprot id: A0A0M4SAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

199:CCON33237 RS04530
gene id: 199:CCON33237_RS04530
uniprot id: A0A0M4TBB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

199:CCON33237 RS01750
gene id: 199:CCON33237_RS01750
uniprot id: A0A0M3V239
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

199:CCON33237 RS00050
gene id: 199:CCON33237_RS00050
uniprot id: A0A0M5MEB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

199:CCON33237 RS03190
gene id: 199:CCON33237_RS03190
uniprot id: A0A0M4SAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

199:CCON33237 RS08275
gene id: 199:CCON33237_RS08275
uniprot id: A0A0M4SCT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

199:CCON33237 RS06450
gene id: 199:CCON33237_RS06450
uniprot id: A0A0M5MEI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

199:CCON33237 RS02690
gene id: 199:CCON33237_RS02690
uniprot id: A0A0M4SLZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS01425
gene id: 199:CCON33237_RS01425
uniprot id: A0A0M4TLS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS00135
gene id: 199:CCON33237_RS00135
uniprot id: A0A0M4SL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

199:CCON33237 RS04550
gene id: 199:CCON33237_RS04550
uniprot id: A0A0M3V2A5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

199:CCON33237 RS09315
gene id: 199:CCON33237_RS09315
uniprot id: A0A0M3V2T3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

199:CCON33237 RS08965
gene id: 199:CCON33237_RS08965
uniprot id: A0A0M4SIR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

199:CCON33237 RS01040
gene id: 199:CCON33237_RS01040
uniprot id: A0A0M5TI86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

199:CCON33237 RS01100
gene id: 199:CCON33237_RS01100
uniprot id: A0A0M5MFR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

199:CCON33237 RS07660
gene id: 199:CCON33237_RS07660
uniprot id: A0A0M4TNT3
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS08285
gene id: 199:CCON33237_RS08285
uniprot id: A0A0M5TIB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

199:CCON33237 RS09310
gene id: 199:CCON33237_RS09310
uniprot id: A0A0M4SIV4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS02575
gene id: 199:CCON33237_RS02575
uniprot id: A0A0M4TAK7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

199:CCON33237 RS06365
gene id: 199:CCON33237_RS06365
uniprot id: A0A0M4SN94
names: Similarity
messages: Belongs to the asparaginase 1 family.

199:CCON33237 RS04010
gene id: 199:CCON33237_RS04010
uniprot id: A0A0M4TMM3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

199:CCON33237 RS06705
gene id: 199:CCON33237_RS06705
uniprot id: A0A0M4SC81
names: Similarity
messages: Belongs to the DprA/Smf family.

199:CCON33237 RS03865
gene id: 199:CCON33237_RS03865
uniprot id: A0A0M4TB17
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS04955
gene id: 199:CCON33237_RS04955
uniprot id: A0A0M5MEX5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

199:CCON33237 RS09305
gene id: 199:CCON33237_RS09305
uniprot id: A0A0M4TPB2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

199:CCON33237 RS06620
gene id: 199:CCON33237_RS06620
uniprot id: A0A0M4TMS6
names: Similarity
messages: Belongs to the TlyA family.

199:CCON33237 RS04685
gene id: 199:CCON33237_RS04685
uniprot id: A0A0M4SUG2
names: Similarity
messages: Belongs to the peptidase C40 family.

199:CCON33237 RS06060
gene id: 199:CCON33237_RS06060
uniprot id: A0A0M5MET4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

199:CCON33237 RS06920
gene id: 199:CCON33237_RS06920
uniprot id: A0A0M4SU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

199:CCON33237 RS00775
gene id: 199:CCON33237_RS00775
uniprot id: A0A0M3V203
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

199:CCON33237 RS06400
gene id: 199:CCON33237_RS06400
uniprot id: A0A0M4SHX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

199:CCON33237 RS07520
gene id: 199:CCON33237_RS07520
uniprot id: A0A0M4TCD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

199:CCON33237 RS01835
gene id: 199:CCON33237_RS01835
uniprot id: A0A0M3V204
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS04095
gene id: 199:CCON33237_RS04095
uniprot id: A0A0M3V2C8
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS02395
gene id: 199:CCON33237_RS02395
uniprot id: A0A0M4TM31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

199:CCON33237 RS00520
gene id: 199:CCON33237_RS00520
uniprot id: A0A0M4TLH6
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS01815
gene id: 199:CCON33237_RS01815
uniprot id: A0A0M4TLW3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

199:CCON33237 RS04850
gene id: 199:CCON33237_RS04850
uniprot id: A0A0M4SBK3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

199:CCON33237 RS05080
gene id: 199:CCON33237_RS05080
uniprot id: A0A0M4TN04
names: Similarity
messages: Belongs to the HupF/HypC family.

199:CCON33237 RS02840
gene id: 199:CCON33237_RS02840
uniprot id: A0A0M4STR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS08750
gene id: 199:CCON33237_RS08750
uniprot id: A0A0M4SUQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

199:CCON33237 RS00015
gene id: 199:CCON33237_RS00015
uniprot id: A0A0M4T9P9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

199:CCON33237 RS07245
gene id: 199:CCON33237_RS07245
uniprot id: A0A0M4SU66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS01670
gene id: 199:CCON33237_RS01670
uniprot id: A0A0M4TA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

199:CCON33237 RS07070
gene id: 199:CCON33237_RS07070
uniprot id: A0A0M3V2J9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

199:CCON33237 RS05735
gene id: 199:CCON33237_RS05735
uniprot id: A0A0M3V2J1
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

199:CCON33237 RS02125
gene id: 199:CCON33237_RS02125
uniprot id: A0A0M4SAJ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

199:CCON33237 RS08740
gene id: 199:CCON33237_RS08740
uniprot id: A0A0M3V2R0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

199:CCON33237 RS04545
gene id: 199:CCON33237_RS04545
uniprot id: A0A0M4SHA9
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS00710
gene id: 199:CCON33237_RS00710
uniprot id: A0A0M4SA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS06865
gene id: 199:CCON33237_RS06865
uniprot id: A0A0M3V2N2
names: Similarity
messages: Belongs to the IMPACT family.

199:CCON33237 RS03365
gene id: 199:CCON33237_RS03365
uniprot id: A0A0M4SSR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

199:CCON33237 RS09180
gene id: 199:CCON33237_RS09180
uniprot id: A0A0M4TP97
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

199:CCON33237 RS08855
gene id: 199:CCON33237_RS08855
uniprot id: A0A0M3V2W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

199:CCON33237 RS07770
gene id: 199:CCON33237_RS07770
uniprot id: A0A0M4TCG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS09870
gene id: 199:CCON33237_RS09870
uniprot id: A0A0M3V2C1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

199:CCON33237 RS06090
gene id: 199:CCON33237_RS06090
uniprot id: A0A0M4SC06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

199:CCON33237 RS00750
gene id: 199:CCON33237_RS00750
uniprot id: A0A0M3V1W4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

199:CCON33237 RS02140
gene id: 199:CCON33237_RS02140
uniprot id: A0A0M4TLZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

199:CCON33237 RS07025
gene id: 199:CCON33237_RS07025
uniprot id: A0A0M4SV53
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

199:CCON33237 RS01450
gene id: 199:CCON33237_RS01450
uniprot id: A0A0M4TL17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

199:CCON33237 RS01520
gene id: 199:CCON33237_RS01520
uniprot id: A0A0M3V1Z2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

199:CCON33237 RS08850
gene id: 199:CCON33237_RS08850
uniprot id: A0A0M4SVV4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

199:CCON33237 RS09170
gene id: 199:CCON33237_RS09170
uniprot id: A0A0M4TCY6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

199:CCON33237 RS00830
gene id: 199:CCON33237_RS00830
uniprot id: A0A0M4SRY7
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

199:CCON33237 RS02950
gene id: 199:CCON33237_RS02950
uniprot id: A0A0M4TM93
names: Similarity
messages: Belongs to the YggT family.

199:CCON33237 RS05135
gene id: 199:CCON33237_RS05135
uniprot id: A0A0M5MEE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

199:CCON33237 RS03015
gene id: 199:CCON33237_RS03015
uniprot id: A0A0M4TMA1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

199:CCON33237 RS03965
gene id: 199:CCON33237_RS03965
uniprot id: A0A0M3V282
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS08100
gene id: 199:CCON33237_RS08100
uniprot id: A0A0M4TNY0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

199:CCON33237 RS06805
gene id: 199:CCON33237_RS06805
uniprot id: A0A0M5MEJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

199:CCON33237 RS02010
gene id: 199:CCON33237_RS02010
uniprot id: A0A0M3V250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

199:CCON33237 RS01330
gene id: 199:CCON33237_RS01330
uniprot id: A0A0M4SS39
names: Similarity
messages: Belongs to the UPF0102 family.

199:CCON33237 RS07885
gene id: 199:CCON33237_RS07885
uniprot id: A0A0M4SNT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

199:CCON33237 RS07390
gene id: 199:CCON33237_RS07390
uniprot id: A0A0M3V2Q5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

199:CCON33237 RS03765
gene id: 199:CCON33237_RS03765
uniprot id: A0A0M4SU51
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

199:CCON33237 RS06070
gene id: 199:CCON33237_RS06070
uniprot id: A0A0M4TML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS08835
gene id: 199:CCON33237_RS08835
uniprot id: A0A0M3V2R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

199:CCON33237 RS06040
gene id: 199:CCON33237_RS06040
uniprot id: A0A0M5MG66
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

199:CCON33237 RS08655
gene id: 199:CCON33237_RS08655
uniprot id: A0A0M4TP36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

199:CCON33237 RS05155
gene id: 199:CCON33237_RS05155
uniprot id: A0A0M4SUL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

199:CCON33237 RS00360
gene id: 199:CCON33237_RS00360
uniprot id: A0A0M3V1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

199:CCON33237 RS03295
gene id: 199:CCON33237_RS03295
uniprot id: A0A0M4TLN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

199:CCON33237 RS08080
gene id: 199:CCON33237_RS08080
uniprot id: A0A0M3V2N8
names: Cofactor
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

199:CCON33237 RS07085
gene id: 199:CCON33237_RS07085
uniprot id: A0A0M4TNL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

199:CCON33237 RS02800
gene id: 199:CCON33237_RS02800
uniprot id: A0A0M3V240
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

199:CCON33237 RS08345
gene id: 199:CCON33237_RS08345
uniprot id: A0A0M4TCN9
names: Similarity
messages: Belongs to the MlaA family.

199:CCON33237 RS00555
gene id: 199:CCON33237_RS00555
uniprot id: A0A0M4SRV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

199:CCON33237 RS06490
gene id: 199:CCON33237_RS06490
uniprot id: A0A0M4STY1
names: Similarity
messages: Belongs to the threonine synthase family.

199:CCON33237 RS05450
gene id: 199:CCON33237_RS05450
uniprot id: A0A0M4TBM7
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

199:CCON33237 RS02440
gene id: 199:CCON33237_RS02440
uniprot id: A0A0M4SAP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

199:CCON33237 RS08805
gene id: 199:CCON33237_RS08805
uniprot id: A0A0M3V2V8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

199:CCON33237 RS01745
gene id: 199:CCON33237_RS01745
uniprot id: A0A0M4TLV7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

199:CCON33237 RS06030
gene id: 199:CCON33237_RS06030
uniprot id: A0A0M4TBU6
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS02360
gene id: 199:CCON33237_RS02360
uniprot id: A0A0M4TLD3
names: Similarity
messages: Belongs to the fabD family.

199:CCON33237 RS03410
gene id: 199:CCON33237_RS03410
uniprot id: A0A0M4SGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

199:CCON33237 RS04265
gene id: 199:CCON33237_RS04265
uniprot id: A0A0M3V2D4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

199:CCON33237 RS06910
gene id: 199:CCON33237_RS06910
uniprot id: A0A0M3V2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

199:CCON33237 RS05895
gene id: 199:CCON33237_RS05895
uniprot id: A0A0M4SN34
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

199:CCON33237 RS07555
gene id: 199:CCON33237_RS07555
uniprot id: A0A0M5MIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

199:CCON33237 RS01335
gene id: 199:CCON33237_RS01335
uniprot id: A0A0M4SLH4
names: Similarity
messages: Belongs to the thioredoxin family.

199:CCON33237 RS08035
gene id: 199:CCON33237_RS08035
uniprot id: A0A0M4TNX3
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS02130
gene id: 199:CCON33237_RS02130
uniprot id: A0A0M4TAE6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

199:CCON33237 RS06465
gene id: 199:CCON33237_RS06465
uniprot id: A0A0M4SHX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

199:CCON33237 RS08085
gene id: 199:CCON33237_RS08085
uniprot id: A0A0M4TCK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

199:CCON33237 RS03515
gene id: 199:CCON33237_RS03515
uniprot id: A0A0M4TLQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

199:CCON33237 RS04455
gene id: 199:CCON33237_RS04455
uniprot id: A0A0M4SMK1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

199:CCON33237 RS01325
gene id: 199:CCON33237_RS01325
uniprot id: A0A0M4TL02
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

199:CCON33237 RS03465
gene id: 199:CCON33237_RS03465
uniprot id: A0A0M4SM79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

199:CCON33237 RS04080
gene id: 199:CCON33237_RS04080
uniprot id: A0A0M4TMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

199:CCON33237 RS07675
gene id: 199:CCON33237_RS07675
uniprot id: A0A0M5MET2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

199:CCON33237 RS08810
gene id: 199:CCON33237_RS08810
uniprot id: A0A0M4SUR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

199:CCON33237 RS00095
gene id: 199:CCON33237_RS00095
uniprot id: A0A0M4TLD4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

199:CCON33237 RS03535
gene id: 199:CCON33237_RS03535
uniprot id: A0A0M4SM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dps family.
messages: Cytoplasm

199:CCON33237 RS04145
gene id: 199:CCON33237_RS04145
uniprot id: A0A0M4TMN7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

199:CCON33237 RS04110
gene id: 199:CCON33237_RS04110
uniprot id: A0A0M4ST03
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

199:CCON33237 RS04260
gene id: 199:CCON33237_RS04260
uniprot id: A0A0M4SMH4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

199:CCON33237 RS02960
gene id: 199:CCON33237_RS02960
uniprot id: A0A0M3V246
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

199:CCON33237 RS08760
gene id: 199:CCON33237_RS08760
uniprot id: A0A0M3V2V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

199:CCON33237 RS07225
gene id: 199:CCON33237_RS07225
uniprot id: A0A0M4SV81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS04620
gene id: 199:CCON33237_RS04620
uniprot id: A0A0M3V2E8
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

199:CCON33237 RS05760
gene id: 199:CCON33237_RS05760
uniprot id: A0A0M4STP4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

199:CCON33237 RS04775
gene id: 199:CCON33237_RS04775
uniprot id: A0A0M3V2F4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

199:CCON33237 RS04155
gene id: 199:CCON33237_RS04155
uniprot id: A0A0M4SH65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

199:CCON33237 RS02520
gene id: 199:CCON33237_RS02520
uniprot id: A0A0M5MED5
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS07825
gene id: 199:CCON33237_RS07825
uniprot id: A0A0M4SCM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS07865
gene id: 199:CCON33237_RS07865
uniprot id: A0A0M5MIY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS08975
gene id: 199:CCON33237_RS08975
uniprot id: A0A0M4SVW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

199:CCON33237 RS02855
gene id: 199:CCON33237_RS02855
uniprot id: A0A0M4SSJ7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

199:CCON33237 RS09770
gene id: 199:CCON33237_RS09770
uniprot id: A0A1L9QYU2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

199:CCON33237 RS04715
gene id: 199:CCON33237_RS04715
uniprot id: A0A0M4SBI4
names: Similarity
messages: Belongs to the GSP E family.

199:CCON33237 RS07510
gene id: 199:CCON33237_RS07510
uniprot id: A0A0M4SNN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

199:CCON33237 RS02310
gene id: 199:CCON33237_RS02310
uniprot id: A0A0M4SLU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

199:CCON33237 RS04325
gene id: 199:CCON33237_RS04325
uniprot id: A0A0M4SMI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

199:CCON33237 RS00570
gene id: 199:CCON33237_RS00570
uniprot id: A0A0M4T9W2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

199:CCON33237 RS00580
gene id: 199:CCON33237_RS00580
uniprot id: A0A0M3V1V8
names: Similarity
messages: Belongs to the peptidase C69 family.

199:CCON33237 RS02295
gene id: 199:CCON33237_RS02295
uniprot id: A0A0M4TLC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

199:CCON33237 RS05290
gene id: 199:CCON33237_RS05290
uniprot id: A0A0M3V2D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

199:CCON33237 RS01560
gene id: 199:CCON33237_RS01560
uniprot id: A0A0M4STA4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

199:CCON33237 RS02530
gene id: 199:CCON33237_RS02530
uniprot id: A0A0M3V271
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

199:CCON33237 RS06200
gene id: 199:CCON33237_RS06200
uniprot id: A0A0M4TNC2
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

199:CCON33237 RS09075
gene id: 199:CCON33237_RS09075
uniprot id: A0A0M5MF28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

199:CCON33237 RS01700
gene id: 199:CCON33237_RS01700
uniprot id: A0A0M3V237
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

199:CCON33237 RS03790
gene id: 199:CCON33237_RS03790
uniprot id: A0A0M4SMB8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

199:CCON33237 RS00035
gene id: 199:CCON33237_RS00035
uniprot id: A0A0M4SFV1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

199:CCON33237 RS05395
gene id: 199:CCON33237_RS05395
uniprot id: A0A0M3V2D7
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS04520
gene id: 199:CCON33237_RS04520
uniprot id: A0A0M3V2E4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

199:CCON33237 RS07995
gene id: 199:CCON33237_RS07995
uniprot id: A0A0M4TN84
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

199:CCON33237 RS04870
gene id: 199:CCON33237_RS04870
uniprot id: A0A0M4TMY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

199:CCON33237 RS01880
gene id: 199:CCON33237_RS01880
uniprot id: A0A0M4SGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS08535
gene id: 199:CCON33237_RS08535
uniprot id: A0A0M5MJ06
names: Similarity
messages: Belongs to the class-I fumarase family.

199:CCON33237 RS08040
gene id: 199:CCON33237_RS08040
uniprot id: A0A0M4SIF6
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS05370
gene id: 199:CCON33237_RS05370
uniprot id: A0A0M4STJ9
names: Function
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.

199:CCON33237 RS07215
gene id: 199:CCON33237_RS07215
uniprot id: A0A0M4SI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS07820
gene id: 199:CCON33237_RS07820
uniprot id: A0A0M4SNS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS07700
gene id: 199:CCON33237_RS07700
uniprot id: A0A0M3V2R7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

199:CCON33237 RS01035
gene id: 199:CCON33237_RS01035
uniprot id: A0A0M3V211
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

199:CCON33237 RS08115
gene id: 199:CCON33237_RS08115
uniprot id: A0A0M4SVL5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

199:CCON33237 RS05075
gene id: 199:CCON33237_RS05075
uniprot id: A0A0M5MG38
names: Similarity
messages: Belongs to the HypD family.

199:CCON33237 RS03805
gene id: 199:CCON33237_RS03805
uniprot id: A0A0M5MEB3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

199:CCON33237 RS09070
gene id: 199:CCON33237_RS09070
uniprot id: A0A0M4SVX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS02255
gene id: 199:CCON33237_RS02255
uniprot id: A0A0M3V221
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

199:CCON33237 RS02655
gene id: 199:CCON33237_RS02655
uniprot id: A0A0M4SGP6
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

199:CCON33237 RS02495
gene id: 199:CCON33237_RS02495
uniprot id: A0A0M4SSF3
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS05950
gene id: 199:CCON33237_RS05950
uniprot id: A0A0M4STR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS00785
gene id: 199:CCON33237_RS00785
uniprot id: A0A0M4T9Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

199:CCON33237 RS07180
gene id: 199:CCON33237_RS07180
uniprot id: A0A0M4TMY5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

199:CCON33237 RS02250
gene id: 199:CCON33237_RS02250
uniprot id: A0A0M4SAL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

199:CCON33237 RS00890
gene id: 199:CCON33237_RS00890
uniprot id: A0A0M4SRZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

199:CCON33237 RS06285
gene id: 199:CCON33237_RS06285
uniprot id: A0A0M4TMN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

199:CCON33237 RS04470
gene id: 199:CCON33237_RS04470
uniprot id: A0A0M3V2E2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

199:CCON33237 RS01350
gene id: 199:CCON33237_RS01350
uniprot id: A0A0M4TA52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

199:CCON33237 RS08280
gene id: 199:CCON33237_RS08280
uniprot id: A0A0M4TCN1
names: Cofactor
names: Similarity
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

199:CCON33237 RS05790
gene id: 199:CCON33237_RS05790
uniprot id: A0A0M5MEG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

199:CCON33237 RS06740
gene id: 199:CCON33237_RS06740
uniprot id: A0A0M3V2M8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS01465
gene id: 199:CCON33237_RS01465
uniprot id: A0A0M4SAB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

199:CCON33237 RS05910
gene id: 199:CCON33237_RS05910
uniprot id: A0A0M5MKK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

199:CCON33237 RS02245
gene id: 199:CCON33237_RS02245
uniprot id: A0A0M4SLT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

199:CCON33237 RS05240
gene id: 199:CCON33237_RS05240
uniprot id: A0A0M3V2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

199:CCON33237 RS02235
gene id: 199:CCON33237_RS02235
uniprot id: A0A0M4TLB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

199:CCON33237 RS06105
gene id: 199:CCON33237_RS06105
uniprot id: A0A0M4TNB6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS01395
gene id: 199:CCON33237_RS01395
uniprot id: A0A0M4SS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

199:CCON33237 RS09060
gene id: 199:CCON33237_RS09060
uniprot id: A0A0M4SIS5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS05125
gene id: 199:CCON33237_RS05125
uniprot id: A0A0M4SBN3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

199:CCON33237 RS06655
gene id: 199:CCON33237_RS06655
uniprot id: A0A0M5TID3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

199:CCON33237 RS04190
gene id: 199:CCON33237_RS04190
uniprot id: A0A0M4ST12
names: Similarity
messages: Belongs to the bacterial secretin family.

199:CCON33237 RS03690
gene id: 199:CCON33237_RS03690
uniprot id: A0A0M4SH11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

199:CCON33237 RS04345
gene id: 199:CCON33237_RS04345
uniprot id: A0A0M3V296
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

199:CCON33237 RS02910
gene id: 199:CCON33237_RS02910
uniprot id: A0A0M3V244
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

199:CCON33237 RS06380
gene id: 199:CCON33237_RS06380
uniprot id: A0A0M4TBY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

199:CCON33237 RS03505
gene id: 199:CCON33237_RS03505
uniprot id: A0A0M4SU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

199:CCON33237 RS07925
gene id: 199:CCON33237_RS07925
uniprot id: A0A0M5MF60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

199:CCON33237 RS02625
gene id: 199:CCON33237_RS02625
uniprot id: A0A0M4SLY3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

199:CCON33237 RS06965
gene id: 199:CCON33237_RS06965
uniprot id: A0A0M4SV45
names: Similarity
messages: Belongs to the peptidase M16 family.

199:CCON33237 RS03890
gene id: 199:CCON33237_RS03890
uniprot id: A0A0M4SU69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

199:CCON33237 RS07035
gene id: 199:CCON33237_RS07035
uniprot id: A0A0M5MER2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS03120
gene id: 199:CCON33237_RS03120
uniprot id: A0A0M4SAY5
names: Similarity
messages: Belongs to the peptidase M16 family.

199:CCON33237 RS03475
gene id: 199:CCON33237_RS03475
uniprot id: A0A0M4SB24
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

199:CCON33237 RS08860
gene id: 199:CCON33237_RS08860
uniprot id: A0A0M5MJ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

199:CCON33237 RS06025
gene id: 199:CCON33237_RS06025
uniprot id: A0A0M4SBZ4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

199:CCON33237 RS00130
gene id: 199:CCON33237_RS00130
uniprot id: A0A0M3V1U2
names: Similarity
messages: Belongs to the peptidase S51 family.

199:CCON33237 RS02845
gene id: 199:CCON33237_RS02845
uniprot id: A0A0M5ME49
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

199:CCON33237 RS05555
gene id: 199:CCON33237_RS05555
uniprot id: A0A0M4SN00
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

199:CCON33237 RS07380
gene id: 199:CCON33237_RS07380
uniprot id: A0A0M4SCG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

199:CCON33237 RS06440
gene id: 199:CCON33237_RS06440
uniprot id: A0A0M4SC44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

199:CCON33237 RS01300
gene id: 199:CCON33237_RS01300
uniprot id: A0A0M4TLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

199:CCON33237 RS08770
gene id: 199:CCON33237_RS08770
uniprot id: A0A0M5MER3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

199:CCON33237 RS04905
gene id: 199:CCON33237_RS04905
uniprot id: A0A0M4STE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

199:CCON33237 RS07300
gene id: 199:CCON33237_RS07300
uniprot id: A0A0M4TN00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

199:CCON33237 RS01820
gene id: 199:CCON33237_RS01820
uniprot id: A0A0M4SGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

199:CCON33237 RS08130
gene id: 199:CCON33237_RS08130
uniprot id: A0A0M4SUJ0
names: Similarity
messages: Belongs to the UPF0751 family.

199:CCON33237 RS00790
gene id: 199:CCON33237_RS00790
uniprot id: A0A0M5ME32
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

199:CCON33237 RS08320
gene id: 199:CCON33237_RS08320
uniprot id: A0A0M4TNB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

199:CCON33237 RS00855
gene id: 199:CCON33237_RS00855
uniprot id: A0A0M3V1W8
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS02480
gene id: 199:CCON33237_RS02480
uniprot id: A0A0M3V269
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

199:CCON33237 RS05405
gene id: 199:CCON33237_RS05405
uniprot id: A0A0M4SHL6
names: Similarity
messages: Belongs to the peptidase M16 family.

199:CCON33237 RS07385
gene id: 199:CCON33237_RS07385
uniprot id: A0A0M4TCB8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

199:CCON33237 RS02355
gene id: 199:CCON33237_RS02355
uniprot id: A0A0M3V225
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

199:CCON33237 RS05255
gene id: 199:CCON33237_RS05255
uniprot id: A0A0M4TBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS05150
gene id: 199:CCON33237_RS05150
uniprot id: A0A0M4SHI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

199:CCON33237 RS06235
gene id: 199:CCON33237_RS06235
uniprot id: A0A0M4SN80
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

199:CCON33237 RS00740
gene id: 199:CCON33237_RS00740
uniprot id: A0A0M4ST13
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS06665
gene id: 199:CCON33237_RS06665
uniprot id: A0A0M4SI03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

199:CCON33237 RS03260
gene id: 199:CCON33237_RS03260
uniprot id: A0A0M5MKC9
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS03740
gene id: 199:CCON33237_RS03740
uniprot id: A0A0M4TB01
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS06095
gene id: 199:CCON33237_RS06095
uniprot id: A0A0M4TBV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

199:CCON33237 RS01050
gene id: 199:CCON33237_RS01050
uniprot id: A0A0M4SG67
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS03640
gene id: 199:CCON33237_RS03640
uniprot id: A0A0M5MEN7
names: Similarity
messages: Belongs to the AdoMet synthase family.

199:CCON33237 RS06890
gene id: 199:CCON33237_RS06890
uniprot id: A0A0M4SI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS09090
gene id: 199:CCON33237_RS09090
uniprot id: A0A0M4SUU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS05740
gene id: 199:CCON33237_RS05740
uniprot id: A0A0M4SHQ0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

199:CCON33237 RS06855
gene id: 199:CCON33237_RS06855
uniprot id: A0A0M4SC95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

199:CCON33237 RS07275
gene id: 199:CCON33237_RS07275
uniprot id: A0A0M4TNN4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

199:CCON33237 RS01360
gene id: 199:CCON33237_RS01360
uniprot id: A0A0M4TLR4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS03655
gene id: 199:CCON33237_RS03655
uniprot id: A0A0M3V270
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

199:CCON33237 RS00965
gene id: 199:CCON33237_RS00965
uniprot id: A0A0M4SLD0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

199:CCON33237 RS01590
gene id: 199:CCON33237_RS01590
uniprot id: A0A0M3V233
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

199:CCON33237 RS04645
gene id: 199:CCON33237_RS04645
uniprot id: A0A0M4SBH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS00265
gene id: 199:CCON33237_RS00265
uniprot id: A0A0M5MED3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

199:CCON33237 RS07515
gene id: 199:CCON33237_RS07515
uniprot id: A0A0M4SCI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS05890
gene id: 199:CCON33237_RS05890
uniprot id: A0A0M4STR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

199:CCON33237 RS02315
gene id: 199:CCON33237_RS02315
uniprot id: A0A0M4SAM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

199:CCON33237 RS08045
gene id: 199:CCON33237_RS08045
uniprot id: A0A0M4SVK1
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS00950
gene id: 199:CCON33237_RS00950
uniprot id: A0A0M4TKW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

199:CCON33237 RS02345
gene id: 199:CCON33237_RS02345
uniprot id: A0A0M4STK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

199:CCON33237 RS05455
gene id: 199:CCON33237_RS05455
uniprot id: A0A0M5MEF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

199:CCON33237 RS01380
gene id: 199:CCON33237_RS01380
uniprot id: A0A0M5ME51
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

199:CCON33237 RS00935
gene id: 199:CCON33237_RS00935
uniprot id: A0A0M4SG60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

199:CCON33237 RS01785
gene id: 199:CCON33237_RS01785
uniprot id: A0A0M4SLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

199:CCON33237 RS07055
gene id: 199:CCON33237_RS07055
uniprot id: A0A0M4SCC1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS08920
gene id: 199:CCON33237_RS08920
uniprot id: A0A0M4TNI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

199:CCON33237 RS08825
gene id: 199:CCON33237_RS08825
uniprot id: A0A0M4TCU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

199:CCON33237 RS04680
gene id: 199:CCON33237_RS04680
uniprot id: A0A0M4SHC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS07250
gene id: 199:CCON33237_RS07250
uniprot id: A0A0M4SNJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

199:CCON33237 RS04035
gene id: 199:CCON33237_RS04035
uniprot id: A0A0M4TLW9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

199:CCON33237 RS06715
gene id: 199:CCON33237_RS06715
uniprot id: A0A0M5MG83
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS04865
gene id: 199:CCON33237_RS04865
uniprot id: A0A0M3V2B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

199:CCON33237 RS07765
gene id: 199:CCON33237_RS07765
uniprot id: A0A0M4SCM1
names: Similarity
messages: Belongs to the TrpF family.

199:CCON33237 RS02770
gene id: 199:CCON33237_RS02770
uniprot id: A0A0M3V279
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

199:CCON33237 RS08840
gene id: 199:CCON33237_RS08840
uniprot id: A0A0M4TP60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

199:CCON33237 RS03235
gene id: 199:CCON33237_RS03235
uniprot id: A0A0M3V297
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

199:CCON33237 RS06895
gene id: 199:CCON33237_RS06895
uniprot id: A0A0M4SV37
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

199:CCON33237 RS03630
gene id: 199:CCON33237_RS03630
uniprot id: A0A0M4SH03
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

199:CCON33237 RS09210
gene id: 199:CCON33237_RS09210
uniprot id: A0A0M4SUW2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

199:CCON33237 RS07755
gene id: 199:CCON33237_RS07755
uniprot id: A0A0M4SUD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

199:CCON33237 RS04370
gene id: 199:CCON33237_RS04370
uniprot id: A0A0M5MEI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

199:CCON33237 RS03610
gene id: 199:CCON33237_RS03610
uniprot id: A0A0M4TAY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

199:CCON33237 RS01275
gene id: 199:CCON33237_RS01275
uniprot id: A0A0M4SLG6
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

199:CCON33237 RS04360
gene id: 199:CCON33237_RS04360
uniprot id: A0A0M4SUC7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

199:CCON33237 RS01065
gene id: 199:CCON33237_RS01065
uniprot id: A0A0M3V1X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

199:CCON33237 RS00600
gene id: 199:CCON33237_RS00600
uniprot id: A0A0M3V1Z7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS07830
gene id: 199:CCON33237_RS07830
uniprot id: A0A0M3V2M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS05250
gene id: 199:CCON33237_RS05250
uniprot id: A0A0M4SBQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

199:CCON33237 RS00120
gene id: 199:CCON33237_RS00120
uniprot id: A0A0M4TKM1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

199:CCON33237 RS06990
gene id: 199:CCON33237_RS06990
uniprot id: A0A0M4SNG4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

199:CCON33237 RS08675
gene id: 199:CCON33237_RS08675
uniprot id: A0A0M5MEW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

199:CCON33237 RS05045
gene id: 199:CCON33237_RS05045
uniprot id: A0A0M4TM97
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

199:CCON33237 RS09215
gene id: 199:CCON33237_RS09215
uniprot id: A0A0M3V2S9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

199:CCON33237 RS00625
gene id: 199:CCON33237_RS00625
uniprot id: A0A0M4SA19
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

199:CCON33237 RS07460
gene id: 199:CCON33237_RS07460
uniprot id: A0A0M4TNR1
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

199:CCON33237 RS04930
gene id: 199:CCON33237_RS04930
uniprot id: A0A0M5MKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

199:CCON33237 RS09240
gene id: 199:CCON33237_RS09240
uniprot id: A0A0M5MKT9
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS03195
gene id: 199:CCON33237_RS03195
uniprot id: A0A0M4TAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

199:CCON33237 RS08450
gene id: 199:CCON33237_RS08450
uniprot id: A0A0M4SUM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

199:CCON33237 RS08105
gene id: 199:CCON33237_RS08105
uniprot id: A0A0M3V2T2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

199:CCON33237 RS04945
gene id: 199:CCON33237_RS04945
uniprot id: A0A0M4SHG4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

199:CCON33237 RS06270
gene id: 199:CCON33237_RS06270
uniprot id: A0A0M4SHV8
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

199:CCON33237 RS07540
gene id: 199:CCON33237_RS07540
uniprot id: A0A0M4SI96
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

199:CCON33237 RS00745
gene id: 199:CCON33237_RS00745
uniprot id: A0A0M5MED7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

199:CCON33237 RS07845
gene id: 199:CCON33237_RS07845
uniprot id: A0A0M4TNV7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

199:CCON33237 RS01725
gene id: 199:CCON33237_RS01725
uniprot id: A0A0M4SAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

199:CCON33237 RS03820
gene id: 199:CCON33237_RS03820
uniprot id: A0A0M4SH23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

199:CCON33237 RS00910
gene id: 199:CCON33237_RS00910
uniprot id: A0A0M3V1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

199:CCON33237 RS07415
gene id: 199:CCON33237_RS07415
uniprot id: A0A0M5MEX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

199:CCON33237 RS04755
gene id: 199:CCON33237_RS04755
uniprot id: A0A0M3V2B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

199:CCON33237 RS04640
gene id: 199:CCON33237_RS04640
uniprot id: A0A0M4SMM9
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

199:CCON33237 RS05805
gene id: 199:CCON33237_RS05805
uniprot id: A0A0M4SUS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS02320
gene id: 199:CCON33237_RS02320
uniprot id: A0A0M4TAH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

199:CCON33237 RS02420
gene id: 199:CCON33237_RS02420
uniprot id: A0A0M4TLE1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

199:CCON33237 RS09020
gene id: 199:CCON33237_RS09020
uniprot id: A0A0M4SUT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

199:CCON33237 RS03620
gene id: 199:CCON33237_RS03620
uniprot id: A0A0M4TMH1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

199:CCON33237 RS04505
gene id: 199:CCON33237_RS04505
uniprot id: A0A0M4TM29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

199:CCON33237 RS06530
gene id: 199:CCON33237_RS06530
uniprot id: A0A0M4SHY7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS05375
gene id: 199:CCON33237_RS05375
uniprot id: A0A0M4SMX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

199:CCON33237 RS05975
gene id: 199:CCON33237_RS05975
uniprot id: A0A0M5TIB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

199:CCON33237 RS01580
gene id: 199:CCON33237_RS01580
uniprot id: A0A0M4SS70
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS07890
gene id: 199:CCON33237_RS07890
uniprot id: A0A0M4SCP0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

199:CCON33237 RS07920
gene id: 199:CCON33237_RS07920
uniprot id: A0A0M4SVI2
names: Similarity
messages: Belongs to the UPF0167 family.

199:CCON33237 RS04515
gene id: 199:CCON33237_RS04515
uniprot id: A0A0M4SML0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

199:CCON33237 RS08545
gene id: 199:CCON33237_RS08545
uniprot id: A0A0M3V2U8
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS05915
gene id: 199:CCON33237_RS05915
uniprot id: A0A0M3V2F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

199:CCON33237 RS01060
gene id: 199:CCON33237_RS01060
uniprot id: A0A0M5ME41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

199:CCON33237 RS01160
gene id: 199:CCON33237_RS01160
uniprot id: A0A0M5ME42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

199:CCON33237 RS03230
gene id: 199:CCON33237_RS03230
uniprot id: A0A0M4TLN0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

199:CCON33237 RS02300
gene id: 199:CCON33237_RS02300
uniprot id: A0A0M4SSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

199:CCON33237 RS08895
gene id: 199:CCON33237_RS08895
uniprot id: A0A0M5MKS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

199:CCON33237 RS06015
gene id: 199:CCON33237_RS06015
uniprot id: A0A0M3V2G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

199:CCON33237 RS00065
gene id: 199:CCON33237_RS00065
uniprot id: A0A0M4SRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

199:CCON33237 RS02175
gene id: 199:CCON33237_RS02175
uniprot id: A0A0M4SSB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

199:CCON33237 RS02445
gene id: 199:CCON33237_RS02445
uniprot id: A0A0M4TAI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

199:CCON33237 RS01650
gene id: 199:CCON33237_RS01650
uniprot id: A0A0M3V235
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

199:CCON33237 RS03385
gene id: 199:CCON33237_RS03385
uniprot id: A0A0M4TAV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

199:CCON33237 RS03025
gene id: 199:CCON33237_RS03025
uniprot id: A0A0M4STW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS02265
gene id: 199:CCON33237_RS02265
uniprot id: A0A0M5MKA0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

199:CCON33237 RS03760
gene id: 199:CCON33237_RS03760
uniprot id: A0A0M3V274
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

199:CCON33237 RS07565
gene id: 199:CCON33237_RS07565
uniprot id: A0A0M4SUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

199:CCON33237 RS05105
gene id: 199:CCON33237_RS05105
uniprot id: A0A0M4TMA5
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

199:CCON33237 RS00110
gene id: 199:CCON33237_RS00110
uniprot id: A0A0M4SSU1
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

199:CCON33237 RS04305
gene id: 199:CCON33237_RS04305
uniprot id: A0A0M5MEV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS04765
gene id: 199:CCON33237_RS04765
uniprot id: A0A0M4ST96
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

199:CCON33237 RS05310
gene id: 199:CCON33237_RS05310
uniprot id: A0A0M3V2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

199:CCON33237 RS04990
gene id: 199:CCON33237_RS04990
uniprot id: A0A0M3V2G2
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

199:CCON33237 RS03815
gene id: 199:CCON33237_RS03815
uniprot id: A0A0M4TMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

199:CCON33237 RS09165
gene id: 199:CCON33237_RS09165
uniprot id: A0A0M3V2S6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

199:CCON33237 RS03220
gene id: 199:CCON33237_RS03220
uniprot id: A0A0M4STZ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

199:CCON33237 RS07870
gene id: 199:CCON33237_RS07870
uniprot id: A0A0M4TN67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

199:CCON33237 RS03580
gene id: 199:CCON33237_RS03580
uniprot id: A0A0M5MIK9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

199:CCON33237 RS03600
gene id: 199:CCON33237_RS03600
uniprot id: A0A1X4MK04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

199:CCON33237 RS00010
gene id: 199:CCON33237_RS00010
uniprot id: A0A0M4S9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

199:CCON33237 RS03885
gene id: 199:CCON33237_RS03885
uniprot id: A0A0M4SH33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

199:CCON33237 RS08335
gene id: 199:CCON33237_RS08335
uniprot id: A0A0M4SCU8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

199:CCON33237 RS02465
gene id: 199:CCON33237_RS02465
uniprot id: A0A0M4SGM3
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

199:CCON33237 RS08355
gene id: 199:CCON33237_RS08355
uniprot id: A0A0M4TP10
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS07205
gene id: 199:CCON33237_RS07205
uniprot id: A0A0M5MER9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS01430
gene id: 199:CCON33237_RS01430
uniprot id: A0A0M4SGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

199:CCON33237 RS06970
gene id: 199:CCON33237_RS06970
uniprot id: A0A0M5MF29
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS07260
gene id: 199:CCON33237_RS07260
uniprot id: A0A0M4TC98
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

199:CCON33237 RS06405
gene id: 199:CCON33237_RS06405
uniprot id: A0A0M3V2H5
names: Subcellular Location Annotation
messages: Secreted

199:CCON33237 RS05840
gene id: 199:CCON33237_RS05840
uniprot id: A0A0M4SBX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS04975
gene id: 199:CCON33237_RS04975
uniprot id: A0A0M4SMS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

199:CCON33237 RS07005
gene id: 199:CCON33237_RS07005
uniprot id: A0A0M5TIA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

199:CCON33237 RS06320
gene id: 199:CCON33237_RS06320
uniprot id: A0A0M3V2L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS01175
gene id: 199:CCON33237_RS01175
uniprot id: A0A0M4TLP6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

199:CCON33237 RS04065
gene id: 199:CCON33237_RS04065
uniprot id: A0A0M4TB45
names: Similarity
messages: Belongs to the UbiD family.

199:CCON33237 RS03860
gene id: 199:CCON33237_RS03860
uniprot id: A0A0M3V278
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

199:CCON33237 RS08935
gene id: 199:CCON33237_RS08935
uniprot id: A0A0M4SP59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

199:CCON33237 RS05965
gene id: 199:CCON33237_RS05965
uniprot id: A0A0M3V2F9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

199:CCON33237 RS07020
gene id: 199:CCON33237_RS07020
uniprot id: A0A0M4SI37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS07045
gene id: 199:CCON33237_RS07045
uniprot id: A0A0M4SU47
names: Subcellular Location Annotation
names: Subunit
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane

199:CCON33237 RS00925
gene id: 199:CCON33237_RS00925
uniprot id: A0A0M4TLM4
names: Subcellular Location Annotation
messages: Cytoplasm

199:CCON33237 RS07715
gene id: 199:CCON33237_RS07715
uniprot id: A0A0M5MGB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

199:CCON33237 RS05400
gene id: 199:CCON33237_RS05400
uniprot id: A0A0M4TN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

199:CCON33237 RS09200
gene id: 199:CCON33237_RS09200
uniprot id: A0A0M5MJ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

199:CCON33237 RS08185
gene id: 199:CCON33237_RS08185
uniprot id: A0A0M5MIZ6
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

199:CCON33237 RS01865
gene id: 199:CCON33237_RS01865
uniprot id: A0A0M4TAB3
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

199:CCON33237 RS06215
gene id: 199:CCON33237_RS06215
uniprot id: A0A0M3V2K8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

199:CCON33237 RS01290
gene id: 199:CCON33237_RS01290
uniprot id: A0A0M3V220
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

199:CCON33237 RS04840
gene id: 199:CCON33237_RS04840
uniprot id: A0A0M4STE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS06220
gene id: 199:CCON33237_RS06220
uniprot id: A0A0M5MIT9
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS04675
gene id: 199:CCON33237_RS04675
uniprot id: A0A0M3V2F0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

199:CCON33237 RS07135
gene id: 199:CCON33237_RS07135
uniprot id: A0A0M4SCD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

199:CCON33237 RS03485
gene id: 199:CCON33237_RS03485
uniprot id: A0A0M5MEA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

199:CCON33237 RS03650
gene id: 199:CCON33237_RS03650
uniprot id: A0A0M4SSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

199:CCON33237 RS01755
gene id: 199:CCON33237_RS01755
uniprot id: A0A0M4SGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

199:CCON33237 RS01090
gene id: 199:CCON33237_RS01090
uniprot id: A0A0M4SA65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

199:CCON33237 RS02585
gene id: 199:CCON33237_RS02585
uniprot id: A0A0M5MKA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

199:CCON33237 RS05130
gene id: 199:CCON33237_RS05130
uniprot id: A0A0M4TBJ1
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

199:CCON33237 RS00100
gene id: 199:CCON33237_RS00100
uniprot id: A0A0M3V1X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

199:CCON33237 RS02145
gene id: 199:CCON33237_RS02145
uniprot id: A0A0M4SGJ0
names: Similarity
messages: Belongs to the XseB family.

199:CCON33237 RS02675
gene id: 199:CCON33237_RS02675
uniprot id: A0A0M4TLH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

199:CCON33237 RS06210
gene id: 199:CCON33237_RS06210
uniprot id: A0A0M4SUW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

199:CCON33237 RS07340
gene id: 199:CCON33237_RS07340
uniprot id: A0A0M3V2Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

199:CCON33237 RS07305
gene id: 199:CCON33237_RS07305
uniprot id: A0A0M4SU76
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

199:CCON33237 RS01840
gene id: 199:CCON33237_RS01840
uniprot id: A0A0M4TL60
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS00815
gene id: 199:CCON33237_RS00815
uniprot id: A0A0M5MDZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS03115
gene id: 199:CCON33237_RS03115
uniprot id: A0A0M4SM38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

199:CCON33237 RS05145
gene id: 199:CCON33237_RS05145
uniprot id: A0A0M4TN12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

199:CCON33237 RS07470
gene id: 199:CCON33237_RS07470
uniprot id: A0A0M3V2L6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

199:CCON33237 RS02875
gene id: 199:CCON33237_RS02875
uniprot id: A0A0M4TAP2
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

199:CCON33237 RS06555
gene id: 199:CCON33237_RS06555
uniprot id: A0A0M3V2I0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS05315
gene id: 199:CCON33237_RS05315
uniprot id: A0A0M4SBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

199:CCON33237 RS03725
gene id: 199:CCON33237_RS03725
uniprot id: A0A0M4SMA9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

199:CCON33237 RS04040
gene id: 199:CCON33237_RS04040
uniprot id: A0A0M3V2C6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

199:CCON33237 RS07570
gene id: 199:CCON33237_RS07570
uniprot id: A0A0M4SNP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

199:CCON33237 RS02135
gene id: 199:CCON33237_RS02135
uniprot id: A0A0M5ME72
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

199:CCON33237 RS08960
gene id: 199:CCON33237_RS08960
uniprot id: A0A0M4TP76
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

199:CCON33237 RS07395
gene id: 199:CCON33237_RS07395
uniprot id: A0A0M5MGA3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

199:CCON33237 RS08745
gene id: 199:CCON33237_RS08745
uniprot id: A0A0M4TNF8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

199:CCON33237 RS03280
gene id: 199:CCON33237_RS03280
uniprot id: A0A0M4SU00
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

199:CCON33237 RS06265
gene id: 199:CCON33237_RS06265
uniprot id: A0A0M3V2L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

199:CCON33237 RS00665
gene id: 199:CCON33237_RS00665
uniprot id: A0A0M5ME28
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

199:CCON33237 RS07530
gene id: 199:CCON33237_RS07530
uniprot id: A0A0M3V2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

199:CCON33237 RS04655
gene id: 199:CCON33237_RS04655
uniprot id: A0A0M4TBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

199:CCON33237 RS07835
gene id: 199:CCON33237_RS07835
uniprot id: A0A0M4TCH7
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS02890
gene id: 199:CCON33237_RS02890
uniprot id: A0A0M4TM84
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

199:CCON33237 RS05410
gene id: 199:CCON33237_RS05410
uniprot id: A0A1L9R2L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

199:CCON33237 RS04045
gene id: 199:CCON33237_RS04045
uniprot id: A0A0M4SSZ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

199:CCON33237 RS07790
gene id: 199:CCON33237_RS07790
uniprot id: A0A0M4SIC9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

199:CCON33237 RS06565
gene id: 199:CCON33237_RS06565
uniprot id: A0A0M4SC65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

199:CCON33237 RS05775
gene id: 199:CCON33237_RS05775
uniprot id: A0A0M4SBW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

199:CCON33237 RS03560
gene id: 199:CCON33237_RS03560
uniprot id: A0A0M4TMG5
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS05945
gene id: 199:CCON33237_RS05945
uniprot id: A0A0M4TMJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS03405
gene id: 199:CCON33237_RS03405
uniprot id: A0A0M4TMF2
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS04760
gene id: 199:CCON33237_RS04760
uniprot id: A0A0M4TM70
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

199:CCON33237 RS01585
gene id: 199:CCON33237_RS01585
uniprot id: A0A0M4SLK8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

199:CCON33237 RS03380
gene id: 199:CCON33237_RS03380
uniprot id: A0A0M4SB17
names: Similarity
messages: Belongs to the UPF0763 family.

199:CCON33237 RS06675
gene id: 199:CCON33237_RS06675
uniprot id: A0A0M4SV21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

199:CCON33237 RS05070
gene id: 199:CCON33237_RS05070
uniprot id: A0A0M4TBI3
names: Similarity
messages: Belongs to the HypE family.

199:CCON33237 RS06745
gene id: 199:CCON33237_RS06745
uniprot id: A0A0M5MEV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

199:CCON33237 RS09190
gene id: 199:CCON33237_RS09190
uniprot id: A0A0M4SIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

199:CCON33237 RS06770
gene id: 199:CCON33237_RS06770
uniprot id: A0A0M4TMU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

199:CCON33237 RS02970
gene id: 199:CCON33237_RS02970
uniprot id: A0A0M5MEL8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

199:CCON33237 RS00955
gene id: 199:CCON33237_RS00955
uniprot id: A0A0M4SS01
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

199:CCON33237 RS01235
gene id: 199:CCON33237_RS01235
uniprot id: A0A0M4TLQ1
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

199:CCON33237 RS05420
gene id: 199:CCON33237_RS05420
uniprot id: A0A0M5MER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

199:CCON33237 RS01900
gene id: 199:CCON33237_RS01900
uniprot id: A0A0M4TL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

199:CCON33237 RS01870
gene id: 199:CCON33237_RS01870
uniprot id: A0A0M5ME69
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS08725
gene id: 199:CCON33237_RS08725
uniprot id: A0A0M4SIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

199:CCON33237 RS06510
gene id: 199:CCON33237_RS06510
uniprot id: A0A0M4TC04
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS07355
gene id: 199:CCON33237_RS07355
uniprot id: A0A0M5MES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

199:CCON33237 RS01910
gene id: 199:CCON33237_RS01910
uniprot id: A0A0M4SS94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS02640
gene id: 199:CCON33237_RS02640
uniprot id: A0A0M4TAL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

199:CCON33237 RS07550
gene id: 199:CCON33237_RS07550
uniprot id: A0A0M3V2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

199:CCON33237 RS00585
gene id: 199:CCON33237_RS00585
uniprot id: A0A0M4TLI4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

199:CCON33237 RS05065
gene id: 199:CCON33237_RS05065
uniprot id: A0A0M4SBM5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

199:CCON33237 RS05750
gene id: 199:CCON33237_RS05750
uniprot id: A0A0M5MES5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

199:CCON33237 RS00645
gene id: 199:CCON33237_RS00645
uniprot id: A0A0M4TLJ5
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS08880
gene id: 199:CCON33237_RS08880
uniprot id: A0A0M4SD14
names: Similarity
messages: Belongs to the HsdR family.
messages: Belongs to the N(4)/N(6)-methyltransferase family.

199:CCON33237 RS06375
gene id: 199:CCON33237_RS06375
uniprot id: A0A0M4SC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

199:CCON33237 RS00105
gene id: 199:CCON33237_RS00105
uniprot id: A0A0M4SFV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

199:CCON33237 RS08845
gene id: 199:CCON33237_RS08845
uniprot id: A0A0M4SIQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

199:CCON33237 RS04490
gene id: 199:CCON33237_RS04490
uniprot id: A0A0M4SUE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

199:CCON33237 RS02590
gene id: 199:CCON33237_RS02590
uniprot id: A0A0M4TM53
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

199:CCON33237 RS06500
gene id: 199:CCON33237_RS06500
uniprot id: A0A0M4SC56
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

199:CCON33237 RS08200
gene id: 199:CCON33237_RS08200
uniprot id: A0A0M4SUJ8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

199:CCON33237 RS06995
gene id: 199:CCON33237_RS06995
uniprot id: A0A0M4SCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

199:CCON33237 RS06680
gene id: 199:CCON33237_RS06680
uniprot id: A0A0M5MEQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

199:CCON33237 RS09035
gene id: 199:CCON33237_RS09035
uniprot id: A0A0M4SD29
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

199:CCON33237 RS00140
gene id: 199:CCON33237_RS00140
uniprot id: A0A0M4S9W5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

199:CCON33237 RS07940
gene id: 199:CCON33237_RS07940
uniprot id: A0A0M4SUG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

199:CCON33237 RS08930
gene id: 199:CCON33237_RS08930
uniprot id: A0A0M3V2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

199:CCON33237 RS01185
gene id: 199:CCON33237_RS01185
uniprot id: A0A0M4ST62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

199:CCON33237 RS03200
gene id: 199:CCON33237_RS03200
uniprot id: A0A0M5MEF0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

199:CCON33237 RS08785
gene id: 199:CCON33237_RS08785
uniprot id: A0A0M3V2R2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

199:CCON33237 RS03455
gene id: 199:CCON33237_RS03455
uniprot id: A0A0M4SSS0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

199:CCON33237 RS08870
gene id: 199:CCON33237_RS08870
uniprot id: A0A0M4SUS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

199:CCON33237 RS08700
gene id: 199:CCON33237_RS08700
uniprot id: A0A0M4SCZ1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS05850
gene id: 199:CCON33237_RS05850
uniprot id: A0A0M5MEN2
names: Similarity
messages: Belongs to the NadC/ModD family.

199:CCON33237 RS06225
gene id: 199:CCON33237_RS06225
uniprot id: A0A0M4TMM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS04810
gene id: 199:CCON33237_RS04810
uniprot id: A0A0M3V2B5
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

199:CCON33237 RS05340
gene id: 199:CCON33237_RS05340
uniprot id: A0A0M4SHK9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

199:CCON33237 RS06055
gene id: 199:CCON33237_RS06055
uniprot id: A0A0M4SUV4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

199:CCON33237 RS05495
gene id: 199:CCON33237_RS05495
uniprot id: A0A0M3V2E1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

199:CCON33237 RS06615
gene id: 199:CCON33237_RS06615
uniprot id: A0A0M3V2I2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

199:CCON33237 RS03710
gene id: 199:CCON33237_RS03710
uniprot id: A0A0M3V272
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

199:CCON33237 RS04055
gene id: 199:CCON33237_RS04055
uniprot id: A0A0M4SB97
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

199:CCON33237 RS06505
gene id: 199:CCON33237_RS06505
uniprot id: A0A0M3V2H8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

199:CCON33237 RS06100
gene id: 199:CCON33237_RS06100
uniprot id: A0A0M5MEH8
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS01925
gene id: 199:CCON33237_RS01925
uniprot id: A0A0M4TAC2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

199:CCON33237 RS02525
gene id: 199:CCON33237_RS02525
uniprot id: A0A0M4TM45
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

199:CCON33237 RS06155
gene id: 199:CCON33237_RS06155
uniprot id: A0A0M5MED9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

199:CCON33237 RS03330
gene id: 199:CCON33237_RS03330
uniprot id: A0A0M5TIC4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

199:CCON33237 RS07775
gene id: 199:CCON33237_RS07775
uniprot id: A0A0M5MEM6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

199:CCON33237 RS02305
gene id: 199:CCON33237_RS02305
uniprot id: A0A0M3V223
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

199:CCON33237 RS00205
gene id: 199:CCON33237_RS00205
uniprot id: A0A0M4SL35
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

199:CCON33237 RS04415
gene id: 199:CCON33237_RS04415
uniprot id: A0A0M4TMS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

199:CCON33237 RS02500
gene id: 199:CCON33237_RS02500
uniprot id: A0A0M4SLW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

199:CCON33237 RS03590
gene id: 199:CCON33237_RS03590
uniprot id: A0A0M4SST5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

199:CCON33237 RS06590
gene id: 199:CCON33237_RS06590
uniprot id: A0A0M4SHZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

199:CCON33237 RS07450
gene id: 199:CCON33237_RS07450
uniprot id: A0A0M4TCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

199:CCON33237 RS00040
gene id: 199:CCON33237_RS00040
uniprot id: A0A0M4SST3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

199:CCON33237 RS00930
gene id: 199:CCON33237_RS00930
uniprot id: A0A0M3V209
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

199:CCON33237 RS03210
gene id: 199:CCON33237_RS03210
uniprot id: A0A0M4SGV2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

199:CCON33237 RS02930
gene id: 199:CCON33237_RS02930
uniprot id: A0A0M3V285
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS09145
gene id: 199:CCON33237_RS09145
uniprot id: A0A0M5MEP1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

199:CCON33237 RS08830
gene id: 199:CCON33237_RS08830
uniprot id: A0A0M5MEW7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

199:CCON33237 RS04365
gene id: 199:CCON33237_RS04365
uniprot id: A0A0M3V2D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

199:CCON33237 RS02990
gene id: 199:CCON33237_RS02990
uniprot id: A0A0M4SM22
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

199:CCON33237 RS03305
gene id: 199:CCON33237_RS03305
uniprot id: A0A0M4SSQ4
names: Similarity
messages: Belongs to the SCO1/2 family.

199:CCON33237 RS07580
gene id: 199:CCON33237_RS07580
uniprot id: A0A0M3V2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

199:CCON33237 RS01455
gene id: 199:CCON33237_RS01455
uniprot id: A0A0M4SS53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

199:CCON33237 RS02905
gene id: 199:CCON33237_RS02905
uniprot id: A0A0M5MIJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

199:CCON33237 RS05205
gene id: 199:CCON33237_RS05205
uniprot id: A0A0M4TN19
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

199:CCON33237 RS01505
gene id: 199:CCON33237_RS01505
uniprot id: A0A0M5ME08
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

199:CCON33237 RS03370
gene id: 199:CCON33237_RS03370
uniprot id: A0A0M3V260
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

199:CCON33237 RS03780
gene id: 199:CCON33237_RS03780
uniprot id: A0A0M3V2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

199:CCON33237 RS00515
gene id: 199:CCON33237_RS00515
uniprot id: A0A0M5ME26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

199:CCON33237 RS04700
gene id: 199:CCON33237_RS04700
uniprot id: A0A0M4ST81
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

199:CCON33237 RS00715
gene id: 199:CCON33237_RS00715
uniprot id: A0A0M4T9Y0
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

199:CCON33237 RS07805
gene id: 199:CCON33237_RS07805
uniprot id: A0A0M5MEJ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS08215
gene id: 199:CCON33237_RS08215
uniprot id: A0A0M4SCT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS06325
gene id: 199:CCON33237_RS06325
uniprot id: A0A0M5TIB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

199:CCON33237 RS07525
gene id: 199:CCON33237_RS07525
uniprot id: A0A0M5MES8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

199:CCON33237 RS06700
gene id: 199:CCON33237_RS06700
uniprot id: A0A0M4SND8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

199:CCON33237 RS09135
gene id: 199:CCON33237_RS09135
uniprot id: A0A0M4SVY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

199:CCON33237 RS00605
gene id: 199:CCON33237_RS00605
uniprot id: A0A0M5MEE6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

199:CCON33237 RS06795
gene id: 199:CCON33237_RS06795
uniprot id: A0A0M3V2I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

199:CCON33237 RS02560
gene id: 199:CCON33237_RS02560
uniprot id: A0A0M3V232
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

199:CCON33237 RS01405
gene id: 199:CCON33237_RS01405
uniprot id: A0A0M4SAA5
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

199:CCON33237 RS08370
gene id: 199:CCON33237_RS08370
uniprot id: A0A0M4SVP7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

199:CCON33237 RS03265
gene id: 199:CCON33237_RS03265
uniprot id: A0A0M3V256
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

199:CCON33237 RS06075
gene id: 199:CCON33237_RS06075
uniprot id: A0A0M4STT0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS05115
gene id: 199:CCON33237_RS05115
uniprot id: A0A0M4STH3
names: Similarity
messages: Belongs to the peptidase A31 family.

199:CCON33237 RS08605
gene id: 199:CCON33237_RS08605
uniprot id: A0A0M4SVR9
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS07145
gene id: 199:CCON33237_RS07145
uniprot id: A0A0M3V2P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS06885
gene id: 199:CCON33237_RS06885
uniprot id: A0A0M4TNJ1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

199:CCON33237 RS08955
gene id: 199:CCON33237_RS08955
uniprot id: A0A0M5TIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

199:CCON33237 RS07905
gene id: 199:CCON33237_RS07905
uniprot id: A0A0M5MKQ3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

199:CCON33237 RS02830
gene id: 199:CCON33237_RS02830
uniprot id: A0A0M3V281
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

199:CCON33237 RS07535
gene id: 199:CCON33237_RS07535
uniprot id: A0A0M4TNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

199:CCON33237 RS07545
gene id: 199:CCON33237_RS07545
uniprot id: A0A0M4SVC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

199:CCON33237 RS06860
gene id: 199:CCON33237_RS06860
uniprot id: A0A0M4TC49
names: Similarity
messages: Belongs to the UDPGP type 2 family.

199:CCON33237 RS02325
gene id: 199:CCON33237_RS02325
uniprot id: A0A0M3V263
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS07930
gene id: 199:CCON33237_RS07930
uniprot id: A0A0M3V2N3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

199:CCON33237 RS02820
gene id: 199:CCON33237_RS02820
uniprot id: A0A0M5ME87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

199:CCON33237 RS08475
gene id: 199:CCON33237_RS08475
uniprot id: A0A0M4TCQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

199:CCON33237 RS08005
gene id: 199:CCON33237_RS08005
uniprot id: A0A0M4SUH4
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS09050
gene id: 199:CCON33237_RS09050
uniprot id: A0A0M5MGE7
names: Similarity
messages: Belongs to the RecJ family.

199:CCON33237 RS01565
gene id: 199:CCON33237_RS01565
uniprot id: A0A0M5MIF4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

199:CCON33237 RS02650
gene id: 199:CCON33237_RS02650
uniprot id: A0A0M4TM62
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

199:CCON33237 RS07280
gene id: 199:CCON33237_RS07280
uniprot id: A0A0M4SI66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

199:CCON33237 RS09700
gene id: 199:CCON33237_RS09700
uniprot id: A0A0M4SP90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

199:CCON33237 RS07000
gene id: 199:CCON33237_RS07000
uniprot id: A0A0M4TC65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS02215
gene id: 199:CCON33237_RS02215
uniprot id: A0A0M4STJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

199:CCON33237 RS06915
gene id: 199:CCON33237_RS06915
uniprot id: A0A0M4TMV5
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

199:CCON33237 RS05995
gene id: 199:CCON33237_RS05995
uniprot id: A0A0M4SUU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

199:CCON33237 RS07840
gene id: 199:CCON33237_RS07840
uniprot id: A0A0M5MET8
names: Similarity
messages: Belongs to the GSP E family.

199:CCON33237 RS03960
gene id: 199:CCON33237_RS03960
uniprot id: A0A0M5MEU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

199:CCON33237 RS03500
gene id: 199:CCON33237_RS03500
uniprot id: A0A0M3V264
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

199:CCON33237 RS04940
gene id: 199:CCON33237_RS04940
uniprot id: A0A0M3V2G0
names: Similarity
messages: Belongs to the peptidase S41A family.

199:CCON33237 RS03480
gene id: 199:CCON33237_RS03480
uniprot id: A0A0M4TAX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

199:CCON33237 RS08540
gene id: 199:CCON33237_RS08540
uniprot id: A0A0M4TND8
names: Similarity
messages: Belongs to the class-I fumarase family.

199:CCON33237 RS03070
gene id: 199:CCON33237_RS03070
uniprot id: A0A0M5MFX9
names: Similarity
messages: Belongs to the type III secretion exporter family.

199:CCON33237 RS00905
gene id: 199:CCON33237_RS00905
uniprot id: A0A0M4SA50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

199:CCON33237 RS07370
gene id: 199:CCON33237_RS07370
uniprot id: A0A0M3V2L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

199:CCON33237 RS07695
gene id: 199:CCON33237_RS07695
uniprot id: A0A0M4SNQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

199:CCON33237 RS02610
gene id: 199:CCON33237_RS02610
uniprot id: A0A0M3V234
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

199:CCON33237 RS05120
gene id: 199:CCON33237_RS05120
uniprot id: A0A0M4SMU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

199:CCON33237 RS01140
gene id: 199:CCON33237_RS01140
uniprot id: A0A0M4SS17
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

199:CCON33237 RS08135
gene id: 199:CCON33237_RS08135
uniprot id: A0A0M3V2P0
names: Subcellular Location Annotation
messages: Membrane

199:CCON33237 RS05100
gene id: 199:CCON33237_RS05100
uniprot id: A0A0M5MEQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

199:CCON33237 RS06930
gene id: 199:CCON33237_RS06930
uniprot id: A0A0M3V2N4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

199:CCON33237 RS08480
gene id: 199:CCON33237_RS08480
uniprot id: A0A0M5MEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

199:CCON33237 RS01825
gene id: 199:CCON33237_RS01825
uniprot id: A0A0M4STE5
names: Similarity
messages: Belongs to the UPF0423 family.

199:CCON33237 RS02210
gene id: 199:CCON33237_RS02210
uniprot id: A0A0M4SGJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS00565
gene id: 199:CCON33237_RS00565
uniprot id: A0A0M4SA11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

199:CCON33237 RS08795
gene id: 199:CCON33237_RS08795
uniprot id: A0A0M5MEN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

199:CCON33237 RS04275
gene id: 199:CCON33237_RS04275
uniprot id: A0A0M4TB72
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

199:CCON33237 RS00795
gene id: 199:CCON33237_RS00795
uniprot id: A0A0M4TLK9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

199:CCON33237 RS03510
gene id: 199:CCON33237_RS03510
uniprot id: A0A0M5ME70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

199:CCON33237 RS05160
gene id: 199:CCON33237_RS05160
uniprot id: A0A0M3V2G8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

199:CCON33237 RS04580
gene id: 199:CCON33237_RS04580
uniprot id: A0A0M4SMM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

199:CCON33237 RS08820
gene id: 199:CCON33237_RS08820
uniprot id: A0A0M4SD07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

199:CCON33237 RS03605
gene id: 199:CCON33237_RS03605
uniprot id: A0A0M3V268
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

199:CCON33237 RS00115
gene id: 199:CCON33237_RS00115
uniprot id: A0A0M5MDX5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

199:CCON33237 RS08780
gene id: 199:CCON33237_RS08780
uniprot id: A0A0M4SIP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

199:CCON33237 RS08140
gene id: 199:CCON33237_RS08140
uniprot id: A0A0M4SNX4
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

199:CCON33237 RS06425
gene id: 199:CCON33237_RS06425
uniprot id: A0A0M3V2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

199:CCON33237 RS01230
gene id: 199:CCON33237_RS01230
uniprot id: A0A0M5ME47
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

199:CCON33237 RS01920
gene id: 199:CCON33237_RS01920
uniprot id: A0A0M4SAH2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

199:CCON33237 RS06180
gene id: 199:CCON33237_RS06180
uniprot id: A0A0M4SC14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.