198467:AFK25 RS09285
gene id: 198467:AFK25_RS09285
uniprot id: A0A0A2SG42
names: Similarity
messages: Belongs to the threonine aldolase family.

198467:AFK25 RS05680
gene id: 198467:AFK25_RS05680
uniprot id: A0A0A2SMI4
names: Similarity
messages: Belongs to the FlgD family.

198467:AFK25 RS04855
gene id: 198467:AFK25_RS04855
uniprot id: M5QQ37
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

198467:AFK25 RS09635
gene id: 198467:AFK25_RS09635
uniprot id: A0A0A2SFY9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

198467:AFK25 RS10965
gene id: 198467:AFK25_RS10965
uniprot id: M5QV10
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

198467:AFK25 RS10725
gene id: 198467:AFK25_RS10725
uniprot id: A0A0A2SKH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS09810
gene id: 198467:AFK25_RS09810
uniprot id: M5QRE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

198467:AFK25 RS05585
gene id: 198467:AFK25_RS05585
uniprot id: M5QX97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

198467:AFK25 RS14045
gene id: 198467:AFK25_RS14045
uniprot id: M5QVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS01275
gene id: 198467:AFK25_RS01275
uniprot id: A0A0A2SLW2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

198467:AFK25 RS05150
gene id: 198467:AFK25_RS05150
uniprot id: A0A0A2T0S0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

198467:AFK25 RS00375
gene id: 198467:AFK25_RS00375
uniprot id: M5QWK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

198467:AFK25 RS14210
gene id: 198467:AFK25_RS14210
uniprot id: A0A0A2T2R4
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS14900
gene id: 198467:AFK25_RS14900
uniprot id: M5R7W1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS13200
gene id: 198467:AFK25_RS13200
uniprot id: A0A0A2SZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

198467:AFK25 RS04065
gene id: 198467:AFK25_RS04065
uniprot id: A0A0A2SJV2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

198467:AFK25 RS11100
gene id: 198467:AFK25_RS11100
uniprot id: A0A0A2SNB9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

198467:AFK25 RS10055
gene id: 198467:AFK25_RS10055
uniprot id: M5R7C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS01085
gene id: 198467:AFK25_RS01085
uniprot id: M5QS62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

198467:AFK25 RS08125
gene id: 198467:AFK25_RS08125
uniprot id: A0A0A2SXA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

198467:AFK25 RS06145
gene id: 198467:AFK25_RS06145
uniprot id: A0A0A2SI11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

198467:AFK25 RS06335
gene id: 198467:AFK25_RS06335
uniprot id: A0A0A2T037
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

198467:AFK25 RS12160
gene id: 198467:AFK25_RS12160
uniprot id: M5R6C4
names: Similarity
messages: Belongs to the Dps family.

198467:AFK25 RS13930
gene id: 198467:AFK25_RS13930
uniprot id: M5R7Q8
names: Similarity
messages: Belongs to the FBPase class 2 family.

198467:AFK25 RS03190
gene id: 198467:AFK25_RS03190
uniprot id: A0A0A2SQ17
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

198467:AFK25 RS10240
gene id: 198467:AFK25_RS10240
uniprot id: A0A0A2SJU1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

198467:AFK25 RS06990
gene id: 198467:AFK25_RS06990
uniprot id: A0A0A2SZE8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

198467:AFK25 RS14630
gene id: 198467:AFK25_RS14630
uniprot id: M5RBV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

198467:AFK25 RS09410
gene id: 198467:AFK25_RS09410
uniprot id: M5R718
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

198467:AFK25 RS13785
gene id: 198467:AFK25_RS13785
uniprot id: M5R925
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

198467:AFK25 RS00535
gene id: 198467:AFK25_RS00535
uniprot id: A0A0A2SLW4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

198467:AFK25 RS12635
gene id: 198467:AFK25_RS12635
uniprot id: M5QTG7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

198467:AFK25 RS10780
gene id: 198467:AFK25_RS10780
uniprot id: A0A0A2SFE4
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS12145
gene id: 198467:AFK25_RS12145
uniprot id: A0A0A2SQR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS11800
gene id: 198467:AFK25_RS11800
uniprot id: M5R9T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

198467:AFK25 RS08565
gene id: 198467:AFK25_RS08565
uniprot id: A0A0A2SGH5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

198467:AFK25 RS14620
gene id: 198467:AFK25_RS14620
uniprot id: A0A0A2SKC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS08145
gene id: 198467:AFK25_RS08145
uniprot id: A0A0A2SGC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

198467:AFK25 RS00260
gene id: 198467:AFK25_RS00260
uniprot id: M5QXX8
names: Similarity
messages: Belongs to the RutC family.

198467:AFK25 RS11055
gene id: 198467:AFK25_RS11055
uniprot id: A0A0A2SJ80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

198467:AFK25 RS12930
gene id: 198467:AFK25_RS12930
uniprot id: M5QRC0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

198467:AFK25 RS11330
gene id: 198467:AFK25_RS11330
uniprot id: M5QT10
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS05330
gene id: 198467:AFK25_RS05330
uniprot id: A0A0A2T0P1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

198467:AFK25 RS00605
gene id: 198467:AFK25_RS00605
uniprot id: M5QUI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

198467:AFK25 RS08755
gene id: 198467:AFK25_RS08755
uniprot id: A0A0A2SYK5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

198467:AFK25 RS03900
gene id: 198467:AFK25_RS03900
uniprot id: A0A0A2SQA2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

198467:AFK25 RS01255
gene id: 198467:AFK25_RS01255
uniprot id: A0A0A2SIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS01050
gene id: 198467:AFK25_RS01050
uniprot id: A0A0A2SIM8
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

198467:AFK25 RS03125
gene id: 198467:AFK25_RS03125
uniprot id: A0A0A2SP61
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

198467:AFK25 RS05255
gene id: 198467:AFK25_RS05255
uniprot id: M5RCT9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

198467:AFK25 RS09890
gene id: 198467:AFK25_RS09890
uniprot id: M5QSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

198467:AFK25 RS05945
gene id: 198467:AFK25_RS05945
uniprot id: A0A0A2SN78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

198467:AFK25 RS09750
gene id: 198467:AFK25_RS09750
uniprot id: M5R3G7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

198467:AFK25 RS11185
gene id: 198467:AFK25_RS11185
uniprot id: M5R9I4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

198467:AFK25 RS05275
gene id: 198467:AFK25_RS05275
uniprot id: M5QWL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

198467:AFK25 RS03370
gene id: 198467:AFK25_RS03370
uniprot id: A0A0A2T2A1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

198467:AFK25 RS07100
gene id: 198467:AFK25_RS07100
uniprot id: A0A0A2SLC7
names: Similarity
messages: Belongs to the peptidase A31 family.

198467:AFK25 RS03990
gene id: 198467:AFK25_RS03990
uniprot id: A0A0A2SJC3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

198467:AFK25 RS09045
gene id: 198467:AFK25_RS09045
uniprot id: M5QQA6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

198467:AFK25 RS11575
gene id: 198467:AFK25_RS11575
uniprot id: M5QV87
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS05410
gene id: 198467:AFK25_RS05410
uniprot id: A0A0A2SJQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

198467:AFK25 RS13060
gene id: 198467:AFK25_RS13060
uniprot id: M5R807
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RacA family.
messages: Cytoplasm
messages: Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure.

198467:AFK25 RS01780
gene id: 198467:AFK25_RS01780
uniprot id: M5RC89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

198467:AFK25 RS08895
gene id: 198467:AFK25_RS08895
uniprot id: A0A0A2SGB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

198467:AFK25 RS04070
gene id: 198467:AFK25_RS04070
uniprot id: A0A0A2SX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

198467:AFK25 RS11495
gene id: 198467:AFK25_RS11495
uniprot id: M5QTT5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

198467:AFK25 RS07695
gene id: 198467:AFK25_RS07695
uniprot id: A0A0A2SI63
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

198467:AFK25 RS05480
gene id: 198467:AFK25_RS05480
uniprot id: M5RD01
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

198467:AFK25 RS06845
gene id: 198467:AFK25_RS06845
uniprot id: A0A0A2SLH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

198467:AFK25 RS04365
gene id: 198467:AFK25_RS04365
uniprot id: A0A0A2SLC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

198467:AFK25 RS00615
gene id: 198467:AFK25_RS00615
uniprot id: M5R6L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

198467:AFK25 RS14030
gene id: 198467:AFK25_RS14030
uniprot id: M5R7S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

198467:AFK25 RS11505
gene id: 198467:AFK25_RS11505
uniprot id: M5R5V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS00205
gene id: 198467:AFK25_RS00205
uniprot id: A0A0A2SIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

198467:AFK25 RS12260
gene id: 198467:AFK25_RS12260
uniprot id: M5QUC2
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

198467:AFK25 RS06780
gene id: 198467:AFK25_RS06780
uniprot id: M5QP13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

198467:AFK25 RS07630
gene id: 198467:AFK25_RS07630
uniprot id: A0A0A2SH12
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

198467:AFK25 RS01585
gene id: 198467:AFK25_RS01585
uniprot id: A0A0A2SLG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS13225
gene id: 198467:AFK25_RS13225
uniprot id: A0A0A2SZM7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

198467:AFK25 RS05180
gene id: 198467:AFK25_RS05180
uniprot id: A0A0A2SJT5
names: Similarity
messages: Belongs to the transpeptidase family.

198467:AFK25 RS06750
gene id: 198467:AFK25_RS06750
uniprot id: M5R5K5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS08240
gene id: 198467:AFK25_RS08240
uniprot id: A0A0A2SJI4
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

198467:AFK25 RS03350
gene id: 198467:AFK25_RS03350
uniprot id: A0A0A2SQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

198467:AFK25 RS12910
gene id: 198467:AFK25_RS12910
uniprot id: A0A0A2SHN5
names: Similarity
messages: Belongs to the sigma-54 factor family.

198467:AFK25 RS03725
gene id: 198467:AFK25_RS03725
uniprot id: A0A0A2SQ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

198467:AFK25 RS10445
gene id: 198467:AFK25_RS10445
uniprot id: M5QT97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

198467:AFK25 RS09950
gene id: 198467:AFK25_RS09950
uniprot id: A0A0A2SXY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

198467:AFK25 RS02630
gene id: 198467:AFK25_RS02630
uniprot id: A0A0A2SL09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

198467:AFK25 RS05470
gene id: 198467:AFK25_RS05470
uniprot id: M5R950
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

198467:AFK25 RS01405
gene id: 198467:AFK25_RS01405
uniprot id: M5RCJ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

198467:AFK25 RS09120
gene id: 198467:AFK25_RS09120
uniprot id: A0A0A2SHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

198467:AFK25 RS04585
gene id: 198467:AFK25_RS04585
uniprot id: A0A0A2SQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

198467:AFK25 RS04805
gene id: 198467:AFK25_RS04805
uniprot id: A0A0A2SM71
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

198467:AFK25 RS12730
gene id: 198467:AFK25_RS12730
uniprot id: A0A0A2SHR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

198467:AFK25 RS11090
gene id: 198467:AFK25_RS11090
uniprot id: A0A0A2T1C2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

198467:AFK25 RS08370
gene id: 198467:AFK25_RS08370
uniprot id: A0A0A2SJL4
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

198467:AFK25 RS01240
gene id: 198467:AFK25_RS01240
uniprot id: M5QRJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

198467:AFK25 RS12690
gene id: 198467:AFK25_RS12690
uniprot id: A0A0A2SZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS02690
gene id: 198467:AFK25_RS02690
uniprot id: A0A0A2SPW1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

198467:AFK25 RS01025
gene id: 198467:AFK25_RS01025
uniprot id: A0A0A2SFN3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

198467:AFK25 RS09000
gene id: 198467:AFK25_RS09000
uniprot id: A0A0A2SG94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

198467:AFK25 RS14345
gene id: 198467:AFK25_RS14345
uniprot id: A0A7U4NRZ7
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS07415
gene id: 198467:AFK25_RS07415
uniprot id: A0A0A2SM54
names: Similarity
messages: Belongs to the EamA transporter family.

198467:AFK25 RS07555
gene id: 198467:AFK25_RS07555
uniprot id: A0A0A2SM40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

198467:AFK25 RS10285
gene id: 198467:AFK25_RS10285
uniprot id: A0A0A2SGV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS00475
gene id: 198467:AFK25_RS00475
uniprot id: M5QUG7
names: Similarity
messages: Belongs to the ycf81 family.

198467:AFK25 RS09395
gene id: 198467:AFK25_RS09395
uniprot id: A0A0A2SG26
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

198467:AFK25 RS00195
gene id: 198467:AFK25_RS00195
uniprot id: M5RCI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

198467:AFK25 RS01820
gene id: 198467:AFK25_RS01820
uniprot id: A0A0A2SQL4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

198467:AFK25 RS08360
gene id: 198467:AFK25_RS08360
uniprot id: A0A0A2SEK8
names: Similarity
messages: Belongs to the asparagine synthetase family.

198467:AFK25 RS00025
gene id: 198467:AFK25_RS00025
uniprot id: A0A0A2SXF0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

198467:AFK25 RS12610
gene id: 198467:AFK25_RS12610
uniprot id: M5QTG1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

198467:AFK25 RS13960
gene id: 198467:AFK25_RS13960
uniprot id: A0A0A2SLZ4
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

198467:AFK25 RS00720
gene id: 198467:AFK25_RS00720
uniprot id: M5QTU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

198467:AFK25 RS12240
gene id: 198467:AFK25_RS12240
uniprot id: A0A0A2SRK3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

198467:AFK25 RS10505
gene id: 198467:AFK25_RS10505
uniprot id: A0A0A2SGS9
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS11110
gene id: 198467:AFK25_RS11110
uniprot id: M5QTM8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

198467:AFK25 RS13535
gene id: 198467:AFK25_RS13535
uniprot id: M5R591
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

198467:AFK25 RS01730
gene id: 198467:AFK25_RS01730
uniprot id: A0A0A2SMM0
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

198467:AFK25 RS06435
gene id: 198467:AFK25_RS06435
uniprot id: A0A0A2T0T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

198467:AFK25 RS11980
gene id: 198467:AFK25_RS11980
uniprot id: A0A0A2T0W8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

198467:AFK25 RS10995
gene id: 198467:AFK25_RS10995
uniprot id: A0A0A2SKH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS14565
gene id: 198467:AFK25_RS14565
uniprot id: M5QXB1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

198467:AFK25 RS04220
gene id: 198467:AFK25_RS04220
uniprot id: A0A0A2SLE0
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS12625
gene id: 198467:AFK25_RS12625
uniprot id: A0A0A2SMU3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

198467:AFK25 RS07950
gene id: 198467:AFK25_RS07950
uniprot id: M5QUG1
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS12950
gene id: 198467:AFK25_RS12950
uniprot id: M5R466
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

198467:AFK25 RS09130
gene id: 198467:AFK25_RS09130
uniprot id: M5QR18
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

198467:AFK25 RS02720
gene id: 198467:AFK25_RS02720
uniprot id: A0A0A2SJW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS02715
gene id: 198467:AFK25_RS02715
uniprot id: M5QUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

198467:AFK25 RS08375
gene id: 198467:AFK25_RS08375
uniprot id: A0A0A2SFT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

198467:AFK25 RS04255
gene id: 198467:AFK25_RS04255
uniprot id: A0A0A2SRB0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

198467:AFK25 RS09940
gene id: 198467:AFK25_RS09940
uniprot id: M5QT08
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the octanoyltransferase LipM family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. The reaction proceeds via an octanoyl-thioester enzyme intermediate.
messages: Monomer.

198467:AFK25 RS09430
gene id: 198467:AFK25_RS09430
uniprot id: M5QQI1
names: Similarity
messages: Belongs to the Fur family.

198467:AFK25 RS01065
gene id: 198467:AFK25_RS01065
uniprot id: A0A0A2SJH0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

198467:AFK25 RS06865
gene id: 198467:AFK25_RS06865
uniprot id: A0A0A2SIJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

198467:AFK25 RS01425
gene id: 198467:AFK25_RS01425
uniprot id: A0A0A2SQW0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

198467:AFK25 RS13765
gene id: 198467:AFK25_RS13765
uniprot id: M5QT95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

198467:AFK25 RS10495
gene id: 198467:AFK25_RS10495
uniprot id: A0A0A2SKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

198467:AFK25 RS06705
gene id: 198467:AFK25_RS06705
uniprot id: A0A0A2SPH0
names: Similarity
messages: Belongs to the CinA family.

198467:AFK25 RS05550
gene id: 198467:AFK25_RS05550
uniprot id: A0A0A2SIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

198467:AFK25 RS13045
gene id: 198467:AFK25_RS13045
uniprot id: A0A0A2SMJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

198467:AFK25 RS10705
gene id: 198467:AFK25_RS10705
uniprot id: M5QTE7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

198467:AFK25 RS14260
gene id: 198467:AFK25_RS14260
uniprot id: A0A0A2T2Q1
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

198467:AFK25 RS07230
gene id: 198467:AFK25_RS07230
uniprot id: M5R6W1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS14335
gene id: 198467:AFK25_RS14335
uniprot id: A0A7U4NRZ8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

198467:AFK25 RS08400
gene id: 198467:AFK25_RS08400
uniprot id: A0A0A2SFT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

198467:AFK25 RS09525
gene id: 198467:AFK25_RS09525
uniprot id: A0A0A2SK67
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

198467:AFK25 RS02960
gene id: 198467:AFK25_RS02960
uniprot id: A0A0A2SK03
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS14640
gene id: 198467:AFK25_RS14640
uniprot id: A0A0A2SXE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

198467:AFK25 RS09710
gene id: 198467:AFK25_RS09710
uniprot id: A0A0A2SK33
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

198467:AFK25 RS02195
gene id: 198467:AFK25_RS02195
uniprot id: A0A0A2SNN6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

198467:AFK25 RS08555
gene id: 198467:AFK25_RS08555
uniprot id: A0A7U4NPW2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

198467:AFK25 RS02385
gene id: 198467:AFK25_RS02385
uniprot id: A0A0A2SKW0
names: Similarity
messages: Belongs to the peptidase S14 family.

198467:AFK25 RS12830
gene id: 198467:AFK25_RS12830
uniprot id: A0A0A2SLU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

198467:AFK25 RS00270
gene id: 198467:AFK25_RS00270
uniprot id: M5RCG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS01920
gene id: 198467:AFK25_RS01920
uniprot id: M5R8F4
names: Similarity
messages: Belongs to the UPF0374 family.

198467:AFK25 RS04980
gene id: 198467:AFK25_RS04980
uniprot id: A0A0A2SWA8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

198467:AFK25 RS06495
gene id: 198467:AFK25_RS06495
uniprot id: A0A0A2SEB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS07210
gene id: 198467:AFK25_RS07210
uniprot id: A0A0A2SM79
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS01300
gene id: 198467:AFK25_RS01300
uniprot id: M5QY31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

198467:AFK25 RS11240
gene id: 198467:AFK25_RS11240
uniprot id: A0A0A2SKD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

198467:AFK25 RS04330
gene id: 198467:AFK25_RS04330
uniprot id: A0A0A2SQE6
names: Function
names: Similarity
messages: Belongs to the LutC/YkgG family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.

198467:AFK25 RS06345
gene id: 198467:AFK25_RS06345
uniprot id: A0A0A2SM23
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
messages: Belongs to the radical SAM superfamily. NifB family.

198467:AFK25 RS13290
gene id: 198467:AFK25_RS13290
uniprot id: A0A0A2SLL2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

198467:AFK25 RS00580
gene id: 198467:AFK25_RS00580
uniprot id: M5QUI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

198467:AFK25 RS12185
gene id: 198467:AFK25_RS12185
uniprot id: A0A0A2SMV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS06560
gene id: 198467:AFK25_RS06560
uniprot id: A0A0A2SJE5
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

198467:AFK25 RS05870
gene id: 198467:AFK25_RS05870
uniprot id: M5QX72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

198467:AFK25 RS03285
gene id: 198467:AFK25_RS03285
uniprot id: A0A0A2SLA1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

198467:AFK25 RS03940
gene id: 198467:AFK25_RS03940
uniprot id: A0A0A2SJC8
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

198467:AFK25 RS13065
gene id: 198467:AFK25_RS13065
uniprot id: A0A0A2SHK8
names: Similarity
messages: Belongs to the peptidase S41A family.

198467:AFK25 RS10525
gene id: 198467:AFK25_RS10525
uniprot id: M5QUU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

198467:AFK25 RS14515
gene id: 198467:AFK25_RS14515
uniprot id: M5QVM3
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS08680
gene id: 198467:AFK25_RS08680
uniprot id: M5R2W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

198467:AFK25 RS00775
gene id: 198467:AFK25_RS00775
uniprot id: M5RAE9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

198467:AFK25 RS10180
gene id: 198467:AFK25_RS10180
uniprot id: A0A0A2SXV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

198467:AFK25 RS06370
gene id: 198467:AFK25_RS06370
uniprot id: A0A0A2SM16
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

198467:AFK25 RS14065
gene id: 198467:AFK25_RS14065
uniprot id: M5RBM5
names: Similarity
messages: Belongs to the UPF0741 family.

198467:AFK25 RS13015
gene id: 198467:AFK25_RS13015
uniprot id: A0A0A2SHL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

198467:AFK25 RS11270
gene id: 198467:AFK25_RS11270
uniprot id: A0A0A2SN91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS14150
gene id: 198467:AFK25_RS14150
uniprot id: A0A0A2SQJ3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

198467:AFK25 RS13840
gene id: 198467:AFK25_RS13840
uniprot id: M5QVM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

198467:AFK25 RS04390
gene id: 198467:AFK25_RS04390
uniprot id: A0A0A2SLB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Homotetramer.

198467:AFK25 RS04910
gene id: 198467:AFK25_RS04910
uniprot id: A0A0A2SI97
names: Similarity
messages: Belongs to the UPF0223 family.

198467:AFK25 RS07525
gene id: 198467:AFK25_RS07525
uniprot id: A0A0A2SH29
names: Function
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.

198467:AFK25 RS03010
gene id: 198467:AFK25_RS03010
uniprot id: A0A0A2SPZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS08590
gene id: 198467:AFK25_RS08590
uniprot id: M5QSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

198467:AFK25 RS08465
gene id: 198467:AFK25_RS08465
uniprot id: M5QTC3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS07235
gene id: 198467:AFK25_RS07235
uniprot id: M5QU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

198467:AFK25 RS08630
gene id: 198467:AFK25_RS08630
uniprot id: A0A0A2SYN1
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS04820
gene id: 198467:AFK25_RS04820
uniprot id: A0A0A2SQZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

198467:AFK25 RS00175
gene id: 198467:AFK25_RS00175
uniprot id: A0A0A2SFG2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

198467:AFK25 RS10145
gene id: 198467:AFK25_RS10145
uniprot id: A0A0A2SKS6
names: Caution
names: Similarity
messages: Belongs to the transpeptidase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS05165
gene id: 198467:AFK25_RS05165
uniprot id: A0A0A2SIM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

198467:AFK25 RS05225
gene id: 198467:AFK25_RS05225
uniprot id: A0A0A2SNK9
names: Similarity
messages: Belongs to the UPF0749 family.

198467:AFK25 RS04230
gene id: 198467:AFK25_RS04230
uniprot id: M5QRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

198467:AFK25 RS13750
gene id: 198467:AFK25_RS13750
uniprot id: A0A0A2SM32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

198467:AFK25 RS06655
gene id: 198467:AFK25_RS06655
uniprot id: A0A0A2SPF7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

198467:AFK25 RS02925
gene id: 198467:AFK25_RS02925
uniprot id: A0A0A2T233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

198467:AFK25 RS05645
gene id: 198467:AFK25_RS05645
uniprot id: A0A0A2T0K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

198467:AFK25 RS03270
gene id: 198467:AFK25_RS03270
uniprot id: A0A0A2SQ27
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

198467:AFK25 RS05290
gene id: 198467:AFK25_RS05290
uniprot id: A0A0A2SMP0
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS02790
gene id: 198467:AFK25_RS02790
uniprot id: A0A0A2SL31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS06905
gene id: 198467:AFK25_RS06905
uniprot id: M5QTX0
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspO family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

198467:AFK25 RS11595
gene id: 198467:AFK25_RS11595
uniprot id: M5QTV6
names: Similarity
messages: Belongs to the citrate synthase family.

198467:AFK25 RS00395
gene id: 198467:AFK25_RS00395
uniprot id: A0A0A2SJB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

198467:AFK25 RS10280
gene id: 198467:AFK25_RS10280
uniprot id: M5QQX0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

198467:AFK25 RS01330
gene id: 198467:AFK25_RS01330
uniprot id: A0A0A2SRN8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

198467:AFK25 RS12715
gene id: 198467:AFK25_RS12715
uniprot id: A0A0A2SZW6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

198467:AFK25 RS05395
gene id: 198467:AFK25_RS05395
uniprot id: A0A0A2SIH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

198467:AFK25 RS14530
gene id: 198467:AFK25_RS14530
uniprot id: A0A0A2SGE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

198467:AFK25 RS10490
gene id: 198467:AFK25_RS10490
uniprot id: M5QRR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

198467:AFK25 RS09820
gene id: 198467:AFK25_RS09820
uniprot id: M5R3I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

198467:AFK25 RS04240
gene id: 198467:AFK25_RS04240
uniprot id: A0A0A2SMG8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

198467:AFK25 RS11465
gene id: 198467:AFK25_RS11465
uniprot id: A0A0A2SJ08
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

198467:AFK25 RS01580
gene id: 198467:AFK25_RS01580
uniprot id: A0A0A2SRD0
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS04975
gene id: 198467:AFK25_RS04975
uniprot id: A0A0A2SFC2
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS10200
gene id: 198467:AFK25_RS10200
uniprot id: M5R3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS05350
gene id: 198467:AFK25_RS05350
uniprot id: M5QWY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

198467:AFK25 RS05570
gene id: 198467:AFK25_RS05570
uniprot id: A0A0A2SMT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

198467:AFK25 RS00105
gene id: 198467:AFK25_RS00105
uniprot id: M5RCM4
names: Similarity
messages: Belongs to the DCK/DGK family.

198467:AFK25 RS05910
gene id: 198467:AFK25_RS05910
uniprot id: A0A0A2SMB3
names: Similarity
messages: Belongs to the peptidase M16 family.

198467:AFK25 RS04505
gene id: 198467:AFK25_RS04505
uniprot id: A0A0A2SR73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS12895
gene id: 198467:AFK25_RS12895
uniprot id: M5R458
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

198467:AFK25 RS13985
gene id: 198467:AFK25_RS13985
uniprot id: A0A0A2SLY9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

198467:AFK25 RS00125
gene id: 198467:AFK25_RS00125
uniprot id: M5QWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

198467:AFK25 RS03740
gene id: 198467:AFK25_RS03740
uniprot id: A0A0A2SLI7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

198467:AFK25 RS04590
gene id: 198467:AFK25_RS04590
uniprot id: M5QUU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS02865
gene id: 198467:AFK25_RS02865
uniprot id: M5QSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

198467:AFK25 RS14510
gene id: 198467:AFK25_RS14510
uniprot id: M5R7Z4
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS02595
gene id: 198467:AFK25_RS02595
uniprot id: A0A0A2SNZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some proteins.

198467:AFK25 RS06840
gene id: 198467:AFK25_RS06840
uniprot id: M5QR97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

198467:AFK25 RS07095
gene id: 198467:AFK25_RS07095
uniprot id: M5QUS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

198467:AFK25 RS11125
gene id: 198467:AFK25_RS11125
uniprot id: M5QSW5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

198467:AFK25 RS09500
gene id: 198467:AFK25_RS09500
uniprot id: A0A0A2SG09
names: Similarity
messages: Belongs to the MoaD family.

198467:AFK25 RS08585
gene id: 198467:AFK25_RS08585
uniprot id: A0A0A2SKN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

198467:AFK25 RS09775
gene id: 198467:AFK25_RS09775
uniprot id: M5QQN5
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

198467:AFK25 RS08615
gene id: 198467:AFK25_RS08615
uniprot id: A0A0A2SKM6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

198467:AFK25 RS11855
gene id: 198467:AFK25_RS11855
uniprot id: A0A0A2T1H5
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

198467:AFK25 RS07180
gene id: 198467:AFK25_RS07180
uniprot id: A0A0A2SH79
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS13040
gene id: 198467:AFK25_RS13040
uniprot id: A0A0A2SHL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

198467:AFK25 RS05595
gene id: 198467:AFK25_RS05595
uniprot id: A0A0A2T0L0
names: Similarity
messages: Belongs to the DprA/Smf family.

198467:AFK25 RS11115
gene id: 198467:AFK25_RS11115
uniprot id: M5QV33
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

198467:AFK25 RS11625
gene id: 198467:AFK25_RS11625
uniprot id: M5QT55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

198467:AFK25 RS00235
gene id: 198467:AFK25_RS00235
uniprot id: A0A0A2SE87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

198467:AFK25 RS08855
gene id: 198467:AFK25_RS08855
uniprot id: A0A0A2SYI4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

198467:AFK25 RS05850
gene id: 198467:AFK25_RS05850
uniprot id: A0A0A2T0D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

198467:AFK25 RS10760
gene id: 198467:AFK25_RS10760
uniprot id: A0A0A2SJK1
names: Similarity
messages: Belongs to the RecJ family.

198467:AFK25 RS10350
gene id: 198467:AFK25_RS10350
uniprot id: M5R3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

198467:AFK25 RS09515
gene id: 198467:AFK25_RS09515
uniprot id: A0A0A2SY63
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

198467:AFK25 RS04660
gene id: 198467:AFK25_RS04660
uniprot id: A0A0A2T384
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

198467:AFK25 RS00030
gene id: 198467:AFK25_RS00030
uniprot id: A0A0A2SKD6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

198467:AFK25 RS11315
gene id: 198467:AFK25_RS11315
uniprot id: M5QTS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

198467:AFK25 RS00675
gene id: 198467:AFK25_RS00675
uniprot id: M5RAC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

198467:AFK25 RS00650
gene id: 198467:AFK25_RS00650
uniprot id: M5RAC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

198467:AFK25 RS04440
gene id: 198467:AFK25_RS04440
uniprot id: A0A0A2SQD3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

198467:AFK25 RS06020
gene id: 198467:AFK25_RS06020
uniprot id: A0A0A2SI26
names: Similarity
messages: Belongs to the universal stress protein A family.

198467:AFK25 RS14795
gene id: 198467:AFK25_RS14795
uniprot id: M5QU62
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS12920
gene id: 198467:AFK25_RS12920
uniprot id: M5QTL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

198467:AFK25 RS12785
gene id: 198467:AFK25_RS12785
uniprot id: M5R443
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

198467:AFK25 RS03170
gene id: 198467:AFK25_RS03170
uniprot id: A0A0A2SK38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

198467:AFK25 RS12970
gene id: 198467:AFK25_RS12970
uniprot id: A0A0A2SML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

198467:AFK25 RS04580
gene id: 198467:AFK25_RS04580
uniprot id: M5QVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

198467:AFK25 RS11475
gene id: 198467:AFK25_RS11475
uniprot id: A0A0A2T151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS09540
gene id: 198467:AFK25_RS09540
uniprot id: A0A0A2SY57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

198467:AFK25 RS14295
gene id: 198467:AFK25_RS14295
uniprot id: A0A0A2SLT0
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS08835
gene id: 198467:AFK25_RS08835
uniprot id: A0A0A2SHL6
names: Similarity
messages: Belongs to the UPF0302 family.

198467:AFK25 RS05315
gene id: 198467:AFK25_RS05315
uniprot id: M5QYD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

198467:AFK25 RS03305
gene id: 198467:AFK25_RS03305
uniprot id: M5QU00
names: Similarity
messages: Belongs to the UPF0234 family.

198467:AFK25 RS04730
gene id: 198467:AFK25_RS04730
uniprot id: A0A0A2SQ67
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

198467:AFK25 RS03255
gene id: 198467:AFK25_RS03255
uniprot id: A0A0A2SP82
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

198467:AFK25 RS05495
gene id: 198467:AFK25_RS05495
uniprot id: M5R955
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

198467:AFK25 RS00080
gene id: 198467:AFK25_RS00080
uniprot id: M5R8S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

198467:AFK25 RS12515
gene id: 198467:AFK25_RS12515
uniprot id: A0A0A2SG49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS10940
gene id: 198467:AFK25_RS10940
uniprot id: A0A0A2T1F4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

198467:AFK25 RS10820
gene id: 198467:AFK25_RS10820
uniprot id: M5QSQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

198467:AFK25 RS11290
gene id: 198467:AFK25_RS11290
uniprot id: A0A0A2SKC4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

198467:AFK25 RS09420
gene id: 198467:AFK25_RS09420
uniprot id: M5QSR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

198467:AFK25 RS11780
gene id: 198467:AFK25_RS11780
uniprot id: M5QU03
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

198467:AFK25 RS10120
gene id: 198467:AFK25_RS10120
uniprot id: A0A0A2SKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

198467:AFK25 RS01905
gene id: 198467:AFK25_RS01905
uniprot id: A0A0A2SMP5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

198467:AFK25 RS05960
gene id: 198467:AFK25_RS05960
uniprot id: A0A0A2SMA4
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

198467:AFK25 RS02730
gene id: 198467:AFK25_RS02730
uniprot id: M5QS24
names: Subcellular Location Annotation
messages: Cell membrane

198467:AFK25 RS10380
gene id: 198467:AFK25_RS10380
uniprot id: M5QQY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

198467:AFK25 RS02665
gene id: 198467:AFK25_RS02665
uniprot id: A0A0A2SPV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

198467:AFK25 RS14200
gene id: 198467:AFK25_RS14200
uniprot id: A0A0A2SKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

198467:AFK25 RS14825
gene id: 198467:AFK25_RS14825
uniprot id: M5QQT3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS06455
gene id: 198467:AFK25_RS06455
uniprot id: M5QWA2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

198467:AFK25 RS03430
gene id: 198467:AFK25_RS03430
uniprot id: A0A0A2SLC4
names: Similarity
messages: Belongs to the UPF0736 family.

198467:AFK25 RS14280
gene id: 198467:AFK25_RS14280
uniprot id: A0A0A2SKK6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

198467:AFK25 RS11640
gene id: 198467:AFK25_RS11640
uniprot id: A0A0A2SK57
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

198467:AFK25 RS04395
gene id: 198467:AFK25_RS04395
uniprot id: A0A0A2SR94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

198467:AFK25 RS09400
gene id: 198467:AFK25_RS09400
uniprot id: A0A0A2SL24
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

198467:AFK25 RS02975
gene id: 198467:AFK25_RS02975
uniprot id: A0A0A2T238
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS12000
gene id: 198467:AFK25_RS12000
uniprot id: M5QTD2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

198467:AFK25 RS00565
gene id: 198467:AFK25_RS00565
uniprot id: M5R6K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

198467:AFK25 RS13880
gene id: 198467:AFK25_RS13880
uniprot id: A0A0A2T2Y4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

198467:AFK25 RS08290
gene id: 198467:AFK25_RS08290
uniprot id: A0A0A2SFV1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

198467:AFK25 RS14605
gene id: 198467:AFK25_RS14605
uniprot id: M5RBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ParB family.
messages: Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
messages: nucleoid

198467:AFK25 RS10935
gene id: 198467:AFK25_RS10935
uniprot id: A0A0A2SP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

198467:AFK25 RS07280
gene id: 198467:AFK25_RS07280
uniprot id: A0A0A2SID1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

198467:AFK25 RS07760
gene id: 198467:AFK25_RS07760
uniprot id: A0A0A2SM04
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

198467:AFK25 RS01700
gene id: 198467:AFK25_RS01700
uniprot id: M5R8B6
names: Similarity
messages: Belongs to the acylphosphatase family.

198467:AFK25 RS06665
gene id: 198467:AFK25_RS06665
uniprot id: A0A0A2SNK6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

198467:AFK25 RS10585
gene id: 198467:AFK25_RS10585
uniprot id: A0A0A2SKE1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

198467:AFK25 RS02995
gene id: 198467:AFK25_RS02995
uniprot id: A0A0A2SP45
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

198467:AFK25 RS10135
gene id: 198467:AFK25_RS10135
uniprot id: M5QRJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

198467:AFK25 RS04785
gene id: 198467:AFK25_RS04785
uniprot id: M5QRN3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS14395
gene id: 198467:AFK25_RS14395
uniprot id: A0A0A2SQD8
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

198467:AFK25 RS02735
gene id: 198467:AFK25_RS02735
uniprot id: M5R4X2
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

198467:AFK25 RS04500
gene id: 198467:AFK25_RS04500
uniprot id: M5QPK2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

198467:AFK25 RS11340
gene id: 198467:AFK25_RS11340
uniprot id: A0A0A2SJ30
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS13185
gene id: 198467:AFK25_RS13185
uniprot id: A0A0A2T000
names: Similarity
messages: Belongs to the polysaccharide synthase family.

198467:AFK25 RS08310
gene id: 198467:AFK25_RS08310
uniprot id: A0A0A2SIR0
names: Similarity
messages: Belongs to the glutamate synthase family.

198467:AFK25 RS14205
gene id: 198467:AFK25_RS14205
uniprot id: A0A0A2SQI2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

198467:AFK25 RS10640
gene id: 198467:AFK25_RS10640
uniprot id: A0A0A2SKF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

198467:AFK25 RS09405
gene id: 198467:AFK25_RS09405
uniprot id: M5QQH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

198467:AFK25 RS09240
gene id: 198467:AFK25_RS09240
uniprot id: A0A0A2SYA8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

198467:AFK25 RS00470
gene id: 198467:AFK25_RS00470
uniprot id: A0A0A2SI19
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

198467:AFK25 RS11380
gene id: 198467:AFK25_RS11380
uniprot id: M4HQI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

198467:AFK25 RS07670
gene id: 198467:AFK25_RS07670
uniprot id: A0A0A2SI73
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

198467:AFK25 RS09495
gene id: 198467:AFK25_RS09495
uniprot id: A0A0A2SK71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

198467:AFK25 RS09165
gene id: 198467:AFK25_RS09165
uniprot id: A0A0A2SYC0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

198467:AFK25 RS11985
gene id: 198467:AFK25_RS11985
uniprot id: M5QVI9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS05720
gene id: 198467:AFK25_RS05720
uniprot id: A0A0A2T0I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

198467:AFK25 RS08470
gene id: 198467:AFK25_RS08470
uniprot id: A0A0A2SIT8
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS13705
gene id: 198467:AFK25_RS13705
uniprot id: A0A0A2SQ20
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

198467:AFK25 RS04380
gene id: 198467:AFK25_RS04380
uniprot id: A0A0A2SMF3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type IV subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
messages: Has no RuBP-carboxylation activity.
messages: Homodimer.

198467:AFK25 RS10325
gene id: 198467:AFK25_RS10325
uniprot id: M5R3R8
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS08030
gene id: 198467:AFK25_RS08030
uniprot id: M5QV76
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

198467:AFK25 RS03355
gene id: 198467:AFK25_RS03355
uniprot id: A0A0A2SK69
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

198467:AFK25 RS13795
gene id: 198467:AFK25_RS13795
uniprot id: M5QX03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

198467:AFK25 RS08885
gene id: 198467:AFK25_RS08885
uniprot id: A0A0A2SHK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

198467:AFK25 RS08570
gene id: 198467:AFK25_RS08570
uniprot id: A0A0A2SLL8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

198467:AFK25 RS14290
gene id: 198467:AFK25_RS14290
uniprot id: A0A0A2T2P5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

198467:AFK25 RS11350
gene id: 198467:AFK25_RS11350
uniprot id: A0A0A2T173
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

198467:AFK25 RS08705
gene id: 198467:AFK25_RS08705
uniprot id: A0A0A2SYL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS13805
gene id: 198467:AFK25_RS13805
uniprot id: A0A0A2SM20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

198467:AFK25 RS09935
gene id: 198467:AFK25_RS09935
uniprot id: A0A0A2SJZ3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

198467:AFK25 RS07110
gene id: 198467:AFK25_RS07110
uniprot id: M5QU13
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

198467:AFK25 RS03025
gene id: 198467:AFK25_RS03025
uniprot id: A0A0A2SL65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

198467:AFK25 RS11050
gene id: 198467:AFK25_RS11050
uniprot id: A0A0A2SNC9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

198467:AFK25 RS03020
gene id: 198467:AFK25_RS03020
uniprot id: A0A0A2SP48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

198467:AFK25 RS14010
gene id: 198467:AFK25_RS14010
uniprot id: A0A0A2SLY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS14185
gene id: 198467:AFK25_RS14185
uniprot id: A0A0A2SKX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

198467:AFK25 RS03535
gene id: 198467:AFK25_RS03535
uniprot id: A0A0A2SQ59
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

198467:AFK25 RS06005
gene id: 198467:AFK25_RS06005
uniprot id: A0A0A2T091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS05325
gene id: 198467:AFK25_RS05325
uniprot id: A0A0A2SNJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

198467:AFK25 RS03325
gene id: 198467:AFK25_RS03325
uniprot id: M5QTZ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS14190
gene id: 198467:AFK25_RS14190
uniprot id: A0A0A2SLV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

198467:AFK25 RS10955
gene id: 198467:AFK25_RS10955
uniprot id: A0A0A2SJ96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

198467:AFK25 RS05985
gene id: 198467:AFK25_RS05985
uniprot id: M5QQ61
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS10225
gene id: 198467:AFK25_RS10225
uniprot id: A0A0A2SKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

198467:AFK25 RS14195
gene id: 198467:AFK25_RS14195
uniprot id: A0A0A2SPS0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

198467:AFK25 RS00970
gene id: 198467:AFK25_RS00970
uniprot id: A0A0A2SIL3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS12875
gene id: 198467:AFK25_RS12875
uniprot id: M5QRB1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

198467:AFK25 RS10250
gene id: 198467:AFK25_RS10250
uniprot id: M5R3Q5
names: PTM
messages: Binds 1 heme c group covalently per subunit.

198467:AFK25 RS05265
gene id: 198467:AFK25_RS05265
uniprot id: A0A0A2SMP3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

198467:AFK25 RS00525
gene id: 198467:AFK25_RS00525
uniprot id: A0A0A2SKY4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

198467:AFK25 RS14570
gene id: 198467:AFK25_RS14570
uniprot id: M5R804
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

198467:AFK25 RS11140
gene id: 198467:AFK25_RS11140
uniprot id: M5QV36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

198467:AFK25 RS07690
gene id: 198467:AFK25_RS07690
uniprot id: A0A0A2SZ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

198467:AFK25 RS14425
gene id: 198467:AFK25_RS14425
uniprot id: A0A0A2T2M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS08985
gene id: 198467:AFK25_RS08985
uniprot id: A0A0A2SYF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS06630
gene id: 198467:AFK25_RS06630
uniprot id: A0A0A2SPF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS08730
gene id: 198467:AFK25_RS08730
uniprot id: A0A0A2SYL1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

198467:AFK25 RS00705
gene id: 198467:AFK25_RS00705
uniprot id: M5QUL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

198467:AFK25 RS07800
gene id: 198467:AFK25_RS07800
uniprot id: M5R741
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS06710
gene id: 198467:AFK25_RS06710
uniprot id: A0A0A2SJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

198467:AFK25 RS09645
gene id: 198467:AFK25_RS09645
uniprot id: M5QRA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

198467:AFK25 RS02710
gene id: 198467:AFK25_RS02710
uniprot id: A0A0A2T206
names: Similarity
messages: Belongs to the ThiD family.

198467:AFK25 RS11445
gene id: 198467:AFK25_RS11445
uniprot id: A0A0A2SNX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

198467:AFK25 RS04970
gene id: 198467:AFK25_RS04970
uniprot id: M5QY60
names: Similarity
messages: Belongs to the UPF0358 family.

198467:AFK25 RS00120
gene id: 198467:AFK25_RS00120
uniprot id: A0A0A2SKH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

198467:AFK25 RS14100
gene id: 198467:AFK25_RS14100
uniprot id: M5RBM9
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

198467:AFK25 RS11820
gene id: 198467:AFK25_RS11820
uniprot id: M5QTA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

198467:AFK25 RS10320
gene id: 198467:AFK25_RS10320
uniprot id: M5QT76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

198467:AFK25 RS06870
gene id: 198467:AFK25_RS06870
uniprot id: A0A0A2SLH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

198467:AFK25 RS08075
gene id: 198467:AFK25_RS08075
uniprot id: A0A0A2SX92
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

198467:AFK25 RS08900
gene id: 198467:AFK25_RS08900
uniprot id: A0A0A2SLD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

198467:AFK25 RS05880
gene id: 198467:AFK25_RS05880
uniprot id: M5QXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

198467:AFK25 RS03215
gene id: 198467:AFK25_RS03215
uniprot id: A0A0A2T274
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS04800
gene id: 198467:AFK25_RS04800
uniprot id: A0A0A2T347
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

198467:AFK25 RS11620
gene id: 198467:AFK25_RS11620
uniprot id: M5R5Y5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS07045
gene id: 198467:AFK25_RS07045
uniprot id: A0A0A2SIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS10645
gene id: 198467:AFK25_RS10645
uniprot id: A0A0A2SFA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

198467:AFK25 RS01870
gene id: 198467:AFK25_RS01870
uniprot id: A0A0A2SQM1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

198467:AFK25 RS08875
gene id: 198467:AFK25_RS08875
uniprot id: A0A0A2SLD7
names: Similarity
messages: Belongs to the TrpC family.

198467:AFK25 RS10400
gene id: 198467:AFK25_RS10400
uniprot id: M5R3T2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

198467:AFK25 RS12255
gene id: 198467:AFK25_RS12255
uniprot id: A0A0A2SMU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

198467:AFK25 RS11700
gene id: 198467:AFK25_RS11700
uniprot id: A0A0A2SIW9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS12700
gene id: 198467:AFK25_RS12700
uniprot id: M5QRZ5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

198467:AFK25 RS14945
gene id: 198467:AFK25_RS14945
uniprot id: M5R7Z1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS05810
gene id: 198467:AFK25_RS05810
uniprot id: M5QYL9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS11760
gene id: 198467:AFK25_RS11760
uniprot id: A0A0A2SNT0
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS08890
gene id: 198467:AFK25_RS08890
uniprot id: A0A0A2SKH6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

198467:AFK25 RS05335
gene id: 198467:AFK25_RS05335
uniprot id: A0A0A2SJR2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS05105
gene id: 198467:AFK25_RS05105
uniprot id: M5QWX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

198467:AFK25 RS14050
gene id: 198467:AFK25_RS14050
uniprot id: M5QX39
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

198467:AFK25 RS00610
gene id: 198467:AFK25_RS00610
uniprot id: M5QVY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

198467:AFK25 RS02895
gene id: 198467:AFK25_RS02895
uniprot id: A0A0A2SL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS06765
gene id: 198467:AFK25_RS06765
uniprot id: A0A0A2SLI8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

198467:AFK25 RS06785
gene id: 198467:AFK25_RS06785
uniprot id: A0A0A2SIL1
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

198467:AFK25 RS00265
gene id: 198467:AFK25_RS00265
uniprot id: M5QWN1
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

198467:AFK25 RS07200
gene id: 198467:AFK25_RS07200
uniprot id: A0A0A2SLA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

198467:AFK25 RS05040
gene id: 198467:AFK25_RS05040
uniprot id: A0A7U4NNK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

198467:AFK25 RS03700
gene id: 198467:AFK25_RS03700
uniprot id: A0A0A2SPK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS12525
gene id: 198467:AFK25_RS12525
uniprot id: A0A0A2SJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

198467:AFK25 RS14535
gene id: 198467:AFK25_RS14535
uniprot id: M5QVY6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

198467:AFK25 RS01075
gene id: 198467:AFK25_RS01075
uniprot id: A0A0A2SIN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

198467:AFK25 RS00745
gene id: 198467:AFK25_RS00745
uniprot id: M5QTV2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

198467:AFK25 RS05270
gene id: 198467:AFK25_RS05270
uniprot id: M5R8Z1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

198467:AFK25 RS06425
gene id: 198467:AFK25_RS06425
uniprot id: A0A0A2SHW1
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS02145
gene id: 198467:AFK25_RS02145
uniprot id: A0A7U4NQM6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

198467:AFK25 RS11720
gene id: 198467:AFK25_RS11720
uniprot id: M5QT75
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

198467:AFK25 RS09790
gene id: 198467:AFK25_RS09790
uniprot id: M5QSY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

198467:AFK25 RS05625
gene id: 198467:AFK25_RS05625
uniprot id: A0A0A2SJM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

198467:AFK25 RS05450
gene id: 198467:AFK25_RS05450
uniprot id: M5QWZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

198467:AFK25 RS11415
gene id: 198467:AFK25_RS11415
uniprot id: A0A0A2SJ17
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS06970
gene id: 198467:AFK25_RS06970
uniprot id: A0A0A2SII5
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

198467:AFK25 RS04490
gene id: 198467:AFK25_RS04490
uniprot id: M5R1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

198467:AFK25 RS00480
gene id: 198467:AFK25_RS00480
uniprot id: A0A0A2SGS6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

198467:AFK25 RS02580
gene id: 198467:AFK25_RS02580
uniprot id: A0A0A2T1Y1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

198467:AFK25 RS04765
gene id: 198467:AFK25_RS04765
uniprot id: A0A0A2SR05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

198467:AFK25 RS07665
gene id: 198467:AFK25_RS07665
uniprot id: A0A0A2SZ54
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS01055
gene id: 198467:AFK25_RS01055
uniprot id: A0A0A2SFN8
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

198467:AFK25 RS13890
gene id: 198467:AFK25_RS13890
uniprot id: M5RBJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

198467:AFK25 RS13800
gene id: 198467:AFK25_RS13800
uniprot id: A0A0A2T2Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

198467:AFK25 RS11690
gene id: 198467:AFK25_RS11690
uniprot id: M5R604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

198467:AFK25 RS01435
gene id: 198467:AFK25_RS01435
uniprot id: A0A0A2SRM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds a copper B center.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Heme A3.
messages: Membrane

198467:AFK25 RS11460
gene id: 198467:AFK25_RS11460
uniprot id: A0A0A2SN58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

198467:AFK25 RS09980
gene id: 198467:AFK25_RS09980
uniprot id: A0A0A2SGZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS05815
gene id: 198467:AFK25_RS05815
uniprot id: M5R9B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

198467:AFK25 RS01310
gene id: 198467:AFK25_RS01310
uniprot id: A0A0A2T3X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

198467:AFK25 RS10855
gene id: 198467:AFK25_RS10855
uniprot id: M5R9B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

198467:AFK25 RS12075
gene id: 198467:AFK25_RS12075
uniprot id: A0A0A2SNP0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS04280
gene id: 198467:AFK25_RS04280
uniprot id: A0A0A2SQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS08625
gene id: 198467:AFK25_RS08625
uniprot id: A0A0A2SLK6
names: Similarity
messages: Belongs to the peptidase M29 family.

198467:AFK25 RS02700
gene id: 198467:AFK25_RS02700
uniprot id: M5R8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

198467:AFK25 RS11890
gene id: 198467:AFK25_RS11890
uniprot id: M5R651
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

198467:AFK25 RS05590
gene id: 198467:AFK25_RS05590
uniprot id: A0A0A2SNG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

198467:AFK25 RS02625
gene id: 198467:AFK25_RS02625
uniprot id: A0A0A2SNZ4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

198467:AFK25 RS12230
gene id: 198467:AFK25_RS12230
uniprot id: A0A0A2SMT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS08910
gene id: 198467:AFK25_RS08910
uniprot id: M5QQX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

198467:AFK25 RS00450
gene id: 198467:AFK25_RS00450
uniprot id: M5RA57
names: Similarity
messages: Belongs to the CtsR family.

198467:AFK25 RS01070
gene id: 198467:AFK25_RS01070
uniprot id: A0A0A2SEH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

198467:AFK25 RS05455
gene id: 198467:AFK25_RS05455
uniprot id: M5RCZ7
names: Similarity
messages: Belongs to the asp23 family.

198467:AFK25 RS08260
gene id: 198467:AFK25_RS08260
uniprot id: A0A0A2SWP8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

198467:AFK25 RS05825
gene id: 198467:AFK25_RS05825
uniprot id: M5RD63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

198467:AFK25 RS12770
gene id: 198467:AFK25_RS12770
uniprot id: A0A0A2SZV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

198467:AFK25 RS05250
gene id: 198467:AFK25_RS05250
uniprot id: A0A0A2SNK7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

198467:AFK25 RS05190
gene id: 198467:AFK25_RS05190
uniprot id: A0A0A2SMQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS13775
gene id: 198467:AFK25_RS13775
uniprot id: M5R5C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

198467:AFK25 RS01755
gene id: 198467:AFK25_RS01755
uniprot id: M5QW05
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

198467:AFK25 RS07050
gene id: 198467:AFK25_RS07050
uniprot id: A0A0A2SLD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

198467:AFK25 RS07085
gene id: 198467:AFK25_RS07085
uniprot id: M5QU08
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

198467:AFK25 RS07135
gene id: 198467:AFK25_RS07135
uniprot id: A0A0A2SM87
names: Similarity
messages: Belongs to the HypE family.

198467:AFK25 RS10105
gene id: 198467:AFK25_RS10105
uniprot id: A0A0A2SGX7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

198467:AFK25 RS07145
gene id: 198467:AFK25_RS07145
uniprot id: A0A0A2SIF0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

198467:AFK25 RS09145
gene id: 198467:AFK25_RS09145
uniprot id: M5QQC8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

198467:AFK25 RS03390
gene id: 198467:AFK25_RS03390
uniprot id: A0A0A2SPA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

198467:AFK25 RS08070
gene id: 198467:AFK25_RS08070
uniprot id: A0A0A2SGB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

198467:AFK25 RS01500
gene id: 198467:AFK25_RS01500
uniprot id: A0A0A2SMW0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

198467:AFK25 RS09175
gene id: 198467:AFK25_RS09175
uniprot id: A0A0A2SKC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

198467:AFK25 RS04880
gene id: 198467:AFK25_RS04880
uniprot id: A0A0A2T329
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

198467:AFK25 RS13770
gene id: 198467:AFK25_RS13770
uniprot id: M5QUR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

198467:AFK25 RS05120
gene id: 198467:AFK25_RS05120
uniprot id: M5QWJ0
names: Similarity
messages: Belongs to the peptidase S16 family.

198467:AFK25 RS04060
gene id: 198467:AFK25_RS04060
uniprot id: A0A0A2SEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

198467:AFK25 RS11500
gene id: 198467:AFK25_RS11500
uniprot id: M5QV73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

198467:AFK25 RS11195
gene id: 198467:AFK25_RS11195
uniprot id: M5QV44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

198467:AFK25 RS05510
gene id: 198467:AFK25_RS05510
uniprot id: A0A0A2T0L9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

198467:AFK25 RS09955
gene id: 198467:AFK25_RS09955
uniprot id: A0A0A2SH02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

198467:AFK25 RS13640
gene id: 198467:AFK25_RS13640
uniprot id: A0A0A2SIU3
names: Similarity
messages: Belongs to the FGGY kinase family.

198467:AFK25 RS11615
gene id: 198467:AFK25_RS11615
uniprot id: A0A0A2SK62
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

198467:AFK25 RS00665
gene id: 198467:AFK25_RS00665
uniprot id: M5R6M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

198467:AFK25 RS11145
gene id: 198467:AFK25_RS11145
uniprot id: A0A0A2T1B1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

198467:AFK25 RS02605
gene id: 198467:AFK25_RS02605
uniprot id: A0A0A2SL07
names: Similarity
messages: Belongs to the phosphohexose mutase family.

198467:AFK25 RS07015
gene id: 198467:AFK25_RS07015
uniprot id: A0A0A2SZE4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

198467:AFK25 RS06285
gene id: 198467:AFK25_RS06285
uniprot id: A0A0A2SM35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

198467:AFK25 RS02650
gene id: 198467:AFK25_RS02650
uniprot id: A0A0A2SNZ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

198467:AFK25 RS01495
gene id: 198467:AFK25_RS01495
uniprot id: A0A0A2T3U4
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

198467:AFK25 RS09315
gene id: 198467:AFK25_RS09315
uniprot id: A0A0A2SG39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

198467:AFK25 RS05755
gene id: 198467:AFK25_RS05755
uniprot id: A0A0A2SME4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

198467:AFK25 RS04610
gene id: 198467:AFK25_RS04610
uniprot id: A0A0A2SMB2
names: Similarity
messages: Belongs to the peptidase C40 family.

198467:AFK25 RS12960
gene id: 198467:AFK25_RS12960
uniprot id: M5R7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

198467:AFK25 RS08270
gene id: 198467:AFK25_RS08270
uniprot id: A0A0A2SEJ5
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS00930
gene id: 198467:AFK25_RS00930
uniprot id: A0A0A2SJF2
names: Similarity
messages: Belongs to the EamA transporter family.

198467:AFK25 RS09925
gene id: 198467:AFK25_RS09925
uniprot id: M5QQR1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

198467:AFK25 RS05650
gene id: 198467:AFK25_RS05650
uniprot id: A0A0A2SJL9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

198467:AFK25 RS10060
gene id: 198467:AFK25_RS10060
uniprot id: A0A0A2SJW9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

198467:AFK25 RS03210
gene id: 198467:AFK25_RS03210
uniprot id: A0A0A2SL91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

198467:AFK25 RS01625
gene id: 198467:AFK25_RS01625
uniprot id: A0A0A2SQI7
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS00295
gene id: 198467:AFK25_RS00295
uniprot id: A0A0A2SWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

198467:AFK25 RS03185
gene id: 198467:AFK25_RS03185
uniprot id: A0A0A2T270
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

198467:AFK25 RS00910
gene id: 198467:AFK25_RS00910
uniprot id: A0A0A2SED8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

198467:AFK25 RS03310
gene id: 198467:AFK25_RS03310
uniprot id: A0A0A2SPK3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

198467:AFK25 RS08845
gene id: 198467:AFK25_RS08845
uniprot id: A0A0A2SGB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

198467:AFK25 RS11250
gene id: 198467:AFK25_RS11250
uniprot id: A0A0A2SJ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

198467:AFK25 RS07460
gene id: 198467:AFK25_RS07460
uniprot id: A0A0A2SL72
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS10805
gene id: 198467:AFK25_RS10805
uniprot id: A0A0A2SFH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

198467:AFK25 RS07640
gene id: 198467:AFK25_RS07640
uniprot id: M5QV04
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspN family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

198467:AFK25 RS13995
gene id: 198467:AFK25_RS13995
uniprot id: A0A0A2SKQ6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

198467:AFK25 RS08120
gene id: 198467:AFK25_RS08120
uniprot id: A0A0A2SGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

198467:AFK25 RS08010
gene id: 198467:AFK25_RS08010
uniprot id: A0A0A2SF14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS13090
gene id: 198467:AFK25_RS13090
uniprot id: A0A0A2SHK3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS00680
gene id: 198467:AFK25_RS00680
uniprot id: M5QUK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

198467:AFK25 RS10890
gene id: 198467:AFK25_RS10890
uniprot id: M5QUZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS11455
gene id: 198467:AFK25_RS11455
uniprot id: A0A0A2SK95
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

198467:AFK25 RS09835
gene id: 198467:AFK25_RS09835
uniprot id: A0A0A2SK09
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

198467:AFK25 RS13680
gene id: 198467:AFK25_RS13680
uniprot id: A0A0A2SQ26
names: Similarity
messages: Belongs to the UDPGP type 2 family.

198467:AFK25 RS00880
gene id: 198467:AFK25_RS00880
uniprot id: M5QRJ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

198467:AFK25 RS00180
gene id: 198467:AFK25_RS00180
uniprot id: M5R8L7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

198467:AFK25 RS02540
gene id: 198467:AFK25_RS02540
uniprot id: M5QUE3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

198467:AFK25 RS10530
gene id: 198467:AFK25_RS10530
uniprot id: A0A0A2SGS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

198467:AFK25 RS13810
gene id: 198467:AFK25_RS13810
uniprot id: M5RBH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

198467:AFK25 RS12685
gene id: 198467:AFK25_RS12685
uniprot id: A0A0A2SLZ5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

198467:AFK25 RS08750
gene id: 198467:AFK25_RS08750
uniprot id: M5QQ40
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

198467:AFK25 RS04645
gene id: 198467:AFK25_RS04645
uniprot id: A0A0A2SL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

198467:AFK25 RS00430
gene id: 198467:AFK25_RS00430
uniprot id: A0A0A2SJ77
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS10010
gene id: 198467:AFK25_RS10010
uniprot id: A0A0A2SJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

198467:AFK25 RS00695
gene id: 198467:AFK25_RS00695
uniprot id: A0A0A2SHW8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

198467:AFK25 RS03275
gene id: 198467:AFK25_RS03275
uniprot id: A0A0A2SK54
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

198467:AFK25 RS11735
gene id: 198467:AFK25_RS11735
uniprot id: M5QVC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS13070
gene id: 198467:AFK25_RS13070
uniprot id: A0A0A2SMJ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS12670
gene id: 198467:AFK25_RS12670
uniprot id: A0A0A2SLX2
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS10435
gene id: 198467:AFK25_RS10435
uniprot id: A0A0A2SJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

198467:AFK25 RS09235
gene id: 198467:AFK25_RS09235
uniprot id: A0A0A2SL55
names: Similarity
messages: Belongs to the peptidase S11 family.

198467:AFK25 RS06910
gene id: 198467:AFK25_RS06910
uniprot id: M5RAG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

198467:AFK25 RS00385
gene id: 198467:AFK25_RS00385
uniprot id: M5QW67
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

198467:AFK25 RS00085
gene id: 198467:AFK25_RS00085
uniprot id: A0A0A2SQC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

198467:AFK25 RS05430
gene id: 198467:AFK25_RS05430
uniprot id: M5RCZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

198467:AFK25 RS08275
gene id: 198467:AFK25_RS08275
uniprot id: A0A0A2SIQ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

198467:AFK25 RS13755
gene id: 198467:AFK25_RS13755
uniprot id: A0A0A2SQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

198467:AFK25 RS03485
gene id: 198467:AFK25_RS03485
uniprot id: M5QTU2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
messages: Homodimer.
messages: The N-terminal domain has binding sites for ComK and probably for unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

198467:AFK25 RS14175
gene id: 198467:AFK25_RS14175
uniprot id: A0A0A2SQI9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

198467:AFK25 RS05685
gene id: 198467:AFK25_RS05685
uniprot id: A0A0A2SIC1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

198467:AFK25 RS06995
gene id: 198467:AFK25_RS06995
uniprot id: A0A0A2SII0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

198467:AFK25 RS00900
gene id: 198467:AFK25_RS00900
uniprot id: M5QPZ3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

198467:AFK25 RS11850
gene id: 198467:AFK25_RS11850
uniprot id: A0A0A2T0Z0
names: Similarity
messages: Belongs to the histone deacetylase family.

198467:AFK25 RS12885
gene id: 198467:AFK25_RS12885
uniprot id: A0A0A2SHN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

198467:AFK25 RS01360
gene id: 198467:AFK25_RS01360
uniprot id: M5QWC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

198467:AFK25 RS11560
gene id: 198467:AFK25_RS11560
uniprot id: A0A0A2T139
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

198467:AFK25 RS05980
gene id: 198467:AFK25_RS05980
uniprot id: M5R600
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS00750
gene id: 198467:AFK25_RS00750
uniprot id: A0A0A2SKT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS09595
gene id: 198467:AFK25_RS09595
uniprot id: A0A0A2SH72
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

198467:AFK25 RS07195
gene id: 198467:AFK25_RS07195
uniprot id: A0A0A2SIE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

198467:AFK25 RS14170
gene id: 198467:AFK25_RS14170
uniprot id: A0A0A2SKM2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS11300
gene id: 198467:AFK25_RS11300
uniprot id: M5R5T8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

198467:AFK25 RS02820
gene id: 198467:AFK25_RS02820
uniprot id: M5R8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SscA family.
messages: Membrane

198467:AFK25 RS07480
gene id: 198467:AFK25_RS07480
uniprot id: M5R6Y7
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS00500
gene id: 198467:AFK25_RS00500
uniprot id: A0A0A2SKY9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS12840
gene id: 198467:AFK25_RS12840
uniprot id: M5R7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

198467:AFK25 RS10985
gene id: 198467:AFK25_RS10985
uniprot id: A0A0A2SP86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

198467:AFK25 RS03555
gene id: 198467:AFK25_RS03555
uniprot id: A0A0A2SLF2
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS08430
gene id: 198467:AFK25_RS08430
uniprot id: A0A0A2SWS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

198467:AFK25 RS11975
gene id: 198467:AFK25_RS11975
uniprot id: A0A0A2SNQ4
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS00390
gene id: 198467:AFK25_RS00390
uniprot id: M5R8H8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

198467:AFK25 RS00465
gene id: 198467:AFK25_RS00465
uniprot id: M5R6F5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

198467:AFK25 RS03460
gene id: 198467:AFK25_RS03460
uniprot id: A0A0A2T2B5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

198467:AFK25 RS11565
gene id: 198467:AFK25_RS11565
uniprot id: A0A0A2SK72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

198467:AFK25 RS01305
gene id: 198467:AFK25_RS01305
uniprot id: M5QWS3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

198467:AFK25 RS10990
gene id: 198467:AFK25_RS10990
uniprot id: A0A0A2T1E3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

198467:AFK25 RS13180
gene id: 198467:AFK25_RS13180
uniprot id: A0A0A2SHJ0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

198467:AFK25 RS11155
gene id: 198467:AFK25_RS11155
uniprot id: M5R9H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

198467:AFK25 RS07150
gene id: 198467:AFK25_RS07150
uniprot id: A0A0A2SLB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

198467:AFK25 RS13695
gene id: 198467:AFK25_RS13695
uniprot id: A0A0A2T316
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

198467:AFK25 RS07360
gene id: 198467:AFK25_RS07360
uniprot id: A0A0A2SM61
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).
messages: The active site is a redox-active disulfide bond.

198467:AFK25 RS13715
gene id: 198467:AFK25_RS13715
uniprot id: A0A0A2SQV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

198467:AFK25 RS07970
gene id: 198467:AFK25_RS07970
uniprot id: A0A0A2SG93
names: Subcellular Location Annotation
messages: Cell membrane

198467:AFK25 RS10745
gene id: 198467:AFK25_RS10745
uniprot id: M5QSP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS07840
gene id: 198467:AFK25_RS07840
uniprot id: A0A0A2SX45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS05855
gene id: 198467:AFK25_RS05855
uniprot id: M5QXF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

198467:AFK25 RS07405
gene id: 198467:AFK25_RS07405
uniprot id: A0A0A2SL79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

198467:AFK25 RS03920
gene id: 198467:AFK25_RS03920
uniprot id: A0A0A2SIH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

198467:AFK25 RS11160
gene id: 198467:AFK25_RS11160
uniprot id: M5QTN7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS11030
gene id: 198467:AFK25_RS11030
uniprot id: A0A0A2SJ83
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

198467:AFK25 RS06410
gene id: 198467:AFK25_RS06410
uniprot id: A0A0A2T020
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS01720
gene id: 198467:AFK25_RS01720
uniprot id: A0A0A2SLI4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

198467:AFK25 RS09745
gene id: 198467:AFK25_RS09745
uniprot id: A0A0A2SKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

198467:AFK25 RS10900
gene id: 198467:AFK25_RS10900
uniprot id: M5QSS0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

198467:AFK25 RS12235
gene id: 198467:AFK25_RS12235
uniprot id: M5QUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

198467:AFK25 RS12935
gene id: 198467:AFK25_RS12935
uniprot id: A0A0A2SLS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

198467:AFK25 RS00595
gene id: 198467:AFK25_RS00595
uniprot id: A0A0A2SHZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

198467:AFK25 RS00505
gene id: 198467:AFK25_RS00505
uniprot id: M5QVW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

198467:AFK25 RS08960
gene id: 198467:AFK25_RS08960
uniprot id: A0A0A2SYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

198467:AFK25 RS07530
gene id: 198467:AFK25_RS07530
uniprot id: M5RAS5
names: Similarity
messages: Belongs to the manganese catalase family.

198467:AFK25 RS10170
gene id: 198467:AFK25_RS10170
uniprot id: A0A0A2SFQ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

198467:AFK25 RS13410
gene id: 198467:AFK25_RS13410
uniprot id: A0A0A2SJR3
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS12245
gene id: 198467:AFK25_RS12245
uniprot id: A0A0A2SLQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS03115
gene id: 198467:AFK25_RS03115
uniprot id: A0A0A2SQ08
names: Similarity
messages: Belongs to the asparagine synthetase family.

198467:AFK25 RS12110
gene id: 198467:AFK25_RS12110
uniprot id: A0A0A2SRI5
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS05115
gene id: 198467:AFK25_RS05115
uniprot id: A0A0A2SNM2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS00550
gene id: 198467:AFK25_RS00550
uniprot id: M5RAA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

198467:AFK25 RS07545
gene id: 198467:AFK25_RS07545
uniprot id: A0A0A2SL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS12300
gene id: 198467:AFK25_RS12300
uniprot id: A0A0A2SQU1
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS13620
gene id: 198467:AFK25_RS13620
uniprot id: A0A0A2SJM0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

198467:AFK25 RS06395
gene id: 198467:AFK25_RS06395
uniprot id: M5RC32
names: Similarity
messages: Belongs to the pirin family.

198467:AFK25 RS04635
gene id: 198467:AFK25_RS04635
uniprot id: M5QVG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

198467:AFK25 RS07090
gene id: 198467:AFK25_RS07090
uniprot id: M5RAK1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

198467:AFK25 RS07755
gene id: 198467:AFK25_RS07755
uniprot id: A0A0A2SGW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

198467:AFK25 RS09320
gene id: 198467:AFK25_RS09320
uniprot id: A0A0A2SL38
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

198467:AFK25 RS07615
gene id: 198467:AFK25_RS07615
uniprot id: M5QV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

198467:AFK25 RS01325
gene id: 198467:AFK25_RS01325
uniprot id: M5QY25
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

198467:AFK25 RS13820
gene id: 198467:AFK25_RS13820
uniprot id: M5QX08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

198467:AFK25 RS12250
gene id: 198467:AFK25_RS12250
uniprot id: A0A0A2SQT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

198467:AFK25 RS11220
gene id: 198467:AFK25_RS11220
uniprot id: M5QV48
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

198467:AFK25 RS08280
gene id: 198467:AFK25_RS08280
uniprot id: A0A0A2SFR7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

198467:AFK25 RS10885
gene id: 198467:AFK25_RS10885
uniprot id: A0A0A2SPB3
names: Similarity
messages: Belongs to the UPF0735 family.

198467:AFK25 RS00905
gene id: 198467:AFK25_RS00905
uniprot id: A0A0A2SJD9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS11570
gene id: 198467:AFK25_RS11570
uniprot id: A0A0A2SN40
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS13325
gene id: 198467:AFK25_RS13325
uniprot id: A0A0A2SMF0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

198467:AFK25 RS06400
gene id: 198467:AFK25_RS06400
uniprot id: M5QW93
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS03695
gene id: 198467:AFK25_RS03695
uniprot id: A0A0A2SQ78
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

198467:AFK25 RS04285
gene id: 198467:AFK25_RS04285
uniprot id: M5R2G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS11675
gene id: 198467:AFK25_RS11675
uniprot id: M5QT65
names: Similarity
messages: Belongs to the UPF0173 family.

198467:AFK25 RS01380
gene id: 198467:AFK25_RS01380
uniprot id: A0A0A2SLU5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

198467:AFK25 RS05415
gene id: 198467:AFK25_RS05415
uniprot id: M5QYF4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

198467:AFK25 RS06195
gene id: 198467:AFK25_RS06195
uniprot id: A0A0A2SM52
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS13030
gene id: 198467:AFK25_RS13030
uniprot id: A0A0A2SIU2
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS11320
gene id: 198467:AFK25_RS11320
uniprot id: A0A0A2SKC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

198467:AFK25 RS10355
gene id: 198467:AFK25_RS10355
uniprot id: M5QQY2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

198467:AFK25 RS00415
gene id: 198467:AFK25_RS00415
uniprot id: M5R8H3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

198467:AFK25 RS11510
gene id: 198467:AFK25_RS11510
uniprot id: A0A0A2SK84
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS01800
gene id: 198467:AFK25_RS01800
uniprot id: A0A0A2SQQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

198467:AFK25 RS13120
gene id: 198467:AFK25_RS13120
uniprot id: M5R2I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

198467:AFK25 RS11190
gene id: 198467:AFK25_RS11190
uniprot id: A0A0A2SNA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

198467:AFK25 RS07775
gene id: 198467:AFK25_RS07775
uniprot id: A0A7U4NRQ2
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

198467:AFK25 RS11120
gene id: 198467:AFK25_RS11120
uniprot id: A0A0A2T1B7
names: Similarity
messages: Belongs to the peptidase S16 family.

198467:AFK25 RS05085
gene id: 198467:AFK25_RS05085
uniprot id: M5QY81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

198467:AFK25 RS12600
gene id: 198467:AFK25_RS12600
uniprot id: A0A0A2SZY8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

198467:AFK25 RS04940
gene id: 198467:AFK25_RS04940
uniprot id: A0A0A2SJ71
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

198467:AFK25 RS04835
gene id: 198467:AFK25_RS04835
uniprot id: M5QRP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

198467:AFK25 RS12465
gene id: 198467:AFK25_RS12465
uniprot id: A0A0A2SJW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS07895
gene id: 198467:AFK25_RS07895
uniprot id: A0A0A2SK16
names: Similarity
messages: Belongs to the glutathione peroxidase family.

198467:AFK25 RS13945
gene id: 198467:AFK25_RS13945
uniprot id: M5QVP0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

198467:AFK25 RS14775
gene id: 198467:AFK25_RS14775
uniprot id: M5QVJ8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS13220
gene id: 198467:AFK25_RS13220
uniprot id: A0A0A2SMG7
names: Similarity
messages: Belongs to the bacterial flagellin family.

198467:AFK25 RS10155
gene id: 198467:AFK25_RS10155
uniprot id: M5R7E5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

198467:AFK25 RS09030
gene id: 198467:AFK25_RS09030
uniprot id: A0A0A2SG89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS04345
gene id: 198467:AFK25_RS04345
uniprot id: A0A0A2SRA0
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS05020
gene id: 198467:AFK25_RS05020
uniprot id: A0A0A2T1M3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS04400
gene id: 198467:AFK25_RS04400
uniprot id: M5R2I2
names: Similarity
messages: Belongs to the EamA transporter family.

198467:AFK25 RS09575
gene id: 198467:AFK25_RS09575
uniprot id: A0A0A2SK58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

198467:AFK25 RS01485
gene id: 198467:AFK25_RS01485
uniprot id: A0A0A2SRL8
names: Similarity
messages: Belongs to the OsmC/Ohr family.

198467:AFK25 RS11710
gene id: 198467:AFK25_RS11710
uniprot id: M5QVB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

198467:AFK25 RS04850
gene id: 198467:AFK25_RS04850
uniprot id: A0A0A2T333
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

198467:AFK25 RS04725
gene id: 198467:AFK25_RS04725
uniprot id: A0A0A2SM88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS01080
gene id: 198467:AFK25_RS01080
uniprot id: M5R2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

198467:AFK25 RS13615
gene id: 198467:AFK25_RS13615
uniprot id: A0A0A2SEN4
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS00730
gene id: 198467:AFK25_RS00730
uniprot id: M5QUL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

198467:AFK25 RS05675
gene id: 198467:AFK25_RS05675
uniprot id: A0A0A2SJL5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS05125
gene id: 198467:AFK25_RS05125
uniprot id: A0A0A2SJU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS05215
gene id: 198467:AFK25_RS05215
uniprot id: M5QYA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

198467:AFK25 RS12225
gene id: 198467:AFK25_RS12225
uniprot id: M5QVQ0
names: Similarity
messages: Belongs to the UPF0751 family.

198467:AFK25 RS03260
gene id: 198467:AFK25_RS03260
uniprot id: A0A0A2SL97
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

198467:AFK25 RS01615
gene id: 198467:AFK25_RS01615
uniprot id: A0A0A2SRD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS14830
gene id: 198467:AFK25_RS14830
uniprot id: M5QQY7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS13625
gene id: 198467:AFK25_RS13625
uniprot id: A0A0A2SWT7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

198467:AFK25 RS00790
gene id: 198467:AFK25_RS00790
uniprot id: A0A0A2SYS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

198467:AFK25 RS01280
gene id: 198467:AFK25_RS01280
uniprot id: M5QWS7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

198467:AFK25 RS14595
gene id: 198467:AFK25_RS14595
uniprot id: A0A0A2SKB7
names: Similarity
messages: Belongs to the ParB family.

198467:AFK25 RS00635
gene id: 198467:AFK25_RS00635
uniprot id: M5QVY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

198467:AFK25 RS05185
gene id: 198467:AFK25_RS05185
uniprot id: A0A0A2SNN7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS09210
gene id: 198467:AFK25_RS09210
uniprot id: A0A0A2SL61
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS13160
gene id: 198467:AFK25_RS13160
uniprot id: A0A0A2SZN7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

198467:AFK25 RS03565
gene id: 198467:AFK25_RS03565
uniprot id: A0A0A2T2D1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

198467:AFK25 RS08790
gene id: 198467:AFK25_RS08790
uniprot id: M5QSE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

198467:AFK25 RS10565
gene id: 198467:AFK25_RS10565
uniprot id: A0A7U4NQM6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

198467:AFK25 RS08770
gene id: 198467:AFK25_RS08770
uniprot id: A0A0A2SGD1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

198467:AFK25 RS06815
gene id: 198467:AFK25_RS06815
uniprot id: A0A0A2SLJ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

198467:AFK25 RS06715
gene id: 198467:AFK25_RS06715
uniprot id: M5QPR2
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

198467:AFK25 RS07320
gene id: 198467:AFK25_RS07320
uniprot id: A0A0A2SM64
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

198467:AFK25 RS05940
gene id: 198467:AFK25_RS05940
uniprot id: A0A0A2SI36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

198467:AFK25 RS00530
gene id: 198467:AFK25_RS00530
uniprot id: M5QUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

198467:AFK25 RS07715
gene id: 198467:AFK25_RS07715
uniprot id: M5QWH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

198467:AFK25 RS10500
gene id: 198467:AFK25_RS10500
uniprot id: A0A0A2SXQ5
names: Similarity
messages: Belongs to the MotB family.

198467:AFK25 RS04925
gene id: 198467:AFK25_RS04925
uniprot id: M5R5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS04135
gene id: 198467:AFK25_RS04135
uniprot id: A0A0A2SET3
names: Similarity
messages: Belongs to the EamA transporter family.

198467:AFK25 RS11175
gene id: 198467:AFK25_RS11175
uniprot id: M5QSX6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

198467:AFK25 RS06575
gene id: 198467:AFK25_RS06575
uniprot id: A0A0A2SIJ4
names: Similarity
messages: Belongs to the arginase family.

198467:AFK25 RS14390
gene id: 198467:AFK25_RS14390
uniprot id: A0A0A2SKJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS04825
gene id: 198467:AFK25_RS04825
uniprot id: M5R5X0
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

198467:AFK25 RS00980
gene id: 198467:AFK25_RS00980
uniprot id: A0A0A2SWL2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS00010
gene id: 198467:AFK25_RS00010
uniprot id: M5R817
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

198467:AFK25 RS00575
gene id: 198467:AFK25_RS00575
uniprot id: A0A0A2SKX4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.

198467:AFK25 RS09550
gene id: 198467:AFK25_RS09550
uniprot id: A0A0A2SK63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS10765
gene id: 198467:AFK25_RS10765
uniprot id: M5R5I9
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS08870
gene id: 198467:AFK25_RS08870
uniprot id: A0A0A2SGB5
names: Similarity
messages: Belongs to the TrpF family.

198467:AFK25 RS05610
gene id: 198467:AFK25_RS05610
uniprot id: A0A0A2SID4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

198467:AFK25 RS12070
gene id: 198467:AFK25_RS12070
uniprot id: M5RA12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

198467:AFK25 RS00760
gene id: 198467:AFK25_RS00760
uniprot id: A0A0A2SLR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

198467:AFK25 RS01750
gene id: 198467:AFK25_RS01750
uniprot id: A0A0A2SRI2
names: Similarity
messages: Belongs to the UPF0435 family.

198467:AFK25 RS14560
gene id: 198467:AFK25_RS14560
uniprot id: A0A0A2SXC9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

198467:AFK25 RS14235
gene id: 198467:AFK25_RS14235
uniprot id: A0A0A2T2Q7
names: Subcellular Location Annotation
messages: Cell membrane

198467:AFK25 RS09385
gene id: 198467:AFK25_RS09385
uniprot id: A0A0A2SHB2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

198467:AFK25 RS04720
gene id: 198467:AFK25_RS04720
uniprot id: A0A0A2T369
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS07065
gene id: 198467:AFK25_RS07065
uniprot id: A0A0A2SZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

198467:AFK25 RS07605
gene id: 198467:AFK25_RS07605
uniprot id: M5QU86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

198467:AFK25 RS14545
gene id: 198467:AFK25_RS14545
uniprot id: A0A0A2SF64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

198467:AFK25 RS01680
gene id: 198467:AFK25_RS01680
uniprot id: A0A0A2SML1
names: Similarity
messages: Belongs to the arginase family.

198467:AFK25 RS08880
gene id: 198467:AFK25_RS08880
uniprot id: A0A0A2SYH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS00485
gene id: 198467:AFK25_RS00485
uniprot id: A0A0A2SLX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

198467:AFK25 RS08300
gene id: 198467:AFK25_RS08300
uniprot id: A0A0A2SJI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS04190
gene id: 198467:AFK25_RS04190
uniprot id: M5QPI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

198467:AFK25 RS07075
gene id: 198467:AFK25_RS07075
uniprot id: M5QW59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

198467:AFK25 RS06500
gene id: 198467:AFK25_RS06500
uniprot id: A0A0A2SJC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS13490
gene id: 198467:AFK25_RS13490
uniprot id: A0A0A2SWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

198467:AFK25 RS07120
gene id: 198467:AFK25_RS07120
uniprot id: A0A0A2SIF5
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

198467:AFK25 RS01005
gene id: 198467:AFK25_RS01005
uniprot id: A0A0A2SWL7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

198467:AFK25 RS05405
gene id: 198467:AFK25_RS05405
uniprot id: A0A0A2T0N2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

198467:AFK25 RS10265
gene id: 198467:AFK25_RS10265
uniprot id: A0A0A2SJT7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

198467:AFK25 RS12575
gene id: 198467:AFK25_RS12575
uniprot id: M5R7R6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

198467:AFK25 RS12545
gene id: 198467:AFK25_RS12545
uniprot id: A0A0A2SX30
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS11080
gene id: 198467:AFK25_RS11080
uniprot id: A0A0A2SJ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

198467:AFK25 RS05205
gene id: 198467:AFK25_RS05205
uniprot id: A0A0A2T0R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS04310
gene id: 198467:AFK25_RS04310
uniprot id: A0A0A2SLC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

198467:AFK25 RS11870
gene id: 198467:AFK25_RS11870
uniprot id: M5QTA9
names: Similarity
messages: Belongs to the peptidase M29 family.

198467:AFK25 RS13855
gene id: 198467:AFK25_RS13855
uniprot id: A0A0A2T2Z0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

198467:AFK25 RS11365
gene id: 198467:AFK25_RS11365
uniprot id: A0A0A2SJ25
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

198467:AFK25 RS12880
gene id: 198467:AFK25_RS12880
uniprot id: A0A0A2SLT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

198467:AFK25 RS01250
gene id: 198467:AFK25_RS01250
uniprot id: A0A0A2SEB0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

198467:AFK25 RS00690
gene id: 198467:AFK25_RS00690
uniprot id: M5R6M6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

198467:AFK25 RS00960
gene id: 198467:AFK25_RS00960
uniprot id: M5R2S5
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS08015
gene id: 198467:AFK25_RS08015
uniprot id: M5R788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS07930
gene id: 198467:AFK25_RS07930
uniprot id: A0A0A2SEZ7
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS00735
gene id: 198467:AFK25_RS00735
uniprot id: M5QW06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

198467:AFK25 RS10095
gene id: 198467:AFK25_RS10095
uniprot id: A0A0A2SKT1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

198467:AFK25 RS10090
gene id: 198467:AFK25_RS10090
uniprot id: M5QT34
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS05845
gene id: 198467:AFK25_RS05845
uniprot id: A0A0A2SNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

198467:AFK25 RS05385
gene id: 198467:AFK25_RS05385
uniprot id: M5QX61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

198467:AFK25 RS13020
gene id: 198467:AFK25_RS13020
uniprot id: M5QTN6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

198467:AFK25 RS04600
gene id: 198467:AFK25_RS04600
uniprot id: A0A0A2T3I5
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

198467:AFK25 RS11470
gene id: 198467:AFK25_RS11470
uniprot id: A0A0A2SNX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS13980
gene id: 198467:AFK25_RS13980
uniprot id: A0A0A2T2W3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

198467:AFK25 RS01885
gene id: 198467:AFK25_RS01885
uniprot id: A0A7U4NME3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

198467:AFK25 RS04995
gene id: 198467:AFK25_RS04995
uniprot id: A0A0A2T1L9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

198467:AFK25 RS11285
gene id: 198467:AFK25_RS11285
uniprot id: M5R9K4
names: Similarity
messages: Belongs to the thioredoxin family.

198467:AFK25 RS08345
gene id: 198467:AFK25_RS08345
uniprot id: A0A0A2SFS7
names: Similarity
messages: Belongs to the DNA photolyase family.

198467:AFK25 RS11925
gene id: 198467:AFK25_RS11925
uniprot id: A0A0A2SNR0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

198467:AFK25 RS11395
gene id: 198467:AFK25_RS11395
uniprot id: A0A0A2SNZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS07125
gene id: 198467:AFK25_RS07125
uniprot id: M5QW68
names: Similarity
messages: Belongs to the HupF/HypC family.

198467:AFK25 RS11005
gene id: 198467:AFK25_RS11005
uniprot id: A0A0A2SJ86
names: Similarity
messages: Belongs to the GSP E family.

198467:AFK25 RS09590
gene id: 198467:AFK25_RS09590
uniprot id: A0A0A2SY49
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

198467:AFK25 RS05935
gene id: 198467:AFK25_RS05935
uniprot id: M5QQ52
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

198467:AFK25 RS03510
gene id: 198467:AFK25_RS03510
uniprot id: A0A0A2SQ57
names: Similarity
messages: Belongs to the transglycosylase Slt family.

198467:AFK25 RS06275
gene id: 198467:AFK25_RS06275
uniprot id: A0A0A2SJ73
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

198467:AFK25 RS10690
gene id: 198467:AFK25_RS10690
uniprot id: A0A0A2SXI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS02760
gene id: 198467:AFK25_RS02760
uniprot id: A0A0A2T214
names: Similarity
messages: Belongs to the UPF0754 family.

198467:AFK25 RS12490
gene id: 198467:AFK25_RS12490
uniprot id: M5QRV5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

198467:AFK25 RS03530
gene id: 198467:AFK25_RS03530
uniprot id: A0A0A2T2C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS04495
gene id: 198467:AFK25_RS04495
uniprot id: M5QR65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

198467:AFK25 RS10235
gene id: 198467:AFK25_RS10235
uniprot id: A0A0A2SGV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

198467:AFK25 RS12795
gene id: 198467:AFK25_RS12795
uniprot id: M5QS13
names: Cofactor
messages: Binds 1 FAD per subunit.

198467:AFK25 RS03415
gene id: 198467:AFK25_RS03415
uniprot id: A0A0A2SQB5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

198467:AFK25 RS13285
gene id: 198467:AFK25_RS13285
uniprot id: A0A0A2SIP7
names: Similarity
messages: Belongs to the IMPACT family.

198467:AFK25 RS14225
gene id: 198467:AFK25_RS14225
uniprot id: A0A0A2SKL3
names: Similarity
messages: Belongs to the CdaR family.

198467:AFK25 RS11605
gene id: 198467:AFK25_RS11605
uniprot id: A0A0A2SNV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

198467:AFK25 RS10785
gene id: 198467:AFK25_RS10785
uniprot id: M5QUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS06820
gene id: 198467:AFK25_RS06820
uniprot id: A0A0A2SLI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

198467:AFK25 RS00685
gene id: 198467:AFK25_RS00685
uniprot id: M5QVZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

198467:AFK25 RS12595
gene id: 198467:AFK25_RS12595
uniprot id: M5QR68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

198467:AFK25 RS05300
gene id: 198467:AFK25_RS05300
uniprot id: M5QWM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

198467:AFK25 RS05990
gene id: 198467:AFK25_RS05990
uniprot id: A0A0A2SI30
names: Similarity
messages: Belongs to the CdaR family.

198467:AFK25 RS07295
gene id: 198467:AFK25_RS07295
uniprot id: A0A0A2SM68
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

198467:AFK25 RS03455
gene id: 198467:AFK25_RS03455
uniprot id: A0A0A2SLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS10345
gene id: 198467:AFK25_RS10345
uniprot id: A0A0A2SGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

198467:AFK25 RS04170
gene id: 198467:AFK25_RS04170
uniprot id: A0A0A2SWX8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

198467:AFK25 RS02725
gene id: 198467:AFK25_RS02725
uniprot id: A0A0A2SP11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS06015
gene id: 198467:AFK25_RS06015
uniprot id: A0A0A2SM92
names: Similarity
messages: Belongs to the CapA family.

198467:AFK25 RS08785
gene id: 198467:AFK25_RS08785
uniprot id: M5QQU4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

198467:AFK25 RS12940
gene id: 198467:AFK25_RS12940
uniprot id: A0A0A2SHN0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

198467:AFK25 RS03175
gene id: 198467:AFK25_RS03175
uniprot id: A0A0A2SP71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS03240
gene id: 198467:AFK25_RS03240
uniprot id: A0A0A2T279
names: Similarity
messages: Belongs to the CobH/CbiC family.

198467:AFK25 RS13895
gene id: 198467:AFK25_RS13895
uniprot id: A0A0A2SKS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

198467:AFK25 RS11450
gene id: 198467:AFK25_RS11450
uniprot id: A0A0A2T155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

198467:AFK25 RS13830
gene id: 198467:AFK25_RS13830
uniprot id: M5QVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

198467:AFK25 RS04450
gene id: 198467:AFK25_RS04450
uniprot id: A0A0A2SLF0
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS04575
gene id: 198467:AFK25_RS04575
uniprot id: M5QWX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS09560
gene id: 198467:AFK25_RS09560
uniprot id: A0A0A2SKZ9
names: Similarity
messages: Belongs to the cytochrome c-552 family.

198467:AFK25 RS00250
gene id: 198467:AFK25_RS00250
uniprot id: A0A0A2SFF1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

198467:AFK25 RS11355
gene id: 198467:AFK25_RS11355
uniprot id: A0A0A2SKB5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

198467:AFK25 RS13860
gene id: 198467:AFK25_RS13860
uniprot id: A0A0A2SM10
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

198467:AFK25 RS01845
gene id: 198467:AFK25_RS01845
uniprot id: A0A0A2SQL8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

198467:AFK25 RS03655
gene id: 198467:AFK25_RS03655
uniprot id: A0A0A2SPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS06595
gene id: 198467:AFK25_RS06595
uniprot id: A0A0A2SKM1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

198467:AFK25 RS01440
gene id: 198467:AFK25_RS01440
uniprot id: M5QUT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

198467:AFK25 RS03410
gene id: 198467:AFK25_RS03410
uniprot id: M5QSD2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

198467:AFK25 RS12995
gene id: 198467:AFK25_RS12995
uniprot id: M5QTN1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

198467:AFK25 RS10840
gene id: 198467:AFK25_RS10840
uniprot id: M5R5K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

198467:AFK25 RS04595
gene id: 198467:AFK25_RS04595
uniprot id: M5R7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS11130
gene id: 198467:AFK25_RS11130
uniprot id: A0A0A2SNB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

198467:AFK25 RS08545
gene id: 198467:AFK25_RS08545
uniprot id: A0A7U4SK61
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

198467:AFK25 RS00070
gene id: 198467:AFK25_RS00070
uniprot id: A0A0A2SPL3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

198467:AFK25 RS05160
gene id: 198467:AFK25_RS05160
uniprot id: A0A0A2SMQ7
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

198467:AFK25 RS06525
gene id: 198467:AFK25_RS06525
uniprot id: A0A0A2SIK3
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS10150
gene id: 198467:AFK25_RS10150
uniprot id: A0A0A2SXV5
names: Subcellular Location Annotation
messages: Cell membrane

198467:AFK25 RS13085
gene id: 198467:AFK25_RS13085
uniprot id: M5R813
names: PTM
messages: Binds 1 heme c group covalently per subunit.

198467:AFK25 RS10100
gene id: 198467:AFK25_RS10100
uniprot id: M5QQU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

198467:AFK25 RS03375
gene id: 198467:AFK25_RS03375
uniprot id: A0A0A2SQ40
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS01895
gene id: 198467:AFK25_RS01895
uniprot id: A0A0A2SLL3
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspK family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

198467:AFK25 RS08945
gene id: 198467:AFK25_RS08945
uniprot id: M5R314
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

198467:AFK25 RS07435
gene id: 198467:AFK25_RS07435
uniprot id: M5RAR0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

198467:AFK25 RS08460
gene id: 198467:AFK25_RS08460
uniprot id: A0A0A2SJL0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

198467:AFK25 RS12175
gene id: 198467:AFK25_RS12175
uniprot id: A0A0A2SMS9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

198467:AFK25 RS05235
gene id: 198467:AFK25_RS05235
uniprot id: A0A0A2SJS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

198467:AFK25 RS05890
gene id: 198467:AFK25_RS05890
uniprot id: A0A0A2SI46
names: Similarity
messages: Belongs to the ribF family.

198467:AFK25 RS00725
gene id: 198467:AFK25_RS00725
uniprot id: M5RAD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

198467:AFK25 RS08060
gene id: 198467:AFK25_RS08060
uniprot id: A0A0A2SF24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

198467:AFK25 RS09735
gene id: 198467:AFK25_RS09735
uniprot id: M5R774
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

198467:AFK25 RS07635
gene id: 198467:AFK25_RS07635
uniprot id: M5RAV1
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tlp family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

198467:AFK25 RS00405
gene id: 198467:AFK25_RS00405
uniprot id: A0A0A2SJ82
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

198467:AFK25 RS01850
gene id: 198467:AFK25_RS01850
uniprot id: A0A0A2SMN7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

198467:AFK25 RS06795
gene id: 198467:AFK25_RS06795
uniprot id: A0A0A2SHE0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

198467:AFK25 RS00590
gene id: 198467:AFK25_RS00590
uniprot id: A0A0A2SYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

198467:AFK25 RS08350
gene id: 198467:AFK25_RS08350
uniprot id: A0A0A2SWR0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS06340
gene id: 198467:AFK25_RS06340
uniprot id: M5QXH8
names: Similarity
messages: Belongs to the UPF0145 family.

198467:AFK25 RS09900
gene id: 198467:AFK25_RS09900
uniprot id: M5QQQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

198467:AFK25 RS11295
gene id: 198467:AFK25_RS11295
uniprot id: M5QV58
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

198467:AFK25 RS08645
gene id: 198467:AFK25_RS08645
uniprot id: A0A0A2SGF8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

198467:AFK25 RS11910
gene id: 198467:AFK25_RS11910
uniprot id: M5QVH3
names: Similarity
messages: Belongs to the UPF0354 family.

198467:AFK25 RS12660
gene id: 198467:AFK25_RS12660
uniprot id: A0A0A2SJ37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

198467:AFK25 RS01320
gene id: 198467:AFK25_RS01320
uniprot id: M5R8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

198467:AFK25 RS12450
gene id: 198467:AFK25_RS12450
uniprot id: M5R3Y3
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

198467:AFK25 RS13475
gene id: 198467:AFK25_RS13475
uniprot id: A0A0A2SIX1
names: Similarity
messages: Belongs to the peptidase C40 family.

198467:AFK25 RS08020
gene id: 198467:AFK25_RS08020
uniprot id: A0A0A2SGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS07165
gene id: 198467:AFK25_RS07165
uniprot id: A0A0A2SZC0
names: Similarity
messages: Belongs to the SCO1/2 family.

198467:AFK25 RS05745
gene id: 198467:AFK25_RS05745
uniprot id: A0A0A2T0G3
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

198467:AFK25 RS10620
gene id: 198467:AFK25_RS10620
uniprot id: M5R5G4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

198467:AFK25 RS05520
gene id: 198467:AFK25_RS05520
uniprot id: A0A0A2SMK9
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

198467:AFK25 RS13905
gene id: 198467:AFK25_RS13905
uniprot id: A0A0A2T2X9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

198467:AFK25 RS07475
gene id: 198467:AFK25_RS07475
uniprot id: A0A0A2SZ77
names: Similarity
messages: Belongs to the glutamine synthetase family.

198467:AFK25 RS08480
gene id: 198467:AFK25_RS08480
uniprot id: A0A0A2SGI6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS08745
gene id: 198467:AFK25_RS08745
uniprot id: A0A0A2SGD6
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

198467:AFK25 RS07130
gene id: 198467:AFK25_RS07130
uniprot id: A0A0A2SH86
names: Similarity
messages: Belongs to the HypD family.

198467:AFK25 RS09825
gene id: 198467:AFK25_RS09825
uniprot id: M5QQP3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

198467:AFK25 RS02905
gene id: 198467:AFK25_RS02905
uniprot id: A0A0A2SPY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

198467:AFK25 RS05660
gene id: 198467:AFK25_RS05660
uniprot id: A0A0A2SIC5
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS01345
gene id: 198467:AFK25_RS01345
uniprot id: A0A0A2SQX4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

198467:AFK25 RS07225
gene id: 198467:AFK25_RS07225
uniprot id: M5QW90
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

198467:AFK25 RS03435
gene id: 198467:AFK25_RS03435
uniprot id: A0A0A2T2B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS07265
gene id: 198467:AFK25_RS07265
uniprot id: A0A0A2SM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS10770
gene id: 198467:AFK25_RS10770
uniprot id: M5QSP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

198467:AFK25 RS13005
gene id: 198467:AFK25_RS13005
uniprot id: A0A0A2SIU6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PpaX family.
messages: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.

198467:AFK25 RS04430
gene id: 198467:AFK25_RS04430
uniprot id: A0A0A2SME9
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS00990
gene id: 198467:AFK25_RS00990
uniprot id: A0A0A2SEG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

198467:AFK25 RS07285
gene id: 198467:AFK25_RS07285
uniprot id: A0A0A2SL96
names: Similarity
messages: Belongs to the type IA topoisomerase family.

198467:AFK25 RS06000
gene id: 198467:AFK25_RS06000
uniprot id: M5QPH2
names: Cofactor
messages: Binds 1 FAD per subunit.

198467:AFK25 RS04385
gene id: 198467:AFK25_RS04385
uniprot id: A0A0A2SQE0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. MtnX family.
messages: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

198467:AFK25 RS09185
gene id: 198467:AFK25_RS09185
uniprot id: A0A0A2SL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

198467:AFK25 RS09520
gene id: 198467:AFK25_RS09520
uniprot id: A0A0A2SH89
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

198467:AFK25 RS14155
gene id: 198467:AFK25_RS14155
uniprot id: M5RBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

198467:AFK25 RS00660
gene id: 198467:AFK25_RS00660
uniprot id: M5QVZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

198467:AFK25 RS01335
gene id: 198467:AFK25_RS01335
uniprot id: A0A0A2T3X4
names: Similarity
messages: Belongs to the GARS family.

198467:AFK25 RS10865
gene id: 198467:AFK25_RS10865
uniprot id: A0A0A2T1G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

198467:AFK25 RS11750
gene id: 198467:AFK25_RS11750
uniprot id: A0A0A2SIW0
names: Similarity
messages: Belongs to the leucine-binding protein family.

198467:AFK25 RS06160
gene id: 198467:AFK25_RS06160
uniprot id: A0A0A2SJ95
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

198467:AFK25 RS08530
gene id: 198467:AFK25_RS08530
uniprot id: A0A0A2SHR6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS04265
gene id: 198467:AFK25_RS04265
uniprot id: A0A0A2T3H2
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

198467:AFK25 RS10950
gene id: 198467:AFK25_RS10950
uniprot id: A0A0A2SNE6
names: Similarity
messages: Belongs to the UPF0758 family.

198467:AFK25 RS10520
gene id: 198467:AFK25_RS10520
uniprot id: M5QTB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

198467:AFK25 RS00275
gene id: 198467:AFK25_RS00275
uniprot id: M5QW87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

198467:AFK25 RS12845
gene id: 198467:AFK25_RS12845
uniprot id: A0A0A2SZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

198467:AFK25 RS14370
gene id: 198467:AFK25_RS14370
uniprot id: M5RBQ9
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

198467:AFK25 RS03245
gene id: 198467:AFK25_RS03245
uniprot id: A0A0A2SQ24
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

198467:AFK25 RS10595
gene id: 198467:AFK25_RS10595
uniprot id: M5R5F9
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

198467:AFK25 RS12290
gene id: 198467:AFK25_RS12290
uniprot id: A0A0A2SRL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

198467:AFK25 RS14255
gene id: 198467:AFK25_RS14255
uniprot id: A0A0A2SQH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

198467:AFK25 RS05220
gene id: 198467:AFK25_RS05220
uniprot id: A0A0A2SIL5
names: Similarity
messages: Belongs to the UPF0749 family.

198467:AFK25 RS01365
gene id: 198467:AFK25_RS01365
uniprot id: A0A0A2SQY8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

198467:AFK25 RS01460
gene id: 198467:AFK25_RS01460
uniprot id: A0A0A2SRM1
names: Similarity
messages: Belongs to the PspA/IM30 family.

198467:AFK25 RS01400
gene id: 198467:AFK25_RS01400
uniprot id: M5QWQ2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

198467:AFK25 RS05465
gene id: 198467:AFK25_RS05465
uniprot id: A0A0A2SJP3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

198467:AFK25 RS05505
gene id: 198467:AFK25_RS05505
uniprot id: M5RD05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

198467:AFK25 RS05620
gene id: 198467:AFK25_RS05620
uniprot id: A0A0A2T0K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

198467:AFK25 RS11585
gene id: 198467:AFK25_RS11585
uniprot id: A0A0A2T135
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

198467:AFK25 RS13735
gene id: 198467:AFK25_RS13735
uniprot id: A0A0A2SKW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS03585
gene id: 198467:AFK25_RS03585
uniprot id: A0A0A2SLF6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

198467:AFK25 RS07580
gene id: 198467:AFK25_RS07580
uniprot id: M5QWE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

198467:AFK25 RS04640
gene id: 198467:AFK25_RS04640
uniprot id: A0A0A2SQ80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

198467:AFK25 RS11530
gene id: 198467:AFK25_RS11530
uniprot id: M5R5W4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

198467:AFK25 RS09415
gene id: 198467:AFK25_RS09415
uniprot id: M5QR75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

198467:AFK25 RS05475
gene id: 198467:AFK25_RS05475
uniprot id: A0A0A2SIG1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

198467:AFK25 RS01875
gene id: 198467:AFK25_RS01875
uniprot id: A0A0A2SMP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

198467:AFK25 RS13110
gene id: 198467:AFK25_RS13110
uniprot id: M5QQD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

198467:AFK25 RS11370
gene id: 198467:AFK25_RS11370
uniprot id: A0A0A2SNZ5
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

198467:AFK25 RS05240
gene id: 198467:AFK25_RS05240
uniprot id: M5QYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

198467:AFK25 RS01015
gene id: 198467:AFK25_RS01015
uniprot id: A0A0A2SEG8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

198467:AFK25 RS12925
gene id: 198467:AFK25_RS12925
uniprot id: A0A0A2SZS2
names: Similarity
messages: Belongs to the HPr family.

198467:AFK25 RS05340
gene id: 198467:AFK25_RS05340
uniprot id: M5QYE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

198467:AFK25 RS07625
gene id: 198467:AFK25_RS07625
uniprot id: A0A0A2SL52
names: Similarity
messages: Belongs to the HesB/IscA family.

198467:AFK25 RS12980
gene id: 198467:AFK25_RS12980
uniprot id: A0A0A2SIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

198467:AFK25 RS11825
gene id: 198467:AFK25_RS11825
uniprot id: M5R9U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS01725
gene id: 198467:AFK25_RS01725
uniprot id: A0A0A2SQK3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

198467:AFK25 RS01445
gene id: 198467:AFK25_RS01445
uniprot id: M5QTB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS06225
gene id: 198467:AFK25_RS06225
uniprot id: A0A0A2SNN0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

198467:AFK25 RS00715
gene id: 198467:AFK25_RS00715
uniprot id: M5R6N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

198467:AFK25 RS01940
gene id: 198467:AFK25_RS01940
uniprot id: M5QXT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS10260
gene id: 198467:AFK25_RS10260
uniprot id: A0A0A2SGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

198467:AFK25 RS11970
gene id: 198467:AFK25_RS11970
uniprot id: A0A0A2SIS6
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS00625
gene id: 198467:AFK25_RS00625
uniprot id: M5RAB8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

198467:AFK25 RS00765
gene id: 198467:AFK25_RS00765
uniprot id: A0A0A2SYT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS01410
gene id: 198467:AFK25_RS01410
uniprot id: A0A0A2SRM7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

198467:AFK25 RS09460
gene id: 198467:AFK25_RS09460
uniprot id: A0A0A2SY73
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS01370
gene id: 198467:AFK25_RS01370
uniprot id: A0A0A2SMY6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

198467:AFK25 RS12435
gene id: 198467:AFK25_RS12435
uniprot id: M5QRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

198467:AFK25 RS01775
gene id: 198467:AFK25_RS01775
uniprot id: A0A0A2T3L4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS06040
gene id: 198467:AFK25_RS06040
uniprot id: A0A0A2SM84
names: Similarity
messages: Belongs to the MQO family.

198467:AFK25 RS10195
gene id: 198467:AFK25_RS10195
uniprot id: M5QT51
names: Similarity
messages: Belongs to the Fur family.

198467:AFK25 RS10005
gene id: 198467:AFK25_RS10005
uniprot id: A0A0A2SGZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

198467:AFK25 RS02555
gene id: 198467:AFK25_RS02555
uniprot id: M5QS57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS01225
gene id: 198467:AFK25_RS01225
uniprot id: M5R258
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

198467:AFK25 RS06860
gene id: 198467:AFK25_RS06860
uniprot id: M5R1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

198467:AFK25 RS10290
gene id: 198467:AFK25_RS10290
uniprot id: A0A0A2SGJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

198467:AFK25 RS13130
gene id: 198467:AFK25_RS13130
uniprot id: A0A0A2SZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

198467:AFK25 RS08660
gene id: 198467:AFK25_RS08660
uniprot id: M5R6L6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

198467:AFK25 RS11485
gene id: 198467:AFK25_RS11485
uniprot id: A0A0A2SN53
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

198467:AFK25 RS01215
gene id: 198467:AFK25_RS01215
uniprot id: A0A0A2SFG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

198467:AFK25 RS12775
gene id: 198467:AFK25_RS12775
uniprot id: M5QS08
names: Similarity
messages: Belongs to the ArsC family.

198467:AFK25 RS05310
gene id: 198467:AFK25_RS05310
uniprot id: A0A0A2SJR6
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

198467:AFK25 RS08930
gene id: 198467:AFK25_RS08930
uniprot id: A0A0A2SYG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.
messages: Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan.

198467:AFK25 RS00365
gene id: 198467:AFK25_RS00365
uniprot id: A0A0A2SIC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

198467:AFK25 RS01925
gene id: 198467:AFK25_RS01925
uniprot id: M5QW39
names: Similarity
messages: Belongs to the ABC transporter superfamily.

198467:AFK25 RS05435
gene id: 198467:AFK25_RS05435
uniprot id: M5QX73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

198467:AFK25 RS00130
gene id: 198467:AFK25_RS00130
uniprot id: M5RCL9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

198467:AFK25 RS11695
gene id: 198467:AFK25_RS11695
uniprot id: A0A0A2SN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

198467:AFK25 RS11955
gene id: 198467:AFK25_RS11955
uniprot id: A0A0A2T0X1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

198467:AFK25 RS11630
gene id: 198467:AFK25_RS11630
uniprot id: M5R9Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

198467:AFK25 RS09650
gene id: 198467:AFK25_RS09650
uniprot id: A0A0A2SH62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
messages: Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes.
messages: Homotetramer.

198467:AFK25 RS13920
gene id: 198467:AFK25_RS13920
uniprot id: M5QVN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

198467:AFK25 RS09755
gene id: 198467:AFK25_RS09755
uniprot id: A0A0A2SH42
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

198467:AFK25 RS11550
gene id: 198467:AFK25_RS11550
uniprot id: A0A0A2SKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

198467:AFK25 RS00770
gene id: 198467:AFK25_RS00770
uniprot id: M5QTV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

198467:AFK25 RS07375
gene id: 198467:AFK25_RS07375
uniprot id: A0A0A2SL83
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

198467:AFK25 RS09580
gene id: 198467:AFK25_RS09580
uniprot id: A0A0A2SFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

198467:AFK25 RS09335
gene id: 198467:AFK25_RS09335
uniprot id: M5QR59
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

198467:AFK25 RS05535
gene id: 198467:AFK25_RS05535
uniprot id: M5QX90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

198467:AFK25 RS09055
gene id: 198467:AFK25_RS09055
uniprot id: M5QR00
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
messages: Homodimer.
messages: The N-terminal domain has binding sites for ComK and probably for unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

198467:AFK25 RS09800
gene id: 198467:AFK25_RS09800
uniprot id: M5QQN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

198467:AFK25 RS00710
gene id: 198467:AFK25_RS00710
uniprot id: M5QVZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS12560
gene id: 198467:AFK25_RS12560
uniprot id: M5QTF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS06965
gene id: 198467:AFK25_RS06965
uniprot id: M5QUP5
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

198467:AFK25 RS12105
gene id: 198467:AFK25_RS12105
uniprot id: A0A0A2T3Q6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

198467:AFK25 RS05320
gene id: 198467:AFK25_RS05320
uniprot id: M5R913
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

198467:AFK25 RS13565
gene id: 198467:AFK25_RS13565
uniprot id: A0A0A2SEP3
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS07750
gene id: 198467:AFK25_RS07750
uniprot id: A0A0A2SL30
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

198467:AFK25 RS11785
gene id: 198467:AFK25_RS11785
uniprot id: A0A0A2SNS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

198467:AFK25 RS03480
gene id: 198467:AFK25_RS03480
uniprot id: A0A0A2SLD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS13320
gene id: 198467:AFK25_RS13320
uniprot id: A0A0A2SHG9
names: Similarity
messages: Belongs to the peptidase S8 family.

198467:AFK25 RS03220
gene id: 198467:AFK25_RS03220
uniprot id: A0A0A2SQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS02900
gene id: 198467:AFK25_RS02900
uniprot id: M5QRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS09170
gene id: 198467:AFK25_RS09170
uniprot id: A0A0A2SHF1
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

198467:AFK25 RS12965
gene id: 198467:AFK25_RS12965
uniprot id: A0A0A2SHM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

198467:AFK25 RS05140
gene id: 198467:AFK25_RS05140
uniprot id: A0A0A2SIQ4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

198467:AFK25 RS10210
gene id: 198467:AFK25_RS10210
uniprot id: A0A0A2SGW1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS13710
gene id: 198467:AFK25_RS13710
uniprot id: A0A0A2SKW8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

198467:AFK25 RS03465
gene id: 198467:AFK25_RS03465
uniprot id: A0A0A2SQ50
names: Similarity
messages: Belongs to the ABC transporter superfamily.

198467:AFK25 RS08815
gene id: 198467:AFK25_RS08815
uniprot id: M5QSE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Component of the menaquinol-cytochrome c reductase complex.
messages: Membrane
messages: The main subunits of the menaquinone:cytochrome c complex are: cytochrome b, the Rieske protein and a cytochrome b/c subunit.

198467:AFK25 RS01235
gene id: 198467:AFK25_RS01235
uniprot id: M5QPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

198467:AFK25 RS07140
gene id: 198467:AFK25_RS07140
uniprot id: A0A0A2SZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS09220
gene id: 198467:AFK25_RS09220
uniprot id: M5QQE5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

198467:AFK25 RS08410
gene id: 198467:AFK25_RS08410
uniprot id: A0A0A2SJK3
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS13570
gene id: 198467:AFK25_RS13570
uniprot id: A0A0A2SJN0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

198467:AFK25 RS00495
gene id: 198467:AFK25_RS00495
uniprot id: A0A0A2SI16
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

198467:AFK25 RS01315
gene id: 198467:AFK25_RS01315
uniprot id: A0A0A2SMZ7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

198467:AFK25 RS13550
gene id: 198467:AFK25_RS13550
uniprot id: A0A0A2SWU9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

198467:AFK25 RS12735
gene id: 198467:AFK25_RS12735
uniprot id: M5R434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS05400
gene id: 198467:AFK25_RS05400
uniprot id: A0A0A2SNJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

198467:AFK25 RS05605
gene id: 198467:AFK25_RS05605
uniprot id: A0A0A2SMJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

198467:AFK25 RS11170
gene id: 198467:AFK25_RS11170
uniprot id: M5R5R0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

198467:AFK25 RS05230
gene id: 198467:AFK25_RS05230
uniprot id: A0A0A2T0Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

198467:AFK25 RS11540
gene id: 198467:AFK25_RS11540
uniprot id: M5R9N6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

198467:AFK25 RS12285
gene id: 198467:AFK25_RS12285
uniprot id: M5QUC7
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

198467:AFK25 RS12165
gene id: 198467:AFK25_RS12165
uniprot id: M5RA30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

198467:AFK25 RS06570
gene id: 198467:AFK25_RS06570
uniprot id: A0A0A2SFK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

198467:AFK25 RS08940
gene id: 198467:AFK25_RS08940
uniprot id: M5QSH3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

198467:AFK25 RS09115
gene id: 198467:AFK25_RS09115
uniprot id: M5R352
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

198467:AFK25 RS00555
gene id: 198467:AFK25_RS00555
uniprot id: M5QUI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

198467:AFK25 RS14240
gene id: 198467:AFK25_RS14240
uniprot id: M5R7V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS00075
gene id: 198467:AFK25_RS00075
uniprot id: A0A7U4NLV5
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

198467:AFK25 RS01815
gene id: 198467:AFK25_RS01815
uniprot id: A0A0A2SLJ9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

198467:AFK25 RS09665
gene id: 198467:AFK25_RS09665
uniprot id: A0A0A2SKY8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS05970
gene id: 198467:AFK25_RS05970
uniprot id: M5R2C5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

198467:AFK25 RS01030
gene id: 198467:AFK25_RS01030
uniprot id: M5R2R4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

198467:AFK25 RS09035
gene id: 198467:AFK25_RS09035
uniprot id: A0A0A2SLA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS08850
gene id: 198467:AFK25_RS08850
uniprot id: A0A0A2SLE5
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

198467:AFK25 RS09160
gene id: 198467:AFK25_RS09160
uniprot id: A0A0A2SL71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

198467:AFK25 RS04840
gene id: 198467:AFK25_RS04840
uniprot id: A0A0A2SKY6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

198467:AFK25 RS12150
gene id: 198467:AFK25_RS12150
uniprot id: M5QUA3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

198467:AFK25 RS13925
gene id: 198467:AFK25_RS13925
uniprot id: A0A0A2SQQ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS06650
gene id: 198467:AFK25_RS06650
uniprot id: A0A0A2T1J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

198467:AFK25 RS08140
gene id: 198467:AFK25_RS08140
uniprot id: A0A0A2SJA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

198467:AFK25 RS07565
gene id: 198467:AFK25_RS07565
uniprot id: A0A0A2SI84
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS10670
gene id: 198467:AFK25_RS10670
uniprot id: A0A0A2SKG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

198467:AFK25 RS10035
gene id: 198467:AFK25_RS10035
uniprot id: A0A7U4SJY2
names: Subcellular Location Annotation
messages: Mitochondrion

198467:AFK25 RS05630
gene id: 198467:AFK25_RS05630
uniprot id: A0A0A2SMJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

198467:AFK25 RS10395
gene id: 198467:AFK25_RS10395
uniprot id: A0A0A2SYQ6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

198467:AFK25 RS06375
gene id: 198467:AFK25_RS06375
uniprot id: A0A0A2SHX2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

198467:AFK25 RS07185
gene id: 198467:AFK25_RS07185
uniprot id: M5QU29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

198467:AFK25 RS05280
gene id: 198467:AFK25_RS05280
uniprot id: A0A0A2T0Q0
names: Similarity
messages: Belongs to the YggT family.

198467:AFK25 RS12025
gene id: 198467:AFK25_RS12025
uniprot id: M5QTF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS00755
gene id: 198467:AFK25_RS00755
uniprot id: A0A0A2SGL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

198467:AFK25 RS13080
gene id: 198467:AFK25_RS13080
uniprot id: M5QRF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

198467:AFK25 RS13205
gene id: 198467:AFK25_RS13205
uniprot id: A0A0A2SIR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

198467:AFK25 RS03295
gene id: 198467:AFK25_RS03295
uniprot id: A0A0A2SQ30
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

198467:AFK25 RS11085
gene id: 198467:AFK25_RS11085
uniprot id: A0A0A2SP59
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

198467:AFK25 RS09015
gene id: 198467:AFK25_RS09015
uniprot id: A0A0A2SHI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

198467:AFK25 RS06545
gene id: 198467:AFK25_RS06545
uniprot id: A0A0A2SFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS03280
gene id: 198467:AFK25_RS03280
uniprot id: A0A0A2SP87
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

198467:AFK25 RS00005
gene id: 198467:AFK25_RS00005
uniprot id: M5QXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

198467:AFK25 RS05735
gene id: 198467:AFK25_RS05735
uniprot id: A0A0A2SI79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

198467:AFK25 RS09685
gene id: 198467:AFK25_RS09685
uniprot id: A0A0A2SFY1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

198467:AFK25 RS11900
gene id: 198467:AFK25_RS11900
uniprot id: M5R9V8
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

198467:AFK25 RS14685
gene id: 198467:AFK25_RS14685
uniprot id: M5R8E9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS09740
gene id: 198467:AFK25_RS09740
uniprot id: M5QRD1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

198467:AFK25 RS13970
gene id: 198467:AFK25_RS13970
uniprot id: A0A0A2SKR1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS08760
gene id: 198467:AFK25_RS08760
uniprot id: A0A0A2SHN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

198467:AFK25 RS09150
gene id: 198467:AFK25_RS09150
uniprot id: A0A0A2SKD1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

198467:AFK25 RS04160
gene id: 198467:AFK25_RS04160
uniprot id: A0A0A2SES9
names: Similarity
messages: Belongs to the asparaginase 1 family.

198467:AFK25 RS01960
gene id: 198467:AFK25_RS01960
uniprot id: A0A0A2SMQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS04420
gene id: 198467:AFK25_RS04420
uniprot id: A0A0A2SR91
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS09475
gene id: 198467:AFK25_RS09475
uniprot id: A0A0A2SG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS04165
gene id: 198467:AFK25_RS04165
uniprot id: A0A0A2SJS9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

198467:AFK25 RS05245
gene id: 198467:AFK25_RS05245
uniprot id: A0A0A2SIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
messages: Self-associates. Interacts with SigE. Interacts with SpoIIR.

198467:AFK25 RS10220
gene id: 198467:AFK25_RS10220
uniprot id: M5QT56
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

198467:AFK25 RS07960
gene id: 198467:AFK25_RS07960
uniprot id: A0A0A2SF03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

198467:AFK25 RS06775
gene id: 198467:AFK25_RS06775
uniprot id: M5R5J9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

198467:AFK25 RS00215
gene id: 198467:AFK25_RS00215
uniprot id: M5QWN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS01935
gene id: 198467:AFK25_RS01935
uniprot id: A0A0A2SMP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS04675
gene id: 198467:AFK25_RS04675
uniprot id: A0A0A2SL19
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS10425
gene id: 198467:AFK25_RS10425
uniprot id: M5R3T6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

198467:AFK25 RS04145
gene id: 198467:AFK25_RS04145
uniprot id: A0A7U4NN93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

198467:AFK25 RS08860
gene id: 198467:AFK25_RS08860
uniprot id: A0A0A2SHL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

198467:AFK25 RS13915
gene id: 198467:AFK25_RS13915
uniprot id: A0A0A2SPX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

198467:AFK25 RS13210
gene id: 198467:AFK25_RS13210
uniprot id: A0A0A2SLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

198467:AFK25 RS07345
gene id: 198467:AFK25_RS07345
uniprot id: A0A0A2SIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS12180
gene id: 198467:AFK25_RS12180
uniprot id: A0A0A2T3S0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

198467:AFK25 RS07410
gene id: 198467:AFK25_RS07410
uniprot id: A0A0A2SH45
names: Similarity
messages: Belongs to the EamA transporter family.

198467:AFK25 RS00545
gene id: 198467:AFK25_RS00545
uniprot id: M5QTR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

198467:AFK25 RS11790
gene id: 198467:AFK25_RS11790
uniprot id: A0A0A2T0Z8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

198467:AFK25 RS09085
gene id: 198467:AFK25_RS09085
uniprot id: M5QSK7
names: Similarity
messages: Belongs to the manganese catalase family.

198467:AFK25 RS05930
gene id: 198467:AFK25_RS05930
uniprot id: M5R5Z0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS00115
gene id: 198467:AFK25_RS00115
uniprot id: M5R8R4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

198467:AFK25 RS07980
gene id: 198467:AFK25_RS07980
uniprot id: A0A0A2SK39
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

198467:AFK25 RS07330
gene id: 198467:AFK25_RS07330
uniprot id: A0A0A2SZ97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS03745
gene id: 198467:AFK25_RS03745
uniprot id: A0A0A2T2G3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

198467:AFK25 RS06960
gene id: 198467:AFK25_RS06960
uniprot id: A0A0A2SHF5
names: Similarity
messages: Belongs to the UPF0047 family.

198467:AFK25 RS11795
gene id: 198467:AFK25_RS11795
uniprot id: M5QT94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

198467:AFK25 RS03730
gene id: 198467:AFK25_RS03730
uniprot id: A0A0A2SKD0
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

198467:AFK25 RS01740
gene id: 198467:AFK25_RS01740
uniprot id: M5QWD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

198467:AFK25 RS02680
gene id: 198467:AFK25_RS02680
uniprot id: A0A0A2SL18
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS08865
gene id: 198467:AFK25_RS08865
uniprot id: A0A0A2SKI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

198467:AFK25 RS01995
gene id: 198467:AFK25_RS01995
uniprot id: M5R8G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0295 family.
messages: Cell membrane

198467:AFK25 RS06625
gene id: 198467:AFK25_RS06625
uniprot id: A0A0A2T1J5
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.
messages: Belongs to the eukaryotic diacylglycerol kinase family.

198467:AFK25 RS04415
gene id: 198467:AFK25_RS04415
uniprot id: A0A0A2SLB0
names: Similarity
messages: Belongs to the PemK/MazF family.

198467:AFK25 RS10615
gene id: 198467:AFK25_RS10615
uniprot id: A0A0A2SKF0
names: Similarity
messages: Belongs to the transpeptidase family.

198467:AFK25 RS09350
gene id: 198467:AFK25_RS09350
uniprot id: M5QQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS05295
gene id: 198467:AFK25_RS05295
uniprot id: M5R8Z6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

198467:AFK25 RS00380
gene id: 198467:AFK25_RS00380
uniprot id: M5RCE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS01430
gene id: 198467:AFK25_RS01430
uniprot id: A0A0A2SLT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS09530
gene id: 198467:AFK25_RS09530
uniprot id: A0A0A2SG05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

198467:AFK25 RS02495
gene id: 198467:AFK25_RS02495
uniprot id: A0A0A2SJP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

198467:AFK25 RS05895
gene id: 198467:AFK25_RS05895
uniprot id: M5QX77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

198467:AFK25 RS14580
gene id: 198467:AFK25_RS14580
uniprot id: A0A0A2SGG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

198467:AFK25 RS00640
gene id: 198467:AFK25_RS00640
uniprot id: M5R6L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

198467:AFK25 RS00955
gene id: 198467:AFK25_RS00955
uniprot id: A0A0A2SJF5
names: Subcellular Location Annotation
messages: Cell membrane

198467:AFK25 RS00370
gene id: 198467:AFK25_RS00370
uniprot id: M5QXV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

198467:AFK25 RS09785
gene id: 198467:AFK25_RS09785
uniprot id: A0A0A2SK19
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

198467:AFK25 RS10190
gene id: 198467:AFK25_RS10190
uniprot id: M5QRK8
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

198467:AFK25 RS05555
gene id: 198467:AFK25_RS05555
uniprot id: M5RD15
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

198467:AFK25 RS01880
gene id: 198467:AFK25_RS01880
uniprot id: A0A0A2T3N1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

198467:AFK25 RS06325
gene id: 198467:AFK25_RS06325
uniprot id: M5QVU1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

198467:AFK25 RS00885
gene id: 198467:AFK25_RS00885
uniprot id: M5R265
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

198467:AFK25 RS05545
gene id: 198467:AFK25_RS05545
uniprot id: A0A0A2SMK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

198467:AFK25 RS13760
gene id: 198467:AFK25_RS13760
uniprot id: A0A0A2SKV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

198467:AFK25 RS12710
gene id: 198467:AFK25_RS12710
uniprot id: M5R429
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

198467:AFK25 RS01200
gene id: 198467:AFK25_RS01200
uniprot id: M5R254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

198467:AFK25 RS14405
gene id: 198467:AFK25_RS14405
uniprot id: A0A0A2SLQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

198467:AFK25 RS12265
gene id: 198467:AFK25_RS12265
uniprot id: M5QVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

198467:AFK25 RS14270
gene id: 198467:AFK25_RS14270
uniprot id: A0A0A2SLT5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

198467:AFK25 RS09995
gene id: 198467:AFK25_RS09995
uniprot id: A0A0A2SKU3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

198467:AFK25 RS01930
gene id: 198467:AFK25_RS01930
uniprot id: A0A0A2SQN1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

198467:AFK25 RS03365
gene id: 198467:AFK25_RS03365
uniprot id: A0A0A2SLB5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

198467:AFK25 RS13585
gene id: 198467:AFK25_RS13585
uniprot id: A0A0A2SIV3
names: Similarity
messages: Belongs to the CvfB family.

198467:AFK25 RS10795
gene id: 198467:AFK25_RS10795
uniprot id: A0A0A2SXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

198467:AFK25 RS11095
gene id: 198467:AFK25_RS11095
uniprot id: A0A0A2SKG0
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS08335
gene id: 198467:AFK25_RS08335
uniprot id: M5RB89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS09205
gene id: 198467:AFK25_RS09205
uniprot id: M5QR37
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS09830
gene id: 198467:AFK25_RS09830
uniprot id: A0A0A2SH26
names: Similarity
messages: Belongs to the asp23 family.

198467:AFK25 RS03000
gene id: 198467:AFK25_RS03000
uniprot id: A0A0A2SL62
names: Cofactor
messages: Can also use Mn(2+) ion.

198467:AFK25 RS08200
gene id: 198467:AFK25_RS08200
uniprot id: A0A7U4SK71
names: Similarity
messages: Belongs to the UPF0236 family.

198467:AFK25 RS05195
gene id: 198467:AFK25_RS05195
uniprot id: M5R8X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

198467:AFK25 RS07000
gene id: 198467:AFK25_RS07000
uniprot id: A0A0A2SLE9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

198467:AFK25 RS10295
gene id: 198467:AFK25_RS10295
uniprot id: A0A0A2SJT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

198467:AFK25 RS14725
gene id: 198467:AFK25_RS14725
uniprot id: M5QRQ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS02825
gene id: 198467:AFK25_RS02825
uniprot id: A0A0A2SPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

198467:AFK25 RS07245
gene id: 198467:AFK25_RS07245
uniprot id: A0A0A2SZB0
names: Function
names: Subunit
messages: Homodimer.
messages: Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat.

198467:AFK25 RS05015
gene id: 198467:AFK25_RS05015
uniprot id: M5RCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

198467:AFK25 RS00425
gene id: 198467:AFK25_RS00425
uniprot id: M5QWJ2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

198467:AFK25 RS12280
gene id: 198467:AFK25_RS12280
uniprot id: A0A0A2SMU9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

198467:AFK25 RS11000
gene id: 198467:AFK25_RS11000
uniprot id: A0A0A2SND7
names: Similarity
messages: Belongs to the GSP E family.

198467:AFK25 RS04075
gene id: 198467:AFK25_RS04075
uniprot id: A0A0A2SG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS14610
gene id: 198467:AFK25_RS14610
uniprot id: A0A0A2SGG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

198467:AFK25 RS02675
gene id: 198467:AFK25_RS02675
uniprot id: A0A0A2SP03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS07425
gene id: 198467:AFK25_RS07425
uniprot id: A0A0A2SIA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

198467:AFK25 RS07820
gene id: 198467:AFK25_RS07820
uniprot id: A0A0A2SJZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

198467:AFK25 RS05835
gene id: 198467:AFK25_RS05835
uniprot id: A0A0A2SMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

198467:AFK25 RS05805
gene id: 198467:AFK25_RS05805
uniprot id: M5QXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

198467:AFK25 RS14635
gene id: 198467:AFK25_RS14635
uniprot id: A0A0A2SGH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

198467:AFK25 RS14490
gene id: 198467:AFK25_RS14490
uniprot id: A0A0A2SJC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS14815
gene id: 198467:AFK25_RS14815
uniprot id: M5QWF9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS02610
gene id: 198467:AFK25_RS02610
uniprot id: M5R4Z4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

198467:AFK25 RS12190
gene id: 198467:AFK25_RS12190
uniprot id: A0A0A2SRJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

198467:AFK25 RS04405
gene id: 198467:AFK25_RS04405
uniprot id: A0A0A2SMF1
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS01570
gene id: 198467:AFK25_RS01570
uniprot id: A0A0A2SMJ2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

198467:AFK25 RS11420
gene id: 198467:AFK25_RS11420
uniprot id: A0A7U4SKP2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

198467:AFK25 RS13295
gene id: 198467:AFK25_RS13295
uniprot id: A0A0A2SHH3
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS11600
gene id: 198467:AFK25_RS11600
uniprot id: M5QV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

198467:AFK25 RS09675
gene id: 198467:AFK25_RS09675
uniprot id: A0A0A2SH57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

198467:AFK25 RS14230
gene id: 198467:AFK25_RS14230
uniprot id: M5QVU4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

198467:AFK25 RS10750
gene id: 198467:AFK25_RS10750
uniprot id: A0A0A2SKI0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

198467:AFK25 RS09330
gene id: 198467:AFK25_RS09330
uniprot id: A0A0A2SY95
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

198467:AFK25 RS05135
gene id: 198467:AFK25_RS05135
uniprot id: A0A0A2SIM9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

198467:AFK25 RS12470
gene id: 198467:AFK25_RS12470
uniprot id: A0A0A2SEV6
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

198467:AFK25 RS10650
gene id: 198467:AFK25_RS10650
uniprot id: A0A0A2SJI0
names: Similarity
messages: Belongs to the UPF0473 family.

198467:AFK25 RS12720
gene id: 198467:AFK25_RS12720
uniprot id: M5R7U7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

198467:AFK25 RS06895
gene id: 198467:AFK25_RS06895
uniprot id: M5QW24
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspP family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

198467:AFK25 RS13940
gene id: 198467:AFK25_RS13940
uniprot id: M5RBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

198467:AFK25 RS07030
gene id: 198467:AFK25_RS07030
uniprot id: M5RAI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

198467:AFK25 RS12010
gene id: 198467:AFK25_RS12010
uniprot id: A0A0A2SJY6
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS05700
gene id: 198467:AFK25_RS05700
uniprot id: A0A0A2SJL2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

198467:AFK25 RS13335
gene id: 198467:AFK25_RS13335
uniprot id: A0A0A2SIN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

198467:AFK25 RS10625
gene id: 198467:AFK25_RS10625
uniprot id: M5QSM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

198467:AFK25 RS04360
gene id: 198467:AFK25_RS04360
uniprot id: M5R656
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Homodimer.

198467:AFK25 RS00460
gene id: 198467:AFK25_RS00460
uniprot id: M5QVS2
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.

198467:AFK25 RS01390
gene id: 198467:AFK25_RS01390
uniprot id: A0A0A2T3W5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

198467:AFK25 RS09255
gene id: 198467:AFK25_RS09255
uniprot id: A0A0A2SG47
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

198467:AFK25 RS05885
gene id: 198467:AFK25_RS05885
uniprot id: A0A0A2SMC1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

198467:AFK25 RS01475
gene id: 198467:AFK25_RS01475
uniprot id: A0A0A2SQV0
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS14615
gene id: 198467:AFK25_RS14615
uniprot id: A0A0A2SXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

198467:AFK25 RS05305
gene id: 198467:AFK25_RS05305
uniprot id: A0A0A2T0P6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

198467:AFK25 RS00670
gene id: 198467:AFK25_RS00670
uniprot id: M5QTT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

198467:AFK25 RS01530
gene id: 198467:AFK25_RS01530
uniprot id: A0A7U4SIY8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

198467:AFK25 RS06825
gene id: 198467:AFK25_RS06825
uniprot id: A0A0A2SHD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

198467:AFK25 RS09840
gene id: 198467:AFK25_RS09840
uniprot id: A0A0A2SFV5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

198467:AFK25 RS03475
gene id: 198467:AFK25_RS03475
uniprot id: M5QRK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

198467:AFK25 RS08765
gene id: 198467:AFK25_RS08765
uniprot id: A0A0A2SKJ8
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS00630
gene id: 198467:AFK25_RS00630
uniprot id: M5QUJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

198467:AFK25 RS10375
gene id: 198467:AFK25_RS10375
uniprot id: A0A0A2SJS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

198467:AFK25 RS13780
gene id: 198467:AFK25_RS13780
uniprot id: A0A0A2SM56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

198467:AFK25 RS04735
gene id: 198467:AFK25_RS04735
uniprot id: A0A0A2SL06
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

198467:AFK25 RS10485
gene id: 198467:AFK25_RS10485
uniprot id: A0A0A2SJQ8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

198467:AFK25 RS03450
gene id: 198467:AFK25_RS03450
uniprot id: A0A0A2SPB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS10800
gene id: 198467:AFK25_RS10800
uniprot id: M5R9A3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

198467:AFK25 RS00110
gene id: 198467:AFK25_RS00110
uniprot id: M5QWE9
names: Similarity
messages: Belongs to the DCK/DGK family.

198467:AFK25 RS05560
gene id: 198467:AFK25_RS05560
uniprot id: M5QX93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS04090
gene id: 198467:AFK25_RS04090
uniprot id: A0A0A2SJU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

198467:AFK25 RS01295
gene id: 198467:AFK25_RS01295
uniprot id: M5R8Q3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

198467:AFK25 RS02645
gene id: 198467:AFK25_RS02645
uniprot id: A0A0A2SJV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS09545
gene id: 198467:AFK25_RS09545
uniprot id: A0A0A2SH84
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

198467:AFK25 RS01645
gene id: 198467:AFK25_RS01645
uniprot id: A0A0A2SLH0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

198467:AFK25 RS11430
gene id: 198467:AFK25_RS11430
uniprot id: A0A0A2SKA1
names: Similarity
messages: Belongs to the aldose epimerase family.

198467:AFK25 RS12170
gene id: 198467:AFK25_RS12170
uniprot id: M5QUA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

198467:AFK25 RS02870
gene id: 198467:AFK25_RS02870
uniprot id: A0A0A2T226
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

198467:AFK25 RS11165
gene id: 198467:AFK25_RS11165
uniprot id: A0A0A2T1I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

198467:AFK25 RS10945
gene id: 198467:AFK25_RS10945
uniprot id: M5R5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

198467:AFK25 RS07005
gene id: 198467:AFK25_RS07005
uniprot id: A0A0A2SHA8
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS01665
gene id: 198467:AFK25_RS01665
uniprot id: M5QXM8
names: Similarity
messages: Belongs to the peptidase C40 family.

198467:AFK25 RS00945
gene id: 198467:AFK25_RS00945
uniprot id: A0A0A2SFL7
names: Similarity
messages: Belongs to the PspA/IM30 family.

198467:AFK25 RS09555
gene id: 198467:AFK25_RS09555
uniprot id: A0A0A2SG00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS11805
gene id: 198467:AFK25_RS11805
uniprot id: A0A0A2SIV2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

198467:AFK25 RS12900
gene id: 198467:AFK25_RS12900
uniprot id: M5QRB4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

198467:AFK25 RS12890
gene id: 198467:AFK25_RS12890
uniprot id: A0A0A2SMN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS08965
gene id: 198467:AFK25_RS08965
uniprot id: A0A0A2SHJ3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

198467:AFK25 RS14115
gene id: 198467:AFK25_RS14115
uniprot id: M5R7T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

198467:AFK25 RS10365
gene id: 198467:AFK25_RS10365
uniprot id: M5QRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

198467:AFK25 RS07990
gene id: 198467:AFK25_RS07990
uniprot id: A0A0A2SJ74
names: Similarity
messages: Belongs to the TelA family.

198467:AFK25 RS00570
gene id: 198467:AFK25_RS00570
uniprot id: A0A0A2SI03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

198467:AFK25 RS01290
gene id: 198467:AFK25_RS01290
uniprot id: M5QWD9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

198467:AFK25 RS11400
gene id: 198467:AFK25_RS11400
uniprot id: A0A0A2T163
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS09390
gene id: 198467:AFK25_RS09390
uniprot id: M5QR69
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

198467:AFK25 RS10680
gene id: 198467:AFK25_RS10680
uniprot id: A0A0A2SJI6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

198467:AFK25 RS03360
gene id: 198467:AFK25_RS03360
uniprot id: A0A7U4NMY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

198467:AFK25 RS14555
gene id: 198467:AFK25_RS14555
uniprot id: M5RBU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

198467:AFK25 RS11150
gene id: 198467:AFK25_RS11150
uniprot id: M5QSX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS03560
gene id: 198467:AFK25_RS03560
uniprot id: A0A7U4SJ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

198467:AFK25 RS14140
gene id: 198467:AFK25_RS14140
uniprot id: A0A0A2SPS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

198467:AFK25 RS01830
gene id: 198467:AFK25_RS01830
uniprot id: A0A0A2T3M3
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

198467:AFK25 RS05365
gene id: 198467:AFK25_RS05365
uniprot id: A0A0A2SMN0
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

198467:AFK25 RS10860
gene id: 198467:AFK25_RS10860
uniprot id: M5QTH5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

198467:AFK25 RS00890
gene id: 198467:AFK25_RS00890
uniprot id: M5QPA4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

198467:AFK25 RS05740
gene id: 198467:AFK25_RS05740
uniprot id: A0A0A2SNC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

198467:AFK25 RS05485
gene id: 198467:AFK25_RS05485
uniprot id: M5QX79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

198467:AFK25 RS14410
gene id: 198467:AFK25_RS14410
uniprot id: M5R7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS05000
gene id: 198467:AFK25_RS05000
uniprot id: A0A0A2SPI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

198467:AFK25 RS01690
gene id: 198467:AFK25_RS01690
uniprot id: A0A0A2SRE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

198467:AFK25 RS08265
gene id: 198467:AFK25_RS08265
uniprot id: A0A0A2SJI8
names: Similarity
messages: Belongs to the TPP enzyme family.

198467:AFK25 RS05635
gene id: 198467:AFK25_RS05635
uniprot id: A0A0A2SID0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

198467:AFK25 RS10655
gene id: 198467:AFK25_RS10655
uniprot id: M5R971
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

198467:AFK25 RS11335
gene id: 198467:AFK25_RS11335
uniprot id: A0A0A2SPD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

198467:AFK25 RS06930
gene id: 198467:AFK25_RS06930
uniprot id: A0A0A2SMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

198467:AFK25 RS13990
gene id: 198467:AFK25_RS13990
uniprot id: A0A0A2SPV7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

198467:AFK25 RS05640
gene id: 198467:AFK25_RS05640
uniprot id: A0A0A2SNG3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

198467:AFK25 RS05500
gene id: 198467:AFK25_RS05500
uniprot id: M5QX06
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

198467:AFK25 RS08695
gene id: 198467:AFK25_RS08695
uniprot id: A0A0A2SGF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

198467:AFK25 RS09990
gene id: 198467:AFK25_RS09990
uniprot id: A0A0A2SFS8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

198467:AFK25 RS02550
gene id: 198467:AFK25_RS02550
uniprot id: M5R8Q2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

198467:AFK25 RS00740
gene id: 198467:AFK25_RS00740
uniprot id: M5R6N4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

198467:AFK25 RS03100
gene id: 198467:AFK25_RS03100
uniprot id: A0A0A2SP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

198467:AFK25 RS13485
gene id: 198467:AFK25_RS13485
uniprot id: A0A0A2SJP9
names: Similarity
messages: Belongs to the peptidase S8 family.

198467:AFK25 RS01105
gene id: 198467:AFK25_RS01105
uniprot id: M5R2Q1
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

198467:AFK25 RS04325
gene id: 198467:AFK25_RS04325
uniprot id: M5R2G9
names: Function
names: Similarity
messages: Belongs to the LutB/YkgF family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate.

198467:AFK25 RS00655
gene id: 198467:AFK25_RS00655
uniprot id: M5QUK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

198467:AFK25 RS01480
gene id: 198467:AFK25_RS01480
uniprot id: A0A0A2SLS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

198467:AFK25 RS14085
gene id: 198467:AFK25_RS14085
uniprot id: A0A0A2SLX1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

198467:AFK25 RS05170
gene id: 198467:AFK25_RS05170
uniprot id: A0A0A2SNL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

198467:AFK25 RS10665
gene id: 198467:AFK25_RS10665
uniprot id: M5QUW5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

198467:AFK25 RS03165
gene id: 198467:AFK25_RS03165
uniprot id: A0A0A2SQ14
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

198467:AFK25 RS05345
gene id: 198467:AFK25_RS05345
uniprot id: M5R927
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

198467:AFK25 RS11075
gene id: 198467:AFK25_RS11075
uniprot id: A0A0A2SNC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS10455
gene id: 198467:AFK25_RS10455
uniprot id: A0A0A2SGT5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

198467:AFK25 RS02620
gene id: 198467:AFK25_RS02620
uniprot id: M5QSV9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

198467:AFK25 RS03710
gene id: 198467:AFK25_RS03710
uniprot id: A0A0A2SPF9
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

198467:AFK25 RS10830
gene id: 198467:AFK25_RS10830
uniprot id: A0A0A2SKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

198467:AFK25 RS12975
gene id: 198467:AFK25_RS12975
uniprot id: A0A0A2SZR2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

198467:AFK25 RS04760
gene id: 198467:AFK25_RS04760
uniprot id: M5QRM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

198467:AFK25 RS04030
gene id: 198467:AFK25_RS04030
uniprot id: A0A0A2SIY4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

198467:AFK25 RS05210
gene id: 198467:AFK25_RS05210
uniprot id: M5QWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

198467:AFK25 RS10545
gene id: 198467:AFK25_RS10545
uniprot id: M5QTC1
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

198467:AFK25 RS01675
gene id: 198467:AFK25_RS01675
uniprot id: A0A0A2SQJ5
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.
messages: Belongs to the sulfur carrier protein TusA family.

198467:AFK25 RS10140
gene id: 198467:AFK25_RS10140
uniprot id: A0A0A2SFQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

198467:AFK25 RS03540
gene id: 198467:AFK25_RS03540
uniprot id: A0A0A2SK98
names: Function
names: Similarity
messages: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP.
messages: Belongs to the PrpE family.

198467:AFK25 RS13235
gene id: 198467:AFK25_RS13235
uniprot id: A0A0A2SLM2
names: Similarity
messages: Belongs to the FlgM family.

198467:AFK25 RS07440
gene id: 198467:AFK25_RS07440
uniprot id: M5QUW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

198467:AFK25 RS14025
gene id: 198467:AFK25_RS14025
uniprot id: M5QX34
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

198467:AFK25 RS05615
gene id: 198467:AFK25_RS05615
uniprot id: M5QYI9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

198467:AFK25 RS01210
gene id: 198467:AFK25_RS01210
uniprot id: A0A0A2SJB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

198467:AFK25 RS05600
gene id: 198467:AFK25_RS05600
uniprot id: A0A0A2SJM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

198467:AFK25 RS06640
gene id: 198467:AFK25_RS06640
uniprot id: M5R228
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS05490
gene id: 198467:AFK25_RS05490
uniprot id: A0A0A2SJN8
names: Similarity
messages: Belongs to the fabD family.

198467:AFK25 RS13135
gene id: 198467:AFK25_RS13135
uniprot id: A0A0A2SIS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

198467:AFK25 RS00645
gene id: 198467:AFK25_RS00645
uniprot id: M5QTT4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

198467:AFK25 RS05355
gene id: 198467:AFK25_RS05355
uniprot id: A0A0A2T0N7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS10130
gene id: 198467:AFK25_RS10130
uniprot id: M5R7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS00490
gene id: 198467:AFK25_RS00490
uniprot id: M5QTQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

198467:AFK25 RS10360
gene id: 198467:AFK25_RS10360
uniprot id: A0A0A2SKP8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

198467:AFK25 RS10370
gene id: 198467:AFK25_RS10370
uniprot id: M5QT84
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

198467:AFK25 RS10695
gene id: 198467:AFK25_RS10695
uniprot id: A0A0A2SKG8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

198467:AFK25 RS13875
gene id: 198467:AFK25_RS13875
uniprot id: A0A0A2SQR6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

198467:AFK25 RS13075
gene id: 198467:AFK25_RS13075
uniprot id: A0A0A2SZP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

198467:AFK25 RS06470
gene id: 198467:AFK25_RS06470
uniprot id: A0A0A2SJ40
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

198467:AFK25 RS09795
gene id: 198467:AFK25_RS09795
uniprot id: M5R3H6
names: Similarity
messages: Belongs to the TlyA family.

198467:AFK25 RS05800
gene id: 198467:AFK25_RS05800
uniprot id: A0A0A2T0E8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

198467:AFK25 RS06510
gene id: 198467:AFK25_RS06510
uniprot id: M5QRH7
names: Subcellular Location Annotation
messages: Cell membrane

198467:AFK25 RS05900
gene id: 198467:AFK25_RS05900
uniprot id: A0A0A2T0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

198467:AFK25 RS13910
gene id: 198467:AFK25_RS13910
uniprot id: M5QVE7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

198467:AFK25 RS08915
gene id: 198467:AFK25_RS08915
uniprot id: M5QSG8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

198467:AFK25 RS08935
gene id: 198467:AFK25_RS08935
uniprot id: A0A0A2SHJ7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

198467:AFK25 RS00095
gene id: 198467:AFK25_RS00095
uniprot id: A0A0A2SPL7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS09435
gene id: 198467:AFK25_RS09435
uniprot id: M5R723
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Component of the MPD complex composed of SpoIIM, SpoIIP and SpoIID.
messages: Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.

198467:AFK25 RS13280
gene id: 198467:AFK25_RS13280
uniprot id: A0A0A2SZL7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

198467:AFK25 RS13825
gene id: 198467:AFK25_RS13825
uniprot id: A0A0A2T2Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

198467:AFK25 RS06050
gene id: 198467:AFK25_RS06050
uniprot id: A0A0A2T0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS09125
gene id: 198467:AFK25_RS09125
uniprot id: A0A0A2SKD5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

198467:AFK25 RS00540
gene id: 198467:AFK25_RS00540
uniprot id: M5R6K0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

198467:AFK25 RS13835
gene id: 198467:AFK25_RS13835
uniprot id: M5RBI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

198467:AFK25 RS05705
gene id: 198467:AFK25_RS05705
uniprot id: A0A0A2SMH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

198467:AFK25 RS04130
gene id: 198467:AFK25_RS04130
uniprot id: A0A0A2SJ00
names: Similarity
messages: Belongs to the PemK/MazF family.

198467:AFK25 RS00255
gene id: 198467:AFK25_RS00255
uniprot id: A0A0A2SID9
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

198467:AFK25 RS00020
gene id: 198467:AFK25_RS00020
uniprot id: A0A0A2SGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

198467:AFK25 RS09660
gene id: 198467:AFK25_RS09660
uniprot id: A0A0A2SFY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

198467:AFK25 RS07115
gene id: 198467:AFK25_RS07115
uniprot id: A0A0A2SZC7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

198467:AFK25 RS01095
gene id: 198467:AFK25_RS01095
uniprot id: M5R6F8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

198467:AFK25 RS05840
gene id: 198467:AFK25_RS05840
uniprot id: M5R9B7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS04025
gene id: 198467:AFK25_RS04025
uniprot id: A0A0A2SG04
names: Similarity
messages: Belongs to the pirin family.

198467:AFK25 RS03095
gene id: 198467:AFK25_RS03095
uniprot id: A0A0A2SK26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

198467:AFK25 RS04320
gene id: 198467:AFK25_RS04320
uniprot id: A0A0A2T3G5
names: Function
names: Similarity
messages: Belongs to the LutA/YkgE family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.

198467:AFK25 RS01115
gene id: 198467:AFK25_RS01115
uniprot id: A0A0A2SWN3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

198467:AFK25 RS12780
gene id: 198467:AFK25_RS12780
uniprot id: A0A0A2SLV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

198467:AFK25 RS03180
gene id: 198467:AFK25_RS03180
uniprot id: A0A0A2SL87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS10660
gene id: 198467:AFK25_RS10660
uniprot id: A0A0A2SKM3
names: Similarity
messages: Belongs to the UPF0297 family.

198467:AFK25 RS10335
gene id: 198467:AFK25_RS10335
uniprot id: M5R7H9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

198467:AFK25 RS05525
gene id: 198467:AFK25_RS05525
uniprot id: A0A0A2SIF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

198467:AFK25 RS09695
gene id: 198467:AFK25_RS09695
uniprot id: A0A0A2SY32
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

198467:AFK25 RS11025
gene id: 198467:AFK25_RS11025
uniprot id: A0A0A2SND3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

198467:AFK25 RS10925
gene id: 198467:AFK25_RS10925
uniprot id: M5QSS4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

198467:AFK25 RS06950
gene id: 198467:AFK25_RS06950
uniprot id: M5R6R2
names: Subcellular Location Annotation
messages: Cytoplasm

198467:AFK25 RS13865
gene id: 198467:AFK25_RS13865
uniprot id: M5RBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS05725
gene id: 198467:AFK25_RS05725
uniprot id: A0A0A2SJJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

198467:AFK25 RS05175
gene id: 198467:AFK25_RS05175
uniprot id: A0A0A2T0R6
names: Similarity
messages: Belongs to the transpeptidase family.

198467:AFK25 RS10815
gene id: 198467:AFK25_RS10815
uniprot id: A0A0A2SJN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

198467:AFK25 RS01285
gene id: 198467:AFK25_RS01285
uniprot id: A0A0A2T3Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

198467:AFK25 RS09805
gene id: 198467:AFK25_RS09805
uniprot id: M5R787
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

198467:AFK25 RS00600
gene id: 198467:AFK25_RS00600
uniprot id: M5RAB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

198467:AFK25 RS12605
gene id: 198467:AFK25_RS12605
uniprot id: A0A0A2T006
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

198467:AFK25 RS07925
gene id: 198467:AFK25_RS07925
uniprot id: A0A0A2SK25
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

198467:AFK25 RS08245
gene id: 198467:AFK25_RS08245
uniprot id: M5R7C3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

198467:AFK25 RS05665
gene id: 198467:AFK25_RS05665
uniprot id: A0A0A2SNF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS13935
gene id: 198467:AFK25_RS13935
uniprot id: M5QVF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS14250
gene id: 198467:AFK25_RS14250
uniprot id: A0A0A2SKK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS06320
gene id: 198467:AFK25_RS06320
uniprot id: A0A0A2SM29
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

198467:AFK25 RS11545
gene id: 198467:AFK25_RS11545
uniprot id: A0A0A2SIZ5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

198467:AFK25 RS00700
gene id: 198467:AFK25_RS00700
uniprot id: M5RAD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

198467:AFK25 RS05515
gene id: 198467:AFK25_RS05515
uniprot id: M5QYH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

198467:AFK25 RS05390
gene id: 198467:AFK25_RS05390
uniprot id: A0A0A2SMM6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

198467:AFK25 RS01990
gene id: 198467:AFK25_RS01990
uniprot id: A0A0A2T3P8
names: Similarity
messages: Belongs to the Fur family.

198467:AFK25 RS09960
gene id: 198467:AFK25_RS09960
uniprot id: A0A0A2SJY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

198467:AFK25 RS11940
gene id: 198467:AFK25_RS11940
uniprot id: M5R664
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

198467:AFK25 RS06700
gene id: 198467:AFK25_RS06700
uniprot id: A0A0A2T1K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

198467:AFK25 RS00620
gene id: 198467:AFK25_RS00620
uniprot id: M5QTS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

198467:AFK25 RS11375
gene id: 198467:AFK25_RS11375
uniprot id: A0A0A2T167
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

198467:AFK25 RS11225
gene id: 198467:AFK25_RS11225
uniprot id: M5R5S1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

198467:AFK25 RS09725
gene id: 198467:AFK25_RS09725
uniprot id: A0A0A2SY28
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

198467:AFK25 RS00585
gene id: 198467:AFK25_RS00585
uniprot id: A0A0A2SLV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

198467:AFK25 RS06385
gene id: 198467:AFK25_RS06385
uniprot id: A0A0A2T025
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS12855
gene id: 198467:AFK25_RS12855
uniprot id: M5R453
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

198467:AFK25 RS06770
gene id: 198467:AFK25_RS06770
uniprot id: A0A0A2SHE5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

198467:AFK25 RS01765
gene id: 198467:AFK25_RS01765
uniprot id: M5QWE2
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS01945
gene id: 198467:AFK25_RS01945
uniprot id: M5R8G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS05005
gene id: 198467:AFK25_RS05005
uniprot id: M5R8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

198467:AFK25 RS01955
gene id: 198467:AFK25_RS01955
uniprot id: A0A7U4NMG4
names: Similarity
messages: Belongs to the glutamate synthase family.

198467:AFK25 RS13815
gene id: 198467:AFK25_RS13815
uniprot id: M5QVL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

198467:AFK25 RS10070
gene id: 198467:AFK25_RS10070
uniprot id: M5R3M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS13845
gene id: 198467:AFK25_RS13845
uniprot id: A0A0A2SKU0
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS14145
gene id: 198467:AFK25_RS14145
uniprot id: M5R7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS12275
gene id: 198467:AFK25_RS12275
uniprot id: M5QTL2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

198467:AFK25 RS09020
gene id: 198467:AFK25_RS09020
uniprot id: A0A0A2SHT5
names: Caution
names: Similarity
messages: Belongs to the SleB family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

198467:AFK25 RS12985
gene id: 198467:AFK25_RS12985
uniprot id: A0A0A2SLR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

198467:AFK25 RS10755
gene id: 198467:AFK25_RS10755
uniprot id: M5QTF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS10910
gene id: 198467:AFK25_RS10910
uniprot id: M5QTI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

198467:AFK25 RS05530
gene id: 198467:AFK25_RS05530
uniprot id: M5RD10
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

198467:AFK25 RS02575
gene id: 198467:AFK25_RS02575
uniprot id: A0A0A2SQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

198467:AFK25 RS00285
gene id: 198467:AFK25_RS00285
uniprot id: M5QXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

198467:AFK25 RS10600
gene id: 198467:AFK25_RS10600
uniprot id: A0A0A2SJG7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. YrrT family.
messages: Could be a S-adenosyl-L-methionine-dependent methyltransferase.

198467:AFK25 RS06520
gene id: 198467:AFK25_RS06520
uniprot id: A0A0A2SFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

198467:AFK25 RS14540
gene id: 198467:AFK25_RS14540
uniprot id: M5QXA6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

198467:AFK25 RS06925
gene id: 198467:AFK25_RS06925
uniprot id: A0A0A2SHC1
names: Similarity
messages: Belongs to the EamA transporter family.

198467:AFK25 RS12745
gene id: 198467:AFK25_RS12745
uniprot id: M5R7V2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

198467:AFK25 RS06330
gene id: 198467:AFK25_RS06330
uniprot id: A0A0A2SN03
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

198467:AFK25 RS08315
gene id: 198467:AFK25_RS08315
uniprot id: A0A0A2SFS2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

198467:AFK25 RS10730
gene id: 198467:AFK25_RS10730
uniprot id: A0A0A2SFD0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

198467:AFK25 RS08920
gene id: 198467:AFK25_RS08920
uniprot id: M5R309
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

198467:AFK25 RS01060
gene id: 198467:AFK25_RS01060
uniprot id: A0A0A2SWM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS04250
gene id: 198467:AFK25_RS04250
uniprot id: A0A0A2SLD6
names: Similarity
messages: Belongs to the CdaR family.

198467:AFK25 RS03945
gene id: 198467:AFK25_RS03945
uniprot id: A0A0A2SWI0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).
messages: The active site is a redox-active disulfide bond.

198467:AFK25 RS07020
gene id: 198467:AFK25_RS07020
uniprot id: M5R6S4
names: Similarity
messages: Belongs to the acyltransferase 3 family.

198467:AFK25 RS13660
gene id: 198467:AFK25_RS13660
uniprot id: A0A7U4NRQ2
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

198467:AFK25 RS04630
gene id: 198467:AFK25_RS04630
uniprot id: A0A0A2T391
names: Subcellular Location Annotation
messages: Membrane

198467:AFK25 RS05010
gene id: 198467:AFK25_RS05010
uniprot id: A0A0A2SNN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

198467:AFK25 RS14245
gene id: 198467:AFK25_RS14245
uniprot id: A0A0A2SPR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

198467:AFK25 RS02990
gene id: 198467:AFK25_RS02990
uniprot id: A0A0A2SK08
names: Similarity
messages: Belongs to the SCO1/2 family.

198467:AFK25 RS14090
gene id: 198467:AFK25_RS14090
uniprot id: A0A0A2SPT8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

198467:AFK25 RS12195
gene id: 198467:AFK25_RS12195
uniprot id: A0A0A2SLQ0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.