191610:CATYP RS02325
gene id: 191610:CATYP_RS02325
uniprot id: A0A075TQI1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

191610:CATYP RS07400
gene id: 191610:CATYP_RS07400
uniprot id: A0A075TW54
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS05320
gene id: 191610:CATYP_RS05320
uniprot id: A0A075TVX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

191610:CATYP RS04165
gene id: 191610:CATYP_RS04165
uniprot id: A0A075TVG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

191610:CATYP RS04895
gene id: 191610:CATYP_RS04895
uniprot id: A0A075TV24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

191610:CATYP RS04265
gene id: 191610:CATYP_RS04265
uniprot id: A0A075U1N9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

191610:CATYP RS03990
gene id: 191610:CATYP_RS03990
uniprot id: A0A075U1J8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

191610:CATYP RS01660
gene id: 191610:CATYP_RS01660
uniprot id: A0A075TTR9
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS09995
gene id: 191610:CATYP_RS09995
uniprot id: A0A075TX81
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

191610:CATYP RS02095
gene id: 191610:CATYP_RS02095
uniprot id: A0A075U0S1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

191610:CATYP RS07035
gene id: 191610:CATYP_RS07035
uniprot id: A0A075TW40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

191610:CATYP RS00025
gene id: 191610:CATYP_RS00025
uniprot id: A0A075TTD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

191610:CATYP RS01575
gene id: 191610:CATYP_RS01575
uniprot id: A0A075U0I1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

191610:CATYP RS05985
gene id: 191610:CATYP_RS05985
uniprot id: A0A075TW63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS09970
gene id: 191610:CATYP_RS09970
uniprot id: A0A075TX72
names: Similarity
messages: Belongs to the thioredoxin family.

191610:CATYP RS05205
gene id: 191610:CATYP_RS05205
uniprot id: A0A075TVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

191610:CATYP RS07130
gene id: 191610:CATYP_RS07130
uniprot id: A0A075U2V4
names: Similarity
messages: Belongs to the YggT family.

191610:CATYP RS09860
gene id: 191610:CATYP_RS09860
uniprot id: A0A075TTE8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

191610:CATYP RS08040
gene id: 191610:CATYP_RS08040
uniprot id: A0A075TX56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

191610:CATYP RS06835
gene id: 191610:CATYP_RS06835
uniprot id: A0A075TWJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

191610:CATYP RS07820
gene id: 191610:CATYP_RS07820
uniprot id: A0A075TWF2
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS04615
gene id: 191610:CATYP_RS04615
uniprot id: A0A075TUY7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

191610:CATYP RS02460
gene id: 191610:CATYP_RS02460
uniprot id: A0A075TU37
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

191610:CATYP RS09245
gene id: 191610:CATYP_RS09245
uniprot id: A0A075TWY8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

191610:CATYP RS04580
gene id: 191610:CATYP_RS04580
uniprot id: A0A075TUY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

191610:CATYP RS05565
gene id: 191610:CATYP_RS05565
uniprot id: A0A075TVA9
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

191610:CATYP RS02285
gene id: 191610:CATYP_RS02285
uniprot id: A0A075TUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

191610:CATYP RS10290
gene id: 191610:CATYP_RS10290
uniprot id: A0A075U3R4
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS07065
gene id: 191610:CATYP_RS07065
uniprot id: A0A075U2U6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

191610:CATYP RS09105
gene id: 191610:CATYP_RS09105
uniprot id: A0A075TT25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

191610:CATYP RS05635
gene id: 191610:CATYP_RS05635
uniprot id: A0A075TVC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

191610:CATYP RS05010
gene id: 191610:CATYP_RS05010
uniprot id: A0A075TVR8
names: Similarity
messages: Belongs to the UPF0237 family.

191610:CATYP RS08610
gene id: 191610:CATYP_RS08610
uniprot id: A0A075TWP3
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

191610:CATYP RS00490
gene id: 191610:CATYP_RS00490
uniprot id: A0A075TTB0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

191610:CATYP RS02640
gene id: 191610:CATYP_RS02640
uniprot id: A0A075TU82
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

191610:CATYP RS08975
gene id: 191610:CATYP_RS08975
uniprot id: A0A075TWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

191610:CATYP RS02940
gene id: 191610:CATYP_RS02940
uniprot id: A0A075U132
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

191610:CATYP RS04185
gene id: 191610:CATYP_RS04185
uniprot id: A0A075TUT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

191610:CATYP RS06910
gene id: 191610:CATYP_RS06910
uniprot id: A0A075TS94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS10395
gene id: 191610:CATYP_RS10395
uniprot id: A0A075TX16
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

191610:CATYP RS06735
gene id: 191610:CATYP_RS06735
uniprot id: A0A075U2M9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

191610:CATYP RS05780
gene id: 191610:CATYP_RS05780
uniprot id: A0A075TVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS05245
gene id: 191610:CATYP_RS05245
uniprot id: A0A075TVW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS02310
gene id: 191610:CATYP_RS02310
uniprot id: A0A075TU18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

191610:CATYP RS04145
gene id: 191610:CATYP_RS04145
uniprot id: A0A075TUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

191610:CATYP RS02140
gene id: 191610:CATYP_RS02140
uniprot id: A0A075TTZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

191610:CATYP RS02755
gene id: 191610:CATYP_RS02755
uniprot id: A0A075TU80
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

191610:CATYP RS03995
gene id: 191610:CATYP_RS03995
uniprot id: A0A075TVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

191610:CATYP RS05520
gene id: 191610:CATYP_RS05520
uniprot id: A0A075TVA4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

191610:CATYP RS03160
gene id: 191610:CATYP_RS03160
uniprot id: A0A075U154
names: Similarity
messages: Belongs to the FPG family.

191610:CATYP RS03565
gene id: 191610:CATYP_RS03565
uniprot id: A0A075TUM9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

191610:CATYP RS07605
gene id: 191610:CATYP_RS07605
uniprot id: A0A075TWZ4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

191610:CATYP RS08295
gene id: 191610:CATYP_RS08295
uniprot id: A0A075TSR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

191610:CATYP RS02720
gene id: 191610:CATYP_RS02720
uniprot id: A0A075TQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

191610:CATYP RS09280
gene id: 191610:CATYP_RS09280
uniprot id: A0A075U3Q7
names: Similarity
messages: Belongs to the HIBADH-related family.

191610:CATYP RS01410
gene id: 191610:CATYP_RS01410
uniprot id: A0A075U0F4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

191610:CATYP RS07685
gene id: 191610:CATYP_RS07685
uniprot id: A0A075TSJ1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

191610:CATYP RS02080
gene id: 191610:CATYP_RS02080
uniprot id: A0A075TQD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

191610:CATYP RS10095
gene id: 191610:CATYP_RS10095
uniprot id: A0A075TX96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS04100
gene id: 191610:CATYP_RS04100
uniprot id: A0A075TUS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

191610:CATYP RS01945
gene id: 191610:CATYP_RS01945
uniprot id: A0A075U0P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

191610:CATYP RS06100
gene id: 191610:CATYP_RS06100
uniprot id: A0A075TVJ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

191610:CATYP RS04310
gene id: 191610:CATYP_RS04310
uniprot id: A0A075TRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

191610:CATYP RS01875
gene id: 191610:CATYP_RS01875
uniprot id: A0A075TQA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

191610:CATYP RS03875
gene id: 191610:CATYP_RS03875
uniprot id: A0A075TR64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

191610:CATYP RS04125
gene id: 191610:CATYP_RS04125
uniprot id: A0A075TUT0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

191610:CATYP RS06930
gene id: 191610:CATYP_RS06930
uniprot id: A0A075U2T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

191610:CATYP RS02530
gene id: 191610:CATYP_RS02530
uniprot id: A0A075TU45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

191610:CATYP RS07635
gene id: 191610:CATYP_RS07635
uniprot id: A0A075TSI2
names: Similarity
messages: Belongs to the Fur family.

191610:CATYP RS04800
gene id: 191610:CATYP_RS04800
uniprot id: A0A075TV10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

191610:CATYP RS04610
gene id: 191610:CATYP_RS04610
uniprot id: A0A075TV09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS04570
gene id: 191610:CATYP_RS04570
uniprot id: A0A075TV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

191610:CATYP RS07690
gene id: 191610:CATYP_RS07690
uniprot id: A0A075TW99
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

191610:CATYP RS03910
gene id: 191610:CATYP_RS03910
uniprot id: A0A075TR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS06960
gene id: 191610:CATYP_RS06960
uniprot id: A0A075U2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

191610:CATYP RS07665
gene id: 191610:CATYP_RS07665
uniprot id: A0A075TW94
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS08070
gene id: 191610:CATYP_RS08070
uniprot id: A0A075U388
names: Similarity
messages: Belongs to the LacAB/RpiB family.

191610:CATYP RS08960
gene id: 191610:CATYP_RS08960
uniprot id: A0A075U3M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

191610:CATYP RS08345
gene id: 191610:CATYP_RS08345
uniprot id: A0A075U3D0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

191610:CATYP RS02965
gene id: 191610:CATYP_RS02965
uniprot id: A0A075TUB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

191610:CATYP RS10200
gene id: 191610:CATYP_RS10200
uniprot id: A0A075TXB3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

191610:CATYP RS01310
gene id: 191610:CATYP_RS01310
uniprot id: A0A075TTN0
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS04930
gene id: 191610:CATYP_RS04930
uniprot id: A0A075TV27
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

191610:CATYP RS07385
gene id: 191610:CATYP_RS07385
uniprot id: A0A075U2Y8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

191610:CATYP RS08435
gene id: 191610:CATYP_RS08435
uniprot id: A0A075U3E7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

191610:CATYP RS09310
gene id: 191610:CATYP_RS09310
uniprot id: A0A075TWZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS04205
gene id: 191610:CATYP_RS04205
uniprot id: A0A075TRB0
names: Similarity
messages: Belongs to the PspA/IM30 family.

191610:CATYP RS02545
gene id: 191610:CATYP_RS02545
uniprot id: A0A075TQL5
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

191610:CATYP RS00505
gene id: 191610:CATYP_RS00505
uniprot id: A0A075U045
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

191610:CATYP RS06200
gene id: 191610:CATYP_RS06200
uniprot id: A0A075TVK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

191610:CATYP RS00465
gene id: 191610:CATYP_RS00465
uniprot id: A0A075U041
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS03220
gene id: 191610:CATYP_RS03220
uniprot id: A0A075TUE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

191610:CATYP RS03525
gene id: 191610:CATYP_RS03525
uniprot id: A0A075TUK9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

191610:CATYP RS09775
gene id: 191610:CATYP_RS09775
uniprot id: A0A075TX50
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

191610:CATYP RS06175
gene id: 191610:CATYP_RS06175
uniprot id: A0A075TVL1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

191610:CATYP RS02190
gene id: 191610:CATYP_RS02190
uniprot id: A0A075TU02
names: Similarity
messages: Belongs to the CFA/CMAS family.

191610:CATYP RS01465
gene id: 191610:CATYP_RS01465
uniprot id: A0A075U0G4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

191610:CATYP RS08985
gene id: 191610:CATYP_RS08985
uniprot id: A0A075U3N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

191610:CATYP RS02960
gene id: 191610:CATYP_RS02960
uniprot id: A0A075TUE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

191610:CATYP RS01955
gene id: 191610:CATYP_RS01955
uniprot id: A0A075TQB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

191610:CATYP RS03045
gene id: 191610:CATYP_RS03045
uniprot id: A0A075TUC5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

191610:CATYP RS02525
gene id: 191610:CATYP_RS02525
uniprot id: A0A075TU59
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

191610:CATYP RS08730
gene id: 191610:CATYP_RS08730
uniprot id: A0A075TWR4
names: Similarity
messages: Belongs to the peptidase C1 family.

191610:CATYP RS09285
gene id: 191610:CATYP_RS09285
uniprot id: A0A075TXN4
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

191610:CATYP RS02305
gene id: 191610:CATYP_RS02305
uniprot id: A0A075TU17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

191610:CATYP RS05055
gene id: 191610:CATYP_RS05055
uniprot id: A0A075TRK4
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS09050
gene id: 191610:CATYP_RS09050
uniprot id: A0A075U3N8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

191610:CATYP RS03335
gene id: 191610:CATYP_RS03335
uniprot id: A0A075TV32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

191610:CATYP RS05740
gene id: 191610:CATYP_RS05740
uniprot id: A0A075TRU4
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS01910
gene id: 191610:CATYP_RS01910
uniprot id: A0A075TTU5
names: Similarity
messages: Belongs to the asp23 family.

191610:CATYP RS05590
gene id: 191610:CATYP_RS05590
uniprot id: A0A075TVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS04960
gene id: 191610:CATYP_RS04960
uniprot id: A0A075TV36
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

191610:CATYP RS10390
gene id: 191610:CATYP_RS10390
uniprot id: A0A075U465
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

191610:CATYP RS06245
gene id: 191610:CATYP_RS06245
uniprot id: A0A075TS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

191610:CATYP RS05970
gene id: 191610:CATYP_RS05970
uniprot id: A0A075TVI1
names: Similarity
messages: Belongs to the peptidase S33 family.

191610:CATYP RS02220
gene id: 191610:CATYP_RS02220
uniprot id: A0A075TTZ9
names: Similarity
messages: Belongs to the WXG100 family.

191610:CATYP RS04300
gene id: 191610:CATYP_RS04300
uniprot id: A0A075U1P6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

191610:CATYP RS07925
gene id: 191610:CATYP_RS07925
uniprot id: A0A075U361
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

191610:CATYP RS02070
gene id: 191610:CATYP_RS02070
uniprot id: A0A075U0R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

191610:CATYP RS08045
gene id: 191610:CATYP_RS08045
uniprot id: A0A075TSP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

191610:CATYP RS08130
gene id: 191610:CATYP_RS08130
uniprot id: A0A075TSQ2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

191610:CATYP RS08995
gene id: 191610:CATYP_RS08995
uniprot id: A0A075TT17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

191610:CATYP RS07125
gene id: 191610:CATYP_RS07125
uniprot id: A0A075TW66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

191610:CATYP RS03750
gene id: 191610:CATYP_RS03750
uniprot id: A0A075TR54
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

191610:CATYP RS01625
gene id: 191610:CATYP_RS01625
uniprot id: A0A075TQ71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS04925
gene id: 191610:CATYP_RS04925
uniprot id: A0A075TV34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

191610:CATYP RS05910
gene id: 191610:CATYP_RS05910
uniprot id: A0A075TVH0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

191610:CATYP RS06490
gene id: 191610:CATYP_RS06490
uniprot id: A0A075TWE8
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS08375
gene id: 191610:CATYP_RS08375
uniprot id: A0A075U3D5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

191610:CATYP RS00885
gene id: 191610:CATYP_RS00885
uniprot id: A0A075TTJ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS06195
gene id: 191610:CATYP_RS06195
uniprot id: A0A075TRZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

191610:CATYP RS05380
gene id: 191610:CATYP_RS05380
uniprot id: A0A075U250
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS05140
gene id: 191610:CATYP_RS05140
uniprot id: A0A075U212
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

191610:CATYP RS04155
gene id: 191610:CATYP_RS04155
uniprot id: A0A075TUT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

191610:CATYP RS02455
gene id: 191610:CATYP_RS02455
uniprot id: A0A075TU49
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS10045
gene id: 191610:CATYP_RS10045
uniprot id: A0A075U412
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

191610:CATYP RS08705
gene id: 191610:CATYP_RS08705
uniprot id: A0A075U3I4
names: Similarity
messages: Belongs to the GARS family.

191610:CATYP RS00100
gene id: 191610:CATYP_RS00100
uniprot id: A0A075TTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS04015
gene id: 191610:CATYP_RS04015
uniprot id: A0A075U1K4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

191610:CATYP RS05180
gene id: 191610:CATYP_RS05180
uniprot id: A0A075TV57
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

191610:CATYP RS07995
gene id: 191610:CATYP_RS07995
uniprot id: A0A075TWG8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

191610:CATYP RS05090
gene id: 191610:CATYP_RS05090
uniprot id: A0A075TRK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

191610:CATYP RS06725
gene id: 191610:CATYP_RS06725
uniprot id: A0A075TVV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

191610:CATYP RS02215
gene id: 191610:CATYP_RS02215
uniprot id: A0A075TQG1
names: Similarity
messages: Belongs to the WXG100 family.

191610:CATYP RS03870
gene id: 191610:CATYP_RS03870
uniprot id: A0A075TVC0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

191610:CATYP RS07530
gene id: 191610:CATYP_RS07530
uniprot id: A0A075TWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

191610:CATYP RS02710
gene id: 191610:CATYP_RS02710
uniprot id: A0A075U104
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

191610:CATYP RS04450
gene id: 191610:CATYP_RS04450
uniprot id: A0A075TRD9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

191610:CATYP RS08915
gene id: 191610:CATYP_RS08915
uniprot id: A0A075U3M0
names: Similarity
messages: Belongs to the pantothenate synthetase family.

191610:CATYP RS07655
gene id: 191610:CATYP_RS07655
uniprot id: A0A075TX04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

191610:CATYP RS06115
gene id: 191610:CATYP_RS06115
uniprot id: A0A075TRY7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

191610:CATYP RS01680
gene id: 191610:CATYP_RS01680
uniprot id: A0A075TQ80
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

191610:CATYP RS01895
gene id: 191610:CATYP_RS01895
uniprot id: A0A075U0N5
names: Similarity
messages: Belongs to the asp23 family.

191610:CATYP RS03280
gene id: 191610:CATYP_RS03280
uniprot id: A0A075TUG1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

191610:CATYP RS05300
gene id: 191610:CATYP_RS05300
uniprot id: A0A075TV69
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

191610:CATYP RS01375
gene id: 191610:CATYP_RS01375
uniprot id: A0A075U0F1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

191610:CATYP RS05595
gene id: 191610:CATYP_RS05595
uniprot id: A0A075TRS4
names: Similarity
messages: Belongs to the UPF0434 family.

191610:CATYP RS05110
gene id: 191610:CATYP_RS05110
uniprot id: A0A075TVT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

191610:CATYP RS03285
gene id: 191610:CATYP_RS03285
uniprot id: A0A075U176
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

191610:CATYP RS00790
gene id: 191610:CATYP_RS00790
uniprot id: A0A075U072
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

191610:CATYP RS00535
gene id: 191610:CATYP_RS00535
uniprot id: A0A075TTB5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

191610:CATYP RS02655
gene id: 191610:CATYP_RS02655
uniprot id: A0A075TUT7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

191610:CATYP RS05275
gene id: 191610:CATYP_RS05275
uniprot id: A0A075U233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS04375
gene id: 191610:CATYP_RS04375
uniprot id: A0A075TUZ3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

191610:CATYP RS07430
gene id: 191610:CATYP_RS07430
uniprot id: A0A075TWB7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

191610:CATYP RS01535
gene id: 191610:CATYP_RS01535
uniprot id: A0A075TQ55
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

191610:CATYP RS09210
gene id: 191610:CATYP_RS09210
uniprot id: A0A075U3Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

191610:CATYP RS09980
gene id: 191610:CATYP_RS09980
uniprot id: A0A075U3Z7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

191610:CATYP RS01960
gene id: 191610:CATYP_RS01960
uniprot id: A0A075TTV5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

191610:CATYP RS02000
gene id: 191610:CATYP_RS02000
uniprot id: A0A075TTX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

191610:CATYP RS01695
gene id: 191610:CATYP_RS01695
uniprot id: A0A075U0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

191610:CATYP RS04380
gene id: 191610:CATYP_RS04380
uniprot id: A0A075TUW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS05105
gene id: 191610:CATYP_RS05105
uniprot id: A0A075U206
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

191610:CATYP RS03600
gene id: 191610:CATYP_RS03600
uniprot id: A0A075U1F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS01840
gene id: 191610:CATYP_RS01840
uniprot id: A0A075U0M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

191610:CATYP RS07380
gene id: 191610:CATYP_RS07380
uniprot id: A0A075TWA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

191610:CATYP RS10145
gene id: 191610:CATYP_RS10145
uniprot id: A0A075U429
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS02155
gene id: 191610:CATYP_RS02155
uniprot id: A0A075TQF0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

191610:CATYP RS03770
gene id: 191610:CATYP_RS03770
uniprot id: A0A075U1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

191610:CATYP RS10255
gene id: 191610:CATYP_RS10255
uniprot id: A0A075TY97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

191610:CATYP RS05170
gene id: 191610:CATYP_RS05170
uniprot id: A0A075TVU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

191610:CATYP RS07055
gene id: 191610:CATYP_RS07055
uniprot id: A0A075TW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS05715
gene id: 191610:CATYP_RS05715
uniprot id: A0A075TRT9
names: Similarity
messages: Belongs to the universal stress protein A family.

191610:CATYP RS06105
gene id: 191610:CATYP_RS06105
uniprot id: A0A075U2E7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

191610:CATYP RS05725
gene id: 191610:CATYP_RS05725
uniprot id: A0A075TVF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

191610:CATYP RS01865
gene id: 191610:CATYP_RS01865
uniprot id: A0A075U0M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

191610:CATYP RS05835
gene id: 191610:CATYP_RS05835
uniprot id: A0A075TVF9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

191610:CATYP RS03945
gene id: 191610:CATYP_RS03945
uniprot id: A0A075TUS8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

191610:CATYP RS01940
gene id: 191610:CATYP_RS01940
uniprot id: A0A075TTW0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

191610:CATYP RS07985
gene id: 191610:CATYP_RS07985
uniprot id: A0A075TSN5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

191610:CATYP RS09740
gene id: 191610:CATYP_RS09740
uniprot id: A0A075TX45
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

191610:CATYP RS03245
gene id: 191610:CATYP_RS03245
uniprot id: A0A075TUF5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

191610:CATYP RS00165
gene id: 191610:CATYP_RS00165
uniprot id: A0A075TPQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

191610:CATYP RS09795
gene id: 191610:CATYP_RS09795
uniprot id: A0A075TX47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

191610:CATYP RS08560
gene id: 191610:CATYP_RS08560
uniprot id: A0A075TXB5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

191610:CATYP RS03800
gene id: 191610:CATYP_RS03800
uniprot id: A0A075U1H3
names: Similarity
messages: Belongs to the AccD/PCCB family.

191610:CATYP RS00230
gene id: 191610:CATYP_RS00230
uniprot id: A0A075TTV1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

191610:CATYP RS03635
gene id: 191610:CATYP_RS03635
uniprot id: A0A075U1F6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

191610:CATYP RS08470
gene id: 191610:CATYP_RS08470
uniprot id: A0A075U3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

191610:CATYP RS08945
gene id: 191610:CATYP_RS08945
uniprot id: A0A075TWQ0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

191610:CATYP RS04890
gene id: 191610:CATYP_RS04890
uniprot id: A0A075TV30
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

191610:CATYP RS05625
gene id: 191610:CATYP_RS05625
uniprot id: A0A075TRS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

191610:CATYP RS09065
gene id: 191610:CATYP_RS09065
uniprot id: A0A075TWS3
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS01370
gene id: 191610:CATYP_RS01370
uniprot id: A0A075TTN8
names: Subcellular Location Annotation
messages: Cytoplasm

191610:CATYP RS03850
gene id: 191610:CATYP_RS03850
uniprot id: A0A075TUN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

191610:CATYP RS02695
gene id: 191610:CATYP_RS02695
uniprot id: A0A075TU72
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

191610:CATYP RS02670
gene id: 191610:CATYP_RS02670
uniprot id: A0A075TU67
names: Similarity
messages: Belongs to the phosphohexose mutase family.

191610:CATYP RS10185
gene id: 191610:CATYP_RS10185
uniprot id: A0A075TY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

191610:CATYP RS03880
gene id: 191610:CATYP_RS03880
uniprot id: A0A075TUS0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

191610:CATYP RS02135
gene id: 191610:CATYP_RS02135
uniprot id: A0A075TTY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

191610:CATYP RS07525
gene id: 191610:CATYP_RS07525
uniprot id: A0A075TW73
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

191610:CATYP RS06455
gene id: 191610:CATYP_RS06455
uniprot id: A0A075U2I8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

191610:CATYP RS08350
gene id: 191610:CATYP_RS08350
uniprot id: A0A075TX94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

191610:CATYP RS03495
gene id: 191610:CATYP_RS03495
uniprot id: A0A075TUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

191610:CATYP RS09025
gene id: 191610:CATYP_RS09025
uniprot id: A0A075TXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS02985
gene id: 191610:CATYP_RS02985
uniprot id: A0A075TQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

191610:CATYP RS08940
gene id: 191610:CATYP_RS08940
uniprot id: A0A075TT13
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

191610:CATYP RS00585
gene id: 191610:CATYP_RS00585
uniprot id: A0A075TTZ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS03470
gene id: 191610:CATYP_RS03470
uniprot id: A0A075TR25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

191610:CATYP RS02160
gene id: 191610:CATYP_RS02160
uniprot id: A0A075TTY8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

191610:CATYP RS10050
gene id: 191610:CATYP_RS10050
uniprot id: A0A075TY39
names: Similarity
messages: Belongs to the UPF0371 family.

191610:CATYP RS00930
gene id: 191610:CATYP_RS00930
uniprot id: A0A075TTF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS02345
gene id: 191610:CATYP_RS02345
uniprot id: A0A075TUN4
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

191610:CATYP RS01390
gene id: 191610:CATYP_RS01390
uniprot id: A0A075TQ38
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

191610:CATYP RS01630
gene id: 191610:CATYP_RS01630
uniprot id: A0A075TTR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

191610:CATYP RS07550
gene id: 191610:CATYP_RS07550
uniprot id: A0A075TW76
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS04305
gene id: 191610:CATYP_RS04305
uniprot id: A0A075TVI4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

191610:CATYP RS08370
gene id: 191610:CATYP_RS08370
uniprot id: A0A075TWL6
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

191610:CATYP RS06310
gene id: 191610:CATYP_RS06310
uniprot id: A0A075TVN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS08290
gene id: 191610:CATYP_RS08290
uniprot id: A0A075TX82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

191610:CATYP RS04695
gene id: 191610:CATYP_RS04695
uniprot id: A0A075U1U2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

191610:CATYP RS02825
gene id: 191610:CATYP_RS02825
uniprot id: A0A075TQQ7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

191610:CATYP RS03325
gene id: 191610:CATYP_RS03325
uniprot id: A0A075U181
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

191610:CATYP RS08645
gene id: 191610:CATYP_RS08645
uniprot id: A0A075U3H5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

191610:CATYP RS02900
gene id: 191610:CATYP_RS02900
uniprot id: A0A075TQR6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

191610:CATYP RS01920
gene id: 191610:CATYP_RS01920
uniprot id: A0A075U0P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

191610:CATYP RS02925
gene id: 191610:CATYP_RS02925
uniprot id: A0A075TQS2
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

191610:CATYP RS02905
gene id: 191610:CATYP_RS02905
uniprot id: A0A075TUC9
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

191610:CATYP RS00185
gene id: 191610:CATYP_RS00185
uniprot id: A0A075U014
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS02610
gene id: 191610:CATYP_RS02610
uniprot id: A0A075TU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

191610:CATYP RS02060
gene id: 191610:CATYP_RS02060
uniprot id: A0A075TTW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

191610:CATYP RS00985
gene id: 191610:CATYP_RS00985
uniprot id: A0A075TU33
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS00005
gene id: 191610:CATYP_RS00005
uniprot id: A0A075TZV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

191610:CATYP RS04915
gene id: 191610:CATYP_RS04915
uniprot id: A0A075TVQ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS00250
gene id: 191610:CATYP_RS00250
uniprot id: A0A075TTG3
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS01825
gene id: 191610:CATYP_RS01825
uniprot id: A0A075TQ95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

191610:CATYP RS05645
gene id: 191610:CATYP_RS05645
uniprot id: A0A075TVD4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

191610:CATYP RS01345
gene id: 191610:CATYP_RS01345
uniprot id: A0A075TTN4
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS01855
gene id: 191610:CATYP_RS01855
uniprot id: A0A075TTU1
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS04970
gene id: 191610:CATYP_RS04970
uniprot id: A0A075U1Y6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

191610:CATYP RS04340
gene id: 191610:CATYP_RS04340
uniprot id: A0A075TUY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

191610:CATYP RS00630
gene id: 191610:CATYP_RS00630
uniprot id: A0A075TTZ5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

191610:CATYP RS08330
gene id: 191610:CATYP_RS08330
uniprot id: A0A075TSS3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

191610:CATYP RS00270
gene id: 191610:CATYP_RS00270
uniprot id: A0A075TPS2
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS04765
gene id: 191610:CATYP_RS04765
uniprot id: A0A075TRG9
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

191610:CATYP RS08910
gene id: 191610:CATYP_RS08910
uniprot id: A0A075TWU6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS03075
gene id: 191610:CATYP_RS03075
uniprot id: A0A075TQT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

191610:CATYP RS00695
gene id: 191610:CATYP_RS00695
uniprot id: A0A075TTI5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

191610:CATYP RS05580
gene id: 191610:CATYP_RS05580
uniprot id: A0A075U282
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

191610:CATYP RS08845
gene id: 191610:CATYP_RS08845
uniprot id: A0A075U3K8
names: Similarity
messages: Belongs to the Nth/MutY family.

191610:CATYP RS05310
gene id: 191610:CATYP_RS05310
uniprot id: A0A075TV76
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS08380
gene id: 191610:CATYP_RS08380
uniprot id: A0A075TX99
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

191610:CATYP RS01965
gene id: 191610:CATYP_RS01965
uniprot id: A0A075TTW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

191610:CATYP RS02400
gene id: 191610:CATYP_RS02400
uniprot id: A0A075TU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

191610:CATYP RS07175
gene id: 191610:CATYP_RS07175
uniprot id: A0A075TSC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

191610:CATYP RS03980
gene id: 191610:CATYP_RS03980
uniprot id: A0A075TUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

191610:CATYP RS05825
gene id: 191610:CATYP_RS05825
uniprot id: A0A075TW37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

191610:CATYP RS07020
gene id: 191610:CATYP_RS07020
uniprot id: A0A075TW10
names: Similarity
messages: Belongs to the IMPACT family.

191610:CATYP RS08180
gene id: 191610:CATYP_RS08180
uniprot id: A0A075TSQ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

191610:CATYP RS07535
gene id: 191610:CATYP_RS07535
uniprot id: A0A075U312
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

191610:CATYP RS06450
gene id: 191610:CATYP_RS06450
uniprot id: A0A075TVQ7
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS03640
gene id: 191610:CATYP_RS03640
uniprot id: A0A075TV97
names: Similarity
messages: Belongs to the FBPase class 2 family.

191610:CATYP RS09930
gene id: 191610:CATYP_RS09930
uniprot id: A0A075TX71
names: Similarity
messages: Belongs to the universal stress protein A family.

191610:CATYP RS01700
gene id: 191610:CATYP_RS01700
uniprot id: A0A075TUF2
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS04775
gene id: 191610:CATYP_RS04775
uniprot id: A0A075TV06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

191610:CATYP RS08035
gene id: 191610:CATYP_RS08035
uniprot id: A0A075U380
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

191610:CATYP RS07625
gene id: 191610:CATYP_RS07625
uniprot id: A0A075U324
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS07210
gene id: 191610:CATYP_RS07210
uniprot id: A0A075TWS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

191610:CATYP RS04415
gene id: 191610:CATYP_RS04415
uniprot id: A0A075TRD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

191610:CATYP RS09490
gene id: 191610:CATYP_RS09490
uniprot id: A0A075U465
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

191610:CATYP RS10055
gene id: 191610:CATYP_RS10055
uniprot id: A0A075TTI9
names: Similarity
messages: Belongs to the Dps family.

191610:CATYP RS04005
gene id: 191610:CATYP_RS04005
uniprot id: A0A075TUT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

191610:CATYP RS07330
gene id: 191610:CATYP_RS07330
uniprot id: A0A075TSD9
names: Similarity
messages: Belongs to the asparagine synthetase family.

191610:CATYP RS05690
gene id: 191610:CATYP_RS05690
uniprot id: A0A075TRT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

191610:CATYP RS03575
gene id: 191610:CATYP_RS03575
uniprot id: A0A075U1E7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

191610:CATYP RS04835
gene id: 191610:CATYP_RS04835
uniprot id: A0A075TV14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

191610:CATYP RS06940
gene id: 191610:CATYP_RS06940
uniprot id: A0A075TS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

191610:CATYP RS05810
gene id: 191610:CATYP_RS05810
uniprot id: A0A075TVG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

191610:CATYP RS06250
gene id: 191610:CATYP_RS06250
uniprot id: A0A075TVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

191610:CATYP RS08890
gene id: 191610:CATYP_RS08890
uniprot id: A0A075U3L4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

191610:CATYP RS05675
gene id: 191610:CATYP_RS05675
uniprot id: A0A075TVE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

191610:CATYP RS09115
gene id: 191610:CATYP_RS09115
uniprot id: A0A075TWX2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

191610:CATYP RS00010
gene id: 191610:CATYP_RS00010
uniprot id: A0A075TTQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

191610:CATYP RS09965
gene id: 191610:CATYP_RS09965
uniprot id: A0A075TTG2
names: Similarity
messages: Belongs to the PspA/IM30 family.

191610:CATYP RS06260
gene id: 191610:CATYP_RS06260
uniprot id: A0A075U2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

191610:CATYP RS06755
gene id: 191610:CATYP_RS06755
uniprot id: A0A075TVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

191610:CATYP RS05005
gene id: 191610:CATYP_RS05005
uniprot id: A0A075U1Z1
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

191610:CATYP RS08460
gene id: 191610:CATYP_RS08460
uniprot id: A0A075TWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS04820
gene id: 191610:CATYP_RS04820
uniprot id: A0A075TRH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS01275
gene id: 191610:CATYP_RS01275
uniprot id: A0A075TQ26
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

191610:CATYP RS02600
gene id: 191610:CATYP_RS02600
uniprot id: A0A075TQM4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

191610:CATYP RS05620
gene id: 191610:CATYP_RS05620
uniprot id: A0A075TW04
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

191610:CATYP RS04805
gene id: 191610:CATYP_RS04805
uniprot id: A0A075U1V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

191610:CATYP RS08565
gene id: 191610:CATYP_RS08565
uniprot id: A0A075TSV7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

191610:CATYP RS09500
gene id: 191610:CATYP_RS09500
uniprot id: A0A075U3S6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

191610:CATYP RS01980
gene id: 191610:CATYP_RS01980
uniprot id: A0A075TQC3
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS08080
gene id: 191610:CATYP_RS08080
uniprot id: A0A075TSP8
names: Similarity
messages: Belongs to the peptidase M1 family.

191610:CATYP RS04230
gene id: 191610:CATYP_RS04230
uniprot id: A0A075TVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

191610:CATYP RS07450
gene id: 191610:CATYP_RS07450
uniprot id: A0A075TWW8
names: Similarity
messages: Belongs to the glutamine synthetase family.

191610:CATYP RS05665
gene id: 191610:CATYP_RS05665
uniprot id: A0A075TRT2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

191610:CATYP RS10160
gene id: 191610:CATYP_RS10160
uniprot id: A0A075TY57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

191610:CATYP RS03845
gene id: 191610:CATYP_RS03845
uniprot id: A0A075TUR5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

191610:CATYP RS02315
gene id: 191610:CATYP_RS02315
uniprot id: A0A075U0V2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

191610:CATYP RS09010
gene id: 191610:CATYP_RS09010
uniprot id: A0A075TWW0
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS05650
gene id: 191610:CATYP_RS05650
uniprot id: A0A075U290
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

191610:CATYP RS04370
gene id: 191610:CATYP_RS04370
uniprot id: A0A075TRD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS07970
gene id: 191610:CATYP_RS07970
uniprot id: A0A075TWG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

191610:CATYP RS00895
gene id: 191610:CATYP_RS00895
uniprot id: A0A075TTF1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

191610:CATYP RS05670
gene id: 191610:CATYP_RS05670
uniprot id: A0A075TVC8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

191610:CATYP RS08815
gene id: 191610:CATYP_RS08815
uniprot id: A0A075U3K2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

191610:CATYP RS06240
gene id: 191610:CATYP_RS06240
uniprot id: A0A075TW98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

191610:CATYP RS02105
gene id: 191610:CATYP_RS02105
uniprot id: A0A075TQE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

191610:CATYP RS06090
gene id: 191610:CATYP_RS06090
uniprot id: A0A075TVJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS07375
gene id: 191610:CATYP_RS07375
uniprot id: A0A075TW51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

191610:CATYP RS06720
gene id: 191610:CATYP_RS06720
uniprot id: A0A075TVU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

191610:CATYP RS04880
gene id: 191610:CATYP_RS04880
uniprot id: A0A075TVQ1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

191610:CATYP RS08475
gene id: 191610:CATYP_RS08475
uniprot id: A0A075TXB1
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS06665
gene id: 191610:CATYP_RS06665
uniprot id: A0A075TWH0
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

191610:CATYP RS00880
gene id: 191610:CATYP_RS00880
uniprot id: A0A075TPY3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

191610:CATYP RS07135
gene id: 191610:CATYP_RS07135
uniprot id: A0A075TWR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

191610:CATYP RS04000
gene id: 191610:CATYP_RS04000
uniprot id: A0A075TR74
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS04290
gene id: 191610:CATYP_RS04290
uniprot id: A0A075TUX8
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS09455
gene id: 191610:CATYP_RS09455
uniprot id: A0A075TWZ0
names: Similarity
messages: Belongs to the peptidase S14 family.

191610:CATYP RS08700
gene id: 191610:CATYP_RS08700
uniprot id: A0A075TWQ8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

191610:CATYP RS08775
gene id: 191610:CATYP_RS08775
uniprot id: A0A075TWR9
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

191610:CATYP RS09165
gene id: 191610:CATYP_RS09165
uniprot id: A0A075TT34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

191610:CATYP RS04830
gene id: 191610:CATYP_RS04830
uniprot id: A0A075TV26
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

191610:CATYP RS08285
gene id: 191610:CATYP_RS08285
uniprot id: A0A075U3B8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

191610:CATYP RS01670
gene id: 191610:CATYP_RS01670
uniprot id: A0A075U0J5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

191610:CATYP RS01380
gene id: 191610:CATYP_RS01380
uniprot id: A0A075TU98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

191610:CATYP RS01860
gene id: 191610:CATYP_RS01860
uniprot id: A0A075TTU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

191610:CATYP RS07920
gene id: 191610:CATYP_RS07920
uniprot id: A0A075TWG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

191610:CATYP RS02580
gene id: 191610:CATYP_RS02580
uniprot id: A0A075TU70
names: Similarity
messages: Belongs to the AccD/PCCB family.

191610:CATYP RS09925
gene id: 191610:CATYP_RS09925
uniprot id: A0A075TX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

191610:CATYP RS07740
gene id: 191610:CATYP_RS07740
uniprot id: A0A075TX19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

191610:CATYP RS02475
gene id: 191610:CATYP_RS02475
uniprot id: A0A075TUQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS07795
gene id: 191610:CATYP_RS07795
uniprot id: A0A075TX24
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

191610:CATYP RS04770
gene id: 191610:CATYP_RS04770
uniprot id: A0A075TV20
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

191610:CATYP RS07160
gene id: 191610:CATYP_RS07160
uniprot id: A0A075U2V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

191610:CATYP RS08020
gene id: 191610:CATYP_RS08020
uniprot id: A0A075TWE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

191610:CATYP RS08695
gene id: 191610:CATYP_RS08695
uniprot id: A0A075TWL8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

191610:CATYP RS08015
gene id: 191610:CATYP_RS08015
uniprot id: A0A075TSP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

191610:CATYP RS02040
gene id: 191610:CATYP_RS02040
uniprot id: A0A075TTX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

191610:CATYP RS09360
gene id: 191610:CATYP_RS09360
uniprot id: A0A075U3R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

191610:CATYP RS02570
gene id: 191610:CATYP_RS02570
uniprot id: A0A075TUS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

191610:CATYP RS08195
gene id: 191610:CATYP_RS08195
uniprot id: A0A075TWJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

191610:CATYP RS09270
gene id: 191610:CATYP_RS09270
uniprot id: A0A075TWV9
names: Similarity
messages: Belongs to the peptidase C56 family.

191610:CATYP RS07250
gene id: 191610:CATYP_RS07250
uniprot id: A0A075TSC8
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

191610:CATYP RS03240
gene id: 191610:CATYP_RS03240
uniprot id: A0A075TUI3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

191610:CATYP RS00415
gene id: 191610:CATYP_RS00415
uniprot id: A0A075TTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS07150
gene id: 191610:CATYP_RS07150
uniprot id: A0A075TW71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

191610:CATYP RS05765
gene id: 191610:CATYP_RS05765
uniprot id: A0A075TW26
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

191610:CATYP RS02805
gene id: 191610:CATYP_RS02805
uniprot id: A0A075TUB3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

191610:CATYP RS03355
gene id: 191610:CATYP_RS03355
uniprot id: A0A075TUJ8
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

191610:CATYP RS02120
gene id: 191610:CATYP_RS02120
uniprot id: A0A075U0S5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

191610:CATYP RS08795
gene id: 191610:CATYP_RS08795
uniprot id: A0A075TXF1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

191610:CATYP RS09130
gene id: 191610:CATYP_RS09130
uniprot id: A0A075TXK5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

191610:CATYP RS07930
gene id: 191610:CATYP_RS07930
uniprot id: A0A075TX40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

191610:CATYP RS01295
gene id: 191610:CATYP_RS01295
uniprot id: A0A075TU83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

191610:CATYP RS04090
gene id: 191610:CATYP_RS04090
uniprot id: A0A075TR82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

191610:CATYP RS04070
gene id: 191610:CATYP_RS04070
uniprot id: A0A075TUR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS05990
gene id: 191610:CATYP_RS05990
uniprot id: A0A075TRX6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

191610:CATYP RS03090
gene id: 191610:CATYP_RS03090
uniprot id: A0A075TUF9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

191610:CATYP RS08225
gene id: 191610:CATYP_RS08225
uniprot id: A0A075TWG2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

191610:CATYP RS02300
gene id: 191610:CATYP_RS02300
uniprot id: A0A075TQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

191610:CATYP RS04920
gene id: 191610:CATYP_RS04920
uniprot id: A0A075TRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

191610:CATYP RS01460
gene id: 191610:CATYP_RS01460
uniprot id: A0A075TTP9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

191610:CATYP RS09990
gene id: 191610:CATYP_RS09990
uniprot id: A0A075TTH1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS04040
gene id: 191610:CATYP_RS04040
uniprot id: A0A075U1K8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

191610:CATYP RS01120
gene id: 191610:CATYP_RS01120
uniprot id: A0A075U0B3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

191610:CATYP RS06615
gene id: 191610:CATYP_RS06615
uniprot id: A0A075TS43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

191610:CATYP RS01325
gene id: 191610:CATYP_RS01325
uniprot id: A0A075TQ32
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

191610:CATYP RS00935
gene id: 191610:CATYP_RS00935
uniprot id: A0A075U084
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS07105
gene id: 191610:CATYP_RS07105
uniprot id: A0A075TWR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

191610:CATYP RS07485
gene id: 191610:CATYP_RS07485
uniprot id: A0A075TSG3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

191610:CATYP RS06775
gene id: 191610:CATYP_RS06775
uniprot id: A0A075TS63
names: Cofactor
messages: Can also use Mn(2+) ion.

191610:CATYP RS08880
gene id: 191610:CATYP_RS08880
uniprot id: A0A075TWT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

191610:CATYP RS04035
gene id: 191610:CATYP_RS04035
uniprot id: A0A075TUR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

191610:CATYP RS02150
gene id: 191610:CATYP_RS02150
uniprot id: A0A075TUL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

191610:CATYP RS01590
gene id: 191610:CATYP_RS01590
uniprot id: A0A075TQ65
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

191610:CATYP RS09550
gene id: 191610:CATYP_RS09550
uniprot id: A0A075U3T4
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

191610:CATYP RS05375
gene id: 191610:CATYP_RS05375
uniprot id: A0A075TV85
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS02950
gene id: 191610:CATYP_RS02950
uniprot id: A0A075TUY9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

191610:CATYP RS07115
gene id: 191610:CATYP_RS07115
uniprot id: A0A075TSB4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

191610:CATYP RS07490
gene id: 191610:CATYP_RS07490
uniprot id: A0A075TW67
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

191610:CATYP RS07510
gene id: 191610:CATYP_RS07510
uniprot id: A0A075U307
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

191610:CATYP RS05155
gene id: 191610:CATYP_RS05155
uniprot id: A0A075TV54
names: Caution
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS05870
gene id: 191610:CATYP_RS05870
uniprot id: A0A075TVG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

191610:CATYP RS08630
gene id: 191610:CATYP_RS08630
uniprot id: A0A075TWL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

191610:CATYP RS04700
gene id: 191610:CATYP_RS04700
uniprot id: A0A075TVM8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

191610:CATYP RS02445
gene id: 191610:CATYP_RS02445
uniprot id: A0A075TUP9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

191610:CATYP RS05070
gene id: 191610:CATYP_RS05070
uniprot id: A0A075U202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS00690
gene id: 191610:CATYP_RS00690
uniprot id: A0A075TPW7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

191610:CATYP RS06170
gene id: 191610:CATYP_RS06170
uniprot id: A0A075TVK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

191610:CATYP RS10400
gene id: 191610:CATYP_RS10400
uniprot id: A0A075U3S6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

191610:CATYP RS07320
gene id: 191610:CATYP_RS07320
uniprot id: A0A075U2X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

191610:CATYP RS04885
gene id: 191610:CATYP_RS04885
uniprot id: A0A075TRI4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

191610:CATYP RS05600
gene id: 191610:CATYP_RS05600
uniprot id: A0A075TVB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

191610:CATYP RS10355
gene id: 191610:CATYP_RS10355
uniprot id: A0A075TWZ0
names: Similarity
messages: Belongs to the peptidase S14 family.

191610:CATYP RS05130
gene id: 191610:CATYP_RS05130
uniprot id: A0A075TV55
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

191610:CATYP RS03230
gene id: 191610:CATYP_RS03230
uniprot id: A0A075TV18
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

191610:CATYP RS04045
gene id: 191610:CATYP_RS04045
uniprot id: A0A075TVE6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

191610:CATYP RS07670
gene id: 191610:CATYP_RS07670
uniprot id: A0A075TWE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

191610:CATYP RS06255
gene id: 191610:CATYP_RS06255
uniprot id: A0A075TVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

191610:CATYP RS02065
gene id: 191610:CATYP_RS02065
uniprot id: A0A075TTX9
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS09855
gene id: 191610:CATYP_RS09855
uniprot id: A0A075TY03
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

191610:CATYP RS02145
gene id: 191610:CATYP_RS02145
uniprot id: A0A075U0T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

191610:CATYP RS06085
gene id: 191610:CATYP_RS06085
uniprot id: A0A075TRY4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

191610:CATYP RS06275
gene id: 191610:CATYP_RS06275
uniprot id: A0A075TVM5
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS08500
gene id: 191610:CATYP_RS08500
uniprot id: A0A075TSV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS01925
gene id: 191610:CATYP_RS01925
uniprot id: A0A075TUI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

191610:CATYP RS07255
gene id: 191610:CATYP_RS07255
uniprot id: A0A075TW36
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

191610:CATYP RS08800
gene id: 191610:CATYP_RS08800
uniprot id: A0A075TSZ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

191610:CATYP RS07325
gene id: 191610:CATYP_RS07325
uniprot id: A0A075TWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

191610:CATYP RS03205
gene id: 191610:CATYP_RS03205
uniprot id: A0A075TQV5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

191610:CATYP RS03835
gene id: 191610:CATYP_RS03835
uniprot id: A0A075TVB5
names: Similarity
messages: Belongs to the P(II) protein family.

191610:CATYP RS09985
gene id: 191610:CATYP_RS09985
uniprot id: A0A075TY26
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

191610:CATYP RS02390
gene id: 191610:CATYP_RS02390
uniprot id: A0A075TQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

191610:CATYP RS07350
gene id: 191610:CATYP_RS07350
uniprot id: A0A075U2Y3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

191610:CATYP RS02725
gene id: 191610:CATYP_RS02725
uniprot id: A0A075TU96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

191610:CATYP RS10220
gene id: 191610:CATYP_RS10220
uniprot id: A0A075U441
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

191610:CATYP RS04865
gene id: 191610:CATYP_RS04865
uniprot id: A0A075TV19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

191610:CATYP RS03905
gene id: 191610:CATYP_RS03905
uniprot id: A0A075TVC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

191610:CATYP RS00110
gene id: 191610:CATYP_RS00110
uniprot id: A0A075TT24
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

191610:CATYP RS05700
gene id: 191610:CATYP_RS05700
uniprot id: A0A075TVE5
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS02675
gene id: 191610:CATYP_RS02675
uniprot id: A0A075U100
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

191610:CATYP RS00085
gene id: 191610:CATYP_RS00085
uniprot id: A0A075TTR6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

191610:CATYP RS09155
gene id: 191610:CATYP_RS09155
uniprot id: A0A075U3P6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

191610:CATYP RS04160
gene id: 191610:CATYP_RS04160
uniprot id: A0A075U1M5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS06825
gene id: 191610:CATYP_RS06825
uniprot id: A0A075U2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

191610:CATYP RS02100
gene id: 191610:CATYP_RS02100
uniprot id: A0A075TUK4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

191610:CATYP RS03140
gene id: 191610:CATYP_RS03140
uniprot id: A0A075TUG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS07980
gene id: 191610:CATYP_RS07980
uniprot id: A0A075TX48
names: Similarity
messages: Belongs to the heat shock protein 70 family.

191610:CATYP RS04270
gene id: 191610:CATYP_RS04270
uniprot id: A0A075TVH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS07315
gene id: 191610:CATYP_RS07315
uniprot id: A0A075TW96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS07165
gene id: 191610:CATYP_RS07165
uniprot id: A0A075TWS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS01820
gene id: 191610:CATYP_RS01820
uniprot id: A0A075TUG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

191610:CATYP RS06290
gene id: 191610:CATYP_RS06290
uniprot id: A0A075TWB1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

191610:CATYP RS09675
gene id: 191610:CATYP_RS09675
uniprot id: A0A075TX38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

191610:CATYP RS06235
gene id: 191610:CATYP_RS06235
uniprot id: A0A075U2F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

191610:CATYP RS09145
gene id: 191610:CATYP_RS09145
uniprot id: A0A075TWT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

191610:CATYP RS05960
gene id: 191610:CATYP_RS05960
uniprot id: A0A075TW56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

191610:CATYP RS05875
gene id: 191610:CATYP_RS05875
uniprot id: A0A075TVH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

191610:CATYP RS07590
gene id: 191610:CATYP_RS07590
uniprot id: A0A075TW81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

191610:CATYP RS06230
gene id: 191610:CATYP_RS06230
uniprot id: A0A075TVM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

191610:CATYP RS05165
gene id: 191610:CATYP_RS05165
uniprot id: A0A075U217
names: Similarity
messages: Belongs to the peptidase M18 family.

191610:CATYP RS03460
gene id: 191610:CATYP_RS03460
uniprot id: A0A075U1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

191610:CATYP RS05830
gene id: 191610:CATYP_RS05830
uniprot id: A0A075TRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

191610:CATYP RS01715
gene id: 191610:CATYP_RS01715
uniprot id: A0A075TTS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS10060
gene id: 191610:CATYP_RS10060
uniprot id: A0A075TX91
names: Similarity
messages: Belongs to the FPG family.

191610:CATYP RS00400
gene id: 191610:CATYP_RS00400
uniprot id: A0A075TT98
names: Similarity
messages: Belongs to the peptidase M13 family.

191610:CATYP RS02320
gene id: 191610:CATYP_RS02320
uniprot id: A0A075TUN0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

191610:CATYP RS08150
gene id: 191610:CATYP_RS08150
uniprot id: A0A075TWI6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

191610:CATYP RS05785
gene id: 191610:CATYP_RS05785
uniprot id: A0A075U2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

191610:CATYP RS06010
gene id: 191610:CATYP_RS06010
uniprot id: A0A075TVI8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS09850
gene id: 191610:CATYP_RS09850
uniprot id: A0A075U3W8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS04975
gene id: 191610:CATYP_RS04975
uniprot id: A0A075TVR4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

191610:CATYP RS06285
gene id: 191610:CATYP_RS06285
uniprot id: A0A075U2G6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

191610:CATYP RS02760
gene id: 191610:CATYP_RS02760
uniprot id: A0A075U110
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

191610:CATYP RS06795
gene id: 191610:CATYP_RS06795
uniprot id: A0A075U2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS07390
gene id: 191610:CATYP_RS07390
uniprot id: A0A075TWV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

191610:CATYP RS05435
gene id: 191610:CATYP_RS05435
uniprot id: A0A075TRQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

191610:CATYP RS02955
gene id: 191610:CATYP_RS02955
uniprot id: A0A075TQS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

191610:CATYP RS05720
gene id: 191610:CATYP_RS05720
uniprot id: A0A075TVD9
names: Similarity
messages: Belongs to the universal stress protein A family.

191610:CATYP RS00135
gene id: 191610:CATYP_RS00135
uniprot id: A0A075TTE2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

191610:CATYP RS07140
gene id: 191610:CATYP_RS07140
uniprot id: A0A075TSB9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

191610:CATYP RS06945
gene id: 191610:CATYP_RS06945
uniprot id: A0A075TW03
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

191610:CATYP RS05185
gene id: 191610:CATYP_RS05185
uniprot id: A0A075TV63
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

191610:CATYP RS08515
gene id: 191610:CATYP_RS08515
uniprot id: A0A075U3F9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

191610:CATYP RS10075
gene id: 191610:CATYP_RS10075
uniprot id: A0A075U417
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

191610:CATYP RS07855
gene id: 191610:CATYP_RS07855
uniprot id: A0A075TWF5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

191610:CATYP RS01530
gene id: 191610:CATYP_RS01530
uniprot id: A0A075TUC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

191610:CATYP RS07890
gene id: 191610:CATYP_RS07890
uniprot id: A0A075U356
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

191610:CATYP RS01950
gene id: 191610:CATYP_RS01950
uniprot id: A0A075TUI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

191610:CATYP RS07950
gene id: 191610:CATYP_RS07950
uniprot id: A0A075U363
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

191610:CATYP RS03755
gene id: 191610:CATYP_RS03755
uniprot id: A0A075TUQ2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

191610:CATYP RS02635
gene id: 191610:CATYP_RS02635
uniprot id: A0A075TQM7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

191610:CATYP RS06220
gene id: 191610:CATYP_RS06220
uniprot id: A0A075TRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

191610:CATYP RS04050
gene id: 191610:CATYP_RS04050
uniprot id: A0A075TR80
names: Similarity
messages: Belongs to the MQO family.

191610:CATYP RS07180
gene id: 191610:CATYP_RS07180
uniprot id: A0A075TW28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

191610:CATYP RS02430
gene id: 191610:CATYP_RS02430
uniprot id: A0A075TU34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

191610:CATYP RS04685
gene id: 191610:CATYP_RS04685
uniprot id: A0A075TUZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS04565
gene id: 191610:CATYP_RS04565
uniprot id: A0A075TRE9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

191610:CATYP RS03900
gene id: 191610:CATYP_RS03900
uniprot id: A0A075U1I4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

191610:CATYP RS07810
gene id: 191610:CATYP_RS07810
uniprot id: A0A075TSK7
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS08840
gene id: 191610:CATYP_RS08840
uniprot id: A0A075TWT3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

191610:CATYP RS01870
gene id: 191610:CATYP_RS01870
uniprot id: A0A075TUH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

191610:CATYP RS02510
gene id: 191610:CATYP_RS02510
uniprot id: A0A075TUQ9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

191610:CATYP RS01930
gene id: 191610:CATYP_RS01930
uniprot id: A0A075TQB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

191610:CATYP RS01750
gene id: 191610:CATYP_RS01750
uniprot id: A0A075TQ88
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

191610:CATYP RS10225
gene id: 191610:CATYP_RS10225
uniprot id: A0A075TY87
names: Similarity
messages: Belongs to the thioredoxin family.

191610:CATYP RS01790
gene id: 191610:CATYP_RS01790
uniprot id: A0A075TUG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

191610:CATYP RS04030
gene id: 191610:CATYP_RS04030
uniprot id: A0A075TUU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

191610:CATYP RS02690
gene id: 191610:CATYP_RS02690
uniprot id: A0A075TU91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

191610:CATYP RS01675
gene id: 191610:CATYP_RS01675
uniprot id: A0A075TUE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

191610:CATYP RS07365
gene id: 191610:CATYP_RS07365
uniprot id: A0A075TSE4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

191610:CATYP RS03685
gene id: 191610:CATYP_RS03685
uniprot id: A0A075U1G0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

191610:CATYP RS04665
gene id: 191610:CATYP_RS04665
uniprot id: A0A075TRG1
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS05530
gene id: 191610:CATYP_RS05530
uniprot id: A0A075U276
names: Similarity
messages: Belongs to the TlyA family.

191610:CATYP RS08010
gene id: 191610:CATYP_RS08010
uniprot id: A0A075TX51
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

191610:CATYP RS07305
gene id: 191610:CATYP_RS07305
uniprot id: A0A075TSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

191610:CATYP RS02480
gene id: 191610:CATYP_RS02480
uniprot id: A0A075TQK6
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS04095
gene id: 191610:CATYP_RS04095
uniprot id: A0A075TUV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

191610:CATYP RS02245
gene id: 191610:CATYP_RS02245
uniprot id: A0A075TU05
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

191610:CATYP RS02050
gene id: 191610:CATYP_RS02050
uniprot id: A0A075TUJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

191610:CATYP RS02115
gene id: 191610:CATYP_RS02115
uniprot id: A0A075TTY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

191610:CATYP RS07595
gene id: 191610:CATYP_RS07595
uniprot id: A0A075TWD3
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

191610:CATYP RS06840
gene id: 191610:CATYP_RS06840
uniprot id: A0A075TS72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

191610:CATYP RS02810
gene id: 191610:CATYP_RS02810
uniprot id: A0A075TU88
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

191610:CATYP RS01245
gene id: 191610:CATYP_RS01245
uniprot id: A0A075TTM3
names: Similarity
messages: Belongs to the HsdR family.

191610:CATYP RS08110
gene id: 191610:CATYP_RS08110
uniprot id: A0A075TWI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS01565
gene id: 191610:CATYP_RS01565
uniprot id: A0A075TTQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

191610:CATYP RS08385
gene id: 191610:CATYP_RS08385
uniprot id: A0A075TST4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

191610:CATYP RS03975
gene id: 191610:CATYP_RS03975
uniprot id: A0A075TR71
names: Similarity
messages: Belongs to the DprA/Smf family.

191610:CATYP RS07710
gene id: 191610:CATYP_RS07710
uniprot id: A0A075TSJ6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

191610:CATYP RS03310
gene id: 191610:CATYP_RS03310
uniprot id: A0A075TUJ2
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS02920
gene id: 191610:CATYP_RS02920
uniprot id: A0A075TUY5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

191610:CATYP RS06025
gene id: 191610:CATYP_RS06025
uniprot id: A0A075TW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

191610:CATYP RS07310
gene id: 191610:CATYP_RS07310
uniprot id: A0A075TW44
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

191610:CATYP RS09255
gene id: 191610:CATYP_RS09255
uniprot id: A0A075TXM7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

191610:CATYP RS04325
gene id: 191610:CATYP_RS04325
uniprot id: A0A075U1Q2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

191610:CATYP RS03810
gene id: 191610:CATYP_RS03810
uniprot id: A0A075TVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS08650
gene id: 191610:CATYP_RS08650
uniprot id: A0A075TXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

191610:CATYP RS08725
gene id: 191610:CATYP_RS08725
uniprot id: A0A075TWM2
names: Similarity
messages: Belongs to the TPP enzyme family.

191610:CATYP RS03235
gene id: 191610:CATYP_RS03235
uniprot id: A0A075TQW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

191610:CATYP RS03170
gene id: 191610:CATYP_RS03170
uniprot id: A0A075TV08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

191610:CATYP RS10450
gene id: 191610:CATYP_RS10450
uniprot id: A0A075U3T4
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

191610:CATYP RS06875
gene id: 191610:CATYP_RS06875
uniprot id: A0A075TW08
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

191610:CATYP RS01800
gene id: 191610:CATYP_RS01800
uniprot id: A0A075TTT3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

191610:CATYP RS00045
gene id: 191610:CATYP_RS00045
uniprot id: A0A075TPM3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

191610:CATYP RS03185
gene id: 191610:CATYP_RS03185
uniprot id: A0A075TUH0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

191610:CATYP RS04170
gene id: 191610:CATYP_RS04170
uniprot id: A0A075TRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

191610:CATYP RS04900
gene id: 191610:CATYP_RS04900
uniprot id: A0A075U1X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

191610:CATYP RS10260
gene id: 191610:CATYP_RS10260
uniprot id: A0A075TTR1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

191610:CATYP RS02085
gene id: 191610:CATYP_RS02085
uniprot id: A0A075TTX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

191610:CATYP RS09340
gene id: 191610:CATYP_RS09340
uniprot id: A0A075TWX0
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

191610:CATYP RS03775
gene id: 191610:CATYP_RS03775
uniprot id: A0A075TVA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

191610:CATYP RS05085
gene id: 191610:CATYP_RS05085
uniprot id: A0A075TVS9
names: Similarity
messages: Belongs to the UPF0098 family.

191610:CATYP RS07680
gene id: 191610:CATYP_RS07680
uniprot id: A0A075TX08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

191610:CATYP RS01935
gene id: 191610:CATYP_RS01935
uniprot id: A0A075TTU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

191610:CATYP RS00715
gene id: 191610:CATYP_RS00715
uniprot id: A0A075TU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

191610:CATYP RS04745
gene id: 191610:CATYP_RS04745
uniprot id: A0A075TV02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

191610:CATYP RS08870
gene id: 191610:CATYP_RS08870
uniprot id: A0A075TWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

191610:CATYP RS02340
gene id: 191610:CATYP_RS02340
uniprot id: A0A075U0V6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

191610:CATYP RS07650
gene id: 191610:CATYP_RS07650
uniprot id: A0A075U329
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

191610:CATYP RS04945
gene id: 191610:CATYP_RS04945
uniprot id: A0A075TVQ9
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS04645
gene id: 191610:CATYP_RS04645
uniprot id: A0A075U1T8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

191610:CATYP RS09390
gene id: 191610:CATYP_RS09390
uniprot id: A0A075U3R4
names: Subcellular Location Annotation
messages: Membrane

191610:CATYP RS08895
gene id: 191610:CATYP_RS08895
uniprot id: A0A075TXG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

191610:CATYP RS04780
gene id: 191610:CATYP_RS04780
uniprot id: A0A075U1V3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

191610:CATYP RS08355
gene id: 191610:CATYP_RS08355
uniprot id: A0A075TSS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

191610:CATYP RS05735
gene id: 191610:CATYP_RS05735
uniprot id: A0A075TW20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

191610:CATYP RS01915
gene id: 191610:CATYP_RS01915
uniprot id: A0A075TTV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

191610:CATYP RS04855
gene id: 191610:CATYP_RS04855
uniprot id: A0A075TRI1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

191610:CATYP RS02170
gene id: 191610:CATYP_RS02170
uniprot id: A0A075U0T4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS02770
gene id: 191610:CATYP_RS02770
uniprot id: A0A075TQQ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

191610:CATYP RS03585
gene id: 191610:CATYP_RS03585
uniprot id: A0A075TR39
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS06325
gene id: 191610:CATYP_RS06325
uniprot id: A0A075TWB8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

191610:CATYP RS09060
gene id: 191610:CATYP_RS09060
uniprot id: A0A075TT22
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

191610:CATYP RS01125
gene id: 191610:CATYP_RS01125
uniprot id: A0A075TU56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

191610:CATYP RS04785
gene id: 191610:CATYP_RS04785
uniprot id: A0A075TVN7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS05025
gene id: 191610:CATYP_RS05025
uniprot id: A0A075TV40
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

191610:CATYP RS03820
gene id: 191610:CATYP_RS03820
uniprot id: A0A075TUR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

191610:CATYP RS03225
gene id: 191610:CATYP_RS03225
uniprot id: A0A075U163
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

191610:CATYP RS05605
gene id: 191610:CATYP_RS05605
uniprot id: A0A075TVC7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS04140
gene id: 191610:CATYP_RS04140
uniprot id: A0A075TR99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

191610:CATYP RS06265
gene id: 191610:CATYP_RS06265
uniprot id: A0A075TWA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

191610:CATYP RS01970
gene id: 191610:CATYP_RS01970
uniprot id: A0A075U0Q2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

191610:CATYP RS07825
gene id: 191610:CATYP_RS07825
uniprot id: A0A075U348
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Membrane

191610:CATYP RS05610
gene id: 191610:CATYP_RS05610
uniprot id: A0A075U286
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

191610:CATYP RS07935
gene id: 191610:CATYP_RS07935
uniprot id: A0A075TSM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

191610:CATYP RS03410
gene id: 191610:CATYP_RS03410
uniprot id: A0A075U192
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

191610:CATYP RS06545
gene id: 191610:CATYP_RS06545
uniprot id: A0A075TS40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

191610:CATYP RS01305
gene id: 191610:CATYP_RS01305
uniprot id: A0A075TTM4
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

191610:CATYP RS05935
gene id: 191610:CATYP_RS05935
uniprot id: A0A075TVH5
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

191610:CATYP RS02055
gene id: 191610:CATYP_RS02055
uniprot id: A0A075TQD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

191610:CATYP RS08965
gene id: 191610:CATYP_RS08965
uniprot id: A0A075TXH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

191610:CATYP RS01480
gene id: 191610:CATYP_RS01480
uniprot id: A0A075TTP2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

191610:CATYP RS01805
gene id: 191610:CATYP_RS01805
uniprot id: A0A075TTU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

191610:CATYP RS02860
gene id: 191610:CATYP_RS02860
uniprot id: A0A075TUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

191610:CATYP RS10235
gene id: 191610:CATYP_RS10235
uniprot id: A0A075TXG8
names: Similarity
messages: Belongs to the ParB family.

191610:CATYP RS03465
gene id: 191610:CATYP_RS03465
uniprot id: A0A075TV68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

191610:CATYP RS07845
gene id: 191610:CATYP_RS07845
uniprot id: A0A075TSL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

191610:CATYP RS06210
gene id: 191610:CATYP_RS06210
uniprot id: A0A075U2F6
names: Similarity
messages: Belongs to the UPF0045 family.

191610:CATYP RS03860
gene id: 191610:CATYP_RS03860
uniprot id: A0A075U1I0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

191610:CATYP RS06790
gene id: 191610:CATYP_RS06790
uniprot id: A0A075TVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

191610:CATYP RS08675
gene id: 191610:CATYP_RS08675
uniprot id: A0A075U3H9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

191610:CATYP RS03660
gene id: 191610:CATYP_RS03660
uniprot id: A0A075TUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.