1913577:LPB144 RS03990
gene id: 1913577:LPB144_RS03990
uniprot id: A0A1L3J396
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS03660
gene id: 1913577:LPB144_RS03660
uniprot id: A0A1L3J333
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1913577:LPB144 RS06710
gene id: 1913577:LPB144_RS06710
uniprot id: A0A1L3J4N2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1913577:LPB144 RS13340
gene id: 1913577:LPB144_RS13340
uniprot id: A0A1L3J831
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1913577:LPB144 RS12370
gene id: 1913577:LPB144_RS12370
uniprot id: A0A1L3J7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1913577:LPB144 RS10995
gene id: 1913577:LPB144_RS10995
uniprot id: A0A1L3J6Z2
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1913577:LPB144 RS07090
gene id: 1913577:LPB144_RS07090
uniprot id: A0A1L3J4V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1913577:LPB144 RS01745
gene id: 1913577:LPB144_RS01745
uniprot id: A0A1L3J261
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1913577:LPB144 RS02785
gene id: 1913577:LPB144_RS02785
uniprot id: A0A1L3J2P8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1913577:LPB144 RS08330
gene id: 1913577:LPB144_RS08330
uniprot id: A0A1L3J5I3
names: Similarity
messages: Belongs to the Skp family.

1913577:LPB144 RS12250
gene id: 1913577:LPB144_RS12250
uniprot id: A0A1L3J8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1913577:LPB144 RS10505
gene id: 1913577:LPB144_RS10505
uniprot id: A0A1L3J6K0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1913577:LPB144 RS04715
gene id: 1913577:LPB144_RS04715
uniprot id: A0A1L3J3M9
names: Similarity
messages: Belongs to the CarB family.

1913577:LPB144 RS09750
gene id: 1913577:LPB144_RS09750
uniprot id: A0A1L3J677
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS13170
gene id: 1913577:LPB144_RS13170
uniprot id: A0A1L3J828
names: Similarity
messages: Belongs to the peptidase S51 family.

1913577:LPB144 RS13330
gene id: 1913577:LPB144_RS13330
uniprot id: A0A1L3J830
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1913577:LPB144 RS11840
gene id: 1913577:LPB144_RS11840
uniprot id: A0A1L3J7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1913577:LPB144 RS10750
gene id: 1913577:LPB144_RS10750
uniprot id: A0A1L3J6R2
names: Similarity
messages: Belongs to the GARS family.

1913577:LPB144 RS09560
gene id: 1913577:LPB144_RS09560
uniprot id: A0A1L3J638
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1913577:LPB144 RS07845
gene id: 1913577:LPB144_RS07845
uniprot id: A0A1L3J576
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1913577:LPB144 RS10915
gene id: 1913577:LPB144_RS10915
uniprot id: A0A1L3J6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1913577:LPB144 RS03080
gene id: 1913577:LPB144_RS03080
uniprot id: A0A1L3J2S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1913577:LPB144 RS05235
gene id: 1913577:LPB144_RS05235
uniprot id: A0A1L3J3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS13550
gene id: 1913577:LPB144_RS13550
uniprot id: A0A1L3J198
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1913577:LPB144 RS07860
gene id: 1913577:LPB144_RS07860
uniprot id: A0A1L3J573
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1913577:LPB144 RS00490
gene id: 1913577:LPB144_RS00490
uniprot id: A0A1L3J1H5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1913577:LPB144 RS12855
gene id: 1913577:LPB144_RS12855
uniprot id: A0A1L3J7T3
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1913577:LPB144 RS02525
gene id: 1913577:LPB144_RS02525
uniprot id: A0A1L3J2J6
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS13280
gene id: 1913577:LPB144_RS13280
uniprot id: A0A1L3J820
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1913577:LPB144 RS06635
gene id: 1913577:LPB144_RS06635
uniprot id: A0A1L3J4N3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1913577:LPB144 RS03410
gene id: 1913577:LPB144_RS03410
uniprot id: A0A1L3J2X9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1913577:LPB144 RS12725
gene id: 1913577:LPB144_RS12725
uniprot id: A0A1L3J7Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1913577:LPB144 RS04375
gene id: 1913577:LPB144_RS04375
uniprot id: A0A1L3J3E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS00930
gene id: 1913577:LPB144_RS00930
uniprot id: A0A1L3J1N2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1913577:LPB144 RS05195
gene id: 1913577:LPB144_RS05195
uniprot id: A0A1L3J3V8
names: Similarity
messages: Belongs to the peptidase M1 family.

1913577:LPB144 RS04205
gene id: 1913577:LPB144_RS04205
uniprot id: A0A1L3J3D0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1913577:LPB144 RS09830
gene id: 1913577:LPB144_RS09830
uniprot id: A0A1L3J689
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1913577:LPB144 RS08645
gene id: 1913577:LPB144_RS08645
uniprot id: A0A1L3J5K6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1913577:LPB144 RS03775
gene id: 1913577:LPB144_RS03775
uniprot id: A0A1L3J352
names: Similarity
messages: Belongs to the SUI1 family.

1913577:LPB144 RS07890
gene id: 1913577:LPB144_RS07890
uniprot id: A0A1L3J5C0
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS11155
gene id: 1913577:LPB144_RS11155
uniprot id: A0A1L3J6X0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1913577:LPB144 RS01475
gene id: 1913577:LPB144_RS01475
uniprot id: A0A1L3J1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1913577:LPB144 RS03665
gene id: 1913577:LPB144_RS03665
uniprot id: A0A1L3J8A1
names: Similarity
messages: Belongs to the RutC family.

1913577:LPB144 RS04670
gene id: 1913577:LPB144_RS04670
uniprot id: A0A1L3J3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS11410
gene id: 1913577:LPB144_RS11410
uniprot id: A0A1L3J754
names: Similarity
messages: Belongs to the SufE family.

1913577:LPB144 RS02760
gene id: 1913577:LPB144_RS02760
uniprot id: A0A1L3J2P3
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS13205
gene id: 1913577:LPB144_RS13205
uniprot id: A0A1L3J829
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10005
gene id: 1913577:LPB144_RS10005
uniprot id: A0A1L3J6C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1913577:LPB144 RS11500
gene id: 1913577:LPB144_RS11500
uniprot id: A0A1L3J749
names: Similarity
messages: Belongs to the UPF0102 family.

1913577:LPB144 RS06070
gene id: 1913577:LPB144_RS06070
uniprot id: A0A1L3J4A3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913577:LPB144 RS06270
gene id: 1913577:LPB144_RS06270
uniprot id: A0A1L3J4G1
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS04380
gene id: 1913577:LPB144_RS04380
uniprot id: A0A1L3J3G1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1913577:LPB144 RS00300
gene id: 1913577:LPB144_RS00300
uniprot id: A0A1L3J864
names: Similarity
messages: Belongs to the HSP15 family.

1913577:LPB144 RS01455
gene id: 1913577:LPB144_RS01455
uniprot id: A0A1L3J204
names: Similarity
messages: Belongs to the nitroreductase family.

1913577:LPB144 RS13450
gene id: 1913577:LPB144_RS13450
uniprot id: A0A1L3J842
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS07360
gene id: 1913577:LPB144_RS07360
uniprot id: A0A1L3J4Y4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1913577:LPB144 RS07595
gene id: 1913577:LPB144_RS07595
uniprot id: A0A1L3J562
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1913577:LPB144 RS06565
gene id: 1913577:LPB144_RS06565
uniprot id: A0A1L3J4N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1913577:LPB144 RS07525
gene id: 1913577:LPB144_RS07525
uniprot id: A0A1L3J4Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS09855
gene id: 1913577:LPB144_RS09855
uniprot id: A0A1L3J6C5
names: Similarity
messages: Belongs to the peptidase S41A family.

1913577:LPB144 RS11765
gene id: 1913577:LPB144_RS11765
uniprot id: A0A1L3J8M9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1913577:LPB144 RS06780
gene id: 1913577:LPB144_RS06780
uniprot id: A0A1L3J4M4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1913577:LPB144 RS01855
gene id: 1913577:LPB144_RS01855
uniprot id: A0A1L3J269
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1913577:LPB144 RS01185
gene id: 1913577:LPB144_RS01185
uniprot id: A0A1L3J1V5
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS11240
gene id: 1913577:LPB144_RS11240
uniprot id: A0A1L3J708
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1913577:LPB144 RS11085
gene id: 1913577:LPB144_RS11085
uniprot id: A0A1L3J6Z9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS06140
gene id: 1913577:LPB144_RS06140
uniprot id: A0A1L3J4E8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1913577:LPB144 RS07365
gene id: 1913577:LPB144_RS07365
uniprot id: A0A1L3J4X0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1913577:LPB144 RS03295
gene id: 1913577:LPB144_RS03295
uniprot id: A0A1L3J2V8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS10975
gene id: 1913577:LPB144_RS10975
uniprot id: A0A1L3J6W4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1913577:LPB144 RS13090
gene id: 1913577:LPB144_RS13090
uniprot id: A0A1L3J7Z3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1913577:LPB144 RS08905
gene id: 1913577:LPB144_RS08905
uniprot id: A0A1L3J5R1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS04505
gene id: 1913577:LPB144_RS04505
uniprot id: A0A1L3J3H0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1913577:LPB144 RS06575
gene id: 1913577:LPB144_RS06575
uniprot id: A0A1L3J4K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1913577:LPB144 RS12675
gene id: 1913577:LPB144_RS12675
uniprot id: A0A1L3J7N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1913577:LPB144 RS01565
gene id: 1913577:LPB144_RS01565
uniprot id: A0A1L3J220
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1913577:LPB144 RS10465
gene id: 1913577:LPB144_RS10465
uniprot id: A0A1L3J6K8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1913577:LPB144 RS13055
gene id: 1913577:LPB144_RS13055
uniprot id: A0A1L3J801
names: Similarity
messages: Belongs to the peptidase S66 family.

1913577:LPB144 RS09435
gene id: 1913577:LPB144_RS09435
uniprot id: A0A1L3J622
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1913577:LPB144 RS10475
gene id: 1913577:LPB144_RS10475
uniprot id: A0A1L3J6N1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1913577:LPB144 RS00250
gene id: 1913577:LPB144_RS00250
uniprot id: A0A1L3J1D9
names: Similarity
messages: Belongs to the sterol desaturase family.

1913577:LPB144 RS10305
gene id: 1913577:LPB144_RS10305
uniprot id: A0A1L3J6K5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS07855
gene id: 1913577:LPB144_RS07855
uniprot id: A0A1L3J574
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1913577:LPB144 RS08535
gene id: 1913577:LPB144_RS08535
uniprot id: A0A1L3J5N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1913577:LPB144 RS02720
gene id: 1913577:LPB144_RS02720
uniprot id: A0A1L3J2N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1913577:LPB144 RS08400
gene id: 1913577:LPB144_RS08400
uniprot id: A0A1L3J5H7
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS02275
gene id: 1913577:LPB144_RS02275
uniprot id: A0A1L3J2F7
names: Similarity
messages: Belongs to the threonine synthase family.

1913577:LPB144 RS02210
gene id: 1913577:LPB144_RS02210
uniprot id: A0A1L3J2E8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1913577:LPB144 RS10875
gene id: 1913577:LPB144_RS10875
uniprot id: A0A1L3J6V4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1913577:LPB144 RS00795
gene id: 1913577:LPB144_RS00795
uniprot id: A0A1L3J1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1913577:LPB144 RS07535
gene id: 1913577:LPB144_RS07535
uniprot id: A0A1L3J538
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1913577:LPB144 RS07135
gene id: 1913577:LPB144_RS07135
uniprot id: A0A1L3J4X9
names: Similarity
messages: Belongs to the P(II) protein family.

1913577:LPB144 RS05965
gene id: 1913577:LPB144_RS05965
uniprot id: A0A1L3J4A9
names: Similarity
messages: Belongs to the BshC family.

1913577:LPB144 RS08490
gene id: 1913577:LPB144_RS08490
uniprot id: A0A1L3J5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1913577:LPB144 RS08410
gene id: 1913577:LPB144_RS08410
uniprot id: A0A1L3J5H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS09345
gene id: 1913577:LPB144_RS09345
uniprot id: A0A1L3J625
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1913577:LPB144 RS11430
gene id: 1913577:LPB144_RS11430
uniprot id: A0A1L3J767
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1913577:LPB144 RS08065
gene id: 1913577:LPB144_RS08065
uniprot id: A0A1L3J5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1913577:LPB144 RS11190
gene id: 1913577:LPB144_RS11190
uniprot id: A0A1L3J701
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1913577:LPB144 RS10695
gene id: 1913577:LPB144_RS10695
uniprot id: A0A1L3J6N8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1913577:LPB144 RS04510
gene id: 1913577:LPB144_RS04510
uniprot id: A0A1L3J3J8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1913577:LPB144 RS12495
gene id: 1913577:LPB144_RS12495
uniprot id: A0A1L3J7L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1913577:LPB144 RS01930
gene id: 1913577:LPB144_RS01930
uniprot id: A0A1L3J2A4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS12800
gene id: 1913577:LPB144_RS12800
uniprot id: A0A1L3J7S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1913577:LPB144 RS01405
gene id: 1913577:LPB144_RS01405
uniprot id: A0A1L3J1Z4
names: Similarity
messages: Belongs to the AHA1 family.

1913577:LPB144 RS07205
gene id: 1913577:LPB144_RS07205
uniprot id: A0A1L3J500
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1913577:LPB144 RS13430
gene id: 1913577:LPB144_RS13430
uniprot id: A0A1L3J877
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1913577:LPB144 RS04085
gene id: 1913577:LPB144_RS04085
uniprot id: A0A1L3J3B4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1913577:LPB144 RS12535
gene id: 1913577:LPB144_RS12535
uniprot id: A0A1L3J7R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1913577:LPB144 RS07020
gene id: 1913577:LPB144_RS07020
uniprot id: A0A1L3J8E7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1913577:LPB144 RS00050
gene id: 1913577:LPB144_RS00050
uniprot id: A0A1L3J198
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1913577:LPB144 RS13110
gene id: 1913577:LPB144_RS13110
uniprot id: A0A1L3J817
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1913577:LPB144 RS13360
gene id: 1913577:LPB144_RS13360
uniprot id: A0A1L3J852
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1913577:LPB144 RS12570
gene id: 1913577:LPB144_RS12570
uniprot id: A0A1L3J7Q7
names: Similarity
messages: Belongs to the UPF0758 family.

1913577:LPB144 RS03240
gene id: 1913577:LPB144_RS03240
uniprot id: A0A1L3J2U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1913577:LPB144 RS10705
gene id: 1913577:LPB144_RS10705
uniprot id: A0A1L3J6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1913577:LPB144 RS10940
gene id: 1913577:LPB144_RS10940
uniprot id: A0A1L3J6T0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1913577:LPB144 RS09850
gene id: 1913577:LPB144_RS09850
uniprot id: A0A1L3J680
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1913577:LPB144 RS06230
gene id: 1913577:LPB144_RS06230
uniprot id: A0A1L3J4E0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1913577:LPB144 RS11960
gene id: 1913577:LPB144_RS11960
uniprot id: A0A1L3J7C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1913577:LPB144 RS12995
gene id: 1913577:LPB144_RS12995
uniprot id: A0A1L3J7Z1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10245
gene id: 1913577:LPB144_RS10245
uniprot id: A0A1L3J6G3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

1913577:LPB144 RS06110
gene id: 1913577:LPB144_RS06110
uniprot id: A0A1L3J4E7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1913577:LPB144 RS08160
gene id: 1913577:LPB144_RS08160
uniprot id: A0A1L3J8J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1913577:LPB144 RS13410
gene id: 1913577:LPB144_RS13410
uniprot id: A0A1L3J8M8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1913577:LPB144 RS03970
gene id: 1913577:LPB144_RS03970
uniprot id: A0A1L3J397
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS01250
gene id: 1913577:LPB144_RS01250
uniprot id: A0A1L3J1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1913577:LPB144 RS01830
gene id: 1913577:LPB144_RS01830
uniprot id: A0A1L3J888
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1913577:LPB144 RS08790
gene id: 1913577:LPB144_RS08790
uniprot id: A0A1L3J5P0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS01325
gene id: 1913577:LPB144_RS01325
uniprot id: A0A1L3J1X8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1913577:LPB144 RS12750
gene id: 1913577:LPB144_RS12750
uniprot id: A0A1L3J7R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1913577:LPB144 RS07045
gene id: 1913577:LPB144_RS07045
uniprot id: A0A1L3J4T6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1913577:LPB144 RS01085
gene id: 1913577:LPB144_RS01085
uniprot id: A0A1L3J1T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1913577:LPB144 RS03065
gene id: 1913577:LPB144_RS03065
uniprot id: A0A1L3J2R2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1913577:LPB144 RS08250
gene id: 1913577:LPB144_RS08250
uniprot id: A0A1L3J5E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1913577:LPB144 RS10150
gene id: 1913577:LPB144_RS10150
uniprot id: A0A1L3J8M0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1913577:LPB144 RS02370
gene id: 1913577:LPB144_RS02370
uniprot id: A0A1L3J2H2
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS09635
gene id: 1913577:LPB144_RS09635
uniprot id: A0A1L3J639
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS00495
gene id: 1913577:LPB144_RS00495
uniprot id: A0A1L3J1H6
names: Similarity
messages: Belongs to the IMPACT family.

1913577:LPB144 RS10850
gene id: 1913577:LPB144_RS10850
uniprot id: A0A1L3J6Q4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1913577:LPB144 RS03355
gene id: 1913577:LPB144_RS03355
uniprot id: A0A1L3J2X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1913577:LPB144 RS00575
gene id: 1913577:LPB144_RS00575
uniprot id: A0A1L3J1J5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS11125
gene id: 1913577:LPB144_RS11125
uniprot id: A0A1L3J6X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1913577:LPB144 RS08390
gene id: 1913577:LPB144_RS08390
uniprot id: A0A1L3J5J0
names: Similarity
messages: Belongs to the SCO1/2 family.

1913577:LPB144 RS03835
gene id: 1913577:LPB144_RS03835
uniprot id: A0A1L3J346
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1913577:LPB144 RS08495
gene id: 1913577:LPB144_RS08495
uniprot id: A0A1L3J5L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1913577:LPB144 RS06625
gene id: 1913577:LPB144_RS06625
uniprot id: A0A1L3J4M8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913577:LPB144 RS09430
gene id: 1913577:LPB144_RS09430
uniprot id: A0A1L3J8L1
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS04150
gene id: 1913577:LPB144_RS04150
uniprot id: A0A1L3J3B3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1913577:LPB144 RS10570
gene id: 1913577:LPB144_RS10570
uniprot id: A0A1L3J6M3
names: Similarity
messages: Belongs to the peptidase S8 family.

1913577:LPB144 RS00590
gene id: 1913577:LPB144_RS00590
uniprot id: A0A1L3J1J2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1913577:LPB144 RS01800
gene id: 1913577:LPB144_RS01800
uniprot id: A0A1L3J259
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1913577:LPB144 RS02360
gene id: 1913577:LPB144_RS02360
uniprot id: A0A1L3J2G0
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS11740
gene id: 1913577:LPB144_RS11740
uniprot id: A0A1L3J7A1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS08775
gene id: 1913577:LPB144_RS08775
uniprot id: A0A1L3J5R3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913577:LPB144 RS08020
gene id: 1913577:LPB144_RS08020
uniprot id: A0A1L3J591
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1913577:LPB144 RS12740
gene id: 1913577:LPB144_RS12740
uniprot id: A0A1L3J7R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1913577:LPB144 RS00140
gene id: 1913577:LPB144_RS00140
uniprot id: A0A1L3J1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1913577:LPB144 RS09765
gene id: 1913577:LPB144_RS09765
uniprot id: A0A1L3J6A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1913577:LPB144 RS08975
gene id: 1913577:LPB144_RS08975
uniprot id: A0A1L3J5R6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1913577:LPB144 RS10395
gene id: 1913577:LPB144_RS10395
uniprot id: A0A1L3J6I0
names: Similarity
messages: Belongs to the RecJ family.

1913577:LPB144 RS06820
gene id: 1913577:LPB144_RS06820
uniprot id: A0A1L3J4P7
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

1913577:LPB144 RS02300
gene id: 1913577:LPB144_RS02300
uniprot id: A0A1L3J2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1913577:LPB144 RS03640
gene id: 1913577:LPB144_RS03640
uniprot id: A0A1L3J320
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1913577:LPB144 RS03315
gene id: 1913577:LPB144_RS03315
uniprot id: A0A1L3J2W1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1913577:LPB144 RS02270
gene id: 1913577:LPB144_RS02270
uniprot id: A0A1L3J2F4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS01580
gene id: 1913577:LPB144_RS01580
uniprot id: A0A1L3J205
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1913577:LPB144 RS12715
gene id: 1913577:LPB144_RS12715
uniprot id: A0A1L3J7T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1913577:LPB144 RS09535
gene id: 1913577:LPB144_RS09535
uniprot id: A0A1L3J670
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS02150
gene id: 1913577:LPB144_RS02150
uniprot id: A0A1L3J2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1913577:LPB144 RS08910
gene id: 1913577:LPB144_RS08910
uniprot id: A0A1L3J5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1913577:LPB144 RS07480
gene id: 1913577:LPB144_RS07480
uniprot id: A0A1L3J524
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1913577:LPB144 RS12685
gene id: 1913577:LPB144_RS12685
uniprot id: A0A1L3J7T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1913577:LPB144 RS06500
gene id: 1913577:LPB144_RS06500
uniprot id: A0A1L3J4J9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1913577:LPB144 RS06105
gene id: 1913577:LPB144_RS06105
uniprot id: A0A1L3J4E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1913577:LPB144 RS04220
gene id: 1913577:LPB144_RS04220
uniprot id: A0A1L3J3D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1913577:LPB144 RS01505
gene id: 1913577:LPB144_RS01505
uniprot id: A0A1L3J211
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS06035
gene id: 1913577:LPB144_RS06035
uniprot id: A0A1L3J4C8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1913577:LPB144 RS01170
gene id: 1913577:LPB144_RS01170
uniprot id: A0A1L3J1V0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1913577:LPB144 RS03760
gene id: 1913577:LPB144_RS03760
uniprot id: A0A1L3J364
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1913577:LPB144 RS06505
gene id: 1913577:LPB144_RS06505
uniprot id: A0A1L3J4L4
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1913577:LPB144 RS08035
gene id: 1913577:LPB144_RS08035
uniprot id: A0A1L3J5E3
names: Similarity
messages: Belongs to the fabD family.

1913577:LPB144 RS12280
gene id: 1913577:LPB144_RS12280
uniprot id: A0A1L3J7L8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1913577:LPB144 RS13030
gene id: 1913577:LPB144_RS13030
uniprot id: A0A1L3J7X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1913577:LPB144 RS04235
gene id: 1913577:LPB144_RS04235
uniprot id: A0A1L3J3C3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1913577:LPB144 RS07215
gene id: 1913577:LPB144_RS07215
uniprot id: A0A1L3J8E8
names: Similarity
messages: Belongs to the AIR synthase family.

1913577:LPB144 RS08435
gene id: 1913577:LPB144_RS08435
uniprot id: A0A1L3J5K0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1913577:LPB144 RS02455
gene id: 1913577:LPB144_RS02455
uniprot id: A0A1L3J2J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1913577:LPB144 RS08545
gene id: 1913577:LPB144_RS08545
uniprot id: A0A1L3J5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1913577:LPB144 RS12105
gene id: 1913577:LPB144_RS12105
uniprot id: A0A1L3J7J3
names: Similarity
messages: Belongs to the peptidase C40 family.

1913577:LPB144 RS01655
gene id: 1913577:LPB144_RS01655
uniprot id: A0A1L3J242
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS01465
gene id: 1913577:LPB144_RS01465
uniprot id: A0A1L3J202
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS02320
gene id: 1913577:LPB144_RS02320
uniprot id: A0A1L3J2G4
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

1913577:LPB144 RS06380
gene id: 1913577:LPB144_RS06380
uniprot id: A0A1L3J4G7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1913577:LPB144 RS02835
gene id: 1913577:LPB144_RS02835
uniprot id: A0A1L3J2Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1913577:LPB144 RS05830
gene id: 1913577:LPB144_RS05830
uniprot id: A0A1L3J8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS10335
gene id: 1913577:LPB144_RS10335
uniprot id: A0A1L3J6G5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS04025
gene id: 1913577:LPB144_RS04025
uniprot id: A0A1L3J3A7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1913577:LPB144 RS10105
gene id: 1913577:LPB144_RS10105
uniprot id: A0A1L3J6D9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1913577:LPB144 RS07315
gene id: 1913577:LPB144_RS07315
uniprot id: A0A1L3J512
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1913577:LPB144 RS12355
gene id: 1913577:LPB144_RS12355
uniprot id: A0A1L3J7M2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913577:LPB144 RS11080
gene id: 1913577:LPB144_RS11080
uniprot id: A0A1L3J6Z4
names: Similarity
messages: Belongs to the DtxR/MntR family.

1913577:LPB144 RS12410
gene id: 1913577:LPB144_RS12410
uniprot id: A0A1L3J7M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1913577:LPB144 RS07300
gene id: 1913577:LPB144_RS07300
uniprot id: A0A1L3J508
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1913577:LPB144 RS13520
gene id: 1913577:LPB144_RS13520
uniprot id: A0A1L3J869
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS09340
gene id: 1913577:LPB144_RS09340
uniprot id: A0A1L3J613
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1913577:LPB144 RS05950
gene id: 1913577:LPB144_RS05950
uniprot id: A0A1L3J4B2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1913577:LPB144 RS08375
gene id: 1913577:LPB144_RS08375
uniprot id: A0A1L3J5I4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1913577:LPB144 RS08335
gene id: 1913577:LPB144_RS08335
uniprot id: A0A1L3J5J9
names: Similarity
messages: Belongs to the Skp family.

1913577:LPB144 RS04700
gene id: 1913577:LPB144_RS04700
uniprot id: A0A1L3J3L6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1913577:LPB144 RS00205
gene id: 1913577:LPB144_RS00205
uniprot id: A0A1L3J1C3
names: Similarity
messages: Belongs to the Skp family.

1913577:LPB144 RS08860
gene id: 1913577:LPB144_RS08860
uniprot id: A0A1L3J5S2
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1913577:LPB144 RS11845
gene id: 1913577:LPB144_RS11845
uniprot id: A0A1L3J7A2
names: Similarity
messages: Belongs to the arginase family.

1913577:LPB144 RS00340
gene id: 1913577:LPB144_RS00340
uniprot id: A0A1L3J1E1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1913577:LPB144 RS01975
gene id: 1913577:LPB144_RS01975
uniprot id: A0A1L3J299
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10470
gene id: 1913577:LPB144_RS10470
uniprot id: A0A1L3J6Q0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1913577:LPB144 RS12145
gene id: 1913577:LPB144_RS12145
uniprot id: A0A1L3J7I7
names: Similarity
messages: Belongs to the MreC family.

1913577:LPB144 RS04000
gene id: 1913577:LPB144_RS04000
uniprot id: A0A1L3J381
names: Similarity
messages: Belongs to the aspartokinase family.

1913577:LPB144 RS07495
gene id: 1913577:LPB144_RS07495
uniprot id: A0A1L3J544
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS10420
gene id: 1913577:LPB144_RS10420
uniprot id: A0A1L3J6M5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1913577:LPB144 RS05995
gene id: 1913577:LPB144_RS05995
uniprot id: A0A1L3J4B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1913577:LPB144 RS11995
gene id: 1913577:LPB144_RS11995
uniprot id: A0A1L3J7G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1913577:LPB144 RS07380
gene id: 1913577:LPB144_RS07380
uniprot id: A0A1L3J515
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1913577:LPB144 RS10145
gene id: 1913577:LPB144_RS10145
uniprot id: A0A1L3J6H2
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS04595
gene id: 1913577:LPB144_RS04595
uniprot id: A0A1L3J3J4
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS10055
gene id: 1913577:LPB144_RS10055
uniprot id: A0A1L3J6E4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1913577:LPB144 RS08800
gene id: 1913577:LPB144_RS08800
uniprot id: A0A1L3J8K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1913577:LPB144 RS06875
gene id: 1913577:LPB144_RS06875
uniprot id: A0A1L3J8E3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10435
gene id: 1913577:LPB144_RS10435
uniprot id: A0A1L3J6K4
names: Similarity
messages: Belongs to the peptidase S9A family.

1913577:LPB144 RS06530
gene id: 1913577:LPB144_RS06530
uniprot id: A0A1L3J4J8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1913577:LPB144 RS13285
gene id: 1913577:LPB144_RS13285
uniprot id: A0A1L3J811
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1913577:LPB144 RS01945
gene id: 1913577:LPB144_RS01945
uniprot id: A0A1L3J287
names: Similarity
messages: Belongs to the LOG family.

1913577:LPB144 RS04720
gene id: 1913577:LPB144_RS04720
uniprot id: A0A1L3J3L4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1913577:LPB144 RS02635
gene id: 1913577:LPB144_RS02635
uniprot id: A0A1L3J2M0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1913577:LPB144 RS06685
gene id: 1913577:LPB144_RS06685
uniprot id: A0A1L3J4P1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1913577:LPB144 RS10650
gene id: 1913577:LPB144_RS10650
uniprot id: A0A1L3J6P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913577:LPB144 RS10735
gene id: 1913577:LPB144_RS10735
uniprot id: A0A1L3J6U3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1913577:LPB144 RS02695
gene id: 1913577:LPB144_RS02695
uniprot id: A0A1L3J2N5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1913577:LPB144 RS06365
gene id: 1913577:LPB144_RS06365
uniprot id: A0A1L3J4H0
names: Similarity
messages: Belongs to the peptidase M1 family.

1913577:LPB144 RS12125
gene id: 1913577:LPB144_RS12125
uniprot id: A0A1L3J8M2
names: Similarity
messages: Belongs to the peptidase S41A family.

1913577:LPB144 RS03700
gene id: 1913577:LPB144_RS03700
uniprot id: A0A1L3J328
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1913577:LPB144 RS03815
gene id: 1913577:LPB144_RS03815
uniprot id: A0A1L3J8D2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1913577:LPB144 RS03980
gene id: 1913577:LPB144_RS03980
uniprot id: A0A1L3J393
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS08045
gene id: 1913577:LPB144_RS08045
uniprot id: A0A1L3J8H8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1913577:LPB144 RS01865
gene id: 1913577:LPB144_RS01865
uniprot id: A0A1L3J275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS12445
gene id: 1913577:LPB144_RS12445
uniprot id: A0A1L3J7K5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913577:LPB144 RS04335
gene id: 1913577:LPB144_RS04335
uniprot id: A0A1L3J3E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS06370
gene id: 1913577:LPB144_RS06370
uniprot id: A0A1L3J4I1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1913577:LPB144 RS07755
gene id: 1913577:LPB144_RS07755
uniprot id: A0A1L3J535
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1913577:LPB144 RS10675
gene id: 1913577:LPB144_RS10675
uniprot id: A0A1L3J6R0
names: Similarity
messages: Belongs to the Skp family.

1913577:LPB144 RS09515
gene id: 1913577:LPB144_RS09515
uniprot id: A0A1L3J643
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS08415
gene id: 1913577:LPB144_RS08415
uniprot id: A0A1L3J5H0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1913577:LPB144 RS11955
gene id: 1913577:LPB144_RS11955
uniprot id: A0A1L3J7C4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1913577:LPB144 RS06605
gene id: 1913577:LPB144_RS06605
uniprot id: A0A1L3J4K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1913577:LPB144 RS12885
gene id: 1913577:LPB144_RS12885
uniprot id: A0A1L3J7T1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1913577:LPB144 RS04810
gene id: 1913577:LPB144_RS04810
uniprot id: A0A1L3J3N3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10550
gene id: 1913577:LPB144_RS10550
uniprot id: A0A1L3J6L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1913577:LPB144 RS08290
gene id: 1913577:LPB144_RS08290
uniprot id: A0A1L3J5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1913577:LPB144 RS08070
gene id: 1913577:LPB144_RS08070
uniprot id: A0A1L3J5B3
names: Similarity
messages: Belongs to the Fur family.

1913577:LPB144 RS11405
gene id: 1913577:LPB144_RS11405
uniprot id: A0A1L3J743
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1913577:LPB144 RS07885
gene id: 1913577:LPB144_RS07885
uniprot id: A0A1L3J5A4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS05225
gene id: 1913577:LPB144_RS05225
uniprot id: A0A1L3J3V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1913577:LPB144 RS06515
gene id: 1913577:LPB144_RS06515
uniprot id: A0A1L3J4M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1913577:LPB144 RS12730
gene id: 1913577:LPB144_RS12730
uniprot id: A0A1L3J7U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1913577:LPB144 RS04570
gene id: 1913577:LPB144_RS04570
uniprot id: A0A1L3J3K9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1913577:LPB144 RS08735
gene id: 1913577:LPB144_RS08735
uniprot id: A0A1L3J5N1
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1913577:LPB144 RS05140
gene id: 1913577:LPB144_RS05140
uniprot id: A0A1L3J3U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1913577:LPB144 RS13165
gene id: 1913577:LPB144_RS13165
uniprot id: A0A1L3J823
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1913577:LPB144 RS13535
gene id: 1913577:LPB144_RS13535
uniprot id: A0A1L3J876
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1913577:LPB144 RS05360
gene id: 1913577:LPB144_RS05360
uniprot id: A0A1L3J412
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS11135
gene id: 1913577:LPB144_RS11135
uniprot id: A0A1L3J6Y5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1913577:LPB144 RS12965
gene id: 1913577:LPB144_RS12965
uniprot id: A0A1L3J7V3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1913577:LPB144 RS03400
gene id: 1913577:LPB144_RS03400
uniprot id: A0A1L3J2Z1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1913577:LPB144 RS09920
gene id: 1913577:LPB144_RS09920
uniprot id: A0A1L3J6B5
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1913577:LPB144 RS00510
gene id: 1913577:LPB144_RS00510
uniprot id: A0A1L3J1H3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1913577:LPB144 RS13415
gene id: 1913577:LPB144_RS13415
uniprot id: A0A1L3J855
names: Similarity
messages: Belongs to the UPF0246 family.

1913577:LPB144 RS07155
gene id: 1913577:LPB144_RS07155
uniprot id: A0A1L3J4W9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS13395
gene id: 1913577:LPB144_RS13395
uniprot id: A0A1L3J847
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1913577:LPB144 RS12660
gene id: 1913577:LPB144_RS12660
uniprot id: A0A1L3J7R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1913577:LPB144 RS09015
gene id: 1913577:LPB144_RS09015
uniprot id: A0A1L3J5V5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1913577:LPB144 RS04410
gene id: 1913577:LPB144_RS04410
uniprot id: A0A1L3J3H7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1913577:LPB144 RS11545
gene id: 1913577:LPB144_RS11545
uniprot id: A0A1L3J748
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS05980
gene id: 1913577:LPB144_RS05980
uniprot id: A0A1L3J481
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1913577:LPB144 RS05205
gene id: 1913577:LPB144_RS05205
uniprot id: A0A1L3J3Y4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1913577:LPB144 RS07140
gene id: 1913577:LPB144_RS07140
uniprot id: A0A1L3J4Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS13245
gene id: 1913577:LPB144_RS13245
uniprot id: A0A1L3J816
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1913577:LPB144 RS07425
gene id: 1913577:LPB144_RS07425
uniprot id: A0A1L3J526
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1913577:LPB144 RS08050
gene id: 1913577:LPB144_RS08050
uniprot id: A0A1L3J5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1913577:LPB144 RS06190
gene id: 1913577:LPB144_RS06190
uniprot id: A0A1L3J4F2
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS12110
gene id: 1913577:LPB144_RS12110
uniprot id: A0A1L3J7F7
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1913577:LPB144 RS08270
gene id: 1913577:LPB144_RS08270
uniprot id: A0A1L3J5G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1913577:LPB144 RS06145
gene id: 1913577:LPB144_RS06145
uniprot id: A0A1L3J4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1913577:LPB144 RS11175
gene id: 1913577:LPB144_RS11175
uniprot id: A0A1L3J6Y3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1913577:LPB144 RS12920
gene id: 1913577:LPB144_RS12920
uniprot id: A0A1L3J8P8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS07690
gene id: 1913577:LPB144_RS07690
uniprot id: A0A1L3J543
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1913577:LPB144 RS07025
gene id: 1913577:LPB144_RS07025
uniprot id: A0A1L3J4W6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1913577:LPB144 RS11260
gene id: 1913577:LPB144_RS11260
uniprot id: A0A1L3J736
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1913577:LPB144 RS03435
gene id: 1913577:LPB144_RS03435
uniprot id: A0A1L3J2Y9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS10385
gene id: 1913577:LPB144_RS10385
uniprot id: A0A1L3J6J3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1913577:LPB144 RS12710
gene id: 1913577:LPB144_RS12710
uniprot id: A0A1L3J7S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1913577:LPB144 RS03395
gene id: 1913577:LPB144_RS03395
uniprot id: A0A1L3J2X5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1913577:LPB144 RS04560
gene id: 1913577:LPB144_RS04560
uniprot id: A0A1L3J3K3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1913577:LPB144 RS06150
gene id: 1913577:LPB144_RS06150
uniprot id: A0A1L3J4E3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1913577:LPB144 RS09700
gene id: 1913577:LPB144_RS09700
uniprot id: A0A1L3J8J9
names: Similarity
messages: Belongs to the aspartokinase family.

1913577:LPB144 RS01160
gene id: 1913577:LPB144_RS01160
uniprot id: A0A1L3J1T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1913577:LPB144 RS00455
gene id: 1913577:LPB144_RS00455
uniprot id: A0A1L3J1G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS07520
gene id: 1913577:LPB144_RS07520
uniprot id: A0A1L3J516
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1913577:LPB144 RS07615
gene id: 1913577:LPB144_RS07615
uniprot id: A0A1L3J8I7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1913577:LPB144 RS01660
gene id: 1913577:LPB144_RS01660
uniprot id: A0A1L3J241
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1913577:LPB144 RS02630
gene id: 1913577:LPB144_RS02630
uniprot id: A0A1L3J2M4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1913577:LPB144 RS05230
gene id: 1913577:LPB144_RS05230
uniprot id: A0A1L3J3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1913577:LPB144 RS10515
gene id: 1913577:LPB144_RS10515
uniprot id: A0A1L3J6L8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS05795
gene id: 1913577:LPB144_RS05795
uniprot id: A0A1L3J476
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS08770
gene id: 1913577:LPB144_RS08770
uniprot id: A0A1L3J5Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1913577:LPB144 RS01795
gene id: 1913577:LPB144_RS01795
uniprot id: A0A1L3J268
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS06905
gene id: 1913577:LPB144_RS06905
uniprot id: A0A1L3J4U8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1913577:LPB144 RS12600
gene id: 1913577:LPB144_RS12600
uniprot id: A0A1L3J7N5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1913577:LPB144 RS12980
gene id: 1913577:LPB144_RS12980
uniprot id: A0A1L3J8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1913577:LPB144 RS06615
gene id: 1913577:LPB144_RS06615
uniprot id: A0A1L3J4J5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1913577:LPB144 RS10290
gene id: 1913577:LPB144_RS10290
uniprot id: A0A1L3J6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1913577:LPB144 RS11000
gene id: 1913577:LPB144_RS11000
uniprot id: A0A1L3J6Y4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1913577:LPB144 RS09930
gene id: 1913577:LPB144_RS09930
uniprot id: A0A1L3J6D7
names: Similarity
messages: Belongs to the SusD family.

1913577:LPB144 RS13505
gene id: 1913577:LPB144_RS13505
uniprot id: A0A1L3J860
names: Subunit
messages: Monomer.

1913577:LPB144 RS00445
gene id: 1913577:LPB144_RS00445
uniprot id: A0A1L3J1G8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1913577:LPB144 RS10980
gene id: 1913577:LPB144_RS10980
uniprot id: A0A1L3J6Y0
names: Subunit
messages: Homodimer.

1913577:LPB144 RS10405
gene id: 1913577:LPB144_RS10405
uniprot id: A0A1L3J6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1913577:LPB144 RS03195
gene id: 1913577:LPB144_RS03195
uniprot id: A0A1L3J2U0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1913577:LPB144 RS10090
gene id: 1913577:LPB144_RS10090
uniprot id: A0A1L3J6E1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1913577:LPB144 RS13315
gene id: 1913577:LPB144_RS13315
uniprot id: A0A1L3J814
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1913577:LPB144 RS13135
gene id: 1913577:LPB144_RS13135
uniprot id: A0A1L3J7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1913577:LPB144 RS09720
gene id: 1913577:LPB144_RS09720
uniprot id: A0A1L3J669
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1913577:LPB144 RS09480
gene id: 1913577:LPB144_RS09480
uniprot id: A0A1L3J608
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1913577:LPB144 RS03125
gene id: 1913577:LPB144_RS03125
uniprot id: A0A1L3J2S1
names: Similarity
messages: Belongs to the DNA photolyase family.

1913577:LPB144 RS04240
gene id: 1913577:LPB144_RS04240
uniprot id: A0A1L3J8B3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1913577:LPB144 RS05325
gene id: 1913577:LPB144_RS05325
uniprot id: A0A1L3J3Z8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS00430
gene id: 1913577:LPB144_RS00430
uniprot id: A0A1L3J1G5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1913577:LPB144 RS02145
gene id: 1913577:LPB144_RS02145
uniprot id: A0A1L3J2E1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1913577:LPB144 RS01870
gene id: 1913577:LPB144_RS01870
uniprot id: A0A1L3J282
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1913577:LPB144 RS10520
gene id: 1913577:LPB144_RS10520
uniprot id: A0A1L3J6M2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1913577:LPB144 RS01760
gene id: 1913577:LPB144_RS01760
uniprot id: A0A1L3J260
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1913577:LPB144 RS13400
gene id: 1913577:LPB144_RS13400
uniprot id: A0A1L3J846
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1913577:LPB144 RS03120
gene id: 1913577:LPB144_RS03120
uniprot id: A0A1L3J2S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1913577:LPB144 RS04910
gene id: 1913577:LPB144_RS04910
uniprot id: A0A1L3J3Q7
names: Similarity
messages: Belongs to the SusD family.

1913577:LPB144 RS04130
gene id: 1913577:LPB144_RS04130
uniprot id: A0A1L3J3C7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1913577:LPB144 RS05120
gene id: 1913577:LPB144_RS05120
uniprot id: A0A1L3J3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1913577:LPB144 RS12865
gene id: 1913577:LPB144_RS12865
uniprot id: A0A1L3J7U8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS04745
gene id: 1913577:LPB144_RS04745
uniprot id: A0A1L3J3N1
names: Similarity
messages: Belongs to the pirin family.

1913577:LPB144 RS09195
gene id: 1913577:LPB144_RS09195
uniprot id: A0A1L3J8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1913577:LPB144 RS13075
gene id: 1913577:LPB144_RS13075
uniprot id: A0A1L3J7Y4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1913577:LPB144 RS13540
gene id: 1913577:LPB144_RS13540
uniprot id: A0A1L3J882
names: Similarity
messages: Belongs to the DinB family.

1913577:LPB144 RS08300
gene id: 1913577:LPB144_RS08300
uniprot id: A0A1L3J5F7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS01770
gene id: 1913577:LPB144_RS01770
uniprot id: A0A1L3J274
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1913577:LPB144 RS08885
gene id: 1913577:LPB144_RS08885
uniprot id: A0A1L3J5S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1913577:LPB144 RS08220
gene id: 1913577:LPB144_RS08220
uniprot id: A0A1L3J5H1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1913577:LPB144 RS12255
gene id: 1913577:LPB144_RS12255
uniprot id: A0A1L3J7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS08965
gene id: 1913577:LPB144_RS08965
uniprot id: A0A1L3J5S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1913577:LPB144 RS02755
gene id: 1913577:LPB144_RS02755
uniprot id: A0A1L3J2P6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1913577:LPB144 RS00655
gene id: 1913577:LPB144_RS00655
uniprot id: A0A1L3J1I9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1913577:LPB144 RS12300
gene id: 1913577:LPB144_RS12300
uniprot id: A0A1L3J7I9
names: Similarity
messages: Belongs to the SusD family.

1913577:LPB144 RS03830
gene id: 1913577:LPB144_RS03830
uniprot id: A0A1L3J351
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1913577:LPB144 RS10905
gene id: 1913577:LPB144_RS10905
uniprot id: A0A1L3J8M4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS04995
gene id: 1913577:LPB144_RS04995
uniprot id: A0A1L3J3T4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1913577:LPB144 RS04780
gene id: 1913577:LPB144_RS04780
uniprot id: A0A1L3J3N9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1913577:LPB144 RS12345
gene id: 1913577:LPB144_RS12345
uniprot id: A0A1L3J7L7
names: Similarity
messages: Belongs to the glutamate synthase family.

1913577:LPB144 RS09100
gene id: 1913577:LPB144_RS09100
uniprot id: A0A1L3J5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1913577:LPB144 RS11940
gene id: 1913577:LPB144_RS11940
uniprot id: A0A1L3J7B3
names: Similarity
messages: Belongs to the universal stress protein A family.

1913577:LPB144 RS02465
gene id: 1913577:LPB144_RS02465
uniprot id: A0A1L3J2K0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1913577:LPB144 RS04790
gene id: 1913577:LPB144_RS04790
uniprot id: A0A1L3J3M7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS09035
gene id: 1913577:LPB144_RS09035
uniprot id: A0A1L3J8J1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1913577:LPB144 RS08750
gene id: 1913577:LPB144_RS08750
uniprot id: A0A1L3J8K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1913577:LPB144 RS03405
gene id: 1913577:LPB144_RS03405
uniprot id: A0A1L3J2Y1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10730
gene id: 1913577:LPB144_RS10730
uniprot id: A0A1L3J6P2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1913577:LPB144 RS13145
gene id: 1913577:LPB144_RS13145
uniprot id: A0A1L3J819
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS07010
gene id: 1913577:LPB144_RS07010
uniprot id: A0A1L3J4V4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS11490
gene id: 1913577:LPB144_RS11490
uniprot id: A0A1L3J738
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1913577:LPB144 RS02790
gene id: 1913577:LPB144_RS02790
uniprot id: A0A1L3J2Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1913577:LPB144 RS09350
gene id: 1913577:LPB144_RS09350
uniprot id: A0A1L3J600
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1913577:LPB144 RS07935
gene id: 1913577:LPB144_RS07935
uniprot id: A0A1L3J5B5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1913577:LPB144 RS08675
gene id: 1913577:LPB144_RS08675
uniprot id: A0A1L3J5M0
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

1913577:LPB144 RS10985
gene id: 1913577:LPB144_RS10985
uniprot id: A0A1L3J6X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS03900
gene id: 1913577:LPB144_RS03900
uniprot id: A0A1L3J373
names: Subcellular Location Annotation
messages: Cytoplasm

1913577:LPB144 RS00935
gene id: 1913577:LPB144_RS00935
uniprot id: A0A1L3J1R0
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1913577:LPB144 RS13010
gene id: 1913577:LPB144_RS13010
uniprot id: A0A1L3J7Z8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS09950
gene id: 1913577:LPB144_RS09950
uniprot id: A0A1L3J695
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1913577:LPB144 RS02305
gene id: 1913577:LPB144_RS02305
uniprot id: A0A1L3J2F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10965
gene id: 1913577:LPB144_RS10965
uniprot id: A0A1L3J6U7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1913577:LPB144 RS11235
gene id: 1913577:LPB144_RS11235
uniprot id: A0A1L3J706
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1913577:LPB144 RS06715
gene id: 1913577:LPB144_RS06715
uniprot id: A0A1L3J4M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS04105
gene id: 1913577:LPB144_RS04105
uniprot id: A0A1L3J3B2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913577:LPB144 RS03375
gene id: 1913577:LPB144_RS03375
uniprot id: A0A1L3J2X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1913577:LPB144 RS02060
gene id: 1913577:LPB144_RS02060
uniprot id: A0A1L3J2C2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1913577:LPB144 RS02215
gene id: 1913577:LPB144_RS02215
uniprot id: A0A1L3J2E5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1913577:LPB144 RS11620
gene id: 1913577:LPB144_RS11620
uniprot id: A0A1L3J8L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1913577:LPB144 RS00260
gene id: 1913577:LPB144_RS00260
uniprot id: A0A1L3J1D4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1913577:LPB144 RS09730
gene id: 1913577:LPB144_RS09730
uniprot id: A0A1L3J672
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1913577:LPB144 RS13000
gene id: 1913577:LPB144_RS13000
uniprot id: A0A1L3J7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS09755
gene id: 1913577:LPB144_RS09755
uniprot id: A0A1L3J687
names: Similarity
messages: Belongs to the ribF family.

1913577:LPB144 RS08190
gene id: 1913577:LPB144_RS08190
uniprot id: A0A1L3J5E5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS03190
gene id: 1913577:LPB144_RS03190
uniprot id: A0A1L3J2T9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS11680
gene id: 1913577:LPB144_RS11680
uniprot id: A0A1L3J791
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS07100
gene id: 1913577:LPB144_RS07100
uniprot id: A0A1L3J4U5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1913577:LPB144 RS07420
gene id: 1913577:LPB144_RS07420
uniprot id: A0A1L3J4X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1913577:LPB144 RS11615
gene id: 1913577:LPB144_RS11615
uniprot id: A0A1L3J781
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1913577:LPB144 RS11205
gene id: 1913577:LPB144_RS11205
uniprot id: A0A1L3J6X4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1913577:LPB144 RS07485
gene id: 1913577:LPB144_RS07485
uniprot id: A0A1L3J539
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1913577:LPB144 RS07950
gene id: 1913577:LPB144_RS07950
uniprot id: A0A1L3J5A7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1913577:LPB144 RS04840
gene id: 1913577:LPB144_RS04840
uniprot id: A0A1L3J3N6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913577:LPB144 RS03885
gene id: 1913577:LPB144_RS03885
uniprot id: A0A1L3J384
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1913577:LPB144 RS04515
gene id: 1913577:LPB144_RS04515
uniprot id: A0A1L3J3J6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1913577:LPB144 RS01480
gene id: 1913577:LPB144_RS01480
uniprot id: A0A1L3J1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1913577:LPB144 RS06040
gene id: 1913577:LPB144_RS06040
uniprot id: A0A1L3J4A5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1913577:LPB144 RS00965
gene id: 1913577:LPB144_RS00965
uniprot id: A0A1L3J1R9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1913577:LPB144 RS11630
gene id: 1913577:LPB144_RS11630
uniprot id: A0A1L3J788
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1913577:LPB144 RS07225
gene id: 1913577:LPB144_RS07225
uniprot id: A0A1L3J4W3
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS13230
gene id: 1913577:LPB144_RS13230
uniprot id: A0A1L3J803
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1913577:LPB144 RS07980
gene id: 1913577:LPB144_RS07980
uniprot id: A0A1L3J5B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1913577:LPB144 RS07280
gene id: 1913577:LPB144_RS07280
uniprot id: A0A1L3J4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1913577:LPB144 RS00925
gene id: 1913577:LPB144_RS00925
uniprot id: A0A1L3J1Q4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1913577:LPB144 RS09725
gene id: 1913577:LPB144_RS09725
uniprot id: A0A1L3J686
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1913577:LPB144 RS10000
gene id: 1913577:LPB144_RS10000
uniprot id: A0A1L3J6D6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1913577:LPB144 RS01145
gene id: 1913577:LPB144_RS01145
uniprot id: A0A1L3J1U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1913577:LPB144 RS12670
gene id: 1913577:LPB144_RS12670
uniprot id: A0A1L3J7S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1913577:LPB144 RS10510
gene id: 1913577:LPB144_RS10510
uniprot id: A0A1L3J6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1913577:LPB144 RS08550
gene id: 1913577:LPB144_RS08550
uniprot id: A0A1L3J5M3
names: Similarity
messages: Belongs to the universal stress protein A family.

1913577:LPB144 RS01775
gene id: 1913577:LPB144_RS01775
uniprot id: A0A1L3J257
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1913577:LPB144 RS04195
gene id: 1913577:LPB144_RS04195
uniprot id: A0A1L3J3D8
names: Similarity
messages: Belongs to the peptidase C40 family.

1913577:LPB144 RS00200
gene id: 1913577:LPB144_RS00200
uniprot id: A0A1L3J1C4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1913577:LPB144 RS12760
gene id: 1913577:LPB144_RS12760
uniprot id: A0A1L3J7S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1913577:LPB144 RS00170
gene id: 1913577:LPB144_RS00170
uniprot id: A0A1L3J1C9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1913577:LPB144 RS12525
gene id: 1913577:LPB144_RS12525
uniprot id: A0A1L3J7P8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS03460
gene id: 1913577:LPB144_RS03460
uniprot id: A0A1L3J2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1913577:LPB144 RS04860
gene id: 1913577:LPB144_RS04860
uniprot id: A0A1L3J3N7
names: Subcellular Location Annotation
messages: Secreted

1913577:LPB144 RS07235
gene id: 1913577:LPB144_RS07235
uniprot id: A0A1L3J4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS06540
gene id: 1913577:LPB144_RS06540
uniprot id: A0A1L3J4I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1913577:LPB144 RS04565
gene id: 1913577:LPB144_RS04565
uniprot id: A0A1L3J3I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1913577:LPB144 RS04965
gene id: 1913577:LPB144_RS04965
uniprot id: A0A1L3J3Q6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS12680
gene id: 1913577:LPB144_RS12680
uniprot id: A0A1L3J7S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1913577:LPB144 RS10325
gene id: 1913577:LPB144_RS10325
uniprot id: A0A1L3J6I6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1913577:LPB144 RS03300
gene id: 1913577:LPB144_RS03300
uniprot id: A0A1L3J2W4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS12170
gene id: 1913577:LPB144_RS12170
uniprot id: A0A1L3J7G1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS02310
gene id: 1913577:LPB144_RS02310
uniprot id: A0A1L3J2H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1913577:LPB144 RS09170
gene id: 1913577:LPB144_RS09170
uniprot id: A0A1L3J601
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS00480
gene id: 1913577:LPB144_RS00480
uniprot id: A0A1L3J1H9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1913577:LPB144 RS10580
gene id: 1913577:LPB144_RS10580
uniprot id: A0A1L3J6R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1913577:LPB144 RS06610
gene id: 1913577:LPB144_RS06610
uniprot id: A0A1L3J4K6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1913577:LPB144 RS01780
gene id: 1913577:LPB144_RS01780
uniprot id: A0A1L3J270
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1913577:LPB144 RS01190
gene id: 1913577:LPB144_RS01190
uniprot id: A0A1L3J1W0
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS06555
gene id: 1913577:LPB144_RS06555
uniprot id: A0A1L3J4M1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1913577:LPB144 RS03390
gene id: 1913577:LPB144_RS03390
uniprot id: A0A1L3J2X7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1913577:LPB144 RS09570
gene id: 1913577:LPB144_RS09570
uniprot id: A0A1L3J635
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS02705
gene id: 1913577:LPB144_RS02705
uniprot id: A0A1L3J2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1913577:LPB144 RS12375
gene id: 1913577:LPB144_RS12375
uniprot id: A0A1L3J7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1913577:LPB144 RS10585
gene id: 1913577:LPB144_RS10585
uniprot id: A0A1L3J6Q6
names: Similarity
messages: Belongs to the peptidase S41A family.

1913577:LPB144 RS13425
gene id: 1913577:LPB144_RS13425
uniprot id: A0A1L3J838
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

1913577:LPB144 RS06695
gene id: 1913577:LPB144_RS06695
uniprot id: A0A1L3J4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1913577:LPB144 RS12040
gene id: 1913577:LPB144_RS12040
uniprot id: A0A1L3J7H0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS03560
gene id: 1913577:LPB144_RS03560
uniprot id: A0A1L3J305
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1913577:LPB144 RS01765
gene id: 1913577:LPB144_RS01765
uniprot id: A0A1L3J263
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1913577:LPB144 RS11645
gene id: 1913577:LPB144_RS11645
uniprot id: A0A1L3J759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1913577:LPB144 RS04330
gene id: 1913577:LPB144_RS04330
uniprot id: A0A1L3J3F2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1913577:LPB144 RS12665
gene id: 1913577:LPB144_RS12665
uniprot id: A0A1L3J7S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1913577:LPB144 RS12015
gene id: 1913577:LPB144_RS12015
uniprot id: A0A1L3J7D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS09530
gene id: 1913577:LPB144_RS09530
uniprot id: A0A1L3J620
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS00485
gene id: 1913577:LPB144_RS00485
uniprot id: A0A1L3J1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1913577:LPB144 RS08760
gene id: 1913577:LPB144_RS08760
uniprot id: A0A1L3J5M2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1913577:LPB144 RS01000
gene id: 1913577:LPB144_RS01000
uniprot id: A0A1L3J1R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1913577:LPB144 RS12365
gene id: 1913577:LPB144_RS12365
uniprot id: A0A1L3J7J8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1913577:LPB144 RS02265
gene id: 1913577:LPB144_RS02265
uniprot id: A0A1L3J2F5
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1913577:LPB144 RS07220
gene id: 1913577:LPB144_RS07220
uniprot id: A0A1L3J4X5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1913577:LPB144 RS12005
gene id: 1913577:LPB144_RS12005
uniprot id: A0A1L3J7D4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1913577:LPB144 RS08275
gene id: 1913577:LPB144_RS08275
uniprot id: A0A1L3J5H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1913577:LPB144 RS04765
gene id: 1913577:LPB144_RS04765
uniprot id: A0A1L3J3P0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1913577:LPB144 RS02515
gene id: 1913577:LPB144_RS02515
uniprot id: A0A1L3J2K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1913577:LPB144 RS06980
gene id: 1913577:LPB144_RS06980
uniprot id: A0A1L3J4U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1913577:LPB144 RS08340
gene id: 1913577:LPB144_RS08340
uniprot id: A0A1L3J5G7
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1913577:LPB144 RS11895
gene id: 1913577:LPB144_RS11895
uniprot id: A0A1L3J7B8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1913577:LPB144 RS12150
gene id: 1913577:LPB144_RS12150
uniprot id: A0A1L3J7F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS02545
gene id: 1913577:LPB144_RS02545
uniprot id: A0A1L3J2K3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1913577:LPB144 RS10820
gene id: 1913577:LPB144_RS10820
uniprot id: A0A1L3J6T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1913577:LPB144 RS12520
gene id: 1913577:LPB144_RS12520
uniprot id: A0A1L3J7K9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1913577:LPB144 RS07570
gene id: 1913577:LPB144_RS07570
uniprot id: A0A1L3J525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1913577:LPB144 RS04935
gene id: 1913577:LPB144_RS04935
uniprot id: A0A1L3J3T7
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS05760
gene id: 1913577:LPB144_RS05760
uniprot id: A0A1L3J457
names: Similarity
messages: Belongs to the pirin family.

1913577:LPB144 RS01725
gene id: 1913577:LPB144_RS01725
uniprot id: A0A1L3J247
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS12705
gene id: 1913577:LPB144_RS12705
uniprot id: A0A1L3J7R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1913577:LPB144 RS09905
gene id: 1913577:LPB144_RS09905
uniprot id: A0A1L3J690
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1913577:LPB144 RS03420
gene id: 1913577:LPB144_RS03420
uniprot id: A0A1L3J2Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1913577:LPB144 RS12290
gene id: 1913577:LPB144_RS12290
uniprot id: A0A1L3J7H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1913577:LPB144 RS01980
gene id: 1913577:LPB144_RS01980
uniprot id: A0A1L3J2A8
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS12270
gene id: 1913577:LPB144_RS12270
uniprot id: A0A1L3J7L4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS03150
gene id: 1913577:LPB144_RS03150
uniprot id: A0A1L3J2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1913577:LPB144 RS11400
gene id: 1913577:LPB144_RS11400
uniprot id: A0A1L3J744
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1913577:LPB144 RS06335
gene id: 1913577:LPB144_RS06335
uniprot id: A0A1L3J4F0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1913577:LPB144 RS10530
gene id: 1913577:LPB144_RS10530
uniprot id: A0A1L3J6P9
names: Similarity
messages: Belongs to the peptidase C40 family.

1913577:LPB144 RS01560
gene id: 1913577:LPB144_RS01560
uniprot id: A0A1L3J234
names: Similarity
messages: Belongs to the aldose epimerase family.

1913577:LPB144 RS03230
gene id: 1913577:LPB144_RS03230
uniprot id: A0A1L3J2U7
names: Similarity
messages: Belongs to the threonine aldolase family.

1913577:LPB144 RS01220
gene id: 1913577:LPB144_RS01220
uniprot id: A0A1L3J1W2
names: Similarity
messages: Belongs to the ParB family.

1913577:LPB144 RS07705
gene id: 1913577:LPB144_RS07705
uniprot id: A0A1L3J575
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913577:LPB144 RS03490
gene id: 1913577:LPB144_RS03490
uniprot id: A0A1L3J2Z5
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS12815
gene id: 1913577:LPB144_RS12815
uniprot id: A0A1L3J7T8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1913577:LPB144 RS04550
gene id: 1913577:LPB144_RS04550
uniprot id: A0A1L3J3H6
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS06005
gene id: 1913577:LPB144_RS06005
uniprot id: A0A1L3J4C2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1913577:LPB144 RS09625
gene id: 1913577:LPB144_RS09625
uniprot id: A0A1L3J652
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1913577:LPB144 RS04100
gene id: 1913577:LPB144_RS04100
uniprot id: A0A1L3J3A1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913577:LPB144 RS01520
gene id: 1913577:LPB144_RS01520
uniprot id: A0A1L3J219
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1913577:LPB144 RS09475
gene id: 1913577:LPB144_RS09475
uniprot id: A0A1L3J606
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1913577:LPB144 RS11020
gene id: 1913577:LPB144_RS11020
uniprot id: A0A1L3J6W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1913577:LPB144 RS12430
gene id: 1913577:LPB144_RS12430
uniprot id: A0A1L3J7P1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1913577:LPB144 RS05825
gene id: 1913577:LPB144_RS05825
uniprot id: A0A1L3J466
names: Similarity
messages: Belongs to the peptidase S9C family.

1913577:LPB144 RS11110
gene id: 1913577:LPB144_RS11110
uniprot id: A0A1L3J6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1913577:LPB144 RS03730
gene id: 1913577:LPB144_RS03730
uniprot id: A0A1L3J342
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1913577:LPB144 RS12100
gene id: 1913577:LPB144_RS12100
uniprot id: A0A1L3J7I4
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS10605
gene id: 1913577:LPB144_RS10605
uniprot id: A0A1L3J6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1913577:LPB144 RS00115
gene id: 1913577:LPB144_RS00115
uniprot id: A0A1L3J1A6
names: Subcellular Location Annotation
messages: Nucleus

1913577:LPB144 RS05070
gene id: 1913577:LPB144_RS05070
uniprot id: A0A1L3J3S5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1913577:LPB144 RS01135
gene id: 1913577:LPB144_RS01135
uniprot id: A0A1L3J1U7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1913577:LPB144 RS01640
gene id: 1913577:LPB144_RS01640
uniprot id: A0A1L3J243
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1913577:LPB144 RS00085
gene id: 1913577:LPB144_RS00085
uniprot id: A0A1L3J1A2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1913577:LPB144 RS04190
gene id: 1913577:LPB144_RS04190
uniprot id: A0A1L3J3D7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1913577:LPB144 RS09040
gene id: 1913577:LPB144_RS09040
uniprot id: A0A1L3J5S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1913577:LPB144 RS00535
gene id: 1913577:LPB144_RS00535
uniprot id: A0A1L3J1I7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS03055
gene id: 1913577:LPB144_RS03055
uniprot id: A0A1L3J2Q7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS00285
gene id: 1913577:LPB144_RS00285
uniprot id: A0A1L3J1E8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913577:LPB144 RS09335
gene id: 1913577:LPB144_RS09335
uniprot id: A0A1L3J607
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS02065
gene id: 1913577:LPB144_RS02065
uniprot id: A0A1L3J2B4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1913577:LPB144 RS09935
gene id: 1913577:LPB144_RS09935
uniprot id: A0A1L3J6A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS05960
gene id: 1913577:LPB144_RS05960
uniprot id: A0A1L3J489
names: Similarity
messages: Belongs to the group II decarboxylase family.

1913577:LPB144 RS12905
gene id: 1913577:LPB144_RS12905
uniprot id: A0A1L3J7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1913577:LPB144 RS00955
gene id: 1913577:LPB144_RS00955
uniprot id: A0A1L3J1R2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1913577:LPB144 RS04415
gene id: 1913577:LPB144_RS04415
uniprot id: A0A1L3J3H4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1913577:LPB144 RS11585
gene id: 1913577:LPB144_RS11585
uniprot id: A0A1L3J796
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1913577:LPB144 RS00540
gene id: 1913577:LPB144_RS00540
uniprot id: A0A1L3J1I4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1913577:LPB144 RS09305
gene id: 1913577:LPB144_RS09305
uniprot id: A0A1L3J5X4
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1913577:LPB144 RS10970
gene id: 1913577:LPB144_RS10970
uniprot id: A0A1L3J6V9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS09520
gene id: 1913577:LPB144_RS09520
uniprot id: A0A1L3J626
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS02035
gene id: 1913577:LPB144_RS02035
uniprot id: A0A1L3J2A6
names: Similarity
messages: Belongs to the Dps family.

1913577:LPB144 RS12120
gene id: 1913577:LPB144_RS12120
uniprot id: A0A1L3J7F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1913577:LPB144 RS04155
gene id: 1913577:LPB144_RS04155
uniprot id: A0A1L3J3B1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1913577:LPB144 RS04615
gene id: 1913577:LPB144_RS04615
uniprot id: A0A1L3J3J0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1913577:LPB144 RS10240
gene id: 1913577:LPB144_RS10240
uniprot id: A0A1L3J6J7
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1913577:LPB144 RS03340
gene id: 1913577:LPB144_RS03340
uniprot id: A0A1L3J2W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1913577:LPB144 RS08310
gene id: 1913577:LPB144_RS08310
uniprot id: A0A1L3J5E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS06720
gene id: 1913577:LPB144_RS06720
uniprot id: A0A1L3J4L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1913577:LPB144 RS01010
gene id: 1913577:LPB144_RS01010
uniprot id: A0A1L3J1S3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1913577:LPB144 RS11105
gene id: 1913577:LPB144_RS11105
uniprot id: A0A1L3J711
names: Similarity
messages: Belongs to the SCO1/2 family.

1913577:LPB144 RS10295
gene id: 1913577:LPB144_RS10295
uniprot id: A0A1L3J6H5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1913577:LPB144 RS02290
gene id: 1913577:LPB144_RS02290
uniprot id: A0A1L3J2F8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS05925
gene id: 1913577:LPB144_RS05925
uniprot id: A0A1L3J478
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS00605
gene id: 1913577:LPB144_RS00605
uniprot id: A0A1L3J1J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1913577:LPB144 RS07430
gene id: 1913577:LPB144_RS07430
uniprot id: A0A1L3J517
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1913577:LPB144 RS08135
gene id: 1913577:LPB144_RS08135
uniprot id: A0A1L3J8J7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1913577:LPB144 RS07180
gene id: 1913577:LPB144_RS07180
uniprot id: A0A1L3J4Y8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10815
gene id: 1913577:LPB144_RS10815
uniprot id: A0A1L3J6S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1913577:LPB144 RS08955
gene id: 1913577:LPB144_RS08955
uniprot id: A0A1L3J5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1913577:LPB144 RS09995
gene id: 1913577:LPB144_RS09995
uniprot id: A0A1L3J6C0
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1913577:LPB144 RS07645
gene id: 1913577:LPB144_RS07645
uniprot id: A0A1L3J558
names: Similarity
messages: Belongs to the SusD family.

1913577:LPB144 RS03655
gene id: 1913577:LPB144_RS03655
uniprot id: A0A1L3J327
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS08765
gene id: 1913577:LPB144_RS08765
uniprot id: A0A1L3J5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1913577:LPB144 RS02670
gene id: 1913577:LPB144_RS02670
uniprot id: A0A1L3J2M1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1913577:LPB144 RS11095
gene id: 1913577:LPB144_RS11095
uniprot id: A0A1L3J6W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1913577:LPB144 RS12820
gene id: 1913577:LPB144_RS12820
uniprot id: A0A1L3J7U5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1913577:LPB144 RS07905
gene id: 1913577:LPB144_RS07905
uniprot id: A0A1L3J587
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1913577:LPB144 RS10835
gene id: 1913577:LPB144_RS10835
uniprot id: A0A1L3J6R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1913577:LPB144 RS10625
gene id: 1913577:LPB144_RS10625
uniprot id: A0A1L3J6P4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913577:LPB144 RS08685
gene id: 1913577:LPB144_RS08685
uniprot id: A0A1L3J5M6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1913577:LPB144 RS03645
gene id: 1913577:LPB144_RS03645
uniprot id: A0A1L3J312
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1913577:LPB144 RS11770
gene id: 1913577:LPB144_RS11770
uniprot id: A0A1L3J7C6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1913577:LPB144 RS10310
gene id: 1913577:LPB144_RS10310
uniprot id: A0A1L3J6L5
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1913577:LPB144 RS04400
gene id: 1913577:LPB144_RS04400
uniprot id: A0A1L3J3H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS11760
gene id: 1913577:LPB144_RS11760
uniprot id: A0A1L3J7D1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS01740
gene id: 1913577:LPB144_RS01740
uniprot id: A0A1L3J236
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS07285
gene id: 1913577:LPB144_RS07285
uniprot id: A0A1L3J4X8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS07970
gene id: 1913577:LPB144_RS07970
uniprot id: A0A1L3J581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1913577:LPB144 RS12695
gene id: 1913577:LPB144_RS12695
uniprot id: A0A1L3J7Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1913577:LPB144 RS06010
gene id: 1913577:LPB144_RS06010
uniprot id: A0A1L3J499
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1913577:LPB144 RS08105
gene id: 1913577:LPB144_RS08105
uniprot id: A0A1L3J8F4
names: Similarity
messages: Belongs to the group II decarboxylase family.

1913577:LPB144 RS07310
gene id: 1913577:LPB144_RS07310
uniprot id: A0A1L3J503
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS08445
gene id: 1913577:LPB144_RS08445
uniprot id: A0A1L3J5K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1913577:LPB144 RS11160
gene id: 1913577:LPB144_RS11160
uniprot id: A0A1L3J721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS01510
gene id: 1913577:LPB144_RS01510
uniprot id: A0A1L3J224
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1913577:LPB144 RS13060
gene id: 1913577:LPB144_RS13060
uniprot id: A0A1L3J807
names: Similarity
messages: Belongs to the peptidase S13 family.

1913577:LPB144 RS03555
gene id: 1913577:LPB144_RS03555
uniprot id: A0A1L3J308
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1913577:LPB144 RS00420
gene id: 1913577:LPB144_RS00420
uniprot id: A0A1L3J1F4
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1913577:LPB144 RS10460
gene id: 1913577:LPB144_RS10460
uniprot id: A0A1L3J6L6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1913577:LPB144 RS12155
gene id: 1913577:LPB144_RS12155
uniprot id: A0A1L3J7J4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1913577:LPB144 RS13190
gene id: 1913577:LPB144_RS13190
uniprot id: A0A1L3J806
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1913577:LPB144 RS01095
gene id: 1913577:LPB144_RS01095
uniprot id: A0A1L3J1T4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1913577:LPB144 RS01600
gene id: 1913577:LPB144_RS01600
uniprot id: A0A1L3J233
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1913577:LPB144 RS04225
gene id: 1913577:LPB144_RS04225
uniprot id: A0A1L3J3C9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS04580
gene id: 1913577:LPB144_RS04580
uniprot id: A0A1L3J3K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1913577:LPB144 RS07395
gene id: 1913577:LPB144_RS07395
uniprot id: A0A1L3J8H0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1913577:LPB144 RS00825
gene id: 1913577:LPB144_RS00825
uniprot id: A0A1L3J1N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1913577:LPB144 RS00850
gene id: 1913577:LPB144_RS00850
uniprot id: A0A1L3J1N7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1913577:LPB144 RS01090
gene id: 1913577:LPB144_RS01090
uniprot id: A0A1L3J1U2
names: Similarity
messages: Belongs to the Fur family.

1913577:LPB144 RS05900
gene id: 1913577:LPB144_RS05900
uniprot id: A0A1L3J4A2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS11600
gene id: 1913577:LPB144_RS11600
uniprot id: A0A1L3J763
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1913577:LPB144 RS03415
gene id: 1913577:LPB144_RS03415
uniprot id: A0A1L3J2X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1913577:LPB144 RS02000
gene id: 1913577:LPB144_RS02000
uniprot id: A0A1L3J286
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS11510
gene id: 1913577:LPB144_RS11510
uniprot id: A0A1L3J761
names: Similarity
messages: Belongs to the peptidase M13 family.

1913577:LPB144 RS00130
gene id: 1913577:LPB144_RS00130
uniprot id: A0A1L3J1B3
names: Similarity
messages: Belongs to the NusB family.

1913577:LPB144 RS03780
gene id: 1913577:LPB144_RS03780
uniprot id: A0A1L3J8C1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1913577:LPB144 RS01990
gene id: 1913577:LPB144_RS01990
uniprot id: A0A1L3J2B3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1913577:LPB144 RS01635
gene id: 1913577:LPB144_RS01635
uniprot id: A0A1L3J216
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1913577:LPB144 RS04605
gene id: 1913577:LPB144_RS04605
uniprot id: A0A1L3J3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1913577:LPB144 RS00665
gene id: 1913577:LPB144_RS00665
uniprot id: A0A1L3J879
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1913577:LPB144 RS09490
gene id: 1913577:LPB144_RS09490
uniprot id: A0A1L3J632
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS01735
gene id: 1913577:LPB144_RS01735
uniprot id: A0A1L3J249
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1913577:LPB144 RS13270
gene id: 1913577:LPB144_RS13270
uniprot id: A0A1L3J849
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1913577:LPB144 RS10725
gene id: 1913577:LPB144_RS10725
uniprot id: A0A1L3J6S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1913577:LPB144 RS00330
gene id: 1913577:LPB144_RS00330
uniprot id: A0A1L3J1E6
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS02070
gene id: 1913577:LPB144_RS02070
uniprot id: A0A1L3J2B5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1913577:LPB144 RS07500
gene id: 1913577:LPB144_RS07500
uniprot id: A0A1L3J521
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1913577:LPB144 RS07975
gene id: 1913577:LPB144_RS07975
uniprot id: A0A1L3J5D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS12895
gene id: 1913577:LPB144_RS12895
uniprot id: A0A1L3J7Y1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS12130
gene id: 1913577:LPB144_RS12130
uniprot id: A0A1L3J7G8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS03625
gene id: 1913577:LPB144_RS03625
uniprot id: A0A1L3J314
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1913577:LPB144 RS01605
gene id: 1913577:LPB144_RS01605
uniprot id: A0A1L3J232
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1913577:LPB144 RS04815
gene id: 1913577:LPB144_RS04815
uniprot id: A0A1L3J3Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1913577:LPB144 RS06660
gene id: 1913577:LPB144_RS06660
uniprot id: A0A1L3J4M0
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS04680
gene id: 1913577:LPB144_RS04680
uniprot id: A0A1L3J3M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1913577:LPB144 RS08655
gene id: 1913577:LPB144_RS08655
uniprot id: A0A1L3J5N6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1913577:LPB144 RS10535
gene id: 1913577:LPB144_RS10535
uniprot id: A0A1L3J8L3
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1913577:LPB144 RS09505
gene id: 1913577:LPB144_RS09505
uniprot id: A0A1L3J653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1913577:LPB144 RS01875
gene id: 1913577:LPB144_RS01875
uniprot id: A0A1L3J281
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1913577:LPB144 RS02565
gene id: 1913577:LPB144_RS02565
uniprot id: A0A1L3J2L5
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1913577:LPB144 RS01100
gene id: 1913577:LPB144_RS01100
uniprot id: A0A1L3J1R3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1913577:LPB144 RS10415
gene id: 1913577:LPB144_RS10415
uniprot id: A0A1L3J6M4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS07110
gene id: 1913577:LPB144_RS07110
uniprot id: A0A1L3J4U7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1913577:LPB144 RS03910
gene id: 1913577:LPB144_RS03910
uniprot id: A0A1L3J355
names: Subcellular Location Annotation
messages: Cytoplasm

1913577:LPB144 RS08265
gene id: 1913577:LPB144_RS08265
uniprot id: A0A1L3J5I0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS05185
gene id: 1913577:LPB144_RS05185
uniprot id: A0A1L3J3V0
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS11550
gene id: 1913577:LPB144_RS11550
uniprot id: A0A1L3J758
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10830
gene id: 1913577:LPB144_RS10830
uniprot id: A0A1L3J6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1913577:LPB144 RS06215
gene id: 1913577:LPB144_RS06215
uniprot id: A0A1L3J4D3
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS03605
gene id: 1913577:LPB144_RS03605
uniprot id: A0A1L3J319
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS07410
gene id: 1913577:LPB144_RS07410
uniprot id: A0A1L3J4Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1913577:LPB144 RS05100
gene id: 1913577:LPB144_RS05100
uniprot id: A0A1L3J3V9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS10690
gene id: 1913577:LPB144_RS10690
uniprot id: A0A1L3J6S3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1913577:LPB144 RS04850
gene id: 1913577:LPB144_RS04850
uniprot id: A0A1L3J8A2
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

1913577:LPB144 RS00350
gene id: 1913577:LPB144_RS00350
uniprot id: A0A1L3J1F9
names: Similarity
messages: Belongs to the UPF0047 family.

1913577:LPB144 RS12065
gene id: 1913577:LPB144_RS12065
uniprot id: A0A1L3J7D9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS10595
gene id: 1913577:LPB144_RS10595
uniprot id: A0A1L3J6N9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1913577:LPB144 RS10845
gene id: 1913577:LPB144_RS10845
uniprot id: A0A1L3J6V6
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS08485
gene id: 1913577:LPB144_RS08485
uniprot id: A0A1L3J5K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1913577:LPB144 RS00335
gene id: 1913577:LPB144_RS00335
uniprot id: A0A1L3J1E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1913577:LPB144 RS02535
gene id: 1913577:LPB144_RS02535
uniprot id: A0A1L3J2L0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1913577:LPB144 RS13095
gene id: 1913577:LPB144_RS13095
uniprot id: A0A1L3J810
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1913577:LPB144 RS13355
gene id: 1913577:LPB144_RS13355
uniprot id: A0A1L3J844
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1913577:LPB144 RS02030
gene id: 1913577:LPB144_RS02030
uniprot id: A0A1L3J2C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1913577:LPB144 RS12700
gene id: 1913577:LPB144_RS12700
uniprot id: A0A1L3J7Q5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1913577:LPB144 RS12655
gene id: 1913577:LPB144_RS12655
uniprot id: A0A1L3J7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS11720
gene id: 1913577:LPB144_RS11720
uniprot id: A0A1L3J784
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1913577:LPB144 RS09440
gene id: 1913577:LPB144_RS09440
uniprot id: A0A1L3J627
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1913577:LPB144 RS06185
gene id: 1913577:LPB144_RS06185
uniprot id: A0A1L3J4B7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1913577:LPB144 RS07275
gene id: 1913577:LPB144_RS07275
uniprot id: A0A1L3J4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1913577:LPB144 RS11040
gene id: 1913577:LPB144_RS11040
uniprot id: A0A1L3J6V0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1913577:LPB144 RS05785
gene id: 1913577:LPB144_RS05785
uniprot id: A0A1L3J475
names: Similarity
messages: Belongs to the AHA1 family.

1913577:LPB144 RS10210
gene id: 1913577:LPB144_RS10210
uniprot id: A0A1L3J6I8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1913577:LPB144 RS04610
gene id: 1913577:LPB144_RS04610
uniprot id: A0A1L3J3L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1913577:LPB144 RS09565
gene id: 1913577:LPB144_RS09565
uniprot id: A0A1L3J654
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1913577:LPB144 RS11015
gene id: 1913577:LPB144_RS11015
uniprot id: A0A1L3J6V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1913577:LPB144 RS06410
gene id: 1913577:LPB144_RS06410
uniprot id: A0A1L3J4K5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1913577:LPB144 RS10825
gene id: 1913577:LPB144_RS10825
uniprot id: A0A1L3J6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1913577:LPB144 RS03455
gene id: 1913577:LPB144_RS03455
uniprot id: A0A1L3J2Y8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS04310
gene id: 1913577:LPB144_RS04310
uniprot id: A0A1L3J3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1913577:LPB144 RS06545
gene id: 1913577:LPB144_RS06545
uniprot id: A0A1L3J4M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1913577:LPB144 RS01805
gene id: 1913577:LPB144_RS01805
uniprot id: A0A1L3J265
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1913577:LPB144 RS09900
gene id: 1913577:LPB144_RS09900
uniprot id: A0A1L3J685
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS00560
gene id: 1913577:LPB144_RS00560
uniprot id: A0A1L3J1I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1913577:LPB144 RS00125
gene id: 1913577:LPB144_RS00125
uniprot id: A0A1L3J1B8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1913577:LPB144 RS01720
gene id: 1913577:LPB144_RS01720
uniprot id: A0A1L3J264
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1913577:LPB144 RS11565
gene id: 1913577:LPB144_RS11565
uniprot id: A0A1L3J773
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1913577:LPB144 RS13265
gene id: 1913577:LPB144_RS13265
uniprot id: A0A1L3J804
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1913577:LPB144 RS11575
gene id: 1913577:LPB144_RS11575
uniprot id: A0A1L3J785
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1913577:LPB144 RS06970
gene id: 1913577:LPB144_RS06970
uniprot id: A0A1L3J4V6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1913577:LPB144 RS01915
gene id: 1913577:LPB144_RS01915
uniprot id: A0A1L3J285
names: Similarity
messages: Belongs to the CvfB family.

1913577:LPB144 RS11395
gene id: 1913577:LPB144_RS11395
uniprot id: A0A1L3J727
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1913577:LPB144 RS09460
gene id: 1913577:LPB144_RS09460
uniprot id: A0A1L3J640
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1913577:LPB144 RS10100
gene id: 1913577:LPB144_RS10100
uniprot id: A0A1L3J6G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1913577:LPB144 RS13160
gene id: 1913577:LPB144_RS13160
uniprot id: A0A1L3J7Y2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1913577:LPB144 RS10810
gene id: 1913577:LPB144_RS10810
uniprot id: A0A1L3J6R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1913577:LPB144 RS06245
gene id: 1913577:LPB144_RS06245
uniprot id: A0A1L3J4E4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1913577:LPB144 RS12830
gene id: 1913577:LPB144_RS12830
uniprot id: A0A1L3J7S1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1913577:LPB144 RS10620
gene id: 1913577:LPB144_RS10620
uniprot id: A0A1L3J6Q9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1913577:LPB144 RS08680
gene id: 1913577:LPB144_RS08680
uniprot id: A0A1L3J5P2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1913577:LPB144 RS03575
gene id: 1913577:LPB144_RS03575
uniprot id: A0A1L3J307
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1913577:LPB144 RS07070
gene id: 1913577:LPB144_RS07070
uniprot id: A0A1L3J8G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1913577:LPB144 RS02055
gene id: 1913577:LPB144_RS02055
uniprot id: A0A1L3J297
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1913577:LPB144 RS12605
gene id: 1913577:LPB144_RS12605
uniprot id: A0A1L3J7P9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS05905
gene id: 1913577:LPB144_RS05905
uniprot id: A0A1L3J497
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1913577:LPB144 RS09540
gene id: 1913577:LPB144_RS09540
uniprot id: A0A1L3J642
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS01575
gene id: 1913577:LPB144_RS01575
uniprot id: A0A1L3J217
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1913577:LPB144 RS02335
gene id: 1913577:LPB144_RS02335
uniprot id: A0A1L3J891
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1913577:LPB144 RS01330
gene id: 1913577:LPB144_RS01330
uniprot id: A0A1L3J1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1913577:LPB144 RS03735
gene id: 1913577:LPB144_RS03735
uniprot id: A0A1L3J336
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS01065
gene id: 1913577:LPB144_RS01065
uniprot id: A0A1L3J1T3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1913577:LPB144 RS11735
gene id: 1913577:LPB144_RS11735
uniprot id: A0A1L3J7A3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1913577:LPB144 RS01205
gene id: 1913577:LPB144_RS01205
uniprot id: A0A1L3J1V6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1913577:LPB144 RS00370
gene id: 1913577:LPB144_RS00370
uniprot id: A0A1L3J1E0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS08235
gene id: 1913577:LPB144_RS08235
uniprot id: A0A1L3J5H9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1913577:LPB144 RS13375
gene id: 1913577:LPB144_RS13375
uniprot id: A0A1L3J867
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS00645
gene id: 1913577:LPB144_RS00645
uniprot id: A0A1L3J1K3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1913577:LPB144 RS12915
gene id: 1913577:LPB144_RS12915
uniprot id: A0A1L3J7V1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1913577:LPB144 RS06090
gene id: 1913577:LPB144_RS06090
uniprot id: A0A1L3J4D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS00355
gene id: 1913577:LPB144_RS00355
uniprot id: A0A1L3J1F7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1913577:LPB144 RS13250
gene id: 1913577:LPB144_RS13250
uniprot id: A0A1L3J818
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1913577:LPB144 RS01410
gene id: 1913577:LPB144_RS01410
uniprot id: A0A1L3J1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS12755
gene id: 1913577:LPB144_RS12755
uniprot id: A0A1L3J7S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1913577:LPB144 RS12425
gene id: 1913577:LPB144_RS12425
uniprot id: A0A1L3J7N0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1913577:LPB144 RS12090
gene id: 1913577:LPB144_RS12090
uniprot id: A0A1L3J7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1913577:LPB144 RS04600
gene id: 1913577:LPB144_RS04600
uniprot id: A0A1L3J3I7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1913577:LPB144 RS09970
gene id: 1913577:LPB144_RS09970
uniprot id: A0A1L3J6B3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1913577:LPB144 RS00525
gene id: 1913577:LPB144_RS00525
uniprot id: A0A1L3J1I5
names: Similarity
messages: Belongs to the LOG family.

1913577:LPB144 RS07405
gene id: 1913577:LPB144_RS07405
uniprot id: A0A1L3J502
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1913577:LPB144 RS02825
gene id: 1913577:LPB144_RS02825
uniprot id: A0A1L3J2P7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1913577:LPB144 RS12690
gene id: 1913577:LPB144_RS12690
uniprot id: A0A1L3J7Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1913577:LPB144 RS04835
gene id: 1913577:LPB144_RS04835
uniprot id: A0A1L3J3Q3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1913577:LPB144 RS08360
gene id: 1913577:LPB144_RS08360
uniprot id: A0A1L3J5G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1913577:LPB144 RS12795
gene id: 1913577:LPB144_RS12795
uniprot id: A0A1L3J7T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1913577:LPB144 RS06520
gene id: 1913577:LPB144_RS06520
uniprot id: A0A1L3J4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS08025
gene id: 1913577:LPB144_RS08025
uniprot id: A0A1L3J5E2
names: Similarity
messages: Belongs to the fructosamine kinase family.

1913577:LPB144 RS10660
gene id: 1913577:LPB144_RS10660
uniprot id: A0A1L3J6P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1913577:LPB144 RS07875
gene id: 1913577:LPB144_RS07875
uniprot id: A0A1L3J5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1913577:LPB144 RS07490
gene id: 1913577:LPB144_RS07490
uniprot id: A0A1L3J542
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS12630
gene id: 1913577:LPB144_RS12630
uniprot id: A0A1L3J7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS04690
gene id: 1913577:LPB144_RS04690
uniprot id: A0A1L3J3K7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1913577:LPB144 RS04270
gene id: 1913577:LPB144_RS04270
uniprot id: A0A1L3J3C8
names: Similarity
messages: Belongs to the peptidase C56 family.

1913577:LPB144 RS07865
gene id: 1913577:LPB144_RS07865
uniprot id: A0A1L3J559
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1913577:LPB144 RS00710
gene id: 1913577:LPB144_RS00710
uniprot id: A0A1L3J1L7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1913577:LPB144 RS03215
gene id: 1913577:LPB144_RS03215
uniprot id: A0A1L3J2U2
names: Similarity
messages: Belongs to the ArsC family.

1913577:LPB144 RS00465
gene id: 1913577:LPB144_RS00465
uniprot id: A0A1L3J1G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1913577:LPB144 RS00325
gene id: 1913577:LPB144_RS00325
uniprot id: A0A1L3J1E9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS09390
gene id: 1913577:LPB144_RS09390
uniprot id: A0A1L3J623
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1913577:LPB144 RS05115
gene id: 1913577:LPB144_RS05115
uniprot id: A0A1L3J3U0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1913577:LPB144 RS08450
gene id: 1913577:LPB144_RS08450
uniprot id: A0A1L3J5M7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1913577:LPB144 RS01545
gene id: 1913577:LPB144_RS01545
uniprot id: A0A1L3J214
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1913577:LPB144 RS09385
gene id: 1913577:LPB144_RS09385
uniprot id: A0A1L3J615
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1913577:LPB144 RS01850
gene id: 1913577:LPB144_RS01850
uniprot id: A0A1L3J277
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1913577:LPB144 RS12765
gene id: 1913577:LPB144_RS12765
uniprot id: A0A1L3J7T7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1913577:LPB144 RS01905
gene id: 1913577:LPB144_RS01905
uniprot id: A0A1L3J290
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1913577:LPB144 RS05155
gene id: 1913577:LPB144_RS05155
uniprot id: A0A1L3J3W9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1913577:LPB144 RS06065
gene id: 1913577:LPB144_RS06065
uniprot id: A0A1L3J4C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1913577:LPB144 RS04230
gene id: 1913577:LPB144_RS04230
uniprot id: A0A1L3J3B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1913577:LPB144 RS06045
gene id: 1913577:LPB144_RS06045
uniprot id: A0A1L3J4C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1913577:LPB144 RS03935
gene id: 1913577:LPB144_RS03935
uniprot id: A0A1L3J389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1913577:LPB144 RS09590
gene id: 1913577:LPB144_RS09590
uniprot id: A0A1L3J8J5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1913577:LPB144 RS00435
gene id: 1913577:LPB144_RS00435
uniprot id: A0A1L3J1G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1913577:LPB144 RS10945
gene id: 1913577:LPB144_RS10945
uniprot id: A0A1L3J6Y1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1913577:LPB144 RS08880
gene id: 1913577:LPB144_RS08880
uniprot id: A0A1L3J5U8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS11225
gene id: 1913577:LPB144_RS11225
uniprot id: A0A1L3J6Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1913577:LPB144 RS08935
gene id: 1913577:LPB144_RS08935
uniprot id: A0A1L3J5T7
names: Similarity
messages: Belongs to the sigma-54 factor family.

1913577:LPB144 RS03325
gene id: 1913577:LPB144_RS03325
uniprot id: A0A1L3J2W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1913577:LPB144 RS09880
gene id: 1913577:LPB144_RS09880
uniprot id: A0A1L3J6C1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1913577:LPB144 RS12840
gene id: 1913577:LPB144_RS12840
uniprot id: A0A1L3J7W2
names: Similarity
messages: Belongs to the citrate synthase family.

1913577:LPB144 RS00030
gene id: 1913577:LPB144_RS00030
uniprot id: A0A1L3J876
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1913577:LPB144 RS07825
gene id: 1913577:LPB144_RS07825
uniprot id: A0A1L3J592
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1913577:LPB144 RS11375
gene id: 1913577:LPB144_RS11375
uniprot id: A0A1L3J756
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1913577:LPB144 RS09105
gene id: 1913577:LPB144_RS09105
uniprot id: A0A1L3J5W5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1913577:LPB144 RS07620
gene id: 1913577:LPB144_RS07620
uniprot id: A0A1L3J548
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1913577:LPB144 RS09760
gene id: 1913577:LPB144_RS09760
uniprot id: A0A1L3J6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1913577:LPB144 RS07340
gene id: 1913577:LPB144_RS07340
uniprot id: A0A1L3J8F5
names: Similarity
messages: Belongs to the peptidase S14 family.

1913577:LPB144 RS06925
gene id: 1913577:LPB144_RS06925
uniprot id: A0A1L3J4R7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1913577:LPB144 RS10920
gene id: 1913577:LPB144_RS10920
uniprot id: A0A1L3J6U9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1913577:LPB144 RS10130
gene id: 1913577:LPB144_RS10130
uniprot id: A0A1L3J6H6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1913577:LPB144 RS08815
gene id: 1913577:LPB144_RS08815
uniprot id: A0A1L3J5N3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS01460
gene id: 1913577:LPB144_RS01460
uniprot id: A0A1L3J215
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1913577:LPB144 RS00630
gene id: 1913577:LPB144_RS00630
uniprot id: A0A1L3J880
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS12745
gene id: 1913577:LPB144_RS12745
uniprot id: A0A1L3J7R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1913577:LPB144 RS07960
gene id: 1913577:LPB144_RS07960
uniprot id: A0A1L3J596
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1913577:LPB144 RS08460
gene id: 1913577:LPB144_RS08460
uniprot id: A0A1L3J5K1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913577:LPB144 RS02570
gene id: 1913577:LPB144_RS02570
uniprot id: A0A1L3J2L7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1913577:LPB144 RS02200
gene id: 1913577:LPB144_RS02200
uniprot id: A0A1L3J2E0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1913577:LPB144 RS11785
gene id: 1913577:LPB144_RS11785
uniprot id: A0A1L3J798
names: Similarity
messages: Belongs to the thioredoxin family.

1913577:LPB144 RS11640
gene id: 1913577:LPB144_RS11640
uniprot id: A0A1L3J795
names: Similarity
messages: Belongs to the UPF0045 family.

1913577:LPB144 RS01620
gene id: 1913577:LPB144_RS01620
uniprot id: A0A1L3J227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS13035
gene id: 1913577:LPB144_RS13035
uniprot id: A0A1L3J7X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1913577:LPB144 RS07545
gene id: 1913577:LPB144_RS07545
uniprot id: A0A1L3J552
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1913577:LPB144 RS05145
gene id: 1913577:LPB144_RS05145
uniprot id: A0A1L3J3X2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1913577:LPB144 RS00235
gene id: 1913577:LPB144_RS00235
uniprot id: A0A1L3J1D1
names: Subcellular Location Annotation
messages: Mitochondrion

1913577:LPB144 RS08200
gene id: 1913577:LPB144_RS08200
uniprot id: A0A1L3J5D1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1913577:LPB144 RS00625
gene id: 1913577:LPB144_RS00625
uniprot id: A0A1L3J1K2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1913577:LPB144 RS08320
gene id: 1913577:LPB144_RS08320
uniprot id: A0A1L3J5H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1913577:LPB144 RS09235
gene id: 1913577:LPB144_RS09235
uniprot id: A0A1L3J5Z3
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1913577:LPB144 RS08690
gene id: 1913577:LPB144_RS08690
uniprot id: A0A1L3J5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1913577:LPB144 RS05575
gene id: 1913577:LPB144_RS05575
uniprot id: A0A1L3J411
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1913577:LPB144 RS07575
gene id: 1913577:LPB144_RS07575
uniprot id: A0A1L3J506
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1913577:LPB144 RS05480
gene id: 1913577:LPB144_RS05480
uniprot id: A0A1L3J409
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1913577:LPB144 RS04480
gene id: 1913577:LPB144_RS04480
uniprot id: A0A1L3J3I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS13015
gene id: 1913577:LPB144_RS13015
uniprot id: A0A1L3J7W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS03895
gene id: 1913577:LPB144_RS03895
uniprot id: A0A1L3J371
names: Subcellular Location Annotation
messages: Cytoplasm

1913577:LPB144 RS03890
gene id: 1913577:LPB144_RS03890
uniprot id: A0A1L3J363
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS00520
gene id: 1913577:LPB144_RS00520
uniprot id: A0A1L3J1H2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1913577:LPB144 RS13470
gene id: 1913577:LPB144_RS13470
uniprot id: A0A1L3J853
names: Similarity
messages: Belongs to the nitroreductase family.

1913577:LPB144 RS05025
gene id: 1913577:LPB144_RS05025
uniprot id: A0A1L3J3R9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS04915
gene id: 1913577:LPB144_RS04915
uniprot id: A0A1L3J3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1913577:LPB144 RS08210
gene id: 1913577:LPB144_RS08210
uniprot id: A0A1L3J5H2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS01615
gene id: 1913577:LPB144_RS01615
uniprot id: A0A1L3J8B4
names: Similarity
messages: Belongs to the SusD family.

1913577:LPB144 RS11470
gene id: 1913577:LPB144_RS11470
uniprot id: A0A1L3J728
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS11750
gene id: 1913577:LPB144_RS11750
uniprot id: A0A1L3J7B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

1913577:LPB144 RS04630
gene id: 1913577:LPB144_RS04630
uniprot id: A0A1L3J3L0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS11755
gene id: 1913577:LPB144_RS11755
uniprot id: A0A1L3J780
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1913577:LPB144 RS12975
gene id: 1913577:LPB144_RS12975
uniprot id: A0A1L3J7W8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1913577:LPB144 RS06300
gene id: 1913577:LPB144_RS06300
uniprot id: A0A1L3J4H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1913577:LPB144 RS10300
gene id: 1913577:LPB144_RS10300
uniprot id: A0A1L3J6I1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1913577:LPB144 RS10545
gene id: 1913577:LPB144_RS10545
uniprot id: A0A1L3J6N3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1913577:LPB144 RS03500
gene id: 1913577:LPB144_RS03500
uniprot id: A0A1L3J2Z4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1913577:LPB144 RS11325
gene id: 1913577:LPB144_RS11325
uniprot id: A0A1L3J746
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1913577:LPB144 RS09910
gene id: 1913577:LPB144_RS09910
uniprot id: A0A1L3J6D4
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1913577:LPB144 RS00150
gene id: 1913577:LPB144_RS00150
uniprot id: A0A1L3J1B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1913577:LPB144 RS07530
gene id: 1913577:LPB144_RS07530
uniprot id: A0A1L3J545
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1913577:LPB144 RS10665
gene id: 1913577:LPB144_RS10665
uniprot id: A0A1L3J6Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1913577:LPB144 RS00360
gene id: 1913577:LPB144_RS00360
uniprot id: A0A1L3J1F8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1913577:LPB144 RS07130
gene id: 1913577:LPB144_RS07130
uniprot id: A0A1L3J8H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1913577:LPB144 RS04640
gene id: 1913577:LPB144_RS04640
uniprot id: A0A1L3J3L5
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1913577:LPB144 RS08370
gene id: 1913577:LPB144_RS08370
uniprot id: A0A1L3J5J8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1913577:LPB144 RS02730
gene id: 1913577:LPB144_RS02730
uniprot id: A0A1L3J2N3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1913577:LPB144 RS13080
gene id: 1913577:LPB144_RS13080
uniprot id: A0A1L3J7Y6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1913577:LPB144 RS03180
gene id: 1913577:LPB144_RS03180
uniprot id: A0A1L3J2T5
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1913577:LPB144 RS06690
gene id: 1913577:LPB144_RS06690
uniprot id: A0A1L3J4Q9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1913577:LPB144 RS11150
gene id: 1913577:LPB144_RS11150
uniprot id: A0A1L3J705
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1913577:LPB144 RS08930
gene id: 1913577:LPB144_RS08930
uniprot id: A0A1L3J5V7
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

1913577:LPB144 RS11300
gene id: 1913577:LPB144_RS11300
uniprot id: A0A1L3J723
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1913577:LPB144 RS11030
gene id: 1913577:LPB144_RS11030
uniprot id: A0A1L3J6Y7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1913577:LPB144 RS12940
gene id: 1913577:LPB144_RS12940
uniprot id: A0A1L3J7Y0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS07920
gene id: 1913577:LPB144_RS07920
uniprot id: A0A1L3J5B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1913577:LPB144 RS13005
gene id: 1913577:LPB144_RS13005
uniprot id: A0A1L3J7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1913577:LPB144 RS01180
gene id: 1913577:LPB144_RS01180
uniprot id: A0A1L3J1V9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1913577:LPB144 RS07085
gene id: 1913577:LPB144_RS07085
uniprot id: A0A1L3J4X6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1913577:LPB144 RS00770
gene id: 1913577:LPB144_RS00770
uniprot id: A0A1L3J1M9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS07735
gene id: 1913577:LPB144_RS07735
uniprot id: A0A1L3J557
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1913577:LPB144 RS01015
gene id: 1913577:LPB144_RS01015
uniprot id: A0A1L3J1S9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1913577:LPB144 RS12720
gene id: 1913577:LPB144_RS12720
uniprot id: A0A1L3J7T5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1913577:LPB144 RS07730
gene id: 1913577:LPB144_RS07730
uniprot id: A0A1L3J589
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS13310
gene id: 1913577:LPB144_RS13310
uniprot id: A0A1L3J848
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1913577:LPB144 RS12785
gene id: 1913577:LPB144_RS12785
uniprot id: A0A1L3J7V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1913577:LPB144 RS04275
gene id: 1913577:LPB144_RS04275
uniprot id: A0A1L3J3E2
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS09885
gene id: 1913577:LPB144_RS09885
uniprot id: A0A1L3J699
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1913577:LPB144 RS03905
gene id: 1913577:LPB144_RS03905
uniprot id: A0A1L3J371
names: Subcellular Location Annotation
messages: Cytoplasm

1913577:LPB144 RS13435
gene id: 1913577:LPB144_RS13435
uniprot id: A0A1L3J875
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1913577:LPB144 RS09605
gene id: 1913577:LPB144_RS09605
uniprot id: A0A1L3J671
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1913577:LPB144 RS08540
gene id: 1913577:LPB144_RS08540
uniprot id: A0A1L3J5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1913577:LPB144 RS03495
gene id: 1913577:LPB144_RS03495
uniprot id: A0A1L3J300
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1913577:LPB144 RS03170
gene id: 1913577:LPB144_RS03170
uniprot id: A0A1L3J2S6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1913577:LPB144 RS06535
gene id: 1913577:LPB144_RS06535
uniprot id: A0A1L3J4J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1913577:LPB144 RS10425
gene id: 1913577:LPB144_RS10425
uniprot id: A0A1L3J6J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1913577:LPB144 RS08755
gene id: 1913577:LPB144_RS08755
uniprot id: A0A1L3J5M9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1913577:LPB144 RS09685
gene id: 1913577:LPB144_RS09685
uniprot id: A0A1L3J644
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS06735
gene id: 1913577:LPB144_RS06735
uniprot id: A0A1L3J4P5
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS00155
gene id: 1913577:LPB144_RS00155
uniprot id: A0A1L3J1B1
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1913577:LPB144 RS10230
gene id: 1913577:LPB144_RS10230
uniprot id: A0A1L3J6E5
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1913577:LPB144 RS13065
gene id: 1913577:LPB144_RS13065
uniprot id: A0A1L3J7X8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS08405
gene id: 1913577:LPB144_RS08405
uniprot id: A0A1L3J5I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1913577:LPB144 RS04635
gene id: 1913577:LPB144_RS04635
uniprot id: A0A1L3J3J9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1913577:LPB144 RS12735
gene id: 1913577:LPB144_RS12735
uniprot id: A0A1L3J7U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1913577:LPB144 RS12010
gene id: 1913577:LPB144_RS12010
uniprot id: A0A1L3J7D2
names: Similarity
messages: Belongs to the SusD family.

1913577:LPB144 RS09495
gene id: 1913577:LPB144_RS09495
uniprot id: A0A1L3J637
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS10430
gene id: 1913577:LPB144_RS10430
uniprot id: A0A1L3J6L4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS06550
gene id: 1913577:LPB144_RS06550
uniprot id: A0A1L3J4L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1913577:LPB144 RS10450
gene id: 1913577:LPB144_RS10450
uniprot id: A0A1L3J6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1913577:LPB144 RS03425
gene id: 1913577:LPB144_RS03425
uniprot id: A0A1L3J2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1913577:LPB144 RS10115
gene id: 1913577:LPB144_RS10115
uniprot id: A0A1L3J6E8
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1913577:LPB144 RS00960
gene id: 1913577:LPB144_RS00960
uniprot id: A0A1L3J1R5
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS07780
gene id: 1913577:LPB144_RS07780
uniprot id: A0A1L3J599
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1913577:LPB144 RS06015
gene id: 1913577:LPB144_RS06015
uniprot id: A0A1L3J4C0
names: Similarity
messages: Belongs to the CinA family.

1913577:LPB144 RS00585
gene id: 1913577:LPB144_RS00585
uniprot id: A0A1L3J1K0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1913577:LPB144 RS09595
gene id: 1913577:LPB144_RS09595
uniprot id: A0A1L3J651
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS11385
gene id: 1913577:LPB144_RS11385
uniprot id: A0A1L3J719
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1913577:LPB144 RS04210
gene id: 1913577:LPB144_RS04210
uniprot id: A0A1L3J8B9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1913577:LPB144 RS11535
gene id: 1913577:LPB144_RS11535
uniprot id: A0A1L3J787
names: Subcellular Location Annotation
messages: Cytoplasm

1913577:LPB144 RS10575
gene id: 1913577:LPB144_RS10575
uniprot id: A0A1L3J6M8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1913577:LPB144 RS10555
gene id: 1913577:LPB144_RS10555
uniprot id: A0A1L3J6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1913577:LPB144 RS05020
gene id: 1913577:LPB144_RS05020
uniprot id: A0A1L3J3R6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1913577:LPB144 RS12810
gene id: 1913577:LPB144_RS12810
uniprot id: A0A1L3J7T9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1913577:LPB144 RS05380
gene id: 1913577:LPB144_RS05380
uniprot id: A0A1L3J410
names: Similarity
messages: Belongs to the AHA1 family.

1913577:LPB144 RS13445
gene id: 1913577:LPB144_RS13445
uniprot id: A0A1L3J850
names: Similarity
messages: Belongs to the TrpC family.

1913577:LPB144 RS02780
gene id: 1913577:LPB144_RS02780
uniprot id: A0A1L3J2P5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS13120
gene id: 1913577:LPB144_RS13120
uniprot id: A0A1L3J7Y5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1913577:LPB144 RS01335
gene id: 1913577:LPB144_RS01335
uniprot id: A0A1L3J1X7
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1913577:LPB144 RS01670
gene id: 1913577:LPB144_RS01670
uniprot id: A0A1L3J237
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1913577:LPB144 RS01845
gene id: 1913577:LPB144_RS01845
uniprot id: A0A1L3J256
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1913577:LPB144 RS12510
gene id: 1913577:LPB144_RS12510
uniprot id: A0A1L3J7P3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS05310
gene id: 1913577:LPB144_RS05310
uniprot id: A0A1L3J3X8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS07325
gene id: 1913577:LPB144_RS07325
uniprot id: A0A1L3J4Z1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS02085
gene id: 1913577:LPB144_RS02085
uniprot id: A0A1L3J2C8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS12200
gene id: 1913577:LPB144_RS12200
uniprot id: A0A1L3J7G3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1913577:LPB144 RS10155
gene id: 1913577:LPB144_RS10155
uniprot id: A0A1L3J6H8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS04545
gene id: 1913577:LPB144_RS04545
uniprot id: A0A1L3J8C4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS03370
gene id: 1913577:LPB144_RS03370
uniprot id: A0A1L3J2X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1913577:LPB144 RS11485
gene id: 1913577:LPB144_RS11485
uniprot id: A0A1L3J777
names: Similarity
messages: Belongs to the histone deacetylase family.

1913577:LPB144 RS09585
gene id: 1913577:LPB144_RS09585
uniprot id: A0A1L3J678
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1913577:LPB144 RS12890
gene id: 1913577:LPB144_RS12890
uniprot id: A0A1L3J7X0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1913577:LPB144 RS12775
gene id: 1913577:LPB144_RS12775
uniprot id: A0A1L3J7R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1913577:LPB144 RS10065
gene id: 1913577:LPB144_RS10065
uniprot id: A0A1L3J6D8
names: Similarity
messages: Belongs to the ArsC family.

1913577:LPB144 RS06200
gene id: 1913577:LPB144_RS06200
uniprot id: A0A1L3J4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1913577:LPB144 RS03280
gene id: 1913577:LPB144_RS03280
uniprot id: A0A1L3J2U5
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS12160
gene id: 1913577:LPB144_RS12160
uniprot id: A0A1L3J7J9
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS00160
gene id: 1913577:LPB144_RS00160
uniprot id: A0A1L3J1B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1913577:LPB144 RS07800
gene id: 1913577:LPB144_RS07800
uniprot id: A0A1L3J563
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS11690
gene id: 1913577:LPB144_RS11690
uniprot id: A0A1L3J797
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1913577:LPB144 RS01380
gene id: 1913577:LPB144_RS01380
uniprot id: A0A1L3J1X6
names: Similarity
messages: Belongs to the AHA1 family.

1913577:LPB144 RS12935
gene id: 1913577:LPB144_RS12935
uniprot id: A0A1L3J7W5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1913577:LPB144 RS03345
gene id: 1913577:LPB144_RS03345
uniprot id: A0A1L3J2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1913577:LPB144 RS05655
gene id: 1913577:LPB144_RS05655
uniprot id: A0A1L3J435
names: Similarity
messages: Belongs to the AHA1 family.

1913577:LPB144 RS05000
gene id: 1913577:LPB144_RS05000
uniprot id: A0A1L3J3T6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1913577:LPB144 RS06425
gene id: 1913577:LPB144_RS06425
uniprot id: A0A1L3J4H6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1913577:LPB144 RS06220
gene id: 1913577:LPB144_RS06220
uniprot id: A0A1L3J4F1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1913577:LPB144 RS07940
gene id: 1913577:LPB144_RS07940
uniprot id: A0A1L3J5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1913577:LPB144 RS06560
gene id: 1913577:LPB144_RS06560
uniprot id: A0A1L3J4N8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1913577:LPB144 RS12945
gene id: 1913577:LPB144_RS12945
uniprot id: A0A1L3J7U3
names: Similarity
messages: Belongs to the NAD synthetase family.

1913577:LPB144 RS12435
gene id: 1913577:LPB144_RS12435
uniprot id: A0A1L3J7L3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1913577:LPB144 RS08660
gene id: 1913577:LPB144_RS08660
uniprot id: A0A1L3J5P5
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1913577:LPB144 RS03750
gene id: 1913577:LPB144_RS03750
uniprot id: A0A1L3J337
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1913577:LPB144 RS12515
gene id: 1913577:LPB144_RS12515
uniprot id: A0A1L3J7Q0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1913577:LPB144 RS13115
gene id: 1913577:LPB144_RS13115
uniprot id: A0A1L3J7Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1913577:LPB144 RS10885
gene id: 1913577:LPB144_RS10885
uniprot id: A0A1L3J6S1
names: Similarity
messages: Belongs to the DprA/Smf family.

1913577:LPB144 RS13485
gene id: 1913577:LPB144_RS13485
uniprot id: A0A1L3J843
names: Similarity
messages: Belongs to the peptidase S8 family.

1913577:LPB144 RS06295
gene id: 1913577:LPB144_RS06295
uniprot id: A0A1L3J4F8
names: Similarity
messages: Belongs to the UPF0173 family.

1913577:LPB144 RS04135
gene id: 1913577:LPB144_RS04135
uniprot id: A0A1L3J3A0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS09370
gene id: 1913577:LPB144_RS09370
uniprot id: A0A1L3J5Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1913577:LPB144 RS07785
gene id: 1913577:LPB144_RS07785
uniprot id: A0A1L3J566
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1913577:LPB144 RS00995
gene id: 1913577:LPB144_RS00995
uniprot id: A0A1L3J884
names: Similarity
messages: Belongs to the arginase family.

1913577:LPB144 RS01500
gene id: 1913577:LPB144_RS01500
uniprot id: A0A1L3J213
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1913577:LPB144 RS09175
gene id: 1913577:LPB144_RS09175
uniprot id: A0A1L3J5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1913577:LPB144 RS02505
gene id: 1913577:LPB144_RS02505
uniprot id: A0A1L3J2K1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS06130
gene id: 1913577:LPB144_RS06130
uniprot id: A0A1L3J4B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1913577:LPB144 RS12000
gene id: 1913577:LPB144_RS12000
uniprot id: A0A1L3J7H2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1913577:LPB144 RS13105
gene id: 1913577:LPB144_RS13105
uniprot id: A0A1L3J813
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1913577:LPB144 RS03870
gene id: 1913577:LPB144_RS03870
uniprot id: A0A1L3J348
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1913577:LPB144 RS08670
gene id: 1913577:LPB144_RS08670
uniprot id: A0A1L3J5R2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1913577:LPB144 RS08925
gene id: 1913577:LPB144_RS08925
uniprot id: A0A1L3J5Q9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1913577:LPB144 RS10890
gene id: 1913577:LPB144_RS10890
uniprot id: A0A1L3J6X1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1913577:LPB144 RS08920
gene id: 1913577:LPB144_RS08920
uniprot id: A0A1L3J5Q8
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS02080
gene id: 1913577:LPB144_RS02080
uniprot id: A0A1L3J2C0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1913577:LPB144 RS08455
gene id: 1913577:LPB144_RS08455
uniprot id: A0A1L3J5I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1913577:LPB144 RS12805
gene id: 1913577:LPB144_RS12805
uniprot id: A0A1L3J7S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1913577:LPB144 RS04285
gene id: 1913577:LPB144_RS04285
uniprot id: A0A1L3J3D9
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1913577:LPB144 RS04710
gene id: 1913577:LPB144_RS04710
uniprot id: A0A1L3J3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1913577:LPB144 RS01210
gene id: 1913577:LPB144_RS01210
uniprot id: A0A1L3J1U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1913577:LPB144 RS04245
gene id: 1913577:LPB144_RS04245
uniprot id: A0A1L3J3E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1913577:LPB144 RS12195
gene id: 1913577:LPB144_RS12195
uniprot id: A0A1L3J7K2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1913577:LPB144 RS10280
gene id: 1913577:LPB144_RS10280
uniprot id: A0A1L3J6F6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1913577:LPB144 RS10895
gene id: 1913577:LPB144_RS10895
uniprot id: A0A1L3J6W7
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1913577:LPB144 RS01265
gene id: 1913577:LPB144_RS01265
uniprot id: A0A1L3J1V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1913577:LPB144 RS08950
gene id: 1913577:LPB144_RS08950
uniprot id: A0A1L3J5W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1913577:LPB144 RS12780
gene id: 1913577:LPB144_RS12780
uniprot id: A0A1L3J7V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1913577:LPB144 RS01730
gene id: 1913577:LPB144_RS01730
uniprot id: A0A1L3J262
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1913577:LPB144 RS07415
gene id: 1913577:LPB144_RS07415
uniprot id: A0A1L3J4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1913577:LPB144 RS00185
gene id: 1913577:LPB144_RS00185
uniprot id: A0A1L3J1C7
names: Subcellular Location Annotation
messages: Membrane

1913577:LPB144 RS04080
gene id: 1913577:LPB144_RS04080
uniprot id: A0A1L3J387
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1913577:LPB144 RS08480
gene id: 1913577:LPB144_RS08480
uniprot id: A0A1L3J5M8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1913577:LPB144 RS07695
gene id: 1913577:LPB144_RS07695
uniprot id: A0A1L3J527
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1913577:LPB144 RS09230
gene id: 1913577:LPB144_RS09230
uniprot id: A0A1L3J5Y0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.