1912795:BK816 RS04940
gene id: 1912795:BK816_RS04940
uniprot id: A0A1D9MKK6
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS07515
gene id: 1912795:BK816_RS07515
uniprot id: A0A1D9MLU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1912795:BK816 RS02260
gene id: 1912795:BK816_RS02260
uniprot id: A0A1D9MIY7
names: Similarity
messages: Belongs to the UPF0237 family.

1912795:BK816 RS07495
gene id: 1912795:BK816_RS07495
uniprot id: A0A1D9MLK4
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1912795:BK816 RS05290
gene id: 1912795:BK816_RS05290
uniprot id: A0A1D9MKM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1912795:BK816 RS00485
gene id: 1912795:BK816_RS00485
uniprot id: A0A1D9MI46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS08835
gene id: 1912795:BK816_RS08835
uniprot id: A0A1D9MM42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1912795:BK816 RS02845
gene id: 1912795:BK816_RS02845
uniprot id: A0A1D9MJI0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1912795:BK816 RS04225
gene id: 1912795:BK816_RS04225
uniprot id: A0A1D9MK54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1912795:BK816 RS05190
gene id: 1912795:BK816_RS05190
uniprot id: A0A1D9MK83
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1912795:BK816 RS00665
gene id: 1912795:BK816_RS00665
uniprot id: A0A1D9MIF2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1912795:BK816 RS05125
gene id: 1912795:BK816_RS05125
uniprot id: A0A1D9MK74
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

1912795:BK816 RS04220
gene id: 1912795:BK816_RS04220
uniprot id: A0A1D9MJX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1912795:BK816 RS04635
gene id: 1912795:BK816_RS04635
uniprot id: A0A1D9MK35
names: Similarity
messages: Belongs to the FemABX family.

1912795:BK816 RS02225
gene id: 1912795:BK816_RS02225
uniprot id: A0A1D9MJA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1912795:BK816 RS08670
gene id: 1912795:BK816_RS08670
uniprot id: A0A1D9MM26
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS05790
gene id: 1912795:BK816_RS05790
uniprot id: A0A1D9MKP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1912795:BK816 RS02905
gene id: 1912795:BK816_RS02905
uniprot id: A0A1D9MJ96
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1912795:BK816 RS08900
gene id: 1912795:BK816_RS08900
uniprot id: A0A1D9MM66
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1912795:BK816 RS06815
gene id: 1912795:BK816_RS06815
uniprot id: A0A1D9ML57
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1912795:BK816 RS08915
gene id: 1912795:BK816_RS08915
uniprot id: A0A1D9MMA7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1912795:BK816 RS00935
gene id: 1912795:BK816_RS00935
uniprot id: A0A1D9MIA4
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS02715
gene id: 1912795:BK816_RS02715
uniprot id: A0A1D9MJ83
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1912795:BK816 RS03670
gene id: 1912795:BK816_RS03670
uniprot id: A0A1D9MJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1912795:BK816 RS07475
gene id: 1912795:BK816_RS07475
uniprot id: A0A1D9MLB0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1912795:BK816 RS08020
gene id: 1912795:BK816_RS08020
uniprot id: A0A1D9MLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1912795:BK816 RS04980
gene id: 1912795:BK816_RS04980
uniprot id: A0A1D9MKB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1912795:BK816 RS05800
gene id: 1912795:BK816_RS05800
uniprot id: A0A1D9MKM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1912795:BK816 RS01345
gene id: 1912795:BK816_RS01345
uniprot id: A0A1D9MII2
names: Similarity
messages: Belongs to the GARS family.

1912795:BK816 RS05225
gene id: 1912795:BK816_RS05225
uniprot id: A0A1D9MKD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1912795:BK816 RS05255
gene id: 1912795:BK816_RS05255
uniprot id: A0A1D9MKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1912795:BK816 RS04310
gene id: 1912795:BK816_RS04310
uniprot id: A0A1D9MJY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1912795:BK816 RS06480
gene id: 1912795:BK816_RS06480
uniprot id: A0A1D9ML65
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1912795:BK816 RS01975
gene id: 1912795:BK816_RS01975
uniprot id: A0A1D9MIP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1912795:BK816 RS05210
gene id: 1912795:BK816_RS05210
uniprot id: A0A1D9MKC4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1912795:BK816 RS04655
gene id: 1912795:BK816_RS04655
uniprot id: A0A1D9MKC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1912795:BK816 RS06565
gene id: 1912795:BK816_RS06565
uniprot id: A0A1D9MKV3
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1912795:BK816 RS08840
gene id: 1912795:BK816_RS08840
uniprot id: A0A1D9MMH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1912795:BK816 RS05955
gene id: 1912795:BK816_RS05955
uniprot id: A0A1D9MKT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1912795:BK816 RS04880
gene id: 1912795:BK816_RS04880
uniprot id: A0A1D9MKF8
names: Similarity
messages: Belongs to the UPF0371 family.

1912795:BK816 RS08775
gene id: 1912795:BK816_RS08775
uniprot id: A0A1D9MLV3
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1912795:BK816 RS02945
gene id: 1912795:BK816_RS02945
uniprot id: A0A1D9MJ59
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1912795:BK816 RS05235
gene id: 1912795:BK816_RS05235
uniprot id: A0A1D9MKQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS02065
gene id: 1912795:BK816_RS02065
uniprot id: A0A1D9MJ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1912795:BK816 RS08220
gene id: 1912795:BK816_RS08220
uniprot id: A0A1D9MM48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1912795:BK816 RS05155
gene id: 1912795:BK816_RS05155
uniprot id: A0A1D9MKE6
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS01365
gene id: 1912795:BK816_RS01365
uniprot id: A0A1D9MIF0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1912795:BK816 RS01795
gene id: 1912795:BK816_RS01795
uniprot id: A0A1D9MIR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1912795:BK816 RS05285
gene id: 1912795:BK816_RS05285
uniprot id: A0A1D9MKE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1912795:BK816 RS02085
gene id: 1912795:BK816_RS02085
uniprot id: A0A1D9MJ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1912795:BK816 RS04145
gene id: 1912795:BK816_RS04145
uniprot id: A0A1D9MK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1912795:BK816 RS02500
gene id: 1912795:BK816_RS02500
uniprot id: A0A1D9MJF0
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1912795:BK816 RS04270
gene id: 1912795:BK816_RS04270
uniprot id: A0A1D9MJY0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1912795:BK816 RS02050
gene id: 1912795:BK816_RS02050
uniprot id: A0A1D9MIW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1912795:BK816 RS08355
gene id: 1912795:BK816_RS08355
uniprot id: A0A1D9MMN2
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS05175
gene id: 1912795:BK816_RS05175
uniprot id: A0A1D9MKT0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1912795:BK816 RS04075
gene id: 1912795:BK816_RS04075
uniprot id: A0A1D9MK63
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1912795:BK816 RS06270
gene id: 1912795:BK816_RS06270
uniprot id: A0A1D9MMJ8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1912795:BK816 RS02755
gene id: 1912795:BK816_RS02755
uniprot id: A0A1D9MJI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1912795:BK816 RS02055
gene id: 1912795:BK816_RS02055
uniprot id: A0A1D9MIU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1912795:BK816 RS06085
gene id: 1912795:BK816_RS06085
uniprot id: A0A1D9ML67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1912795:BK816 RS01425
gene id: 1912795:BK816_RS01425
uniprot id: A0A1D9MIU1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1912795:BK816 RS03690
gene id: 1912795:BK816_RS03690
uniprot id: A0A1D9MJZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane

1912795:BK816 RS07385
gene id: 1912795:BK816_RS07385
uniprot id: A0A1D9MLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS06650
gene id: 1912795:BK816_RS06650
uniprot id: A0A1D9ML41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS01920
gene id: 1912795:BK816_RS01920
uniprot id: A0A1D9MIN3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1912795:BK816 RS06595
gene id: 1912795:BK816_RS06595
uniprot id: A0A1D9ML06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1912795:BK816 RS07995
gene id: 1912795:BK816_RS07995
uniprot id: A0A1D9MLQ6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1912795:BK816 RS02305
gene id: 1912795:BK816_RS02305
uniprot id: A0A1D9MIZ0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS03265
gene id: 1912795:BK816_RS03265
uniprot id: A0A1D9MJT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS01815
gene id: 1912795:BK816_RS01815
uniprot id: A0A1D9MIQ4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1912795:BK816 RS03600
gene id: 1912795:BK816_RS03600
uniprot id: A0A1D9MJH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1912795:BK816 RS03595
gene id: 1912795:BK816_RS03595
uniprot id: A0A1D9MJY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1912795:BK816 RS06965
gene id: 1912795:BK816_RS06965
uniprot id: A0A1D9MLN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1912795:BK816 RS04505
gene id: 1912795:BK816_RS04505
uniprot id: A0A1D9MK17
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1912795:BK816 RS03220
gene id: 1912795:BK816_RS03220
uniprot id: A0A1D9MMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1912795:BK816 RS05660
gene id: 1912795:BK816_RS05660
uniprot id: A0A1D9MKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1912795:BK816 RS06440
gene id: 1912795:BK816_RS06440
uniprot id: A0A1D9MLD7
names: Similarity
messages: Belongs to the peptidase C40 family.

1912795:BK816 RS04350
gene id: 1912795:BK816_RS04350
uniprot id: A0A1D9MK11
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1912795:BK816 RS06060
gene id: 1912795:BK816_RS06060
uniprot id: A0A1D9MKZ4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1912795:BK816 RS07235
gene id: 1912795:BK816_RS07235
uniprot id: A0A1D9MLK0
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1912795:BK816 RS07755
gene id: 1912795:BK816_RS07755
uniprot id: A0A1D9MLM5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1912795:BK816 RS02025
gene id: 1912795:BK816_RS02025
uniprot id: A0A1D9MIQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1912795:BK816 RS07925
gene id: 1912795:BK816_RS07925
uniprot id: A0A1D9MM29
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1912795:BK816 RS06840
gene id: 1912795:BK816_RS06840
uniprot id: A0A1D9ML58
names: Similarity
messages: Belongs to the WXG100 family.

1912795:BK816 RS05010
gene id: 1912795:BK816_RS05010
uniprot id: A0A1D9MK53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1912795:BK816 RS04165
gene id: 1912795:BK816_RS04165
uniprot id: A0A1D9MJX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1912795:BK816 RS05965
gene id: 1912795:BK816_RS05965
uniprot id: A0A1D9MKQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1912795:BK816 RS07850
gene id: 1912795:BK816_RS07850
uniprot id: A0A1D9MLR1
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1912795:BK816 RS01475
gene id: 1912795:BK816_RS01475
uniprot id: A0A1D9MIU9
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1912795:BK816 RS05270
gene id: 1912795:BK816_RS05270
uniprot id: A0A1D9MKE9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1912795:BK816 RS00360
gene id: 1912795:BK816_RS00360
uniprot id: A0A1D9MHZ1
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS03270
gene id: 1912795:BK816_RS03270
uniprot id: A0A1D9MJA9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1912795:BK816 RS02915
gene id: 1912795:BK816_RS02915
uniprot id: A0A1D9MJL4
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1912795:BK816 RS04665
gene id: 1912795:BK816_RS04665
uniprot id: A0A1D9MKH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS02850
gene id: 1912795:BK816_RS02850
uniprot id: A0A1D9MMA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS03470
gene id: 1912795:BK816_RS03470
uniprot id: A0A1D9MJV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1912795:BK816 RS03675
gene id: 1912795:BK816_RS03675
uniprot id: A0A1D9MJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1912795:BK816 RS02960
gene id: 1912795:BK816_RS02960
uniprot id: A0A1D9MJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS02640
gene id: 1912795:BK816_RS02640
uniprot id: A0A1D9MJ69
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1912795:BK816 RS02205
gene id: 1912795:BK816_RS02205
uniprot id: A0A1D9MIX7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1912795:BK816 RS07685
gene id: 1912795:BK816_RS07685
uniprot id: A0A1D9MM18
names: Similarity
messages: Belongs to the peptidase C40 family.

1912795:BK816 RS04190
gene id: 1912795:BK816_RS04190
uniprot id: A0A1D9MJS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1912795:BK816 RS03680
gene id: 1912795:BK816_RS03680
uniprot id: A0A1D9MJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1912795:BK816 RS04545
gene id: 1912795:BK816_RS04545
uniprot id: A0A1D9MK26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1912795:BK816 RS05120
gene id: 1912795:BK816_RS05120
uniprot id: A0A1D9MKR9
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1912795:BK816 RS02665
gene id: 1912795:BK816_RS02665
uniprot id: A0A1D9MJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1912795:BK816 RS04470
gene id: 1912795:BK816_RS04470
uniprot id: A0A1D9MKD7
names: Similarity
messages: Belongs to the peptidase M1 family.

1912795:BK816 RS06445
gene id: 1912795:BK816_RS06445
uniprot id: A0A1D9MKT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1912795:BK816 RS01930
gene id: 1912795:BK816_RS01930
uniprot id: A0A1D9MJ35
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1912795:BK816 RS03155
gene id: 1912795:BK816_RS03155
uniprot id: A0A1D9MJE8
names: Similarity
messages: Belongs to the FGGY kinase family.

1912795:BK816 RS02540
gene id: 1912795:BK816_RS02540
uniprot id: A0A1D9MJ57
names: Similarity
messages: Belongs to the peptidase M24B family.

1912795:BK816 RS04430
gene id: 1912795:BK816_RS04430
uniprot id: A0A1D9MK30
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS03685
gene id: 1912795:BK816_RS03685
uniprot id: A0A1D9MJW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1912795:BK816 RS08380
gene id: 1912795:BK816_RS08380
uniprot id: A0A1D9MLN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1912795:BK816 RS08335
gene id: 1912795:BK816_RS08335
uniprot id: A0A1D9MLX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1912795:BK816 RS06495
gene id: 1912795:BK816_RS06495
uniprot id: A0A1D9MMB8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1912795:BK816 RS03140
gene id: 1912795:BK816_RS03140
uniprot id: A0A1D9MMQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1912795:BK816 RS04335
gene id: 1912795:BK816_RS04335
uniprot id: A0A1D9MKA9
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1912795:BK816 RS02110
gene id: 1912795:BK816_RS02110
uniprot id: A0A1D9MJ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1912795:BK816 RS01690
gene id: 1912795:BK816_RS01690
uniprot id: A0A1D9MIY4
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS02465
gene id: 1912795:BK816_RS02465
uniprot id: A0A1D9MJ41
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1912795:BK816 RS08960
gene id: 1912795:BK816_RS08960
uniprot id: A0A1D9MMJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1912795:BK816 RS02275
gene id: 1912795:BK816_RS02275
uniprot id: A0A1D9MJB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS04180
gene id: 1912795:BK816_RS04180
uniprot id: A0A1D9MK81
names: Similarity
messages: Belongs to the glutamine synthetase family.

1912795:BK816 RS07660
gene id: 1912795:BK816_RS07660
uniprot id: A0A1D9MLN1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1912795:BK816 RS06630
gene id: 1912795:BK816_RS06630
uniprot id: A0A1D9ML33
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1912795:BK816 RS04215
gene id: 1912795:BK816_RS04215
uniprot id: A0A1D9MJY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1912795:BK816 RS00285
gene id: 1912795:BK816_RS00285
uniprot id: A0A1D9MIA5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1912795:BK816 RS02805
gene id: 1912795:BK816_RS02805
uniprot id: A0A1D9MJJ8
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS01545
gene id: 1912795:BK816_RS01545
uniprot id: A0A1D9MIY0
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1912795:BK816 RS04895
gene id: 1912795:BK816_RS04895
uniprot id: A0A1D9MKM3
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1912795:BK816 RS06975
gene id: 1912795:BK816_RS06975
uniprot id: A0A1D9ML89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1912795:BK816 RS01720
gene id: 1912795:BK816_RS01720
uniprot id: A0A1D9MIQ8
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS03520
gene id: 1912795:BK816_RS03520
uniprot id: A0A1D9MJT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1912795:BK816 RS05820
gene id: 1912795:BK816_RS05820
uniprot id: A0A1D9ML42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1912795:BK816 RS02095
gene id: 1912795:BK816_RS02095
uniprot id: A0A1D9MIV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1912795:BK816 RS05785
gene id: 1912795:BK816_RS05785
uniprot id: A0A1D9MKM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1912795:BK816 RS02080
gene id: 1912795:BK816_RS02080
uniprot id: A0A1D9MIW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1912795:BK816 RS06140
gene id: 1912795:BK816_RS06140
uniprot id: A0A1D9MKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1912795:BK816 RS06510
gene id: 1912795:BK816_RS06510
uniprot id: A0A1D9ML16
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1912795:BK816 RS08325
gene id: 1912795:BK816_RS08325
uniprot id: A0A1D9MM89
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1912795:BK816 RS02310
gene id: 1912795:BK816_RS02310
uniprot id: A0A1D9MJ16
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1912795:BK816 RS06170
gene id: 1912795:BK816_RS06170
uniprot id: A0A1D9MKT9
names: Similarity
messages: Belongs to the UPF0145 family.

1912795:BK816 RS06030
gene id: 1912795:BK816_RS06030
uniprot id: A0A1D9MKR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1912795:BK816 RS07770
gene id: 1912795:BK816_RS07770
uniprot id: A0A1D9MLM3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1912795:BK816 RS05560
gene id: 1912795:BK816_RS05560
uniprot id: A0A1D9MKI8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1912795:BK816 RS02605
gene id: 1912795:BK816_RS02605
uniprot id: A0A1D9MJ67
names: Similarity
messages: Belongs to the GSP E family.

1912795:BK816 RS05340
gene id: 1912795:BK816_RS05340
uniprot id: A0A1D9MKN3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1912795:BK816 RS02070
gene id: 1912795:BK816_RS02070
uniprot id: A0A1D9MJ77
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1912795:BK816 RS04325
gene id: 1912795:BK816_RS04325
uniprot id: A0A1D9MJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1912795:BK816 RS06865
gene id: 1912795:BK816_RS06865
uniprot id: A0A1D9ML66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS02750
gene id: 1912795:BK816_RS02750
uniprot id: A0A1D9MJ90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1912795:BK816 RS08905
gene id: 1912795:BK816_RS08905
uniprot id: A0A1D9MM51
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS04760
gene id: 1912795:BK816_RS04760
uniprot id: A0A1D9MK78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1912795:BK816 RS03250
gene id: 1912795:BK816_RS03250
uniprot id: A0A1D9MJE7
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1912795:BK816 RS02410
gene id: 1912795:BK816_RS02410
uniprot id: A0A1D9MJ19
names: Similarity
messages: Belongs to the peptidase S66 family.

1912795:BK816 RS06810
gene id: 1912795:BK816_RS06810
uniprot id: A0A1D9MKY3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1912795:BK816 RS05360
gene id: 1912795:BK816_RS05360
uniprot id: A0A1D9MKI9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1912795:BK816 RS07510
gene id: 1912795:BK816_RS07510
uniprot id: A0A1D9MLP3
names: Similarity
messages: Belongs to the peptidase S1C family.

1912795:BK816 RS01295
gene id: 1912795:BK816_RS01295
uniprot id: A0A1D9MIH3
names: Similarity
messages: Belongs to the thioredoxin family.

1912795:BK816 RS04870
gene id: 1912795:BK816_RS04870
uniprot id: A0A1D9MK96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1912795:BK816 RS07435
gene id: 1912795:BK816_RS07435
uniprot id: A0A1D9MLV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1912795:BK816 RS04210
gene id: 1912795:BK816_RS04210
uniprot id: A0A1D9MJW4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1912795:BK816 RS08330
gene id: 1912795:BK816_RS08330
uniprot id: A0A1D9MLV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1912795:BK816 RS07620
gene id: 1912795:BK816_RS07620
uniprot id: A0A1D9MLK1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1912795:BK816 RS06305
gene id: 1912795:BK816_RS06305
uniprot id: A0A1D9ML80
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS03135
gene id: 1912795:BK816_RS03135
uniprot id: A0A1D9MJR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1912795:BK816 RS02535
gene id: 1912795:BK816_RS02535
uniprot id: A0A1D9MJ30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

1912795:BK816 RS06950
gene id: 1912795:BK816_RS06950
uniprot id: A0A1D9ML86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1912795:BK816 RS06915
gene id: 1912795:BK816_RS06915
uniprot id: A0A1D9MLL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1912795:BK816 RS01905
gene id: 1912795:BK816_RS01905
uniprot id: A0A1D9MJ43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1912795:BK816 RS09595
gene id: 1912795:BK816_RS09595
uniprot id: A0A1D9MHW7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1912795:BK816 RS03865
gene id: 1912795:BK816_RS03865
uniprot id: A0A1D9MK29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1912795:BK816 RS09645
gene id: 1912795:BK816_RS09645
uniprot id: A0A1D9MK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1912795:BK816 RS06580
gene id: 1912795:BK816_RS06580
uniprot id: A0A1D9ML07
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS02105
gene id: 1912795:BK816_RS02105
uniprot id: A0A1D9MIV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1912795:BK816 RS02165
gene id: 1912795:BK816_RS02165
uniprot id: A0A1D9MJ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1912795:BK816 RS02970
gene id: 1912795:BK816_RS02970
uniprot id: A0A1D9MJA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1912795:BK816 RS06505
gene id: 1912795:BK816_RS06505
uniprot id: A0A1D9MKU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1912795:BK816 RS04020
gene id: 1912795:BK816_RS04020
uniprot id: A0A1D9MJT7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1912795:BK816 RS02900
gene id: 1912795:BK816_RS02900
uniprot id: A0A1D9MJB3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1912795:BK816 RS03760
gene id: 1912795:BK816_RS03760
uniprot id: A0A1D9MJK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1912795:BK816 RS06575
gene id: 1912795:BK816_RS06575
uniprot id: A0A1D9MLE2
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS05470
gene id: 1912795:BK816_RS05470
uniprot id: A0A1D9MKK8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1912795:BK816 RS02035
gene id: 1912795:BK816_RS02035
uniprot id: A0A1D9MJ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1912795:BK816 RS01955
gene id: 1912795:BK816_RS01955
uniprot id: A0A1D9MIS4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1912795:BK816 RS00625
gene id: 1912795:BK816_RS00625
uniprot id: A0A1D9MIG2
names: Similarity
messages: Belongs to the GSP E family.

1912795:BK816 RS03735
gene id: 1912795:BK816_RS03735
uniprot id: A0A1D9MJX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1912795:BK816 RS04100
gene id: 1912795:BK816_RS04100
uniprot id: A0A1D9MMT5
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1912795:BK816 RS04375
gene id: 1912795:BK816_RS04375
uniprot id: A0A1D9MK00
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS03740
gene id: 1912795:BK816_RS03740
uniprot id: A0A1D9MMD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1912795:BK816 RS05380
gene id: 1912795:BK816_RS05380
uniprot id: A0A1D9MKH2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1912795:BK816 RS04060
gene id: 1912795:BK816_RS04060
uniprot id: A0A1D9MJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1912795:BK816 RS09770
gene id: 1912795:BK816_RS09770
uniprot id: A0A1D9MLB8
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1912795:BK816 RS03085
gene id: 1912795:BK816_RS03085
uniprot id: A0A1D9MJP1
names: Similarity
messages: Belongs to the peptidase M13 family.

1912795:BK816 RS03095
gene id: 1912795:BK816_RS03095
uniprot id: A0A1D9MMC4
names: Similarity
messages: Belongs to the IMPACT family.

1912795:BK816 RS04315
gene id: 1912795:BK816_RS04315
uniprot id: A0A1D9MJY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1912795:BK816 RS06095
gene id: 1912795:BK816_RS06095
uniprot id: A0A1D9MKV5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1912795:BK816 RS00725
gene id: 1912795:BK816_RS00725
uniprot id: A0A1D9MII3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS00780
gene id: 1912795:BK816_RS00780
uniprot id: A0A1D9MIJ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1912795:BK816 RS03240
gene id: 1912795:BK816_RS03240
uniprot id: A0A1D9MJG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS03570
gene id: 1912795:BK816_RS03570
uniprot id: A0A1D9MJM5
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS04080
gene id: 1912795:BK816_RS04080
uniprot id: A0A1D9MJU7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1912795:BK816 RS06195
gene id: 1912795:BK816_RS06195
uniprot id: A0A1D9MKW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1912795:BK816 RS05885
gene id: 1912795:BK816_RS05885
uniprot id: A0A1D9ML19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1912795:BK816 RS04875
gene id: 1912795:BK816_RS04875
uniprot id: A0A1D9MK76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1912795:BK816 RS06770
gene id: 1912795:BK816_RS06770
uniprot id: A0A1D9ML55
names: Similarity
messages: Belongs to the TPP enzyme family.

1912795:BK816 RS02505
gene id: 1912795:BK816_RS02505
uniprot id: A0A1D9MJF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1912795:BK816 RS03275
gene id: 1912795:BK816_RS03275
uniprot id: A0A1D9MJG9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1912795:BK816 RS00605
gene id: 1912795:BK816_RS00605
uniprot id: A0A1D9MI71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1912795:BK816 RS02735
gene id: 1912795:BK816_RS02735
uniprot id: A0A1D9MJJ4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1912795:BK816 RS01430
gene id: 1912795:BK816_RS01430
uniprot id: A0A1D9MIV4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1912795:BK816 RS01880
gene id: 1912795:BK816_RS01880
uniprot id: A0A1D9MIR4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS02875
gene id: 1912795:BK816_RS02875
uniprot id: A0A1D9MJA8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1912795:BK816 RS03050
gene id: 1912795:BK816_RS03050
uniprot id: A0A1D9MJB8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1912795:BK816 RS01820
gene id: 1912795:BK816_RS01820
uniprot id: A0A1D9MJ02
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1912795:BK816 RS03565
gene id: 1912795:BK816_RS03565
uniprot id: A0A1D9MJK0
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS06400
gene id: 1912795:BK816_RS06400
uniprot id: A0A1D9ML05
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1912795:BK816 RS04990
gene id: 1912795:BK816_RS04990
uniprot id: A0A1D9MK92
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1912795:BK816 RS07675
gene id: 1912795:BK816_RS07675
uniprot id: A0A1D9MLS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1912795:BK816 RS05265
gene id: 1912795:BK816_RS05265
uniprot id: A0A1D9MKD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1912795:BK816 RS06065
gene id: 1912795:BK816_RS06065
uniprot id: A0A1D9ML43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1912795:BK816 RS04480
gene id: 1912795:BK816_RS04480
uniprot id: A0A1D9MK13
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1912795:BK816 RS01360
gene id: 1912795:BK816_RS01360
uniprot id: A0A1D9MIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1912795:BK816 RS06450
gene id: 1912795:BK816_RS06450
uniprot id: A0A1D9ML10
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS06820
gene id: 1912795:BK816_RS06820
uniprot id: A0A1D9MLJ2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1912795:BK816 RS01510
gene id: 1912795:BK816_RS01510
uniprot id: A0A1D9MIK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1912795:BK816 RS00165
gene id: 1912795:BK816_RS00165
uniprot id: A0A1D9MI07
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1912795:BK816 RS08445
gene id: 1912795:BK816_RS08445
uniprot id: A0A1D9MLP2
names: Similarity
messages: Belongs to the HisA/HisF family.

1912795:BK816 RS00255
gene id: 1912795:BK816_RS00255
uniprot id: A0A1D9MHZ7
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS05135
gene id: 1912795:BK816_RS05135
uniprot id: A0A1D9MKQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1912795:BK816 RS08015
gene id: 1912795:BK816_RS08015
uniprot id: A0A1D9MLQ7
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1912795:BK816 RS03755
gene id: 1912795:BK816_RS03755
uniprot id: A0A1D9MK21
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1912795:BK816 RS00160
gene id: 1912795:BK816_RS00160
uniprot id: A0A1D9MHW5
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1912795:BK816 RS08405
gene id: 1912795:BK816_RS08405
uniprot id: A0A1D9MLY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

1912795:BK816 RS05845
gene id: 1912795:BK816_RS05845
uniprot id: A0A1D9ML28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1912795:BK816 RS04425
gene id: 1912795:BK816_RS04425
uniprot id: A0A1D9MK06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS02130
gene id: 1912795:BK816_RS02130
uniprot id: A0A1D9MIX8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1912795:BK816 RS00505
gene id: 1912795:BK816_RS00505
uniprot id: A0A1D9MIC6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1912795:BK816 RS03540
gene id: 1912795:BK816_RS03540
uniprot id: A0A1D9MM54
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1912795:BK816 RS01800
gene id: 1912795:BK816_RS01800
uniprot id: A0A1D9MIP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1912795:BK816 RS02145
gene id: 1912795:BK816_RS02145
uniprot id: A0A1D9MIW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1912795:BK816 RS08010
gene id: 1912795:BK816_RS08010
uniprot id: A0A1D9MLR4
names: Subcellular Location Annotation
messages: Cytoplasm

1912795:BK816 RS06645
gene id: 1912795:BK816_RS06645
uniprot id: A0A1D9ML53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1912795:BK816 RS08385
gene id: 1912795:BK816_RS08385
uniprot id: A0A1D9MLX3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1912795:BK816 RS00875
gene id: 1912795:BK816_RS00875
uniprot id: A0A1D9MIA6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1912795:BK816 RS04230
gene id: 1912795:BK816_RS04230
uniprot id: A0A1D9MK90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1912795:BK816 RS03645
gene id: 1912795:BK816_RS03645
uniprot id: A0A1D9MJZ9
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS02615
gene id: 1912795:BK816_RS02615
uniprot id: A0A1D9MJE2
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS03120
gene id: 1912795:BK816_RS03120
uniprot id: A0A1D9MJC9
names: Similarity
messages: Belongs to the arginase family.

1912795:BK816 RS04195
gene id: 1912795:BK816_RS04195
uniprot id: A0A1D9MJY1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1912795:BK816 RS04490
gene id: 1912795:BK816_RS04490
uniprot id: A0A1D9MMD9
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1912795:BK816 RS00065
gene id: 1912795:BK816_RS00065
uniprot id: A0A1D9MI52
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1912795:BK816 RS06160
gene id: 1912795:BK816_RS06160
uniprot id: A0A1D9MKX1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1912795:BK816 RS05495
gene id: 1912795:BK816_RS05495
uniprot id: A0A1D9MKK4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1912795:BK816 RS01040
gene id: 1912795:BK816_RS01040
uniprot id: A0A1D9MM97
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1912795:BK816 RS06310
gene id: 1912795:BK816_RS06310
uniprot id: A0A1D9MLB5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1912795:BK816 RS05680
gene id: 1912795:BK816_RS05680
uniprot id: A0A1D9MKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS08280
gene id: 1912795:BK816_RS08280
uniprot id: A0A1D9MLV1
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS01290
gene id: 1912795:BK816_RS01290
uniprot id: A0A1D9MIJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS02460
gene id: 1912795:BK816_RS02460
uniprot id: A0A1D9MIY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1912795:BK816 RS05705
gene id: 1912795:BK816_RS05705
uniprot id: A0A1D9MKH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1912795:BK816 RS03165
gene id: 1912795:BK816_RS03165
uniprot id: A0A1D9MJE1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS05220
gene id: 1912795:BK816_RS05220
uniprot id: A0A1D9MKF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1912795:BK816 RS07555
gene id: 1912795:BK816_RS07555
uniprot id: A0A1D9MLJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1912795:BK816 RS02320
gene id: 1912795:BK816_RS02320
uniprot id: A0A1D9MJ91
names: Similarity
messages: Belongs to the PspA/IM30 family.

1912795:BK816 RS01275
gene id: 1912795:BK816_RS01275
uniprot id: A0A1D9MIH7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1912795:BK816 RS00660
gene id: 1912795:BK816_RS00660
uniprot id: A0A1D9MI61
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1912795:BK816 RS06955
gene id: 1912795:BK816_RS06955
uniprot id: A0A1D9MLF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1912795:BK816 RS02115
gene id: 1912795:BK816_RS02115
uniprot id: A0A1D9MJ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1912795:BK816 RS07430
gene id: 1912795:BK816_RS07430
uniprot id: A0A1D9MLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1912795:BK816 RS06315
gene id: 1912795:BK816_RS06315
uniprot id: A0A1D9MKS7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1912795:BK816 RS06655
gene id: 1912795:BK816_RS06655
uniprot id: A0A1D9ML17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1912795:BK816 RS07285
gene id: 1912795:BK816_RS07285
uniprot id: A0A1D9MLK9
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

1912795:BK816 RS06775
gene id: 1912795:BK816_RS06775
uniprot id: A0A1D9ML49
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1912795:BK816 RS05500
gene id: 1912795:BK816_RS05500
uniprot id: A0A1D9MKH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS05365
gene id: 1912795:BK816_RS05365
uniprot id: A0A1D9MKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1912795:BK816 RS07740
gene id: 1912795:BK816_RS07740
uniprot id: A0A1D9MM31
names: Similarity
messages: Belongs to the Dps family.

1912795:BK816 RS03905
gene id: 1912795:BK816_RS03905
uniprot id: A0A1D9MJR6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1912795:BK816 RS07975
gene id: 1912795:BK816_RS07975
uniprot id: A0A1D9MMY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS08140
gene id: 1912795:BK816_RS08140
uniprot id: A0A1D9MLS7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1912795:BK816 RS06680
gene id: 1912795:BK816_RS06680
uniprot id: A0A1D9ML39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1912795:BK816 RS00895
gene id: 1912795:BK816_RS00895
uniprot id: A0A1D9MIJ1
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS04590
gene id: 1912795:BK816_RS04590
uniprot id: A0A1D9MMQ1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS01865
gene id: 1912795:BK816_RS01865
uniprot id: A0A1D9MM24
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1912795:BK816 RS01995
gene id: 1912795:BK816_RS01995
uniprot id: A0A1D9MIS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1912795:BK816 RS00315
gene id: 1912795:BK816_RS00315
uniprot id: A0A1D9MI91
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1912795:BK816 RS02195
gene id: 1912795:BK816_RS02195
uniprot id: A0A1D9MIX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1912795:BK816 RS03630
gene id: 1912795:BK816_RS03630
uniprot id: A0A1D9MJL7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1912795:BK816 RS08420
gene id: 1912795:BK816_RS08420
uniprot id: A0A1D9MM28
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

1912795:BK816 RS05620
gene id: 1912795:BK816_RS05620
uniprot id: A0A1D9MKS9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1912795:BK816 RS04275
gene id: 1912795:BK816_RS04275
uniprot id: A0A1D9MK61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1912795:BK816 RS07585
gene id: 1912795:BK816_RS07585
uniprot id: A0A1D9MLJ9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1912795:BK816 RS07545
gene id: 1912795:BK816_RS07545
uniprot id: A0A1D9MLI8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS07400
gene id: 1912795:BK816_RS07400
uniprot id: A0A1D9MMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1912795:BK816 RS04560
gene id: 1912795:BK816_RS04560
uniprot id: A0A1D9MKB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1912795:BK816 RS06115
gene id: 1912795:BK816_RS06115
uniprot id: A0A1D9ML52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS02020
gene id: 1912795:BK816_RS02020
uniprot id: A0A1D9MJ65
names: Similarity
messages: Belongs to the CapA family.

1912795:BK816 RS02575
gene id: 1912795:BK816_RS02575
uniprot id: A0A1D9MJG4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1912795:BK816 RS03770
gene id: 1912795:BK816_RS03770
uniprot id: A0A1D9MK15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS08600
gene id: 1912795:BK816_RS08600
uniprot id: A0A1D9MM58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1912795:BK816 RS02040
gene id: 1912795:BK816_RS02040
uniprot id: A0A1D9MIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1912795:BK816 RS08830
gene id: 1912795:BK816_RS08830
uniprot id: A0A1D9MLW1
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS01805
gene id: 1912795:BK816_RS01805
uniprot id: A0A1D9MME5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1912795:BK816 RS02150
gene id: 1912795:BK816_RS02150
uniprot id: A0A1D9MIY8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1912795:BK816 RS04495
gene id: 1912795:BK816_RS04495
uniprot id: A0A1D9MMJ3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1912795:BK816 RS04240
gene id: 1912795:BK816_RS04240
uniprot id: A0A1D9MJS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1912795:BK816 RS00050
gene id: 1912795:BK816_RS00050
uniprot id: A0A1D9MKS7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1912795:BK816 RS00785
gene id: 1912795:BK816_RS00785
uniprot id: A0A1D9MI58
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS04185
gene id: 1912795:BK816_RS04185
uniprot id: A0A1D9MK95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1912795:BK816 RS09000
gene id: 1912795:BK816_RS09000
uniprot id: A0A1D9MMB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1912795:BK816 RS07760
gene id: 1912795:BK816_RS07760
uniprot id: A0A1D9MML6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1912795:BK816 RS08930
gene id: 1912795:BK816_RS08930
uniprot id: A0A1D9MN13
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1912795:BK816 RS04285
gene id: 1912795:BK816_RS04285
uniprot id: A0A1D9MKB8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1912795:BK816 RS01450
gene id: 1912795:BK816_RS01450
uniprot id: A0A1D9MIV5
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS03090
gene id: 1912795:BK816_RS03090
uniprot id: A0A1D9MJD0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1912795:BK816 RS08360
gene id: 1912795:BK816_RS08360
uniprot id: A0A1D9MLV4
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

1912795:BK816 RS04900
gene id: 1912795:BK816_RS04900
uniprot id: A0A1D9MK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1912795:BK816 RS05590
gene id: 1912795:BK816_RS05590
uniprot id: A0A1D9MKM6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1912795:BK816 RS06785
gene id: 1912795:BK816_RS06785
uniprot id: A0A1D9MLG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1912795:BK816 RS00220
gene id: 1912795:BK816_RS00220
uniprot id: A0A1D9MHY5
names: Similarity
messages: Belongs to the peptidase C59 family.

1912795:BK816 RS05345
gene id: 1912795:BK816_RS05345
uniprot id: A0A1D9MKS7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1912795:BK816 RS05930
gene id: 1912795:BK816_RS05930
uniprot id: A0A1D9MKX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1912795:BK816 RS06845
gene id: 1912795:BK816_RS06845
uniprot id: A0A1D9MLC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1912795:BK816 RS06660
gene id: 1912795:BK816_RS06660
uniprot id: A0A1D9ML94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1912795:BK816 RS06050
gene id: 1912795:BK816_RS06050
uniprot id: A0A1D9MKR6
names: Similarity
messages: Belongs to the Fur family.

1912795:BK816 RS08460
gene id: 1912795:BK816_RS08460
uniprot id: A0A1D9MLY1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1912795:BK816 RS04520
gene id: 1912795:BK816_RS04520
uniprot id: A0A1D9MKF6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1912795:BK816 RS02155
gene id: 1912795:BK816_RS02155
uniprot id: A0A1D9MIW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1912795:BK816 RS02045
gene id: 1912795:BK816_RS02045
uniprot id: A0A1D9MIU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1912795:BK816 RS03875
gene id: 1912795:BK816_RS03875
uniprot id: A0A1D9MJM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1912795:BK816 RS04765
gene id: 1912795:BK816_RS04765
uniprot id: A0A1D9MK57
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1912795:BK816 RS03360
gene id: 1912795:BK816_RS03360
uniprot id: A0A1D9MJR0
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1912795:BK816 RS05585
gene id: 1912795:BK816_RS05585
uniprot id: A0A1D9MKF3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1912795:BK816 RS01715
gene id: 1912795:BK816_RS01715
uniprot id: A0A1D9MIK7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1912795:BK816 RS01625
gene id: 1912795:BK816_RS01625
uniprot id: A0A1D9MIP7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1912795:BK816 RS04735
gene id: 1912795:BK816_RS04735
uniprot id: A0A1D9MK02
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1912795:BK816 RS04365
gene id: 1912795:BK816_RS04365
uniprot id: A0A1D9MJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1912795:BK816 RS03765
gene id: 1912795:BK816_RS03765
uniprot id: A0A1D9MJQ7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1912795:BK816 RS00080
gene id: 1912795:BK816_RS00080
uniprot id: A0A1D9MHU3
names: Similarity
messages: Belongs to the UPF0749 family.

1912795:BK816 RS00025
gene id: 1912795:BK816_RS00025
uniprot id: A0A1D9MHU6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1912795:BK816 RS01550
gene id: 1912795:BK816_RS01550
uniprot id: A0A1D9MIH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1912795:BK816 RS06435
gene id: 1912795:BK816_RS06435
uniprot id: A0A1D9MLA3
names: Similarity
messages: Belongs to the universal stress protein A family.

1912795:BK816 RS08860
gene id: 1912795:BK816_RS08860
uniprot id: A0A1D9MM36
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1912795:BK816 RS08090
gene id: 1912795:BK816_RS08090
uniprot id: A0A1D9MLX8
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS00330
gene id: 1912795:BK816_RS00330
uniprot id: A0A1D9MI28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1912795:BK816 RS07440
gene id: 1912795:BK816_RS07440
uniprot id: A0A1D9MLG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1912795:BK816 RS02175
gene id: 1912795:BK816_RS02175
uniprot id: A0A1D9MIT4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1912795:BK816 RS04525
gene id: 1912795:BK816_RS04525
uniprot id: A0A1D9MJX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1912795:BK816 RS03850
gene id: 1912795:BK816_RS03850
uniprot id: A0A1D9MJS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1912795:BK816 RS07365
gene id: 1912795:BK816_RS07365
uniprot id: A0A1D9ML90
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS05405
gene id: 1912795:BK816_RS05405
uniprot id: A0A1D9MKX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1912795:BK816 RS04170
gene id: 1912795:BK816_RS04170
uniprot id: A0A1D9MJV9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1912795:BK816 RS06075
gene id: 1912795:BK816_RS06075
uniprot id: A0A1D9MKN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1912795:BK816 RS08055
gene id: 1912795:BK816_RS08055
uniprot id: A0A1D9MLR9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1912795:BK816 RS08685
gene id: 1912795:BK816_RS08685
uniprot id: A0A1D9MM69
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1912795:BK816 RS05455
gene id: 1912795:BK816_RS05455
uniprot id: A0A1D9MKU6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1912795:BK816 RS02610
gene id: 1912795:BK816_RS02610
uniprot id: A0A1D9MJ46
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS00750
gene id: 1912795:BK816_RS00750
uniprot id: A0A1D9MI87
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1912795:BK816 RS03705
gene id: 1912795:BK816_RS03705
uniprot id: A0A1D9MJP6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1912795:BK816 RS03835
gene id: 1912795:BK816_RS03835
uniprot id: A0A1D9MK25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane

1912795:BK816 RS06215
gene id: 1912795:BK816_RS06215
uniprot id: A0A1D9MKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS02840
gene id: 1912795:BK816_RS02840
uniprot id: A0A1D9MJ86
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1912795:BK816 RS02360
gene id: 1912795:BK816_RS02360
uniprot id: A0A1D9MJ27
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1912795:BK816 RS05840
gene id: 1912795:BK816_RS05840
uniprot id: A0A1D9MKR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1912795:BK816 RS02795
gene id: 1912795:BK816_RS02795
uniprot id: A0A1D9MJ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1912795:BK816 RS02140
gene id: 1912795:BK816_RS02140
uniprot id: A0A1D9MIX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1912795:BK816 RS05130
gene id: 1912795:BK816_RS05130
uniprot id: A0A1D9MKE4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1912795:BK816 RS04550
gene id: 1912795:BK816_RS04550
uniprot id: A0A1D9MK48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1912795:BK816 RS03970
gene id: 1912795:BK816_RS03970
uniprot id: A0A1D9MJU3
names: Similarity
messages: Belongs to the prokaryotic ubiquitin-like protein family.

1912795:BK816 RS00075
gene id: 1912795:BK816_RS00075
uniprot id: A0A1D9MI63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1912795:BK816 RS04460
gene id: 1912795:BK816_RS04460
uniprot id: A0A1D9MJW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1912795:BK816 RS00010
gene id: 1912795:BK816_RS00010
uniprot id: A0A1D9MI57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1912795:BK816 RS03285
gene id: 1912795:BK816_RS03285
uniprot id: A0A1D9MJS5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1912795:BK816 RS06330
gene id: 1912795:BK816_RS06330
uniprot id: A0A1D9MKW3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1912795:BK816 RS07910
gene id: 1912795:BK816_RS07910
uniprot id: A0A1D9MM50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1912795:BK816 RS00105
gene id: 1912795:BK816_RS00105
uniprot id: A0A1D9MHV5
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS02100
gene id: 1912795:BK816_RS02100
uniprot id: A0A1D9MIX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1912795:BK816 RS05880
gene id: 1912795:BK816_RS05880
uniprot id: A0A1D9MKW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1912795:BK816 RS05075
gene id: 1912795:BK816_RS05075
uniprot id: A0A1D9MK65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1912795:BK816 RS01855
gene id: 1912795:BK816_RS01855
uniprot id: A0A1D9MJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1912795:BK816 RS06940
gene id: 1912795:BK816_RS06940
uniprot id: A0A1D9MLA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1912795:BK816 RS00755
gene id: 1912795:BK816_RS00755
uniprot id: A0A1D9MI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1912795:BK816 RS06935
gene id: 1912795:BK816_RS06935
uniprot id: A0A1D9ML71
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1912795:BK816 RS06900
gene id: 1912795:BK816_RS06900
uniprot id: A0A1D9ML68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1912795:BK816 RS03810
gene id: 1912795:BK816_RS03810
uniprot id: A0A1D9MJY4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS07635
gene id: 1912795:BK816_RS07635
uniprot id: A0A1D9MM09
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

1912795:BK816 RS05390
gene id: 1912795:BK816_RS05390
uniprot id: A0A1D9MKG0
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS05335
gene id: 1912795:BK816_RS05335
uniprot id: A0A1D9MKF2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1912795:BK816 RS07355
gene id: 1912795:BK816_RS07355
uniprot id: A0A1D9MLV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1912795:BK816 RS08965
gene id: 1912795:BK816_RS08965
uniprot id: A0A1D9MM65
names: Similarity
messages: Belongs to the ParB family.

1912795:BK816 RS07395
gene id: 1912795:BK816_RS07395
uniprot id: A0A1D9MLG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1912795:BK816 RS01960
gene id: 1912795:BK816_RS01960
uniprot id: A0A1D9MJ21
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1912795:BK816 RS03940
gene id: 1912795:BK816_RS03940
uniprot id: A0A1D9MK44
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS01810
gene id: 1912795:BK816_RS01810
uniprot id: A0A1D9MIS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1912795:BK816 RS04030
gene id: 1912795:BK816_RS04030
uniprot id: A0A1D9MJV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1912795:BK816 RS03525
gene id: 1912795:BK816_RS03525
uniprot id: A0A1D9MJW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1912795:BK816 RS02160
gene id: 1912795:BK816_RS02160
uniprot id: A0A1D9MJ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1912795:BK816 RS02595
gene id: 1912795:BK816_RS02595
uniprot id: A0A1D9MJ48
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1912795:BK816 RS03340
gene id: 1912795:BK816_RS03340
uniprot id: A0A1D9MJH3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1912795:BK816 RS04040
gene id: 1912795:BK816_RS04040
uniprot id: A0A1D9MK22
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1912795:BK816 RS05540
gene id: 1912795:BK816_RS05540
uniprot id: A0A1D9MKX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1912795:BK816 RS02895
gene id: 1912795:BK816_RS02895
uniprot id: A0A1D9MJ97
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1912795:BK816 RS04200
gene id: 1912795:BK816_RS04200
uniprot id: A0A1D9MK86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1912795:BK816 RS08100
gene id: 1912795:BK816_RS08100
uniprot id: A0A1D9MM82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1912795:BK816 RS08855
gene id: 1912795:BK816_RS08855
uniprot id: A0A1D9MM41
names: Similarity
messages: Belongs to the DNA photolyase family.

1912795:BK816 RS05760
gene id: 1912795:BK816_RS05760
uniprot id: A0A1D9ML36
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS01045
gene id: 1912795:BK816_RS01045
uniprot id: A0A1D9MID1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

1912795:BK816 RS06090
gene id: 1912795:BK816_RS06090
uniprot id: A0A1D9MKS5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1912795:BK816 RS03885
gene id: 1912795:BK816_RS03885
uniprot id: A0A1D9MK33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1912795:BK816 RS03305
gene id: 1912795:BK816_RS03305
uniprot id: A0A1D9MJF7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1912795:BK816 RS05575
gene id: 1912795:BK816_RS05575
uniprot id: A0A1D9ML09
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1912795:BK816 RS03745
gene id: 1912795:BK816_RS03745
uniprot id: A0A1D9MK07
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1912795:BK816 RS03185
gene id: 1912795:BK816_RS03185
uniprot id: A0A1D9MJD7
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1912795:BK816 RS06690
gene id: 1912795:BK816_RS06690
uniprot id: A0A1D9ML27
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1912795:BK816 RS02740
gene id: 1912795:BK816_RS02740
uniprot id: A0A1D9MMP5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1912795:BK816 RS05315
gene id: 1912795:BK816_RS05315
uniprot id: A0A1D9MKT3
names: Similarity
messages: Belongs to the UPF0098 family.

1912795:BK816 RS06670
gene id: 1912795:BK816_RS06670
uniprot id: A0A1D9MLH7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1912795:BK816 RS04860
gene id: 1912795:BK816_RS04860
uniprot id: A0A1D9MK69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1912795:BK816 RS04250
gene id: 1912795:BK816_RS04250
uniprot id: A0A1D9MK98
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS06275
gene id: 1912795:BK816_RS06275
uniprot id: A0A1D9MKV4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1912795:BK816 RS05675
gene id: 1912795:BK816_RS05675
uniprot id: A0A1D9MKK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1912795:BK816 RS08705
gene id: 1912795:BK816_RS08705
uniprot id: A0A1D9MMQ4
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS03845
gene id: 1912795:BK816_RS03845
uniprot id: A0A1D9MJQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1912795:BK816 RS07055
gene id: 1912795:BK816_RS07055
uniprot id: A0A1D9MLB2
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS06970
gene id: 1912795:BK816_RS06970
uniprot id: A0A1D9ML13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1912795:BK816 RS03880
gene id: 1912795:BK816_RS03880
uniprot id: A0A1D9MJT0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1912795:BK816 RS02365
gene id: 1912795:BK816_RS02365
uniprot id: A0A1D9MJ08
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1912795:BK816 RS08260
gene id: 1912795:BK816_RS08260
uniprot id: A0A1D9MLV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS02000
gene id: 1912795:BK816_RS02000
uniprot id: A0A1D9MIV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1912795:BK816 RS01270
gene id: 1912795:BK816_RS01270
uniprot id: A0A1D9MIS5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1912795:BK816 RS00670
gene id: 1912795:BK816_RS00670
uniprot id: A0A1D9MIG6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1912795:BK816 RS01950
gene id: 1912795:BK816_RS01950
uniprot id: A0A1D9MIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1912795:BK816 RS04630
gene id: 1912795:BK816_RS04630
uniprot id: A0A1D9MK32
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1912795:BK816 RS07570
gene id: 1912795:BK816_RS07570
uniprot id: A0A1D9MLV6
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS05630
gene id: 1912795:BK816_RS05630
uniprot id: A0A1D9MKX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1912795:BK816 RS06385
gene id: 1912795:BK816_RS06385
uniprot id: A0A1D9MLB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS04435
gene id: 1912795:BK816_RS04435
uniprot id: A0A1D9MK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1912795:BK816 RS07965
gene id: 1912795:BK816_RS07965
uniprot id: A0A1D9MMS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1912795:BK816 RS04380
gene id: 1912795:BK816_RS04380
uniprot id: A0A1D9MK80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1912795:BK816 RS09540
gene id: 1912795:BK816_RS09540
uniprot id: A0A1D9MIJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1912795:BK816 RS03840
gene id: 1912795:BK816_RS03840
uniprot id: A0A1D9MJQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1912795:BK816 RS01435
gene id: 1912795:BK816_RS01435
uniprot id: A0A1D9MIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS06560
gene id: 1912795:BK816_RS06560
uniprot id: A0A1D9MLF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS03900
gene id: 1912795:BK816_RS03900
uniprot id: A0A1D9MJT3
names: Similarity
messages: Belongs to the UPF0102 family.

1912795:BK816 RS04255
gene id: 1912795:BK816_RS04255
uniprot id: A0A1D9MJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1912795:BK816 RS01980
gene id: 1912795:BK816_RS01980
uniprot id: A0A1D9MIU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1912795:BK816 RS00900
gene id: 1912795:BK816_RS00900
uniprot id: A0A1D9MIK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1912795:BK816 RS04555
gene id: 1912795:BK816_RS04555
uniprot id: A0A1D9MK27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1912795:BK816 RS08755
gene id: 1912795:BK816_RS08755
uniprot id: A0A1D9MM79
names: Similarity
messages: Belongs to the asp23 family.

1912795:BK816 RS04330
gene id: 1912795:BK816_RS04330
uniprot id: A0A1D9MK70
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1912795:BK816 RS05015
gene id: 1912795:BK816_RS05015
uniprot id: A0A1D9MKC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1912795:BK816 RS06375
gene id: 1912795:BK816_RS06375
uniprot id: A0A1D9MKS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1912795:BK816 RS06320
gene id: 1912795:BK816_RS06320
uniprot id: A0A1D9MKY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1912795:BK816 RS06365
gene id: 1912795:BK816_RS06365
uniprot id: A0A1D9ML92
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1912795:BK816 RS05755
gene id: 1912795:BK816_RS05755
uniprot id: A0A1D9MKZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1912795:BK816 RS02135
gene id: 1912795:BK816_RS02135
uniprot id: A0A1D9MJ76
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1912795:BK816 RS03415
gene id: 1912795:BK816_RS03415
uniprot id: A0A1D9MJR8
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS06285
gene id: 1912795:BK816_RS06285
uniprot id: A0A1D9MKY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1912795:BK816 RS08810
gene id: 1912795:BK816_RS08810
uniprot id: A0A1D9MM27
names: Subcellular Location Annotation
messages: Cell membrane

1912795:BK816 RS01355
gene id: 1912795:BK816_RS01355
uniprot id: A0A1D9MIU6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1912795:BK816 RS02030
gene id: 1912795:BK816_RS02030
uniprot id: A0A1D9MIV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1912795:BK816 RS00325
gene id: 1912795:BK816_RS00325
uniprot id: A0A1D9MHZ2
names: Similarity
messages: Belongs to the peptidase S33 family.

1912795:BK816 RS07640
gene id: 1912795:BK816_RS07640
uniprot id: A0A1D9MLD8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1912795:BK816 RS04530
gene id: 1912795:BK816_RS04530
uniprot id: A0A1D9MK41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1912795:BK816 RS05665
gene id: 1912795:BK816_RS05665
uniprot id: A0A1D9MKM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS00280
gene id: 1912795:BK816_RS00280
uniprot id: A0A1D9MIA3
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS03860
gene id: 1912795:BK816_RS03860
uniprot id: A0A1D9MJZ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1912795:BK816 RS03800
gene id: 1912795:BK816_RS03800
uniprot id: A0A1D9MJR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1912795:BK816 RS01845
gene id: 1912795:BK816_RS01845
uniprot id: A0A1D9MIM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1912795:BK816 RS01460
gene id: 1912795:BK816_RS01460
uniprot id: A0A1D9MIJ7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1912795:BK816 RS02200
gene id: 1912795:BK816_RS02200
uniprot id: A0A1D9MIZ7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1912795:BK816 RS07650
gene id: 1912795:BK816_RS07650
uniprot id: A0A1D9MLZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1912795:BK816 RS02170
gene id: 1912795:BK816_RS02170
uniprot id: A0A1D9MJ95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1912795:BK816 RS06405
gene id: 1912795:BK816_RS06405
uniprot id: A0A1D9ML03
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1912795:BK816 RS04540
gene id: 1912795:BK816_RS04540
uniprot id: A0A1D9MK23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1912795:BK816 RS07370
gene id: 1912795:BK816_RS07370
uniprot id: A0A1D9MLF6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1912795:BK816 RS04780
gene id: 1912795:BK816_RS04780
uniprot id: A0A1D9MKH4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

1912795:BK816 RS05720
gene id: 1912795:BK816_RS05720
uniprot id: A0A1D9ML08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1912795:BK816 RS05780
gene id: 1912795:BK816_RS05780
uniprot id: A0A1D9ML20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS02985
gene id: 1912795:BK816_RS02985
uniprot id: A0A1D9MJC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS00070
gene id: 1912795:BK816_RS00070
uniprot id: A0A1D9MI69
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS05230
gene id: 1912795:BK816_RS05230
uniprot id: A0A1D9MKL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1912795:BK816 RS04685
gene id: 1912795:BK816_RS04685
uniprot id: A0A1D9MMF3
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS07350
gene id: 1912795:BK816_RS07350
uniprot id: A0A1D9MLR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1912795:BK816 RS06370
gene id: 1912795:BK816_RS06370
uniprot id: A0A1D9MLC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1912795:BK816 RS05685
gene id: 1912795:BK816_RS05685
uniprot id: A0A1D9MKY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1912795:BK816 RS05330
gene id: 1912795:BK816_RS05330
uniprot id: A0A1D9MKH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1912795:BK816 RS04235
gene id: 1912795:BK816_RS04235
uniprot id: A0A1D9MKB0
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1912795:BK816 RS02300
gene id: 1912795:BK816_RS02300
uniprot id: A0A1D9MJ00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1912795:BK816 RS06960
gene id: 1912795:BK816_RS06960
uniprot id: A0A1D9MLK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1912795:BK816 RS07175
gene id: 1912795:BK816_RS07175
uniprot id: A0A1D9MLC3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1912795:BK816 RS06070
gene id: 1912795:BK816_RS06070
uniprot id: A0A1D9ML79
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS06590
gene id: 1912795:BK816_RS06590
uniprot id: A0A1D9ML32
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1912795:BK816 RS08550
gene id: 1912795:BK816_RS08550
uniprot id: A0A1D9MME9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS05875
gene id: 1912795:BK816_RS05875
uniprot id: A0A1D9MKN5
names: Similarity
messages: Belongs to the ribF family.

1912795:BK816 RS02180
gene id: 1912795:BK816_RS02180
uniprot id: A0A1D9MIZ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

1912795:BK816 RS05030
gene id: 1912795:BK816_RS05030
uniprot id: A0A1D9MKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1912795:BK816 RS05245
gene id: 1912795:BK816_RS05245
uniprot id: A0A1D9MK94
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1912795:BK816 RS08800
gene id: 1912795:BK816_RS08800
uniprot id: A0A1D9MMV2
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS03100
gene id: 1912795:BK816_RS03100
uniprot id: A0A1D9MJC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1912795:BK816 RS02010
gene id: 1912795:BK816_RS02010
uniprot id: A0A1D9MJ33
names: Similarity
messages: Belongs to the peptidase M1 family.

1912795:BK816 RS02005
gene id: 1912795:BK816_RS02005
uniprot id: A0A1D9MIT3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1912795:BK816 RS01860
gene id: 1912795:BK816_RS01860
uniprot id: A0A1D9MIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1912795:BK816 RS03060
gene id: 1912795:BK816_RS03060
uniprot id: A0A1D9MJL2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1912795:BK816 RS05855
gene id: 1912795:BK816_RS05855
uniprot id: A0A1D9MKR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1912795:BK816 RS05300
gene id: 1912795:BK816_RS05300
uniprot id: A0A1D9MKV2
names: Similarity
messages: Belongs to the thymidine kinase family.

1912795:BK816 RS02650
gene id: 1912795:BK816_RS02650
uniprot id: A0A1D9MJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1912795:BK816 RS03915
gene id: 1912795:BK816_RS03915
uniprot id: A0A1D9MK03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1912795:BK816 RS03210
gene id: 1912795:BK816_RS03210
uniprot id: A0A1D9MJ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS05450
gene id: 1912795:BK816_RS05450
uniprot id: A0A1D9MKQ2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1912795:BK816 RS04400
gene id: 1912795:BK816_RS04400
uniprot id: A0A1D9MKD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1912795:BK816 RS06805
gene id: 1912795:BK816_RS06805
uniprot id: A0A1D9MLJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1912795:BK816 RS00675
gene id: 1912795:BK816_RS00675
uniprot id: A0A1D9MIH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1912795:BK816 RS00500
gene id: 1912795:BK816_RS00500
uniprot id: A0A1D9MI29
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1912795:BK816 RS02940
gene id: 1912795:BK816_RS02940
uniprot id: A0A1D9MJM7
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1912795:BK816 RS03890
gene id: 1912795:BK816_RS03890
uniprot id: A0A1D9MJR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1912795:BK816 RS04800
gene id: 1912795:BK816_RS04800
uniprot id: A0A1D9MK82
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1912795:BK816 RS06125
gene id: 1912795:BK816_RS06125
uniprot id: A0A1D9MKN9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1912795:BK816 RS02090
gene id: 1912795:BK816_RS02090
uniprot id: A0A1D9MIW1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1912795:BK816 RS04580
gene id: 1912795:BK816_RS04580
uniprot id: A0A1D9MK50
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1912795:BK816 RS01740
gene id: 1912795:BK816_RS01740
uniprot id: A0A1D9MIP0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS05035
gene id: 1912795:BK816_RS05035
uniprot id: A0A1D9MKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1912795:BK816 RS04360
gene id: 1912795:BK816_RS04360
uniprot id: A0A1D9MJZ3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1912795:BK816 RS03230
gene id: 1912795:BK816_RS03230
uniprot id: A0A1D9MJF1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1912795:BK816 RS02475
gene id: 1912795:BK816_RS02475
uniprot id: A0A1D9MJ28
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1912795:BK816 RS05805
gene id: 1912795:BK816_RS05805
uniprot id: A0A1D9MKV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1912795:BK816 RS08995
gene id: 1912795:BK816_RS08995
uniprot id: A0A1D9MM57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1912795:BK816 RS07560
gene id: 1912795:BK816_RS07560
uniprot id: A0A1D9MLJ1
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS04160
gene id: 1912795:BK816_RS04160
uniprot id: A0A1D9MJV4
names: Similarity
messages: Belongs to the YciI family.

1912795:BK816 RS05865
gene id: 1912795:BK816_RS05865
uniprot id: A0A1D9MKR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1912795:BK816 RS02720
gene id: 1912795:BK816_RS02720
uniprot id: A0A1D9MJ66
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS03700
gene id: 1912795:BK816_RS03700
uniprot id: A0A1D9MJJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1912795:BK816 RS01530
gene id: 1912795:BK816_RS01530
uniprot id: A0A1D9MIV6
names: Similarity
messages: Belongs to the catalase family.

1912795:BK816 RS01850
gene id: 1912795:BK816_RS01850
uniprot id: A0A1D9MIS8
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS01445
gene id: 1912795:BK816_RS01445
uniprot id: A0A1D9MIL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1912795:BK816 RS07865
gene id: 1912795:BK816_RS07865
uniprot id: A0A1D9MLN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1912795:BK816 RS02655
gene id: 1912795:BK816_RS02655
uniprot id: A0A1D9MJ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1912795:BK816 RS04935
gene id: 1912795:BK816_RS04935
uniprot id: A0A1D9MKG8
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS01255
gene id: 1912795:BK816_RS01255
uniprot id: A0A1D9MIT1
names: Similarity
messages: Belongs to the peptidase S8 family.

1912795:BK816 RS06280
gene id: 1912795:BK816_RS06280
uniprot id: A0A1D9MKY8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1912795:BK816 RS07670
gene id: 1912795:BK816_RS07670
uniprot id: A0A1D9MLL0
names: Similarity
messages: Belongs to the peptidase S13 family.

1912795:BK816 RS02800
gene id: 1912795:BK816_RS02800
uniprot id: A0A1D9MJ98
names: Similarity
messages: Belongs to the arginine deiminase family.

1912795:BK816 RS06705
gene id: 1912795:BK816_RS06705
uniprot id: A0A1D9ML31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1912795:BK816 RS06180
gene id: 1912795:BK816_RS06180
uniprot id: A0A1D9ML62
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS07420
gene id: 1912795:BK816_RS07420
uniprot id: A0A1D9MLW9
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS02355
gene id: 1912795:BK816_RS02355
uniprot id: A0A1D9MJ01
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS07295
gene id: 1912795:BK816_RS07295
uniprot id: A0A1D9MKS7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1912795:BK816 RS04845
gene id: 1912795:BK816_RS04845
uniprot id: A0A1D9MK24
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1912795:BK816 RS04830
gene id: 1912795:BK816_RS04830
uniprot id: A0A1D9MKF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

1912795:BK816 RS01940
gene id: 1912795:BK816_RS01940
uniprot id: A0A1D9MIR6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1912795:BK816 RS03990
gene id: 1912795:BK816_RS03990
uniprot id: A0A1D9MK49
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1912795:BK816 RS02120
gene id: 1912795:BK816_RS02120
uniprot id: A0A1D9MJ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1912795:BK816 RS01965
gene id: 1912795:BK816_RS01965
uniprot id: A0A1D9MJ55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1912795:BK816 RS05385
gene id: 1912795:BK816_RS05385
uniprot id: A0A1D9MKI4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1912795:BK816 RS08910
gene id: 1912795:BK816_RS08910
uniprot id: A0A1D9MM47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1912795:BK816 RS05110
gene id: 1912795:BK816_RS05110
uniprot id: A0A1D9MKJ6
names: Similarity
messages: Belongs to the DapA family.

1912795:BK816 RS03655
gene id: 1912795:BK816_RS03655
uniprot id: A0A1D9MJN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1912795:BK816 RS06895
gene id: 1912795:BK816_RS06895
uniprot id: A0A1D9ML72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS00155
gene id: 1912795:BK816_RS00155
uniprot id: A0A1D9MHX2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1912795:BK816 RS05520
gene id: 1912795:BK816_RS05520
uniprot id: A0A1D9MKV6
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1912795:BK816 RS04345
gene id: 1912795:BK816_RS04345
uniprot id: A0A1D9MJU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1912795:BK816 RS01110
gene id: 1912795:BK816_RS01110
uniprot id: A0A1D9MIE1
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1912795:BK816 RS03150
gene id: 1912795:BK816_RS03150
uniprot id: A0A1D9MJ89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1912795:BK816 RS01835
gene id: 1912795:BK816_RS01835
uniprot id: A0A1D9MMP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1912795:BK816 RS03000
gene id: 1912795:BK816_RS03000
uniprot id: A0A1D9MJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1912795:BK816 RS07180
gene id: 1912795:BK816_RS07180
uniprot id: A0A1D9MLI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

1912795:BK816 RS05970
gene id: 1912795:BK816_RS05970
uniprot id: A0A1D9MKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1912795:BK816 RS05260
gene id: 1912795:BK816_RS05260
uniprot id: A0A1D9MKS2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS01265
gene id: 1912795:BK816_RS01265
uniprot id: A0A1D9MII6
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS04465
gene id: 1912795:BK816_RS04465
uniprot id: A0A1D9MK28
names: Similarity
messages: Belongs to the UPF0749 family.

1912795:BK816 RS01465
gene id: 1912795:BK816_RS01465
uniprot id: A0A1D9MIM2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1912795:BK816 RS03535
gene id: 1912795:BK816_RS03535
uniprot id: A0A1D9MJX9
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS06700
gene id: 1912795:BK816_RS06700
uniprot id: A0A1D9ML47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1912795:BK816 RS00275
gene id: 1912795:BK816_RS00275
uniprot id: A0A1D9MI92
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1912795:BK816 RS03625
gene id: 1912795:BK816_RS03625
uniprot id: A0A1D9MJN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1912795:BK816 RS02075
gene id: 1912795:BK816_RS02075
uniprot id: A0A1D9MIR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1912795:BK816 RS06035
gene id: 1912795:BK816_RS06035
uniprot id: A0A1D9MMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1912795:BK816 RS05320
gene id: 1912795:BK816_RS05320
uniprot id: A0A1D9MKF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS04355
gene id: 1912795:BK816_RS04355
uniprot id: A0A1D9MKB4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS03390
gene id: 1912795:BK816_RS03390
uniprot id: A0A1D9MJI3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1912795:BK816 RS03825
gene id: 1912795:BK816_RS03825
uniprot id: A0A1D9MJL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1912795:BK816 RS05215
gene id: 1912795:BK816_RS05215
uniprot id: A0A1D9MKE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1912795:BK816 RS01525
gene id: 1912795:BK816_RS01525
uniprot id: A0A1D9MIL0
names: Similarity
messages: Belongs to the Fur family.

1912795:BK816 RS04205
gene id: 1912795:BK816_RS04205
uniprot id: A0A1D9MJW5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1912795:BK816 RS01470
gene id: 1912795:BK816_RS01470
uniprot id: A0A1D9MIK3
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS03660
gene id: 1912795:BK816_RS03660
uniprot id: A0A1D9MJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1912795:BK816 RS07470
gene id: 1912795:BK816_RS07470
uniprot id: A0A1D9MLY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1912795:BK816 RS01885
gene id: 1912795:BK816_RS01885
uniprot id: A0A1D9MJ13
names: Similarity
messages: Belongs to the UPF0234 family.

1912795:BK816 RS07880
gene id: 1912795:BK816_RS07880
uniprot id: A0A1D9MMM3
names: Similarity
messages: Belongs to the HSP15 family.

1912795:BK816 RS03665
gene id: 1912795:BK816_RS03665
uniprot id: A0A1D9MJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1912795:BK816 RS01375
gene id: 1912795:BK816_RS01375
uniprot id: A0A1D9MMN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1912795:BK816 RS01870
gene id: 1912795:BK816_RS01870
uniprot id: A0A1D9MIQ6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1912795:BK816 RS03125
gene id: 1912795:BK816_RS03125
uniprot id: A0A1D9MJM2
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1912795:BK816 RS01705
gene id: 1912795:BK816_RS01705
uniprot id: A0A1D9MJ09
names: Similarity
messages: Belongs to the GST superfamily.

1912795:BK816 RS02060
gene id: 1912795:BK816_RS02060
uniprot id: A0A1D9MJ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1912795:BK816 RS03005
gene id: 1912795:BK816_RS03005
uniprot id: A0A1D9MJN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1912795:BK816 RS05020
gene id: 1912795:BK816_RS05020
uniprot id: A0A1D9MKN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1912795:BK816 RS00515
gene id: 1912795:BK816_RS00515
uniprot id: A0A1D9MID9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1912795:BK816 RS04340
gene id: 1912795:BK816_RS04340
uniprot id: A0A1D9MKC8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1912795:BK816 RS06600
gene id: 1912795:BK816_RS06600
uniprot id: A0A1D9ML81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1912795:BK816 RS05505
gene id: 1912795:BK816_RS05505
uniprot id: A0A1D9MKR2
names: Similarity
messages: Belongs to the TlyA family.

1912795:BK816 RS06555
gene id: 1912795:BK816_RS06555
uniprot id: A0A1D9MLC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1912795:BK816 RS05525
gene id: 1912795:BK816_RS05525
uniprot id: A0A1D9ML01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1912795:BK816 RS00140
gene id: 1912795:BK816_RS00140
uniprot id: A0A1D9MHV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1912795:BK816 RS06855
gene id: 1912795:BK816_RS06855
uniprot id: A0A1D9MLK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1912795:BK816 RS04670
gene id: 1912795:BK816_RS04670
uniprot id: A0A1D9MM75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1912795:BK816 RS05100
gene id: 1912795:BK816_RS05100
uniprot id: A0A1D9MKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS05615
gene id: 1912795:BK816_RS05615
uniprot id: A0A1D9MKJ9
names: Subcellular Location Annotation
messages: Cytoplasm

1912795:BK816 RS00150
gene id: 1912795:BK816_RS00150
uniprot id: A0A1D9MI55
names: Subcellular Location Annotation
messages: Membrane

1912795:BK816 RS05645
gene id: 1912795:BK816_RS05645
uniprot id: A0A1D9MKN8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1912795:BK816 RS03180
gene id: 1912795:BK816_RS03180
uniprot id: A0A1D9MMD4
names: Similarity
messages: Belongs to the peptidase M18 family.

1912795:BK816 RS03610
gene id: 1912795:BK816_RS03610
uniprot id: A0A1D9MJY2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS04045
gene id: 1912795:BK816_RS04045
uniprot id: A0A1D9MK59
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1912795:BK816 RS02250
gene id: 1912795:BK816_RS02250
uniprot id: A0A1D9MIY1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1912795:BK816 RS06520
gene id: 1912795:BK816_RS06520
uniprot id: A0A1D9MKZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1912795:BK816 RS03350
gene id: 1912795:BK816_RS03350
uniprot id: A0A1D9MJI7
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

1912795:BK816 RS02220
gene id: 1912795:BK816_RS02220
uniprot id: A0A1D9MJA0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1912795:BK816 RS02125
gene id: 1912795:BK816_RS02125
uniprot id: A0A1D9MIS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1912795:BK816 RS05095
gene id: 1912795:BK816_RS05095
uniprot id: A0A1D9MKC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1912795:BK816 RS06300
gene id: 1912795:BK816_RS06300
uniprot id: A0A1D9ML29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS06530
gene id: 1912795:BK816_RS06530
uniprot id: A0A1D9ML35
names: Similarity
messages: Belongs to the LOG family.

1912795:BK816 RS06150
gene id: 1912795:BK816_RS06150
uniprot id: A0A1D9MKW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1912795:BK816 RS05070
gene id: 1912795:BK816_RS05070
uniprot id: A0A1D9MKQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1912795:BK816 RS01840
gene id: 1912795:BK816_RS01840
uniprot id: A0A1D9MJ32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1912795:BK816 RS04370
gene id: 1912795:BK816_RS04370
uniprot id: A0A1D9MK19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1912795:BK816 RS06570
gene id: 1912795:BK816_RS06570
uniprot id: A0A1D9ML25
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1912795:BK816 RS08890
gene id: 1912795:BK816_RS08890
uniprot id: A0A1D9MMI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1912795:BK816 RS00195
gene id: 1912795:BK816_RS00195
uniprot id: A0A1D9MHX7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1912795:BK816 RS06200
gene id: 1912795:BK816_RS06200
uniprot id: A0A1D9ML84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1912795:BK816 RS07845
gene id: 1912795:BK816_RS07845
uniprot id: A0A1D9MLN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane