1904616:BFF78 RS17325
gene id: 1904616:BFF78_RS17325
uniprot id: A0A1D7YNJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS33990
gene id: 1904616:BFF78_RS33990
uniprot id: A0A1D7YIN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1904616:BFF78 RS07330
gene id: 1904616:BFF78_RS07330
uniprot id: A0A1D7Y5U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1904616:BFF78 RS35505
gene id: 1904616:BFF78_RS35505
uniprot id: A0A1D7YPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1904616:BFF78 RS05030
gene id: 1904616:BFF78_RS05030
uniprot id: A0A1D7Y4Z1
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1904616:BFF78 RS22040
gene id: 1904616:BFF78_RS22040
uniprot id: A0A1D7YCP5
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1904616:BFF78 RS24690
gene id: 1904616:BFF78_RS24690
uniprot id: A0A1D7YDX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1904616:BFF78 RS18615
gene id: 1904616:BFF78_RS18615
uniprot id: A0A1D7YBG3
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS28040
gene id: 1904616:BFF78_RS28040
uniprot id: A0A1D7YFI7
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1904616:BFF78 RS41000
gene id: 1904616:BFF78_RS41000
uniprot id: A0A1D7YLY6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS13000
gene id: 1904616:BFF78_RS13000
uniprot id: A0A1D7Y8M3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS30965
gene id: 1904616:BFF78_RS30965
uniprot id: A0A1D7YPB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1904616:BFF78 RS08905
gene id: 1904616:BFF78_RS08905
uniprot id: A0A1D7Y708
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

1904616:BFF78 RS12355
gene id: 1904616:BFF78_RS12355
uniprot id: A0A1D7Y8S0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1904616:BFF78 RS33325
gene id: 1904616:BFF78_RS33325
uniprot id: A0A1D7YIF0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS16830
gene id: 1904616:BFF78_RS16830
uniprot id: A0A1D7YA45
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1904616:BFF78 RS35910
gene id: 1904616:BFF78_RS35910
uniprot id: A0A1D7Y354
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1904616:BFF78 RS13045
gene id: 1904616:BFF78_RS13045
uniprot id: A0A1D7Y8B5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1904616:BFF78 RS34165
gene id: 1904616:BFF78_RS34165
uniprot id: A0A1D7YIL7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS40325
gene id: 1904616:BFF78_RS40325
uniprot id: A0A1D7YLU7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS13240
gene id: 1904616:BFF78_RS13240
uniprot id: A0A1D7Y8U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1904616:BFF78 RS17105
gene id: 1904616:BFF78_RS17105
uniprot id: A0A1D7YAG8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS09820
gene id: 1904616:BFF78_RS09820
uniprot id: A0A1D7Y6S8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1904616:BFF78 RS04035
gene id: 1904616:BFF78_RS04035
uniprot id: A0A1D7Y421
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS25500
gene id: 1904616:BFF78_RS25500
uniprot id: A0A1D7YEB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1904616:BFF78 RS06215
gene id: 1904616:BFF78_RS06215
uniprot id: A0A1D7Y580
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS23880
gene id: 1904616:BFF78_RS23880
uniprot id: A0A1D7YED1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS13940
gene id: 1904616:BFF78_RS13940
uniprot id: A0A1D7Y9I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1904616:BFF78 RS17435
gene id: 1904616:BFF78_RS17435
uniprot id: A0A1D7YNP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1904616:BFF78 RS24940
gene id: 1904616:BFF78_RS24940
uniprot id: A0A1D7YEU6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1904616:BFF78 RS11400
gene id: 1904616:BFF78_RS11400
uniprot id: A0A1D7YN95
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1904616:BFF78 RS06795
gene id: 1904616:BFF78_RS06795
uniprot id: A0A1D7Y5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS10095
gene id: 1904616:BFF78_RS10095
uniprot id: A0A1D7Y7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1904616:BFF78 RS44730
gene id: 1904616:BFF78_RS44730
uniprot id: A0A1D7Y8X9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1904616:BFF78 RS11000
gene id: 1904616:BFF78_RS11000
uniprot id: A0A1D7Y7G1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1904616:BFF78 RS39000
gene id: 1904616:BFF78_RS39000
uniprot id: A0A1D7YL64
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1904616:BFF78 RS06480
gene id: 1904616:BFF78_RS06480
uniprot id: A0A1D7Y575
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1904616:BFF78 RS04825
gene id: 1904616:BFF78_RS04825
uniprot id: A0A1D7Y4D5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS33340
gene id: 1904616:BFF78_RS33340
uniprot id: A0A1D7YI85
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1904616:BFF78 RS07305
gene id: 1904616:BFF78_RS07305
uniprot id: A0A1D7Y5T4
names: Similarity
messages: Belongs to the CdaR family.

1904616:BFF78 RS16030
gene id: 1904616:BFF78_RS16030
uniprot id: A0A1D7Y9S0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34190
gene id: 1904616:BFF78_RS34190
uniprot id: A0A1D7YIV1
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1904616:BFF78 RS40695
gene id: 1904616:BFF78_RS40695
uniprot id: A0A1D7YLZ8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1904616:BFF78 RS32085
gene id: 1904616:BFF78_RS32085
uniprot id: A0A1D7YHR0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1904616:BFF78 RS20380
gene id: 1904616:BFF78_RS20380
uniprot id: A0A1D7YBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.
messages: Secreted

1904616:BFF78 RS17145
gene id: 1904616:BFF78_RS17145
uniprot id: A0A1D7YA97
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1904616:BFF78 RS33565
gene id: 1904616:BFF78_RS33565
uniprot id: A0A1D7YIG5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1904616:BFF78 RS02290
gene id: 1904616:BFF78_RS02290
uniprot id: A0A1D7Y3D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1904616:BFF78 RS00450
gene id: 1904616:BFF78_RS00450
uniprot id: A0A1D7Y2F5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS33775
gene id: 1904616:BFF78_RS33775
uniprot id: A0A1D7YIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS18085
gene id: 1904616:BFF78_RS18085
uniprot id: A0A1D7YBK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1904616:BFF78 RS19570
gene id: 1904616:BFF78_RS19570
uniprot id: A0A1D7YBX6
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1904616:BFF78 RS05165
gene id: 1904616:BFF78_RS05165
uniprot id: A0A1D7Y4K4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS26460
gene id: 1904616:BFF78_RS26460
uniprot id: A0A1D7YEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS31810
gene id: 1904616:BFF78_RS31810
uniprot id: A0A1D7YHL0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS39570
gene id: 1904616:BFF78_RS39570
uniprot id: A0A1D7YLU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS34075
gene id: 1904616:BFF78_RS34075
uniprot id: A0A1D7YIR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1904616:BFF78 RS18370
gene id: 1904616:BFF78_RS18370
uniprot id: A0A1D7YBQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS24550
gene id: 1904616:BFF78_RS24550
uniprot id: A0A1D7YE40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1904616:BFF78 RS25300
gene id: 1904616:BFF78_RS25300
uniprot id: A0A1D7YF09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS15640
gene id: 1904616:BFF78_RS15640
uniprot id: A0A1D7Y9J9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS30580
gene id: 1904616:BFF78_RS30580
uniprot id: A0A1D7YH03
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1904616:BFF78 RS33635
gene id: 1904616:BFF78_RS33635
uniprot id: A0A1D7YIC7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1904616:BFF78 RS05385
gene id: 1904616:BFF78_RS05385
uniprot id: A0A1D7Y5D8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1904616:BFF78 RS32090
gene id: 1904616:BFF78_RS32090
uniprot id: A0A1D7YHT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1904616:BFF78 RS05090
gene id: 1904616:BFF78_RS05090
uniprot id: A0A1D7Y4I2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1904616:BFF78 RS07185
gene id: 1904616:BFF78_RS07185
uniprot id: A0A1D7Y5S5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS32325
gene id: 1904616:BFF78_RS32325
uniprot id: A0A1D7YHQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1904616:BFF78 RS12155
gene id: 1904616:BFF78_RS12155
uniprot id: A0A1D7Y7W8
names: Similarity
messages: Belongs to the peptidase M1 family.

1904616:BFF78 RS17840
gene id: 1904616:BFF78_RS17840
uniprot id: A0A1D7YB23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS38915
gene id: 1904616:BFF78_RS38915
uniprot id: A0A1D7YKX0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS25335
gene id: 1904616:BFF78_RS25335
uniprot id: A0A1D7YEK0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1904616:BFF78 RS27800
gene id: 1904616:BFF78_RS27800
uniprot id: A0A1D7YFE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1904616:BFF78 RS18930
gene id: 1904616:BFF78_RS18930
uniprot id: A0A1D7YBC8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS26655
gene id: 1904616:BFF78_RS26655
uniprot id: A0A1D7YF64
names: Similarity
messages: Belongs to the TPP enzyme family.

1904616:BFF78 RS20780
gene id: 1904616:BFF78_RS20780
uniprot id: A0A1D7YC37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1904616:BFF78 RS17360
gene id: 1904616:BFF78_RS17360
uniprot id: A0A1D7YAR4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1904616:BFF78 RS29745
gene id: 1904616:BFF78_RS29745
uniprot id: A0A1D7YGC6
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1904616:BFF78 RS28685
gene id: 1904616:BFF78_RS28685
uniprot id: A0A1D7YGM5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1904616:BFF78 RS32200
gene id: 1904616:BFF78_RS32200
uniprot id: A0A1D7YHU9
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1904616:BFF78 RS12615
gene id: 1904616:BFF78_RS12615
uniprot id: A0A1D7Y821
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1904616:BFF78 RS31170
gene id: 1904616:BFF78_RS31170
uniprot id: A0A1D7YHC6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1904616:BFF78 RS07730
gene id: 1904616:BFF78_RS07730
uniprot id: A0A1D7Y5V3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS16280
gene id: 1904616:BFF78_RS16280
uniprot id: A0A1D7YNE0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1904616:BFF78 RS05235
gene id: 1904616:BFF78_RS05235
uniprot id: A0A1D7YN09
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1904616:BFF78 RS05915
gene id: 1904616:BFF78_RS05915
uniprot id: A0A1D7Y534
names: Similarity
messages: Belongs to the DapA family.

1904616:BFF78 RS30400
gene id: 1904616:BFF78_RS30400
uniprot id: A0A1D7YGY2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Belongs to the sulfur carrier protein TusA family.

1904616:BFF78 RS03075
gene id: 1904616:BFF78_RS03075
uniprot id: A0A1D7Y404
names: Similarity
messages: Belongs to the TPP enzyme family.

1904616:BFF78 RS30795
gene id: 1904616:BFF78_RS30795
uniprot id: A0A1D7YHP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1904616:BFF78 RS32415
gene id: 1904616:BFF78_RS32415
uniprot id: A0A1D7YHX6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS04720
gene id: 1904616:BFF78_RS04720
uniprot id: A0A1D7Y4D4
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1904616:BFF78 RS16230
gene id: 1904616:BFF78_RS16230
uniprot id: A0A1D7YAB4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1904616:BFF78 RS10210
gene id: 1904616:BFF78_RS10210
uniprot id: A0A1D7Y6V5
names: Similarity
messages: Belongs to the catalase family.

1904616:BFF78 RS23670
gene id: 1904616:BFF78_RS23670
uniprot id: A0A1D7YDH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS10725
gene id: 1904616:BFF78_RS10725
uniprot id: A0A1D7Y7H9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS12550
gene id: 1904616:BFF78_RS12550
uniprot id: A0A1D7Y8V4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1904616:BFF78 RS22660
gene id: 1904616:BFF78_RS22660
uniprot id: A0A1D7YCY3
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1904616:BFF78 RS18020
gene id: 1904616:BFF78_RS18020
uniprot id: A0A1D7YAQ6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24540
gene id: 1904616:BFF78_RS24540
uniprot id: A0A1D7YE23
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1904616:BFF78 RS33025
gene id: 1904616:BFF78_RS33025
uniprot id: A0A1D7YI78
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS20390
gene id: 1904616:BFF78_RS20390
uniprot id: A0A1D7YCN1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS12175
gene id: 1904616:BFF78_RS12175
uniprot id: A0A1D7Y875
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1904616:BFF78 RS04010
gene id: 1904616:BFF78_RS04010
uniprot id: A0A1D7Y4P4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1904616:BFF78 RS01725
gene id: 1904616:BFF78_RS01725
uniprot id: A0A1D7Y3E5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS20820
gene id: 1904616:BFF78_RS20820
uniprot id: A0A1D7YC85
names: Similarity
messages: Belongs to the peptidase M18 family.

1904616:BFF78 RS25930
gene id: 1904616:BFF78_RS25930
uniprot id: A0A1D7YEQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1904616:BFF78 RS36465
gene id: 1904616:BFF78_RS36465
uniprot id: A0A1D7YJR2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS18745
gene id: 1904616:BFF78_RS18745
uniprot id: A0A1D7YB28
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1904616:BFF78 RS42025
gene id: 1904616:BFF78_RS42025
uniprot id: A0A1D7YMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the N-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1904616:BFF78 RS21040
gene id: 1904616:BFF78_RS21040
uniprot id: A0A1D7YCE4
names: Similarity
messages: Belongs to the FPG family.

1904616:BFF78 RS30810
gene id: 1904616:BFF78_RS30810
uniprot id: A0A1D7YH63
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1904616:BFF78 RS37530
gene id: 1904616:BFF78_RS37530
uniprot id: A0A1D7YK73
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS14215
gene id: 1904616:BFF78_RS14215
uniprot id: A0A1D7Y8V1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1904616:BFF78 RS36225
gene id: 1904616:BFF78_RS36225
uniprot id: A0A1D7YJS3
names: Similarity
messages: Belongs to the asparaginase 1 family.

1904616:BFF78 RS27145
gene id: 1904616:BFF78_RS27145
uniprot id: A0A1D7YFF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1904616:BFF78 RS38000
gene id: 1904616:BFF78_RS38000
uniprot id: A0A1D7YKF0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1904616:BFF78 RS00460
gene id: 1904616:BFF78_RS00460
uniprot id: A0A1D7YMP2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS06425
gene id: 1904616:BFF78_RS06425
uniprot id: A0A1D7Y566
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1904616:BFF78 RS28885
gene id: 1904616:BFF78_RS28885
uniprot id: A0A1D7YGQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS21915
gene id: 1904616:BFF78_RS21915
uniprot id: A0A1D7YNV8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24180
gene id: 1904616:BFF78_RS24180
uniprot id: A0A1D7YE12
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1904616:BFF78 RS33795
gene id: 1904616:BFF78_RS33795
uniprot id: A0A1D7YIK4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1904616:BFF78 RS10975
gene id: 1904616:BFF78_RS10975
uniprot id: A0A1D7Y7A2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS11050
gene id: 1904616:BFF78_RS11050
uniprot id: A0A1D7Y7R5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS10980
gene id: 1904616:BFF78_RS10980
uniprot id: A0A1D7Y817
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS20550
gene id: 1904616:BFF78_RS20550
uniprot id: A0A1D7YC80
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS09450
gene id: 1904616:BFF78_RS09450
uniprot id: A0A1D7Y6N5
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1904616:BFF78 RS34755
gene id: 1904616:BFF78_RS34755
uniprot id: A0A1D7YJM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1904616:BFF78 RS18700
gene id: 1904616:BFF78_RS18700
uniprot id: A0A1D7YBD9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1904616:BFF78 RS34375
gene id: 1904616:BFF78_RS34375
uniprot id: A0A1D7YIQ3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24435
gene id: 1904616:BFF78_RS24435
uniprot id: A0A1D7YDT8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1904616:BFF78 RS37015
gene id: 1904616:BFF78_RS37015
uniprot id: A0A1D7YK43
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS38965
gene id: 1904616:BFF78_RS38965
uniprot id: A0A1D7YKX9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1904616:BFF78 RS14320
gene id: 1904616:BFF78_RS14320
uniprot id: A0A1D7Y9Q9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1904616:BFF78 RS14210
gene id: 1904616:BFF78_RS14210
uniprot id: A0A1D7Y8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS02585
gene id: 1904616:BFF78_RS02585
uniprot id: A0A1D7Y3G7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1904616:BFF78 RS36765
gene id: 1904616:BFF78_RS36765
uniprot id: A0A1D7YKK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1904616:BFF78 RS38595
gene id: 1904616:BFF78_RS38595
uniprot id: A0A1D7YKQ4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1904616:BFF78 RS22680
gene id: 1904616:BFF78_RS22680
uniprot id: A0A1D7YD64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1904616:BFF78 RS17765
gene id: 1904616:BFF78_RS17765
uniprot id: A0A1D7YAK5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS35970
gene id: 1904616:BFF78_RS35970
uniprot id: A0A1D7YJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS31995
gene id: 1904616:BFF78_RS31995
uniprot id: A0A1D7YHJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS28035
gene id: 1904616:BFF78_RS28035
uniprot id: A0A1D7YPM7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1904616:BFF78 RS09910
gene id: 1904616:BFF78_RS09910
uniprot id: A0A1D7Y7H8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS01620
gene id: 1904616:BFF78_RS01620
uniprot id: A0A1D7YMM6
names: Similarity
messages: Belongs to the universal stress protein A family.

1904616:BFF78 RS09845
gene id: 1904616:BFF78_RS09845
uniprot id: A0A1D7Y6Q7
names: Similarity
messages: Belongs to the fabD family.

1904616:BFF78 RS35555
gene id: 1904616:BFF78_RS35555
uniprot id: A0A1D7YJA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS40610
gene id: 1904616:BFF78_RS40610
uniprot id: A0A1D7YLQ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS08910
gene id: 1904616:BFF78_RS08910
uniprot id: A0A1D7Y6R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

1904616:BFF78 RS25650
gene id: 1904616:BFF78_RS25650
uniprot id: A0A1D7YEK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS03235
gene id: 1904616:BFF78_RS03235
uniprot id: A0A1D7Y3P9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1904616:BFF78 RS31045
gene id: 1904616:BFF78_RS31045
uniprot id: A0A1D7YH80
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS39730
gene id: 1904616:BFF78_RS39730
uniprot id: A0A1D7YLX2
names: Similarity
messages: Belongs to the fructosamine kinase family.

1904616:BFF78 RS35560
gene id: 1904616:BFF78_RS35560
uniprot id: A0A1D7YJG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1904616:BFF78 RS26690
gene id: 1904616:BFF78_RS26690
uniprot id: A0A1D7YFQ5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS40050
gene id: 1904616:BFF78_RS40050
uniprot id: A0A1D7YLM0
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1904616:BFF78 RS25985
gene id: 1904616:BFF78_RS25985
uniprot id: A0A1D7YEK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1904616:BFF78 RS19800
gene id: 1904616:BFF78_RS19800
uniprot id: A0A1D7YBX9
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS35460
gene id: 1904616:BFF78_RS35460
uniprot id: A0A1D7YJE9
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS15510
gene id: 1904616:BFF78_RS15510
uniprot id: A0A1D7Y9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS30790
gene id: 1904616:BFF78_RS30790
uniprot id: A0A1D7YGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1904616:BFF78 RS33680
gene id: 1904616:BFF78_RS33680
uniprot id: A0A1D7YID5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS16775
gene id: 1904616:BFF78_RS16775
uniprot id: A0A1D7YAY7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS38215
gene id: 1904616:BFF78_RS38215
uniprot id: A0A1D7YKN6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1904616:BFF78 RS13220
gene id: 1904616:BFF78_RS13220
uniprot id: A0A1D7Y8R1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1904616:BFF78 RS40380
gene id: 1904616:BFF78_RS40380
uniprot id: A0A1D7YLQ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS11165
gene id: 1904616:BFF78_RS11165
uniprot id: A0A1D7Y7C8
names: Similarity
messages: Belongs to the thioesterase family.

1904616:BFF78 RS35570
gene id: 1904616:BFF78_RS35570
uniprot id: A0A1D7YJB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1904616:BFF78 RS32385
gene id: 1904616:BFF78_RS32385
uniprot id: A0A1D7YHV3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS17820
gene id: 1904616:BFF78_RS17820
uniprot id: A0A1D7YAT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS26575
gene id: 1904616:BFF78_RS26575
uniprot id: A0A1D7YFM9
names: Similarity
messages: Belongs to the group II decarboxylase family.

1904616:BFF78 RS20275
gene id: 1904616:BFF78_RS20275
uniprot id: A0A1D7YCK6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS36415
gene id: 1904616:BFF78_RS36415
uniprot id: A0A1D7YJU9
names: Similarity
messages: Belongs to the CutA family.

1904616:BFF78 RS48100
gene id: 1904616:BFF78_RS48100
uniprot id: A0A1D7Y6M1
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1904616:BFF78 RS25250
gene id: 1904616:BFF78_RS25250
uniprot id: A0A1D7YEE9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1904616:BFF78 RS09335
gene id: 1904616:BFF78_RS09335
uniprot id: A0A1D7YN15
names: Similarity
messages: Belongs to the asp23 family.

1904616:BFF78 RS34100
gene id: 1904616:BFF78_RS34100
uniprot id: A0A1D7YIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1904616:BFF78 RS04020
gene id: 1904616:BFF78_RS04020
uniprot id: A0A1D7Y419
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS33975
gene id: 1904616:BFF78_RS33975
uniprot id: A0A1D7YII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1904616:BFF78 RS31380
gene id: 1904616:BFF78_RS31380
uniprot id: A0A1D7YHF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1904616:BFF78 RS23100
gene id: 1904616:BFF78_RS23100
uniprot id: A0A1D7YD62
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1904616:BFF78 RS32280
gene id: 1904616:BFF78_RS32280
uniprot id: A0A1D7YHM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS38025
gene id: 1904616:BFF78_RS38025
uniprot id: A0A1D7YKN3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS21515
gene id: 1904616:BFF78_RS21515
uniprot id: A0A1D7YCF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1904616:BFF78 RS11535
gene id: 1904616:BFF78_RS11535
uniprot id: A0A1D7Y7W7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS06990
gene id: 1904616:BFF78_RS06990
uniprot id: A0A1D7Y5G7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS10845
gene id: 1904616:BFF78_RS10845
uniprot id: A0A1D7Y7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1904616:BFF78 RS23925
gene id: 1904616:BFF78_RS23925
uniprot id: A0A1D7YDW9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34010
gene id: 1904616:BFF78_RS34010
uniprot id: A0A1D7YIP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS13440
gene id: 1904616:BFF78_RS13440
uniprot id: A0A1D7YNB8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41250
gene id: 1904616:BFF78_RS41250
uniprot id: A0A1D7YM59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1904616:BFF78 RS02860
gene id: 1904616:BFF78_RS02860
uniprot id: A0A1D7Y3I7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1904616:BFF78 RS30925
gene id: 1904616:BFF78_RS30925
uniprot id: A0A1D7YH58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

1904616:BFF78 RS28160
gene id: 1904616:BFF78_RS28160
uniprot id: A0A1D7YFL4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1904616:BFF78 RS14780
gene id: 1904616:BFF78_RS14780
uniprot id: A0A1D7Y960
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1904616:BFF78 RS14890
gene id: 1904616:BFF78_RS14890
uniprot id: A0A1D7YA21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1904616:BFF78 RS29180
gene id: 1904616:BFF78_RS29180
uniprot id: A0A1D7YGE6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1904616:BFF78 RS38200
gene id: 1904616:BFF78_RS38200
uniprot id: A0A1D7YKI2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1904616:BFF78 RS02430
gene id: 1904616:BFF78_RS02430
uniprot id: A0A1D7Y3C3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS30775
gene id: 1904616:BFF78_RS30775
uniprot id: A0A1D7YGX3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1904616:BFF78 RS33735
gene id: 1904616:BFF78_RS33735
uniprot id: A0A1D7YIK5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS15260
gene id: 1904616:BFF78_RS15260
uniprot id: A0A1D7Y9K6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS04975
gene id: 1904616:BFF78_RS04975
uniprot id: A0A1D7Y4Y2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS16050
gene id: 1904616:BFF78_RS16050
uniprot id: A0A1D7YAL5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS35745
gene id: 1904616:BFF78_RS35745
uniprot id: A0A1D7YK46
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS31610
gene id: 1904616:BFF78_RS31610
uniprot id: A0A1D7YHH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS29345
gene id: 1904616:BFF78_RS29345
uniprot id: A0A1D7YG59
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS02240
gene id: 1904616:BFF78_RS02240
uniprot id: A0A1D7YMT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS32515
gene id: 1904616:BFF78_RS32515
uniprot id: A0A1D7YHT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS13850
gene id: 1904616:BFF78_RS13850
uniprot id: A0A1D7Y8P2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1904616:BFF78 RS03255
gene id: 1904616:BFF78_RS03255
uniprot id: A0A1D7Y3Q1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34240
gene id: 1904616:BFF78_RS34240
uniprot id: A0A1D7YIT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1904616:BFF78 RS08880
gene id: 1904616:BFF78_RS08880
uniprot id: A0A1D7Y6I4
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

1904616:BFF78 RS31745
gene id: 1904616:BFF78_RS31745
uniprot id: A0A1D7YHD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1904616:BFF78 RS28840
gene id: 1904616:BFF78_RS28840
uniprot id: A0A1D7YG61
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS15810
gene id: 1904616:BFF78_RS15810
uniprot id: A0A1D7YA43
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1904616:BFF78 RS01590
gene id: 1904616:BFF78_RS01590
uniprot id: A0A1D7Y314
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS21595
gene id: 1904616:BFF78_RS21595
uniprot id: A0A1D7YCP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1904616:BFF78 RS28145
gene id: 1904616:BFF78_RS28145
uniprot id: A0A1D7YFW7
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1904616:BFF78 RS12035
gene id: 1904616:BFF78_RS12035
uniprot id: A0A1D7Y7U8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS30050
gene id: 1904616:BFF78_RS30050
uniprot id: A0A1D7YGH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1904616:BFF78 RS14195
gene id: 1904616:BFF78_RS14195
uniprot id: A0A1D7Y978
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1904616:BFF78 RS16595
gene id: 1904616:BFF78_RS16595
uniprot id: A0A1D7YAV8
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

1904616:BFF78 RS35580
gene id: 1904616:BFF78_RS35580
uniprot id: A0A1D7YJH0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS26625
gene id: 1904616:BFF78_RS26625
uniprot id: A0A1D7YEV4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1904616:BFF78 RS21240
gene id: 1904616:BFF78_RS21240
uniprot id: A0A1D7YCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1904616:BFF78 RS15945
gene id: 1904616:BFF78_RS15945
uniprot id: A0A1D7Y9Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1904616:BFF78 RS14735
gene id: 1904616:BFF78_RS14735
uniprot id: A0A1D7Y9K0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1904616:BFF78 RS30215
gene id: 1904616:BFF78_RS30215
uniprot id: A0A1D7YGK7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS21585
gene id: 1904616:BFF78_RS21585
uniprot id: A0A1D7YCX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1904616:BFF78 RS29855
gene id: 1904616:BFF78_RS29855
uniprot id: A0A1D7YGP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1904616:BFF78 RS25685
gene id: 1904616:BFF78_RS25685
uniprot id: A0A1D7YEE3
names: Similarity
messages: Belongs to the AHA1 family.

1904616:BFF78 RS20330
gene id: 1904616:BFF78_RS20330
uniprot id: A0A1D7YC98
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS23745
gene id: 1904616:BFF78_RS23745
uniprot id: A0A1D7YNU4
names: Similarity
messages: Belongs to the citrate synthase family.

1904616:BFF78 RS19545
gene id: 1904616:BFF78_RS19545
uniprot id: A0A1D7YBH1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS15940
gene id: 1904616:BFF78_RS15940
uniprot id: A0A1D7Y9X8
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1904616:BFF78 RS30875
gene id: 1904616:BFF78_RS30875
uniprot id: A0A1D7YPB2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS11070
gene id: 1904616:BFF78_RS11070
uniprot id: A0A1D7Y7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS29805
gene id: 1904616:BFF78_RS29805
uniprot id: A0A1D7YGM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS17610
gene id: 1904616:BFF78_RS17610
uniprot id: A0A1D7YAZ2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1904616:BFF78 RS29810
gene id: 1904616:BFF78_RS29810
uniprot id: A0A1D7YGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS06485
gene id: 1904616:BFF78_RS06485
uniprot id: A0A1D7Y578
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34270
gene id: 1904616:BFF78_RS34270
uniprot id: A0A1D7YIU4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS19185
gene id: 1904616:BFF78_RS19185
uniprot id: A0A1D7YBA3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS40775
gene id: 1904616:BFF78_RS40775
uniprot id: A0A1D7YLT3
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS01900
gene id: 1904616:BFF78_RS01900
uniprot id: A0A1D7Y3H2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS24410
gene id: 1904616:BFF78_RS24410
uniprot id: A0A1D7YE03
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS12165
gene id: 1904616:BFF78_RS12165
uniprot id: A0A1D7Y874
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS28180
gene id: 1904616:BFF78_RS28180
uniprot id: A0A1D7YPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1904616:BFF78 RS20460
gene id: 1904616:BFF78_RS20460
uniprot id: A0A1D7YC18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1904616:BFF78 RS28540
gene id: 1904616:BFF78_RS28540
uniprot id: A0A1D7YG35
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1904616:BFF78 RS32610
gene id: 1904616:BFF78_RS32610
uniprot id: A0A1D7YHV6
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1904616:BFF78 RS21105
gene id: 1904616:BFF78_RS21105
uniprot id: A0A1D7YCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1904616:BFF78 RS23405
gene id: 1904616:BFF78_RS23405
uniprot id: A0A1D7YDJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1904616:BFF78 RS27735
gene id: 1904616:BFF78_RS27735
uniprot id: A0A1D7YFE8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS35920
gene id: 1904616:BFF78_RS35920
uniprot id: A0A1D7YK77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1904616:BFF78 RS18665
gene id: 1904616:BFF78_RS18665
uniprot id: A0A1D7YB12
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS40805
gene id: 1904616:BFF78_RS40805
uniprot id: A0A1D7YM22
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS21205
gene id: 1904616:BFF78_RS21205
uniprot id: A0A1D7YCA0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1904616:BFF78 RS13525
gene id: 1904616:BFF78_RS13525
uniprot id: A0A1D7Y8V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1904616:BFF78 RS27125
gene id: 1904616:BFF78_RS27125
uniprot id: A0A1D7YFE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1904616:BFF78 RS03475
gene id: 1904616:BFF78_RS03475
uniprot id: A0A1D7Y3T7
names: Similarity
messages: Belongs to the peptidase S1 family.

1904616:BFF78 RS31545
gene id: 1904616:BFF78_RS31545
uniprot id: A0A1D7YHF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1904616:BFF78 RS03365
gene id: 1904616:BFF78_RS03365
uniprot id: A0A1D7Y3R7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1904616:BFF78 RS30040
gene id: 1904616:BFF78_RS30040
uniprot id: A0A1D7YGR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS28450
gene id: 1904616:BFF78_RS28450
uniprot id: A0A1D7YFR0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1904616:BFF78 RS31965
gene id: 1904616:BFF78_RS31965
uniprot id: A0A1D7YI84
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1904616:BFF78 RS13080
gene id: 1904616:BFF78_RS13080
uniprot id: A0A1D7Y8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS31875
gene id: 1904616:BFF78_RS31875
uniprot id: A0A1D7YHP3
names: Similarity
messages: Belongs to the IlvD/Edd family.

1904616:BFF78 RS01680
gene id: 1904616:BFF78_RS01680
uniprot id: A0A1D7Y2Z6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS14085
gene id: 1904616:BFF78_RS14085
uniprot id: A0A1D7Y8Z5
names: Similarity
messages: Belongs to the UPF0045 family.

1904616:BFF78 RS30770
gene id: 1904616:BFF78_RS30770
uniprot id: A0A1D7YH35
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1904616:BFF78 RS28950
gene id: 1904616:BFF78_RS28950
uniprot id: A0A1D7YGR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1904616:BFF78 RS14280
gene id: 1904616:BFF78_RS14280
uniprot id: A0A1D7Y926
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1904616:BFF78 RS40445
gene id: 1904616:BFF78_RS40445
uniprot id: A0A1D7YLM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1904616:BFF78 RS16545
gene id: 1904616:BFF78_RS16545
uniprot id: A0A1D7YAG4
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1904616:BFF78 RS19430
gene id: 1904616:BFF78_RS19430
uniprot id: A0A1D7YBT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1904616:BFF78 RS17580
gene id: 1904616:BFF78_RS17580
uniprot id: A0A1D7YAY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1904616:BFF78 RS10700
gene id: 1904616:BFF78_RS10700
uniprot id: A0A1D7Y7W5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS13735
gene id: 1904616:BFF78_RS13735
uniprot id: A0A1D7Y903
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1904616:BFF78 RS33310
gene id: 1904616:BFF78_RS33310
uniprot id: A0A1D7YIY6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1904616:BFF78 RS34215
gene id: 1904616:BFF78_RS34215
uniprot id: A0A1D7YIT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1904616:BFF78 RS09080
gene id: 1904616:BFF78_RS09080
uniprot id: A0A1D7Y6V0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS16390
gene id: 1904616:BFF78_RS16390
uniprot id: A0A1D7YA49
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1904616:BFF78 RS32520
gene id: 1904616:BFF78_RS32520
uniprot id: A0A1D7YIK2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1904616:BFF78 RS26440
gene id: 1904616:BFF78_RS26440
uniprot id: A0A1D7YES5
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS37945
gene id: 1904616:BFF78_RS37945
uniprot id: A0A1D7YKE1
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

1904616:BFF78 RS05185
gene id: 1904616:BFF78_RS05185
uniprot id: A0A1D7Y4K1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS18010
gene id: 1904616:BFF78_RS18010
uniprot id: A0A1D7YAQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS12685
gene id: 1904616:BFF78_RS12685
uniprot id: A0A1D7Y8A2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS36445
gene id: 1904616:BFF78_RS36445
uniprot id: A0A1D7YKF4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS17540
gene id: 1904616:BFF78_RS17540
uniprot id: A0A1D7YAG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1904616:BFF78 RS39125
gene id: 1904616:BFF78_RS39125
uniprot id: A0A1D7YKY8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS30160
gene id: 1904616:BFF78_RS30160
uniprot id: A0A1D7YHC4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS25490
gene id: 1904616:BFF78_RS25490
uniprot id: A0A1D7YEM0
names: Similarity
messages: Belongs to the peptidase C56 family.

1904616:BFF78 RS30060
gene id: 1904616:BFF78_RS30060
uniprot id: A0A1D7YHA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1904616:BFF78 RS26805
gene id: 1904616:BFF78_RS26805
uniprot id: A0A1D7YF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1904616:BFF78 RS06450
gene id: 1904616:BFF78_RS06450
uniprot id: A0A1D7Y582
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS04910
gene id: 1904616:BFF78_RS04910
uniprot id: A0A1D7YMV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS31565
gene id: 1904616:BFF78_RS31565
uniprot id: A0A1D7YHG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1904616:BFF78 RS19860
gene id: 1904616:BFF78_RS19860
uniprot id: A0A1D7YBL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS17830
gene id: 1904616:BFF78_RS17830
uniprot id: A0A1D7YAZ1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS13945
gene id: 1904616:BFF78_RS13945
uniprot id: A0A1D7Y955
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1904616:BFF78 RS14115
gene id: 1904616:BFF78_RS14115
uniprot id: A0A1D7Y8T3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS30450
gene id: 1904616:BFF78_RS30450
uniprot id: A0A1D7YPC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS24420
gene id: 1904616:BFF78_RS24420
uniprot id: A0A1D7YE20
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1904616:BFF78 RS23630
gene id: 1904616:BFF78_RS23630
uniprot id: A0A1D7YDR9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1904616:BFF78 RS23390
gene id: 1904616:BFF78_RS23390
uniprot id: A0A1D7YE54
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1904616:BFF78 RS08600
gene id: 1904616:BFF78_RS08600
uniprot id: A0A1D7Y6E4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1904616:BFF78 RS07355
gene id: 1904616:BFF78_RS07355
uniprot id: A0A1D7Y5Z5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS41845
gene id: 1904616:BFF78_RS41845
uniprot id: A0A1D7YMW2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1904616:BFF78 RS32940
gene id: 1904616:BFF78_RS32940
uniprot id: A0A1D7YI13
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1904616:BFF78 RS20805
gene id: 1904616:BFF78_RS20805
uniprot id: A0A1D7YC35
names: Similarity
messages: Belongs to the pirin family.

1904616:BFF78 RS08285
gene id: 1904616:BFF78_RS08285
uniprot id: A0A1D7Y6E2
names: Similarity
messages: Belongs to the GSP E family.

1904616:BFF78 RS02420
gene id: 1904616:BFF78_RS02420
uniprot id: A0A1D7Y3B1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1904616:BFF78 RS27320
gene id: 1904616:BFF78_RS27320
uniprot id: A0A1D7YG11
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS26405
gene id: 1904616:BFF78_RS26405
uniprot id: A0A1D7YEZ3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS29260
gene id: 1904616:BFF78_RS29260
uniprot id: A0A1D7YGF5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1904616:BFF78 RS32260
gene id: 1904616:BFF78_RS32260
uniprot id: A0A1D7YHU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1904616:BFF78 RS17815
gene id: 1904616:BFF78_RS17815
uniprot id: A0A1D7YAR0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS23750
gene id: 1904616:BFF78_RS23750
uniprot id: A0A1D7YDT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1904616:BFF78 RS33330
gene id: 1904616:BFF78_RS33330
uniprot id: A0A1D7YI70
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1904616:BFF78 RS19165
gene id: 1904616:BFF78_RS19165
uniprot id: A0A1D7YBD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1904616:BFF78 RS17845
gene id: 1904616:BFF78_RS17845
uniprot id: A0A1D7YAM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS37220
gene id: 1904616:BFF78_RS37220
uniprot id: A0A1D7YK29
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21435
gene id: 1904616:BFF78_RS21435
uniprot id: A0A1D7YCL3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1904616:BFF78 RS05825
gene id: 1904616:BFF78_RS05825
uniprot id: A0A1D7Y5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1904616:BFF78 RS17630
gene id: 1904616:BFF78_RS17630
uniprot id: A0A1D7YAW3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41420
gene id: 1904616:BFF78_RS41420
uniprot id: A0A1D7YM42
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1904616:BFF78 RS09125
gene id: 1904616:BFF78_RS09125
uniprot id: A0A1D7Y6E1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1904616:BFF78 RS24850
gene id: 1904616:BFF78_RS24850
uniprot id: A0A1D7YE73
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1904616:BFF78 RS17355
gene id: 1904616:BFF78_RS17355
uniprot id: A0A1D7YAD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS19270
gene id: 1904616:BFF78_RS19270
uniprot id: A0A1D7YBB5
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1904616:BFF78 RS36790
gene id: 1904616:BFF78_RS36790
uniprot id: A0A1D7YPN7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS32390
gene id: 1904616:BFF78_RS32390
uniprot id: A0A1D7YHQ6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1904616:BFF78 RS34235
gene id: 1904616:BFF78_RS34235
uniprot id: A0A1D7YIU6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1904616:BFF78 RS17430
gene id: 1904616:BFF78_RS17430
uniprot id: A0A1D7YAF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1904616:BFF78 RS27550
gene id: 1904616:BFF78_RS27550
uniprot id: A0A1D7YFA8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1904616:BFF78 RS14275
gene id: 1904616:BFF78_RS14275
uniprot id: A0A1D7Y9B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1904616:BFF78 RS14270
gene id: 1904616:BFF78_RS14270
uniprot id: A0A1D7Y9P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1904616:BFF78 RS17825
gene id: 1904616:BFF78_RS17825
uniprot id: A0A1D7YAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1904616:BFF78 RS26170
gene id: 1904616:BFF78_RS26170
uniprot id: A0A1D7YEN8
names: Similarity
messages: Belongs to the UPF0303 family.

1904616:BFF78 RS02825
gene id: 1904616:BFF78_RS02825
uniprot id: A0A1D7Y3K4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24765
gene id: 1904616:BFF78_RS24765
uniprot id: A0A1D7YDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1904616:BFF78 RS40685
gene id: 1904616:BFF78_RS40685
uniprot id: A0A1D7YM05
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1904616:BFF78 RS12640
gene id: 1904616:BFF78_RS12640
uniprot id: A0A1D7Y882
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1904616:BFF78 RS34400
gene id: 1904616:BFF78_RS34400
uniprot id: A0A1D7YIQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1904616:BFF78 RS26300
gene id: 1904616:BFF78_RS26300
uniprot id: A0A1D7YER2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS19805
gene id: 1904616:BFF78_RS19805
uniprot id: A0A1D7YBK1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21235
gene id: 1904616:BFF78_RS21235
uniprot id: A0A1D7YCK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1904616:BFF78 RS10805
gene id: 1904616:BFF78_RS10805
uniprot id: A0A1D7Y773
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS14795
gene id: 1904616:BFF78_RS14795
uniprot id: A0A1D7Y9B8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS17295
gene id: 1904616:BFF78_RS17295
uniprot id: A0A1D7YAQ3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1904616:BFF78 RS16380
gene id: 1904616:BFF78_RS16380
uniprot id: A0A1D7YA27
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS17400
gene id: 1904616:BFF78_RS17400
uniprot id: A0A1D7YAL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1904616:BFF78 RS26650
gene id: 1904616:BFF78_RS26650
uniprot id: A0A1D7YEW9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1904616:BFF78 RS09945
gene id: 1904616:BFF78_RS09945
uniprot id: A0A1D7Y6U5
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1904616:BFF78 RS31960
gene id: 1904616:BFF78_RS31960
uniprot id: A0A1D7YHG9
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1904616:BFF78 RS39465
gene id: 1904616:BFF78_RS39465
uniprot id: A0A1D7YLD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1904616:BFF78 RS25425
gene id: 1904616:BFF78_RS25425
uniprot id: A0A1D7YEA5
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1904616:BFF78 RS03070
gene id: 1904616:BFF78_RS03070
uniprot id: A0A1D7Y491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS31700
gene id: 1904616:BFF78_RS31700
uniprot id: A0A1D7YI27
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1904616:BFF78 RS07995
gene id: 1904616:BFF78_RS07995
uniprot id: A0A1D7Y5W9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1904616:BFF78 RS01805
gene id: 1904616:BFF78_RS01805
uniprot id: A0A1D7Y355
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1904616:BFF78 RS35220
gene id: 1904616:BFF78_RS35220
uniprot id: A0A1D7YJA7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS17230
gene id: 1904616:BFF78_RS17230
uniprot id: A0A1D7YAP4
names: Similarity
messages: Belongs to the YciI family.

1904616:BFF78 RS34725
gene id: 1904616:BFF78_RS34725
uniprot id: A0A1D7YIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1904616:BFF78 RS34950
gene id: 1904616:BFF78_RS34950
uniprot id: A0A1D7YJ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1904616:BFF78 RS06160
gene id: 1904616:BFF78_RS06160
uniprot id: A0A1D7Y4Z4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1904616:BFF78 RS32635
gene id: 1904616:BFF78_RS32635
uniprot id: A0A1D7YIL9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1904616:BFF78 RS28395
gene id: 1904616:BFF78_RS28395
uniprot id: A0A1D7YFP7
names: Similarity
messages: Belongs to the DapA family.

1904616:BFF78 RS19405
gene id: 1904616:BFF78_RS19405
uniprot id: A0A1D7YBK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1904616:BFF78 RS12735
gene id: 1904616:BFF78_RS12735
uniprot id: A0A1D7Y8Y0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1904616:BFF78 RS13935
gene id: 1904616:BFF78_RS13935
uniprot id: A0A1D7Y8Q0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1904616:BFF78 RS41530
gene id: 1904616:BFF78_RS41530
uniprot id: A0A1D7YM58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS31515
gene id: 1904616:BFF78_RS31515
uniprot id: A0A1D7YHA1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1904616:BFF78 RS30375
gene id: 1904616:BFF78_RS30375
uniprot id: A0A1D7YPG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1904616:BFF78 RS18740
gene id: 1904616:BFF78_RS18740
uniprot id: A0A1D7YB93
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1904616:BFF78 RS25735
gene id: 1904616:BFF78_RS25735
uniprot id: A0A1D7YEQ4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1904616:BFF78 RS39365
gene id: 1904616:BFF78_RS39365
uniprot id: A0A1D7YL44
names: Similarity
messages: Belongs to the peptidase M1 family.

1904616:BFF78 RS24145
gene id: 1904616:BFF78_RS24145
uniprot id: A0A1D7YEH1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21995
gene id: 1904616:BFF78_RS21995
uniprot id: A0A1D7YNS9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1904616:BFF78 RS06065
gene id: 1904616:BFF78_RS06065
uniprot id: A0A1D7Y510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS19275
gene id: 1904616:BFF78_RS19275
uniprot id: A0A1D7YC38
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS19450
gene id: 1904616:BFF78_RS19450
uniprot id: A0A1D7YC67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1904616:BFF78 RS07595
gene id: 1904616:BFF78_RS07595
uniprot id: A0A1D7Y5T5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS17495
gene id: 1904616:BFF78_RS17495
uniprot id: A0A1D7YAW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1904616:BFF78 RS03665
gene id: 1904616:BFF78_RS03665
uniprot id: A0A1D7Y3W2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS40865
gene id: 1904616:BFF78_RS40865
uniprot id: A0A1D7YLU9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS15425
gene id: 1904616:BFF78_RS15425
uniprot id: A0A1D7Y9L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS03950
gene id: 1904616:BFF78_RS03950
uniprot id: A0A1D7Y413
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS31060
gene id: 1904616:BFF78_RS31060
uniprot id: A0A1D7YH82
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS11510
gene id: 1904616:BFF78_RS11510
uniprot id: A0A1D7Y7Q3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS11170
gene id: 1904616:BFF78_RS11170
uniprot id: A0A1D7Y848
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1904616:BFF78 RS14705
gene id: 1904616:BFF78_RS14705
uniprot id: A0A1D7Y940
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1904616:BFF78 RS40030
gene id: 1904616:BFF78_RS40030
uniprot id: A0A1D7YLP3
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1904616:BFF78 RS15650
gene id: 1904616:BFF78_RS15650
uniprot id: A0A1D7YA16
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1904616:BFF78 RS27835
gene id: 1904616:BFF78_RS27835
uniprot id: A0A1D7YFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1904616:BFF78 RS11075
gene id: 1904616:BFF78_RS11075
uniprot id: A0A1D7Y7D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS29600
gene id: 1904616:BFF78_RS29600
uniprot id: A0A1D7YGB7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS04885
gene id: 1904616:BFF78_RS04885
uniprot id: A0A1D7Y4G2
names: Similarity
messages: Belongs to the universal stress protein A family.

1904616:BFF78 RS38695
gene id: 1904616:BFF78_RS38695
uniprot id: A0A1D7YKW9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS35280
gene id: 1904616:BFF78_RS35280
uniprot id: A0A1D7YJ66
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS10115
gene id: 1904616:BFF78_RS10115
uniprot id: A0A1D7Y6W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1904616:BFF78 RS11865
gene id: 1904616:BFF78_RS11865
uniprot id: A0A1D7Y827
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS29610
gene id: 1904616:BFF78_RS29610
uniprot id: A0A1D7YGA7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1904616:BFF78 RS05630
gene id: 1904616:BFF78_RS05630
uniprot id: A0A1D7Y4T1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS01865
gene id: 1904616:BFF78_RS01865
uniprot id: A0A1D7Y366
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1904616:BFF78 RS13150
gene id: 1904616:BFF78_RS13150
uniprot id: A0A1D7Y8Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1904616:BFF78 RS26465
gene id: 1904616:BFF78_RS26465
uniprot id: A0A1D7YF03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS11970
gene id: 1904616:BFF78_RS11970
uniprot id: A0A1D7Y844
names: Similarity
messages: Belongs to the citrate synthase family.

1904616:BFF78 RS01990
gene id: 1904616:BFF78_RS01990
uniprot id: A0A1D7Y3H9
names: Similarity
messages: Belongs to the NodU/CmcH family.

1904616:BFF78 RS04420
gene id: 1904616:BFF78_RS04420
uniprot id: A0A1D7Y489
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1904616:BFF78 RS12110
gene id: 1904616:BFF78_RS12110
uniprot id: A0A1D7Y7U1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1904616:BFF78 RS07095
gene id: 1904616:BFF78_RS07095
uniprot id: A0A1D7Y5I9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS18560
gene id: 1904616:BFF78_RS18560
uniprot id: A0A1D7YB67
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1904616:BFF78 RS31020
gene id: 1904616:BFF78_RS31020
uniprot id: A0A1D7YH10
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1904616:BFF78 RS30730
gene id: 1904616:BFF78_RS30730
uniprot id: A0A1D7YPT7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS39445
gene id: 1904616:BFF78_RS39445
uniprot id: A0A1D7YLA1
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1904616:BFF78 RS37910
gene id: 1904616:BFF78_RS37910
uniprot id: A0A1D7YKL7
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1904616:BFF78 RS40570
gene id: 1904616:BFF78_RS40570
uniprot id: A0A1D7YLT6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS12815
gene id: 1904616:BFF78_RS12815
uniprot id: A0A1D7Y876
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS22205
gene id: 1904616:BFF78_RS22205
uniprot id: A0A1D7YDK5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS18290
gene id: 1904616:BFF78_RS18290
uniprot id: A0A1D7YAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1904616:BFF78 RS32285
gene id: 1904616:BFF78_RS32285
uniprot id: A0A1D7YIE9
names: Similarity
messages: Belongs to the peptidase U62 family.

1904616:BFF78 RS49535
gene id: 1904616:BFF78_RS49535
uniprot id: A0A1D7YET7
names: Similarity
messages: Belongs to the CdaR family.

1904616:BFF78 RS21500
gene id: 1904616:BFF78_RS21500
uniprot id: A0A1D7YCG3
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1904616:BFF78 RS13740
gene id: 1904616:BFF78_RS13740
uniprot id: A0A1D7Y8L9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1904616:BFF78 RS22505
gene id: 1904616:BFF78_RS22505
uniprot id: A0A1D7YCW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS03820
gene id: 1904616:BFF78_RS03820
uniprot id: A0A1D7Y3Y1
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

1904616:BFF78 RS15850
gene id: 1904616:BFF78_RS15850
uniprot id: A0A1D7Y9P0
names: Similarity
messages: Belongs to the FBPase class 2 family.

1904616:BFF78 RS39915
gene id: 1904616:BFF78_RS39915
uniprot id: A0A1D7YLI1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1904616:BFF78 RS01720
gene id: 1904616:BFF78_RS01720
uniprot id: A0A1D7Y3K9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS36975
gene id: 1904616:BFF78_RS36975
uniprot id: A0A1D7YPR2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1904616:BFF78 RS28820
gene id: 1904616:BFF78_RS28820
uniprot id: A0A1D7YGP7
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1904616:BFF78 RS11875
gene id: 1904616:BFF78_RS11875
uniprot id: A0A1D7Y7Q2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1904616:BFF78 RS37095
gene id: 1904616:BFF78_RS37095
uniprot id: A0A1D7YK65
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS13650
gene id: 1904616:BFF78_RS13650
uniprot id: A0A1D7Y8K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS11880
gene id: 1904616:BFF78_RS11880
uniprot id: A0A1D7Y8I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS35645
gene id: 1904616:BFF78_RS35645
uniprot id: A0A1D7YJH1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS28525
gene id: 1904616:BFF78_RS28525
uniprot id: A0A1D7YFY5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41255
gene id: 1904616:BFF78_RS41255
uniprot id: A0A1D7YM11
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS29790
gene id: 1904616:BFF78_RS29790
uniprot id: A0A1D7YP86
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS36670
gene id: 1904616:BFF78_RS36670
uniprot id: A0A1D7YJZ5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21610
gene id: 1904616:BFF78_RS21610
uniprot id: A0A1D7YCH7
names: Similarity
messages: Belongs to the SCO1/2 family.

1904616:BFF78 RS06375
gene id: 1904616:BFF78_RS06375
uniprot id: A0A1D7Y551
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1904616:BFF78 RS35050
gene id: 1904616:BFF78_RS35050
uniprot id: A0A1D7YJ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1904616:BFF78 RS10400
gene id: 1904616:BFF78_RS10400
uniprot id: A0A1D7Y712
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS22710
gene id: 1904616:BFF78_RS22710
uniprot id: A0A1D7YDB6
names: Similarity
messages: Belongs to the CsoR family.

1904616:BFF78 RS39385
gene id: 1904616:BFF78_RS39385
uniprot id: A0A1D7YLR4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS31310
gene id: 1904616:BFF78_RS31310
uniprot id: A0A1D7YH68
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS17550
gene id: 1904616:BFF78_RS17550
uniprot id: A0A1D7YAY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1904616:BFF78 RS33460
gene id: 1904616:BFF78_RS33460
uniprot id: A0A1D7YIA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS41860
gene id: 1904616:BFF78_RS41860
uniprot id: A0A1D7YMF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1904616:BFF78 RS15540
gene id: 1904616:BFF78_RS15540
uniprot id: A0A1D7Y9X5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1904616:BFF78 RS12150
gene id: 1904616:BFF78_RS12150
uniprot id: A0A1D7Y7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1904616:BFF78 RS49575
gene id: 1904616:BFF78_RS49575
uniprot id: A0A1D7YJU3
names: Similarity
messages: Belongs to the Nudix hydrolase family.
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1904616:BFF78 RS01885
gene id: 1904616:BFF78_RS01885
uniprot id: A0A1D7Y349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

1904616:BFF78 RS41790
gene id: 1904616:BFF78_RS41790
uniprot id: A0A1D7YMI7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1904616:BFF78 RS10380
gene id: 1904616:BFF78_RS10380
uniprot id: A0A1D7Y7Q5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1904616:BFF78 RS10565
gene id: 1904616:BFF78_RS10565
uniprot id: A0A1D7Y756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS35785
gene id: 1904616:BFF78_RS35785
uniprot id: A0A1D7YJF6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS17340
gene id: 1904616:BFF78_RS17340
uniprot id: A0A1D7YAI2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1904616:BFF78 RS35440
gene id: 1904616:BFF78_RS35440
uniprot id: A0A1D7YJE8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS34360
gene id: 1904616:BFF78_RS34360
uniprot id: A0A1D7YIW2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS28405
gene id: 1904616:BFF78_RS28405
uniprot id: A0A1D7YG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS01325
gene id: 1904616:BFF78_RS01325
uniprot id: A0A1D7Y389
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS18025
gene id: 1904616:BFF78_RS18025
uniprot id: A0A1D7YAP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS21220
gene id: 1904616:BFF78_RS21220
uniprot id: A0A1D7YCF6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1904616:BFF78 RS23720
gene id: 1904616:BFF78_RS23720
uniprot id: A0A1D7YDP2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS33455
gene id: 1904616:BFF78_RS33455
uniprot id: A0A1D7YIE7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS22995
gene id: 1904616:BFF78_RS22995
uniprot id: A0A1D7YD43
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS35205
gene id: 1904616:BFF78_RS35205
uniprot id: A0A1D7YPN6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS33225
gene id: 1904616:BFF78_RS33225
uniprot id: A0A1D7YIC5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS38840
gene id: 1904616:BFF78_RS38840
uniprot id: A0A1D7YKU5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS17405
gene id: 1904616:BFF78_RS17405
uniprot id: A0A1D7YAE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1904616:BFF78 RS26520
gene id: 1904616:BFF78_RS26520
uniprot id: A0A1D7YFL9
names: Similarity
messages: Belongs to the universal stress protein A family.

1904616:BFF78 RS17160
gene id: 1904616:BFF78_RS17160
uniprot id: A0A1D7YAF2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1904616:BFF78 RS13955
gene id: 1904616:BFF78_RS13955
uniprot id: A0A1D7Y8X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1904616:BFF78 RS14595
gene id: 1904616:BFF78_RS14595
uniprot id: A0A1D7Y932
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1904616:BFF78 RS39780
gene id: 1904616:BFF78_RS39780
uniprot id: A0A1D7YLA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS14505
gene id: 1904616:BFF78_RS14505
uniprot id: A0A1D7Y962
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1904616:BFF78 RS38855
gene id: 1904616:BFF78_RS38855
uniprot id: A0A1D7YKW2
names: Similarity
messages: Belongs to the AHA1 family.

1904616:BFF78 RS04995
gene id: 1904616:BFF78_RS04995
uniprot id: A0A1D7Y4L5
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1904616:BFF78 RS31950
gene id: 1904616:BFF78_RS31950
uniprot id: A0A1D7YHP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1904616:BFF78 RS20480
gene id: 1904616:BFF78_RS20480
uniprot id: A0A1D7YC70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1904616:BFF78 RS41995
gene id: 1904616:BFF78_RS41995
uniprot id: A0A1D7YML5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1904616:BFF78 RS04465
gene id: 1904616:BFF78_RS04465
uniprot id: A0A1D7Y492
names: Similarity
messages: Belongs to the universal stress protein A family.

1904616:BFF78 RS06705
gene id: 1904616:BFF78_RS06705
uniprot id: A0A1D7Y593
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1904616:BFF78 RS29110
gene id: 1904616:BFF78_RS29110
uniprot id: A0A1D7YG20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1904616:BFF78 RS16440
gene id: 1904616:BFF78_RS16440
uniprot id: A0A1D7YA37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1904616:BFF78 RS21210
gene id: 1904616:BFF78_RS21210
uniprot id: A0A1D7YD38
names: Similarity
messages: Belongs to the UPF0232 family.

1904616:BFF78 RS05820
gene id: 1904616:BFF78_RS05820
uniprot id: A0A1D7Y4V6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS37855
gene id: 1904616:BFF78_RS37855
uniprot id: A0A1D7YPV3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1904616:BFF78 RS35435
gene id: 1904616:BFF78_RS35435
uniprot id: A0A1D7YJ84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1904616:BFF78 RS41850
gene id: 1904616:BFF78_RS41850
uniprot id: A0A1D7YME9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1904616:BFF78 RS18425
gene id: 1904616:BFF78_RS18425
uniprot id: A0A1D7YBD4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1904616:BFF78 RS46285
gene id: 1904616:BFF78_RS46285
uniprot id: A0A1D7YCH3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS36705
gene id: 1904616:BFF78_RS36705
uniprot id: A0A1D7YKJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1904616:BFF78 RS07130
gene id: 1904616:BFF78_RS07130
uniprot id: A0A1D7Y5Q9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS19020
gene id: 1904616:BFF78_RS19020
uniprot id: A0A1D7YB70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS27625
gene id: 1904616:BFF78_RS27625
uniprot id: A0A1D7YFB6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS14090
gene id: 1904616:BFF78_RS14090
uniprot id: A0A1D7Y8T4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS32245
gene id: 1904616:BFF78_RS32245
uniprot id: A0A1D7YHU1
names: Similarity
messages: Belongs to the peptidase S8 family.

1904616:BFF78 RS35760
gene id: 1904616:BFF78_RS35760
uniprot id: A0A1D7YJL8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS23825
gene id: 1904616:BFF78_RS23825
uniprot id: A0A1D7YDJ0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1904616:BFF78 RS41060
gene id: 1904616:BFF78_RS41060
uniprot id: A0A1D7YQ36
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1904616:BFF78 RS30045
gene id: 1904616:BFF78_RS30045
uniprot id: A0A1D7YGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS09265
gene id: 1904616:BFF78_RS09265
uniprot id: A0A1D7Y6L0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1904616:BFF78 RS39065
gene id: 1904616:BFF78_RS39065
uniprot id: A0A1D7YL61
names: Similarity
messages: Belongs to the peptidase S33 family.

1904616:BFF78 RS09680
gene id: 1904616:BFF78_RS09680
uniprot id: A0A1D7Y6S4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1904616:BFF78 RS12675
gene id: 1904616:BFF78_RS12675
uniprot id: A0A1D7Y8X2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1904616:BFF78 RS34015
gene id: 1904616:BFF78_RS34015
uniprot id: A0A1D7YIQ0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1904616:BFF78 RS04610
gene id: 1904616:BFF78_RS04610
uniprot id: A0A1D7Y4B1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1904616:BFF78 RS30185
gene id: 1904616:BFF78_RS30185
uniprot id: A0A1D7YGU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1904616:BFF78 RS32420
gene id: 1904616:BFF78_RS32420
uniprot id: A0A1D7YHR5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1904616:BFF78 RS15575
gene id: 1904616:BFF78_RS15575
uniprot id: A0A1D7YNK1
names: Similarity
messages: Belongs to the serpin family.

1904616:BFF78 RS27510
gene id: 1904616:BFF78_RS27510
uniprot id: A0A1D7YF97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS39395
gene id: 1904616:BFF78_RS39395
uniprot id: A0A1D7YL96
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41065
gene id: 1904616:BFF78_RS41065
uniprot id: A0A1D7YLZ4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1904616:BFF78 RS18805
gene id: 1904616:BFF78_RS18805
uniprot id: A0A1D7YB38
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS08635
gene id: 1904616:BFF78_RS08635
uniprot id: A0A1D7Y6A4
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

1904616:BFF78 RS06400
gene id: 1904616:BFF78_RS06400
uniprot id: A0A1D7Y535
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1904616:BFF78 RS14265
gene id: 1904616:BFF78_RS14265
uniprot id: A0A1D7Y8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1904616:BFF78 RS04495
gene id: 1904616:BFF78_RS04495
uniprot id: A0A1D7Y4P5
names: Similarity
messages: Belongs to the thioesterase family.

1904616:BFF78 RS16180
gene id: 1904616:BFF78_RS16180
uniprot id: A0A1D7YA19
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS29905
gene id: 1904616:BFF78_RS29905
uniprot id: A0A1D7YGH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS14295
gene id: 1904616:BFF78_RS14295
uniprot id: A0A1D7Y996
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS14180
gene id: 1904616:BFF78_RS14180
uniprot id: A0A1D7Y908
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1904616:BFF78 RS15635
gene id: 1904616:BFF78_RS15635
uniprot id: A0A1D7Y9K5
names: Similarity
messages: Belongs to the thioesterase family.

1904616:BFF78 RS03565
gene id: 1904616:BFF78_RS03565
uniprot id: A0A1D7Y3V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1904616:BFF78 RS02140
gene id: 1904616:BFF78_RS02140
uniprot id: A0A1D7Y360
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1904616:BFF78 RS17200
gene id: 1904616:BFF78_RS17200
uniprot id: A0A1D7YB55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1904616:BFF78 RS23730
gene id: 1904616:BFF78_RS23730
uniprot id: A0A1D7YDI3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS05885
gene id: 1904616:BFF78_RS05885
uniprot id: A0A1D7Y5B4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1904616:BFF78 RS11545
gene id: 1904616:BFF78_RS11545
uniprot id: A0A1D7Y7J4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24510
gene id: 1904616:BFF78_RS24510
uniprot id: A0A1D7YDU7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS38465
gene id: 1904616:BFF78_RS38465
uniprot id: A0A1D7YKN4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1904616:BFF78 RS04635
gene id: 1904616:BFF78_RS04635
uniprot id: A0A1D7Y4B4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS38270
gene id: 1904616:BFF78_RS38270
uniprot id: A0A1D7YQ52
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1904616:BFF78 RS17450
gene id: 1904616:BFF78_RS17450
uniprot id: A0A1D7YAK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1904616:BFF78 RS10795
gene id: 1904616:BFF78_RS10795
uniprot id: A0A1D7Y7H7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS03355
gene id: 1904616:BFF78_RS03355
uniprot id: A0A1D7Y3U9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS20065
gene id: 1904616:BFF78_RS20065
uniprot id: A0A1D7YBU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1904616:BFF78 RS27750
gene id: 1904616:BFF78_RS27750
uniprot id: A0A1D7YFQ4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1904616:BFF78 RS14390
gene id: 1904616:BFF78_RS14390
uniprot id: A0A1D7YNF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1904616:BFF78 RS40825
gene id: 1904616:BFF78_RS40825
uniprot id: A0A1D7YLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS12765
gene id: 1904616:BFF78_RS12765
uniprot id: A0A1D7Y871
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1904616:BFF78 RS14675
gene id: 1904616:BFF78_RS14675
uniprot id: A0A1D7Y9I0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1904616:BFF78 RS21020
gene id: 1904616:BFF78_RS21020
uniprot id: A0A1D7YC71
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS09415
gene id: 1904616:BFF78_RS09415
uniprot id: A0A1D7YN07
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS28410
gene id: 1904616:BFF78_RS28410
uniprot id: A0A1D7YFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS14005
gene id: 1904616:BFF78_RS14005
uniprot id: A0A1D7Y9J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS34420
gene id: 1904616:BFF78_RS34420
uniprot id: A0A1D7YIY7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1904616:BFF78 RS20790
gene id: 1904616:BFF78_RS20790
uniprot id: A0A1D7YC32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS25720
gene id: 1904616:BFF78_RS25720
uniprot id: A0A1D7YEF6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1904616:BFF78 RS10430
gene id: 1904616:BFF78_RS10430
uniprot id: A0A1D7YN39
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS13270
gene id: 1904616:BFF78_RS13270
uniprot id: A0A1D7Y8S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1904616:BFF78 RS25970
gene id: 1904616:BFF78_RS25970
uniprot id: A0A1D7YEW0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS12985
gene id: 1904616:BFF78_RS12985
uniprot id: A0A1D7Y8F5
names: Similarity
messages: Belongs to the UPF0102 family.

1904616:BFF78 RS11610
gene id: 1904616:BFF78_RS11610
uniprot id: A0A1D7Y7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1904616:BFF78 RS17455
gene id: 1904616:BFF78_RS17455
uniprot id: A0A1D7YAM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1904616:BFF78 RS28275
gene id: 1904616:BFF78_RS28275
uniprot id: A0A1D7YFM8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS25350
gene id: 1904616:BFF78_RS25350
uniprot id: A0A1D7YF20
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS00345
gene id: 1904616:BFF78_RS00345
uniprot id: A0A1D7Y2H1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1904616:BFF78 RS10200
gene id: 1904616:BFF78_RS10200
uniprot id: A0A1D7Y6Y2
names: Similarity
messages: Belongs to the hyi family.

1904616:BFF78 RS15320
gene id: 1904616:BFF78_RS15320
uniprot id: A0A1D7Y9F2
names: Similarity
messages: Belongs to the UPF0162 family.

1904616:BFF78 RS29935
gene id: 1904616:BFF78_RS29935
uniprot id: A0A1D7YGF4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34680
gene id: 1904616:BFF78_RS34680
uniprot id: A0A1D7YIW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1904616:BFF78 RS24635
gene id: 1904616:BFF78_RS24635
uniprot id: A0A1D7YEQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1904616:BFF78 RS38990
gene id: 1904616:BFF78_RS38990
uniprot id: A0A1D7YL37
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1904616:BFF78 RS14475
gene id: 1904616:BFF78_RS14475
uniprot id: A0A1D7Y901
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1904616:BFF78 RS25525
gene id: 1904616:BFF78_RS25525
uniprot id: A0A1D7YEI6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS29085
gene id: 1904616:BFF78_RS29085
uniprot id: A0A1D7YGA1
names: Similarity
messages: Belongs to the aldose epimerase family.

1904616:BFF78 RS11300
gene id: 1904616:BFF78_RS11300
uniprot id: A0A1D7Y7J5
names: Similarity
messages: Belongs to the thioesterase family.

1904616:BFF78 RS14335
gene id: 1904616:BFF78_RS14335
uniprot id: A0A1D7Y944
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1904616:BFF78 RS38785
gene id: 1904616:BFF78_RS38785
uniprot id: A0A1D7YKT6
names: Similarity
messages: Belongs to the asparagine synthetase family.

1904616:BFF78 RS17020
gene id: 1904616:BFF78_RS17020
uniprot id: A0A1D7YA75
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS30210
gene id: 1904616:BFF78_RS30210
uniprot id: A0A1D7YGL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1904616:BFF78 RS37200
gene id: 1904616:BFF78_RS37200
uniprot id: A0A1D7YK86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS09155
gene id: 1904616:BFF78_RS09155
uniprot id: A0A1D7Y6I2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1904616:BFF78 RS13120
gene id: 1904616:BFF78_RS13120
uniprot id: A0A1D7Y8A9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1904616:BFF78 RS36460
gene id: 1904616:BFF78_RS36460
uniprot id: A0A1D7YJX7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1904616:BFF78 RS15865
gene id: 1904616:BFF78_RS15865
uniprot id: A0A1D7Y9N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1904616:BFF78 RS17570
gene id: 1904616:BFF78_RS17570
uniprot id: A0A1D7YAV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1904616:BFF78 RS34220
gene id: 1904616:BFF78_RS34220
uniprot id: A0A1D7YIM6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS30600
gene id: 1904616:BFF78_RS30600
uniprot id: A0A1D7YGU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1904616:BFF78 RS25515
gene id: 1904616:BFF78_RS25515
uniprot id: A0A1D7YEP3
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1904616:BFF78 RS21160
gene id: 1904616:BFF78_RS21160
uniprot id: A0A1D7YCP7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS29675
gene id: 1904616:BFF78_RS29675
uniprot id: A0A1D7YGB9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS49520
gene id: 1904616:BFF78_RS49520
uniprot id: A0A1D7Y6L9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS33285
gene id: 1904616:BFF78_RS33285
uniprot id: A0A1D7YI76
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS36020
gene id: 1904616:BFF78_RS36020
uniprot id: A0A1D7YJP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1904616:BFF78 RS32485
gene id: 1904616:BFF78_RS32485
uniprot id: A0A1D7YHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1904616:BFF78 RS19195
gene id: 1904616:BFF78_RS19195
uniprot id: A0A1D7YBA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS39455
gene id: 1904616:BFF78_RS39455
uniprot id: A0A1D7YLE3
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1904616:BFF78 RS15435
gene id: 1904616:BFF78_RS15435
uniprot id: A0A1D7Y9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS03875
gene id: 1904616:BFF78_RS03875
uniprot id: A0A1D7Y3Z0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS12940
gene id: 1904616:BFF78_RS12940
uniprot id: A0A1D7YND3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1904616:BFF78 RS25945
gene id: 1904616:BFF78_RS25945
uniprot id: A0A1D7YEJ8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1904616:BFF78 RS34415
gene id: 1904616:BFF78_RS34415
uniprot id: A0A1D7YIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1904616:BFF78 RS20625
gene id: 1904616:BFF78_RS20625
uniprot id: A0A1D7YC02
names: Similarity
messages: Belongs to the group II decarboxylase family.

1904616:BFF78 RS25295
gene id: 1904616:BFF78_RS25295
uniprot id: A0A1D7YE80
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

1904616:BFF78 RS26790
gene id: 1904616:BFF78_RS26790
uniprot id: A0A1D7YEY6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1904616:BFF78 RS12415
gene id: 1904616:BFF78_RS12415
uniprot id: A0A1D7Y8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1904616:BFF78 RS18045
gene id: 1904616:BFF78_RS18045
uniprot id: A0A1D7YAX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS11270
gene id: 1904616:BFF78_RS11270
uniprot id: A0A1D7Y7D7
names: Similarity
messages: Belongs to the thioesterase family.

1904616:BFF78 RS04625
gene id: 1904616:BFF78_RS04625
uniprot id: A0A1D7YMV6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1904616:BFF78 RS34435
gene id: 1904616:BFF78_RS34435
uniprot id: A0A1D7YIX8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS40945
gene id: 1904616:BFF78_RS40945
uniprot id: A0A1D7YM08
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS31080
gene id: 1904616:BFF78_RS31080
uniprot id: A0A1D7YH19
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS36425
gene id: 1904616:BFF78_RS36425
uniprot id: A0A1D7YJV3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS39540
gene id: 1904616:BFF78_RS39540
uniprot id: A0A1D7YL88
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS41180
gene id: 1904616:BFF78_RS41180
uniprot id: A0A1D7YM80
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1904616:BFF78 RS49560
gene id: 1904616:BFF78_RS49560
uniprot id: A0A1D7YDN2
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS24310
gene id: 1904616:BFF78_RS24310
uniprot id: A0A1D7YP22
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS23225
gene id: 1904616:BFF78_RS23225
uniprot id: A0A1D7YE26
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS11740
gene id: 1904616:BFF78_RS11740
uniprot id: A0A1D7Y7P8
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1904616:BFF78 RS05480
gene id: 1904616:BFF78_RS05480
uniprot id: A0A1D7Y4Q0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS22885
gene id: 1904616:BFF78_RS22885
uniprot id: A0A1D7YDW4
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1904616:BFF78 RS21265
gene id: 1904616:BFF78_RS21265
uniprot id: A0A1D7YCR5
names: Similarity
messages: Belongs to the ParB family.

1904616:BFF78 RS35905
gene id: 1904616:BFF78_RS35905
uniprot id: A0A1D7YJM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1904616:BFF78 RS10500
gene id: 1904616:BFF78_RS10500
uniprot id: A0A1D7Y7S4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS39135
gene id: 1904616:BFF78_RS39135
uniprot id: A0A1D7YL08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS25070
gene id: 1904616:BFF78_RS25070
uniprot id: A0A1D7YE53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1904616:BFF78 RS14065
gene id: 1904616:BFF78_RS14065
uniprot id: A0A1D7Y9K4
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1904616:BFF78 RS21225
gene id: 1904616:BFF78_RS21225
uniprot id: A0A1D7YCH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1904616:BFF78 RS17485
gene id: 1904616:BFF78_RS17485
uniprot id: A0A1D7YAG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1904616:BFF78 RS30275
gene id: 1904616:BFF78_RS30275
uniprot id: A0A1D7YGL6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1904616:BFF78 RS33095
gene id: 1904616:BFF78_RS33095
uniprot id: A0A1D7YI32
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1904616:BFF78 RS31640
gene id: 1904616:BFF78_RS31640
uniprot id: A0A1D7YHB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1904616:BFF78 RS12115
gene id: 1904616:BFF78_RS12115
uniprot id: A0A1D7YNF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1904616:BFF78 RS29035
gene id: 1904616:BFF78_RS29035
uniprot id: A0A1D7YGB5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1904616:BFF78 RS32650
gene id: 1904616:BFF78_RS32650
uniprot id: A0A1D7YI25
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1904616:BFF78 RS38995
gene id: 1904616:BFF78_RS38995
uniprot id: A0A1D7YL13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS17805
gene id: 1904616:BFF78_RS17805
uniprot id: A0A1D7YBF6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS30120
gene id: 1904616:BFF78_RS30120
uniprot id: A0A1D7YGR9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1904616:BFF78 RS03990
gene id: 1904616:BFF78_RS03990
uniprot id: A0A1D7Y420
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS30750
gene id: 1904616:BFF78_RS30750
uniprot id: A0A1D7YH32
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS18390
gene id: 1904616:BFF78_RS18390
uniprot id: A0A1D7YAW7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS38765
gene id: 1904616:BFF78_RS38765
uniprot id: A0A1D7YKZ9
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1904616:BFF78 RS05490
gene id: 1904616:BFF78_RS05490
uniprot id: A0A1D7Y4V4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1904616:BFF78 RS27860
gene id: 1904616:BFF78_RS27860
uniprot id: A0A1D7YFG8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS09585
gene id: 1904616:BFF78_RS09585
uniprot id: A0A1D7YN55
names: Similarity
messages: Belongs to the asp23 family.

1904616:BFF78 RS19810
gene id: 1904616:BFF78_RS19810
uniprot id: A0A1D7YBK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1904616:BFF78 RS11890
gene id: 1904616:BFF78_RS11890
uniprot id: A0A1D7Y7X5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1904616:BFF78 RS24930
gene id: 1904616:BFF78_RS24930
uniprot id: A0A1D7YE16
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1904616:BFF78 RS10710
gene id: 1904616:BFF78_RS10710
uniprot id: A0A1D7Y7B2
names: Similarity
messages: Belongs to the terpene synthase family.

1904616:BFF78 RS16410
gene id: 1904616:BFF78_RS16410
uniprot id: A0A1D7YAD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1904616:BFF78 RS32670
gene id: 1904616:BFF78_RS32670
uniprot id: A0A1D7YI10
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1904616:BFF78 RS02160
gene id: 1904616:BFF78_RS02160
uniprot id: A0A1D7Y3A5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS12995
gene id: 1904616:BFF78_RS12995
uniprot id: A0A1D7Y8A6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1904616:BFF78 RS30905
gene id: 1904616:BFF78_RS30905
uniprot id: A0A1D7YGZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS06905
gene id: 1904616:BFF78_RS06905
uniprot id: A0A1D7Y5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1904616:BFF78 RS36365
gene id: 1904616:BFF78_RS36365
uniprot id: A0A1D7YJP8
names: Similarity
messages: Belongs to the peptidase S66 family.

1904616:BFF78 RS13460
gene id: 1904616:BFF78_RS13460
uniprot id: A0A1D7Y8H3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1904616:BFF78 RS34440
gene id: 1904616:BFF78_RS34440
uniprot id: A0A1D7YIR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1904616:BFF78 RS27045
gene id: 1904616:BFF78_RS27045
uniprot id: A0A1D7YFD5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS03300
gene id: 1904616:BFF78_RS03300
uniprot id: A0A1D7Y3Q5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1904616:BFF78 RS30320
gene id: 1904616:BFF78_RS30320
uniprot id: A0A1D7YGW6
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1904616:BFF78 RS11395
gene id: 1904616:BFF78_RS11395
uniprot id: A0A1D7Y7X6
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

1904616:BFF78 RS07030
gene id: 1904616:BFF78_RS07030
uniprot id: A0A1D7Y5E7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1904616:BFF78 RS17460
gene id: 1904616:BFF78_RS17460
uniprot id: A0A1D7YAF5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1904616:BFF78 RS40730
gene id: 1904616:BFF78_RS40730
uniprot id: A0A1D7YLX1
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1904616:BFF78 RS32100
gene id: 1904616:BFF78_RS32100
uniprot id: A0A1D7YHR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1904616:BFF78 RS16920
gene id: 1904616:BFF78_RS16920
uniprot id: A0A1D7YAM0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1904616:BFF78 RS33400
gene id: 1904616:BFF78_RS33400
uniprot id: A0A1D7YID6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS05930
gene id: 1904616:BFF78_RS05930
uniprot id: A0A1D7Y5L3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS02120
gene id: 1904616:BFF78_RS02120
uniprot id: A0A1D7Y3R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS04650
gene id: 1904616:BFF78_RS04650
uniprot id: A0A1D7Y4E8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS34645
gene id: 1904616:BFF78_RS34645
uniprot id: A0A1D7YJ02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1904616:BFF78 RS15960
gene id: 1904616:BFF78_RS15960
uniprot id: A0A1D7YA55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS17260
gene id: 1904616:BFF78_RS17260
uniprot id: A0A1D7YAB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1904616:BFF78 RS24885
gene id: 1904616:BFF78_RS24885
uniprot id: A0A1D7YET2
names: Similarity
messages: Belongs to the CFA/CMAS family.

1904616:BFF78 RS21280
gene id: 1904616:BFF78_RS21280
uniprot id: A0A1D7YCC0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1904616:BFF78 RS28070
gene id: 1904616:BFF78_RS28070
uniprot id: A0A1D7YFS8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS24120
gene id: 1904616:BFF78_RS24120
uniprot id: A0A1D7YE02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1904616:BFF78 RS16155
gene id: 1904616:BFF78_RS16155
uniprot id: A0A1D7Y9U2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS32140
gene id: 1904616:BFF78_RS32140
uniprot id: A0A1D7YHU2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS19350
gene id: 1904616:BFF78_RS19350
uniprot id: A0A1D7YBD0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1904616:BFF78 RS21320
gene id: 1904616:BFF78_RS21320
uniprot id: A0A1D7YCH4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1904616:BFF78 RS39905
gene id: 1904616:BFF78_RS39905
uniprot id: A0A1D7YM02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

1904616:BFF78 RS13015
gene id: 1904616:BFF78_RS13015
uniprot id: A0A1D7Y893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1904616:BFF78 RS35915
gene id: 1904616:BFF78_RS35915
uniprot id: A0A1D7Y355
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1904616:BFF78 RS23200
gene id: 1904616:BFF78_RS23200
uniprot id: A0A1D7YDH4
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS11795
gene id: 1904616:BFF78_RS11795
uniprot id: A0A1D7Y7Q9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS25780
gene id: 1904616:BFF78_RS25780
uniprot id: A0A1D7YEG7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS39460
gene id: 1904616:BFF78_RS39460
uniprot id: A0A1D7YL62
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1904616:BFF78 RS31685
gene id: 1904616:BFF78_RS31685
uniprot id: A0A1D7YHJ5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1904616:BFF78 RS29350
gene id: 1904616:BFF78_RS29350
uniprot id: A0A1D7YGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1904616:BFF78 RS13755
gene id: 1904616:BFF78_RS13755
uniprot id: A0A1D7Y8M6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS27795
gene id: 1904616:BFF78_RS27795
uniprot id: A0A1D7YFF8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1904616:BFF78 RS20045
gene id: 1904616:BFF78_RS20045
uniprot id: A0A1D7YBP4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS33720
gene id: 1904616:BFF78_RS33720
uniprot id: A0A1D7YIM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1904616:BFF78 RS35765
gene id: 1904616:BFF78_RS35765
uniprot id: A0A1D7YJF0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1904616:BFF78 RS23675
gene id: 1904616:BFF78_RS23675
uniprot id: A0A1D7YDP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS05430
gene id: 1904616:BFF78_RS05430
uniprot id: A0A1D7Y4N4
names: Similarity
messages: Belongs to the TPP enzyme family.

1904616:BFF78 RS17905
gene id: 1904616:BFF78_RS17905
uniprot id: A0A1D7YAN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1904616:BFF78 RS35495
gene id: 1904616:BFF78_RS35495
uniprot id: A0A1D7YJF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1904616:BFF78 RS30945
gene id: 1904616:BFF78_RS30945
uniprot id: A0A1D7YH05
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS02455
gene id: 1904616:BFF78_RS02455
uniprot id: A0A1D7Y3B9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1904616:BFF78 RS04515
gene id: 1904616:BFF78_RS04515
uniprot id: A0A1D7Y494
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS35035
gene id: 1904616:BFF78_RS35035
uniprot id: A0A1D7YJ27
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1904616:BFF78 RS36750
gene id: 1904616:BFF78_RS36750
uniprot id: A0A1D7YK02
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS35565
gene id: 1904616:BFF78_RS35565
uniprot id: A0A1D7YJB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1904616:BFF78 RS26715
gene id: 1904616:BFF78_RS26715
uniprot id: A0A1D7YPA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1904616:BFF78 RS24430
gene id: 1904616:BFF78_RS24430
uniprot id: A0A1D7YE50
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1904616:BFF78 RS34155
gene id: 1904616:BFF78_RS34155
uniprot id: A0A1D7YIL8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1904616:BFF78 RS17375
gene id: 1904616:BFF78_RS17375
uniprot id: A0A1D7YAE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1904616:BFF78 RS06975
gene id: 1904616:BFF78_RS06975
uniprot id: A0A1D7Y623
names: Similarity
messages: Belongs to the HIBADH-related family.

1904616:BFF78 RS33240
gene id: 1904616:BFF78_RS33240
uniprot id: A0A1D7YIA8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1904616:BFF78 RS38305
gene id: 1904616:BFF78_RS38305
uniprot id: A0A1D7YKP7
names: Similarity
messages: Belongs to the UPF0166 family.

1904616:BFF78 RS05380
gene id: 1904616:BFF78_RS05380
uniprot id: A0A1D7Y4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1904616:BFF78 RS40165
gene id: 1904616:BFF78_RS40165
uniprot id: A0A1D7YLQ6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1904616:BFF78 RS20800
gene id: 1904616:BFF78_RS20800
uniprot id: A0A1D7YC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1904616:BFF78 RS02230
gene id: 1904616:BFF78_RS02230
uniprot id: A0A1D7Y390
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS13750
gene id: 1904616:BFF78_RS13750
uniprot id: A0A1D7YNE3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1904616:BFF78 RS21635
gene id: 1904616:BFF78_RS21635
uniprot id: A0A1D7YCX9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS24365
gene id: 1904616:BFF78_RS24365
uniprot id: A0A1D7YE41
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1904616:BFF78 RS38885
gene id: 1904616:BFF78_RS38885
uniprot id: A0A1D7YKZ7
names: Similarity
messages: Belongs to the YciI family.

1904616:BFF78 RS39210
gene id: 1904616:BFF78_RS39210
uniprot id: A0A1D7YL03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1904616:BFF78 RS27455
gene id: 1904616:BFF78_RS27455
uniprot id: A0A1D7YG31
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1904616:BFF78 RS00195
gene id: 1904616:BFF78_RS00195
uniprot id: A0A1D7Y2C2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1904616:BFF78 RS33690
gene id: 1904616:BFF78_RS33690
uniprot id: A0A1D7YIE3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS38315
gene id: 1904616:BFF78_RS38315
uniprot id: A0A1D7YKK4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS19885
gene id: 1904616:BFF78_RS19885
uniprot id: A0A1D7YBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS09290
gene id: 1904616:BFF78_RS09290
uniprot id: A0A1D7Y6H0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1904616:BFF78 RS22755
gene id: 1904616:BFF78_RS22755
uniprot id: A0A1D7YD11
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1904616:BFF78 RS02465
gene id: 1904616:BFF78_RS02465
uniprot id: A0A1D7YML3
names: Similarity
messages: Belongs to the YciI family.

1904616:BFF78 RS19525
gene id: 1904616:BFF78_RS19525
uniprot id: A0A1D7YBM8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS02795
gene id: 1904616:BFF78_RS02795
uniprot id: A0A1D7Y430
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS27740
gene id: 1904616:BFF78_RS27740
uniprot id: A0A1D7YFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1904616:BFF78 RS13420
gene id: 1904616:BFF78_RS13420
uniprot id: A0A1D7Y8U0
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1904616:BFF78 RS13910
gene id: 1904616:BFF78_RS13910
uniprot id: A0A1D7Y8Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1904616:BFF78 RS12695
gene id: 1904616:BFF78_RS12695
uniprot id: A0A1D7Y858
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS36230
gene id: 1904616:BFF78_RS36230
uniprot id: A0A1D7YJM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS38205
gene id: 1904616:BFF78_RS38205
uniprot id: A0A1D7YKP1
names: Similarity
messages: Belongs to the archease family.

1904616:BFF78 RS05000
gene id: 1904616:BFF78_RS05000
uniprot id: A0A1D7Y4I0
names: Subcellular Location Annotation
messages: cytosol

1904616:BFF78 RS25545
gene id: 1904616:BFF78_RS25545
uniprot id: A0A1D7YEC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1904616:BFF78 RS31705
gene id: 1904616:BFF78_RS31705
uniprot id: A0A1D7YHJ1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1904616:BFF78 RS38550
gene id: 1904616:BFF78_RS38550
uniprot id: A0A1D7YKQ3
names: Similarity
messages: Belongs to the XFP family.

1904616:BFF78 RS24320
gene id: 1904616:BFF78_RS24320
uniprot id: A0A1D7YDR5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1904616:BFF78 RS04785
gene id: 1904616:BFF78_RS04785
uniprot id: A0A1D7Y4E1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1904616:BFF78 RS31510
gene id: 1904616:BFF78_RS31510
uniprot id: A0A1D7YHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1904616:BFF78 RS15230
gene id: 1904616:BFF78_RS15230
uniprot id: A0A1D7Y9D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1904616:BFF78 RS38310
gene id: 1904616:BFF78_RS38310
uniprot id: A0A1D7YKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1904616:BFF78 RS34095
gene id: 1904616:BFF78_RS34095
uniprot id: A0A1D7YIK1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1904616:BFF78 RS34205
gene id: 1904616:BFF78_RS34205
uniprot id: A0A1D7YIM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1904616:BFF78 RS27595
gene id: 1904616:BFF78_RS27595
uniprot id: A0A1D7YFK6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS21360
gene id: 1904616:BFF78_RS21360
uniprot id: A0A1D7YCC4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS17205
gene id: 1904616:BFF78_RS17205
uniprot id: A0A1D7YAS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1904616:BFF78 RS25520
gene id: 1904616:BFF78_RS25520
uniprot id: A0A1D7YEH5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1904616:BFF78 RS39425
gene id: 1904616:BFF78_RS39425
uniprot id: A0A1D7YPY3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1904616:BFF78 RS17410
gene id: 1904616:BFF78_RS17410
uniprot id: A0A1D7YAS4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1904616:BFF78 RS27490
gene id: 1904616:BFF78_RS27490
uniprot id: A0A1D7YPL8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1904616:BFF78 RS21380
gene id: 1904616:BFF78_RS21380
uniprot id: A0A1D7YCI4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1904616:BFF78 RS32705
gene id: 1904616:BFF78_RS32705
uniprot id: A0A1D7YHX0
names: Similarity
messages: Belongs to the peptidase S1 family.

1904616:BFF78 RS32275
gene id: 1904616:BFF78_RS32275
uniprot id: A0A1D7YHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1904616:BFF78 RS10020
gene id: 1904616:BFF78_RS10020
uniprot id: A0A1D7Y6S7
names: Similarity
messages: Belongs to the malate synthase family.

1904616:BFF78 RS25535
gene id: 1904616:BFF78_RS25535
uniprot id: A0A1D7YEC7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1904616:BFF78 RS26150
gene id: 1904616:BFF78_RS26150
uniprot id: A0A1D7YES8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1904616:BFF78 RS26060
gene id: 1904616:BFF78_RS26060
uniprot id: A0A1D7YEL9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS28715
gene id: 1904616:BFF78_RS28715
uniprot id: A0A1D7YFW2
names: Similarity
messages: Belongs to the FGGY kinase family.

1904616:BFF78 RS09370
gene id: 1904616:BFF78_RS09370
uniprot id: A0A1D7Y790
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1904616:BFF78 RS18170
gene id: 1904616:BFF78_RS18170
uniprot id: A0A1D7YAS8
names: Similarity
messages: Belongs to the GSP E family.

1904616:BFF78 RS28330
gene id: 1904616:BFF78_RS28330
uniprot id: A0A1D7YGG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS38010
gene id: 1904616:BFF78_RS38010
uniprot id: A0A1D7YKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1904616:BFF78 RS13475
gene id: 1904616:BFF78_RS13475
uniprot id: A0A1D7Y8V0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS14820
gene id: 1904616:BFF78_RS14820
uniprot id: A0A1D7Y9K1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1904616:BFF78 RS04095
gene id: 1904616:BFF78_RS04095
uniprot id: A0A1D7Y437
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1904616:BFF78 RS21570
gene id: 1904616:BFF78_RS21570
uniprot id: A0A1D7YCH2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS18070
gene id: 1904616:BFF78_RS18070
uniprot id: A0A1D7YAR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS22315
gene id: 1904616:BFF78_RS22315
uniprot id: A0A1D7YCT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1904616:BFF78 RS12975
gene id: 1904616:BFF78_RS12975
uniprot id: A0A1D7Y923
names: Similarity
messages: Belongs to the DprA/Smf family.

1904616:BFF78 RS20085
gene id: 1904616:BFF78_RS20085
uniprot id: A0A1D7YBQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS28485
gene id: 1904616:BFF78_RS28485
uniprot id: A0A1D7YG23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS19920
gene id: 1904616:BFF78_RS19920
uniprot id: A0A1D7YBL8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1904616:BFF78 RS32860
gene id: 1904616:BFF78_RS32860
uniprot id: A0A1D7YI64
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS17560
gene id: 1904616:BFF78_RS17560
uniprot id: A0A1D7YAP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1904616:BFF78 RS02640
gene id: 1904616:BFF78_RS02640
uniprot id: A0A1D7Y3I6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS13175
gene id: 1904616:BFF78_RS13175
uniprot id: A0A1D7Y957
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1904616:BFF78 RS32050
gene id: 1904616:BFF78_RS32050
uniprot id: A0A1D7YHK2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1904616:BFF78 RS24590
gene id: 1904616:BFF78_RS24590
uniprot id: A0A1D7YE95
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1904616:BFF78 RS11885
gene id: 1904616:BFF78_RS11885
uniprot id: A0A1D7Y863
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS27845
gene id: 1904616:BFF78_RS27845
uniprot id: A0A1D7YFG0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1904616:BFF78 RS15935
gene id: 1904616:BFF78_RS15935
uniprot id: A0A1D7Y9V8
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS11720
gene id: 1904616:BFF78_RS11720
uniprot id: A0A1D7Y8E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1904616:BFF78 RS15825
gene id: 1904616:BFF78_RS15825
uniprot id: A0A1D7YNF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1904616:BFF78 RS19835
gene id: 1904616:BFF78_RS19835
uniprot id: A0A1D7YBS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1904616:BFF78 RS33295
gene id: 1904616:BFF78_RS33295
uniprot id: A0A1D7YIB7
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1904616:BFF78 RS06695
gene id: 1904616:BFF78_RS06695
uniprot id: A0A1D7Y576
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS06040
gene id: 1904616:BFF78_RS06040
uniprot id: A0A1D7Y555
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21560
gene id: 1904616:BFF78_RS21560
uniprot id: A0A1D7YCH0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS31820
gene id: 1904616:BFF78_RS31820
uniprot id: A0A1D7YHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS04255
gene id: 1904616:BFF78_RS04255
uniprot id: A0A1D7Y456
names: Similarity
messages: Belongs to the pirin family.

1904616:BFF78 RS18275
gene id: 1904616:BFF78_RS18275
uniprot id: A0A1D7YAU8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1904616:BFF78 RS30735
gene id: 1904616:BFF78_RS30735
uniprot id: A0A1D7YGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1904616:BFF78 RS07500
gene id: 1904616:BFF78_RS07500
uniprot id: A0A1D7YN13
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS19100
gene id: 1904616:BFF78_RS19100
uniprot id: A0A1D7YBQ0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS23400
gene id: 1904616:BFF78_RS23400
uniprot id: A0A1D7YDI8
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS39105
gene id: 1904616:BFF78_RS39105
uniprot id: A0A1D7YL53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1904616:BFF78 RS10110
gene id: 1904616:BFF78_RS10110
uniprot id: A0A1D7Y6Y5
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

1904616:BFF78 RS35490
gene id: 1904616:BFF78_RS35490
uniprot id: A0A1D7YJ95
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1904616:BFF78 RS26455
gene id: 1904616:BFF78_RS26455
uniprot id: A0A1D7YF28
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1904616:BFF78 RS32510
gene id: 1904616:BFF78_RS32510
uniprot id: A0A1D7YHS5
names: Similarity
messages: Belongs to the TlyA family.

1904616:BFF78 RS39865
gene id: 1904616:BFF78_RS39865
uniprot id: A0A1D7YLH1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1904616:BFF78 RS34180
gene id: 1904616:BFF78_RS34180
uniprot id: A0A1D7YIT5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS15420
gene id: 1904616:BFF78_RS15420
uniprot id: A0A1D7Y9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS17155
gene id: 1904616:BFF78_RS17155
uniprot id: A0A1D7YAR1
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1904616:BFF78 RS41100
gene id: 1904616:BFF78_RS41100
uniprot id: A0A1D7YM33
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS35960
gene id: 1904616:BFF78_RS35960
uniprot id: A0A1D7YPR5
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

1904616:BFF78 RS20920
gene id: 1904616:BFF78_RS20920
uniprot id: A0A1D7YCY5
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1904616:BFF78 RS06095
gene id: 1904616:BFF78_RS06095
uniprot id: A0A1D7Y560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS23755
gene id: 1904616:BFF78_RS23755
uniprot id: A0A1D7YDH7
names: Similarity
messages: Belongs to the UPF0309 family.

1904616:BFF78 RS35480
gene id: 1904616:BFF78_RS35480
uniprot id: A0A1D7YJ99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1904616:BFF78 RS40020
gene id: 1904616:BFF78_RS40020
uniprot id: A0A1D7YLJ5
names: Similarity
messages: Belongs to the peptidase A31 family.

1904616:BFF78 RS39280
gene id: 1904616:BFF78_RS39280
uniprot id: A0A1D7YL74
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS15560
gene id: 1904616:BFF78_RS15560
uniprot id: A0A1D7Y9J6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1904616:BFF78 RS14190
gene id: 1904616:BFF78_RS14190
uniprot id: A0A1D7Y8V2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1904616:BFF78 RS27505
gene id: 1904616:BFF78_RS27505
uniprot id: A0A1D7YFB3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1904616:BFF78 RS12775
gene id: 1904616:BFF78_RS12775
uniprot id: A0A1D7Y851
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS03130
gene id: 1904616:BFF78_RS03130
uniprot id: A0A1D7Y416
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1904616:BFF78 RS20845
gene id: 1904616:BFF78_RS20845
uniprot id: A0A1D7YCF9
names: Similarity
messages: Belongs to the LOR family.

1904616:BFF78 RS28345
gene id: 1904616:BFF78_RS28345
uniprot id: A0A1D7YFV9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24470
gene id: 1904616:BFF78_RS24470
uniprot id: A0A1D7YNY3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1904616:BFF78 RS34470
gene id: 1904616:BFF78_RS34470
uniprot id: A0A1D7YIY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1904616:BFF78 RS25605
gene id: 1904616:BFF78_RS25605
uniprot id: A0A1D7YEN4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1904616:BFF78 RS31360
gene id: 1904616:BFF78_RS31360
uniprot id: A0A1D7YHD1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24655
gene id: 1904616:BFF78_RS24655
uniprot id: A0A1D7YE45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1904616:BFF78 RS40430
gene id: 1904616:BFF78_RS40430
uniprot id: A0A1D7YLR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1904616:BFF78 RS18105
gene id: 1904616:BFF78_RS18105
uniprot id: A0A1D7YAV9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1904616:BFF78 RS14680
gene id: 1904616:BFF78_RS14680
uniprot id: A0A1D7Y991
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS14885
gene id: 1904616:BFF78_RS14885
uniprot id: A0A1D7Y981
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1904616:BFF78 RS17990
gene id: 1904616:BFF78_RS17990
uniprot id: A0A1D7YAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS24480
gene id: 1904616:BFF78_RS24480
uniprot id: A0A1D7YE13
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1904616:BFF78 RS04925
gene id: 1904616:BFF78_RS04925
uniprot id: A0A1D7Y4X1
names: Similarity
messages: Belongs to the FPG family.

1904616:BFF78 RS40200
gene id: 1904616:BFF78_RS40200
uniprot id: A0A1D7YLI0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1904616:BFF78 RS41320
gene id: 1904616:BFF78_RS41320
uniprot id: A0A1D7YM64
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1904616:BFF78 RS10705
gene id: 1904616:BFF78_RS10705
uniprot id: A0A1D7Y7L0
names: Similarity
messages: Belongs to the CTP synthase family.

1904616:BFF78 RS24200
gene id: 1904616:BFF78_RS24200
uniprot id: A0A1D7YE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1904616:BFF78 RS38525
gene id: 1904616:BFF78_RS38525
uniprot id: A0A1D7YLB7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1904616:BFF78 RS22345
gene id: 1904616:BFF78_RS22345
uniprot id: A0A1D7YD06
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS30910
gene id: 1904616:BFF78_RS30910
uniprot id: A0A1D7YGZ1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1904616:BFF78 RS41185
gene id: 1904616:BFF78_RS41185
uniprot id: A0A1D7YM20
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21245
gene id: 1904616:BFF78_RS21245
uniprot id: A0A1D7YCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1904616:BFF78 RS36725
gene id: 1904616:BFF78_RS36725
uniprot id: A0A1D7YK19
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS15750
gene id: 1904616:BFF78_RS15750
uniprot id: A0A1D7YAG7
names: Similarity
messages: Belongs to the NodU/CmcH family.

1904616:BFF78 RS11045
gene id: 1904616:BFF78_RS11045
uniprot id: A0A1D7Y828
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1904616:BFF78 RS28585
gene id: 1904616:BFF78_RS28585
uniprot id: A0A1D7YG43
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS14290
gene id: 1904616:BFF78_RS14290
uniprot id: A0A1D7Y8X0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS15800
gene id: 1904616:BFF78_RS15800
uniprot id: A0A1D7YAH7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS20365
gene id: 1904616:BFF78_RS20365
uniprot id: A0A1D7YBU7
names: Similarity
messages: Belongs to the DNA photolyase family.

1904616:BFF78 RS16845
gene id: 1904616:BFF78_RS16845
uniprot id: A0A1D7YAZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS17865
gene id: 1904616:BFF78_RS17865
uniprot id: A0A1D7YAR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1904616:BFF78 RS32565
gene id: 1904616:BFF78_RS32565
uniprot id: A0A1D7YHU7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1904616:BFF78 RS39115
gene id: 1904616:BFF78_RS39115
uniprot id: A0A1D7YL86
names: Similarity
messages: Belongs to the melC1 family.

1904616:BFF78 RS18160
gene id: 1904616:BFF78_RS18160
uniprot id: A0A1D7YAX0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS31395
gene id: 1904616:BFF78_RS31395
uniprot id: A0A1D7YHD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1904616:BFF78 RS19075
gene id: 1904616:BFF78_RS19075
uniprot id: A0A1D7YBM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS37195
gene id: 1904616:BFF78_RS37195
uniprot id: A0A1D7YKR7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS10675
gene id: 1904616:BFF78_RS10675
uniprot id: A0A1D7Y7G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1904616:BFF78 RS31660
gene id: 1904616:BFF78_RS31660
uniprot id: A0A1D7YHI1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34975
gene id: 1904616:BFF78_RS34975
uniprot id: A0A1D7YJ12
names: Similarity
messages: Belongs to the 3-hydroxybenzoate 6-hydroxylase family.

1904616:BFF78 RS29625
gene id: 1904616:BFF78_RS29625
uniprot id: A0A1D7YH34
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1904616:BFF78 RS28080
gene id: 1904616:BFF78_RS28080
uniprot id: A0A1D7YFV7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1904616:BFF78 RS37280
gene id: 1904616:BFF78_RS37280
uniprot id: A0A1D7YK82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1904616:BFF78 RS17565
gene id: 1904616:BFF78_RS17565
uniprot id: A0A1D7YAH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1904616:BFF78 RS32885
gene id: 1904616:BFF78_RS32885
uniprot id: A0A1D7YI06
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS13130
gene id: 1904616:BFF78_RS13130
uniprot id: A0A1D7Y8S3
names: Similarity
messages: Belongs to the acylphosphatase family.

1904616:BFF78 RS01815
gene id: 1904616:BFF78_RS01815
uniprot id: A0A1D7YJM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1904616:BFF78 RS30860
gene id: 1904616:BFF78_RS30860
uniprot id: A0A1D7YH56
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS13035
gene id: 1904616:BFF78_RS13035
uniprot id: A0A1D7Y8G7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1904616:BFF78 RS33275
gene id: 1904616:BFF78_RS33275
uniprot id: A0A1D7YI60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1904616:BFF78 RS07395
gene id: 1904616:BFF78_RS07395
uniprot id: A0A1D7Y5V7
names: Similarity
messages: Belongs to the glutamate synthase family.

1904616:BFF78 RS11550
gene id: 1904616:BFF78_RS11550
uniprot id: A0A1D7Y8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1904616:BFF78 RS27425
gene id: 1904616:BFF78_RS27425
uniprot id: A0A1D7YFJ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1904616:BFF78 RS33555
gene id: 1904616:BFF78_RS33555
uniprot id: A0A1D7YIH8
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS28745
gene id: 1904616:BFF78_RS28745
uniprot id: A0A1D7YFV6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1904616:BFF78 RS11040
gene id: 1904616:BFF78_RS11040
uniprot id: A0A1D7Y7B1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34825
gene id: 1904616:BFF78_RS34825
uniprot id: A0A1D7YJ32
names: Similarity
messages: Belongs to the universal stress protein A family.

1904616:BFF78 RS18120
gene id: 1904616:BFF78_RS18120
uniprot id: A0A1D7YB40
names: Similarity
messages: Belongs to the peptidase A24 family.

1904616:BFF78 RS36450
gene id: 1904616:BFF78_RS36450
uniprot id: A0A1D7YJW4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1904616:BFF78 RS10665
gene id: 1904616:BFF78_RS10665
uniprot id: A0A1D7Y783
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

1904616:BFF78 RS38920
gene id: 1904616:BFF78_RS38920
uniprot id: A0A1D7YL16
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS09220
gene id: 1904616:BFF78_RS09220
uniprot id: A0A1D7Y6R0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1904616:BFF78 RS26720
gene id: 1904616:BFF78_RS26720
uniprot id: A0A1D7YF76
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1904616:BFF78 RS17940
gene id: 1904616:BFF78_RS17940
uniprot id: A0A1D7YAV6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1904616:BFF78 RS38250
gene id: 1904616:BFF78_RS38250
uniprot id: A0A1D7YKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1904616:BFF78 RS06395
gene id: 1904616:BFF78_RS06395
uniprot id: A0A1D7Y5A6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS22915
gene id: 1904616:BFF78_RS22915
uniprot id: A0A1D7YD40
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS06855
gene id: 1904616:BFF78_RS06855
uniprot id: A0A1D7Y5B0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1904616:BFF78 RS09780
gene id: 1904616:BFF78_RS09780
uniprot id: A0A1D7Y752
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1904616:BFF78 RS15910
gene id: 1904616:BFF78_RS15910
uniprot id: A0A1D7Y9Q1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS17625
gene id: 1904616:BFF78_RS17625
uniprot id: A0A1D7YAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1904616:BFF78 RS13275
gene id: 1904616:BFF78_RS13275
uniprot id: A0A1D7Y8E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1904616:BFF78 RS03800
gene id: 1904616:BFF78_RS03800
uniprot id: A0A1D7Y3Y3
names: Similarity
messages: Belongs to the AHA1 family.

1904616:BFF78 RS30935
gene id: 1904616:BFF78_RS30935
uniprot id: A0A1D7YH08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1904616:BFF78 RS14255
gene id: 1904616:BFF78_RS14255
uniprot id: A0A1D7Y993
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1904616:BFF78 RS17390
gene id: 1904616:BFF78_RS17390
uniprot id: A0A1D7YAU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1904616:BFF78 RS05130
gene id: 1904616:BFF78_RS05130
uniprot id: A0A1D7Y4K9
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1904616:BFF78 RS31535
gene id: 1904616:BFF78_RS31535
uniprot id: A0A1D7YHZ3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1904616:BFF78 RS19175
gene id: 1904616:BFF78_RS19175
uniprot id: A0A1D7YBA1
names: Similarity
messages: Belongs to the UPF0145 family.

1904616:BFF78 RS01550
gene id: 1904616:BFF78_RS01550
uniprot id: A0A1D7Y2Y7
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1904616:BFF78 RS34070
gene id: 1904616:BFF78_RS34070
uniprot id: A0A1D7YPG7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1904616:BFF78 RS11555
gene id: 1904616:BFF78_RS11555
uniprot id: A0A1D7Y805
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1904616:BFF78 RS07460
gene id: 1904616:BFF78_RS07460
uniprot id: A0A1D7Y5N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1904616:BFF78 RS15930
gene id: 1904616:BFF78_RS15930
uniprot id: A0A1D7YND0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS12760
gene id: 1904616:BFF78_RS12760
uniprot id: A0A1D7Y8H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS01860
gene id: 1904616:BFF78_RS01860
uniprot id: A0A1D7Y363
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS28045
gene id: 1904616:BFF78_RS28045
uniprot id: A0A1D7YGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1904616:BFF78 RS22310
gene id: 1904616:BFF78_RS22310
uniprot id: A0A1D7YD28
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1904616:BFF78 RS18770
gene id: 1904616:BFF78_RS18770
uniprot id: A0A1D7YB29
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS05010
gene id: 1904616:BFF78_RS05010
uniprot id: A0A1D7Y4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS18355
gene id: 1904616:BFF78_RS18355
uniprot id: A0A1D7YBB3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1904616:BFF78 RS13210
gene id: 1904616:BFF78_RS13210
uniprot id: A0A1D7Y8R4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1904616:BFF78 RS38900
gene id: 1904616:BFF78_RS38900
uniprot id: A0A1D7YKV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS11825
gene id: 1904616:BFF78_RS11825
uniprot id: A0A1D7Y8G9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS07300
gene id: 1904616:BFF78_RS07300
uniprot id: A0A1D7Y5M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1904616:BFF78 RS06445
gene id: 1904616:BFF78_RS06445
uniprot id: A0A1D7Y5A7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1904616:BFF78 RS27725
gene id: 1904616:BFF78_RS27725
uniprot id: A0A1D7YFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS13040
gene id: 1904616:BFF78_RS13040
uniprot id: A0A1D7Y8F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1904616:BFF78 RS14325
gene id: 1904616:BFF78_RS14325
uniprot id: A0A1D7Y9B9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1904616:BFF78 RS10525
gene id: 1904616:BFF78_RS10525
uniprot id: A0A1D7Y7D6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1904616:BFF78 RS13835
gene id: 1904616:BFF78_RS13835
uniprot id: A0A1D7Y8U6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS27155
gene id: 1904616:BFF78_RS27155
uniprot id: A0A1D7YFD6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS37900
gene id: 1904616:BFF78_RS37900
uniprot id: A0A1D7YKJ8
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1904616:BFF78 RS33290
gene id: 1904616:BFF78_RS33290
uniprot id: A0A1D7YPF0
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1904616:BFF78 RS02960
gene id: 1904616:BFF78_RS02960
uniprot id: A0A1D7Y466
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS40160
gene id: 1904616:BFF78_RS40160
uniprot id: A0A1D7YLH9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS39740
gene id: 1904616:BFF78_RS39740
uniprot id: A0A1D7YLE8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS08790
gene id: 1904616:BFF78_RS08790
uniprot id: A0A1D7YN86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS12635
gene id: 1904616:BFF78_RS12635
uniprot id: A0A1D7Y894
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1904616:BFF78 RS07585
gene id: 1904616:BFF78_RS07585
uniprot id: A0A1D7Y629
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS40710
gene id: 1904616:BFF78_RS40710
uniprot id: A0A1D7YLS2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS17365
gene id: 1904616:BFF78_RS17365
uniprot id: A0A1D7YAD9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1904616:BFF78 RS35270
gene id: 1904616:BFF78_RS35270
uniprot id: A0A1D7YJ51
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS16330
gene id: 1904616:BFF78_RS16330
uniprot id: A0A1D7YA96
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS18280
gene id: 1904616:BFF78_RS18280
uniprot id: A0A1D7YB69
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS33365
gene id: 1904616:BFF78_RS33365
uniprot id: A0A1D7YID9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1904616:BFF78 RS31440
gene id: 1904616:BFF78_RS31440
uniprot id: A0A1D7YHG4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS12620
gene id: 1904616:BFF78_RS12620
uniprot id: A0A1D7Y814
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1904616:BFF78 RS13215
gene id: 1904616:BFF78_RS13215
uniprot id: A0A1D7Y8F1
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1904616:BFF78 RS22700
gene id: 1904616:BFF78_RS22700
uniprot id: A0A1D7YD83
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS29915
gene id: 1904616:BFF78_RS29915
uniprot id: A0A1D7YGH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1904616:BFF78 RS12030
gene id: 1904616:BFF78_RS12030
uniprot id: A0A1D7YN77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1904616:BFF78 RS20005
gene id: 1904616:BFF78_RS20005
uniprot id: A0A1D7YBV5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS17795
gene id: 1904616:BFF78_RS17795
uniprot id: A0A1D7YNN6
names: Similarity
messages: Belongs to the UPF0234 family.

1904616:BFF78 RS13480
gene id: 1904616:BFF78_RS13480
uniprot id: A0A1D7Y8H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS24840
gene id: 1904616:BFF78_RS24840
uniprot id: A0A1D7YP23
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS01420
gene id: 1904616:BFF78_RS01420
uniprot id: A0A1D7Y2Y1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1904616:BFF78 RS27805
gene id: 1904616:BFF78_RS27805
uniprot id: A0A1D7YG83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1904616:BFF78 RS31435
gene id: 1904616:BFF78_RS31435
uniprot id: A0A1D7YHE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1904616:BFF78 RS26955
gene id: 1904616:BFF78_RS26955
uniprot id: A0A1D7YF29
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1904616:BFF78 RS15310
gene id: 1904616:BFF78_RS15310
uniprot id: A0A1D7Y9J7
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS17015
gene id: 1904616:BFF78_RS17015
uniprot id: A0A1D7YAN3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1904616:BFF78 RS16955
gene id: 1904616:BFF78_RS16955
uniprot id: A0A1D7YAM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1904616:BFF78 RS17335
gene id: 1904616:BFF78_RS17335
uniprot id: A0A1D7YAU0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1904616:BFF78 RS24015
gene id: 1904616:BFF78_RS24015
uniprot id: A0A1D7YP54
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS26570
gene id: 1904616:BFF78_RS26570
uniprot id: A0A1D7YEU7
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1904616:BFF78 RS21510
gene id: 1904616:BFF78_RS21510
uniprot id: A0A1D7YCG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1904616:BFF78 RS29165
gene id: 1904616:BFF78_RS29165
uniprot id: A0A1D7YG27
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS40040
gene id: 1904616:BFF78_RS40040
uniprot id: A0A1D7YLN6
names: Similarity
messages: Belongs to the HypD family.

1904616:BFF78 RS27280
gene id: 1904616:BFF78_RS27280
uniprot id: A0A1D7YFH3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS32210
gene id: 1904616:BFF78_RS32210
uniprot id: A0A1D7YHS9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS13160
gene id: 1904616:BFF78_RS13160
uniprot id: A0A1D7Y8Q2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1904616:BFF78 RS21365
gene id: 1904616:BFF78_RS21365
uniprot id: A0A1D7YD68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1904616:BFF78 RS24080
gene id: 1904616:BFF78_RS24080
uniprot id: A0A1D7YEG1
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

1904616:BFF78 RS15585
gene id: 1904616:BFF78_RS15585
uniprot id: A0A1D7YA04
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41870
gene id: 1904616:BFF78_RS41870
uniprot id: A0A1D7YMB4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS29695
gene id: 1904616:BFF78_RS29695
uniprot id: A0A1D7YGI6
names: Similarity
messages: Belongs to the thioesterase family.

1904616:BFF78 RS13025
gene id: 1904616:BFF78_RS13025
uniprot id: A0A1D7Y933
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1904616:BFF78 RS02580
gene id: 1904616:BFF78_RS02580
uniprot id: A0A1D7Y3F4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS05545
gene id: 1904616:BFF78_RS05545
uniprot id: A0A1D7Y4Q6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS47530
gene id: 1904616:BFF78_RS47530
uniprot id: A0A1D7YMH4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS32655
gene id: 1904616:BFF78_RS32655
uniprot id: A0A1D7YHW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1904616:BFF78 RS17050
gene id: 1904616:BFF78_RS17050
uniprot id: A0A1D7YAD3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21600
gene id: 1904616:BFF78_RS21600
uniprot id: A0A1D7YCH8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS07020
gene id: 1904616:BFF78_RS07020
uniprot id: A0A1D7Y5P0
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1904616:BFF78 RS07335
gene id: 1904616:BFF78_RS07335
uniprot id: A0A1D7Y5J4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1904616:BFF78 RS20050
gene id: 1904616:BFF78_RS20050
uniprot id: A0A1D7YBP5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS28695
gene id: 1904616:BFF78_RS28695
uniprot id: A0A1D7YG19
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1904616:BFF78 RS24560
gene id: 1904616:BFF78_RS24560
uniprot id: A0A1D7YE70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1904616:BFF78 RS11660
gene id: 1904616:BFF78_RS11660
uniprot id: A0A1D7Y7T3
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1904616:BFF78 RS09260
gene id: 1904616:BFF78_RS09260
uniprot id: A0A1D7Y6L7
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

1904616:BFF78 RS17380
gene id: 1904616:BFF78_RS17380
uniprot id: A0A1D7YAE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1904616:BFF78 RS38970
gene id: 1904616:BFF78_RS38970
uniprot id: A0A1D7YL19
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS13070
gene id: 1904616:BFF78_RS13070
uniprot id: A0A1D7Y899
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1904616:BFF78 RS24050
gene id: 1904616:BFF78_RS24050
uniprot id: A0A1D7YDW2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1904616:BFF78 RS08755
gene id: 1904616:BFF78_RS08755
uniprot id: A0A1D7Y6G6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1904616:BFF78 RS26215
gene id: 1904616:BFF78_RS26215
uniprot id: A0A1D7YEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS25010
gene id: 1904616:BFF78_RS25010
uniprot id: A0A1D7YE93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1904616:BFF78 RS14825
gene id: 1904616:BFF78_RS14825
uniprot id: A0A1D7Y974
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1904616:BFF78 RS13785
gene id: 1904616:BFF78_RS13785
uniprot id: A0A1D7Y8N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1904616:BFF78 RS11700
gene id: 1904616:BFF78_RS11700
uniprot id: A0A1D7Y7P1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS40375
gene id: 1904616:BFF78_RS40375
uniprot id: A0A1D7YM78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1904616:BFF78 RS13065
gene id: 1904616:BFF78_RS13065
uniprot id: A0A1D7Y8A3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1904616:BFF78 RS26305
gene id: 1904616:BFF78_RS26305
uniprot id: A0A1D7YEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS33115
gene id: 1904616:BFF78_RS33115
uniprot id: A0A1D7YI45
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

1904616:BFF78 RS27605
gene id: 1904616:BFF78_RS27605
uniprot id: A0A1D7YFM4
names: Similarity
messages: Belongs to the peptidase M1 family.

1904616:BFF78 RS04155
gene id: 1904616:BFF78_RS04155
uniprot id: A0A1D7Y467
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS05555
gene id: 1904616:BFF78_RS05555
uniprot id: A0A1D7Y4S1
names: Similarity
messages: Belongs to the peptidase S33 family.

1904616:BFF78 RS34475
gene id: 1904616:BFF78_RS34475
uniprot id: A0A1D7YIX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS30915
gene id: 1904616:BFF78_RS30915
uniprot id: A0A1D7YHQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1904616:BFF78 RS35965
gene id: 1904616:BFF78_RS35965
uniprot id: A0A1D7YJH5
names: Similarity
messages: Belongs to the Fur family.

1904616:BFF78 RS12450
gene id: 1904616:BFF78_RS12450
uniprot id: A0A1D7Y8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1904616:BFF78 RS01105
gene id: 1904616:BFF78_RS01105
uniprot id: A0A1D7Y2C2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1904616:BFF78 RS33560
gene id: 1904616:BFF78_RS33560
uniprot id: A0A1D7YIC0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1904616:BFF78 RS40635
gene id: 1904616:BFF78_RS40635
uniprot id: A0A1D7YLZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1904616:BFF78 RS05285
gene id: 1904616:BFF78_RS05285
uniprot id: A0A1D7Y4S3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS41325
gene id: 1904616:BFF78_RS41325
uniprot id: A0A1D7YM18
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS29450
gene id: 1904616:BFF78_RS29450
uniprot id: A0A1D7YGG5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS35930
gene id: 1904616:BFF78_RS35930
uniprot id: A0A1D7YJM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1904616:BFF78 RS34290
gene id: 1904616:BFF78_RS34290
uniprot id: A0A1D7YIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS17180
gene id: 1904616:BFF78_RS17180
uniprot id: A0A1D7YAA8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS30590
gene id: 1904616:BFF78_RS30590
uniprot id: A0A1D7YGV0
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1904616:BFF78 RS03865
gene id: 1904616:BFF78_RS03865
uniprot id: A0A1D7Y400
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1904616:BFF78 RS04460
gene id: 1904616:BFF78_RS04460
uniprot id: A0A1D7Y4B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1904616:BFF78 RS05790
gene id: 1904616:BFF78_RS05790
uniprot id: A0A1D7Y4V9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS32330
gene id: 1904616:BFF78_RS32330
uniprot id: A0A1D7YHV1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1904616:BFF78 RS12520
gene id: 1904616:BFF78_RS12520
uniprot id: A0A1D7Y8D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1904616:BFF78 RS19460
gene id: 1904616:BFF78_RS19460
uniprot id: A0A1D7YBI4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1904616:BFF78 RS31540
gene id: 1904616:BFF78_RS31540
uniprot id: A0A1D7YHG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS17590
gene id: 1904616:BFF78_RS17590
uniprot id: A0A1D7YAH9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1904616:BFF78 RS24225
gene id: 1904616:BFF78_RS24225
uniprot id: A0A1D7YDR6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS23300
gene id: 1904616:BFF78_RS23300
uniprot id: A0A1D7YDH6
names: Similarity
messages: Belongs to the peptidase M1 family.

1904616:BFF78 RS12660
gene id: 1904616:BFF78_RS12660
uniprot id: A0A1D7Y8F2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS24855
gene id: 1904616:BFF78_RS24855
uniprot id: A0A1D7YE15
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1904616:BFF78 RS11915
gene id: 1904616:BFF78_RS11915
uniprot id: A0A1D7Y7S9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS32625
gene id: 1904616:BFF78_RS32625
uniprot id: A0A1D7YHV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1904616:BFF78 RS26225
gene id: 1904616:BFF78_RS26225
uniprot id: A0A1D7YEP9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1904616:BFF78 RS40170
gene id: 1904616:BFF78_RS40170
uniprot id: A0A1D7YQ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1904616:BFF78 RS23685
gene id: 1904616:BFF78_RS23685
uniprot id: A0A1D7YDT1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1904616:BFF78 RS19865
gene id: 1904616:BFF78_RS19865
uniprot id: A0A1D7YBL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1904616:BFF78 RS20115
gene id: 1904616:BFF78_RS20115
uniprot id: A0A1D7YC58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1904616:BFF78 RS34055
gene id: 1904616:BFF78_RS34055
uniprot id: A0A1D7YIJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS38360
gene id: 1904616:BFF78_RS38360
uniprot id: A0A1D7YKT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS17035
gene id: 1904616:BFF78_RS17035
uniprot id: A0A1D7YNN4
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS34535
gene id: 1904616:BFF78_RS34535
uniprot id: A0A1D7YJ08
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS30535
gene id: 1904616:BFF78_RS30535
uniprot id: A0A1D7YGZ8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS33995
gene id: 1904616:BFF78_RS33995
uniprot id: A0A1D7YIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1904616:BFF78 RS00850
gene id: 1904616:BFF78_RS00850
uniprot id: A0A1D7Y2L0
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1904616:BFF78 RS38980
gene id: 1904616:BFF78_RS38980
uniprot id: A0A1D7YKW4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS33540
gene id: 1904616:BFF78_RS33540
uniprot id: A0A1D7YIH6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1904616:BFF78 RS30745
gene id: 1904616:BFF78_RS30745
uniprot id: A0A1D7YH38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1904616:BFF78 RS34520
gene id: 1904616:BFF78_RS34520
uniprot id: A0A1D7YJJ2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS02740
gene id: 1904616:BFF78_RS02740
uniprot id: A0A1D7Y423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS20070
gene id: 1904616:BFF78_RS20070
uniprot id: A0A1D7YBW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS17480
gene id: 1904616:BFF78_RS17480
uniprot id: A0A1D7YAG5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1904616:BFF78 RS18035
gene id: 1904616:BFF78_RS18035
uniprot id: A0A1D7YB60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS21815
gene id: 1904616:BFF78_RS21815
uniprot id: A0A1D7YP00
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

1904616:BFF78 RS16710
gene id: 1904616:BFF78_RS16710
uniprot id: A0A1D7YAI1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1904616:BFF78 RS05100
gene id: 1904616:BFF78_RS05100
uniprot id: A0A1D7Y4J4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1904616:BFF78 RS12860
gene id: 1904616:BFF78_RS12860
uniprot id: A0A1D7Y8M2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS33670
gene id: 1904616:BFF78_RS33670
uniprot id: A0A1D7YPI3
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

1904616:BFF78 RS29100
gene id: 1904616:BFF78_RS29100
uniprot id: A0A1D7YG29
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1904616:BFF78 RS19190
gene id: 1904616:BFF78_RS19190
uniprot id: A0A1D7YBP3
names: Similarity
messages: Belongs to the group II decarboxylase family.

1904616:BFF78 RS14260
gene id: 1904616:BFF78_RS14260
uniprot id: A0A1D7Y8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1904616:BFF78 RS30740
gene id: 1904616:BFF78_RS30740
uniprot id: A0A1D7YHN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS11585
gene id: 1904616:BFF78_RS11585
uniprot id: A0A1D7Y7X8
names: Similarity
messages: Belongs to the peptidase S11 family.

1904616:BFF78 RS02990
gene id: 1904616:BFF78_RS02990
uniprot id: A0A1D7Y3L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1904616:BFF78 RS17385
gene id: 1904616:BFF78_RS17385
uniprot id: A0A1D7YB84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1904616:BFF78 RS13235
gene id: 1904616:BFF78_RS13235
uniprot id: A0A1D7Y968
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1904616:BFF78 RS34780
gene id: 1904616:BFF78_RS34780
uniprot id: A0A1D7YIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1904616:BFF78 RS30785
gene id: 1904616:BFF78_RS30785
uniprot id: A0A1D7YGX4
names: Similarity
messages: Belongs to the YggT family.

1904616:BFF78 RS21440
gene id: 1904616:BFF78_RS21440
uniprot id: A0A1D7YCF2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1904616:BFF78 RS40045
gene id: 1904616:BFF78_RS40045
uniprot id: A0A1D7YLH7
names: Similarity
messages: Belongs to the HypE family.

1904616:BFF78 RS37130
gene id: 1904616:BFF78_RS37130
uniprot id: A0A1D7YKQ8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1904616:BFF78 RS33630
gene id: 1904616:BFF78_RS33630
uniprot id: A0A1D7YIH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1904616:BFF78 RS12950
gene id: 1904616:BFF78_RS12950
uniprot id: A0A1D7Y8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1904616:BFF78 RS10265
gene id: 1904616:BFF78_RS10265
uniprot id: A0A1D7Y6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1904616:BFF78 RS10630
gene id: 1904616:BFF78_RS10630
uniprot id: A0A1D7Y759
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

1904616:BFF78 RS02575
gene id: 1904616:BFF78_RS02575
uniprot id: A0A1D7Y3E9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS31255
gene id: 1904616:BFF78_RS31255
uniprot id: A0A1D7YH48
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1904616:BFF78 RS20265
gene id: 1904616:BFF78_RS20265
uniprot id: A0A1D7YBV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1904616:BFF78 RS15285
gene id: 1904616:BFF78_RS15285
uniprot id: A0A1D7Y9F4
names: Similarity
messages: Belongs to the LOG family.

1904616:BFF78 RS06060
gene id: 1904616:BFF78_RS06060
uniprot id: A0A1D7Y5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS26645
gene id: 1904616:BFF78_RS26645
uniprot id: A0A1D7YF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1904616:BFF78 RS34195
gene id: 1904616:BFF78_RS34195
uniprot id: A0A1D7YIM2
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

1904616:BFF78 RS06595
gene id: 1904616:BFF78_RS06595
uniprot id: A0A1D7Y595
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1904616:BFF78 RS14330
gene id: 1904616:BFF78_RS14330
uniprot id: A0A1D7Y936
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS28020
gene id: 1904616:BFF78_RS28020
uniprot id: A0A1D7YFJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1904616:BFF78 RS15445
gene id: 1904616:BFF78_RS15445
uniprot id: A0A1D7Y9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS03575
gene id: 1904616:BFF78_RS03575
uniprot id: A0A1D7Y4G9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS25450
gene id: 1904616:BFF78_RS25450
uniprot id: A0A1D7YEG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1904616:BFF78 RS32065
gene id: 1904616:BFF78_RS32065
uniprot id: A0A1D7YHJ6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1904616:BFF78 RS40690
gene id: 1904616:BFF78_RS40690
uniprot id: A0A1D7YLS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS27840
gene id: 1904616:BFF78_RS27840
uniprot id: A0A1D7YFR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1904616:BFF78 RS17285
gene id: 1904616:BFF78_RS17285
uniprot id: A0A1D7YAJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1904616:BFF78 RS24995
gene id: 1904616:BFF78_RS24995
uniprot id: A0A1D7YEV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS25270
gene id: 1904616:BFF78_RS25270
uniprot id: A0A1D7YE89
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1904616:BFF78 RS32715
gene id: 1904616:BFF78_RS32715
uniprot id: A0A1D7YPG5
names: Similarity
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

1904616:BFF78 RS23810
gene id: 1904616:BFF78_RS23810
uniprot id: A0A1D7YDU8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1904616:BFF78 RS34390
gene id: 1904616:BFF78_RS34390
uniprot id: A0A1D7YIW1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1904616:BFF78 RS26920
gene id: 1904616:BFF78_RS26920
uniprot id: A0A1D7YF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1904616:BFF78 RS39820
gene id: 1904616:BFF78_RS39820
uniprot id: A0A1D7YPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1904616:BFF78 RS30135
gene id: 1904616:BFF78_RS30135
uniprot id: A0A1D7YGT0
names: Similarity
messages: Belongs to the ArsC family.

1904616:BFF78 RS13635
gene id: 1904616:BFF78_RS13635
uniprot id: A0A1D7Y8X6
names: Similarity
messages: Belongs to the LOG family.

1904616:BFF78 RS06560
gene id: 1904616:BFF78_RS06560
uniprot id: A0A1D7Y5A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1904616:BFF78 RS22305
gene id: 1904616:BFF78_RS22305
uniprot id: A0A1D7YCT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1904616:BFF78 RS34355
gene id: 1904616:BFF78_RS34355
uniprot id: A0A1D7YPI9
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1904616:BFF78 RS04025
gene id: 1904616:BFF78_RS04025
uniprot id: A0A1D7Y415
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS40270
gene id: 1904616:BFF78_RS40270
uniprot id: A0A1D7YLT4
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS07135
gene id: 1904616:BFF78_RS07135
uniprot id: A0A1D7Y5G4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS13020
gene id: 1904616:BFF78_RS13020
uniprot id: A0A1D7Y889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1904616:BFF78 RS27745
gene id: 1904616:BFF78_RS27745
uniprot id: A0A1D7YG73
names: Similarity
messages: Belongs to the FPG family.

1904616:BFF78 RS31645
gene id: 1904616:BFF78_RS31645
uniprot id: A0A1D7YHB1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1904616:BFF78 RS12600
gene id: 1904616:BFF78_RS12600
uniprot id: A0A1D7Y8E2
names: Similarity
messages: Belongs to the ribF family.

1904616:BFF78 RS17605
gene id: 1904616:BFF78_RS17605
uniprot id: A0A1D7YNG8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS23325
gene id: 1904616:BFF78_RS23325
uniprot id: A0A1D7YDA6
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1904616:BFF78 RS07195
gene id: 1904616:BFF78_RS07195
uniprot id: A0A1D7Y5H8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1904616:BFF78 RS10040
gene id: 1904616:BFF78_RS10040
uniprot id: A0A1D7Y794
names: Similarity
messages: Belongs to the IucA/IucC family.

1904616:BFF78 RS19840
gene id: 1904616:BFF78_RS19840
uniprot id: A0A1D7YBL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1904616:BFF78 RS11275
gene id: 1904616:BFF78_RS11275
uniprot id: A0A1D7Y7E7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS01810
gene id: 1904616:BFF78_RS01810
uniprot id: A0A1D7Y354
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1904616:BFF78 RS10545
gene id: 1904616:BFF78_RS10545
uniprot id: A0A1D7Y725
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1904616:BFF78 RS28240
gene id: 1904616:BFF78_RS28240
uniprot id: A0A1D7YFT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1904616:BFF78 RS30495
gene id: 1904616:BFF78_RS30495
uniprot id: A0A1D7YH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1904616:BFF78 RS23875
gene id: 1904616:BFF78_RS23875
uniprot id: A0A1D7YDJ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS28270
gene id: 1904616:BFF78_RS28270
uniprot id: A0A1D7YFN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1904616:BFF78 RS35950
gene id: 1904616:BFF78_RS35950
uniprot id: A0A1D7YJH9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1904616:BFF78 RS06790
gene id: 1904616:BFF78_RS06790
uniprot id: A0A1D7Y5D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS31450
gene id: 1904616:BFF78_RS31450
uniprot id: A0A1D7YHE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1904616:BFF78 RS29730
gene id: 1904616:BFF78_RS29730
uniprot id: A0A1D7YGE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS14245
gene id: 1904616:BFF78_RS14245
uniprot id: A0A1D7Y988
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1904616:BFF78 RS32970
gene id: 1904616:BFF78_RS32970
uniprot id: A0A1D7YIS7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS02445
gene id: 1904616:BFF78_RS02445
uniprot id: A0A1D7Y3N9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1904616:BFF78 RS35340
gene id: 1904616:BFF78_RS35340
uniprot id: A0A1D7YJ75
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS28250
gene id: 1904616:BFF78_RS28250
uniprot id: A0A1D7YFN0
names: Similarity
messages: Belongs to the DapA family.

1904616:BFF78 RS28110
gene id: 1904616:BFF78_RS28110
uniprot id: A0A1D7YFJ7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1904616:BFF78 RS05110
gene id: 1904616:BFF78_RS05110
uniprot id: A0A1D7Y4K8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS17470
gene id: 1904616:BFF78_RS17470
uniprot id: A0A1D7YAG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1904616:BFF78 RS11475
gene id: 1904616:BFF78_RS11475
uniprot id: A0A1D7Y7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS00720
gene id: 1904616:BFF78_RS00720
uniprot id: A0A1D7YML1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS14020
gene id: 1904616:BFF78_RS14020
uniprot id: A0A1D7Y8Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS15195
gene id: 1904616:BFF78_RS15195
uniprot id: A0A1D7Y9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1904616:BFF78 RS06615
gene id: 1904616:BFF78_RS06615
uniprot id: A0A1D7Y5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1904616:BFF78 RS37610
gene id: 1904616:BFF78_RS37610
uniprot id: A0A1D7YKG7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1904616:BFF78 RS16960
gene id: 1904616:BFF78_RS16960
uniprot id: A0A1D7YA67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1904616:BFF78 RS23740
gene id: 1904616:BFF78_RS23740
uniprot id: A0A1D7YDI5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1904616:BFF78 RS19915
gene id: 1904616:BFF78_RS19915
uniprot id: A0A1D7YBZ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS28915
gene id: 1904616:BFF78_RS28915
uniprot id: A0A1D7YFZ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS14750
gene id: 1904616:BFF78_RS14750
uniprot id: A0A1D7Y954
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1904616:BFF78 RS16660
gene id: 1904616:BFF78_RS16660
uniprot id: A0A1D7YA14
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS21800
gene id: 1904616:BFF78_RS21800
uniprot id: A0A1D7YCL0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS34710
gene id: 1904616:BFF78_RS34710
uniprot id: A0A1D7YJ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1904616:BFF78 RS28365
gene id: 1904616:BFF78_RS28365
uniprot id: A0A1D7YFP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1904616:BFF78 RS21685
gene id: 1904616:BFF78_RS21685
uniprot id: A0A1D7YDC6
names: Similarity
messages: Belongs to the ice-binding protein family.

1904616:BFF78 RS40955
gene id: 1904616:BFF78_RS40955
uniprot id: A0A1D7YLW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1904616:BFF78 RS11635
gene id: 1904616:BFF78_RS11635
uniprot id: A0A1D7Y7Z0
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1904616:BFF78 RS35590
gene id: 1904616:BFF78_RS35590
uniprot id: A0A1D7YJI5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS12455
gene id: 1904616:BFF78_RS12455
uniprot id: A0A1D7Y801
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1904616:BFF78 RS18030
gene id: 1904616:BFF78_RS18030
uniprot id: A0A1D7YBJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS33045
gene id: 1904616:BFF78_RS33045
uniprot id: A0A1D7YI96
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS10535
gene id: 1904616:BFF78_RS10535
uniprot id: A0A1D7Y7D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1904616:BFF78 RS05420
gene id: 1904616:BFF78_RS05420
uniprot id: A0A1D7Y4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS24625
gene id: 1904616:BFF78_RS24625
uniprot id: A0A1D7YDW7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS09375
gene id: 1904616:BFF78_RS09375
uniprot id: A0A1D7Y6Z8
names: Similarity
messages: Belongs to the AAA ATPase family.

1904616:BFF78 RS34405
gene id: 1904616:BFF78_RS34405
uniprot id: A0A1D7YJH3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1904616:BFF78 RS01730
gene id: 1904616:BFF78_RS01730
uniprot id: A0A1D7Y306
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS13985
gene id: 1904616:BFF78_RS13985
uniprot id: A0A1D7YN88
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS12385
gene id: 1904616:BFF78_RS12385
uniprot id: A0A1D7Y8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1904616:BFF78 RS21695
gene id: 1904616:BFF78_RS21695
uniprot id: A0A1D7YPA5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS20555
gene id: 1904616:BFF78_RS20555
uniprot id: A0A1D7YBY4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS19845
gene id: 1904616:BFF78_RS19845
uniprot id: A0A1D7YBW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1904616:BFF78 RS40005
gene id: 1904616:BFF78_RS40005
uniprot id: A0A1D7YLF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1904616:BFF78 RS29105
gene id: 1904616:BFF78_RS29105
uniprot id: A0A1D7YGA9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1904616:BFF78 RS32040
gene id: 1904616:BFF78_RS32040
uniprot id: A0A1D7YHJ7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1904616:BFF78 RS30330
gene id: 1904616:BFF78_RS30330
uniprot id: A0A1D7YGM0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1904616:BFF78 RS30035
gene id: 1904616:BFF78_RS30035
uniprot id: A0A1D7YGJ2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1904616:BFF78 RS08685
gene id: 1904616:BFF78_RS08685
uniprot id: A0A1D7Y6L4
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1904616:BFF78 RS36895
gene id: 1904616:BFF78_RS36895
uniprot id: A0A1D7YK21
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1904616:BFF78 RS33395
gene id: 1904616:BFF78_RS33395
uniprot id: A0A1D7YI92
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1904616:BFF78 RS01460
gene id: 1904616:BFF78_RS01460
uniprot id: A0A1D7Y2W3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS17490
gene id: 1904616:BFF78_RS17490
uniprot id: A0A1D7YBA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1904616:BFF78 RS20305
gene id: 1904616:BFF78_RS20305
uniprot id: A0A1D7YBT0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1904616:BFF78 RS34245
gene id: 1904616:BFF78_RS34245
uniprot id: A0A1D7YIW4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1904616:BFF78 RS31730
gene id: 1904616:BFF78_RS31730
uniprot id: A0A1D7YHE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1904616:BFF78 RS36145
gene id: 1904616:BFF78_RS36145
uniprot id: A0A1D7YJK8
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

1904616:BFF78 RS19425
gene id: 1904616:BFF78_RS19425
uniprot id: A0A1D7YBE5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1904616:BFF78 RS31345
gene id: 1904616:BFF78_RS31345
uniprot id: A0A1D7YH60
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS31120
gene id: 1904616:BFF78_RS31120
uniprot id: A0A1D7YH40
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1904616:BFF78 RS40620
gene id: 1904616:BFF78_RS40620
uniprot id: A0A1D7YMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS28515
gene id: 1904616:BFF78_RS28515
uniprot id: A0A1D7YG34
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS30650
gene id: 1904616:BFF78_RS30650
uniprot id: A0A1D7YGV9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1904616:BFF78 RS18385
gene id: 1904616:BFF78_RS18385
uniprot id: A0A1D7YB36
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS03945
gene id: 1904616:BFF78_RS03945
uniprot id: A0A1D7Y401
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS12120
gene id: 1904616:BFF78_RS12120
uniprot id: A0A1D7Y7U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1904616:BFF78 RS30990
gene id: 1904616:BFF78_RS30990
uniprot id: A0A1D7YH16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1904616:BFF78 RS24845
gene id: 1904616:BFF78_RS24845
uniprot id: A0A1D7YE68
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1904616:BFF78 RS23595
gene id: 1904616:BFF78_RS23595
uniprot id: A0A1D7YDM6
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS22705
gene id: 1904616:BFF78_RS22705
uniprot id: A0A1D7YD01
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1904616:BFF78 RS26825
gene id: 1904616:BFF78_RS26825
uniprot id: A0A1D7YEZ2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21065
gene id: 1904616:BFF78_RS21065
uniprot id: A0A1D7YC82
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS07425
gene id: 1904616:BFF78_RS07425
uniprot id: A0A1D7Y5P7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS25560
gene id: 1904616:BFF78_RS25560
uniprot id: A0A1D7YEC2
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1904616:BFF78 RS08810
gene id: 1904616:BFF78_RS08810
uniprot id: A0A1D7Y6B9
names: Similarity
messages: Belongs to the TPP enzyme family.

1904616:BFF78 RS29580
gene id: 1904616:BFF78_RS29580
uniprot id: A0A1D7YGG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 54 family.

1904616:BFF78 RS11210
gene id: 1904616:BFF78_RS11210
uniprot id: A0A1D7Y7C7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1904616:BFF78 RS37155
gene id: 1904616:BFF78_RS37155
uniprot id: A0A1D7YK93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1904616:BFF78 RS13455
gene id: 1904616:BFF78_RS13455
uniprot id: A0A1D7Y8N5
names: Similarity
messages: Belongs to the agmatine deiminase family.

1904616:BFF78 RS12360
gene id: 1904616:BFF78_RS12360
uniprot id: A0A1D7Y8E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS16530
gene id: 1904616:BFF78_RS16530
uniprot id: A0A1D7Y9Z7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS08965
gene id: 1904616:BFF78_RS08965
uniprot id: A0A1D7Y721
names: Similarity
messages: Belongs to the peptidase S66 family.

1904616:BFF78 RS40485
gene id: 1904616:BFF78_RS40485
uniprot id: A0A1D7YLN2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS29595
gene id: 1904616:BFF78_RS29595
uniprot id: A0A1D7YGL9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS30405
gene id: 1904616:BFF78_RS30405
uniprot id: A0A1D7YGX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1904616:BFF78 RS31675
gene id: 1904616:BFF78_RS31675
uniprot id: A0A1D7YHI2
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1904616:BFF78 RS38240
gene id: 1904616:BFF78_RS38240
uniprot id: A0A1D7YKQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS28200
gene id: 1904616:BFF78_RS28200
uniprot id: A0A1D7YFY0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1904616:BFF78 RS37330
gene id: 1904616:BFF78_RS37330
uniprot id: A0A1D7YK41
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS19160
gene id: 1904616:BFF78_RS19160
uniprot id: A0A1D7YP50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1904616:BFF78 RS36455
gene id: 1904616:BFF78_RS36455
uniprot id: A0A1D7YJV0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS16525
gene id: 1904616:BFF78_RS16525
uniprot id: A0A1D7YAE9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS34185
gene id: 1904616:BFF78_RS34185
uniprot id: A0A1D7YIS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1904616:BFF78 RS34230
gene id: 1904616:BFF78_RS34230
uniprot id: A0A1D7YJE1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1904616:BFF78 RS29550
gene id: 1904616:BFF78_RS29550
uniprot id: A0A1D7YGA8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41450
gene id: 1904616:BFF78_RS41450
uniprot id: A0A1D7YM45
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1904616:BFF78 RS13885
gene id: 1904616:BFF78_RS13885
uniprot id: A0A1D7Y8P0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1904616:BFF78 RS07275
gene id: 1904616:BFF78_RS07275
uniprot id: A0A1D7Y673
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1904616:BFF78 RS06235
gene id: 1904616:BFF78_RS06235
uniprot id: A0A1D7Y5H6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1904616:BFF78 RS31815
gene id: 1904616:BFF78_RS31815
uniprot id: A0A1D7YHL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS09085
gene id: 1904616:BFF78_RS09085
uniprot id: A0A1D7Y6I8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1904616:BFF78 RS20260
gene id: 1904616:BFF78_RS20260
uniprot id: A0A1D7YC54
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1904616:BFF78 RS19490
gene id: 1904616:BFF78_RS19490
uniprot id: A0A1D7YBF1
names: Similarity
messages: Belongs to the GSP E family.

1904616:BFF78 RS26595
gene id: 1904616:BFF78_RS26595
uniprot id: A0A1D7YP74
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS11240
gene id: 1904616:BFF78_RS11240
uniprot id: A0A1D7Y7I4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS35975
gene id: 1904616:BFF78_RS35975
uniprot id: A0A1D7YJI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS06710
gene id: 1904616:BFF78_RS06710
uniprot id: A0A1D7Y5W5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1904616:BFF78 RS31785
gene id: 1904616:BFF78_RS31785
uniprot id: A0A1D7YHF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

1904616:BFF78 RS13495
gene id: 1904616:BFF78_RS13495
uniprot id: A0A1D7Y9A5
names: Cofactor
messages: Binds 1 FAD per subunit.

1904616:BFF78 RS30435
gene id: 1904616:BFF78_RS30435
uniprot id: A0A1D7YGR1
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1904616:BFF78 RS27040
gene id: 1904616:BFF78_RS27040
uniprot id: A0A1D7YP59
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1904616:BFF78 RS29060
gene id: 1904616:BFF78_RS29060
uniprot id: A0A1D7YG04
names: Similarity
messages: Belongs to the HIBADH-related family.

1904616:BFF78 RS23505
gene id: 1904616:BFF78_RS23505
uniprot id: A0A1D7YDD7
names: Similarity
messages: Belongs to the CutC family.

1904616:BFF78 RS21860
gene id: 1904616:BFF78_RS21860
uniprot id: A0A1D7YCL9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS19335
gene id: 1904616:BFF78_RS19335
uniprot id: A0A1D7YBT8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS24675
gene id: 1904616:BFF78_RS24675
uniprot id: A0A1D7YE90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1904616:BFF78 RS32360
gene id: 1904616:BFF78_RS32360
uniprot id: A0A1D7YHW3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1904616:BFF78 RS18640
gene id: 1904616:BFF78_RS18640
uniprot id: A0A1D7YB08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS30765
gene id: 1904616:BFF78_RS30765
uniprot id: A0A1D7YGX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1904616:BFF78 RS00110
gene id: 1904616:BFF78_RS00110
uniprot id: A0A1D7Y2T5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS17645
gene id: 1904616:BFF78_RS17645
uniprot id: A0A1D7YAZ6
names: Similarity
messages: Belongs to the UPF0336 family.

1904616:BFF78 RS09930
gene id: 1904616:BFF78_RS09930
uniprot id: A0A1D7Y6V2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS32550
gene id: 1904616:BFF78_RS32550
uniprot id: A0A1D7YI08
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS04205
gene id: 1904616:BFF78_RS04205
uniprot id: A0A1D7Y446
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS05105
gene id: 1904616:BFF78_RS05105
uniprot id: A0A1D7Y4N8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1904616:BFF78 RS14535
gene id: 1904616:BFF78_RS14535
uniprot id: A0A1D7Y920
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1904616:BFF78 RS34040
gene id: 1904616:BFF78_RS34040
uniprot id: A0A1D7YIQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS28530
gene id: 1904616:BFF78_RS28530
uniprot id: A0A1D7YG07
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS26975
gene id: 1904616:BFF78_RS26975
uniprot id: A0A1D7YF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1904616:BFF78 RS16645
gene id: 1904616:BFF78_RS16645
uniprot id: A0A1D7YAH1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1904616:BFF78 RS19355
gene id: 1904616:BFF78_RS19355
uniprot id: A0A1D7YBP7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1904616:BFF78 RS28995
gene id: 1904616:BFF78_RS28995
uniprot id: A0A1D7YG00
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS38950
gene id: 1904616:BFF78_RS38950
uniprot id: A0A1D7YL59
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS31150
gene id: 1904616:BFF78_RS31150
uniprot id: A0A1D7YH28
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24890
gene id: 1904616:BFF78_RS24890
uniprot id: A0A1D7YEE2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS05095
gene id: 1904616:BFF78_RS05095
uniprot id: A0A1D7Y4J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1904616:BFF78 RS41300
gene id: 1904616:BFF78_RS41300
uniprot id: A0A1D7YQ58
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1904616:BFF78 RS30280
gene id: 1904616:BFF78_RS30280
uniprot id: A0A1D7YHE4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1904616:BFF78 RS26870
gene id: 1904616:BFF78_RS26870
uniprot id: A0A1D7YF06
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS30315
gene id: 1904616:BFF78_RS30315
uniprot id: A0A1D7YGP3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS00595
gene id: 1904616:BFF78_RS00595
uniprot id: A0A1D7Y324
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1904616:BFF78 RS25920
gene id: 1904616:BFF78_RS25920
uniprot id: A0A1D7YEV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1904616:BFF78 RS21375
gene id: 1904616:BFF78_RS21375
uniprot id: A0A1D7YNQ7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS15335
gene id: 1904616:BFF78_RS15335
uniprot id: A0A1D7Y9F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1904616:BFF78 RS03320
gene id: 1904616:BFF78_RS03320
uniprot id: A0A1D7Y448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EfeM/EfeO family.
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1904616:BFF78 RS03005
gene id: 1904616:BFF78_RS03005
uniprot id: A0A1D7Y3L7
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1904616:BFF78 RS02155
gene id: 1904616:BFF78_RS02155
uniprot id: A0A1D7Y375
names: Similarity
messages: Belongs to the universal stress protein A family.

1904616:BFF78 RS13590
gene id: 1904616:BFF78_RS13590
uniprot id: A0A1D7Y8J4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1904616:BFF78 RS34255
gene id: 1904616:BFF78_RS34255
uniprot id: A0A1D7YIU8
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1904616:BFF78 RS16560
gene id: 1904616:BFF78_RS16560
uniprot id: A0A1D7YA08
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS06715
gene id: 1904616:BFF78_RS06715
uniprot id: A0A1D7Y5P5
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1904616:BFF78 RS29985
gene id: 1904616:BFF78_RS29985
uniprot id: A0A1D7YGQ5
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS05920
gene id: 1904616:BFF78_RS05920
uniprot id: A0A1D7Y4W0
names: Similarity
messages: Belongs to the proline racemase family.

1904616:BFF78 RS12630
gene id: 1904616:BFF78_RS12630
uniprot id: A0A1D7Y8I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1904616:BFF78 RS21275
gene id: 1904616:BFF78_RS21275
uniprot id: A0A1D7YCI3
names: Similarity
messages: Belongs to the thioredoxin family.

1904616:BFF78 RS15070
gene id: 1904616:BFF78_RS15070
uniprot id: A0A1D7Y9G0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS26495
gene id: 1904616:BFF78_RS26495
uniprot id: A0A1D7YF26
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS11840
gene id: 1904616:BFF78_RS11840
uniprot id: A0A1D7Y7W3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1904616:BFF78 RS17505
gene id: 1904616:BFF78_RS17505
uniprot id: A0A1D7YAN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1904616:BFF78 RS06105
gene id: 1904616:BFF78_RS06105
uniprot id: A0A1D7Y4Z5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1904616:BFF78 RS27850
gene id: 1904616:BFF78_RS27850
uniprot id: A0A1D7YFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1904616:BFF78 RS12565
gene id: 1904616:BFF78_RS12565
uniprot id: A0A1D7Y872
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1904616:BFF78 RS15835
gene id: 1904616:BFF78_RS15835
uniprot id: A0A1D7Y9N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1904616:BFF78 RS24670
gene id: 1904616:BFF78_RS24670
uniprot id: A0A1D7YDY8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS20060
gene id: 1904616:BFF78_RS20060
uniprot id: A0A1D7YC48
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS31405
gene id: 1904616:BFF78_RS31405
uniprot id: A0A1D7YH81
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1904616:BFF78 RS17970
gene id: 1904616:BFF78_RS17970
uniprot id: A0A1D7YAP6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS34175
gene id: 1904616:BFF78_RS34175
uniprot id: A0A1D7YJD3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1904616:BFF78 RS23955
gene id: 1904616:BFF78_RS23955
uniprot id: A0A1D7YDS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS25840
gene id: 1904616:BFF78_RS25840
uniprot id: A0A1D7YEH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS19940
gene id: 1904616:BFF78_RS19940
uniprot id: A0A1D7YNQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1904616:BFF78 RS38325
gene id: 1904616:BFF78_RS38325
uniprot id: A0A1D7YKL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1904616:BFF78 RS33230
gene id: 1904616:BFF78_RS33230
uniprot id: A0A1D7YI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1904616:BFF78 RS19030
gene id: 1904616:BFF78_RS19030
uniprot id: A0A1D7YB76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1904616:BFF78 RS32235
gene id: 1904616:BFF78_RS32235
uniprot id: A0A1D7YIE0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21255
gene id: 1904616:BFF78_RS21255
uniprot id: A0A1D7YCA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1904616:BFF78 RS28990
gene id: 1904616:BFF78_RS28990
uniprot id: A0A1D7YG90
names: Similarity
messages: Belongs to the aldose epimerase family.

1904616:BFF78 RS22245
gene id: 1904616:BFF78_RS22245
uniprot id: A0A1D7YD17
names: Similarity
messages: Belongs to the GARS family.

1904616:BFF78 RS19955
gene id: 1904616:BFF78_RS19955
uniprot id: A0A1D7YBU3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS12910
gene id: 1904616:BFF78_RS12910
uniprot id: A0A1D7Y864
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS12135
gene id: 1904616:BFF78_RS12135
uniprot id: A0A1D7Y8A5
names: Similarity
messages: Belongs to the IucA/IucC family.

1904616:BFF78 RS10650
gene id: 1904616:BFF78_RS10650
uniprot id: A0A1D7Y7V7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS13380
gene id: 1904616:BFF78_RS13380
uniprot id: A0A1D7Y8E8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1904616:BFF78 RS13580
gene id: 1904616:BFF78_RS13580
uniprot id: A0A1D7Y8I5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1904616:BFF78 RS06910
gene id: 1904616:BFF78_RS06910
uniprot id: A0A1D7Y5C9
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1904616:BFF78 RS10315
gene id: 1904616:BFF78_RS10315
uniprot id: A0A1D7Y6X5
names: Similarity
messages: Belongs to the CdaR family.

1904616:BFF78 RS35945
gene id: 1904616:BFF78_RS35945
uniprot id: A0A1D7YJP6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1904616:BFF78 RS17835
gene id: 1904616:BFF78_RS17835
uniprot id: A0A1D7YAM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS12980
gene id: 1904616:BFF78_RS12980
uniprot id: A0A1D7Y8P3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1904616:BFF78 RS05750
gene id: 1904616:BFF78_RS05750
uniprot id: A0A1D7Y4Z7
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1904616:BFF78 RS21355
gene id: 1904616:BFF78_RS21355
uniprot id: A0A1D7YCC8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1904616:BFF78 RS34380
gene id: 1904616:BFF78_RS34380
uniprot id: A0A1D7YIW8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS00855
gene id: 1904616:BFF78_RS00855
uniprot id: A0A1D7Y2Q3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS07070
gene id: 1904616:BFF78_RS07070
uniprot id: A0A1D7Y5Q3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1904616:BFF78 RS33050
gene id: 1904616:BFF78_RS33050
uniprot id: A0A1D7YI33
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS40920
gene id: 1904616:BFF78_RS40920
uniprot id: A0A1D7YLV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS06645
gene id: 1904616:BFF78_RS06645
uniprot id: A0A1D7YMU8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1904616:BFF78 RS34295
gene id: 1904616:BFF78_RS34295
uniprot id: A0A1D7YIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS39790
gene id: 1904616:BFF78_RS39790
uniprot id: A0A1D7YLF6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1904616:BFF78 RS14865
gene id: 1904616:BFF78_RS14865
uniprot id: A0A1D7Y9L4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS11480
gene id: 1904616:BFF78_RS11480
uniprot id: A0A1D7Y7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS25730
gene id: 1904616:BFF78_RS25730
uniprot id: A0A1D7YEF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS07180
gene id: 1904616:BFF78_RS07180
uniprot id: A0A1D7Y5K3
names: Similarity
messages: Belongs to the thioesterase family.

1904616:BFF78 RS28000
gene id: 1904616:BFF78_RS28000
uniprot id: A0A1D7YFS0
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1904616:BFF78 RS03695
gene id: 1904616:BFF78_RS03695
uniprot id: A0A1D7Y3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1904616:BFF78 RS37760
gene id: 1904616:BFF78_RS37760
uniprot id: A0A1D7YKH8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS11650
gene id: 1904616:BFF78_RS11650
uniprot id: A0A1D7Y8D3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1904616:BFF78 RS14905
gene id: 1904616:BFF78_RS14905
uniprot id: A0A1D7Y9D6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1904616:BFF78 RS12560
gene id: 1904616:BFF78_RS12560
uniprot id: A0A1D7Y885
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1904616:BFF78 RS41115
gene id: 1904616:BFF78_RS41115
uniprot id: A0A1D7YM70
names: Similarity
messages: Belongs to the IucA/IucC family.

1904616:BFF78 RS16025
gene id: 1904616:BFF78_RS16025
uniprot id: A0A1D7YND9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS23310
gene id: 1904616:BFF78_RS23310
uniprot id: A0A1D7YDJ5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1904616:BFF78 RS14070
gene id: 1904616:BFF78_RS14070
uniprot id: A0A1D7YNA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS33220
gene id: 1904616:BFF78_RS33220
uniprot id: A0A1D7YI51
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1904616:BFF78 RS09700
gene id: 1904616:BFF78_RS09700
uniprot id: A0A1D7Y6Q2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS34430
gene id: 1904616:BFF78_RS34430
uniprot id: A0A1D7YIR0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS02745
gene id: 1904616:BFF78_RS02745
uniprot id: A0A1D7Y3U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS23690
gene id: 1904616:BFF78_RS23690
uniprot id: A0A1D7YDG7
names: Similarity
messages: Belongs to the FemABX family.

1904616:BFF78 RS19140
gene id: 1904616:BFF78_RS19140
uniprot id: A0A1D7YB90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1904616:BFF78 RS26620
gene id: 1904616:BFF78_RS26620
uniprot id: A0A1D7YEW7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS31885
gene id: 1904616:BFF78_RS31885
uniprot id: A0A1D7YHM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1904616:BFF78 RS20395
gene id: 1904616:BFF78_RS20395
uniprot id: A0A1D7YCA9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS08705
gene id: 1904616:BFF78_RS08705
uniprot id: A0A1D7Y6G0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS06545
gene id: 1904616:BFF78_RS06545
uniprot id: A0A1D7Y587
names: Similarity
messages: Belongs to the peptidase M1 family.

1904616:BFF78 RS39160
gene id: 1904616:BFF78_RS39160
uniprot id: A0A1D7YLM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1904616:BFF78 RS29660
gene id: 1904616:BFF78_RS29660
uniprot id: A0A1D7YGC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS19145
gene id: 1904616:BFF78_RS19145
uniprot id: A0A1D7YB94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1904616:BFF78 RS20690
gene id: 1904616:BFF78_RS20690
uniprot id: A0A1D7YCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1904616:BFF78 RS15175
gene id: 1904616:BFF78_RS15175
uniprot id: A0A1D7Y9C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS17650
gene id: 1904616:BFF78_RS17650
uniprot id: A0A1D7YAJ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1904616:BFF78 RS39835
gene id: 1904616:BFF78_RS39835
uniprot id: A0A1D7YLH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1904616:BFF78 RS00740
gene id: 1904616:BFF78_RS00740
uniprot id: A0A1D7Y2K4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS18380
gene id: 1904616:BFF78_RS18380
uniprot id: A0A1D7YB09
names: Similarity
messages: Belongs to the UbiD family.

1904616:BFF78 RS10640
gene id: 1904616:BFF78_RS10640
uniprot id: A0A1D7Y732
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1904616:BFF78 RS06465
gene id: 1904616:BFF78_RS06465
uniprot id: A0A1D7Y553
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS35535
gene id: 1904616:BFF78_RS35535
uniprot id: A0A1D7YJF1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS09065
gene id: 1904616:BFF78_RS09065
uniprot id: A0A1D7Y6D3
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1904616:BFF78 RS28120
gene id: 1904616:BFF78_RS28120
uniprot id: A0A1D7YFW3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS32035
gene id: 1904616:BFF78_RS32035
uniprot id: A0A1D7YPD0
names: Similarity
messages: Belongs to the CobH/CbiC family.

1904616:BFF78 RS30295
gene id: 1904616:BFF78_RS30295
uniprot id: A0A1D7YPC2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS26505
gene id: 1904616:BFF78_RS26505
uniprot id: A0A1D7YET5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1904616:BFF78 RS05180
gene id: 1904616:BFF78_RS05180
uniprot id: A0A1D7Y4Q5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21980
gene id: 1904616:BFF78_RS21980
uniprot id: A0A1D7YCP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1904616:BFF78 RS27810
gene id: 1904616:BFF78_RS27810
uniprot id: A0A1D7YFR5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1904616:BFF78 RS25355
gene id: 1904616:BFF78_RS25355
uniprot id: A0A1D7YEM2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1904616:BFF78 RS14010
gene id: 1904616:BFF78_RS14010
uniprot id: A0A1D7Y963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS40025
gene id: 1904616:BFF78_RS40025
uniprot id: A0A1D7YLK0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1904616:BFF78 RS32995
gene id: 1904616:BFF78_RS32995
uniprot id: A0A1D7YI86
names: Similarity
messages: Belongs to the peptidase S45 family.

1904616:BFF78 RS07550
gene id: 1904616:BFF78_RS07550
uniprot id: A0A1D7Y5X7
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS06505
gene id: 1904616:BFF78_RS06505
uniprot id: A0A1D7Y592
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS00510
gene id: 1904616:BFF78_RS00510
uniprot id: A0A1D7Y2G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1904616:BFF78 RS32945
gene id: 1904616:BFF78_RS32945
uniprot id: A0A1D7YPE5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS01760
gene id: 1904616:BFF78_RS01760
uniprot id: A0A1D7Y302
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS10870
gene id: 1904616:BFF78_RS10870
uniprot id: A0A1D7Y7Z4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1904616:BFF78 RS20985
gene id: 1904616:BFF78_RS20985
uniprot id: A0A1D7YCD5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS40600
gene id: 1904616:BFF78_RS40600
uniprot id: A0A1D7YLR5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1904616:BFF78 RS00610
gene id: 1904616:BFF78_RS00610
uniprot id: A0A1D7Y2W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1904616:BFF78 RS27515
gene id: 1904616:BFF78_RS27515
uniprot id: A0A1D7YG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS05405
gene id: 1904616:BFF78_RS05405
uniprot id: A0A1D7Y549
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS10820
gene id: 1904616:BFF78_RS10820
uniprot id: A0A1D7Y7M8
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

1904616:BFF78 RS05940
gene id: 1904616:BFF78_RS05940
uniprot id: A0A1D7Y4Z0
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS42165
gene id: 1904616:BFF78_RS42165
uniprot id: A0A1D7YMP2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS03795
gene id: 1904616:BFF78_RS03795
uniprot id: A0A1D7Y3X8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS39185
gene id: 1904616:BFF78_RS39185
uniprot id: A0A1D7YL85
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1904616:BFF78 RS20510
gene id: 1904616:BFF78_RS20510
uniprot id: A0A1D7YBY0
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS21430
gene id: 1904616:BFF78_RS21430
uniprot id: A0A1D7YCJ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS23375
gene id: 1904616:BFF78_RS23375
uniprot id: A0A1D7YDB8
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1904616:BFF78 RS34125
gene id: 1904616:BFF78_RS34125
uniprot id: A0A1D7YJC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS38300
gene id: 1904616:BFF78_RS38300
uniprot id: A0A1D7YKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1904616:BFF78 RS16715
gene id: 1904616:BFF78_RS16715
uniprot id: A0A1D7YA24
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1904616:BFF78 RS32075
gene id: 1904616:BFF78_RS32075
uniprot id: A0A1D7YIA5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1904616:BFF78 RS07150
gene id: 1904616:BFF78_RS07150
uniprot id: A0A1D7Y653
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS00090
gene id: 1904616:BFF78_RS00090
uniprot id: A0A1D7Y2D5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1904616:BFF78 RS39895
gene id: 1904616:BFF78_RS39895
uniprot id: A0A1D7YLD2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1904616:BFF78 RS07630
gene id: 1904616:BFF78_RS07630
uniprot id: A0A1D7Y5Z4
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS31005
gene id: 1904616:BFF78_RS31005
uniprot id: A0A1D7YH85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1904616:BFF78 RS30410
gene id: 1904616:BFF78_RS30410
uniprot id: A0A1D7YGY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1904616:BFF78 RS02325
gene id: 1904616:BFF78_RS02325
uniprot id: A0A1D7Y3L4
names: Similarity
messages: Belongs to the DSD1 family.

1904616:BFF78 RS19135
gene id: 1904616:BFF78_RS19135
uniprot id: A0A1D7YBN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1904616:BFF78 RS06350
gene id: 1904616:BFF78_RS06350
uniprot id: A0A1D7Y5Q1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS11640
gene id: 1904616:BFF78_RS11640
uniprot id: A0A1D7Y7L5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1904616:BFF78 RS13975
gene id: 1904616:BFF78_RS13975
uniprot id: A0A1D7Y939
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS03645
gene id: 1904616:BFF78_RS03645
uniprot id: A0A1D7YMY2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS35245
gene id: 1904616:BFF78_RS35245
uniprot id: A0A1D7YJB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1904616:BFF78 RS03595
gene id: 1904616:BFF78_RS03595
uniprot id: A0A1D7Y3V1
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1904616:BFF78 RS28480
gene id: 1904616:BFF78_RS28480
uniprot id: A0A1D7YFS1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1904616:BFF78 RS28290
gene id: 1904616:BFF78_RS28290
uniprot id: A0A1D7YFU7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS33880
gene id: 1904616:BFF78_RS33880
uniprot id: A0A1D7YIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1904616:BFF78 RS10810
gene id: 1904616:BFF78_RS10810
uniprot id: A0A1D7Y7Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS21110
gene id: 1904616:BFF78_RS21110
uniprot id: A0A1D7YCF1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS28360
gene id: 1904616:BFF78_RS28360
uniprot id: A0A1D7YP93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1904616:BFF78 RS06755
gene id: 1904616:BFF78_RS06755
uniprot id: A0A1D7Y5A3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS33970
gene id: 1904616:BFF78_RS33970
uniprot id: A0A1D7YIR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1904616:BFF78 RS08280
gene id: 1904616:BFF78_RS08280
uniprot id: A0A1D7Y6N2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS28085
gene id: 1904616:BFF78_RS28085
uniprot id: A0A1D7YFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1904616:BFF78 RS21370
gene id: 1904616:BFF78_RS21370
uniprot id: A0A1D7YCT5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1904616:BFF78 RS13990
gene id: 1904616:BFF78_RS13990
uniprot id: A0A1D7Y943
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS15110
gene id: 1904616:BFF78_RS15110
uniprot id: A0A1D7Y9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS33780
gene id: 1904616:BFF78_RS33780
uniprot id: A0A1D7YIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1904616:BFF78 RS39375
gene id: 1904616:BFF78_RS39375
uniprot id: A0A1D7YL45
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS02020
gene id: 1904616:BFF78_RS02020
uniprot id: A0A1D7Y356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS27755
gene id: 1904616:BFF78_RS27755
uniprot id: A0A1D7YFK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1904616:BFF78 RS06640
gene id: 1904616:BFF78_RS06640
uniprot id: A0A1D7Y584
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1904616:BFF78 RS07665
gene id: 1904616:BFF78_RS07665
uniprot id: A0A1D7Y6D2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS25245
gene id: 1904616:BFF78_RS25245
uniprot id: A0A1D7YED2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1904616:BFF78 RS29890
gene id: 1904616:BFF78_RS29890
uniprot id: A0A1D7YGL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS13880
gene id: 1904616:BFF78_RS13880
uniprot id: A0A1D7Y8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS04450
gene id: 1904616:BFF78_RS04450
uniprot id: A0A1D7Y485
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS25065
gene id: 1904616:BFF78_RS25065
uniprot id: A0A1D7YEB8
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS35475
gene id: 1904616:BFF78_RS35475
uniprot id: A0A1D7YJG6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1904616:BFF78 RS28465
gene id: 1904616:BFF78_RS28465
uniprot id: A0A1D7YG22
names: Similarity
messages: Belongs to the Fur family.

1904616:BFF78 RS26830
gene id: 1904616:BFF78_RS26830
uniprot id: A0A1D7YF95
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS13620
gene id: 1904616:BFF78_RS13620
uniprot id: A0A1D7Y8Q8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1904616:BFF78 RS18800
gene id: 1904616:BFF78_RS18800
uniprot id: A0A1D7YNM8
names: Similarity
messages: Belongs to the histone deacetylase family.

1904616:BFF78 RS31615
gene id: 1904616:BFF78_RS31615
uniprot id: A0A1D7YHJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS25635
gene id: 1904616:BFF78_RS25635
uniprot id: A0A1D7YEJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1904616:BFF78 RS13260
gene id: 1904616:BFF78_RS13260
uniprot id: A0A1D7Y8R9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1904616:BFF78 RS14035
gene id: 1904616:BFF78_RS14035
uniprot id: A0A1D7Y950
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1904616:BFF78 RS17165
gene id: 1904616:BFF78_RS17165
uniprot id: A0A1D7YAH8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS01835
gene id: 1904616:BFF78_RS01835
uniprot id: A0A1D7Y3G5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1904616:BFF78 RS36555
gene id: 1904616:BFF78_RS36555
uniprot id: A0A1D7YJW9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1904616:BFF78 RS06420
gene id: 1904616:BFF78_RS06420
uniprot id: A0A1D7Y567
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

1904616:BFF78 RS33945
gene id: 1904616:BFF78_RS33945
uniprot id: A0A1D7YII1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS40915
gene id: 1904616:BFF78_RS40915
uniprot id: A0A1D7YM46
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1904616:BFF78 RS15770
gene id: 1904616:BFF78_RS15770
uniprot id: A0A1D7Y9M8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS13715
gene id: 1904616:BFF78_RS13715
uniprot id: A0A1D7Y919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS21475
gene id: 1904616:BFF78_RS21475
uniprot id: A0A1D7YCV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1904616:BFF78 RS26240
gene id: 1904616:BFF78_RS26240
uniprot id: A0A1D7YPA3
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1904616:BFF78 RS13250
gene id: 1904616:BFF78_RS13250
uniprot id: A0A1D7Y8J8
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

1904616:BFF78 RS25305
gene id: 1904616:BFF78_RS25305
uniprot id: A0A1D7YEL2
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1904616:BFF78 RS04260
gene id: 1904616:BFF78_RS04260
uniprot id: A0A1D7Y454
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS25565
gene id: 1904616:BFF78_RS25565
uniprot id: A0A1D7YF52
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1904616:BFF78 RS20850
gene id: 1904616:BFF78_RS20850
uniprot id: A0A1D7YC46
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1904616:BFF78 RS29120
gene id: 1904616:BFF78_RS29120
uniprot id: A0A1D7YGU5
names: Similarity
messages: Belongs to the CdaR family.

1904616:BFF78 RS38230
gene id: 1904616:BFF78_RS38230
uniprot id: A0A1D7YL67
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1904616:BFF78 RS18755
gene id: 1904616:BFF78_RS18755
uniprot id: A0A1D7YB35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1904616:BFF78 RS19035
gene id: 1904616:BFF78_RS19035
uniprot id: A0A1D7YC05
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1904616:BFF78 RS33925
gene id: 1904616:BFF78_RS33925
uniprot id: A0A1D7YIN5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS18440
gene id: 1904616:BFF78_RS18440
uniprot id: A0A1D7YAX8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS05575
gene id: 1904616:BFF78_RS05575
uniprot id: A0A1D7Y4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS33640
gene id: 1904616:BFF78_RS33640
uniprot id: A0A1D7YIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1904616:BFF78 RS16820
gene id: 1904616:BFF78_RS16820
uniprot id: A0A1D7YAK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS17045
gene id: 1904616:BFF78_RS17045
uniprot id: A0A1D7YAP1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS31175
gene id: 1904616:BFF78_RS31175
uniprot id: A0A1D7YH50
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1904616:BFF78 RS17585
gene id: 1904616:BFF78_RS17585
uniprot id: A0A1D7YAI7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1904616:BFF78 RS35240
gene id: 1904616:BFF78_RS35240
uniprot id: A0A1D7YJW2
names: Similarity
messages: Belongs to the IMPACT family.

1904616:BFF78 RS23960
gene id: 1904616:BFF78_RS23960
uniprot id: A0A1D7YDT3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1904616:BFF78 RS32785
gene id: 1904616:BFF78_RS32785
uniprot id: A0A1D7YHY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1904616:BFF78 RS18040
gene id: 1904616:BFF78_RS18040
uniprot id: A0A1D7YAV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1904616:BFF78 RS13415
gene id: 1904616:BFF78_RS13415
uniprot id: A0A1D7Y8H2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1904616:BFF78 RS21400
gene id: 1904616:BFF78_RS21400
uniprot id: A0A1D7YCE1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS11190
gene id: 1904616:BFF78_RS11190
uniprot id: A0A1D7Y7E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS23765
gene id: 1904616:BFF78_RS23765
uniprot id: A0A1D7YDI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS17595
gene id: 1904616:BFF78_RS17595
uniprot id: A0A1D7YBC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1904616:BFF78 RS35425
gene id: 1904616:BFF78_RS35425
uniprot id: A0A1D7YJE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS16570
gene id: 1904616:BFF78_RS16570
uniprot id: A0A1D7YA11
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1904616:BFF78 RS19530
gene id: 1904616:BFF78_RS19530
uniprot id: A0A1D7YP61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1904616:BFF78 RS02615
gene id: 1904616:BFF78_RS02615
uniprot id: A0A1D7Y3D7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1904616:BFF78 RS17860
gene id: 1904616:BFF78_RS17860
uniprot id: A0A1D7YB30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS23820
gene id: 1904616:BFF78_RS23820
uniprot id: A0A1D7YDI7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS04240
gene id: 1904616:BFF78_RS04240
uniprot id: A0A1D7Y459
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS35380
gene id: 1904616:BFF78_RS35380
uniprot id: A0A1D7YJ73
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24360
gene id: 1904616:BFF78_RS24360
uniprot id: A0A1D7YDT7
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1904616:BFF78 RS14130
gene id: 1904616:BFF78_RS14130
uniprot id: A0A1D7Y8Z8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1904616:BFF78 RS05255
gene id: 1904616:BFF78_RS05255
uniprot id: A0A1D7Y529
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS24790
gene id: 1904616:BFF78_RS24790
uniprot id: A0A1D7YE63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1904616:BFF78 RS38720
gene id: 1904616:BFF78_RS38720
uniprot id: A0A1D7YKX2
names: Similarity
messages: Belongs to the universal stress protein A family.

1904616:BFF78 RS07000
gene id: 1904616:BFF78_RS07000
uniprot id: A0A1D7Y5J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1904616:BFF78 RS34145
gene id: 1904616:BFF78_RS34145
uniprot id: A0A1D7YIL2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1904616:BFF78 RS38560
gene id: 1904616:BFF78_RS38560
uniprot id: A0A1D7YKW6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS11105
gene id: 1904616:BFF78_RS11105
uniprot id: A0A1D7YN93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1904616:BFF78 RS13660
gene id: 1904616:BFF78_RS13660
uniprot id: A0A1D7Y9D5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1904616:BFF78 RS32920
gene id: 1904616:BFF78_RS32920
uniprot id: A0A1D7YI71
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS25825
gene id: 1904616:BFF78_RS25825
uniprot id: A0A1D7YEP0
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1904616:BFF78 RS10000
gene id: 1904616:BFF78_RS10000
uniprot id: A0A1D7Y6U9
names: Subunit
messages: Homotetramer.

1904616:BFF78 RS04165
gene id: 1904616:BFF78_RS04165
uniprot id: A0A1D7Y445
names: Similarity
messages: Belongs to the peptidase S33 family.

1904616:BFF78 RS37820
gene id: 1904616:BFF78_RS37820
uniprot id: A0A1D7YKC0
names: Function
names: Similarity
messages: Belongs to the nitrile hydratase subunit beta family.
messages: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.

1904616:BFF78 RS40630
gene id: 1904616:BFF78_RS40630
uniprot id: A0A1D7YLV4
names: Similarity
messages: Belongs to the GcvT family.

1904616:BFF78 RS25915
gene id: 1904616:BFF78_RS25915
uniprot id: A0A1D7YFB0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1904616:BFF78 RS37040
gene id: 1904616:BFF78_RS37040
uniprot id: A0A1D7YJZ8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1904616:BFF78 RS35375
gene id: 1904616:BFF78_RS35375
uniprot id: A0A1D7YJD4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS15870
gene id: 1904616:BFF78_RS15870
uniprot id: A0A1D7YAI6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1904616:BFF78 RS07715
gene id: 1904616:BFF78_RS07715
uniprot id: A0A1D7Y5R9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS02910
gene id: 1904616:BFF78_RS02910
uniprot id: A0A1D7Y3J2
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1904616:BFF78 RS23465
gene id: 1904616:BFF78_RS23465
uniprot id: A0A1D7YP37
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS22925
gene id: 1904616:BFF78_RS22925
uniprot id: A0A1D7YD39
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS07780
gene id: 1904616:BFF78_RS07780
uniprot id: A0A1D7Y6E9
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS27615
gene id: 1904616:BFF78_RS27615
uniprot id: A0A1D7YFL0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1904616:BFF78 RS13520
gene id: 1904616:BFF78_RS13520
uniprot id: A0A1D7Y8H9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS13100
gene id: 1904616:BFF78_RS13100
uniprot id: A0A1D7Y8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1904616:BFF78 RS38540
gene id: 1904616:BFF78_RS38540
uniprot id: A0A1D7YKU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS26360
gene id: 1904616:BFF78_RS26360
uniprot id: A0A1D7YER8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1904616:BFF78 RS24580
gene id: 1904616:BFF78_RS24580
uniprot id: A0A1D7YEP1
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1904616:BFF78 RS21290
gene id: 1904616:BFF78_RS21290
uniprot id: A0A1D7YCC3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS32620
gene id: 1904616:BFF78_RS32620
uniprot id: A0A1D7YHW0
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1904616:BFF78 RS12390
gene id: 1904616:BFF78_RS12390
uniprot id: A0A1D7Y812
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1904616:BFF78 RS16535
gene id: 1904616:BFF78_RS16535
uniprot id: A0A1D7Y9Z5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1904616:BFF78 RS10605
gene id: 1904616:BFF78_RS10605
uniprot id: A0A1D7Y7J2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS33180
gene id: 1904616:BFF78_RS33180
uniprot id: A0A1D7YPL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1904616:BFF78 RS14150
gene id: 1904616:BFF78_RS14150
uniprot id: A0A1D7Y8T8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41820
gene id: 1904616:BFF78_RS41820
uniprot id: A0A1D7YMB9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1904616:BFF78 RS37565
gene id: 1904616:BFF78_RS37565
uniprot id: A0A1D7YK78
names: Similarity
messages: Belongs to the asparagine synthetase family.

1904616:BFF78 RS35850
gene id: 1904616:BFF78_RS35850
uniprot id: A0A1D7YJK0
names: Subunit
messages: Homodimer.

1904616:BFF78 RS17225
gene id: 1904616:BFF78_RS17225
uniprot id: A0A1D7YAC2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS33200
gene id: 1904616:BFF78_RS33200
uniprot id: A0A1D7YPH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1904616:BFF78 RS11220
gene id: 1904616:BFF78_RS11220
uniprot id: A0A1D7Y7D8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1904616:BFF78 RS30240
gene id: 1904616:BFF78_RS30240
uniprot id: A0A1D7YGN8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS32150
gene id: 1904616:BFF78_RS32150
uniprot id: A0A1D7YHS3
names: Similarity
messages: Belongs to the asp23 family.

1904616:BFF78 RS22900
gene id: 1904616:BFF78_RS22900
uniprot id: A0A1D7YDA3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1904616:BFF78 RS09015
gene id: 1904616:BFF78_RS09015
uniprot id: A0A1D7Y6C2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41275
gene id: 1904616:BFF78_RS41275
uniprot id: A0A1D7YM63
names: Similarity
messages: Belongs to the barstar family.

1904616:BFF78 RS16505
gene id: 1904616:BFF78_RS16505
uniprot id: A0A1D7YA69
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS02145
gene id: 1904616:BFF78_RS02145
uniprot id: A0A1D7Y371
names: Similarity
messages: Belongs to the UPF0098 family.

1904616:BFF78 RS14810
gene id: 1904616:BFF78_RS14810
uniprot id: A0A1D7Y9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1904616:BFF78 RS26795
gene id: 1904616:BFF78_RS26795
uniprot id: A0A1D7YFS5
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1904616:BFF78 RS40930
gene id: 1904616:BFF78_RS40930
uniprot id: A0A1D7YLX5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1904616:BFF78 RS39815
gene id: 1904616:BFF78_RS39815
uniprot id: A0A1D7YLD6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS09230
gene id: 1904616:BFF78_RS09230
uniprot id: A0A1D7Y6R2
names: Similarity
messages: Belongs to the CdaR family.

1904616:BFF78 RS03960
gene id: 1904616:BFF78_RS03960
uniprot id: A0A1D7Y4N3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1904616:BFF78 RS34620
gene id: 1904616:BFF78_RS34620
uniprot id: A0A1D7YIV3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS12555
gene id: 1904616:BFF78_RS12555
uniprot id: A0A1D7Y8H8
names: Similarity
messages: Belongs to the peptidase M16 family.

1904616:BFF78 RS28075
gene id: 1904616:BFF78_RS28075
uniprot id: A0A1D7YFK3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1904616:BFF78 RS19170
gene id: 1904616:BFF78_RS19170
uniprot id: A0A1D7YBG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1904616:BFF78 RS02705
gene id: 1904616:BFF78_RS02705
uniprot id: A0A1D7Y3I5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1904616:BFF78 RS12430
gene id: 1904616:BFF78_RS12430
uniprot id: A0A1D7Y852
names: Similarity
messages: Belongs to the FPG family.

1904616:BFF78 RS33800
gene id: 1904616:BFF78_RS33800
uniprot id: A0A1D7YIG0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1904616:BFF78 RS05350
gene id: 1904616:BFF78_RS05350
uniprot id: A0A1D7YND2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1904616:BFF78 RS30300
gene id: 1904616:BFF78_RS30300
uniprot id: A0A1D7YGW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1904616:BFF78 RS23940
gene id: 1904616:BFF78_RS23940
uniprot id: A0A1D7YEE0
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1904616:BFF78 RS14415
gene id: 1904616:BFF78_RS14415
uniprot id: A0A1D7Y9B6
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS34210
gene id: 1904616:BFF78_RS34210
uniprot id: A0A1D7YPG3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS37385
gene id: 1904616:BFF78_RS37385
uniprot id: A0A1D7YQ46
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1904616:BFF78 RS12195
gene id: 1904616:BFF78_RS12195
uniprot id: A0A1D7Y8B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS09565
gene id: 1904616:BFF78_RS09565
uniprot id: A0A1D7Y722
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1904616:BFF78 RS32045
gene id: 1904616:BFF78_RS32045
uniprot id: A0A1D7YHQ0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1904616:BFF78 RS03675
gene id: 1904616:BFF78_RS03675
uniprot id: A0A1D7Y3Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1904616:BFF78 RS34715
gene id: 1904616:BFF78_RS34715
uniprot id: A0A1D7YJ13
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1904616:BFF78 RS10395
gene id: 1904616:BFF78_RS10395
uniprot id: A0A1D7Y731
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1904616:BFF78 RS40205
gene id: 1904616:BFF78_RS40205
uniprot id: A0A1D7YM48
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1904616:BFF78 RS04905
gene id: 1904616:BFF78_RS04905
uniprot id: A0A1D7Y4F6
names: Similarity
messages: Belongs to the CapA family.

1904616:BFF78 RS34985
gene id: 1904616:BFF78_RS34985
uniprot id: A0A1D7YJ69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS23350
gene id: 1904616:BFF78_RS23350
uniprot id: A0A1D7YDI6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1904616:BFF78 RS36120
gene id: 1904616:BFF78_RS36120
uniprot id: A0A1D7YPN0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS12795
gene id: 1904616:BFF78_RS12795
uniprot id: A0A1D7Y8L4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1904616:BFF78 RS08970
gene id: 1904616:BFF78_RS08970
uniprot id: A0A1D7Y6T2
names: Similarity
messages: Belongs to the peptidase S9C family.

1904616:BFF78 RS26130
gene id: 1904616:BFF78_RS26130
uniprot id: A0A1D7YEM5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS28235
gene id: 1904616:BFF78_RS28235
uniprot id: A0A1D7YFY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1904616:BFF78 RS07770
gene id: 1904616:BFF78_RS07770
uniprot id: A0A1D7Y5T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1904616:BFF78 RS24405
gene id: 1904616:BFF78_RS24405
uniprot id: A0A1D7YE01
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1904616:BFF78 RS41460
gene id: 1904616:BFF78_RS41460
uniprot id: A0A1D7YQ33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1904616:BFF78 RS16145
gene id: 1904616:BFF78_RS16145
uniprot id: A0A1D7Y9U1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS08825
gene id: 1904616:BFF78_RS08825
uniprot id: A0A1D7Y6B1
names: Similarity
messages: Belongs to the peptidase C56 family.

1904616:BFF78 RS02345
gene id: 1904616:BFF78_RS02345
uniprot id: A0A1D7Y3B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1904616:BFF78 RS03010
gene id: 1904616:BFF78_RS03010
uniprot id: A0A1D7Y477
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1904616:BFF78 RS27235
gene id: 1904616:BFF78_RS27235
uniprot id: A0A1D7YFG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS17465
gene id: 1904616:BFF78_RS17465
uniprot id: A0A1D7YAT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1904616:BFF78 RS21905
gene id: 1904616:BFF78_RS21905
uniprot id: A0A1D7YCM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

1904616:BFF78 RS15115
gene id: 1904616:BFF78_RS15115
uniprot id: A0A1D7YA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS14620
gene id: 1904616:BFF78_RS14620
uniprot id: A0A1D7Y986
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS30645
gene id: 1904616:BFF78_RS30645
uniprot id: A0A1D7YH27
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS05685
gene id: 1904616:BFF78_RS05685
uniprot id: A0A1D7Y4U0
names: Similarity
messages: Belongs to the AAA ATPase family.

1904616:BFF78 RS19990
gene id: 1904616:BFF78_RS19990
uniprot id: A0A1D7YCF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1904616:BFF78 RS38135
gene id: 1904616:BFF78_RS38135
uniprot id: A0A1D7YKN5
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1904616:BFF78 RS30960
gene id: 1904616:BFF78_RS30960
uniprot id: A0A1D7YGZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS27075
gene id: 1904616:BFF78_RS27075
uniprot id: A0A1D7YFX4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1904616:BFF78 RS05015
gene id: 1904616:BFF78_RS05015
uniprot id: A0A1D7Y4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS11960
gene id: 1904616:BFF78_RS11960
uniprot id: A0A1D7Y7W4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1904616:BFF78 RS23850
gene id: 1904616:BFF78_RS23850
uniprot id: A0A1D7YDK1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS08605
gene id: 1904616:BFF78_RS08605
uniprot id: A0A1D7Y677
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1904616:BFF78 RS30465
gene id: 1904616:BFF78_RS30465
uniprot id: A0A1D7YPJ2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS04475
gene id: 1904616:BFF78_RS04475
uniprot id: A0A1D7Y490
names: Similarity
messages: Belongs to the universal stress protein A family.

1904616:BFF78 RS13030
gene id: 1904616:BFF78_RS13030
uniprot id: A0A1D7Y8Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1904616:BFF78 RS26210
gene id: 1904616:BFF78_RS26210
uniprot id: A0A1D7YEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS31480
gene id: 1904616:BFF78_RS31480
uniprot id: A0A1D7YPH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1904616:BFF78 RS20270
gene id: 1904616:BFF78_RS20270
uniprot id: A0A1D7YBU0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1904616:BFF78 RS29455
gene id: 1904616:BFF78_RS29455
uniprot id: A0A1D7YG74
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1904616:BFF78 RS30820
gene id: 1904616:BFF78_RS30820
uniprot id: A0A1D7YH45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1904616:BFF78 RS08730
gene id: 1904616:BFF78_RS08730
uniprot id: A0A1D7Y6W7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1904616:BFF78 RS18360
gene id: 1904616:BFF78_RS18360
uniprot id: A0A1D7YAW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1904616:BFF78 RS31525
gene id: 1904616:BFF78_RS31525
uniprot id: A0A1D7YH91
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1904616:BFF78 RS26860
gene id: 1904616:BFF78_RS26860
uniprot id: A0A1D7YF55
names: Similarity
messages: Belongs to the TPP enzyme family.

1904616:BFF78 RS37515
gene id: 1904616:BFF78_RS37515
uniprot id: A0A1D7YK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1904616:BFF78 RS22075
gene id: 1904616:BFF78_RS22075
uniprot id: A0A1D7YCQ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS09665
gene id: 1904616:BFF78_RS09665
uniprot id: A0A1D7Y7D1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS21200
gene id: 1904616:BFF78_RS21200
uniprot id: A0A1D7YC99
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1904616:BFF78 RS23035
gene id: 1904616:BFF78_RS23035
uniprot id: A0A1D7YDH0
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS31575
gene id: 1904616:BFF78_RS31575
uniprot id: A0A1D7YPV2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS19855
gene id: 1904616:BFF78_RS19855
uniprot id: A0A1D7YBY9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS47800
gene id: 1904616:BFF78_RS47800
uniprot id: A0A1D7Y3P2
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS34905
gene id: 1904616:BFF78_RS34905
uniprot id: A0A1D7YJ54
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS07620
gene id: 1904616:BFF78_RS07620
uniprot id: A0A1D7Y5Z0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1904616:BFF78 RS16855
gene id: 1904616:BFF78_RS16855
uniprot id: A0A1D7YAL1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1904616:BFF78 RS25850
gene id: 1904616:BFF78_RS25850
uniprot id: A0A1D7YEH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS13705
gene id: 1904616:BFF78_RS13705
uniprot id: A0A1D7Y8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS04600
gene id: 1904616:BFF78_RS04600
uniprot id: A0A1D7Y4F4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS39025
gene id: 1904616:BFF78_RS39025
uniprot id: A0A1D7YKY2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41395
gene id: 1904616:BFF78_RS41395
uniprot id: A0A1D7YMP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

1904616:BFF78 RS24490
gene id: 1904616:BFF78_RS24490
uniprot id: A0A1D7YE30
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS01715
gene id: 1904616:BFF78_RS01715
uniprot id: A0A1D7Y322
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS40555
gene id: 1904616:BFF78_RS40555
uniprot id: A0A1D7YLP1
names: Similarity
messages: Belongs to the CapA family.

1904616:BFF78 RS02680
gene id: 1904616:BFF78_RS02680
uniprot id: A0A1D7Y3F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS12970
gene id: 1904616:BFF78_RS12970
uniprot id: A0A1D7Y879
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1904616:BFF78 RS25660
gene id: 1904616:BFF78_RS25660
uniprot id: A0A1D7YEL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS10730
gene id: 1904616:BFF78_RS10730
uniprot id: A0A1D7YNN1
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.

1904616:BFF78 RS33055
gene id: 1904616:BFF78_RS33055
uniprot id: A0A1D7YI79
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1904616:BFF78 RS30985
gene id: 1904616:BFF78_RS30985
uniprot id: A0A1D7YH90
names: Similarity
messages: Belongs to the TrpC family.

1904616:BFF78 RS14875
gene id: 1904616:BFF78_RS14875
uniprot id: A0A1D7Y9L6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1904616:BFF78 RS22905
gene id: 1904616:BFF78_RS22905
uniprot id: A0A1D7YD37
names: Similarity
messages: Belongs to the Fur family.

1904616:BFF78 RS17535
gene id: 1904616:BFF78_RS17535
uniprot id: A0A1D7YAH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1904616:BFF78 RS25340
gene id: 1904616:BFF78_RS25340
uniprot id: A0A1D7YE91
names: Similarity
messages: Belongs to the PGI/PMI family.

1904616:BFF78 RS20160
gene id: 1904616:BFF78_RS20160
uniprot id: A0A1D7YBR7
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS14250
gene id: 1904616:BFF78_RS14250
uniprot id: A0A1D7Y8V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1904616:BFF78 RS22470
gene id: 1904616:BFF78_RS22470
uniprot id: A0A1D7YDP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1904616:BFF78 RS13595
gene id: 1904616:BFF78_RS13595
uniprot id: A0A1D7Y8X4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1904616:BFF78 RS17440
gene id: 1904616:BFF78_RS17440
uniprot id: A0A1D7YB96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1904616:BFF78 RS27535
gene id: 1904616:BFF78_RS27535
uniprot id: A0A1D7YP90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1904616:BFF78 RS24165
gene id: 1904616:BFF78_RS24165
uniprot id: A0A1D7YDQ6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1904616:BFF78 RS12515
gene id: 1904616:BFF78_RS12515
uniprot id: A0A1D7Y825
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1904616:BFF78 RS32710
gene id: 1904616:BFF78_RS32710
uniprot id: A0A1D7YI37
names: Similarity
messages: Belongs to the peptidase S1 family.

1904616:BFF78 RS39855
gene id: 1904616:BFF78_RS39855
uniprot id: A0A1D7YLZ2
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1904616:BFF78 RS08675
gene id: 1904616:BFF78_RS08675
uniprot id: A0A1D7Y676
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1904616:BFF78 RS06490
gene id: 1904616:BFF78_RS06490
uniprot id: A0A1D7Y583
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1904616:BFF78 RS26560
gene id: 1904616:BFF78_RS26560
uniprot id: A0A1D7YF35
names: Similarity
messages: Belongs to the IucA/IucC family.

1904616:BFF78 RS25625
gene id: 1904616:BFF78_RS25625
uniprot id: A0A1D7YER3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1904616:BFF78 RS39270
gene id: 1904616:BFF78_RS39270
uniprot id: A0A1D7YLP5
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS27705
gene id: 1904616:BFF78_RS27705
uniprot id: A0A1D7YFJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1904616:BFF78 RS10345
gene id: 1904616:BFF78_RS10345
uniprot id: A0A1D7Y718
names: Similarity
messages: Belongs to the TPP enzyme family.

1904616:BFF78 RS24775
gene id: 1904616:BFF78_RS24775
uniprot id: A0A1D7YER7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21535
gene id: 1904616:BFF78_RS21535
uniprot id: A0A1D7YCN2
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1904616:BFF78 RS17475
gene id: 1904616:BFF78_RS17475
uniprot id: A0A1D7YAW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1904616:BFF78 RS10505
gene id: 1904616:BFF78_RS10505
uniprot id: A0A1D7Y7H3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS07080
gene id: 1904616:BFF78_RS07080
uniprot id: A0A1D7Y5G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS34260
gene id: 1904616:BFF78_RS34260
uniprot id: A0A1D7YIN8
names: Similarity
messages: Belongs to the barstar family.

1904616:BFF78 RS28615
gene id: 1904616:BFF78_RS28615
uniprot id: A0A1D7YFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS33650
gene id: 1904616:BFF78_RS33650
uniprot id: A0A1D7YII8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1904616:BFF78 RS29555
gene id: 1904616:BFF78_RS29555
uniprot id: A0A1D7YGI4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1904616:BFF78 RS13575
gene id: 1904616:BFF78_RS13575
uniprot id: A0A1D7Y8Q5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS32060
gene id: 1904616:BFF78_RS32060
uniprot id: A0A1D7YPJ8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1904616:BFF78 RS10955
gene id: 1904616:BFF78_RS10955
uniprot id: A0A1D7Y7M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1904616:BFF78 RS34665
gene id: 1904616:BFF78_RS34665
uniprot id: A0A1D7YJ11
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS11685
gene id: 1904616:BFF78_RS11685
uniprot id: A0A1D7YNF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1904616:BFF78 RS32685
gene id: 1904616:BFF78_RS32685
uniprot id: A0A1D7YIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1904616:BFF78 RS28055
gene id: 1904616:BFF78_RS28055
uniprot id: A0A1D7YP75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1904616:BFF78 RS16260
gene id: 1904616:BFF78_RS16260
uniprot id: A0A1D7YA87
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1904616:BFF78 RS30020
gene id: 1904616:BFF78_RS30020
uniprot id: A0A1D7YGR7
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1904616:BFF78 RS21345
gene id: 1904616:BFF78_RS21345
uniprot id: A0A1D7YCD2
names: Similarity
messages: Belongs to the FemABX family.

1904616:BFF78 RS06890
gene id: 1904616:BFF78_RS06890
uniprot id: A0A1D7Y5I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1904616:BFF78 RS34730
gene id: 1904616:BFF78_RS34730
uniprot id: A0A1D7YJ21
names: Similarity
messages: Belongs to the UPF0749 family.

1904616:BFF78 RS03325
gene id: 1904616:BFF78_RS03325
uniprot id: A0A1D7Y3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS05835
gene id: 1904616:BFF78_RS05835
uniprot id: A0A1D7Y4W8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1904616:BFF78 RS06360
gene id: 1904616:BFF78_RS06360
uniprot id: A0A1D7YNF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm

1904616:BFF78 RS18115
gene id: 1904616:BFF78_RS18115
uniprot id: A0A1D7YAR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1904616:BFF78 RS33625
gene id: 1904616:BFF78_RS33625
uniprot id: A0A1D7YPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1904616:BFF78 RS16245
gene id: 1904616:BFF78_RS16245
uniprot id: A0A1D7YA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS17445
gene id: 1904616:BFF78_RS17445
uniprot id: A0A1D7YAW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1904616:BFF78 RS01175
gene id: 1904616:BFF78_RS01175
uniprot id: A0A1D7Y2R1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1904616:BFF78 RS26265
gene id: 1904616:BFF78_RS26265
uniprot id: A0A1D7YEZ8
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS13190
gene id: 1904616:BFF78_RS13190
uniprot id: A0A1D7Y8I7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1904616:BFF78 RS34065
gene id: 1904616:BFF78_RS34065
uniprot id: A0A1D7YJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1904616:BFF78 RS24620
gene id: 1904616:BFF78_RS24620
uniprot id: A0A1D7YE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1904616:BFF78 RS04045
gene id: 1904616:BFF78_RS04045
uniprot id: A0A1D7Y428
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS35730
gene id: 1904616:BFF78_RS35730
uniprot id: A0A1D7YJE6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS32680
gene id: 1904616:BFF78_RS32680
uniprot id: A0A1D7YHW1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS30780
gene id: 1904616:BFF78_RS30780
uniprot id: A0A1D7YH47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1904616:BFF78 RS22665
gene id: 1904616:BFF78_RS22665
uniprot id: A0A1D7YDS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1904616:BFF78 RS25805
gene id: 1904616:BFF78_RS25805
uniprot id: A0A1D7YEG5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS30525
gene id: 1904616:BFF78_RS30525
uniprot id: A0A1D7YH11
names: Similarity
messages: Belongs to the arsA ATPase family.

1904616:BFF78 RS18165
gene id: 1904616:BFF78_RS18165
uniprot id: A0A1D7YAZ5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS12075
gene id: 1904616:BFF78_RS12075
uniprot id: A0A1D7Y807
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1904616:BFF78 RS16035
gene id: 1904616:BFF78_RS16035
uniprot id: A0A1D7YA65
names: Similarity
messages: Belongs to the GSP E family.

1904616:BFF78 RS26885
gene id: 1904616:BFF78_RS26885
uniprot id: A0A1D7YFA3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS28025
gene id: 1904616:BFF78_RS28025
uniprot id: A0A1D7YFU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1904616:BFF78 RS00445
gene id: 1904616:BFF78_RS00445
uniprot id: A0A1D7Y2E8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

1904616:BFF78 RS33080
gene id: 1904616:BFF78_RS33080
uniprot id: A0A1D7YI88
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS27700
gene id: 1904616:BFF78_RS27700
uniprot id: A0A1D7YFP3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1904616:BFF78 RS13915
gene id: 1904616:BFF78_RS13915
uniprot id: A0A1D7Y930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1904616:BFF78 RS07090
gene id: 1904616:BFF78_RS07090
uniprot id: A0A1D7Y5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1904616:BFF78 RS05330
gene id: 1904616:BFF78_RS05330
uniprot id: A0A1D7Y541
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1904616:BFF78 RS09690
gene id: 1904616:BFF78_RS09690
uniprot id: A0A1D7Y6Q8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS29630
gene id: 1904616:BFF78_RS29630
uniprot id: A0A1D7YGM8
names: Similarity
messages: Belongs to the UPF0246 family.

1904616:BFF78 RS37065
gene id: 1904616:BFF78_RS37065
uniprot id: A0A1D7YPQ8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1904616:BFF78 RS13360
gene id: 1904616:BFF78_RS13360
uniprot id: A0A1D7Y8F3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1904616:BFF78 RS22765
gene id: 1904616:BFF78_RS22765
uniprot id: A0A1D7YD10
names: Similarity
messages: Belongs to the AAA ATPase family.

1904616:BFF78 RS11965
gene id: 1904616:BFF78_RS11965
uniprot id: A0A1D7Y7T8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1904616:BFF78 RS14840
gene id: 1904616:BFF78_RS14840
uniprot id: A0A1D7YA10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1904616:BFF78 RS12955
gene id: 1904616:BFF78_RS12955
uniprot id: A0A1D7Y8A0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1904616:BFF78 RS15220
gene id: 1904616:BFF78_RS15220
uniprot id: A0A1D7Y9S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1904616:BFF78 RS40640
gene id: 1904616:BFF78_RS40640
uniprot id: A0A1D7YLQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS36540
gene id: 1904616:BFF78_RS36540
uniprot id: A0A1D7YJV9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1904616:BFF78 RS32055
gene id: 1904616:BFF78_RS32055
uniprot id: A0A1D7YHR3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS25725
gene id: 1904616:BFF78_RS25725
uniprot id: A0A1D7YEM4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1904616:BFF78 RS03260
gene id: 1904616:BFF78_RS03260
uniprot id: A0A1D7Y4C2
names: Similarity
messages: Belongs to the ComB family.

1904616:BFF78 RS32430
gene id: 1904616:BFF78_RS32430
uniprot id: A0A1D7YHS0
names: Similarity
messages: Belongs to the UPF0098 family.

1904616:BFF78 RS18065
gene id: 1904616:BFF78_RS18065
uniprot id: A0A1D7YB63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS05055
gene id: 1904616:BFF78_RS05055
uniprot id: A0A1D7Y4J0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1904616:BFF78 RS31245
gene id: 1904616:BFF78_RS31245
uniprot id: A0A1D7YHC7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS25880
gene id: 1904616:BFF78_RS25880
uniprot id: A0A1D7YEP8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS18915
gene id: 1904616:BFF78_RS18915
uniprot id: A0A1D7YBY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1904616:BFF78 RS34455
gene id: 1904616:BFF78_RS34455
uniprot id: A0A1D7YIR8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS37920
gene id: 1904616:BFF78_RS37920
uniprot id: A0A1D7YKJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1904616:BFF78 RS49540
gene id: 1904616:BFF78_RS49540
uniprot id: A0A1D7YGM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1904616:BFF78 RS10540
gene id: 1904616:BFF78_RS10540
uniprot id: A0A1D7Y717
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS30710
gene id: 1904616:BFF78_RS30710
uniprot id: A0A1D7YGW5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1904616:BFF78 RS11235
gene id: 1904616:BFF78_RS11235
uniprot id: A0A1D7Y7J6
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1904616:BFF78 RS17415
gene id: 1904616:BFF78_RS17415
uniprot id: A0A1D7YAF1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1904616:BFF78 RS35595
gene id: 1904616:BFF78_RS35595
uniprot id: A0A1D7YJB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1904616:BFF78 RS15280
gene id: 1904616:BFF78_RS15280
uniprot id: A0A1D7Y9T6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1904616:BFF78 RS31125
gene id: 1904616:BFF78_RS31125
uniprot id: A0A1D7YH94
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1904616:BFF78 RS01020
gene id: 1904616:BFF78_RS01020
uniprot id: A0A1D7Y329
names: Similarity
messages: Belongs to the peptidase S33 family.

1904616:BFF78 RS05605
gene id: 1904616:BFF78_RS05605
uniprot id: A0A1D7Y4S2
names: Similarity
messages: Belongs to the FGGY kinase family.

1904616:BFF78 RS29270
gene id: 1904616:BFF78_RS29270
uniprot id: A0A1D7YGD8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS05880
gene id: 1904616:BFF78_RS05880
uniprot id: A0A1D7Y5L0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1904616:BFF78 RS16175
gene id: 1904616:BFF78_RS16175
uniprot id: A0A1D7Y9Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1904616:BFF78 RS41380
gene id: 1904616:BFF78_RS41380
uniprot id: A0A1D7YM72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS05935
gene id: 1904616:BFF78_RS05935
uniprot id: A0A1D7Y5C6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1904616:BFF78 RS22330
gene id: 1904616:BFF78_RS22330
uniprot id: A0A1D7YCT6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1904616:BFF78 RS35820
gene id: 1904616:BFF78_RS35820
uniprot id: A0A1D7YJF9
names: Similarity
messages: Belongs to the thioesterase family.

1904616:BFF78 RS18845
gene id: 1904616:BFF78_RS18845
uniprot id: A0A1D7YBI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1904616:BFF78 RS36620
gene id: 1904616:BFF78_RS36620
uniprot id: A0A1D7YJY2
names: Similarity
messages: Belongs to the UPF0047 family.

1904616:BFF78 RS12365
gene id: 1904616:BFF78_RS12365
uniprot id: A0A1D7Y855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS25310
gene id: 1904616:BFF78_RS25310
uniprot id: A0A1D7YEE1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1904616:BFF78 RS30415
gene id: 1904616:BFF78_RS30415
uniprot id: A0A1D7YGS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1904616:BFF78 RS18645
gene id: 1904616:BFF78_RS18645
uniprot id: A0A1D7YBC9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1904616:BFF78 RS16150
gene id: 1904616:BFF78_RS16150
uniprot id: A0A1D7YA92
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS38815
gene id: 1904616:BFF78_RS38815
uniprot id: A0A1D7YLG8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS24440
gene id: 1904616:BFF78_RS24440
uniprot id: A0A1D7YDT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1904616:BFF78 RS41095
gene id: 1904616:BFF78_RS41095
uniprot id: A0A1D7YM24
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS41435
gene id: 1904616:BFF78_RS41435
uniprot id: A0A1D7YM82
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1904616:BFF78 RS27685
gene id: 1904616:BFF78_RS27685
uniprot id: A0A1D7YFD8
names: Similarity
messages: Belongs to the peptidase M1 family.

1904616:BFF78 RS23320
gene id: 1904616:BFF78_RS23320
uniprot id: A0A1D7YDL9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1904616:BFF78 RS09765
gene id: 1904616:BFF78_RS09765
uniprot id: A0A1D7Y6P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1904616:BFF78 RS10830
gene id: 1904616:BFF78_RS10830
uniprot id: A0A1D7Y7B0
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS37135
gene id: 1904616:BFF78_RS37135
uniprot id: A0A1D7YPP7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS13095
gene id: 1904616:BFF78_RS13095
uniprot id: A0A1D7Y8C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1904616:BFF78 RS35305
gene id: 1904616:BFF78_RS35305
uniprot id: A0A1D7YQ11
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1904616:BFF78 RS02105
gene id: 1904616:BFF78_RS02105
uniprot id: A0A1D7Y352
names: Similarity
messages: Belongs to the peptidase S1 family.

1904616:BFF78 RS05845
gene id: 1904616:BFF78_RS05845
uniprot id: A0A1D7Y4X3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS37560
gene id: 1904616:BFF78_RS37560
uniprot id: A0A1D7YKF5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS17545
gene id: 1904616:BFF78_RS17545
uniprot id: A0A1D7YBB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1904616:BFF78 RS15830
gene id: 1904616:BFF78_RS15830
uniprot id: A0A1D7Y9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1904616:BFF78 RS26600
gene id: 1904616:BFF78_RS26600
uniprot id: A0A1D7YEU9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1904616:BFF78 RS19360
gene id: 1904616:BFF78_RS19360
uniprot id: A0A1D7YBD5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS06220
gene id: 1904616:BFF78_RS06220
uniprot id: A0A1D7Y504
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1904616:BFF78 RS00355
gene id: 1904616:BFF78_RS00355
uniprot id: A0A1D7Y2C2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1904616:BFF78 RS14460
gene id: 1904616:BFF78_RS14460
uniprot id: A0A1D7Y959
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS14030
gene id: 1904616:BFF78_RS14030
uniprot id: A0A1D7Y8S4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1904616:BFF78 RS33645
gene id: 1904616:BFF78_RS33645
uniprot id: A0A1D7YJ44
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1904616:BFF78 RS40410
gene id: 1904616:BFF78_RS40410
uniprot id: A0A1D7YLS7
names: Similarity
messages: Belongs to the pirin family.

1904616:BFF78 RS11990
gene id: 1904616:BFF78_RS11990
uniprot id: A0A1D7Y7S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1904616:BFF78 RS15055
gene id: 1904616:BFF78_RS15055
uniprot id: A0A1D7Y9A9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1904616:BFF78 RS04570
gene id: 1904616:BFF78_RS04570
uniprot id: A0A1D7Y4A9
names: Subunit
messages: Homodimer.

1904616:BFF78 RS07565
gene id: 1904616:BFF78_RS07565
uniprot id: A0A1D7Y5N1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS35470
gene id: 1904616:BFF78_RS35470
uniprot id: A0A1D7YPK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS23045
gene id: 1904616:BFF78_RS23045
uniprot id: A0A1D7YD52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1904616:BFF78 RS31155
gene id: 1904616:BFF78_RS31155
uniprot id: A0A1D7YHT8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS37825
gene id: 1904616:BFF78_RS37825
uniprot id: A0A1D7YL17
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

1904616:BFF78 RS33940
gene id: 1904616:BFF78_RS33940
uniprot id: A0A1D7YIM5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1904616:BFF78 RS22240
gene id: 1904616:BFF78_RS22240
uniprot id: A0A1D7YCS6
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1904616:BFF78 RS30995
gene id: 1904616:BFF78_RS30995
uniprot id: A0A1D7YH74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1904616:BFF78 RS12755
gene id: 1904616:BFF78_RS12755
uniprot id: A0A1D7Y867
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS37045
gene id: 1904616:BFF78_RS37045
uniprot id: A0A1D7YK53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1904616:BFF78 RS04040
gene id: 1904616:BFF78_RS04040
uniprot id: A0A1D7Y447
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS31050
gene id: 1904616:BFF78_RS31050
uniprot id: A0A1D7YHA3
names: Similarity
messages: Belongs to the glutamate synthase family.

1904616:BFF78 RS34115
gene id: 1904616:BFF78_RS34115
uniprot id: A0A1D7YIK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1904616:BFF78 RS34515
gene id: 1904616:BFF78_RS34515
uniprot id: A0A1D7YIT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1904616:BFF78 RS33425
gene id: 1904616:BFF78_RS33425
uniprot id: A0A1D7YIE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS25025
gene id: 1904616:BFF78_RS25025
uniprot id: A0A1D7YEB6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1904616:BFF78 RS20675
gene id: 1904616:BFF78_RS20675
uniprot id: A0A1D7YC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1904616:BFF78 RS23355
gene id: 1904616:BFF78_RS23355
uniprot id: A0A1D7YDB7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1904616:BFF78 RS38835
gene id: 1904616:BFF78_RS38835
uniprot id: A0A1D7YL26
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Monomer.

1904616:BFF78 RS29725
gene id: 1904616:BFF78_RS29725
uniprot id: A0A1D7YGM9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS26025
gene id: 1904616:BFF78_RS26025
uniprot id: A0A1D7YEW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1904616:BFF78 RS02075
gene id: 1904616:BFF78_RS02075
uniprot id: A0A1D7Y361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS14120
gene id: 1904616:BFF78_RS14120
uniprot id: A0A1D7Y9L3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1904616:BFF78 RS23095
gene id: 1904616:BFF78_RS23095
uniprot id: A0A1D7YD69
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS26530
gene id: 1904616:BFF78_RS26530
uniprot id: A0A1D7YEZ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS16745
gene id: 1904616:BFF78_RS16745
uniprot id: A0A1D7YA38
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS21100
gene id: 1904616:BFF78_RS21100
uniprot id: A0A1D7YCN5
names: Similarity
messages: Belongs to the UPF0749 family.

1904616:BFF78 RS30760
gene id: 1904616:BFF78_RS30760
uniprot id: A0A1D7YPG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

1904616:BFF78 RS37980
gene id: 1904616:BFF78_RS37980
uniprot id: A0A1D7YKK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1904616:BFF78 RS12945
gene id: 1904616:BFF78_RS12945
uniprot id: A0A1D7Y898
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS29290
gene id: 1904616:BFF78_RS29290
uniprot id: A0A1D7YG50
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1904616:BFF78 RS01855
gene id: 1904616:BFF78_RS01855
uniprot id: A0A1D7Y331
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS28165
gene id: 1904616:BFF78_RS28165
uniprot id: A0A1D7YFK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1904616:BFF78 RS25470
gene id: 1904616:BFF78_RS25470
uniprot id: A0A1D7YEB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1904616:BFF78 RS05140
gene id: 1904616:BFF78_RS05140
uniprot id: A0A1D7Y5A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS07075
gene id: 1904616:BFF78_RS07075
uniprot id: A0A1D7Y5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS38730
gene id: 1904616:BFF78_RS38730
uniprot id: A0A1D7YKT0
names: Similarity
messages: Belongs to the tannase family.

1904616:BFF78 RS22335
gene id: 1904616:BFF78_RS22335
uniprot id: A0A1D7YDM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1904616:BFF78 RS32720
gene id: 1904616:BFF78_RS32720
uniprot id: A0A1D7YHX3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1904616:BFF78 RS39900
gene id: 1904616:BFF78_RS39900
uniprot id: A0A1D7YLC6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS02800
gene id: 1904616:BFF78_RS02800
uniprot id: A0A1D7Y3V6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS19605
gene id: 1904616:BFF78_RS19605
uniprot id: A0A1D7YBH2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1904616:BFF78 RS11630
gene id: 1904616:BFF78_RS11630
uniprot id: A0A1D7Y7N5
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1904616:BFF78 RS33965
gene id: 1904616:BFF78_RS33965
uniprot id: A0A1D7YIP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1904616:BFF78 RS03030
gene id: 1904616:BFF78_RS03030
uniprot id: A0A1D7Y3N0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1904616:BFF78 RS16770
gene id: 1904616:BFF78_RS16770
uniprot id: A0A1D7YA36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Belongs to the peptidase S8 family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS20860
gene id: 1904616:BFF78_RS20860
uniprot id: A0A1D7YCX3
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS38340
gene id: 1904616:BFF78_RS38340
uniprot id: A0A1D7YKL0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1904616:BFF78 RS31495
gene id: 1904616:BFF78_RS31495
uniprot id: A0A1D7YPC5
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1904616:BFF78 RS04730
gene id: 1904616:BFF78_RS04730
uniprot id: A0A1D7Y4F9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1904616:BFF78 RS26180
gene id: 1904616:BFF78_RS26180
uniprot id: A0A1D7YEN6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS05535
gene id: 1904616:BFF78_RS05535
uniprot id: A0A1D7Y569
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS40845
gene id: 1904616:BFF78_RS40845
uniprot id: A0A1D7YLY4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1904616:BFF78 RS09235
gene id: 1904616:BFF78_RS09235
uniprot id: A0A1D7Y6F7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS35550
gene id: 1904616:BFF78_RS35550
uniprot id: A0A1D7YJG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS16445
gene id: 1904616:BFF78_RS16445
uniprot id: A0A1D7YA58
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1904616:BFF78 RS05365
gene id: 1904616:BFF78_RS05365
uniprot id: A0A1D7Y4Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1904616:BFF78 RS21465
gene id: 1904616:BFF78_RS21465
uniprot id: A0A1D7YCE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1904616:BFF78 RS32370
gene id: 1904616:BFF78_RS32370
uniprot id: A0A1D7YHQ7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS33855
gene id: 1904616:BFF78_RS33855
uniprot id: A0A1D7YIG4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS04525
gene id: 1904616:BFF78_RS04525
uniprot id: A0A1D7Y4D2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS33985
gene id: 1904616:BFF78_RS33985
uniprot id: A0A1D7YII9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1904616:BFF78 RS30620
gene id: 1904616:BFF78_RS30620
uniprot id: A0A1D7YHK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1904616:BFF78 RS11065
gene id: 1904616:BFF78_RS11065
uniprot id: A0A1D7Y7D0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS30190
gene id: 1904616:BFF78_RS30190
uniprot id: A0A1D7YGM2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS03510
gene id: 1904616:BFF78_RS03510
uniprot id: A0A1D7Y3U5
names: Similarity
messages: Belongs to the group II decarboxylase family.

1904616:BFF78 RS07515
gene id: 1904616:BFF78_RS07515
uniprot id: A0A1D7Y5M8
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

1904616:BFF78 RS15515
gene id: 1904616:BFF78_RS15515
uniprot id: A0A1D7YAD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS04520
gene id: 1904616:BFF78_RS04520
uniprot id: A0A1D7Y498
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS37630
gene id: 1904616:BFF78_RS37630
uniprot id: A0A1D7YKE3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS23005
gene id: 1904616:BFF78_RS23005
uniprot id: A0A1D7YDJ2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1904616:BFF78 RS05590
gene id: 1904616:BFF78_RS05590
uniprot id: A0A1D7YMS6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1904616:BFF78 RS03830
gene id: 1904616:BFF78_RS03830
uniprot id: A0A1D7Y4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

1904616:BFF78 RS25570
gene id: 1904616:BFF78_RS25570
uniprot id: A0A1D7YEQ3
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1904616:BFF78 RS23220
gene id: 1904616:BFF78_RS23220
uniprot id: A0A1D7YD89
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1904616:BFF78 RS16515
gene id: 1904616:BFF78_RS16515
uniprot id: A0A1D7YAC5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS31840
gene id: 1904616:BFF78_RS31840
uniprot id: A0A1D7YHG3
names: Similarity
messages: Belongs to the DapA family.

1904616:BFF78 RS03375
gene id: 1904616:BFF78_RS03375
uniprot id: A0A1D7Y4E3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1904616:BFF78 RS29750
gene id: 1904616:BFF78_RS29750
uniprot id: A0A1D7YGD0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1904616:BFF78 RS25360
gene id: 1904616:BFF78_RS25360
uniprot id: A0A1D7YEF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1904616:BFF78 RS33120
gene id: 1904616:BFF78_RS33120
uniprot id: A0A1D7YI38
names: Similarity
messages: Belongs to the peptidase M1 family.

1904616:BFF78 RS32105
gene id: 1904616:BFF78_RS32105
uniprot id: A0A1D7YHL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1904616:BFF78 RS01790
gene id: 1904616:BFF78_RS01790
uniprot id: A0A1D7YJM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1904616:BFF78 RS33715
gene id: 1904616:BFF78_RS33715
uniprot id: A0A1D7YIK0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS04225
gene id: 1904616:BFF78_RS04225
uniprot id: A0A1D7Y453
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1904616:BFF78 RS20470
gene id: 1904616:BFF78_RS20470
uniprot id: A0A1D7YC41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Mediates magnesium influx to the cytosol.

1904616:BFF78 RS10330
gene id: 1904616:BFF78_RS10330
uniprot id: A0A1D7Y7P6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS12725
gene id: 1904616:BFF78_RS12725
uniprot id: A0A1D7Y841
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS31870
gene id: 1904616:BFF78_RS31870
uniprot id: A0A1D7YHM3
names: Similarity
messages: Belongs to the DapA family.

1904616:BFF78 RS28455
gene id: 1904616:BFF78_RS28455
uniprot id: A0A1D7YFQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1904616:BFF78 RS33535
gene id: 1904616:BFF78_RS33535
uniprot id: A0A1D7YIG7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1904616:BFF78 RS36615
gene id: 1904616:BFF78_RS36615
uniprot id: A0A1D7YJS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS20815
gene id: 1904616:BFF78_RS20815
uniprot id: A0A1D7YCJ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS18445
gene id: 1904616:BFF78_RS18445
uniprot id: A0A1D7YB99
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS13465
gene id: 1904616:BFF78_RS13465
uniprot id: A0A1D7Y8U9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.
messages: In the C-terminal section; belongs to the urease beta subunit family.
messages: In the N-terminal section; belongs to the urease gamma subunit family.

1904616:BFF78 RS36595
gene id: 1904616:BFF78_RS36595
uniprot id: A0A1D7YJZ7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1904616:BFF78 RS06475
gene id: 1904616:BFF78_RS06475
uniprot id: A0A1D7Y5L1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1904616:BFF78 RS21760
gene id: 1904616:BFF78_RS21760
uniprot id: A0A1D7YCS1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1904616:BFF78 RS23525
gene id: 1904616:BFF78_RS23525
uniprot id: A0A1D7YP16
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1904616:BFF78 RS31635
gene id: 1904616:BFF78_RS31635
uniprot id: A0A1D7YHI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1904616:BFF78 RS31420
gene id: 1904616:BFF78_RS31420
uniprot id: A0A1D7YH73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1904616:BFF78 RS28625
gene id: 1904616:BFF78_RS28625
uniprot id: A0A1D7YFT4
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1904616:BFF78 RS18470
gene id: 1904616:BFF78_RS18470
uniprot id: A0A1D7YNJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS17310
gene id: 1904616:BFF78_RS17310
uniprot id: A0A1D7YAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1904616:BFF78 RS18880
gene id: 1904616:BFF78_RS18880
uniprot id: A0A1D7YB48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS23910
gene id: 1904616:BFF78_RS23910
uniprot id: A0A1D7YDL1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS10045
gene id: 1904616:BFF78_RS10045
uniprot id: A0A1D7Y6Y3
names: Similarity
messages: Belongs to the IucA/IucC family.

1904616:BFF78 RS06885
gene id: 1904616:BFF78_RS06885
uniprot id: A0A1D7Y5F5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1904616:BFF78 RS13470
gene id: 1904616:BFF78_RS13470
uniprot id: A0A1D7Y8I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1904616:BFF78 RS17060
gene id: 1904616:BFF78_RS17060
uniprot id: A0A1D7YA88
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS31460
gene id: 1904616:BFF78_RS31460
uniprot id: A0A1D7YHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS07365
gene id: 1904616:BFF78_RS07365
uniprot id: A0A1D7Y5P2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS16670
gene id: 1904616:BFF78_RS16670
uniprot id: A0A1D7YAI3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS19980
gene id: 1904616:BFF78_RS19980
uniprot id: A0A1D7YBM6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1904616:BFF78 RS29280
gene id: 1904616:BFF78_RS29280
uniprot id: A0A1D7YG49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS35485
gene id: 1904616:BFF78_RS35485
uniprot id: A0A1D7YJF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1904616:BFF78 RS19155
gene id: 1904616:BFF78_RS19155
uniprot id: A0A1D7YBR0
names: Similarity
messages: Belongs to the peptidase S13 family.

1904616:BFF78 RS35680
gene id: 1904616:BFF78_RS35680
uniprot id: A0A1D7YJD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS02965
gene id: 1904616:BFF78_RS02965
uniprot id: A0A1D7Y3Y4
names: Similarity
messages: Belongs to the Fur family.

1904616:BFF78 RS04145
gene id: 1904616:BFF78_RS04145
uniprot id: A0A1D7Y443
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS24350
gene id: 1904616:BFF78_RS24350
uniprot id: A0A1D7YDT5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34340
gene id: 1904616:BFF78_RS34340
uniprot id: A0A1D7YIP8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1904616:BFF78 RS32255
gene id: 1904616:BFF78_RS32255
uniprot id: A0A1D7YHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1904616:BFF78 RS26525
gene id: 1904616:BFF78_RS26525
uniprot id: A0A1D7YF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1904616:BFF78 RS35620
gene id: 1904616:BFF78_RS35620
uniprot id: A0A1D7YJC7
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1904616:BFF78 RS31720
gene id: 1904616:BFF78_RS31720
uniprot id: A0A1D7YHD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS05215
gene id: 1904616:BFF78_RS05215
uniprot id: A0A1D7Y4L6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1904616:BFF78 RS33475
gene id: 1904616:BFF78_RS33475
uniprot id: A0A1D7YIF8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1904616:BFF78 RS04900
gene id: 1904616:BFF78_RS04900
uniprot id: A0A1D7Y4K5
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS26565
gene id: 1904616:BFF78_RS26565
uniprot id: A0A1D7YEV0
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1904616:BFF78 RS32925
gene id: 1904616:BFF78_RS32925
uniprot id: A0A1D7YI02
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS25555
gene id: 1904616:BFF78_RS25555
uniprot id: A0A1D7YEC4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1904616:BFF78 RS41595
gene id: 1904616:BFF78_RS41595
uniprot id: A0A1D7YM71
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1904616:BFF78 RS23235
gene id: 1904616:BFF78_RS23235
uniprot id: A0A1D7YDF9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS25075
gene id: 1904616:BFF78_RS25075
uniprot id: A0A1D7YEC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS32185
gene id: 1904616:BFF78_RS32185
uniprot id: A0A1D7YHS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1904616:BFF78 RS31520
gene id: 1904616:BFF78_RS31520
uniprot id: A0A1D7YHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1904616:BFF78 RS24785
gene id: 1904616:BFF78_RS24785
uniprot id: A0A1D7YE58
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS07940
gene id: 1904616:BFF78_RS07940
uniprot id: A0A1D7Y5U5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1904616:BFF78 RS06850
gene id: 1904616:BFF78_RS06850
uniprot id: A0A1D7Y5J5
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1904616:BFF78 RS01660
gene id: 1904616:BFF78_RS01660
uniprot id: A0A1D7Y2Y4
names: Similarity
messages: Belongs to the oxoprolinase family.

1904616:BFF78 RS16625
gene id: 1904616:BFF78_RS16625
uniprot id: A0A1D7YA18
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1904616:BFF78 RS20935
gene id: 1904616:BFF78_RS20935
uniprot id: A0A1D7YCC5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1904616:BFF78 RS21900
gene id: 1904616:BFF78_RS21900
uniprot id: A0A1D7YCT9
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS41830
gene id: 1904616:BFF78_RS41830
uniprot id: A0A1D7YM94
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1904616:BFF78 RS22545
gene id: 1904616:BFF78_RS22545
uniprot id: A0A1D7YD41
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1904616:BFF78 RS28610
gene id: 1904616:BFF78_RS28610
uniprot id: A0A1D7YG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS22260
gene id: 1904616:BFF78_RS22260
uniprot id: A0A1D7YCT2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1904616:BFF78 RS21640
gene id: 1904616:BFF78_RS21640
uniprot id: A0A1D7YCN9
names: Similarity
messages: Belongs to the peptidase M24B family.

1904616:BFF78 RS36200
gene id: 1904616:BFF78_RS36200
uniprot id: A0A1D7YJT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1904616:BFF78 RS06775
gene id: 1904616:BFF78_RS06775
uniprot id: A0A1D7Y5C8
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1904616:BFF78 RS10875
gene id: 1904616:BFF78_RS10875
uniprot id: A0A1D7Y7N8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS04715
gene id: 1904616:BFF78_RS04715
uniprot id: A0A1D7Y4C4
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1904616:BFF78 RS09210
gene id: 1904616:BFF78_RS09210
uniprot id: A0A1D7Y6J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1904616:BFF78 RS24330
gene id: 1904616:BFF78_RS24330
uniprot id: A0A1D7YE56
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1904616:BFF78 RS03530
gene id: 1904616:BFF78_RS03530
uniprot id: A0A1D7Y3U0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS08870
gene id: 1904616:BFF78_RS08870
uniprot id: A0A1D7Y6C9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

1904616:BFF78 RS29990
gene id: 1904616:BFF78_RS29990
uniprot id: A0A1D7YGG4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1904616:BFF78 RS18925
gene id: 1904616:BFF78_RS18925
uniprot id: A0A1D7YB98
names: Similarity
messages: Belongs to the Nth/MutY family.

1904616:BFF78 RS33100
gene id: 1904616:BFF78_RS33100
uniprot id: A0A1D7YIA6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS17395
gene id: 1904616:BFF78_RS17395
uniprot id: A0A1D7YAJ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1904616:BFF78 RS21115
gene id: 1904616:BFF78_RS21115
uniprot id: A0A1D7YC95
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1904616:BFF78 RS35755
gene id: 1904616:BFF78_RS35755
uniprot id: A0A1D7YJJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS09840
gene id: 1904616:BFF78_RS09840
uniprot id: A0A1D7Y6Q0
names: Similarity
messages: Belongs to the thioesterase family.

1904616:BFF78 RS33790
gene id: 1904616:BFF78_RS33790
uniprot id: A0A1D7YIF7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1904616:BFF78 RS32590
gene id: 1904616:BFF78_RS32590
uniprot id: A0A1D7YI16
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1904616:BFF78 RS13510
gene id: 1904616:BFF78_RS13510
uniprot id: A0A1D7Y8N8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS28030
gene id: 1904616:BFF78_RS28030
uniprot id: A0A1D7YFJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS09525
gene id: 1904616:BFF78_RS09525
uniprot id: A0A1D7Y6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1904616:BFF78 RS38675
gene id: 1904616:BFF78_RS38675
uniprot id: A0A1D7YKS2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1904616:BFF78 RS04030
gene id: 1904616:BFF78_RS04030
uniprot id: A0A1D7YMT4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34785
gene id: 1904616:BFF78_RS34785
uniprot id: A0A1D7YJ31
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1904616:BFF78 RS05570
gene id: 1904616:BFF78_RS05570
uniprot id: A0A1D7Y4W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS30885
gene id: 1904616:BFF78_RS30885
uniprot id: A0A1D7YH55
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1904616:BFF78 RS25845
gene id: 1904616:BFF78_RS25845
uniprot id: A0A1D7YES3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1904616:BFF78 RS12715
gene id: 1904616:BFF78_RS12715
uniprot id: A0A1D7Y8H1
names: Similarity
messages: Belongs to the CdaR family.

1904616:BFF78 RS18055
gene id: 1904616:BFF78_RS18055
uniprot id: A0A1D7YB31
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1904616:BFF78 RS40980
gene id: 1904616:BFF78_RS40980
uniprot id: A0A1D7YM13
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1904616:BFF78 RS34625
gene id: 1904616:BFF78_RS34625
uniprot id: A0A1D7YIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1904616:BFF78 RS31090
gene id: 1904616:BFF78_RS31090
uniprot id: A0A1D7YHT6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1904616:BFF78 RS30285
gene id: 1904616:BFF78_RS30285
uniprot id: A0A1D7YGW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1904616:BFF78 RS09900
gene id: 1904616:BFF78_RS09900
uniprot id: A0A1D7Y6Q9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS32440
gene id: 1904616:BFF78_RS32440
uniprot id: A0A1D7YHR4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1904616:BFF78 RS12340
gene id: 1904616:BFF78_RS12340
uniprot id: A0A1D7Y8A4
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS24395
gene id: 1904616:BFF78_RS24395
uniprot id: A0A1D7YE64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1904616:BFF78 RS34410
gene id: 1904616:BFF78_RS34410
uniprot id: A0A1D7YIX4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1904616:BFF78 RS41130
gene id: 1904616:BFF78_RS41130
uniprot id: A0A1D7YM39
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS18575
gene id: 1904616:BFF78_RS18575
uniprot id: A0A1D7YNP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS17800
gene id: 1904616:BFF78_RS17800
uniprot id: A0A1D7YAK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1904616:BFF78 RS28570
gene id: 1904616:BFF78_RS28570
uniprot id: A0A1D7YFS4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1904616:BFF78 RS16480
gene id: 1904616:BFF78_RS16480
uniprot id: A0A1D7YAT7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS18750
gene id: 1904616:BFF78_RS18750
uniprot id: A0A1D7YBE9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1904616:BFF78 RS33305
gene id: 1904616:BFF78_RS33305
uniprot id: A0A1D7YI68
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1904616:BFF78 RS30230
gene id: 1904616:BFF78_RS30230
uniprot id: A0A1D7YGU0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1904616:BFF78 RS34005
gene id: 1904616:BFF78_RS34005
uniprot id: A0A1D7YJA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1904616:BFF78 RS18670
gene id: 1904616:BFF78_RS18670
uniprot id: A0A1D7YB13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS39380
gene id: 1904616:BFF78_RS39380
uniprot id: A0A1D7YL39
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1904616:BFF78 RS03370
gene id: 1904616:BFF78_RS03370
uniprot id: A0A1D7Y3R9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS36900
gene id: 1904616:BFF78_RS36900
uniprot id: A0A1D7YK49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1904616:BFF78 RS39650
gene id: 1904616:BFF78_RS39650
uniprot id: A0A1D7YLA8
names: Similarity
messages: Belongs to the peptidase M4 family.

1904616:BFF78 RS49255
gene id: 1904616:BFF78_RS49255
uniprot id: A0A1D7YM10
names: Similarity
messages: Belongs to the SurE nucleotidase family.

1904616:BFF78 RS03435
gene id: 1904616:BFF78_RS03435
uniprot id: A0A1D7Y3S5
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1904616:BFF78 RS17425
gene id: 1904616:BFF78_RS17425
uniprot id: A0A1D7YAF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1904616:BFF78 RS02320
gene id: 1904616:BFF78_RS02320
uniprot id: A0A1D7Y3V5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1904616:BFF78 RS04710
gene id: 1904616:BFF78_RS04710
uniprot id: A0A1D7Y4T3
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

1904616:BFF78 RS44735
gene id: 1904616:BFF78_RS44735
uniprot id: A0A1D7Y9A6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1904616:BFF78 RS15020
gene id: 1904616:BFF78_RS15020
uniprot id: A0A1D7Y9F5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1904616:BFF78 RS37480
gene id: 1904616:BFF78_RS37480
uniprot id: A0A1D7YPR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS05795
gene id: 1904616:BFF78_RS05795
uniprot id: A0A1D7Y4Z6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS17090
gene id: 1904616:BFF78_RS17090
uniprot id: A0A1D7YB37
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1904616:BFF78 RS11790
gene id: 1904616:BFF78_RS11790
uniprot id: A0A1D7Y7T6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1904616:BFF78 RS13515
gene id: 1904616:BFF78_RS13515
uniprot id: A0A1D7Y8P5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1904616:BFF78 RS21300
gene id: 1904616:BFF78_RS21300
uniprot id: A0A1D7YCB7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS37410
gene id: 1904616:BFF78_RS37410
uniprot id: A0A1D7YKD6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS06895
gene id: 1904616:BFF78_RS06895
uniprot id: A0A1D7Y5F3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS40035
gene id: 1904616:BFF78_RS40035
uniprot id: A0A1D7YLF9
names: Similarity
messages: Belongs to the HupF/HypC family.

1904616:BFF78 RS25860
gene id: 1904616:BFF78_RS25860
uniprot id: A0A1D7YFA0
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1904616:BFF78 RS09720
gene id: 1904616:BFF78_RS09720
uniprot id: A0A1D7Y6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS41120
gene id: 1904616:BFF78_RS41120
uniprot id: A0A1D7YM07
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1904616:BFF78 RS17190
gene id: 1904616:BFF78_RS17190
uniprot id: A0A1D7YAA6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS33980
gene id: 1904616:BFF78_RS33980
uniprot id: A0A1D7YIP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1904616:BFF78 RS23605
gene id: 1904616:BFF78_RS23605
uniprot id: A0A1D7YDG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1904616:BFF78 RS03065
gene id: 1904616:BFF78_RS03065
uniprot id: A0A1D7Y3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS31955
gene id: 1904616:BFF78_RS31955
uniprot id: A0A1D7YHH7
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1904616:BFF78 RS04325
gene id: 1904616:BFF78_RS04325
uniprot id: A0A1D7Y468
names: Similarity
messages: Belongs to the transposase 7 family.

1904616:BFF78 RS16925
gene id: 1904616:BFF78_RS16925
uniprot id: A0A1D7YAB3
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1904616:BFF78 RS19500
gene id: 1904616:BFF78_RS19500
uniprot id: A0A1D7YC77
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1904616:BFF78 RS25575
gene id: 1904616:BFF78_RS25575
uniprot id: A0A1D7YEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS32540
gene id: 1904616:BFF78_RS32540
uniprot id: A0A1D7YI05
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1904616:BFF78 RS17370
gene id: 1904616:BFF78_RS17370
uniprot id: A0A1D7YAU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1904616:BFF78 RS26800
gene id: 1904616:BFF78_RS26800
uniprot id: A0A1D7YF92
names: Similarity
messages: Belongs to the citrate synthase family.

1904616:BFF78 RS17420
gene id: 1904616:BFF78_RS17420
uniprot id: A0A1D7YAV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1904616:BFF78 RS34765
gene id: 1904616:BFF78_RS34765
uniprot id: A0A1D7YJ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1904616:BFF78 RS25240
gene id: 1904616:BFF78_RS25240
uniprot id: A0A1D7YEK4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1904616:BFF78 RS39785
gene id: 1904616:BFF78_RS39785
uniprot id: A0A1D7YLY2
names: Subcellular Location Annotation
messages: Secreted

1904616:BFF78 RS37215
gene id: 1904616:BFF78_RS37215
uniprot id: A0A1D7YPP4
names: Similarity
messages: Belongs to the CdaR family.

1904616:BFF78 RS39965
gene id: 1904616:BFF78_RS39965
uniprot id: A0A1D7YLI4
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS22065
gene id: 1904616:BFF78_RS22065
uniprot id: A0A1D7YD13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS30265
gene id: 1904616:BFF78_RS30265
uniprot id: A0A1D7YGV3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1904616:BFF78 RS26045
gene id: 1904616:BFF78_RS26045
uniprot id: A0A1D7YEL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1904616:BFF78 RS06735
gene id: 1904616:BFF78_RS06735
uniprot id: A0A1D7Y5G0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1904616:BFF78 RS06960
gene id: 1904616:BFF78_RS06960
uniprot id: A0A1D7Y5L6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS16370
gene id: 1904616:BFF78_RS16370
uniprot id: A0A1D7YAR2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Cys-Ser-Gly.
messages: Cytoplasm

1904616:BFF78 RS17140
gene id: 1904616:BFF78_RS17140
uniprot id: A0A1D7YNK0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1904616:BFF78 RS04940
gene id: 1904616:BFF78_RS04940
uniprot id: A0A1D7Y4G8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS38335
gene id: 1904616:BFF78_RS38335
uniprot id: A0A1D7YKL6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1904616:BFF78 RS29560
gene id: 1904616:BFF78_RS29560
uniprot id: A0A1D7YG97
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS17850
gene id: 1904616:BFF78_RS17850
uniprot id: A0A1D7YAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1904616:BFF78 RS25120
gene id: 1904616:BFF78_RS25120
uniprot id: A0A1D7YPH6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1904616:BFF78 RS01575
gene id: 1904616:BFF78_RS01575
uniprot id: A0A1D7Y2Z0
names: Similarity
messages: Belongs to the TPP enzyme family.

1904616:BFF78 RS40075
gene id: 1904616:BFF78_RS40075
uniprot id: A0A1D7YLL0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1904616:BFF78 RS13995
gene id: 1904616:BFF78_RS13995
uniprot id: A0A1D7Y8R6
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS28210
gene id: 1904616:BFF78_RS28210
uniprot id: A0A1D7YFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1904616:BFF78 RS15355
gene id: 1904616:BFF78_RS15355
uniprot id: A0A1D7YAA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1904616:BFF78 RS14025
gene id: 1904616:BFF78_RS14025
uniprot id: A0A1D7Y8Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1904616:BFF78 RS04200
gene id: 1904616:BFF78_RS04200
uniprot id: A0A1D7Y4J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS25055
gene id: 1904616:BFF78_RS25055
uniprot id: A0A1D7YEH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1904616:BFF78 RS30430
gene id: 1904616:BFF78_RS30430
uniprot id: A0A1D7YGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS25620
gene id: 1904616:BFF78_RS25620
uniprot id: A0A1D7YF58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1904616:BFF78 RS37940
gene id: 1904616:BFF78_RS37940
uniprot id: A0A1D7YPW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1904616:BFF78 RS06575
gene id: 1904616:BFF78_RS06575
uniprot id: A0A1D7Y573
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1904616:BFF78 RS23855
gene id: 1904616:BFF78_RS23855
uniprot id: A0A1D7YDT0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS03175
gene id: 1904616:BFF78_RS03175
uniprot id: A0A1D7Y3N7
names: Similarity
messages: Belongs to the AHA1 family.

1904616:BFF78 RS10595
gene id: 1904616:BFF78_RS10595
uniprot id: A0A1D7Y735
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1904616:BFF78 RS13745
gene id: 1904616:BFF78_RS13745
uniprot id: A0A1D7Y904
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS05955
gene id: 1904616:BFF78_RS05955
uniprot id: A0A1D7Y4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1904616:BFF78 RS18015
gene id: 1904616:BFF78_RS18015
uniprot id: A0A1D7YB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1904616:BFF78 RS39875
gene id: 1904616:BFF78_RS39875
uniprot id: A0A1D7YLC1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS20660
gene id: 1904616:BFF78_RS20660
uniprot id: A0A1D7YCB0
names: Similarity
messages: Belongs to the CdaR family.

1904616:BFF78 RS17500
gene id: 1904616:BFF78_RS17500
uniprot id: A0A1D7YAL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1904616:BFF78 RS34615
gene id: 1904616:BFF78_RS34615
uniprot id: A0A1D7YJ07
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1904616:BFF78 RS38760
gene id: 1904616:BFF78_RS38760
uniprot id: A0A1D7YLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1904616:BFF78 RS30440
gene id: 1904616:BFF78_RS30440
uniprot id: A0A1D7YGR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1904616:BFF78 RS29015
gene id: 1904616:BFF78_RS29015
uniprot id: A0A1D7YG66
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1904616:BFF78 RS03640
gene id: 1904616:BFF78_RS03640
uniprot id: A0A1D7Y4I4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1904616:BFF78 RS36520
gene id: 1904616:BFF78_RS36520
uniprot id: A0A1D7YPU8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1904616:BFF78 RS00625
gene id: 1904616:BFF78_RS00625
uniprot id: A0A1D7Y2H7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1904616:BFF78 RS10655
gene id: 1904616:BFF78_RS10655
uniprot id: A0A1D7Y7K0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1904616:BFF78 RS25265
gene id: 1904616:BFF78_RS25265
uniprot id: A0A1D7YEF8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1904616:BFF78 RS09390
gene id: 1904616:BFF78_RS09390
uniprot id: A0A1D7Y6M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1904616:BFF78 RS01800
gene id: 1904616:BFF78_RS01800
uniprot id: A0A1D7Y323
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1904616:BFF78 RS02285
gene id: 1904616:BFF78_RS02285
uniprot id: A0A1D7Y397
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1904616:BFF78 RS16795
gene id: 1904616:BFF78_RS16795
uniprot id: A0A1D7YAB7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1904616:BFF78 RS17555
gene id: 1904616:BFF78_RS17555
uniprot id: A0A1D7YAM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1904616:BFF78 RS28860
gene id: 1904616:BFF78_RS28860
uniprot id: A0A1D7YFY1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS27760
gene id: 1904616:BFF78_RS27760
uniprot id: A0A1D7YFN4
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1904616:BFF78 RS40650
gene id: 1904616:BFF78_RS40650
uniprot id: A0A1D7YLS4
names: Similarity
messages: Belongs to the GcvT family.

1904616:BFF78 RS09255
gene id: 1904616:BFF78_RS09255
uniprot id: A0A1D7Y6Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1904616:BFF78 RS28255
gene id: 1904616:BFF78_RS28255
uniprot id: A0A1D7YFY9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1904616:BFF78 RS10295
gene id: 1904616:BFF78_RS10295
uniprot id: A0A1D7Y6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1904616:BFF78 RS38075
gene id: 1904616:BFF78_RS38075
uniprot id: A0A1D7YKM6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1904616:BFF78 RS14350
gene id: 1904616:BFF78_RS14350
uniprot id: A0A1D7Y8Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1904616:BFF78 RS06225
gene id: 1904616:BFF78_RS06225
uniprot id: A0A1D7Y514
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1904616:BFF78 RS14315
gene id: 1904616:BFF78_RS14315
uniprot id: A0A1D7Y8X3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1904616:BFF78 RS28195
gene id: 1904616:BFF78_RS28195
uniprot id: A0A1D7YFM0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1904616:BFF78 RS16835
gene id: 1904616:BFF78_RS16835
uniprot id: A0A1D7YNK5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS33300
gene id: 1904616:BFF78_RS33300
uniprot id: A0A1D7YI73
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1904616:BFF78 RS40815
gene id: 1904616:BFF78_RS40815
uniprot id: A0A1D7YLY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1904616:BFF78 RS34160
gene id: 1904616:BFF78_RS34160
uniprot id: A0A1D7YIS1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1904616:BFF78 RS37570
gene id: 1904616:BFF78_RS37570
uniprot id: A0A1D7YKD7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS32225
gene id: 1904616:BFF78_RS32225
uniprot id: A0A1D7YHM6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS35805
gene id: 1904616:BFF78_RS35805
uniprot id: A0A1D7YJK0
names: Subunit
messages: Homodimer.

1904616:BFF78 RS13815
gene id: 1904616:BFF78_RS13815
uniprot id: A0A1D7Y9G6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1904616:BFF78 RS18060
gene id: 1904616:BFF78_RS18060
uniprot id: A0A1D7YAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS41160
gene id: 1904616:BFF78_RS41160
uniprot id: A0A1D7YM43
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS35040
gene id: 1904616:BFF78_RS35040
uniprot id: A0A1D7YJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS22480
gene id: 1904616:BFF78_RS22480
uniprot id: A0A1D7YD30
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1904616:BFF78 RS23425
gene id: 1904616:BFF78_RS23425
uniprot id: A0A1D7YDD5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS20000
gene id: 1904616:BFF78_RS20000
uniprot id: A0A1D7YBT9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS03590
gene id: 1904616:BFF78_RS03590
uniprot id: A0A1D7YMS5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1904616:BFF78 RS28655
gene id: 1904616:BFF78_RS28655
uniprot id: A0A1D7YFV1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1904616:BFF78 RS24685
gene id: 1904616:BFF78_RS24685
uniprot id: A0A1D7YDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1904616:BFF78 RS27180
gene id: 1904616:BFF78_RS27180
uniprot id: A0A1D7YF68
names: Similarity
messages: Belongs to the acyltransferase PapA5 family.

1904616:BFF78 RS18005
gene id: 1904616:BFF78_RS18005
uniprot id: A0A1D7YB21
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1904616:BFF78 RS24500
gene id: 1904616:BFF78_RS24500
uniprot id: A0A1D7YE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm

1904616:BFF78 RS18635
gene id: 1904616:BFF78_RS18635
uniprot id: A0A1D7YB75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1904616:BFF78 RS07190
gene id: 1904616:BFF78_RS07190
uniprot id: A0A1D7Y5H3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS29375
gene id: 1904616:BFF78_RS29375
uniprot id: A0A1D7YG76
names: Similarity
messages: Belongs to the cytochrome P450 family.

1904616:BFF78 RS19215
gene id: 1904616:BFF78_RS19215
uniprot id: A0A1D7YBE6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1904616:BFF78 RS29175
gene id: 1904616:BFF78_RS29175
uniprot id: A0A1D7YGV6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS13425
gene id: 1904616:BFF78_RS13425
uniprot id: A0A1D7Y8G6
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS14895
gene id: 1904616:BFF78_RS14895
uniprot id: A0A1D7Y9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS28645
gene id: 1904616:BFF78_RS28645
uniprot id: A0A1D7YG06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1904616:BFF78 RS32675
gene id: 1904616:BFF78_RS32675
uniprot id: A0A1D7YHX1
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS19480
gene id: 1904616:BFF78_RS19480
uniprot id: A0A1D7YBF7
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS09440
gene id: 1904616:BFF78_RS09440
uniprot id: A0A1D7Y707
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS22650
gene id: 1904616:BFF78_RS22650
uniprot id: A0A1D7YDA8
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS04895
gene id: 1904616:BFF78_RS04895
uniprot id: A0A1D7Y4G0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS02900
gene id: 1904616:BFF78_RS02900
uniprot id: A0A1D7Y3L2
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1904616:BFF78 RS31105
gene id: 1904616:BFF78_RS31105
uniprot id: A0A1D7YPU2
names: Similarity
messages: Belongs to the peptidase M1 family.

1904616:BFF78 RS04090
gene id: 1904616:BFF78_RS04090
uniprot id: A0A1D7Y458
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS41040
gene id: 1904616:BFF78_RS41040
uniprot id: A0A1D7YM23
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1904616:BFF78 RS04810
gene id: 1904616:BFF78_RS04810
uniprot id: A0A1D7Y4F3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1904616:BFF78 RS33655
gene id: 1904616:BFF78_RS33655
uniprot id: A0A1D7YIJ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS20890
gene id: 1904616:BFF78_RS20890
uniprot id: A0A1D7YC50
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1904616:BFF78 RS14310
gene id: 1904616:BFF78_RS14310
uniprot id: A0A1D7Y8X7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1904616:BFF78 RS24630
gene id: 1904616:BFF78_RS24630
uniprot id: A0A1D7YDW6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1904616:BFF78 RS10880
gene id: 1904616:BFF78_RS10880
uniprot id: A0A1D7Y7D9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1904616:BFF78 RS17175
gene id: 1904616:BFF78_RS17175
uniprot id: A0A1D7YAN4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1904616:BFF78 RS31220
gene id: 1904616:BFF78_RS31220
uniprot id: A0A1D7YHD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1904616:BFF78 RS16430
gene id: 1904616:BFF78_RS16430
uniprot id: A0A1D7YAS2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1904616:BFF78 RS19130
gene id: 1904616:BFF78_RS19130
uniprot id: A0A1D7YB97
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1904616:BFF78 RS41110
gene id: 1904616:BFF78_RS41110
uniprot id: A0A1D7YLZ1
names: Similarity
messages: Belongs to the IucA/IucC family.

1904616:BFF78 RS41895
gene id: 1904616:BFF78_RS41895
uniprot id: A0A1D7YK82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1904616:BFF78 RS13115
gene id: 1904616:BFF78_RS13115
uniprot id: A0A1D7Y8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1904616:BFF78 RS16555
gene id: 1904616:BFF78_RS16555
uniprot id: A0A1D7YA77
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS41900
gene id: 1904616:BFF78_RS41900
uniprot id: A0A1D7YMX3
names: Subcellular Location Annotation
messages: Cytoplasm

1904616:BFF78 RS31630
gene id: 1904616:BFF78_RS31630
uniprot id: A0A1D7YHC2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS32840
gene id: 1904616:BFF78_RS32840
uniprot id: A0A1D7YHZ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS35400
gene id: 1904616:BFF78_RS35400
uniprot id: A0A1D7YJY8
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS23555
gene id: 1904616:BFF78_RS23555
uniprot id: A0A1D7YDF4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1904616:BFF78 RS04280
gene id: 1904616:BFF78_RS04280
uniprot id: A0A1D7Y461
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS19825
gene id: 1904616:BFF78_RS19825
uniprot id: A0A1D7YC12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS04725
gene id: 1904616:BFF78_RS04725
uniprot id: A0A1D7Y4D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

1904616:BFF78 RS03505
gene id: 1904616:BFF78_RS03505
uniprot id: A0A1D7Y3T5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS09090
gene id: 1904616:BFF78_RS09090
uniprot id: A0A1D7YMZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1904616:BFF78 RS19870
gene id: 1904616:BFF78_RS19870
uniprot id: A0A1D7YCD4
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1904616:BFF78 RS09995
gene id: 1904616:BFF78_RS09995
uniprot id: A0A1D7Y6W2
names: Similarity
messages: Belongs to the allantoicase family.

1904616:BFF78 RS19935
gene id: 1904616:BFF78_RS19935
uniprot id: A0A1D7YCE5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1904616:BFF78 RS24695
gene id: 1904616:BFF78_RS24695
uniprot id: A0A1D7YEQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1904616:BFF78 RS12265
gene id: 1904616:BFF78_RS12265
uniprot id: A0A1D7Y7Y7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS16880
gene id: 1904616:BFF78_RS16880
uniprot id: A0A1D7YA59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1904616:BFF78 RS18765
gene id: 1904616:BFF78_RS18765
uniprot id: A0A1D7YBH9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1904616:BFF78 RS04735
gene id: 1904616:BFF78_RS04735
uniprot id: A0A1D7Y4C9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1904616:BFF78 RS16065
gene id: 1904616:BFF78_RS16065
uniprot id: A0A1D7Y9Z9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1904616:BFF78 RS08885
gene id: 1904616:BFF78_RS08885
uniprot id: A0A1D7Y6C6
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

1904616:BFF78 RS23470
gene id: 1904616:BFF78_RS23470
uniprot id: A0A1D7YDK0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1904616:BFF78 RS18945
gene id: 1904616:BFF78_RS18945
uniprot id: A0A1D7YBH5
names: Subcellular Location Annotation
messages: Cell membrane

1904616:BFF78 RS21215
gene id: 1904616:BFF78_RS21215
uniprot id: A0A1D7YCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1904616:BFF78 RS40885
gene id: 1904616:BFF78_RS40885
uniprot id: A0A1D7YM00
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS24565
gene id: 1904616:BFF78_RS24565
uniprot id: A0A1D7YDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1904616:BFF78 RS08645
gene id: 1904616:BFF78_RS08645
uniprot id: A0A1D7Y690
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS20945
gene id: 1904616:BFF78_RS20945
uniprot id: A0A1D7YCF7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1904616:BFF78 RS13435
gene id: 1904616:BFF78_RS13435
uniprot id: A0A1D7Y998
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1904616:BFF78 RS40675
gene id: 1904616:BFF78_RS40675
uniprot id: A0A1D7YLV2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1904616:BFF78 RS14955
gene id: 1904616:BFF78_RS14955
uniprot id: A0A1D7Y990
names: Similarity
messages: Belongs to the peptidase S16 family.

1904616:BFF78 RS25345
gene id: 1904616:BFF78_RS25345
uniprot id: A0A1D7YE92
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1904616:BFF78 RS22100
gene id: 1904616:BFF78_RS22100
uniprot id: A0A1D7YCV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS25975
gene id: 1904616:BFF78_RS25975
uniprot id: A0A1D7YEQ2
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS08610
gene id: 1904616:BFF78_RS08610
uniprot id: A0A1D7Y6F3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1904616:BFF78 RS35500
gene id: 1904616:BFF78_RS35500
uniprot id: A0A1D7YJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1904616:BFF78 RS41800
gene id: 1904616:BFF78_RS41800
uniprot id: A0A1D7YPZ8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1904616:BFF78 RS06115
gene id: 1904616:BFF78_RS06115
uniprot id: A0A1D7Y5F8
names: Similarity
messages: Belongs to the Dps family.

1904616:BFF78 RS39450
gene id: 1904616:BFF78_RS39450
uniprot id: A0A1D7YLA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1904616:BFF78 RS41140
gene id: 1904616:BFF78_RS41140
uniprot id: A0A1D7YLZ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1904616:BFF78 RS28470
gene id: 1904616:BFF78_RS28470
uniprot id: A0A1D7YFX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS14420
gene id: 1904616:BFF78_RS14420
uniprot id: A0A1D7Y8Y9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS34140
gene id: 1904616:BFF78_RS34140
uniprot id: A0A1D7YIU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1904616:BFF78 RS01750
gene id: 1904616:BFF78_RS01750
uniprot id: A0A1D7Y348
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1904616:BFF78 RS31620
gene id: 1904616:BFF78_RS31620
uniprot id: A0A1D7YHB8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1904616:BFF78 RS07220
gene id: 1904616:BFF78_RS07220
uniprot id: A0A1D7Y5M0
names: Similarity
messages: Belongs to the UPF0145 family.

1904616:BFF78 RS12935
gene id: 1904616:BFF78_RS12935
uniprot id: A0A1D7Y8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1904616:BFF78 RS35780
gene id: 1904616:BFF78_RS35780
uniprot id: A0A1D7YJK5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1904616:BFF78 RS30805
gene id: 1904616:BFF78_RS30805
uniprot id: A0A1D7YH42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1904616:BFF78 RS27820
gene id: 1904616:BFF78_RS27820
uniprot id: A0A1D7YFL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1904616:BFF78 RS27525
gene id: 1904616:BFF78_RS27525
uniprot id: A0A1D7YFG3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1904616:BFF78 RS14745
gene id: 1904616:BFF78_RS14745
uniprot id: A0A1D7Y9B4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1904616:BFF78 RS19115
gene id: 1904616:BFF78_RS19115
uniprot id: A0A1D7YBF9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1904616:BFF78 RS13770
gene id: 1904616:BFF78_RS13770
uniprot id: A0A1D7Y927
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1904616:BFF78 RS35330
gene id: 1904616:BFF78_RS35330
uniprot id: A0A1D7YJC8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1904616:BFF78 RS31445
gene id: 1904616:BFF78_RS31445
uniprot id: A0A1D7YH88
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS05070
gene id: 1904616:BFF78_RS05070
uniprot id: A0A1D7Y4J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1904616:BFF78 RS33505
gene id: 1904616:BFF78_RS33505
uniprot id: A0A1D7YIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS30480
gene id: 1904616:BFF78_RS30480
uniprot id: A0A1D7YGZ2
names: Similarity
messages: Belongs to the peptidase C40 family.

1904616:BFF78 RS15500
gene id: 1904616:BFF78_RS15500
uniprot id: A0A1D7Y9X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1904616:BFF78 RS18075
gene id: 1904616:BFF78_RS18075
uniprot id: A0A1D7YAQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1904616:BFF78 RS06635
gene id: 1904616:BFF78_RS06635
uniprot id: A0A1D7Y568
names: Similarity
messages: Belongs to the DDAH family.

1904616:BFF78 RS29370
gene id: 1904616:BFF78_RS29370
uniprot id: A0A1D7YGF3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1904616:BFF78 RS04880
gene id: 1904616:BFF78_RS04880
uniprot id: A0A1D7Y4F7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

1904616:BFF78 RS30755
gene id: 1904616:BFF78_RS30755
uniprot id: A0A1D7YH52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1904616:BFF78 RS18840
gene id: 1904616:BFF78_RS18840
uniprot id: A0A1D7YNU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1904616:BFF78 RS35640
gene id: 1904616:BFF78_RS35640
uniprot id: A0A1D7YJI1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1904616:BFF78 RS03810
gene id: 1904616:BFF78_RS03810
uniprot id: A0A1D7Y3Y9
names: Subcellular Location Annotation
messages: Membrane

1904616:BFF78 RS06405
gene id: 1904616:BFF78_RS06405
uniprot id: A0A1D7Y540
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1904616:BFF78 RS19025
gene id: 1904616:BFF78_RS19025
uniprot id: A0A1D7YNQ3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1904616:BFF78 RS14235
gene id: 1904616:BFF78_RS14235
uniprot id: A0A1D7Y925
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1904616:BFF78 RS06720
gene id: 1904616:BFF78_RS06720
uniprot id: A0A1D7Y5B6
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1904616:BFF78 RS36770
gene id: 1904616:BFF78_RS36770
uniprot id: A0A1D7YK15
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1904616:BFF78 RS23155
gene id: 1904616:BFF78_RS23155
uniprot id: A0A1D7YE14
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1904616:BFF78 RS20870
gene id: 1904616:BFF78_RS20870
uniprot id: A0A1D7YC96
names: Similarity
messages: Belongs to the peptidase S11 family.

1904616:BFF78 RS39330
gene id: 1904616:BFF78_RS39330
uniprot id: A0A1D7YLQ4
names: Similarity
messages: Belongs to the universal stress protein A family.

1904616:BFF78 RS01630
gene id: 1904616:BFF78_RS01630
uniprot id: A0A1D7Y304
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.