1870820:BBD41 RS22575
gene id: 1870820:BBD41_RS22575
uniprot id: A0A1B2E549
names: Subcellular Location Annotation
messages: Cytoplasm

1870820:BBD41 RS05230
gene id: 1870820:BBD41_RS05230
uniprot id: A0A1B2DWG3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1870820:BBD41 RS04700
gene id: 1870820:BBD41_RS04700
uniprot id: A0A1B2DW66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1870820:BBD41 RS17450
gene id: 1870820:BBD41_RS17450
uniprot id: A0A1B2E2I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1870820:BBD41 RS13345
gene id: 1870820:BBD41_RS13345
uniprot id: A0A1B2E0P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS17555
gene id: 1870820:BBD41_RS17555
uniprot id: A0A1B2E2U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1870820:BBD41 RS07330
gene id: 1870820:BBD41_RS07330
uniprot id: A0A1B2DXF6
names: Similarity
messages: Belongs to the UPF0758 family.

1870820:BBD41 RS17520
gene id: 1870820:BBD41_RS17520
uniprot id: A0A1B2E2J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1870820:BBD41 RS13025
gene id: 1870820:BBD41_RS13025
uniprot id: A0A1B2E0F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1870820:BBD41 RS15915
gene id: 1870820:BBD41_RS15915
uniprot id: A0A1B2E1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1870820:BBD41 RS13950
gene id: 1870820:BBD41_RS13950
uniprot id: A0A1B2E0L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1870820:BBD41 RS25060
gene id: 1870820:BBD41_RS25060
uniprot id: A0A1B2E6E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1870820:BBD41 RS17525
gene id: 1870820:BBD41_RS17525
uniprot id: A0A1B2E2P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1870820:BBD41 RS04435
gene id: 1870820:BBD41_RS04435
uniprot id: A0A1B2DVZ3
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1870820:BBD41 RS06200
gene id: 1870820:BBD41_RS06200
uniprot id: A0A1B2DWU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1870820:BBD41 RS27105
gene id: 1870820:BBD41_RS27105
uniprot id: A0A1B2E7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS03080
gene id: 1870820:BBD41_RS03080
uniprot id: A0A1B2DV87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1870820:BBD41 RS18195
gene id: 1870820:BBD41_RS18195
uniprot id: A0A1B2E2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS13890
gene id: 1870820:BBD41_RS13890
uniprot id: A0A1B2E0S5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1870820:BBD41 RS17560
gene id: 1870820:BBD41_RS17560
uniprot id: A0A1B2E2K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1870820:BBD41 RS16630
gene id: 1870820:BBD41_RS16630
uniprot id: A0A1B2E2C8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1870820:BBD41 RS24605
gene id: 1870820:BBD41_RS24605
uniprot id: A0A1B2E642
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1870820:BBD41 RS07440
gene id: 1870820:BBD41_RS07440
uniprot id: A0A1B2DXF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1870820:BBD41 RS06275
gene id: 1870820:BBD41_RS06275
uniprot id: A0A1B2DWV2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1870820:BBD41 RS17550
gene id: 1870820:BBD41_RS17550
uniprot id: A0A1B2E2K1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1870820:BBD41 RS06805
gene id: 1870820:BBD41_RS06805
uniprot id: A0A1B2DX98
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS10530
gene id: 1870820:BBD41_RS10530
uniprot id: A0A1B2DZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS12855
gene id: 1870820:BBD41_RS12855
uniprot id: A0A1B2E064
names: Similarity
messages: Belongs to the CpsD/CapB family.

1870820:BBD41 RS17000
gene id: 1870820:BBD41_RS17000
uniprot id: A0A1B2E293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS16545
gene id: 1870820:BBD41_RS16545
uniprot id: A0A1B2E268
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1870820:BBD41 RS01885
gene id: 1870820:BBD41_RS01885
uniprot id: A0A1B2DUN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS16450
gene id: 1870820:BBD41_RS16450
uniprot id: A0A1B2E224
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1870820:BBD41 RS17340
gene id: 1870820:BBD41_RS17340
uniprot id: A0A1B2E2G1
names: Similarity
messages: Belongs to the CtsR family.

1870820:BBD41 RS24090
gene id: 1870820:BBD41_RS24090
uniprot id: A0A1B2E5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS04635
gene id: 1870820:BBD41_RS04635
uniprot id: A0A1B2DW20
names: Similarity
messages: Belongs to the asp23 family.

1870820:BBD41 RS16790
gene id: 1870820:BBD41_RS16790
uniprot id: A0A1B2E2F6
names: Subcellular Location Annotation
messages: Cytoplasm

1870820:BBD41 RS05355
gene id: 1870820:BBD41_RS05355
uniprot id: A0A1B2DWF5
names: Similarity
messages: Belongs to the asp23 family.

1870820:BBD41 RS13390
gene id: 1870820:BBD41_RS13390
uniprot id: A0A1B2E0D6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1870820:BBD41 RS17590
gene id: 1870820:BBD41_RS17590
uniprot id: A0A1B2E2T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1870820:BBD41 RS04920
gene id: 1870820:BBD41_RS04920
uniprot id: A0A1B2DW79
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS07410
gene id: 1870820:BBD41_RS07410
uniprot id: A0A1B2DXE2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1870820:BBD41 RS27140
gene id: 1870820:BBD41_RS27140
uniprot id: A0A1B2E7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS14200
gene id: 1870820:BBD41_RS14200
uniprot id: A0A1B2E100
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1870820:BBD41 RS06800
gene id: 1870820:BBD41_RS06800
uniprot id: A0A1B2DX62
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1870820:BBD41 RS16515
gene id: 1870820:BBD41_RS16515
uniprot id: A0A1B2E227
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS05615
gene id: 1870820:BBD41_RS05615
uniprot id: A0A1B2E8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS04020
gene id: 1870820:BBD41_RS04020
uniprot id: A0A1B2DVS2
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS13285
gene id: 1870820:BBD41_RS13285
uniprot id: A0A1B2E0B8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1870820:BBD41 RS03950
gene id: 1870820:BBD41_RS03950
uniprot id: A0A1B2DVQ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1870820:BBD41 RS23540
gene id: 1870820:BBD41_RS23540
uniprot id: A0A1B2E5L1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1870820:BBD41 RS26555
gene id: 1870820:BBD41_RS26555
uniprot id: A0A1B2E7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1870820:BBD41 RS04185
gene id: 1870820:BBD41_RS04185
uniprot id: A0A1B2DVX7
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

1870820:BBD41 RS17635
gene id: 1870820:BBD41_RS17635
uniprot id: A0A1B2E2R3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1870820:BBD41 RS14400
gene id: 1870820:BBD41_RS14400
uniprot id: A0A1B2E108
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1870820:BBD41 RS18630
gene id: 1870820:BBD41_RS18630
uniprot id: A0A1B2E328
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1870820:BBD41 RS11455
gene id: 1870820:BBD41_RS11455
uniprot id: A0A1B2DZS5
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1870820:BBD41 RS11555
gene id: 1870820:BBD41_RS11555
uniprot id: A0A1B2DZL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1870820:BBD41 RS19805
gene id: 1870820:BBD41_RS19805
uniprot id: A0A1B2E3N6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1870820:BBD41 RS02630
gene id: 1870820:BBD41_RS02630
uniprot id: A0A1B2DV48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS07475
gene id: 1870820:BBD41_RS07475
uniprot id: A0A1B2DXH1
names: Similarity
messages: Belongs to the EamA transporter family.

1870820:BBD41 RS17600
gene id: 1870820:BBD41_RS17600
uniprot id: A0A1B2E2K4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1870820:BBD41 RS17665
gene id: 1870820:BBD41_RS17665
uniprot id: A0A1B2E2W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1870820:BBD41 RS12100
gene id: 1870820:BBD41_RS12100
uniprot id: A0A1B2E9F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS13385
gene id: 1870820:BBD41_RS13385
uniprot id: A0A1B2E0J1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1870820:BBD41 RS05955
gene id: 1870820:BBD41_RS05955
uniprot id: A0A1B2DWP8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1870820:BBD41 RS14185
gene id: 1870820:BBD41_RS14185
uniprot id: A0A1B2E0U7
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1870820:BBD41 RS12655
gene id: 1870820:BBD41_RS12655
uniprot id: A0A1B2E085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS13570
gene id: 1870820:BBD41_RS13570
uniprot id: A0A1B2E0K4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1870820:BBD41 RS20450
gene id: 1870820:BBD41_RS20450
uniprot id: A0A1B2E3Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1870820:BBD41 RS20625
gene id: 1870820:BBD41_RS20625
uniprot id: A0A1B2E445
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1870820:BBD41 RS05825
gene id: 1870820:BBD41_RS05825
uniprot id: A0A1B2DWM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1870820:BBD41 RS24840
gene id: 1870820:BBD41_RS24840
uniprot id: A0A1B2E9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1870820:BBD41 RS05415
gene id: 1870820:BBD41_RS05415
uniprot id: A0A1B2DWF4
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1870820:BBD41 RS06745
gene id: 1870820:BBD41_RS06745
uniprot id: A0A1B2DX77
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

1870820:BBD41 RS25145
gene id: 1870820:BBD41_RS25145
uniprot id: A0A1B2E6D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1870820:BBD41 RS05470
gene id: 1870820:BBD41_RS05470
uniprot id: A0A1B2DWG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1870820:BBD41 RS26165
gene id: 1870820:BBD41_RS26165
uniprot id: A0A1B2E6Y5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1870820:BBD41 RS08060
gene id: 1870820:BBD41_RS08060
uniprot id: A0A1B2DXV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS07275
gene id: 1870820:BBD41_RS07275
uniprot id: A0A1B2DXG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1870820:BBD41 RS16420
gene id: 1870820:BBD41_RS16420
uniprot id: A0A1B2E285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS24015
gene id: 1870820:BBD41_RS24015
uniprot id: A0A1B2E5U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1870820:BBD41 RS06815
gene id: 1870820:BBD41_RS06815
uniprot id: A0A1B2DX69
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1870820:BBD41 RS12605
gene id: 1870820:BBD41_RS12605
uniprot id: A0A1B2E054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS05270
gene id: 1870820:BBD41_RS05270
uniprot id: A0A1B2DWD8
names: Similarity
messages: Belongs to the RemA family.

1870820:BBD41 RS20395
gene id: 1870820:BBD41_RS20395
uniprot id: A0A1B2E3Y9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1870820:BBD41 RS14490
gene id: 1870820:BBD41_RS14490
uniprot id: A0A1B2E150
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1870820:BBD41 RS11265
gene id: 1870820:BBD41_RS11265
uniprot id: A0A1B2DZH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS10505
gene id: 1870820:BBD41_RS10505
uniprot id: A0A1B2DYY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS04370
gene id: 1870820:BBD41_RS04370
uniprot id: A0A1B2E8X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1870820:BBD41 RS17285
gene id: 1870820:BBD41_RS17285
uniprot id: A0A1B2E2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS12860
gene id: 1870820:BBD41_RS12860
uniprot id: A0A1B2E0B7
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS17490
gene id: 1870820:BBD41_RS17490
uniprot id: A0A1B2E2I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1870820:BBD41 RS20375
gene id: 1870820:BBD41_RS20375
uniprot id: A0A1B2E400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1870820:BBD41 RS25975
gene id: 1870820:BBD41_RS25975
uniprot id: A0A1B2E6W7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS04460
gene id: 1870820:BBD41_RS04460
uniprot id: A0A1B2DW33
names: Similarity
messages: Belongs to the Fur family.

1870820:BBD41 RS27150
gene id: 1870820:BBD41_RS27150
uniprot id: A0A1B2E7L8
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS20520
gene id: 1870820:BBD41_RS20520
uniprot id: A0A1B2E489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1870820:BBD41 RS15740
gene id: 1870820:BBD41_RS15740
uniprot id: A0A1B2E1W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1870820:BBD41 RS17655
gene id: 1870820:BBD41_RS17655
uniprot id: A0A1B2E2N3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1870820:BBD41 RS13195
gene id: 1870820:BBD41_RS13195
uniprot id: A0A1B2E0C3
names: Similarity
messages: Belongs to the KdgT transporter family.

1870820:BBD41 RS22905
gene id: 1870820:BBD41_RS22905
uniprot id: A0A1B2E5A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS17540
gene id: 1870820:BBD41_RS17540
uniprot id: A0A1B2E2J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1870820:BBD41 RS14560
gene id: 1870820:BBD41_RS14560
uniprot id: A0A1B2E136
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1870820:BBD41 RS12070
gene id: 1870820:BBD41_RS12070
uniprot id: A0A1B2DZY8
names: Subcellular Location Annotation
messages: Cytoplasm

1870820:BBD41 RS17570
gene id: 1870820:BBD41_RS17570
uniprot id: A0A1B2E2Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1870820:BBD41 RS24265
gene id: 1870820:BBD41_RS24265
uniprot id: A0A1B2E606
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1870820:BBD41 RS14125
gene id: 1870820:BBD41_RS14125
uniprot id: A0A1B2E0Q8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1870820:BBD41 RS17545
gene id: 1870820:BBD41_RS17545
uniprot id: A0A1B2E2L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1870820:BBD41 RS07450
gene id: 1870820:BBD41_RS07450
uniprot id: A0A1B2DXE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1870820:BBD41 RS17640
gene id: 1870820:BBD41_RS17640
uniprot id: A0A1B2E2U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1870820:BBD41 RS06925
gene id: 1870820:BBD41_RS06925
uniprot id: A0A1B2DX91
names: Similarity
messages: Belongs to the UPF0297 family.

1870820:BBD41 RS22970
gene id: 1870820:BBD41_RS22970
uniprot id: A0A1B2E5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS14190
gene id: 1870820:BBD41_RS14190
uniprot id: A0A1B2E110
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1870820:BBD41 RS25005
gene id: 1870820:BBD41_RS25005
uniprot id: A0A1B2E6A7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1870820:BBD41 RS17565
gene id: 1870820:BBD41_RS17565
uniprot id: A0A1B2E9M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1870820:BBD41 RS18815
gene id: 1870820:BBD41_RS18815
uniprot id: A0A1B2E3E5
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

1870820:BBD41 RS26645
gene id: 1870820:BBD41_RS26645
uniprot id: A0A1B2E752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS10355
gene id: 1870820:BBD41_RS10355
uniprot id: A0A1B2DZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1870820:BBD41 RS17485
gene id: 1870820:BBD41_RS17485
uniprot id: A0A1B2E2L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1870820:BBD41 RS17435
gene id: 1870820:BBD41_RS17435
uniprot id: A0A1B2E2K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1870820:BBD41 RS12825
gene id: 1870820:BBD41_RS12825
uniprot id: A0A1B2E096
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

1870820:BBD41 RS17440
gene id: 1870820:BBD41_RS17440
uniprot id: A0A1B2E2H7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1870820:BBD41 RS05495
gene id: 1870820:BBD41_RS05495
uniprot id: A0A1B2DWK1
names: Similarity
messages: Belongs to the UPF0473 family.

1870820:BBD41 RS08730
gene id: 1870820:BBD41_RS08730
uniprot id: A0A1B2DY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS03985
gene id: 1870820:BBD41_RS03985
uniprot id: A0A1B2DVQ1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1870820:BBD41 RS17360
gene id: 1870820:BBD41_RS17360
uniprot id: A0A1B2E2F9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1870820:BBD41 RS19675
gene id: 1870820:BBD41_RS19675
uniprot id: A0A1B2E3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1870820:BBD41 RS26135
gene id: 1870820:BBD41_RS26135
uniprot id: A0A1B2E6Y8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1870820:BBD41 RS26035
gene id: 1870820:BBD41_RS26035
uniprot id: A0A1B2E739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

1870820:BBD41 RS14010
gene id: 1870820:BBD41_RS14010
uniprot id: A0A1B2E0U4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1870820:BBD41 RS17645
gene id: 1870820:BBD41_RS17645
uniprot id: A0A1B2E2P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1870820:BBD41 RS05960
gene id: 1870820:BBD41_RS05960
uniprot id: A0A1B2DWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS24615
gene id: 1870820:BBD41_RS24615
uniprot id: A0A1B2E9T4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1870820:BBD41 RS20410
gene id: 1870820:BBD41_RS20410
uniprot id: A0A1B2E3Y1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1870820:BBD41 RS05365
gene id: 1870820:BBD41_RS05365
uniprot id: A0A1B2DWH8
names: Similarity
messages: Belongs to the UPF0358 family.

1870820:BBD41 RS16800
gene id: 1870820:BBD41_RS16800
uniprot id: A0A1B2E2C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1870820:BBD41 RS07445
gene id: 1870820:BBD41_RS07445
uniprot id: A0A1B2DXH6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1870820:BBD41 RS02230
gene id: 1870820:BBD41_RS02230
uniprot id: A0A1B2DUU4
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS05260
gene id: 1870820:BBD41_RS05260
uniprot id: A0A1B2DWE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1870820:BBD41 RS18100
gene id: 1870820:BBD41_RS18100
uniprot id: A0A1B2E330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS09880
gene id: 1870820:BBD41_RS09880
uniprot id: A0A1B2DYT0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1870820:BBD41 RS20385
gene id: 1870820:BBD41_RS20385
uniprot id: A0A1B2E405
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1870820:BBD41 RS19990
gene id: 1870820:BBD41_RS19990
uniprot id: A0A1B2E3Q7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1870820:BBD41 RS05845
gene id: 1870820:BBD41_RS05845
uniprot id: A0A1B2DWX1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1870820:BBD41 RS24640
gene id: 1870820:BBD41_RS24640
uniprot id: A0A1B2E6D3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1870820:BBD41 RS07125
gene id: 1870820:BBD41_RS07125
uniprot id: A0A1B2DXA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1870820:BBD41 RS21560
gene id: 1870820:BBD41_RS21560
uniprot id: A0A1B2E4T4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1870820:BBD41 RS01950
gene id: 1870820:BBD41_RS01950
uniprot id: A0A1B2DUP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1870820:BBD41 RS12550
gene id: 1870820:BBD41_RS12550
uniprot id: A0A1B2E003
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1870820:BBD41 RS13175
gene id: 1870820:BBD41_RS13175
uniprot id: A0A1B2E0L7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1870820:BBD41 RS05200
gene id: 1870820:BBD41_RS05200
uniprot id: A0A1B2DWE9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1870820:BBD41 RS16500
gene id: 1870820:BBD41_RS16500
uniprot id: A0A1B2E283
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1870820:BBD41 RS17460
gene id: 1870820:BBD41_RS17460
uniprot id: A0A1B2E2I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1870820:BBD41 RS10680
gene id: 1870820:BBD41_RS10680
uniprot id: A0A1B2DZ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

1870820:BBD41 RS20715
gene id: 1870820:BBD41_RS20715
uniprot id: A0A1B2E430
names: Similarity
messages: Belongs to the glutamine synthetase family.

1870820:BBD41 RS14565
gene id: 1870820:BBD41_RS14565
uniprot id: A0A1B2E0Z5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1870820:BBD41 RS17400
gene id: 1870820:BBD41_RS17400
uniprot id: A0A1B2E9G9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1870820:BBD41 RS06915
gene id: 1870820:BBD41_RS06915
uniprot id: A0A1B2DXB7
names: Similarity
messages: Belongs to the UPF0473 family.

1870820:BBD41 RS16870
gene id: 1870820:BBD41_RS16870
uniprot id: A0A1B2E2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1870820:BBD41 RS22340
gene id: 1870820:BBD41_RS22340
uniprot id: A0A1B2E4Z4
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

1870820:BBD41 RS14175
gene id: 1870820:BBD41_RS14175
uniprot id: A0A1B2E0S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1870820:BBD41 RS13990
gene id: 1870820:BBD41_RS13990
uniprot id: A0A1B2E0W6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1870820:BBD41 RS17505
gene id: 1870820:BBD41_RS17505
uniprot id: A0A1B2E2T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1870820:BBD41 RS21675
gene id: 1870820:BBD41_RS21675
uniprot id: A0A1B2E4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS18655
gene id: 1870820:BBD41_RS18655
uniprot id: A0A1B2E366
names: Similarity
messages: Belongs to the Fur family.

1870820:BBD41 RS14360
gene id: 1870820:BBD41_RS14360
uniprot id: A0A1B2E133
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1870820:BBD41 RS19105
gene id: 1870820:BBD41_RS19105
uniprot id: A0A1B2E3D9
names: Similarity
messages: Belongs to the thioredoxin family.

1870820:BBD41 RS17595
gene id: 1870820:BBD41_RS17595
uniprot id: A0A1B2E2N1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1870820:BBD41 RS19175
gene id: 1870820:BBD41_RS19175
uniprot id: A0A1B2E3L4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1870820:BBD41 RS25100
gene id: 1870820:BBD41_RS25100
uniprot id: A0A1B2E6K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1870820:BBD41 RS19665
gene id: 1870820:BBD41_RS19665
uniprot id: A0A1B2E3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1870820:BBD41 RS24530
gene id: 1870820:BBD41_RS24530
uniprot id: A0A1B2E9Q4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1870820:BBD41 RS10675
gene id: 1870820:BBD41_RS10675
uniprot id: A0A1B2DZ47
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1870820:BBD41 RS20390
gene id: 1870820:BBD41_RS20390
uniprot id: A0A1B2E3Z5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1870820:BBD41 RS09005
gene id: 1870820:BBD41_RS09005
uniprot id: A0A1B2DY79
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS06400
gene id: 1870820:BBD41_RS06400
uniprot id: A0A1B2DX14
names: Similarity
messages: Belongs to the CvfB family.

1870820:BBD41 RS14480
gene id: 1870820:BBD41_RS14480
uniprot id: A0A1B2E154
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1870820:BBD41 RS22690
gene id: 1870820:BBD41_RS22690
uniprot id: A0A1B2E573
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1870820:BBD41 RS03915
gene id: 1870820:BBD41_RS03915
uniprot id: A0A1B2DVT2
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

1870820:BBD41 RS17380
gene id: 1870820:BBD41_RS17380
uniprot id: A0A1B2E2G7
names: Similarity
messages: Belongs to the ycf81 family.

1870820:BBD41 RS25905
gene id: 1870820:BBD41_RS25905
uniprot id: A0A1B2E702
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1870820:BBD41 RS13955
gene id: 1870820:BBD41_RS13955
uniprot id: A0A1B2E0S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1870820:BBD41 RS24620
gene id: 1870820:BBD41_RS24620
uniprot id: A0A1B2E634
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1870820:BBD41 RS25055
gene id: 1870820:BBD41_RS25055
uniprot id: A0A1B2E6C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1870820:BBD41 RS17630
gene id: 1870820:BBD41_RS17630
uniprot id: A0A1B2E2L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1870820:BBD41 RS07050
gene id: 1870820:BBD41_RS07050
uniprot id: A0A1B2DX88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1870820:BBD41 RS04400
gene id: 1870820:BBD41_RS04400
uniprot id: A0A1B2DVY6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1870820:BBD41 RS07285
gene id: 1870820:BBD41_RS07285
uniprot id: A0A1B2DXB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1870820:BBD41 RS18055
gene id: 1870820:BBD41_RS18055
uniprot id: A0A1B2E2T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1870820:BBD41 RS18780
gene id: 1870820:BBD41_RS18780
uniprot id: A0A1B2E352
names: Similarity
messages: Belongs to the PspA/IM30 family.

1870820:BBD41 RS17685
gene id: 1870820:BBD41_RS17685
uniprot id: A0A1B2E2S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1870820:BBD41 RS04110
gene id: 1870820:BBD41_RS04110
uniprot id: A0A1B2DVT0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

1870820:BBD41 RS13685
gene id: 1870820:BBD41_RS13685
uniprot id: A0A1B2E0U6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1870820:BBD41 RS13665
gene id: 1870820:BBD41_RS13665
uniprot id: A0A1B2E0H6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1870820:BBD41 RS17605
gene id: 1870820:BBD41_RS17605
uniprot id: A0A1B2E2M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1870820:BBD41 RS19070
gene id: 1870820:BBD41_RS19070
uniprot id: A0A1B2E3J1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1870820:BBD41 RS17620
gene id: 1870820:BBD41_RS17620
uniprot id: A0A1B2E2L7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1870820:BBD41 RS17650
gene id: 1870820:BBD41_RS17650
uniprot id: A0A1B2E2L2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1870820:BBD41 RS16610
gene id: 1870820:BBD41_RS16610
uniprot id: A0A1B2E255
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1870820:BBD41 RS11395
gene id: 1870820:BBD41_RS11395
uniprot id: A0A1B2DZF4
names: Similarity
messages: Belongs to the RutC family.

1870820:BBD41 RS13885
gene id: 1870820:BBD41_RS13885
uniprot id: A0A1B2E9C0
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1870820:BBD41 RS04180
gene id: 1870820:BBD41_RS04180
uniprot id: A0A1B2DVU3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1870820:BBD41 RS10460
gene id: 1870820:BBD41_RS10460
uniprot id: A0A1B2DZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS23315
gene id: 1870820:BBD41_RS23315
uniprot id: A0A1B2E5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS04580
gene id: 1870820:BBD41_RS04580
uniprot id: A0A1B2DW21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1870820:BBD41 RS24545
gene id: 1870820:BBD41_RS24545
uniprot id: A0A1B2E630
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1870820:BBD41 RS26155
gene id: 1870820:BBD41_RS26155
uniprot id: A0A1B2E761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS20050
gene id: 1870820:BBD41_RS20050
uniprot id: A0A1B2E3T1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1870820:BBD41 RS19040
gene id: 1870820:BBD41_RS19040
uniprot id: A0A1B2E3I1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1870820:BBD41 RS04740
gene id: 1870820:BBD41_RS04740
uniprot id: A0A1B2DW44
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

1870820:BBD41 RS06520
gene id: 1870820:BBD41_RS06520
uniprot id: A0A1B2DX19
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1870820:BBD41 RS24515
gene id: 1870820:BBD41_RS24515
uniprot id: A0A1B2E644
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1870820:BBD41 RS27440
gene id: 1870820:BBD41_RS27440
uniprot id: A0A1B2EA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1870820:BBD41 RS17830
gene id: 1870820:BBD41_RS17830
uniprot id: A0A1B2E2R8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1870820:BBD41 RS17580
gene id: 1870820:BBD41_RS17580
uniprot id: A0A1B2E2K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1870820:BBD41 RS21475
gene id: 1870820:BBD41_RS21475
uniprot id: A0A1B2E4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS05950
gene id: 1870820:BBD41_RS05950
uniprot id: A0A1B2DWZ0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1870820:BBD41 RS17005
gene id: 1870820:BBD41_RS17005
uniprot id: A0A1B2E2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS18095
gene id: 1870820:BBD41_RS18095
uniprot id: A0A1B2E2Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS13490
gene id: 1870820:BBD41_RS13490
uniprot id: A0A1B2E0K9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1870820:BBD41 RS08520
gene id: 1870820:BBD41_RS08520
uniprot id: A0A1B2DY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS18065
gene id: 1870820:BBD41_RS18065
uniprot id: A0A1B2E2T1
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS17445
gene id: 1870820:BBD41_RS17445
uniprot id: A0A1B2E2J4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1870820:BBD41 RS29365
gene id: 1870820:BBD41_RS29365
uniprot id: A0A1B2E8J2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1870820:BBD41 RS21010
gene id: 1870820:BBD41_RS21010
uniprot id: A0A1B2E4A7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1870820:BBD41 RS08405
gene id: 1870820:BBD41_RS08405
uniprot id: A0A1B2DXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS24520
gene id: 1870820:BBD41_RS24520
uniprot id: A0A1B2E9W2
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

1870820:BBD41 RS14895
gene id: 1870820:BBD41_RS14895
uniprot id: A0A1B2E196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS17820
gene id: 1870820:BBD41_RS17820
uniprot id: A0A1B2E2T6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1870820:BBD41 RS25225
gene id: 1870820:BBD41_RS25225
uniprot id: A0A1B2E6F3
names: Similarity
messages: Belongs to the UPF0234 family.

1870820:BBD41 RS26570
gene id: 1870820:BBD41_RS26570
uniprot id: A0A1B2E748
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS16525
gene id: 1870820:BBD41_RS16525
uniprot id: A0A1B2E2A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1870820:BBD41 RS21910
gene id: 1870820:BBD41_RS21910
uniprot id: A0A1B2E4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS16445
gene id: 1870820:BBD41_RS16445
uniprot id: A0A1B2E274
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1870820:BBD41 RS15865
gene id: 1870820:BBD41_RS15865
uniprot id: A0A1B2E1P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1870820:BBD41 RS19680
gene id: 1870820:BBD41_RS19680
uniprot id: A0A1B2E3M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1870820:BBD41 RS05440
gene id: 1870820:BBD41_RS05440
uniprot id: A0A1B2DWF7
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS13015
gene id: 1870820:BBD41_RS13015
uniprot id: A0A1B2E0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1870820:BBD41 RS16540
gene id: 1870820:BBD41_RS16540
uniprot id: A0A1B2E209
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1870820:BBD41 RS06330
gene id: 1870820:BBD41_RS06330
uniprot id: A0A1B2DWY7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1870820:BBD41 RS21335
gene id: 1870820:BBD41_RS21335
uniprot id: A0A1B2E4G2
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1870820:BBD41 RS08075
gene id: 1870820:BBD41_RS08075
uniprot id: A0A1B2DXW3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1870820:BBD41 RS03085
gene id: 1870820:BBD41_RS03085
uniprot id: A0A1B2DVD4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1870820:BBD41 RS16635
gene id: 1870820:BBD41_RS16635
uniprot id: A0A1B2E232
names: Subcellular Location Annotation
messages: Membrane

1870820:BBD41 RS17530
gene id: 1870820:BBD41_RS17530
uniprot id: A0A1B2E2S7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1870820:BBD41 RS17670
gene id: 1870820:BBD41_RS17670
uniprot id: A0A1B2E2M6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1870820:BBD41 RS27100
gene id: 1870820:BBD41_RS27100
uniprot id: A0A1B2E7L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane