1821621:A8C75 RS01925
gene id: 1821621:A8C75_RS01925
uniprot id: A0A1A9EU84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1821621:A8C75 RS04975
gene id: 1821621:A8C75_RS04975
uniprot id: A0A1A9EVX9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1821621:A8C75 RS04155
gene id: 1821621:A8C75_RS04155
uniprot id: A0A1A9EV82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1821621:A8C75 RS13205
gene id: 1821621:A8C75_RS13205
uniprot id: A0A1A9F0R2
names: Similarity
messages: Belongs to the ArsC family.

1821621:A8C75 RS18750
gene id: 1821621:A8C75_RS18750
uniprot id: A0A1A9F373
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS09180
gene id: 1821621:A8C75_RS09180
uniprot id: A0A1A9EXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1821621:A8C75 RS21510
gene id: 1821621:A8C75_RS21510
uniprot id: A0A1A9F4M2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS19510
gene id: 1821621:A8C75_RS19510
uniprot id: A0A1A9F2X1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS02045
gene id: 1821621:A8C75_RS02045
uniprot id: A0A1A9ET78
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1821621:A8C75 RS02790
gene id: 1821621:A8C75_RS02790
uniprot id: A0A1A9EUP2
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS13755
gene id: 1821621:A8C75_RS13755
uniprot id: A0A1A9F0M7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS18190
gene id: 1821621:A8C75_RS18190
uniprot id: A0A1A9F2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS20285
gene id: 1821621:A8C75_RS20285
uniprot id: A0A1A9F493
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1821621:A8C75 RS00010
gene id: 1821621:A8C75_RS00010
uniprot id: A0A1A9ET06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1821621:A8C75 RS17985
gene id: 1821621:A8C75_RS17985
uniprot id: A0A1A9F1Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1821621:A8C75 RS16930
gene id: 1821621:A8C75_RS16930
uniprot id: A0A1A9F1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1821621:A8C75 RS20265
gene id: 1821621:A8C75_RS20265
uniprot id: A0A1A9F332
names: Similarity
messages: Belongs to the UPF0758 family.

1821621:A8C75 RS01515
gene id: 1821621:A8C75_RS01515
uniprot id: A0A1A9EUD5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1821621:A8C75 RS14795
gene id: 1821621:A8C75_RS14795
uniprot id: A0A1A9F092
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS05960
gene id: 1821621:A8C75_RS05960
uniprot id: A0A1A9EW93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS20485
gene id: 1821621:A8C75_RS20485
uniprot id: A0A1A9F365
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1821621:A8C75 RS17015
gene id: 1821621:A8C75_RS17015
uniprot id: A0A1A9F1M4
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS18610
gene id: 1821621:A8C75_RS18610
uniprot id: A0A1A9F3G8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1821621:A8C75 RS13945
gene id: 1821621:A8C75_RS13945
uniprot id: A0A1A9F046
names: Similarity
messages: Belongs to the LOG family.

1821621:A8C75 RS21375
gene id: 1821621:A8C75_RS21375
uniprot id: A0A1A9F3M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1821621:A8C75 RS02560
gene id: 1821621:A8C75_RS02560
uniprot id: A0A1A9EUP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1821621:A8C75 RS03720
gene id: 1821621:A8C75_RS03720
uniprot id: A0A1A9EUU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS16705
gene id: 1821621:A8C75_RS16705
uniprot id: A0A1A9F1A2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1821621:A8C75 RS00705
gene id: 1821621:A8C75_RS00705
uniprot id: A0A1A9EU70
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1821621:A8C75 RS22005
gene id: 1821621:A8C75_RS22005
uniprot id: A0A1A9F556
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1821621:A8C75 RS09560
gene id: 1821621:A8C75_RS09560
uniprot id: A0A1A9EX34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS02325
gene id: 1821621:A8C75_RS02325
uniprot id: A0A1A9EUT5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1821621:A8C75 RS21120
gene id: 1821621:A8C75_RS21120
uniprot id: A0A1A9F4B2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1821621:A8C75 RS20365
gene id: 1821621:A8C75_RS20365
uniprot id: A0A1A9F4F7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1821621:A8C75 RS05685
gene id: 1821621:A8C75_RS05685
uniprot id: A0A1A9EWA9
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1821621:A8C75 RS14850
gene id: 1821621:A8C75_RS14850
uniprot id: A0A1A9F0G3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS15230
gene id: 1821621:A8C75_RS15230
uniprot id: A0A1A9F0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1821621:A8C75 RS05205
gene id: 1821621:A8C75_RS05205
uniprot id: A0A1A9EVW0
names: Similarity
messages: Belongs to the UPF0102 family.

1821621:A8C75 RS19530
gene id: 1821621:A8C75_RS19530
uniprot id: A0A1A9F2K5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS18865
gene id: 1821621:A8C75_RS18865
uniprot id: A0A1A9F395
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS09325
gene id: 1821621:A8C75_RS09325
uniprot id: A0A1A9EXW9
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1821621:A8C75 RS19675
gene id: 1821621:A8C75_RS19675
uniprot id: A0A1A9F3P1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS19555
gene id: 1821621:A8C75_RS19555
uniprot id: A0A1A9F3M1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS20200
gene id: 1821621:A8C75_RS20200
uniprot id: A0A1A9F3A3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1821621:A8C75 RS00325
gene id: 1821621:A8C75_RS00325
uniprot id: A0A1A9EU02
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS06175
gene id: 1821621:A8C75_RS06175
uniprot id: A0A1A9EWS3
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1821621:A8C75 RS17250
gene id: 1821621:A8C75_RS17250
uniprot id: A0A1A9F121
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1821621:A8C75 RS22765
gene id: 1821621:A8C75_RS22765
uniprot id: A0A1A9F589
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1821621:A8C75 RS20110
gene id: 1821621:A8C75_RS20110
uniprot id: A0A1A9F2V6
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1821621:A8C75 RS16390
gene id: 1821621:A8C75_RS16390
uniprot id: A0A1A9F1Z1
names: Similarity
messages: Belongs to the IlvD/Edd family.

1821621:A8C75 RS01340
gene id: 1821621:A8C75_RS01340
uniprot id: A0A1A9ETM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1821621:A8C75 RS05025
gene id: 1821621:A8C75_RS05025
uniprot id: A0A1A9EWJ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1821621:A8C75 RS14025
gene id: 1821621:A8C75_RS14025
uniprot id: A0A1A9F003
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS05165
gene id: 1821621:A8C75_RS05165
uniprot id: A0A1A9EVM4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1821621:A8C75 RS06455
gene id: 1821621:A8C75_RS06455
uniprot id: A0A1A9EXA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1821621:A8C75 RS14610
gene id: 1821621:A8C75_RS14610
uniprot id: A0A1A9EZT7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1821621:A8C75 RS17440
gene id: 1821621:A8C75_RS17440
uniprot id: A0A1A9F160
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS17750
gene id: 1821621:A8C75_RS17750
uniprot id: A0A1A9F2P4
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1821621:A8C75 RS02020
gene id: 1821621:A8C75_RS02020
uniprot id: A0A1A9EUX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS13220
gene id: 1821621:A8C75_RS13220
uniprot id: A0A1A9F5A8
names: Similarity
messages: Belongs to the SufE family.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1821621:A8C75 RS00830
gene id: 1821621:A8C75_RS00830
uniprot id: A0A1A9F494
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS07585
gene id: 1821621:A8C75_RS07585
uniprot id: A0A1A9EXX1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS10855
gene id: 1821621:A8C75_RS10855
uniprot id: A0A1A9EXR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS05495
gene id: 1821621:A8C75_RS05495
uniprot id: A0A1A9EWT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1821621:A8C75 RS14930
gene id: 1821621:A8C75_RS14930
uniprot id: A0A1A9F0W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1821621:A8C75 RS04060
gene id: 1821621:A8C75_RS04060
uniprot id: A0A1A9EW02
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1821621:A8C75 RS21125
gene id: 1821621:A8C75_RS21125
uniprot id: A0A1A9F4P7
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1821621:A8C75 RS21495
gene id: 1821621:A8C75_RS21495
uniprot id: A0A1A9F4I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1821621:A8C75 RS20740
gene id: 1821621:A8C75_RS20740
uniprot id: A0A1A9F4M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS04920
gene id: 1821621:A8C75_RS04920
uniprot id: A0A1A9F4F3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1821621:A8C75 RS06450
gene id: 1821621:A8C75_RS06450
uniprot id: A0A1A9EWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS11770
gene id: 1821621:A8C75_RS11770
uniprot id: A0A1A9EZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1821621:A8C75 RS02295
gene id: 1821621:A8C75_RS02295
uniprot id: A0A1A9EUF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1821621:A8C75 RS20645
gene id: 1821621:A8C75_RS20645
uniprot id: A0A1A9F394
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1821621:A8C75 RS11575
gene id: 1821621:A8C75_RS11575
uniprot id: A0A1A9EZI8
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1821621:A8C75 RS22515
gene id: 1821621:A8C75_RS22515
uniprot id: A0A1A9F518
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS07480
gene id: 1821621:A8C75_RS07480
uniprot id: A0A1A9EWU1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1821621:A8C75 RS19740
gene id: 1821621:A8C75_RS19740
uniprot id: A0A1A9F3Q2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS12470
gene id: 1821621:A8C75_RS12470
uniprot id: A0A1A9EZ34
names: Similarity
messages: Belongs to the TPP enzyme family.

1821621:A8C75 RS04210
gene id: 1821621:A8C75_RS04210
uniprot id: A0A1A9EV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1821621:A8C75 RS04580
gene id: 1821621:A8C75_RS04580
uniprot id: A0A1A9EVA8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS05770
gene id: 1821621:A8C75_RS05770
uniprot id: A0A1A9EW29
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1821621:A8C75 RS22595
gene id: 1821621:A8C75_RS22595
uniprot id: A0A1A9F4T4
names: Similarity
messages: Belongs to the IucA/IucC family.

1821621:A8C75 RS04260
gene id: 1821621:A8C75_RS04260
uniprot id: A0A1A9EVA7
names: Similarity
messages: Belongs to the type III secretion exporter family.

1821621:A8C75 RS20255
gene id: 1821621:A8C75_RS20255
uniprot id: A0A1A9F4D5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1821621:A8C75 RS22355
gene id: 1821621:A8C75_RS22355
uniprot id: A0A1A9F3Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1821621:A8C75 RS19340
gene id: 1821621:A8C75_RS19340
uniprot id: A0A1A9F2T7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS09705
gene id: 1821621:A8C75_RS09705
uniprot id: A0A1A9EYX0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1821621:A8C75 RS22160
gene id: 1821621:A8C75_RS22160
uniprot id: A0A1A9F5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1821621:A8C75 RS10495
gene id: 1821621:A8C75_RS10495
uniprot id: A0A1A9EYZ7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS04495
gene id: 1821621:A8C75_RS04495
uniprot id: A0A1A9EVW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

1821621:A8C75 RS15580
gene id: 1821621:A8C75_RS15580
uniprot id: A0A1A9F0Y7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS11105
gene id: 1821621:A8C75_RS11105
uniprot id: A0A1A9EYG6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1821621:A8C75 RS05565
gene id: 1821621:A8C75_RS05565
uniprot id: A0A1A9EVZ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS10925
gene id: 1821621:A8C75_RS10925
uniprot id: A0A1A9EYH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS07935
gene id: 1821621:A8C75_RS07935
uniprot id: A0A1A9EWA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1821621:A8C75 RS01490
gene id: 1821621:A8C75_RS01490
uniprot id: A0A1A9EUP9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS19365
gene id: 1821621:A8C75_RS19365
uniprot id: A0A1A9F2J5
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS07990
gene id: 1821621:A8C75_RS07990
uniprot id: A0A1A9EY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1821621:A8C75 RS22750
gene id: 1821621:A8C75_RS22750
uniprot id: A0A1A9F552
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1821621:A8C75 RS14445
gene id: 1821621:A8C75_RS14445
uniprot id: A0A1A9F0E2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1821621:A8C75 RS18195
gene id: 1821621:A8C75_RS18195
uniprot id: A0A1A9F286
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1821621:A8C75 RS18985
gene id: 1821621:A8C75_RS18985
uniprot id: A0A1A9F2M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS20635
gene id: 1821621:A8C75_RS20635
uniprot id: A0A1A9F4K6
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS19115
gene id: 1821621:A8C75_RS19115
uniprot id: A0A1A9F5K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1821621:A8C75 RS16015
gene id: 1821621:A8C75_RS16015
uniprot id: A0A1A9F1F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1821621:A8C75 RS19265
gene id: 1821621:A8C75_RS19265
uniprot id: A0A1A9F2H6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1821621:A8C75 RS05100
gene id: 1821621:A8C75_RS05100
uniprot id: A0A1A9EUT3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1821621:A8C75 RS23480
gene id: 1821621:A8C75_RS23480
uniprot id: A0A1A9F572
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1821621:A8C75 RS06560
gene id: 1821621:A8C75_RS06560
uniprot id: A0A1A9EWZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS00680
gene id: 1821621:A8C75_RS00680
uniprot id: A0A1A9ESG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1821621:A8C75 RS05225
gene id: 1821621:A8C75_RS05225
uniprot id: A0A1A9EVN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1821621:A8C75 RS21780
gene id: 1821621:A8C75_RS21780
uniprot id: A0A1A9F3P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1821621:A8C75 RS14270
gene id: 1821621:A8C75_RS14270
uniprot id: A0A1A9F183
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1821621:A8C75 RS04150
gene id: 1821621:A8C75_RS04150
uniprot id: A0A1A9EV11
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1821621:A8C75 RS19060
gene id: 1821621:A8C75_RS19060
uniprot id: A0A1A9F2E8
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS09255
gene id: 1821621:A8C75_RS09255
uniprot id: A0A1A9EY31
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1821621:A8C75 RS06620
gene id: 1821621:A8C75_RS06620
uniprot id: A0A1A9EXE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS19910
gene id: 1821621:A8C75_RS19910
uniprot id: A0A1A9F3Q1
names: Similarity
messages: Belongs to the PspA/IM30 family.

1821621:A8C75 RS14010
gene id: 1821621:A8C75_RS14010
uniprot id: A0A1A9EZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS02915
gene id: 1821621:A8C75_RS02915
uniprot id: A0A1A9EUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1821621:A8C75 RS18520
gene id: 1821621:A8C75_RS18520
uniprot id: A0A1A9F254
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1821621:A8C75 RS12770
gene id: 1821621:A8C75_RS12770
uniprot id: A0A1A9EZC3
names: Similarity
messages: Belongs to the MEMO1 family.

1821621:A8C75 RS00730
gene id: 1821621:A8C75_RS00730
uniprot id: A0A1A9ESH2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1821621:A8C75 RS20470
gene id: 1821621:A8C75_RS20470
uniprot id: A0A1A9F3F8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1821621:A8C75 RS18710
gene id: 1821621:A8C75_RS18710
uniprot id: A0A1A9F3I8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS04390
gene id: 1821621:A8C75_RS04390
uniprot id: A0A1A9EVY0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1821621:A8C75 RS08305
gene id: 1821621:A8C75_RS08305
uniprot id: A0A1A9F5L1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1821621:A8C75 RS03640
gene id: 1821621:A8C75_RS03640
uniprot id: A0A1A9EV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS09440
gene id: 1821621:A8C75_RS09440
uniprot id: A0A1A9EX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1821621:A8C75 RS21420
gene id: 1821621:A8C75_RS21420
uniprot id: A0A1A9F396
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1821621:A8C75 RS01900
gene id: 1821621:A8C75_RS01900
uniprot id: A0A1A9EU03
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1821621:A8C75 RS02635
gene id: 1821621:A8C75_RS02635
uniprot id: A0A1A9EVB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1821621:A8C75 RS13250
gene id: 1821621:A8C75_RS13250
uniprot id: A0A1A9F016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS20705
gene id: 1821621:A8C75_RS20705
uniprot id: A0A1A9F356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1821621:A8C75 RS19875
gene id: 1821621:A8C75_RS19875
uniprot id: A0A1A9F3S4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS14170
gene id: 1821621:A8C75_RS14170
uniprot id: A0A1A9F0T4
names: Cofactor
messages: Binds 2 iron ions per subunit.

1821621:A8C75 RS11400
gene id: 1821621:A8C75_RS11400
uniprot id: A0A1A9EZR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1821621:A8C75 RS18280
gene id: 1821621:A8C75_RS18280
uniprot id: A0A1A9F225
names: Similarity
messages: Belongs to the peptidase S13 family.

1821621:A8C75 RS11875
gene id: 1821621:A8C75_RS11875
uniprot id: A0A1A9F002
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS21065
gene id: 1821621:A8C75_RS21065
uniprot id: A0A1A9F3D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS19630
gene id: 1821621:A8C75_RS19630
uniprot id: A0A1A9F2Y7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1821621:A8C75 RS15260
gene id: 1821621:A8C75_RS15260
uniprot id: A0A1A9F1D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1821621:A8C75 RS12245
gene id: 1821621:A8C75_RS12245
uniprot id: A0A1A9EZ38
names: Similarity
messages: Belongs to the allantoicase family.

1821621:A8C75 RS16900
gene id: 1821621:A8C75_RS16900
uniprot id: A0A1A9F285
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1821621:A8C75 RS01525
gene id: 1821621:A8C75_RS01525
uniprot id: A0A1A9EU56
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1821621:A8C75 RS02290
gene id: 1821621:A8C75_RS02290
uniprot id: A0A1A9EUU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1821621:A8C75 RS12365
gene id: 1821621:A8C75_RS12365
uniprot id: A0A1A9EZ13
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1821621:A8C75 RS07865
gene id: 1821621:A8C75_RS07865
uniprot id: A0A1A9EX69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1821621:A8C75 RS04245
gene id: 1821621:A8C75_RS04245
uniprot id: A0A1A9EUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1821621:A8C75 RS12950
gene id: 1821621:A8C75_RS12950
uniprot id: A0A1A9F0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1821621:A8C75 RS12985
gene id: 1821621:A8C75_RS12985
uniprot id: A0A1A9EZF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1821621:A8C75 RS02075
gene id: 1821621:A8C75_RS02075
uniprot id: A0A1A9EUF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1821621:A8C75 RS01465
gene id: 1821621:A8C75_RS01465
uniprot id: A0A1A9EUL0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1821621:A8C75 RS16775
gene id: 1821621:A8C75_RS16775
uniprot id: A0A1A9F251
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1821621:A8C75 RS05585
gene id: 1821621:A8C75_RS05585
uniprot id: A0A1A9EWK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1821621:A8C75 RS18095
gene id: 1821621:A8C75_RS18095
uniprot id: A0A1A9F209
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1821621:A8C75 RS01135
gene id: 1821621:A8C75_RS01135
uniprot id: A0A1A9ETL3
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1821621:A8C75 RS09320
gene id: 1821621:A8C75_RS09320
uniprot id: A0A1A9EYF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1821621:A8C75 RS12515
gene id: 1821621:A8C75_RS12515
uniprot id: A0A1A9EZ85
names: Similarity
messages: Belongs to the GST superfamily.

1821621:A8C75 RS03435
gene id: 1821621:A8C75_RS03435
uniprot id: A0A1A9EV56
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS17505
gene id: 1821621:A8C75_RS17505
uniprot id: A0A1A9F1P2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1821621:A8C75 RS18920
gene id: 1821621:A8C75_RS18920
uniprot id: A0A1A9F3A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS17550
gene id: 1821621:A8C75_RS17550
uniprot id: A0A1A9F1K3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1821621:A8C75 RS16380
gene id: 1821621:A8C75_RS16380
uniprot id: A0A1A9F108
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1821621:A8C75 RS05730
gene id: 1821621:A8C75_RS05730
uniprot id: A0A1A9EWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1821621:A8C75 RS02910
gene id: 1821621:A8C75_RS02910
uniprot id: A0A1A9EUF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS21380
gene id: 1821621:A8C75_RS21380
uniprot id: A0A1A9F3H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1821621:A8C75 RS09250
gene id: 1821621:A8C75_RS09250
uniprot id: A0A1A9EYP4
names: Similarity
messages: Belongs to the PrpD family.

1821621:A8C75 RS01685
gene id: 1821621:A8C75_RS01685
uniprot id: A0A1A9EUQ7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1821621:A8C75 RS14290
gene id: 1821621:A8C75_RS14290
uniprot id: A0A1A9F1B8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS18005
gene id: 1821621:A8C75_RS18005
uniprot id: A0A1A9F329
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS20490
gene id: 1821621:A8C75_RS20490
uniprot id: A0A1A9F320
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1821621:A8C75 RS11220
gene id: 1821621:A8C75_RS11220
uniprot id: A0A1A9EYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1821621:A8C75 RS00755
gene id: 1821621:A8C75_RS00755
uniprot id: A0A1A9F3Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS04970
gene id: 1821621:A8C75_RS04970
uniprot id: A0A1A9EWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1821621:A8C75 RS03830
gene id: 1821621:A8C75_RS03830
uniprot id: A0A1A9EV14
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1821621:A8C75 RS04725
gene id: 1821621:A8C75_RS04725
uniprot id: A0A1A9EWE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS04475
gene id: 1821621:A8C75_RS04475
uniprot id: A0A1A9EV88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1821621:A8C75 RS21155
gene id: 1821621:A8C75_RS21155
uniprot id: A0A1A9F3I1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1821621:A8C75 RS07625
gene id: 1821621:A8C75_RS07625
uniprot id: A0A1A9EXW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1821621:A8C75 RS05660
gene id: 1821621:A8C75_RS05660
uniprot id: A0A1A9EVW3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1821621:A8C75 RS01650
gene id: 1821621:A8C75_RS01650
uniprot id: A0A1A9EU32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1821621:A8C75 RS22265
gene id: 1821621:A8C75_RS22265
uniprot id: A0A1A9F5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1821621:A8C75 RS17270
gene id: 1821621:A8C75_RS17270
uniprot id: A0A1A9F1K1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1821621:A8C75 RS16795
gene id: 1821621:A8C75_RS16795
uniprot id: A0A1A9F1I8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1821621:A8C75 RS19460
gene id: 1821621:A8C75_RS19460
uniprot id: A0A1A9F2V7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1821621:A8C75 RS22290
gene id: 1821621:A8C75_RS22290
uniprot id: A0A1A9F3Y6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1821621:A8C75 RS12370
gene id: 1821621:A8C75_RS12370
uniprot id: A0A1A9EZ72
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS04880
gene id: 1821621:A8C75_RS04880
uniprot id: A0A1A9EWH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1821621:A8C75 RS11215
gene id: 1821621:A8C75_RS11215
uniprot id: A0A1A9EXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS09550
gene id: 1821621:A8C75_RS09550
uniprot id: A0A1A9EYZ0
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS12080
gene id: 1821621:A8C75_RS12080
uniprot id: A0A1A9EYV9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1821621:A8C75 RS06380
gene id: 1821621:A8C75_RS06380
uniprot id: A0A1A9EVF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1821621:A8C75 RS00130
gene id: 1821621:A8C75_RS00130
uniprot id: A0A1A9ESZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1821621:A8C75 RS05270
gene id: 1821621:A8C75_RS05270
uniprot id: A0A1A9EWP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1821621:A8C75 RS01755
gene id: 1821621:A8C75_RS01755
uniprot id: A0A1A9EUV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS22400
gene id: 1821621:A8C75_RS22400
uniprot id: A0A1A9F448
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1821621:A8C75 RS16980
gene id: 1821621:A8C75_RS16980
uniprot id: A0A1A9F1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1821621:A8C75 RS04955
gene id: 1821621:A8C75_RS04955
uniprot id: A0A1A9EVG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1821621:A8C75 RS01390
gene id: 1821621:A8C75_RS01390
uniprot id: A0A1A9ETN4
names: Similarity
messages: Belongs to the YggT family.

1821621:A8C75 RS11780
gene id: 1821621:A8C75_RS11780
uniprot id: A0A1A9EZ23
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1821621:A8C75 RS04280
gene id: 1821621:A8C75_RS04280
uniprot id: A0A1A9EVV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1821621:A8C75 RS15155
gene id: 1821621:A8C75_RS15155
uniprot id: A0A1A9F1T3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1821621:A8C75 RS21330
gene id: 1821621:A8C75_RS21330
uniprot id: A0A1A9F3G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1821621:A8C75 RS06130
gene id: 1821621:A8C75_RS06130
uniprot id: A0A1A9EWV5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1821621:A8C75 RS01555
gene id: 1821621:A8C75_RS01555
uniprot id: A0A1A9ETP1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1821621:A8C75 RS02030
gene id: 1821621:A8C75_RS02030
uniprot id: A0A1A9EUP3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1821621:A8C75 RS21255
gene id: 1821621:A8C75_RS21255
uniprot id: A0A1A9F3U6
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

1821621:A8C75 RS21845
gene id: 1821621:A8C75_RS21845
uniprot id: A0A1A9F530
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

1821621:A8C75 RS22120
gene id: 1821621:A8C75_RS22120
uniprot id: A0A1A9F3Z9
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1821621:A8C75 RS00370
gene id: 1821621:A8C75_RS00370
uniprot id: A0A1A9ETS7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1821621:A8C75 RS06930
gene id: 1821621:A8C75_RS06930
uniprot id: A0A1A9EX87
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1821621:A8C75 RS21810
gene id: 1821621:A8C75_RS21810
uniprot id: A0A1A9F455
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS01450
gene id: 1821621:A8C75_RS01450
uniprot id: A0A1A9ETL9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1821621:A8C75 RS09340
gene id: 1821621:A8C75_RS09340
uniprot id: A0A1A9EWZ7
names: Similarity
messages: Belongs to the fabD family.

1821621:A8C75 RS19780
gene id: 1821621:A8C75_RS19780
uniprot id: A0A1A9F403
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

1821621:A8C75 RS05060
gene id: 1821621:A8C75_RS05060
uniprot id: A0A1A9EVJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS03335
gene id: 1821621:A8C75_RS03335
uniprot id: A0A1A9EVE1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1821621:A8C75 RS15585
gene id: 1821621:A8C75_RS15585
uniprot id: A0A1A9F208
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS04365
gene id: 1821621:A8C75_RS04365
uniprot id: A0A1A9EV66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1821621:A8C75 RS09345
gene id: 1821621:A8C75_RS09345
uniprot id: A0A1A9EXQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1821621:A8C75 RS08120
gene id: 1821621:A8C75_RS08120
uniprot id: A0A1A9EX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1821621:A8C75 RS20185
gene id: 1821621:A8C75_RS20185
uniprot id: A0A1A9F3L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS20750
gene id: 1821621:A8C75_RS20750
uniprot id: A0A1A9F3B2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS19005
gene id: 1821621:A8C75_RS19005
uniprot id: A0A1A9F2A5
names: Similarity
messages: Belongs to the DapA family.

1821621:A8C75 RS00550
gene id: 1821621:A8C75_RS00550
uniprot id: A0A1A9ETM7
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1821621:A8C75 RS17500
gene id: 1821621:A8C75_RS17500
uniprot id: A0A1A9F1J3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS15395
gene id: 1821621:A8C75_RS15395
uniprot id: A0A1A9F0R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS00420
gene id: 1821621:A8C75_RS00420
uniprot id: A0A1A9ET77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1821621:A8C75 RS08700
gene id: 1821621:A8C75_RS08700
uniprot id: A0A1A9EXB5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1821621:A8C75 RS13185
gene id: 1821621:A8C75_RS13185
uniprot id: A0A1A9F0M1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS02060
gene id: 1821621:A8C75_RS02060
uniprot id: A0A1A9EU33
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1821621:A8C75 RS04010
gene id: 1821621:A8C75_RS04010
uniprot id: A0A1A9EVQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1821621:A8C75 RS18155
gene id: 1821621:A8C75_RS18155
uniprot id: A0A1A9F1I9
names: Subcellular Location Annotation
messages: Cytoplasm

1821621:A8C75 RS22015
gene id: 1821621:A8C75_RS22015
uniprot id: A0A1A9F4I3
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1821621:A8C75 RS03240
gene id: 1821621:A8C75_RS03240
uniprot id: A0A1A9EUK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1821621:A8C75 RS16460
gene id: 1821621:A8C75_RS16460
uniprot id: A0A1A9F1Z3
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1821621:A8C75 RS03715
gene id: 1821621:A8C75_RS03715
uniprot id: A0A1A9EU47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1821621:A8C75 RS02965
gene id: 1821621:A8C75_RS02965
uniprot id: A0A1A9EUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1821621:A8C75 RS00225
gene id: 1821621:A8C75_RS00225
uniprot id: A0A1A9ES78
names: Similarity
messages: Belongs to the Fur family.

1821621:A8C75 RS11795
gene id: 1821621:A8C75_RS11795
uniprot id: A0A1A9EY67
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1821621:A8C75 RS20725
gene id: 1821621:A8C75_RS20725
uniprot id: A0A1A9F3V8
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS02340
gene id: 1821621:A8C75_RS02340
uniprot id: A0A1A9EUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1821621:A8C75 RS05340
gene id: 1821621:A8C75_RS05340
uniprot id: A0A1A9EVN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1821621:A8C75 RS06215
gene id: 1821621:A8C75_RS06215
uniprot id: A0A1A9EW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1821621:A8C75 RS10780
gene id: 1821621:A8C75_RS10780
uniprot id: A0A1A9EZ37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1821621:A8C75 RS17390
gene id: 1821621:A8C75_RS17390
uniprot id: A0A1A9F2S0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1821621:A8C75 RS18550
gene id: 1821621:A8C75_RS18550
uniprot id: A0A1A9F2E5
names: Similarity
messages: Belongs to the CvfB family.

1821621:A8C75 RS12630
gene id: 1821621:A8C75_RS12630
uniprot id: A0A1A9F0F8
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1821621:A8C75 RS05290
gene id: 1821621:A8C75_RS05290
uniprot id: A0A1A9EVM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1821621:A8C75 RS08340
gene id: 1821621:A8C75_RS08340
uniprot id: A0A1A9EWH2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1821621:A8C75 RS02010
gene id: 1821621:A8C75_RS02010
uniprot id: A0A1A9EU24
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1821621:A8C75 RS08135
gene id: 1821621:A8C75_RS08135
uniprot id: A0A1A9EXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1821621:A8C75 RS14555
gene id: 1821621:A8C75_RS14555
uniprot id: A0A1A9EZS7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS06415
gene id: 1821621:A8C75_RS06415
uniprot id: A0A1A9EWZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1821621:A8C75 RS16175
gene id: 1821621:A8C75_RS16175
uniprot id: A0A1A9F272
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1821621:A8C75 RS13160
gene id: 1821621:A8C75_RS13160
uniprot id: A0A1A9EYY7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS01635
gene id: 1821621:A8C75_RS01635
uniprot id: A0A1A9EUP6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1821621:A8C75 RS02925
gene id: 1821621:A8C75_RS02925
uniprot id: A0A1A9EV47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1821621:A8C75 RS17485
gene id: 1821621:A8C75_RS17485
uniprot id: A0A1A9F2X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1821621:A8C75 RS03695
gene id: 1821621:A8C75_RS03695
uniprot id: A0A1A9EV78
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS13620
gene id: 1821621:A8C75_RS13620
uniprot id: A0A1A9EZY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS08355
gene id: 1821621:A8C75_RS08355
uniprot id: A0A1A9EXB2
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS21885
gene id: 1821621:A8C75_RS21885
uniprot id: A0A1A9F3R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1821621:A8C75 RS00365
gene id: 1821621:A8C75_RS00365
uniprot id: A0A1A9ET66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1821621:A8C75 RS04455
gene id: 1821621:A8C75_RS04455
uniprot id: A0A1A9EVH3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1821621:A8C75 RS17515
gene id: 1821621:A8C75_RS17515
uniprot id: A0A1A9F2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1821621:A8C75 RS03940
gene id: 1821621:A8C75_RS03940
uniprot id: A0A1A9EVY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS07500
gene id: 1821621:A8C75_RS07500
uniprot id: A0A1A9EXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS15970
gene id: 1821621:A8C75_RS15970
uniprot id: A0A1A9F153
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS17955
gene id: 1821621:A8C75_RS17955
uniprot id: A0A1A9F318
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1821621:A8C75 RS00245
gene id: 1821621:A8C75_RS00245
uniprot id: A0A1A9ET09
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS17875
gene id: 1821621:A8C75_RS17875
uniprot id: A0A1A9F1D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS18715
gene id: 1821621:A8C75_RS18715
uniprot id: A0A1A9F1U1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS19580
gene id: 1821621:A8C75_RS19580
uniprot id: A0A1A9F2L1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1821621:A8C75 RS22675
gene id: 1821621:A8C75_RS22675
uniprot id: A0A1A9F497
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS20680
gene id: 1821621:A8C75_RS20680
uniprot id: A0A1A9F478
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS20040
gene id: 1821621:A8C75_RS20040
uniprot id: A0A1A9F490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS12960
gene id: 1821621:A8C75_RS12960
uniprot id: A0A1A9EZW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1821621:A8C75 RS15015
gene id: 1821621:A8C75_RS15015
uniprot id: A0A1A9F0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS02625
gene id: 1821621:A8C75_RS02625
uniprot id: A0A1A9EUL2
names: Similarity
messages: Belongs to the UPF0250 family.

1821621:A8C75 RS20685
gene id: 1821621:A8C75_RS20685
uniprot id: A0A1A9F3J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS09420
gene id: 1821621:A8C75_RS09420
uniprot id: A0A1A9EY63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1821621:A8C75 RS22260
gene id: 1821621:A8C75_RS22260
uniprot id: A0A1A9F4D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1821621:A8C75 RS19655
gene id: 1821621:A8C75_RS19655
uniprot id: A0A1A9F2P3
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1821621:A8C75 RS17300
gene id: 1821621:A8C75_RS17300
uniprot id: A0A1A9F2U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1821621:A8C75 RS22205
gene id: 1821621:A8C75_RS22205
uniprot id: A0A1A9F4B9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1821621:A8C75 RS11340
gene id: 1821621:A8C75_RS11340
uniprot id: A0A1A9EXZ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1821621:A8C75 RS13520
gene id: 1821621:A8C75_RS13520
uniprot id: A0A1A9EZP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS05305
gene id: 1821621:A8C75_RS05305
uniprot id: A0A1A9EWP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1821621:A8C75 RS09280
gene id: 1821621:A8C75_RS09280
uniprot id: A0A1A9EWY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS22805
gene id: 1821621:A8C75_RS22805
uniprot id: A0A1A9F5J2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1821621:A8C75 RS05555
gene id: 1821621:A8C75_RS05555
uniprot id: A0A1A9EVU3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS04020
gene id: 1821621:A8C75_RS04020
uniprot id: A0A1A9EW22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1821621:A8C75 RS19190
gene id: 1821621:A8C75_RS19190
uniprot id: A0A1A9F238
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1821621:A8C75 RS08760
gene id: 1821621:A8C75_RS08760
uniprot id: A0A1A9EXC5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1821621:A8C75 RS19815
gene id: 1821621:A8C75_RS19815
uniprot id: A0A1A9F2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1821621:A8C75 RS06360
gene id: 1821621:A8C75_RS06360
uniprot id: A0A1A9EWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1821621:A8C75 RS13415
gene id: 1821621:A8C75_RS13415
uniprot id: A0A1A9F0G2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1821621:A8C75 RS19870
gene id: 1821621:A8C75_RS19870
uniprot id: A0A1A9F5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1821621:A8C75 RS09230
gene id: 1821621:A8C75_RS09230
uniprot id: A0A1A9EXM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1821621:A8C75 RS03025
gene id: 1821621:A8C75_RS03025
uniprot id: A0A1A9EUN1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1821621:A8C75 RS02375
gene id: 1821621:A8C75_RS02375
uniprot id: A0A1A9EU42
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1821621:A8C75 RS14325
gene id: 1821621:A8C75_RS14325
uniprot id: A0A1A9F0K9
names: Similarity
messages: Belongs to the universal stress protein A family.

1821621:A8C75 RS14070
gene id: 1821621:A8C75_RS14070
uniprot id: A0A1A9EZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1821621:A8C75 RS07690
gene id: 1821621:A8C75_RS07690
uniprot id: A0A1A9EX40
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1821621:A8C75 RS03445
gene id: 1821621:A8C75_RS03445
uniprot id: A0A1A9EV05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1821621:A8C75 RS19160
gene id: 1821621:A8C75_RS19160
uniprot id: A0A1A9F3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1821621:A8C75 RS01665
gene id: 1821621:A8C75_RS01665
uniprot id: A0A1A9ETT3
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS16275
gene id: 1821621:A8C75_RS16275
uniprot id: A0A1A9F142
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS04520
gene id: 1821621:A8C75_RS04520
uniprot id: A0A1A9EWB0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1821621:A8C75 RS15700
gene id: 1821621:A8C75_RS15700
uniprot id: A0A1A9F0A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS18760
gene id: 1821621:A8C75_RS18760
uniprot id: A0A1A9F3J9
names: Similarity
messages: Belongs to the leucine-binding protein family.

1821621:A8C75 RS17940
gene id: 1821621:A8C75_RS17940
uniprot id: A0A1A9F1R4
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS22100
gene id: 1821621:A8C75_RS22100
uniprot id: A0A1A9F4X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS22760
gene id: 1821621:A8C75_RS22760
uniprot id: A0A1A9F4W6
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS21370
gene id: 1821621:A8C75_RS21370
uniprot id: A0A1A9F384
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1821621:A8C75 RS07205
gene id: 1821621:A8C75_RS07205
uniprot id: A0A1A9EX28
names: Similarity
messages: Belongs to the MlaA family.

1821621:A8C75 RS21460
gene id: 1821621:A8C75_RS21460
uniprot id: A0A1A9F4L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1821621:A8C75 RS11405
gene id: 1821621:A8C75_RS11405
uniprot id: A0A1A9EZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1821621:A8C75 RS16445
gene id: 1821621:A8C75_RS16445
uniprot id: A0A1A9F202
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1821621:A8C75 RS09890
gene id: 1821621:A8C75_RS09890
uniprot id: A0A1A9EZ01
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1821621:A8C75 RS14800
gene id: 1821621:A8C75_RS14800
uniprot id: A0A1A9F0F1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS19720
gene id: 1821621:A8C75_RS19720
uniprot id: A0A1A9F2Q0
names: Subcellular Location Annotation
messages: Cell inner membrane

1821621:A8C75 RS04845
gene id: 1821621:A8C75_RS04845
uniprot id: A0A1A9EVL4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1821621:A8C75 RS03810
gene id: 1821621:A8C75_RS03810
uniprot id: A0A1A9EVY3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS19215
gene id: 1821621:A8C75_RS19215
uniprot id: A0A1A9F3C5
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1821621:A8C75 RS21940
gene id: 1821621:A8C75_RS21940
uniprot id: A0A1A9F3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
messages: Cytoplasm

1821621:A8C75 RS13980
gene id: 1821621:A8C75_RS13980
uniprot id: A0A1A9F123
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1821621:A8C75 RS20465
gene id: 1821621:A8C75_RS20465
uniprot id: A0A1A9F435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1821621:A8C75 RS19525
gene id: 1821621:A8C75_RS19525
uniprot id: A0A1A9F2P9
names: Similarity
messages: Belongs to the UxaA family.

1821621:A8C75 RS09785
gene id: 1821621:A8C75_RS09785
uniprot id: A0A1A9EY47
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

1821621:A8C75 RS07100
gene id: 1821621:A8C75_RS07100
uniprot id: A0A1A9EXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1821621:A8C75 RS08145
gene id: 1821621:A8C75_RS08145
uniprot id: A0A1A9EXJ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1821621:A8C75 RS01990
gene id: 1821621:A8C75_RS01990
uniprot id: A0A1A9EUY9
names: Similarity
messages: Belongs to the glutamate synthase family.

1821621:A8C75 RS06420
gene id: 1821621:A8C75_RS06420
uniprot id: A0A1A9EWH1
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1821621:A8C75 RS07615
gene id: 1821621:A8C75_RS07615
uniprot id: A0A1A9EWY6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1821621:A8C75 RS18800
gene id: 1821621:A8C75_RS18800
uniprot id: A0A1A9F2V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS01655
gene id: 1821621:A8C75_RS01655
uniprot id: A0A1A9EUT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1821621:A8C75 RS13565
gene id: 1821621:A8C75_RS13565
uniprot id: A0A1A9F0X4
names: Similarity
messages: Belongs to the class-I fumarase family.

1821621:A8C75 RS21300
gene id: 1821621:A8C75_RS21300
uniprot id: A0A1A9F454
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1821621:A8C75 RS13555
gene id: 1821621:A8C75_RS13555
uniprot id: A0A1A9EZX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS22435
gene id: 1821621:A8C75_RS22435
uniprot id: A0A1A9F4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS14275
gene id: 1821621:A8C75_RS14275
uniprot id: A0A1A9F0J9
names: Similarity
messages: Belongs to the RutC family.

1821621:A8C75 RS15625
gene id: 1821621:A8C75_RS15625
uniprot id: A0A1A9F1K0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1821621:A8C75 RS05560
gene id: 1821621:A8C75_RS05560
uniprot id: A0A1A9EVS1
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1821621:A8C75 RS09430
gene id: 1821621:A8C75_RS09430
uniprot id: A0A1A9EXY8
names: Similarity
messages: Belongs to the DsrF/TusC family.

1821621:A8C75 RS15170
gene id: 1821621:A8C75_RS15170
uniprot id: A0A1A9F0F9
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

1821621:A8C75 RS12900
gene id: 1821621:A8C75_RS12900
uniprot id: A0A1A9F0H6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS01795
gene id: 1821621:A8C75_RS01795
uniprot id: A0A1A9EUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS07820
gene id: 1821621:A8C75_RS07820
uniprot id: A0A1A9EW82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1821621:A8C75 RS12315
gene id: 1821621:A8C75_RS12315
uniprot id: A0A1A9EZ62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS00635
gene id: 1821621:A8C75_RS00635
uniprot id: A0A1A9ET79
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS04115
gene id: 1821621:A8C75_RS04115
uniprot id: A0A1A9EW11
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1821621:A8C75 RS12810
gene id: 1821621:A8C75_RS12810
uniprot id: A0A1A9F0I1
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1821621:A8C75 RS01840
gene id: 1821621:A8C75_RS01840
uniprot id: A0A1A9ETU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1821621:A8C75 RS02975
gene id: 1821621:A8C75_RS02975
uniprot id: A0A1A9EUM3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS09115
gene id: 1821621:A8C75_RS09115
uniprot id: A0A1A9EXI4
names: Similarity
messages: Belongs to the nitroreductase family.

1821621:A8C75 RS00425
gene id: 1821621:A8C75_RS00425
uniprot id: A0A1A9ETT6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS14530
gene id: 1821621:A8C75_RS14530
uniprot id: A0A1A9F1D4
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1821621:A8C75 RS16915
gene id: 1821621:A8C75_RS16915
uniprot id: A0A1A9F0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS21610
gene id: 1821621:A8C75_RS21610
uniprot id: A0A1A9F3L3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1821621:A8C75 RS02465
gene id: 1821621:A8C75_RS02465
uniprot id: A0A1A9ETG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1821621:A8C75 RS05265
gene id: 1821621:A8C75_RS05265
uniprot id: A0A1A9EVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1821621:A8C75 RS03775
gene id: 1821621:A8C75_RS03775
uniprot id: A0A1A9EUU2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1821621:A8C75 RS03705
gene id: 1821621:A8C75_RS03705
uniprot id: A0A1A9EV45
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1821621:A8C75 RS18705
gene id: 1821621:A8C75_RS18705
uniprot id: A0A1A9F2H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1821621:A8C75 RS06155
gene id: 1821621:A8C75_RS06155
uniprot id: A0A1A9EVB5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1821621:A8C75 RS04275
gene id: 1821621:A8C75_RS04275
uniprot id: A0A1A9EVJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1821621:A8C75 RS09615
gene id: 1821621:A8C75_RS09615
uniprot id: A0A1A9EYZ9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1821621:A8C75 RS22410
gene id: 1821621:A8C75_RS22410
uniprot id: A0A1A9F407
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1821621:A8C75 RS01580
gene id: 1821621:A8C75_RS01580
uniprot id: A0A1A9EU67
names: Similarity
messages: Belongs to the YkuD family.

1821621:A8C75 RS04300
gene id: 1821621:A8C75_RS04300
uniprot id: A0A1A9EUE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1821621:A8C75 RS13615
gene id: 1821621:A8C75_RS13615
uniprot id: A0A1A9F0H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS03995
gene id: 1821621:A8C75_RS03995
uniprot id: A0A1A9EVM3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS19045
gene id: 1821621:A8C75_RS19045
uniprot id: A0A1A9F205
names: Similarity
messages: Belongs to the asparaginase 1 family.

1821621:A8C75 RS06445
gene id: 1821621:A8C75_RS06445
uniprot id: A0A1A9EWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS16740
gene id: 1821621:A8C75_RS16740
uniprot id: A0A1A9F1H8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS01405
gene id: 1821621:A8C75_RS01405
uniprot id: A0A1A9EUB5
names: Similarity
messages: Belongs to the GSP E family.

1821621:A8C75 RS05550
gene id: 1821621:A8C75_RS05550
uniprot id: A0A1A9EV19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1821621:A8C75 RS16030
gene id: 1821621:A8C75_RS16030
uniprot id: A0A1A9F267
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS21710
gene id: 1821621:A8C75_RS21710
uniprot id: A0A1A9F434
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1821621:A8C75 RS20595
gene id: 1821621:A8C75_RS20595
uniprot id: A0A1A9F339
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1821621:A8C75 RS10520
gene id: 1821621:A8C75_RS10520
uniprot id: A0A1A9EYG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1821621:A8C75 RS05375
gene id: 1821621:A8C75_RS05375
uniprot id: A0A1A9EVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS16655
gene id: 1821621:A8C75_RS16655
uniprot id: A0A1A9F231
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1821621:A8C75 RS02320
gene id: 1821621:A8C75_RS02320
uniprot id: A0A1A9EU85
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS18200
gene id: 1821621:A8C75_RS18200
uniprot id: A0A1A9F3A0
names: Similarity
messages: Belongs to the asparaginase 1 family.

1821621:A8C75 RS19380
gene id: 1821621:A8C75_RS19380
uniprot id: A0A1A9F370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS17170
gene id: 1821621:A8C75_RS17170
uniprot id: A0A1A9F216
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1821621:A8C75 RS01745
gene id: 1821621:A8C75_RS01745
uniprot id: A0A1A9EUJ0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1821621:A8C75 RS01000
gene id: 1821621:A8C75_RS01000
uniprot id: A0A1A9ETR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1821621:A8C75 RS04830
gene id: 1821621:A8C75_RS04830
uniprot id: A0A1A9EUN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS03485
gene id: 1821621:A8C75_RS03485
uniprot id: A0A1A9EUP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS02610
gene id: 1821621:A8C75_RS02610
uniprot id: A0A1A9EUQ8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1821621:A8C75 RS09935
gene id: 1821621:A8C75_RS09935
uniprot id: A0A1A9EY08
names: Similarity
messages: Belongs to the nitroreductase family.

1821621:A8C75 RS03155
gene id: 1821621:A8C75_RS03155
uniprot id: A0A1A9EVB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1821621:A8C75 RS05330
gene id: 1821621:A8C75_RS05330
uniprot id: A0A1A9EUX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1821621:A8C75 RS17860
gene id: 1821621:A8C75_RS17860
uniprot id: A0A1A9F2R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS08620
gene id: 1821621:A8C75_RS08620
uniprot id: A0A1A9EYH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1821621:A8C75 RS02410
gene id: 1821621:A8C75_RS02410
uniprot id: A0A1A9EV73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS02485
gene id: 1821621:A8C75_RS02485
uniprot id: A0A1A9EUW6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1821621:A8C75 RS14595
gene id: 1821621:A8C75_RS14595
uniprot id: A0A1A9F0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1821621:A8C75 RS05855
gene id: 1821621:A8C75_RS05855
uniprot id: A0A1A9EV68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1821621:A8C75 RS22700
gene id: 1821621:A8C75_RS22700
uniprot id: A0A1A9F5H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1821621:A8C75 RS12095
gene id: 1821621:A8C75_RS12095
uniprot id: A0A1A9EZS3
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS00125
gene id: 1821621:A8C75_RS00125
uniprot id: A0A1A9ESZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1821621:A8C75 RS14075
gene id: 1821621:A8C75_RS14075
uniprot id: A0A1A9F5M9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1821621:A8C75 RS08465
gene id: 1821621:A8C75_RS08465
uniprot id: A0A1A9EXD4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1821621:A8C75 RS01660
gene id: 1821621:A8C75_RS01660
uniprot id: A0A1A9ET03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1821621:A8C75 RS09855
gene id: 1821621:A8C75_RS09855
uniprot id: A0A1A9EZ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS17945
gene id: 1821621:A8C75_RS17945
uniprot id: A0A1A9F1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1821621:A8C75 RS04745
gene id: 1821621:A8C75_RS04745
uniprot id: A0A1A9EVI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1821621:A8C75 RS02035
gene id: 1821621:A8C75_RS02035
uniprot id: A0A1A9EUA4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1821621:A8C75 RS16145
gene id: 1821621:A8C75_RS16145
uniprot id: A0A1A9F293
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1821621:A8C75 RS02805
gene id: 1821621:A8C75_RS02805
uniprot id: A0A1A9EUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1821621:A8C75 RS07120
gene id: 1821621:A8C75_RS07120
uniprot id: A0A1A9EWN0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1821621:A8C75 RS07230
gene id: 1821621:A8C75_RS07230
uniprot id: A0A1A9EWQ2
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS19570
gene id: 1821621:A8C75_RS19570
uniprot id: A0A1A9F2B0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS17480
gene id: 1821621:A8C75_RS17480
uniprot id: A0A1A9F1V8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1821621:A8C75 RS21785
gene id: 1821621:A8C75_RS21785
uniprot id: A0A1A9F3Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1821621:A8C75 RS16585
gene id: 1821621:A8C75_RS16585
uniprot id: A0A1A9F184
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

1821621:A8C75 RS20275
gene id: 1821621:A8C75_RS20275
uniprot id: A0A1A9F307
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1821621:A8C75 RS18515
gene id: 1821621:A8C75_RS18515
uniprot id: A0A1A9F210
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1821621:A8C75 RS04080
gene id: 1821621:A8C75_RS04080
uniprot id: A0A1A9EW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1821621:A8C75 RS20080
gene id: 1821621:A8C75_RS20080
uniprot id: A0A1A9F3W7
names: Similarity
messages: Belongs to the bacterial secretin family.

1821621:A8C75 RS05930
gene id: 1821621:A8C75_RS05930
uniprot id: A0A1A9EVY8
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS13880
gene id: 1821621:A8C75_RS13880
uniprot id: A0A1A9F0M6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1821621:A8C75 RS21400
gene id: 1821621:A8C75_RS21400
uniprot id: A0A1A9F474
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1821621:A8C75 RS05080
gene id: 1821621:A8C75_RS05080
uniprot id: A0A1A9EVZ6
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1821621:A8C75 RS01670
gene id: 1821621:A8C75_RS01670
uniprot id: A0A1A9ETR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1821621:A8C75 RS00990
gene id: 1821621:A8C75_RS00990
uniprot id: A0A1A9ETV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1821621:A8C75 RS01930
gene id: 1821621:A8C75_RS01930
uniprot id: A0A1A9EUX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1821621:A8C75 RS03195
gene id: 1821621:A8C75_RS03195
uniprot id: A0A1A9EV92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS11855
gene id: 1821621:A8C75_RS11855
uniprot id: A0A1A9EYX5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1821621:A8C75 RS04490
gene id: 1821621:A8C75_RS04490
uniprot id: A0A1A9F4V5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1821621:A8C75 RS19635
gene id: 1821621:A8C75_RS19635
uniprot id: A0A1A9F413
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1821621:A8C75 RS12835
gene id: 1821621:A8C75_RS12835
uniprot id: A0A1A9EZF4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS07200
gene id: 1821621:A8C75_RS07200
uniprot id: A0A1A9EXP2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1821621:A8C75 RS01215
gene id: 1821621:A8C75_RS01215
uniprot id: A0A1A9ETU9
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1821621:A8C75 RS06065
gene id: 1821621:A8C75_RS06065
uniprot id: A0A1A9EX32
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1821621:A8C75 RS17140
gene id: 1821621:A8C75_RS17140
uniprot id: A0A1A9F100
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1821621:A8C75 RS21500
gene id: 1821621:A8C75_RS21500
uniprot id: A0A1A9F4W9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1821621:A8C75 RS03305
gene id: 1821621:A8C75_RS03305
uniprot id: A0A1A9EUL9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS21480
gene id: 1821621:A8C75_RS21480
uniprot id: A0A1A9F3P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1821621:A8C75 RS00655
gene id: 1821621:A8C75_RS00655
uniprot id: A0A1A9ETP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS03325
gene id: 1821621:A8C75_RS03325
uniprot id: A0A1A9EVM8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1821621:A8C75 RS02135
gene id: 1821621:A8C75_RS02135
uniprot id: A0A1A9EUR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1821621:A8C75 RS03455
gene id: 1821621:A8C75_RS03455
uniprot id: A0A1A9EU08
names: Similarity
messages: Belongs to the aspartokinase family.

1821621:A8C75 RS14035
gene id: 1821621:A8C75_RS14035
uniprot id: A0A1A9F139
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1821621:A8C75 RS20715
gene id: 1821621:A8C75_RS20715
uniprot id: A0A1A9F442
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1821621:A8C75 RS15065
gene id: 1821621:A8C75_RS15065
uniprot id: A0A1A9F0D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1821621:A8C75 RS18365
gene id: 1821621:A8C75_RS18365
uniprot id: A0A1A9F2B9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS05850
gene id: 1821621:A8C75_RS05850
uniprot id: A0A1A9EX01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1821621:A8C75 RS17195
gene id: 1821621:A8C75_RS17195
uniprot id: A0A1A9F111
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1821621:A8C75 RS21670
gene id: 1821621:A8C75_RS21670
uniprot id: A0A1A9F3R8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1821621:A8C75 RS04375
gene id: 1821621:A8C75_RS04375
uniprot id: A0A1A9EVV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1821621:A8C75 RS00100
gene id: 1821621:A8C75_RS00100
uniprot id: A0A1A9ETD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1821621:A8C75 RS11765
gene id: 1821621:A8C75_RS11765
uniprot id: A0A1A9EZY1
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1821621:A8C75 RS06265
gene id: 1821621:A8C75_RS06265
uniprot id: A0A1A9EW81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1821621:A8C75 RS03755
gene id: 1821621:A8C75_RS03755
uniprot id: A0A1A9EV50
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1821621:A8C75 RS11110
gene id: 1821621:A8C75_RS11110
uniprot id: A0A1A9EYL7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS16075
gene id: 1821621:A8C75_RS16075
uniprot id: A0A1A9F1G6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS21405
gene id: 1821621:A8C75_RS21405
uniprot id: A0A1A9F4K2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1821621:A8C75 RS00760
gene id: 1821621:A8C75_RS00760
uniprot id: A0A1A9EU79
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS09455
gene id: 1821621:A8C75_RS09455
uniprot id: A0A1A9EXP0
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1821621:A8C75 RS22465
gene id: 1821621:A8C75_RS22465
uniprot id: A0A1A9F506
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1821621:A8C75 RS04570
gene id: 1821621:A8C75_RS04570
uniprot id: A0A1A9EWC1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1821621:A8C75 RS10035
gene id: 1821621:A8C75_RS10035
uniprot id: A0A1A9EXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS16875
gene id: 1821621:A8C75_RS16875
uniprot id: A0A1A9F187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1821621:A8C75 RS21995
gene id: 1821621:A8C75_RS21995
uniprot id: A0A1A9F3U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1821621:A8C75 RS05390
gene id: 1821621:A8C75_RS05390
uniprot id: A0A1A9EVR5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1821621:A8C75 RS15930
gene id: 1821621:A8C75_RS15930
uniprot id: A0A1A9F0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS04420
gene id: 1821621:A8C75_RS04420
uniprot id: A0A1A9EV71
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1821621:A8C75 RS11665
gene id: 1821621:A8C75_RS11665
uniprot id: A0A1A9EZY6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1821621:A8C75 RS07605
gene id: 1821621:A8C75_RS07605
uniprot id: A0A1A9F4I8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1821621:A8C75 RS04555
gene id: 1821621:A8C75_RS04555
uniprot id: A0A1A9EVP1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1821621:A8C75 RS21205
gene id: 1821621:A8C75_RS21205
uniprot id: A0A1A9F351
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1821621:A8C75 RS05480
gene id: 1821621:A8C75_RS05480
uniprot id: A0A1A9EW68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1821621:A8C75 RS03955
gene id: 1821621:A8C75_RS03955
uniprot id: A0A1A9EV91
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1821621:A8C75 RS11310
gene id: 1821621:A8C75_RS11310
uniprot id: A0A1A9EZE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS04995
gene id: 1821621:A8C75_RS04995
uniprot id: A0A1A9EWJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1821621:A8C75 RS20290
gene id: 1821621:A8C75_RS20290
uniprot id: A0A1A9F3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS10085
gene id: 1821621:A8C75_RS10085
uniprot id: A0A1A9EY23
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1821621:A8C75 RS05020
gene id: 1821621:A8C75_RS05020
uniprot id: A0A1A9EW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1821621:A8C75 RS05515
gene id: 1821621:A8C75_RS05515
uniprot id: A0A1A9EVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1821621:A8C75 RS01540
gene id: 1821621:A8C75_RS01540
uniprot id: A0A1A9F0J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS21520
gene id: 1821621:A8C75_RS21520
uniprot id: A0A1A9F485
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1821621:A8C75 RS00410
gene id: 1821621:A8C75_RS00410
uniprot id: A0A1A9ET44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1821621:A8C75 RS13810
gene id: 1821621:A8C75_RS13810
uniprot id: A0A1A9F0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS07320
gene id: 1821621:A8C75_RS07320
uniprot id: A0A1A9EWX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1821621:A8C75 RS18160
gene id: 1821621:A8C75_RS18160
uniprot id: A0A1A9F219
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1821621:A8C75 RS21240
gene id: 1821621:A8C75_RS21240
uniprot id: A0A1A9F696
names: Similarity
messages: Belongs to the pyruvate kinase family.

1821621:A8C75 RS11320
gene id: 1821621:A8C75_RS11320
uniprot id: A0A1A9EZ50
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS02505
gene id: 1821621:A8C75_RS02505
uniprot id: A0A1A9EUZ1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1821621:A8C75 RS14890
gene id: 1821621:A8C75_RS14890
uniprot id: A0A1A9F1N3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS07740
gene id: 1821621:A8C75_RS07740
uniprot id: A0A1A9EXB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS04940
gene id: 1821621:A8C75_RS04940
uniprot id: A0A1A9EWI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1821621:A8C75 RS01715
gene id: 1821621:A8C75_RS01715
uniprot id: A0A1A9ETU6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS10940
gene id: 1821621:A8C75_RS10940
uniprot id: A0A1A9EZ76
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS13030
gene id: 1821621:A8C75_RS13030
uniprot id: A0A1A9F4U8
names: Subcellular Location Annotation
messages: Cytoplasm

1821621:A8C75 RS22155
gene id: 1821621:A8C75_RS22155
uniprot id: A0A1A9F4A9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS15635
gene id: 1821621:A8C75_RS15635
uniprot id: A0A1A9F211
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS02025
gene id: 1821621:A8C75_RS02025
uniprot id: A0A1A9EUE2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1821621:A8C75 RS15315
gene id: 1821621:A8C75_RS15315
uniprot id: A0A1A9F0U3
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1821621:A8C75 RS08160
gene id: 1821621:A8C75_RS08160
uniprot id: A0A1A9EY73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1821621:A8C75 RS22135
gene id: 1821621:A8C75_RS22135
uniprot id: A0A1A9F4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1821621:A8C75 RS13410
gene id: 1821621:A8C75_RS13410
uniprot id: A0A1A9EZQ1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1821621:A8C75 RS15030
gene id: 1821621:A8C75_RS15030
uniprot id: A0A1A9F1N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1821621:A8C75 RS17025
gene id: 1821621:A8C75_RS17025
uniprot id: A0A1A9F0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1821621:A8C75 RS03505
gene id: 1821621:A8C75_RS03505
uniprot id: A0A1A9EV61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS17455
gene id: 1821621:A8C75_RS17455
uniprot id: A0A1A9F1M5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1821621:A8C75 RS18580
gene id: 1821621:A8C75_RS18580
uniprot id: A0A1A9F264
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1821621:A8C75 RS21685
gene id: 1821621:A8C75_RS21685
uniprot id: A0A1A9F4L4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1821621:A8C75 RS18150
gene id: 1821621:A8C75_RS18150
uniprot id: A0A1A9F390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1821621:A8C75 RS20550
gene id: 1821621:A8C75_RS20550
uniprot id: A0A1A9F414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS09700
gene id: 1821621:A8C75_RS09700
uniprot id: A0A1A9EYJ5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1821621:A8C75 RS22460
gene id: 1821621:A8C75_RS22460
uniprot id: A0A1A9F419
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1821621:A8C75 RS05590
gene id: 1821621:A8C75_RS05590
uniprot id: A0A1A9EW28
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

1821621:A8C75 RS21560
gene id: 1821621:A8C75_RS21560
uniprot id: A0A1A9F3K0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1821621:A8C75 RS01395
gene id: 1821621:A8C75_RS01395
uniprot id: A0A1A9ETK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1821621:A8C75 RS22795
gene id: 1821621:A8C75_RS22795
uniprot id: A0A1A9F477
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS03600
gene id: 1821621:A8C75_RS03600
uniprot id: A0A1A9EUS0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1821621:A8C75 RS15200
gene id: 1821621:A8C75_RS15200
uniprot id: A0A1A9F1C5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1821621:A8C75 RS01730
gene id: 1821621:A8C75_RS01730
uniprot id: A0A1A9EUH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS01590
gene id: 1821621:A8C75_RS01590
uniprot id: A0A1A9EU22
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS04030
gene id: 1821621:A8C75_RS04030
uniprot id: A0A1A9EUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1821621:A8C75 RS16820
gene id: 1821621:A8C75_RS16820
uniprot id: A0A1A9F1D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1821621:A8C75 RS07700
gene id: 1821621:A8C75_RS07700
uniprot id: A0A1A9EW60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1821621:A8C75 RS16355
gene id: 1821621:A8C75_RS16355
uniprot id: A0A1A9F1X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1821621:A8C75 RS18815
gene id: 1821621:A8C75_RS18815
uniprot id: A0A1A9F2J8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1821621:A8C75 RS06315
gene id: 1821621:A8C75_RS06315
uniprot id: A0A1A9EVE4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1821621:A8C75 RS15345
gene id: 1821621:A8C75_RS15345
uniprot id: A0A1A9F0Q4
names: Similarity
messages: Belongs to the CFA/CMAS family.

1821621:A8C75 RS17930
gene id: 1821621:A8C75_RS17930
uniprot id: A0A1A9F1F0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1821621:A8C75 RS12595
gene id: 1821621:A8C75_RS12595
uniprot id: A0A1A9F013
names: Subcellular Location Annotation
messages: Cytoplasm

1821621:A8C75 RS02130
gene id: 1821621:A8C75_RS02130
uniprot id: A0A1A9EUG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1821621:A8C75 RS05250
gene id: 1821621:A8C75_RS05250
uniprot id: A0A1A9EWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1821621:A8C75 RS02050
gene id: 1821621:A8C75_RS02050
uniprot id: A0A1A9EU04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS01115
gene id: 1821621:A8C75_RS01115
uniprot id: A0A1A9EUH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1821621:A8C75 RS11045
gene id: 1821621:A8C75_RS11045
uniprot id: A0A1A9EXU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1821621:A8C75 RS00630
gene id: 1821621:A8C75_RS00630
uniprot id: A0A1A9ET86
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1821621:A8C75 RS05040
gene id: 1821621:A8C75_RS05040
uniprot id: A0A1A9EVS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1821621:A8C75 RS14420
gene id: 1821621:A8C75_RS14420
uniprot id: A0A1A9F112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS22165
gene id: 1821621:A8C75_RS22165
uniprot id: A0A1A9F3L5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1821621:A8C75 RS12670
gene id: 1821621:A8C75_RS12670
uniprot id: A0A1A9F023
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

1821621:A8C75 RS02500
gene id: 1821621:A8C75_RS02500
uniprot id: A0A1A9EUN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1821621:A8C75 RS07890
gene id: 1821621:A8C75_RS07890
uniprot id: A0A1A9EX38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1821621:A8C75 RS04065
gene id: 1821621:A8C75_RS04065
uniprot id: A0A1A9EVE6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1821621:A8C75 RS10175
gene id: 1821621:A8C75_RS10175
uniprot id: A0A1A9EZA1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS21550
gene id: 1821621:A8C75_RS21550
uniprot id: A0A1A9F3B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS06660
gene id: 1821621:A8C75_RS06660
uniprot id: A0A1A9EWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS20865
gene id: 1821621:A8C75_RS20865
uniprot id: A0A1A9F3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS16725
gene id: 1821621:A8C75_RS16725
uniprot id: A0A1A9F2F8
names: Subcellular Location Annotation
messages: Cytoplasm

1821621:A8C75 RS17175
gene id: 1821621:A8C75_RS17175
uniprot id: A0A1A9F2E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1821621:A8C75 RS07595
gene id: 1821621:A8C75_RS07595
uniprot id: A0A1A9EW40
names: Similarity
messages: Belongs to the PhzF family.

1821621:A8C75 RS13540
gene id: 1821621:A8C75_RS13540
uniprot id: A0A1A9F0U4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS16995
gene id: 1821621:A8C75_RS16995
uniprot id: A0A1A9F288
names: PTM
messages: Binds 1 heme group per subunit.

1821621:A8C75 RS04410
gene id: 1821621:A8C75_RS04410
uniprot id: A0A1A9EUG2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1821621:A8C75 RS03540
gene id: 1821621:A8C75_RS03540
uniprot id: A0A1A9EUW4
names: Similarity
messages: Belongs to the histone deacetylase family.

1821621:A8C75 RS04485
gene id: 1821621:A8C75_RS04485
uniprot id: A0A1A9EVE2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1821621:A8C75 RS10600
gene id: 1821621:A8C75_RS10600
uniprot id: A0A1A9EYC8
names: Similarity
messages: Belongs to the creatininase superfamily.

1821621:A8C75 RS19165
gene id: 1821621:A8C75_RS19165
uniprot id: A0A1A9F3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1821621:A8C75 RS20145
gene id: 1821621:A8C75_RS20145
uniprot id: A0A1A9F4B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS14295
gene id: 1821621:A8C75_RS14295
uniprot id: A0A1A9EZM7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1821621:A8C75 RS19080
gene id: 1821621:A8C75_RS19080
uniprot id: A0A1A9F3D4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1821621:A8C75 RS04135
gene id: 1821621:A8C75_RS04135
uniprot id: A0A1A9EW46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS07470
gene id: 1821621:A8C75_RS07470
uniprot id: A0A1A9EXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1821621:A8C75 RS20960
gene id: 1821621:A8C75_RS20960
uniprot id: A0A1A9F3Z5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1821621:A8C75 RS04025
gene id: 1821621:A8C75_RS04025
uniprot id: A0A1A9EUA1
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1821621:A8C75 RS21040
gene id: 1821621:A8C75_RS21040
uniprot id: A0A1A9F6K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1821621:A8C75 RS22535
gene id: 1821621:A8C75_RS22535
uniprot id: A0A1A9F4S2
names: Similarity
messages: Belongs to the glutamate synthase family.

1821621:A8C75 RS14310
gene id: 1821621:A8C75_RS14310
uniprot id: A0A1A9F061
names: Similarity
messages: Belongs to the TlyA family.

1821621:A8C75 RS20830
gene id: 1821621:A8C75_RS20830
uniprot id: A0A1A9F4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1821621:A8C75 RS06180
gene id: 1821621:A8C75_RS06180
uniprot id: A0A1A9EX57
names: Similarity
messages: Belongs to the HesB/IscA family.

1821621:A8C75 RS07805
gene id: 1821621:A8C75_RS07805
uniprot id: A0A1A9EX60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1821621:A8C75 RS12210
gene id: 1821621:A8C75_RS12210
uniprot id: A0A1A9F059
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1821621:A8C75 RS09390
gene id: 1821621:A8C75_RS09390
uniprot id: A0A1A9EX04
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1821621:A8C75 RS18215
gene id: 1821621:A8C75_RS18215
uniprot id: A0A1A9F223
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1821621:A8C75 RS00575
gene id: 1821621:A8C75_RS00575
uniprot id: A0A1A9ET75
names: Similarity
messages: Belongs to the P(II) protein family.

1821621:A8C75 RS17530
gene id: 1821621:A8C75_RS17530
uniprot id: A0A1A9F1W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1821621:A8C75 RS07770
gene id: 1821621:A8C75_RS07770
uniprot id: A0A1A9EWV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1821621:A8C75 RS12865
gene id: 1821621:A8C75_RS12865
uniprot id: A0A1A9F0J8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1821621:A8C75 RS18860
gene id: 1821621:A8C75_RS18860
uniprot id: A0A1A9F2W5
names: Similarity
messages: Belongs to the PrpF family.

1821621:A8C75 RS06385
gene id: 1821621:A8C75_RS06385
uniprot id: A0A1A9EW99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1821621:A8C75 RS04285
gene id: 1821621:A8C75_RS04285
uniprot id: A0A1A9F5C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1821621:A8C75 RS15905
gene id: 1821621:A8C75_RS15905
uniprot id: A0A1A9F145
names: Similarity
messages: Belongs to the UxaA family.

1821621:A8C75 RS07405
gene id: 1821621:A8C75_RS07405
uniprot id: A0A1A9EX55
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS17465
gene id: 1821621:A8C75_RS17465
uniprot id: A0A1A9F2T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1821621:A8C75 RS07015
gene id: 1821621:A8C75_RS07015
uniprot id: A0A1A9EWH6
names: Similarity
messages: Belongs to the transposase 8 family.

1821621:A8C75 RS10570
gene id: 1821621:A8C75_RS10570
uniprot id: A0A1A9EYZ8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1821621:A8C75 RS12205
gene id: 1821621:A8C75_RS12205
uniprot id: A0A1A9EZU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1821621:A8C75 RS21770
gene id: 1821621:A8C75_RS21770
uniprot id: A0A1A9F3F1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS12215
gene id: 1821621:A8C75_RS12215
uniprot id: A0A1A9EZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS00475
gene id: 1821621:A8C75_RS00475
uniprot id: A0A1A9ET87
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1821621:A8C75 RS01890
gene id: 1821621:A8C75_RS01890
uniprot id: A0A1A9ETV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1821621:A8C75 RS12870
gene id: 1821621:A8C75_RS12870
uniprot id: A0A1A9EYT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS12790
gene id: 1821621:A8C75_RS12790
uniprot id: A0A1A9F0F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1821621:A8C75 RS12125
gene id: 1821621:A8C75_RS12125
uniprot id: A0A1A9EYD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1821621:A8C75 RS16770
gene id: 1821621:A8C75_RS16770
uniprot id: A0A1A9F1C0
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1821621:A8C75 RS06230
gene id: 1821621:A8C75_RS06230
uniprot id: A0A1A9EWT4
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1821621:A8C75 RS11430
gene id: 1821621:A8C75_RS11430
uniprot id: A0A1A9F4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1821621:A8C75 RS00320
gene id: 1821621:A8C75_RS00320
uniprot id: A0A1A9ETR6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1821621:A8C75 RS17340
gene id: 1821621:A8C75_RS17340
uniprot id: A0A1A9F243
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1821621:A8C75 RS19310
gene id: 1821621:A8C75_RS19310
uniprot id: A0A1A9F2G0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1821621:A8C75 RS17165
gene id: 1821621:A8C75_RS17165
uniprot id: A0A1A9F2N0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1821621:A8C75 RS12795
gene id: 1821621:A8C75_RS12795
uniprot id: A0A1A9EZT8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS10490
gene id: 1821621:A8C75_RS10490
uniprot id: A0A1A9EYA6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS16635
gene id: 1821621:A8C75_RS16635
uniprot id: A0A1A9F194
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS07530
gene id: 1821621:A8C75_RS07530
uniprot id: A0A1A9EWV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1821621:A8C75 RS19755
gene id: 1821621:A8C75_RS19755
uniprot id: A0A1A9F2E3
names: Similarity
messages: Belongs to the TPP enzyme family.

1821621:A8C75 RS04185
gene id: 1821621:A8C75_RS04185
uniprot id: A0A1A9EW53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1821621:A8C75 RS08645
gene id: 1821621:A8C75_RS08645
uniprot id: A0A1A9EXG1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1821621:A8C75 RS13355
gene id: 1821621:A8C75_RS13355
uniprot id: A0A1A9F035
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1821621:A8C75 RS14340
gene id: 1821621:A8C75_RS14340
uniprot id: A0A1A9F1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1821621:A8C75 RS04670
gene id: 1821621:A8C75_RS04670
uniprot id: A0A1A9EWE1
names: Similarity
messages: Belongs to the TrpC family.

1821621:A8C75 RS01940
gene id: 1821621:A8C75_RS01940
uniprot id: A0A1A9ETY3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1821621:A8C75 RS10950
gene id: 1821621:A8C75_RS10950
uniprot id: A0A1A9EZJ0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1821621:A8C75 RS12610
gene id: 1821621:A8C75_RS12610
uniprot id: A0A1A9EZR2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS21250
gene id: 1821621:A8C75_RS21250
uniprot id: A0A1A9F4G9
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS21980
gene id: 1821621:A8C75_RS21980
uniprot id: A0A1A9F3X8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1821621:A8C75 RS16530
gene id: 1821621:A8C75_RS16530
uniprot id: A0A1A9F5R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1821621:A8C75 RS11235
gene id: 1821621:A8C75_RS11235
uniprot id: A0A1A9EZD6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS18780
gene id: 1821621:A8C75_RS18780
uniprot id: A0A1A9F268
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1821621:A8C75 RS19350
gene id: 1821621:A8C75_RS19350
uniprot id: A0A1A9F271
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1821621:A8C75 RS05650
gene id: 1821621:A8C75_RS05650
uniprot id: A0A1A9EWW7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1821621:A8C75 RS00570
gene id: 1821621:A8C75_RS00570
uniprot id: A0A1A9ESD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS04220
gene id: 1821621:A8C75_RS04220
uniprot id: A0A1A9EW33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1821621:A8C75 RS01105
gene id: 1821621:A8C75_RS01105
uniprot id: A0A1A9EU71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1821621:A8C75 RS05065
gene id: 1821621:A8C75_RS05065
uniprot id: A0A1A9EVP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS05155
gene id: 1821621:A8C75_RS05155
uniprot id: A0A1A9EWM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1821621:A8C75 RS06355
gene id: 1821621:A8C75_RS06355
uniprot id: A0A1A9EWM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1821621:A8C75 RS01850
gene id: 1821621:A8C75_RS01850
uniprot id: A0A1A9EUJ7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1821621:A8C75 RS07955
gene id: 1821621:A8C75_RS07955
uniprot id: A0A1A9EXN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1821621:A8C75 RS16835
gene id: 1821621:A8C75_RS16835
uniprot id: A0A1A9F513
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS05230
gene id: 1821621:A8C75_RS05230
uniprot id: A0A1A9EVL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1821621:A8C75 RS19100
gene id: 1821621:A8C75_RS19100
uniprot id: A0A1A9F3R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1821621:A8C75 RS21665
gene id: 1821621:A8C75_RS21665
uniprot id: A0A1A9F584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1821621:A8C75 RS01410
gene id: 1821621:A8C75_RS01410
uniprot id: A0A1A9EUK0
names: Similarity
messages: Belongs to the GSP E family.

1821621:A8C75 RS05810
gene id: 1821621:A8C75_RS05810
uniprot id: A0A1A9EVZ7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1821621:A8C75 RS22545
gene id: 1821621:A8C75_RS22545
uniprot id: A0A1A9F4H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1821621:A8C75 RS21265
gene id: 1821621:A8C75_RS21265
uniprot id: A0A1A9F363
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1821621:A8C75 RS21090
gene id: 1821621:A8C75_RS21090
uniprot id: A0A1A9F3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1821621:A8C75 RS10470
gene id: 1821621:A8C75_RS10470
uniprot id: A0A1A9EXI7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS05865
gene id: 1821621:A8C75_RS05865
uniprot id: A0A1A9EW07
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1821621:A8C75 RS06390
gene id: 1821621:A8C75_RS06390
uniprot id: A0A1A9EW66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1821621:A8C75 RS13050
gene id: 1821621:A8C75_RS13050
uniprot id: A0A1A9EZD8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1821621:A8C75 RS03500
gene id: 1821621:A8C75_RS03500
uniprot id: A0A1A9EVQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1821621:A8C75 RS17830
gene id: 1821621:A8C75_RS17830
uniprot id: A0A1A9F1P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS13990
gene id: 1821621:A8C75_RS13990
uniprot id: A0A1A9F0P6
names: Subcellular Location Annotation
messages: Cytoplasm

1821621:A8C75 RS10300
gene id: 1821621:A8C75_RS10300
uniprot id: A0A1A9EYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS02830
gene id: 1821621:A8C75_RS02830
uniprot id: A0A1A9EUV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1821621:A8C75 RS08725
gene id: 1821621:A8C75_RS08725
uniprot id: A0A1A9EY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS19665
gene id: 1821621:A8C75_RS19665
uniprot id: A0A1A9F3Y3
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS04810
gene id: 1821621:A8C75_RS04810
uniprot id: A0A1A9EVU4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1821621:A8C75 RS14885
gene id: 1821621:A8C75_RS14885
uniprot id: A0A1A9F0M4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1821621:A8C75 RS16645
gene id: 1821621:A8C75_RS16645
uniprot id: A0A1A9F1A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS04990
gene id: 1821621:A8C75_RS04990
uniprot id: A0A1A9F4G6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1821621:A8C75 RS19520
gene id: 1821621:A8C75_RS19520
uniprot id: A0A1A9F296
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS12185
gene id: 1821621:A8C75_RS12185
uniprot id: A0A1A9EZ28
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1821621:A8C75 RS19065
gene id: 1821621:A8C75_RS19065
uniprot id: A0A1A9F3A7
names: Similarity
messages: Belongs to the RutC family.

1821621:A8C75 RS08280
gene id: 1821621:A8C75_RS08280
uniprot id: A0A1A9EX43
names: Similarity
messages: Belongs to the asparagine synthetase family.

1821621:A8C75 RS01825
gene id: 1821621:A8C75_RS01825
uniprot id: A0A1A9ET35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS13150
gene id: 1821621:A8C75_RS13150
uniprot id: A0A1A9EZQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1821621:A8C75 RS13260
gene id: 1821621:A8C75_RS13260
uniprot id: A0A1A9EZS6
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS03460
gene id: 1821621:A8C75_RS03460
uniprot id: A0A1A9EUQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1821621:A8C75 RS13965
gene id: 1821621:A8C75_RS13965
uniprot id: A0A1A9EZT9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1821621:A8C75 RS11550
gene id: 1821621:A8C75_RS11550
uniprot id: A0A1A9EZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

1821621:A8C75 RS13720
gene id: 1821621:A8C75_RS13720
uniprot id: A0A1A9F0J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1821621:A8C75 RS14970
gene id: 1821621:A8C75_RS14970
uniprot id: A0A1A9F0I4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS07610
gene id: 1821621:A8C75_RS07610
uniprot id: A0A1A9EWS4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1821621:A8C75 RS19360
gene id: 1821621:A8C75_RS19360
uniprot id: A0A1A9F2H0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1821621:A8C75 RS04295
gene id: 1821621:A8C75_RS04295
uniprot id: A0A1A9EW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS05985
gene id: 1821621:A8C75_RS05985
uniprot id: A0A1A9EW62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS04050
gene id: 1821621:A8C75_RS04050
uniprot id: A0A1A9F4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1821621:A8C75 RS03820
gene id: 1821621:A8C75_RS03820
uniprot id: A0A1A9EUV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS03945
gene id: 1821621:A8C75_RS03945
uniprot id: A0A1A9EVC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS08155
gene id: 1821621:A8C75_RS08155
uniprot id: A0A1A9EXB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1821621:A8C75 RS22285
gene id: 1821621:A8C75_RS22285
uniprot id: A0A1A9F425
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1821621:A8C75 RS14490
gene id: 1821621:A8C75_RS14490
uniprot id: A0A1A9F0Z5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS22195
gene id: 1821621:A8C75_RS22195
uniprot id: A0A1A9F4L1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1821621:A8C75 RS21640
gene id: 1821621:A8C75_RS21640
uniprot id: A0A1A9F4P8
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1821621:A8C75 RS07760
gene id: 1821621:A8C75_RS07760
uniprot id: A0A1A9EW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1821621:A8C75 RS06120
gene id: 1821621:A8C75_RS06120
uniprot id: A0A1A9EX44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1821621:A8C75 RS21475
gene id: 1821621:A8C75_RS21475
uniprot id: A0A1A9F3A4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1821621:A8C75 RS09435
gene id: 1821621:A8C75_RS09435
uniprot id: A0A1A9EYX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1821621:A8C75 RS15555
gene id: 1821621:A8C75_RS15555
uniprot id: A0A1A9F1K2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1821621:A8C75 RS04585
gene id: 1821621:A8C75_RS04585
uniprot id: A0A1A9EVA4
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1821621:A8C75 RS08030
gene id: 1821621:A8C75_RS08030
uniprot id: A0A1A9EXH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1821621:A8C75 RS04040
gene id: 1821621:A8C75_RS04040
uniprot id: A0A1A9EV64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1821621:A8C75 RS09945
gene id: 1821621:A8C75_RS09945
uniprot id: A0A1A9EZ09
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1821621:A8C75 RS02810
gene id: 1821621:A8C75_RS02810
uniprot id: A0A1A9EUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS01910
gene id: 1821621:A8C75_RS01910
uniprot id: A0A1A9EUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1821621:A8C75 RS12675
gene id: 1821621:A8C75_RS12675
uniprot id: A0A1A9F0D8
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1821621:A8C75 RS12195
gene id: 1821621:A8C75_RS12195
uniprot id: A0A1A9F663
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1821621:A8C75 RS20575
gene id: 1821621:A8C75_RS20575
uniprot id: A0A1A9F3H6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS07105
gene id: 1821621:A8C75_RS07105
uniprot id: A0A1A9EWT9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1821621:A8C75 RS09545
gene id: 1821621:A8C75_RS09545
uniprot id: A0A1A9EY07
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS14925
gene id: 1821621:A8C75_RS14925
uniprot id: A0A1A9F1K5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS09410
gene id: 1821621:A8C75_RS09410
uniprot id: A0A1A9EYF0
names: Similarity
messages: Belongs to the UPF0047 family.

1821621:A8C75 RS07225
gene id: 1821621:A8C75_RS07225
uniprot id: A0A1A9EVW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS08860
gene id: 1821621:A8C75_RS08860
uniprot id: A0A1A9EY79
names: Similarity
messages: Belongs to the universal stress protein A family.

1821621:A8C75 RS03095
gene id: 1821621:A8C75_RS03095
uniprot id: A0A1A9EV03
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1821621:A8C75 RS17890
gene id: 1821621:A8C75_RS17890
uniprot id: A0A1A9F4V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1821621:A8C75 RS06980
gene id: 1821621:A8C75_RS06980
uniprot id: A0A1A9EWY8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1821621:A8C75 RS10075
gene id: 1821621:A8C75_RS10075
uniprot id: A0A1A9EZ81
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1821621:A8C75 RS04360
gene id: 1821621:A8C75_RS04360
uniprot id: A0A1A9EV52
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1821621:A8C75 RS02540
gene id: 1821621:A8C75_RS02540
uniprot id: A0A1A9EU77
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1821621:A8C75 RS13165
gene id: 1821621:A8C75_RS13165
uniprot id: A0A1A9EZI9
names: Similarity
messages: Belongs to the IMPACT family.

1821621:A8C75 RS07985
gene id: 1821621:A8C75_RS07985
uniprot id: A0A1A9EX88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1821621:A8C75 RS00645
gene id: 1821621:A8C75_RS00645
uniprot id: A0A1A9ETX5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1821621:A8C75 RS12160
gene id: 1821621:A8C75_RS12160
uniprot id: A0A1A9EZI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1821621:A8C75 RS21620
gene id: 1821621:A8C75_RS21620
uniprot id: A0A1A9F4K4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1821621:A8C75 RS17295
gene id: 1821621:A8C75_RS17295
uniprot id: A0A1A9F1S9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS02945
gene id: 1821621:A8C75_RS02945
uniprot id: A0A1A9EUS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1821621:A8C75 RS19085
gene id: 1821621:A8C75_RS19085
uniprot id: A0A1A9F6I0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1821621:A8C75 RS01005
gene id: 1821621:A8C75_RS01005
uniprot id: A0A1A9EUF6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1821621:A8C75 RS02900
gene id: 1821621:A8C75_RS02900
uniprot id: A0A1A9EVH8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS06150
gene id: 1821621:A8C75_RS06150
uniprot id: A0A1A9EX54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1821621:A8C75 RS14900
gene id: 1821621:A8C75_RS14900
uniprot id: A0A1A9F0F0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1821621:A8C75 RS18950
gene id: 1821621:A8C75_RS18950
uniprot id: A0A1A9F2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS18030
gene id: 1821621:A8C75_RS18030
uniprot id: A0A1A9F1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1821621:A8C75 RS20905
gene id: 1821621:A8C75_RS20905
uniprot id: A0A1A9F4K1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1821621:A8C75 RS16330
gene id: 1821621:A8C75_RS16330
uniprot id: A0A1A9F155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS13645
gene id: 1821621:A8C75_RS13645
uniprot id: A0A1A9EZU1
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1821621:A8C75 RS02620
gene id: 1821621:A8C75_RS02620
uniprot id: A0A1A9EV10
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS00750
gene id: 1821621:A8C75_RS00750
uniprot id: A0A1A9ETZ5
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1821621:A8C75 RS00020
gene id: 1821621:A8C75_RS00020
uniprot id: A0A1A9ETV1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1821621:A8C75 RS05950
gene id: 1821621:A8C75_RS05950
uniprot id: A0A1A9EWF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1821621:A8C75 RS17470
gene id: 1821621:A8C75_RS17470
uniprot id: A0A1A9F263
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1821621:A8C75 RS05705
gene id: 1821621:A8C75_RS05705
uniprot id: A0A1A9EV41
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1821621:A8C75 RS00390
gene id: 1821621:A8C75_RS00390
uniprot id: A0A1A9ETF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1821621:A8C75 RS10530
gene id: 1821621:A8C75_RS10530
uniprot id: A0A1A9EXJ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1821621:A8C75 RS02985
gene id: 1821621:A8C75_RS02985
uniprot id: A0A1A9EVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1821621:A8C75 RS04195
gene id: 1821621:A8C75_RS04195
uniprot id: A0A1A9EV25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1821621:A8C75 RS01495
gene id: 1821621:A8C75_RS01495
uniprot id: A0A1A9ESX4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS20585
gene id: 1821621:A8C75_RS20585
uniprot id: A0A1A9F2V2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1821621:A8C75 RS00595
gene id: 1821621:A8C75_RS00595
uniprot id: A0A1A9ETW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1821621:A8C75 RS09235
gene id: 1821621:A8C75_RS09235
uniprot id: A0A1A9EXK1
names: Similarity
messages: Belongs to the citrate synthase family.

1821621:A8C75 RS05575
gene id: 1821621:A8C75_RS05575
uniprot id: A0A1A9EWU4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS04680
gene id: 1821621:A8C75_RS04680
uniprot id: A0A1A9EVC7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1821621:A8C75 RS21590
gene id: 1821621:A8C75_RS21590
uniprot id: A0A1A9F405
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1821621:A8C75 RS09055
gene id: 1821621:A8C75_RS09055
uniprot id: A0A1A9EXK4
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1821621:A8C75 RS21050
gene id: 1821621:A8C75_RS21050
uniprot id: A0A1A9F325
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1821621:A8C75 RS08525
gene id: 1821621:A8C75_RS08525
uniprot id: A0A1A9EYD8
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS15370
gene id: 1821621:A8C75_RS15370
uniprot id: A0A1A9F0V7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1821621:A8C75 RS17010
gene id: 1821621:A8C75_RS17010
uniprot id: A0A1A9F2B3
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS00585
gene id: 1821621:A8C75_RS00585
uniprot id: A0A1A9ETA7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1821621:A8C75 RS09970
gene id: 1821621:A8C75_RS09970
uniprot id: A0A1A9EXA1
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1821621:A8C75 RS13475
gene id: 1821621:A8C75_RS13475
uniprot id: A0A1A9EZR0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS11605
gene id: 1821621:A8C75_RS11605
uniprot id: A0A1A9EYZ3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1821621:A8C75 RS19120
gene id: 1821621:A8C75_RS19120
uniprot id: A0A1A9F218
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1821621:A8C75 RS06260
gene id: 1821621:A8C75_RS06260
uniprot id: A0A1A9EVD3
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1821621:A8C75 RS12750
gene id: 1821621:A8C75_RS12750
uniprot id: A0A1A9EZI4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1821621:A8C75 RS11135
gene id: 1821621:A8C75_RS11135
uniprot id: A0A1A9EYR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS05540
gene id: 1821621:A8C75_RS05540
uniprot id: A0A1A9EW13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1821621:A8C75 RS04125
gene id: 1821621:A8C75_RS04125
uniprot id: A0A1A9EVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS17770
gene id: 1821621:A8C75_RS17770
uniprot id: A0A1A9F1V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS17200
gene id: 1821621:A8C75_RS17200
uniprot id: A0A1A9F1J7
names: Similarity
messages: Belongs to the GARS family.

1821621:A8C75 RS15725
gene id: 1821621:A8C75_RS15725
uniprot id: A0A1A9F1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1821621:A8C75 RS14320
gene id: 1821621:A8C75_RS14320
uniprot id: A0A1A9F193
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1821621:A8C75 RS17075
gene id: 1821621:A8C75_RS17075
uniprot id: A0A1A9F2Q5
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS20520
gene id: 1821621:A8C75_RS20520
uniprot id: A0A1A9F3G6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1821621:A8C75 RS05215
gene id: 1821621:A8C75_RS05215
uniprot id: A0A1A9EUV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1821621:A8C75 RS02070
gene id: 1821621:A8C75_RS02070
uniprot id: A0A1A9EUX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1821621:A8C75 RS14210
gene id: 1821621:A8C75_RS14210
uniprot id: A0A1A9F171
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS21505
gene id: 1821621:A8C75_RS21505
uniprot id: A0A1A9F495
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1821621:A8C75 RS00490
gene id: 1821621:A8C75_RS00490
uniprot id: A0A1A9ETL7
names: Similarity
messages: Belongs to the IlvD/Edd family.

1821621:A8C75 RS13230
gene id: 1821621:A8C75_RS13230
uniprot id: A0A1A9EZG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS21565
gene id: 1821621:A8C75_RS21565
uniprot id: A0A1A9F3M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS11865
gene id: 1821621:A8C75_RS11865
uniprot id: A0A1A9EYY4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS19035
gene id: 1821621:A8C75_RS19035
uniprot id: A0A1A9F2N8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS08035
gene id: 1821621:A8C75_RS08035
uniprot id: A0A1A9EXT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1821621:A8C75 RS03605
gene id: 1821621:A8C75_RS03605
uniprot id: A0A1A9EUR4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1821621:A8C75 RS21660
gene id: 1821621:A8C75_RS21660
uniprot id: A0A1A9F3D3
names: Subcellular Location Annotation
messages: Cytoplasm

1821621:A8C75 RS21410
gene id: 1821621:A8C75_RS21410
uniprot id: A0A1A9F3X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1821621:A8C75 RS14065
gene id: 1821621:A8C75_RS14065
uniprot id: A0A1A9F168
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS05795
gene id: 1821621:A8C75_RS05795
uniprot id: A0A1A9EW63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1821621:A8C75 RS21225
gene id: 1821621:A8C75_RS21225
uniprot id: A0A1A9F4D1
names: Similarity
messages: Belongs to the TPP enzyme family.

1821621:A8C75 RS17350
gene id: 1821621:A8C75_RS17350
uniprot id: A0A1A9F1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1821621:A8C75 RS17765
gene id: 1821621:A8C75_RS17765
uniprot id: A0A1A9F1B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS06615
gene id: 1821621:A8C75_RS06615
uniprot id: A0A1A9EX06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS21880
gene id: 1821621:A8C75_RS21880
uniprot id: A0A1A9F3W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1821621:A8C75 RS09265
gene id: 1821621:A8C75_RS09265
uniprot id: A0A1A9EYE2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS15115
gene id: 1821621:A8C75_RS15115
uniprot id: A0A1A9F0E9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1821621:A8C75 RS18915
gene id: 1821621:A8C75_RS18915
uniprot id: A0A1A9F2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS12255
gene id: 1821621:A8C75_RS12255
uniprot id: A0A1A9EZ52
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1821621:A8C75 RS05300
gene id: 1821621:A8C75_RS05300
uniprot id: A0A1A9EWB4
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1821621:A8C75 RS20870
gene id: 1821621:A8C75_RS20870
uniprot id: A0A1A9F382
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS12715
gene id: 1821621:A8C75_RS12715
uniprot id: A0A1A9EZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS22000
gene id: 1821621:A8C75_RS22000
uniprot id: A0A1A9F4S1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1821621:A8C75 RS18740
gene id: 1821621:A8C75_RS18740
uniprot id: A0A1A9F3G4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1821621:A8C75 RS22040
gene id: 1821621:A8C75_RS22040
uniprot id: A0A1A9F3Y9
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS11610
gene id: 1821621:A8C75_RS11610
uniprot id: A0A1A9EZX5
names: Similarity
messages: Belongs to the peptidase S24 family.

1821621:A8C75 RS02845
gene id: 1821621:A8C75_RS02845
uniprot id: A0A1A9EVG2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1821621:A8C75 RS06135
gene id: 1821621:A8C75_RS06135
uniprot id: A0A1A9EWB8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1821621:A8C75 RS14220
gene id: 1821621:A8C75_RS14220
uniprot id: A0A1A9F0U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1821621:A8C75 RS00090
gene id: 1821621:A8C75_RS00090
uniprot id: A0A1A9ETM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS01620
gene id: 1821621:A8C75_RS01620
uniprot id: A0A1A9ETV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1821621:A8C75 RS16790
gene id: 1821621:A8C75_RS16790
uniprot id: A0A1A9F265
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1821621:A8C75 RS22390
gene id: 1821621:A8C75_RS22390
uniprot id: A0A1A9F5E6
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1821621:A8C75 RS11140
gene id: 1821621:A8C75_RS11140
uniprot id: A0A1A9EZR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS16660
gene id: 1821621:A8C75_RS16660
uniprot id: A0A1A9F2F1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS00565
gene id: 1821621:A8C75_RS00565
uniprot id: A0A1A9EU69
names: Similarity
messages: Belongs to the P(II) protein family.

1821621:A8C75 RS01385
gene id: 1821621:A8C75_RS01385
uniprot id: A0A1A9ESV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1821621:A8C75 RS18770
gene id: 1821621:A8C75_RS18770
uniprot id: A0A1A9F4W4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS03365
gene id: 1821621:A8C75_RS03365
uniprot id: A0A1A9EUT6
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS06605
gene id: 1821621:A8C75_RS06605
uniprot id: A0A1A9EWA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1821621:A8C75 RS17920
gene id: 1821621:A8C75_RS17920
uniprot id: A0A1A9F235
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1821621:A8C75 RS02300
gene id: 1821621:A8C75_RS02300
uniprot id: A0A1A9EV46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS10330
gene id: 1821621:A8C75_RS10330
uniprot id: A0A1A9EYX2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1821621:A8C75 RS05715
gene id: 1821621:A8C75_RS05715
uniprot id: A0A1A9EVU7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1821621:A8C75 RS12825
gene id: 1821621:A8C75_RS12825
uniprot id: A0A1A9F4K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1821621:A8C75 RS10795
gene id: 1821621:A8C75_RS10795
uniprot id: A0A1A9EXQ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS17430
gene id: 1821621:A8C75_RS17430
uniprot id: A0A1A9F1U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1821621:A8C75 RS04595
gene id: 1821621:A8C75_RS04595
uniprot id: A0A1A9EVY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS22315
gene id: 1821621:A8C75_RS22315
uniprot id: A0A1A9F514
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1821621:A8C75 RS07745
gene id: 1821621:A8C75_RS07745
uniprot id: A0A1A9EXN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS01520
gene id: 1821621:A8C75_RS01520
uniprot id: A0A1A9EUM2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS01110
gene id: 1821621:A8C75_RS01110
uniprot id: A0A1A9ETT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1821621:A8C75 RS17320
gene id: 1821621:A8C75_RS17320
uniprot id: A0A1A9F1L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1821621:A8C75 RS22215
gene id: 1821621:A8C75_RS22215
uniprot id: A0A1A9F3M5
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1821621:A8C75 RS03610
gene id: 1821621:A8C75_RS03610
uniprot id: A0A1A9EUX4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1821621:A8C75 RS00870
gene id: 1821621:A8C75_RS00870
uniprot id: A0A1A9ETG2
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

1821621:A8C75 RS13110
gene id: 1821621:A8C75_RS13110
uniprot id: A0A1A9EZH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1821621:A8C75 RS17375
gene id: 1821621:A8C75_RS17375
uniprot id: A0A1A9F1H2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1821621:A8C75 RS21135
gene id: 1821621:A8C75_RS21135
uniprot id: A0A1A9F4F5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1821621:A8C75 RS04865
gene id: 1821621:A8C75_RS04865
uniprot id: A0A1A9EW67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS20335
gene id: 1821621:A8C75_RS20335
uniprot id: A0A1A9F317
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1821621:A8C75 RS04250
gene id: 1821621:A8C75_RS04250
uniprot id: A0A1A9EV36
names: Similarity
messages: Belongs to the MotB family.

1821621:A8C75 RS07830
gene id: 1821621:A8C75_RS07830
uniprot id: A0A1A9EWW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1821621:A8C75 RS12740
gene id: 1821621:A8C75_RS12740
uniprot id: A0A1A9EZS8
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS18890
gene id: 1821621:A8C75_RS18890
uniprot id: A0A1A9F290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS21210
gene id: 1821621:A8C75_RS21210
uniprot id: A0A1A9F3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1821621:A8C75 RS20985
gene id: 1821621:A8C75_RS20985
uniprot id: A0A1A9F316
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1821621:A8C75 RS04870
gene id: 1821621:A8C75_RS04870
uniprot id: A0A1A9EVQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS07980
gene id: 1821621:A8C75_RS07980
uniprot id: A0A1A9EXS3
names: Similarity
messages: Belongs to the YkuD family.

1821621:A8C75 RS22615
gene id: 1821621:A8C75_RS22615
uniprot id: A0A1A9F3U0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1821621:A8C75 RS08840
gene id: 1821621:A8C75_RS08840
uniprot id: A0A1A9EXI5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS18410
gene id: 1821621:A8C75_RS18410
uniprot id: A0A1A9F309
names: Similarity
messages: Belongs to the ArsC family.

1821621:A8C75 RS13700
gene id: 1821621:A8C75_RS13700
uniprot id: A0A1A9F0L7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1821621:A8C75 RS06285
gene id: 1821621:A8C75_RS06285
uniprot id: A0A1A9EX79
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS16695
gene id: 1821621:A8C75_RS16695
uniprot id: A0A1A9F2H9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1821621:A8C75 RS21085
gene id: 1821621:A8C75_RS21085
uniprot id: A0A1A9F4E6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1821621:A8C75 RS08180
gene id: 1821621:A8C75_RS08180
uniprot id: A0A1A9EX86
names: Similarity
messages: Belongs to the UPF0260 family.

1821621:A8C75 RS00075
gene id: 1821621:A8C75_RS00075
uniprot id: A0A1A9ESX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1821621:A8C75 RS01330
gene id: 1821621:A8C75_RS01330
uniprot id: A0A1A9EUL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1821621:A8C75 RS12250
gene id: 1821621:A8C75_RS12250
uniprot id: A0A1A9EYZ2
names: Subunit
messages: Homodimer.

1821621:A8C75 RS03665
gene id: 1821621:A8C75_RS03665
uniprot id: A0A1A9EUS2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1821621:A8C75 RS02255
gene id: 1821621:A8C75_RS02255
uniprot id: A0A1A9EU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS13335
gene id: 1821621:A8C75_RS13335
uniprot id: A0A1A9EZI7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1821621:A8C75 RS00005
gene id: 1821621:A8C75_RS00005
uniprot id: A0A1A9ESW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1821621:A8C75 RS13390
gene id: 1821621:A8C75_RS13390
uniprot id: A0A1A9F4X1
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1821621:A8C75 RS02125
gene id: 1821621:A8C75_RS02125
uniprot id: A0A1A9EUZ3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1821621:A8C75 RS13590
gene id: 1821621:A8C75_RS13590
uniprot id: A0A1A9EZS9
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1821621:A8C75 RS09645
gene id: 1821621:A8C75_RS09645
uniprot id: A0A1A9EYW0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS00670
gene id: 1821621:A8C75_RS00670
uniprot id: A0A1A9ETK6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS07155
gene id: 1821621:A8C75_RS07155
uniprot id: A0A1A9EXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS01700
gene id: 1821621:A8C75_RS01700
uniprot id: A0A1A9EU43
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS08295
gene id: 1821621:A8C75_RS08295
uniprot id: A0A1A9EXV2
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS15755
gene id: 1821621:A8C75_RS15755
uniprot id: A0A1A9F227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS13235
gene id: 1821621:A8C75_RS13235
uniprot id: A0A1A9EZL9
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS13145
gene id: 1821621:A8C75_RS13145
uniprot id: A0A1A9F095
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS02990
gene id: 1821621:A8C75_RS02990
uniprot id: A0A1A9EUY0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1821621:A8C75 RS12420
gene id: 1821621:A8C75_RS12420
uniprot id: A0A1A9EZ90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS21105
gene id: 1821621:A8C75_RS21105
uniprot id: A0A1A9F3H0
names: Similarity
messages: Belongs to the MoaD family.

1821621:A8C75 RS20500
gene id: 1821621:A8C75_RS20500
uniprot id: A0A1A9F406
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS20560
gene id: 1821621:A8C75_RS20560
uniprot id: A0A1A9F4E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1821621:A8C75 RS12175
gene id: 1821621:A8C75_RS12175
uniprot id: A0A1A9F076
names: Subcellular Location Annotation
messages: Cytoplasm

1821621:A8C75 RS12410
gene id: 1821621:A8C75_RS12410
uniprot id: A0A1A9EZ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS00765
gene id: 1821621:A8C75_RS00765
uniprot id: A0A1A9ETR7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS21840
gene id: 1821621:A8C75_RS21840
uniprot id: A0A1A9F4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1821621:A8C75 RS05275
gene id: 1821621:A8C75_RS05275
uniprot id: A0A1A9EUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1821621:A8C75 RS11000
gene id: 1821621:A8C75_RS11000
uniprot id: A0A1A9EYE8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS06975
gene id: 1821621:A8C75_RS06975
uniprot id: A0A1A9F4J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1821621:A8C75 RS19535
gene id: 1821621:A8C75_RS19535
uniprot id: A0A1A9F2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1821621:A8C75 RS07790
gene id: 1821621:A8C75_RS07790
uniprot id: A0A1A9EXY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1821621:A8C75 RS00660
gene id: 1821621:A8C75_RS00660
uniprot id: A0A1A9ETZ7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS02085
gene id: 1821621:A8C75_RS02085
uniprot id: A0A1A9EUB3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1821621:A8C75 RS19320
gene id: 1821621:A8C75_RS19320
uniprot id: A0A1A9F3E6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1821621:A8C75 RS15440
gene id: 1821621:A8C75_RS15440
uniprot id: A0A1A9F0P9
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS00080
gene id: 1821621:A8C75_RS00080
uniprot id: A0A1A9ESX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1821621:A8C75 RS17315
gene id: 1821621:A8C75_RS17315
uniprot id: A0A1A9F1G2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1821621:A8C75 RS09350
gene id: 1821621:A8C75_RS09350
uniprot id: A0A1A9EXM1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1821621:A8C75 RS00110
gene id: 1821621:A8C75_RS00110
uniprot id: A0A1A9ETA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1821621:A8C75 RS22590
gene id: 1821621:A8C75_RS22590
uniprot id: A0A1A9F5F1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1821621:A8C75 RS13735
gene id: 1821621:A8C75_RS13735
uniprot id: A0A1A9EZA0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS03645
gene id: 1821621:A8C75_RS03645
uniprot id: A0A1A9EVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS10605
gene id: 1821621:A8C75_RS10605
uniprot id: A0A1A9EZ21
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS21260
gene id: 1821621:A8C75_RS21260
uniprot id: A0A1A9F4W0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1821621:A8C75 RS21470
gene id: 1821621:A8C75_RS21470
uniprot id: A0A1A9F4Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1821621:A8C75 RS02380
gene id: 1821621:A8C75_RS02380
uniprot id: A0A1A9EU95
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1821621:A8C75 RS19495
gene id: 1821621:A8C75_RS19495
uniprot id: A0A1A9F3V4
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1821621:A8C75 RS00720
gene id: 1821621:A8C75_RS00720
uniprot id: A0A1A9ETL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1821621:A8C75 RS17635
gene id: 1821621:A8C75_RS17635
uniprot id: A0A1A9F2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1821621:A8C75 RS16155
gene id: 1821621:A8C75_RS16155
uniprot id: A0A1A9F109
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1821621:A8C75 RS12415
gene id: 1821621:A8C75_RS12415
uniprot id: A0A1A9EZ24
names: Similarity
messages: Belongs to the pyruvate kinase family.

1821621:A8C75 RS11815
gene id: 1821621:A8C75_RS11815
uniprot id: A0A1A9EZM6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1821621:A8C75 RS13195
gene id: 1821621:A8C75_RS13195
uniprot id: A0A1A9F0A8
names: Similarity
messages: Belongs to the acylphosphatase family.

1821621:A8C75 RS20315
gene id: 1821621:A8C75_RS20315
uniprot id: A0A1A9F563
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1821621:A8C75 RS06855
gene id: 1821621:A8C75_RS06855
uniprot id: A0A1A9EWK7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS05260
gene id: 1821621:A8C75_RS05260
uniprot id: A0A1A9EWE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1821621:A8C75 RS09295
gene id: 1821621:A8C75_RS09295
uniprot id: A0A1A9EXQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1821621:A8C75 RS16190
gene id: 1821621:A8C75_RS16190
uniprot id: A0A1A9F192
names: Similarity
messages: Belongs to the glutamine synthetase family.

1821621:A8C75 RS20720
gene id: 1821621:A8C75_RS20720
uniprot id: A0A1A9F4H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1821621:A8C75 RS13865
gene id: 1821621:A8C75_RS13865
uniprot id: A0A1A9F0P7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS05915
gene id: 1821621:A8C75_RS05915
uniprot id: A0A1A9EX11
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1821621:A8C75 RS20945
gene id: 1821621:A8C75_RS20945
uniprot id: A0A1A9F3B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1821621:A8C75 RS03125
gene id: 1821621:A8C75_RS03125
uniprot id: A0A1A9EUJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS05475
gene id: 1821621:A8C75_RS05475
uniprot id: A0A1A9EWS2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1821621:A8C75 RS11265
gene id: 1821621:A8C75_RS11265
uniprot id: A0A1A9EZB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS22720
gene id: 1821621:A8C75_RS22720
uniprot id: A0A1A9F5K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1821621:A8C75 RS16420
gene id: 1821621:A8C75_RS16420
uniprot id: A0A1A9F0N0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS08625
gene id: 1821621:A8C75_RS08625
uniprot id: A0A1A9F4M6
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS01070
gene id: 1821621:A8C75_RS01070
uniprot id: A0A1A9ETH5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1821621:A8C75 RS00215
gene id: 1821621:A8C75_RS00215
uniprot id: A0A1A9ETC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS02955
gene id: 1821621:A8C75_RS02955
uniprot id: A0A1A9ETS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1821621:A8C75 RS18460
gene id: 1821621:A8C75_RS18460
uniprot id: A0A1A9F321
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1821621:A8C75 RS02475
gene id: 1821621:A8C75_RS02475
uniprot id: A0A1A9EU66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1821621:A8C75 RS05325
gene id: 1821621:A8C75_RS05325
uniprot id: A0A1A9EWQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1821621:A8C75 RS06160
gene id: 1821621:A8C75_RS06160
uniprot id: A0A1A9EW59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS12580
gene id: 1821621:A8C75_RS12580
uniprot id: A0A1A9EZ94
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS16640
gene id: 1821621:A8C75_RS16640
uniprot id: A0A1A9F148
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS00120
gene id: 1821621:A8C75_RS00120
uniprot id: A0A1A9ES54
names: Similarity
messages: Belongs to the DprA/Smf family.

1821621:A8C75 RS00140
gene id: 1821621:A8C75_RS00140
uniprot id: A0A1A9ETN8
names: Similarity
messages: Belongs to the peptidase S16 family.

1821621:A8C75 RS16810
gene id: 1821621:A8C75_RS16810
uniprot id: A0A1A9F1C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1821621:A8C75 RS00210
gene id: 1821621:A8C75_RS00210
uniprot id: A0A1A9ETR0
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS00900
gene id: 1821621:A8C75_RS00900
uniprot id: A0A1A9ETP5
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1821621:A8C75 RS21045
gene id: 1821621:A8C75_RS21045
uniprot id: A0A1A9F4S0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1821621:A8C75 RS12920
gene id: 1821621:A8C75_RS12920
uniprot id: A0A1A9F0K7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1821621:A8C75 RS16010
gene id: 1821621:A8C75_RS16010
uniprot id: A0A1A9F241
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1821621:A8C75 RS21455
gene id: 1821621:A8C75_RS21455
uniprot id: A0A1A9F485
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1821621:A8C75 RS12940
gene id: 1821621:A8C75_RS12940
uniprot id: A0A1A9EZH5
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS05355
gene id: 1821621:A8C75_RS05355
uniprot id: A0A1A9EWC4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1821621:A8C75 RS02895
gene id: 1821621:A8C75_RS02895
uniprot id: A0A1A9EUR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS20735
gene id: 1821621:A8C75_RS20735
uniprot id: A0A1A9F3K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS00250
gene id: 1821621:A8C75_RS00250
uniprot id: A0A1A9ET48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1821621:A8C75 RS21730
gene id: 1821621:A8C75_RS21730
uniprot id: A0A1A9F3N4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1821621:A8C75 RS17050
gene id: 1821621:A8C75_RS17050
uniprot id: A0A1A9F2A3
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1821621:A8C75 RS19180
gene id: 1821621:A8C75_RS19180
uniprot id: A0A1A9F2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1821621:A8C75 RS05760
gene id: 1821621:A8C75_RS05760
uniprot id: A0A1A9EVY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1821621:A8C75 RS21315
gene id: 1821621:A8C75_RS21315
uniprot id: A0A1A9F4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1821621:A8C75 RS07270
gene id: 1821621:A8C75_RS07270
uniprot id: A0A1A9EWW9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS20065
gene id: 1821621:A8C75_RS20065
uniprot id: A0A1A9F3T5
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS02600
gene id: 1821621:A8C75_RS02600
uniprot id: A0A1A9EUZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1821621:A8C75 RS22560
gene id: 1821621:A8C75_RS22560
uniprot id: A0A1A9F476
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1821621:A8C75 RS05535
gene id: 1821621:A8C75_RS05535
uniprot id: A0A1A9EWI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1821621:A8C75 RS18070
gene id: 1821621:A8C75_RS18070
uniprot id: A0A1A9F2H1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS19765
gene id: 1821621:A8C75_RS19765
uniprot id: A0A1A9F2N9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS19670
gene id: 1821621:A8C75_RS19670
uniprot id: A0A1A9F3C7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS24040
gene id: 1821621:A8C75_RS24040
uniprot id: A0A1A9F3T7
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1821621:A8C75 RS12495
gene id: 1821621:A8C75_RS12495
uniprot id: A0A1A9EZY0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1821621:A8C75 RS18830
gene id: 1821621:A8C75_RS18830
uniprot id: A0A1A9F2D7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS11940
gene id: 1821621:A8C75_RS11940
uniprot id: A0A1A9EZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1821621:A8C75 RS22780
gene id: 1821621:A8C75_RS22780
uniprot id: A0A1A9F3X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1821621:A8C75 RS22080
gene id: 1821621:A8C75_RS22080
uniprot id: A0A1A9F565
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1821621:A8C75 RS19890
gene id: 1821621:A8C75_RS19890
uniprot id: A0A1A9F2G3
names: Similarity
messages: Belongs to the Dps family.

1821621:A8C75 RS21450
gene id: 1821621:A8C75_RS21450
uniprot id: A0A1A9F507
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1821621:A8C75 RS12965
gene id: 1821621:A8C75_RS12965
uniprot id: A0A1A9F064
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1821621:A8C75 RS05185
gene id: 1821621:A8C75_RS05185
uniprot id: A0A1A9F5D3
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1821621:A8C75 RS07450
gene id: 1821621:A8C75_RS07450
uniprot id: A0A1A9EXT1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1821621:A8C75 RS22510
gene id: 1821621:A8C75_RS22510
uniprot id: A0A1A9F427
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS00015
gene id: 1821621:A8C75_RS00015
uniprot id: A0A1A9ETL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1821621:A8C75 RS20505
gene id: 1821621:A8C75_RS20505
uniprot id: A0A1A9F4D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS15860
gene id: 1821621:A8C75_RS15860
uniprot id: A0A1A9F237
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1821621:A8C75 RS12190
gene id: 1821621:A8C75_RS12190
uniprot id: A0A1A9EYY0
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1821621:A8C75 RS21110
gene id: 1821621:A8C75_RS21110
uniprot id: A0A1A9F3C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1821621:A8C75 RS03795
gene id: 1821621:A8C75_RS03795
uniprot id: A0A1A9EV95
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS05735
gene id: 1821621:A8C75_RS05735
uniprot id: A0A1A9EWB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1821621:A8C75 RS13010
gene id: 1821621:A8C75_RS13010
uniprot id: A0A1A9EZX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1821621:A8C75 RS15820
gene id: 1821621:A8C75_RS15820
uniprot id: A0A1A9F0V2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1821621:A8C75 RS17520
gene id: 1821621:A8C75_RS17520
uniprot id: A0A1A9F273
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS04085
gene id: 1821621:A8C75_RS04085
uniprot id: A0A1A9EUB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1821621:A8C75 RS02950
gene id: 1821621:A8C75_RS02950
uniprot id: A0A1A9EVJ1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1821621:A8C75 RS21740
gene id: 1821621:A8C75_RS21740
uniprot id: A0A1A9F4M7
names: Similarity
messages: Belongs to the HSP15 family.

1821621:A8C75 RS10355
gene id: 1821621:A8C75_RS10355
uniprot id: A0A1A9EZC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1821621:A8C75 RS17905
gene id: 1821621:A8C75_RS17905
uniprot id: A0A1A9F308
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1821621:A8C75 RS02685
gene id: 1821621:A8C75_RS02685
uniprot id: A0A1A9EUM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1821621:A8C75 RS06125
gene id: 1821621:A8C75_RS06125
uniprot id: A0A1A9EWI8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1821621:A8C75 RS08200
gene id: 1821621:A8C75_RS08200
uniprot id: A0A1A9EXW8
names: Similarity
messages: Belongs to the peptidase S41A family.

1821621:A8C75 RS10850
gene id: 1821621:A8C75_RS10850
uniprot id: A0A1A9EZL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS13650
gene id: 1821621:A8C75_RS13650
uniprot id: A0A1A9F0K8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS06840
gene id: 1821621:A8C75_RS06840
uniprot id: A0A1A9EVP2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1821621:A8C75 RS09490
gene id: 1821621:A8C75_RS09490
uniprot id: A0A1A9EXZ4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1821621:A8C75 RS02430
gene id: 1821621:A8C75_RS02430
uniprot id: A0A1A9EUA5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS07235
gene id: 1821621:A8C75_RS07235
uniprot id: A0A1A9EWL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1821621:A8C75 RS05320
gene id: 1821621:A8C75_RS05320
uniprot id: A0A1A9EVX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1821621:A8C75 RS08755
gene id: 1821621:A8C75_RS08755
uniprot id: A0A1A9EXF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS18145
gene id: 1821621:A8C75_RS18145
uniprot id: A0A1A9F549
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1821621:A8C75 RS19405
gene id: 1821621:A8C75_RS19405
uniprot id: A0A1A9F577
names: Similarity
messages: Belongs to the cytochrome P450 family.

1821621:A8C75 RS18325
gene id: 1821621:A8C75_RS18325
uniprot id: A0A1A9F248
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS08020
gene id: 1821621:A8C75_RS08020
uniprot id: A0A1A9EXP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1821621:A8C75 RS12030
gene id: 1821621:A8C75_RS12030
uniprot id: A0A1A9EZ10
names: Similarity
messages: Belongs to the YoeB family.

1821621:A8C75 RS12490
gene id: 1821621:A8C75_RS12490
uniprot id: A0A1A9EZP1
names: Similarity
messages: Belongs to the thioredoxin family.

1821621:A8C75 RS22730
gene id: 1821621:A8C75_RS22730
uniprot id: A0A1A9F4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1821621:A8C75 RS02175
gene id: 1821621:A8C75_RS02175
uniprot id: A0A1A9EV02
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS06335
gene id: 1821621:A8C75_RS06335
uniprot id: A0A1A9EWB7
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1821621:A8C75 RS20345
gene id: 1821621:A8C75_RS20345
uniprot id: A0A1A9F4A2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1821621:A8C75 RS09290
gene id: 1821621:A8C75_RS09290
uniprot id: A0A1A9EXK9
names: Similarity
messages: Belongs to the UPF0178 family.

1821621:A8C75 RS02890
gene id: 1821621:A8C75_RS02890
uniprot id: A0A1A9EV62
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1821621:A8C75 RS12020
gene id: 1821621:A8C75_RS12020
uniprot id: A0A1A9EZ05
names: Similarity
messages: Belongs to the group II decarboxylase family.

1821621:A8C75 RS00695
gene id: 1821621:A8C75_RS00695
uniprot id: A0A1A9ETC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS02115
gene id: 1821621:A8C75_RS02115
uniprot id: A0A1A9F408
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1821621:A8C75 RS06540
gene id: 1821621:A8C75_RS06540
uniprot id: A0A1A9EVI7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS04935
gene id: 1821621:A8C75_RS04935
uniprot id: A0A1A9EVQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1821621:A8C75 RS06460
gene id: 1821621:A8C75_RS06460
uniprot id: A0A1A9EWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1821621:A8C75 RS02000
gene id: 1821621:A8C75_RS02000
uniprot id: A0A1A9ETZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS02730
gene id: 1821621:A8C75_RS02730
uniprot id: A0A1A9EUS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1821621:A8C75 RS18100
gene id: 1821621:A8C75_RS18100
uniprot id: A0A1A9F1U4
names: Similarity
messages: Belongs to the DinB family.

1821621:A8C75 RS19605
gene id: 1821621:A8C75_RS19605
uniprot id: A0A1A9F3X3
names: Similarity
messages: Belongs to the GST superfamily.

1821621:A8C75 RS17280
gene id: 1821621:A8C75_RS17280
uniprot id: A0A1A9F2Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1821621:A8C75 RS01130
gene id: 1821621:A8C75_RS01130
uniprot id: A0A1A9ETG5
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1821621:A8C75 RS17825
gene id: 1821621:A8C75_RS17825
uniprot id: A0A1A9F1V9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS15960
gene id: 1821621:A8C75_RS15960
uniprot id: A0A1A9F6D4
names: Similarity
messages: Belongs to the PspA/IM30 family.

1821621:A8C75 RS15400
gene id: 1821621:A8C75_RS15400
uniprot id: A0A1A9F1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS12680
gene id: 1821621:A8C75_RS12680
uniprot id: A0A1A9EZR8
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1821621:A8C75 RS07725
gene id: 1821621:A8C75_RS07725
uniprot id: A0A1A9EX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1821621:A8C75 RS18415
gene id: 1821621:A8C75_RS18415
uniprot id: A0A1A9F2C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS20900
gene id: 1821621:A8C75_RS20900
uniprot id: A0A1A9F472
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS20230
gene id: 1821621:A8C75_RS20230
uniprot id: A0A1A9F3W2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS21195
gene id: 1821621:A8C75_RS21195
uniprot id: A0A1A9F3T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

1821621:A8C75 RS09120
gene id: 1821621:A8C75_RS09120
uniprot id: A0A1A9EXM7
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1821621:A8C75 RS18880
gene id: 1821621:A8C75_RS18880
uniprot id: A0A1A9F1X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1821621:A8C75 RS21690
gene id: 1821621:A8C75_RS21690
uniprot id: A0A1A9F4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1821621:A8C75 RS01585
gene id: 1821621:A8C75_RS01585
uniprot id: A0A1A9EUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1821621:A8C75 RS17420
gene id: 1821621:A8C75_RS17420
uniprot id: A0A1A9F253
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1821621:A8C75 RS12860
gene id: 1821621:A8C75_RS12860
uniprot id: A0A1A9EZK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1821621:A8C75 RS05945
gene id: 1821621:A8C75_RS05945
uniprot id: A0A1A9EX12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1821621:A8C75 RS14030
gene id: 1821621:A8C75_RS14030
uniprot id: A0A1A9F0T3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1821621:A8C75 RS20305
gene id: 1821621:A8C75_RS20305
uniprot id: A0A1A9F4E7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1821621:A8C75 RS03875
gene id: 1821621:A8C75_RS03875
uniprot id: A0A1A9EUW0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS11880
gene id: 1821621:A8C75_RS11880
uniprot id: A0A1A9EZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS00505
gene id: 1821621:A8C75_RS00505
uniprot id: A0A1A9ETH8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1821621:A8C75 RS22235
gene id: 1821621:A8C75_RS22235
uniprot id: A0A1A9F4W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1821621:A8C75 RS05030
gene id: 1821621:A8C75_RS05030
uniprot id: A0A1A9EVY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1821621:A8C75 RS20170
gene id: 1821621:A8C75_RS20170
uniprot id: A0A1A9F4Y6
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1821621:A8C75 RS04175
gene id: 1821621:A8C75_RS04175
uniprot id: A0A1A9EVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS09515
gene id: 1821621:A8C75_RS09515
uniprot id: A0A1A9EXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1821621:A8C75 RS22540
gene id: 1821621:A8C75_RS22540
uniprot id: A0A1A9F553
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1821621:A8C75 RS07800
gene id: 1821621:A8C75_RS07800
uniprot id: A0A1A9EXP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1821621:A8C75 RS05010
gene id: 1821621:A8C75_RS05010
uniprot id: A0A1A9EVI0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1821621:A8C75 RS03670
gene id: 1821621:A8C75_RS03670
uniprot id: A0A1A9EUY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1821621:A8C75 RS21080
gene id: 1821621:A8C75_RS21080
uniprot id: A0A1A9F415
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1821621:A8C75 RS03085
gene id: 1821621:A8C75_RS03085
uniprot id: A0A1A9EV76
names: Similarity
messages: Belongs to the GcvT family.

1821621:A8C75 RS06170
gene id: 1821621:A8C75_RS06170
uniprot id: A0A1A9EW88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1821621:A8C75 RS21835
gene id: 1821621:A8C75_RS21835
uniprot id: A0A1A9F3R6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1821621:A8C75 RS09475
gene id: 1821621:A8C75_RS09475
uniprot id: A0A1A9EYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS23810
gene id: 1821621:A8C75_RS23810
uniprot id: A0A1A9EXF1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1821621:A8C75 RS08095
gene id: 1821621:A8C75_RS08095
uniprot id: A0A1A9EXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1821621:A8C75 RS13510
gene id: 1821621:A8C75_RS13510
uniprot id: A0A1A9EZ60
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1821621:A8C75 RS13820
gene id: 1821621:A8C75_RS13820
uniprot id: A0A1A9F0B6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS14655
gene id: 1821621:A8C75_RS14655
uniprot id: A0A1A9F6B4
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS07695
gene id: 1821621:A8C75_RS07695
uniprot id: A0A1A9EXZ0
names: Similarity
messages: Belongs to the ModE family.

1821621:A8C75 RS13095
gene id: 1821621:A8C75_RS13095
uniprot id: A0A1A9F0N8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1821621:A8C75 RS12155
gene id: 1821621:A8C75_RS12155
uniprot id: A0A1A9F049
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1821621:A8C75 RS13675
gene id: 1821621:A8C75_RS13675
uniprot id: A0A1A9F0Z6
names: Similarity
messages: Belongs to the TPP enzyme family.

1821621:A8C75 RS21655
gene id: 1821621:A8C75_RS21655
uniprot id: A0A1A9F524
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS08955
gene id: 1821621:A8C75_RS08955
uniprot id: A0A1A9EXK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1821621:A8C75 RS17605
gene id: 1821621:A8C75_RS17605
uniprot id: A0A1A9F1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1821621:A8C75 RS03950
gene id: 1821621:A8C75_RS03950
uniprot id: A0A1A9EVP5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1821621:A8C75 RS10975
gene id: 1821621:A8C75_RS10975
uniprot id: A0A1A9EZM8
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS02920
gene id: 1821621:A8C75_RS02920
uniprot id: A0A1A9EUL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1821621:A8C75 RS12785
gene id: 1821621:A8C75_RS12785
uniprot id: A0A1A9F042
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1821621:A8C75 RS02390
gene id: 1821621:A8C75_RS02390
uniprot id: A0A1A9EV42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1821621:A8C75 RS07145
gene id: 1821621:A8C75_RS07145
uniprot id: A0A1A9EXN2
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS12320
gene id: 1821621:A8C75_RS12320
uniprot id: A0A1A9EZW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS02385
gene id: 1821621:A8C75_RS02385
uniprot id: A0A1A9EUU6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1821621:A8C75 RS08015
gene id: 1821621:A8C75_RS08015
uniprot id: A0A1A9EX58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1821621:A8C75 RS22645
gene id: 1821621:A8C75_RS22645
uniprot id: A0A1A9F4U4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1821621:A8C75 RS14355
gene id: 1821621:A8C75_RS14355
uniprot id: A0A1A9F017
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS16685
gene id: 1821621:A8C75_RS16685
uniprot id: A0A1A9F4T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1821621:A8C75 RS03235
gene id: 1821621:A8C75_RS03235
uniprot id: A0A1A9EUL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1821621:A8C75 RS00735
gene id: 1821621:A8C75_RS00735
uniprot id: A0A1A9ETA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1821621:A8C75 RS03615
gene id: 1821621:A8C75_RS03615
uniprot id: A0A1A9EVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1821621:A8C75 RS01205
gene id: 1821621:A8C75_RS01205
uniprot id: A0A1A9ETZ6
names: Similarity
messages: Belongs to the UPF0111 family.

1821621:A8C75 RS18335
gene id: 1821621:A8C75_RS18335
uniprot id: A0A1A9F230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS08490
gene id: 1821621:A8C75_RS08490
uniprot id: A0A1A9EXJ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS12285
gene id: 1821621:A8C75_RS12285
uniprot id: A0A1A9EZT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1821621:A8C75 RS00380
gene id: 1821621:A8C75_RS00380
uniprot id: A0A1A9ETJ6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1821621:A8C75 RS19425
gene id: 1821621:A8C75_RS19425
uniprot id: A0A1A9F2I3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS04740
gene id: 1821621:A8C75_RS04740
uniprot id: A0A1A9EVD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1821621:A8C75 RS13200
gene id: 1821621:A8C75_RS13200
uniprot id: A0A1A9EZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS02650
gene id: 1821621:A8C75_RS02650
uniprot id: A0A1A9EU97
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS16140
gene id: 1821621:A8C75_RS16140
uniprot id: A0A1A9F181
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS14525
gene id: 1821621:A8C75_RS14525
uniprot id: A0A1A9F127
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS16160
gene id: 1821621:A8C75_RS16160
uniprot id: A0A1A9F0X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS16625
gene id: 1821621:A8C75_RS16625
uniprot id: A0A1A9F2H2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS21575
gene id: 1821621:A8C75_RS21575
uniprot id: A0A1A9F4X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS09200
gene id: 1821621:A8C75_RS09200
uniprot id: A0A1A9EY22
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS20220
gene id: 1821621:A8C75_RS20220
uniprot id: A0A1A9F2X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1821621:A8C75 RS12380
gene id: 1821621:A8C75_RS12380
uniprot id: A0A1A9F085
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS09675
gene id: 1821621:A8C75_RS09675
uniprot id: A0A1A9EX51
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS22035
gene id: 1821621:A8C75_RS22035
uniprot id: A0A1A9F3J7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS06990
gene id: 1821621:A8C75_RS06990
uniprot id: A0A1A9EWS1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS04200
gene id: 1821621:A8C75_RS04200
uniprot id: A0A1A9EV23
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1821621:A8C75 RS06375
gene id: 1821621:A8C75_RS06375
uniprot id: A0A1A9EX95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1821621:A8C75 RS22745
gene id: 1821621:A8C75_RS22745
uniprot id: A0A1A9F465
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1821621:A8C75 RS11965
gene id: 1821621:A8C75_RS11965
uniprot id: A0A1A9EYZ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS01125
gene id: 1821621:A8C75_RS01125
uniprot id: A0A1A9ETI5
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1821621:A8C75 RS01935
gene id: 1821621:A8C75_RS01935
uniprot id: A0A1A9ET55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1821621:A8C75 RS22710
gene id: 1821621:A8C75_RS22710
uniprot id: A0A1A9F579
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1821621:A8C75 RS04510
gene id: 1821621:A8C75_RS04510
uniprot id: A0A1A9EW00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1821621:A8C75 RS12450
gene id: 1821621:A8C75_RS12450
uniprot id: A0A1A9F0C5
names: Similarity
messages: Belongs to the RuBisCO large chain family.

1821621:A8C75 RS03140
gene id: 1821621:A8C75_RS03140
uniprot id: A0A1A9EV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1821621:A8C75 RS07390
gene id: 1821621:A8C75_RS07390
uniprot id: A0A1A9EWU6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1821621:A8C75 RS14415
gene id: 1821621:A8C75_RS14415
uniprot id: A0A1A9F081
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1821621:A8C75 RS11035
gene id: 1821621:A8C75_RS11035
uniprot id: A0A1A9EYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS17865
gene id: 1821621:A8C75_RS17865
uniprot id: A0A1A9F222
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS17160
gene id: 1821621:A8C75_RS17160
uniprot id: A0A1A9F2B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1821621:A8C75 RS14400
gene id: 1821621:A8C75_RS14400
uniprot id: A0A1A9EZP7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1821621:A8C75 RS01865
gene id: 1821621:A8C75_RS01865
uniprot id: A0A1A9EUL1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS04730
gene id: 1821621:A8C75_RS04730
uniprot id: A0A1A9EUL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS09190
gene id: 1821621:A8C75_RS09190
uniprot id: A0A1A9EYB2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1821621:A8C75 RS05920
gene id: 1821621:A8C75_RS05920
uniprot id: A0A1A9EV74
names: Similarity
messages: Belongs to the UPF0234 family.

1821621:A8C75 RS16065
gene id: 1821621:A8C75_RS16065
uniprot id: A0A1A9F252
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1821621:A8C75 RS04015
gene id: 1821621:A8C75_RS04015
uniprot id: A0A1A9EVA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1821621:A8C75 RS22255
gene id: 1821621:A8C75_RS22255
uniprot id: A0A1A9F504
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1821621:A8C75 RS02735
gene id: 1821621:A8C75_RS02735
uniprot id: A0A1A9EV31
names: Similarity
messages: Belongs to the PhoH family.

1821621:A8C75 RS19625
gene id: 1821621:A8C75_RS19625
uniprot id: A0A1A9F3N1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS02455
gene id: 1821621:A8C75_RS02455
uniprot id: A0A1A9EUI2
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS04350
gene id: 1821621:A8C75_RS04350
uniprot id: A0A1A9EW80
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1821621:A8C75 RS15390
gene id: 1821621:A8C75_RS15390
uniprot id: A0A1A9F0J3
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1821621:A8C75 RS17245
gene id: 1821621:A8C75_RS17245
uniprot id: A0A1A9F4U2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1821621:A8C75 RS22550
gene id: 1821621:A8C75_RS22550
uniprot id: A0A1A9F5H5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1821621:A8C75 RS17970
gene id: 1821621:A8C75_RS17970
uniprot id: A0A1A9F247
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1821621:A8C75 RS07765
gene id: 1821621:A8C75_RS07765
uniprot id: A0A1A9EWZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1821621:A8C75 RS07685
gene id: 1821621:A8C75_RS07685
uniprot id: A0A1A9EXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1821621:A8C75 RS14565
gene id: 1821621:A8C75_RS14565
uniprot id: A0A1A9F051
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1821621:A8C75 RS17650
gene id: 1821621:A8C75_RS17650
uniprot id: A0A1A9F198
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1821621:A8C75 RS02235
gene id: 1821621:A8C75_RS02235
uniprot id: A0A1A9EUT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS20630
gene id: 1821621:A8C75_RS20630
uniprot id: A0A1A9F3I6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1821621:A8C75 RS14990
gene id: 1821621:A8C75_RS14990
uniprot id: A0A1A9F186
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1821621:A8C75 RS02365
gene id: 1821621:A8C75_RS02365
uniprot id: A0A1A9ETE3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1821621:A8C75 RS02720
gene id: 1821621:A8C75_RS02720
uniprot id: A0A1A9EV09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS21175
gene id: 1821621:A8C75_RS21175
uniprot id: A0A1A9F4Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1821621:A8C75 RS14700
gene id: 1821621:A8C75_RS14700
uniprot id: A0A1A9F1G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1821621:A8C75 RS07515
gene id: 1821621:A8C75_RS07515
uniprot id: A0A1A9EX07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1821621:A8C75 RS13070
gene id: 1821621:A8C75_RS13070
uniprot id: A0A1A9F0K3
names: Similarity
messages: Belongs to the thioredoxin family.

1821621:A8C75 RS03300
gene id: 1821621:A8C75_RS03300
uniprot id: A0A1A9EUM5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1821621:A8C75 RS19820
gene id: 1821621:A8C75_RS19820
uniprot id: A0A1A9F2Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1821621:A8C75 RS15020
gene id: 1821621:A8C75_RS15020
uniprot id: A0A1A9F0J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS21875
gene id: 1821621:A8C75_RS21875
uniprot id: A0A1A9F3G9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1821621:A8C75 RS09995
gene id: 1821621:A8C75_RS09995
uniprot id: A0A1A9EZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS15730
gene id: 1821621:A8C75_RS15730
uniprot id: A0A1A9F207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1821621:A8C75 RS20610
gene id: 1821621:A8C75_RS20610
uniprot id: A0A1A9F4F6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1821621:A8C75 RS16095
gene id: 1821621:A8C75_RS16095
uniprot id: A0A1A9F0H2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1821621:A8C75 RS11315
gene id: 1821621:A8C75_RS11315
uniprot id: A0A1A9EZQ3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1821621:A8C75 RS04930
gene id: 1821621:A8C75_RS04930
uniprot id: A0A1A9EW77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1821621:A8C75 RS01800
gene id: 1821621:A8C75_RS01800
uniprot id: A0A1A9EUA6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1821621:A8C75 RS20380
gene id: 1821621:A8C75_RS20380
uniprot id: A0A1A9F349
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1821621:A8C75 RS21060
gene id: 1821621:A8C75_RS21060
uniprot id: A0A1A9F3B0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1821621:A8C75 RS16780
gene id: 1821621:A8C75_RS16780
uniprot id: A0A1A9F2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1821621:A8C75 RS11065
gene id: 1821621:A8C75_RS11065
uniprot id: A0A1A9F0E2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1821621:A8C75 RS12115
gene id: 1821621:A8C75_RS12115
uniprot id: A0A1A9EZ78
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1821621:A8C75 RS11565
gene id: 1821621:A8C75_RS11565
uniprot id: A0A1A9EYM2
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1821621:A8C75 RS06425
gene id: 1821621:A8C75_RS06425
uniprot id: A0A1A9EXA7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS01155
gene id: 1821621:A8C75_RS01155
uniprot id: A0A1A9EU82
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1821621:A8C75 RS06190
gene id: 1821621:A8C75_RS06190
uniprot id: A0A1A9EWW5
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1821621:A8C75 RS16495
gene id: 1821621:A8C75_RS16495
uniprot id: A0A1A9F177
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS19255
gene id: 1821621:A8C75_RS19255
uniprot id: A0A1A9F2E7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1821621:A8C75 RS12340
gene id: 1821621:A8C75_RS12340
uniprot id: A0A1A9EZB4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1821621:A8C75 RS02760
gene id: 1821621:A8C75_RS02760
uniprot id: A0A1A9EUB7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1821621:A8C75 RS02590
gene id: 1821621:A8C75_RS02590
uniprot id: A0A1A9EU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1821621:A8C75 RS03210
gene id: 1821621:A8C75_RS03210
uniprot id: A0A1A9EVC1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS17915
gene id: 1821621:A8C75_RS17915
uniprot id: A0A1A9F2S1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS01345
gene id: 1821621:A8C75_RS01345
uniprot id: A0A1A9ETK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS17355
gene id: 1821621:A8C75_RS17355
uniprot id: A0A1A9F540
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1821621:A8C75 RS09275
gene id: 1821621:A8C75_RS09275
uniprot id: A0A1A9EYU4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1821621:A8C75 RS15195
gene id: 1821621:A8C75_RS15195
uniprot id: A0A1A9F115
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1821621:A8C75 RS05805
gene id: 1821621:A8C75_RS05805
uniprot id: A0A1A9EV60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1821621:A8C75 RS03895
gene id: 1821621:A8C75_RS03895
uniprot id: A0A1A9EVB6
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1821621:A8C75 RS08045
gene id: 1821621:A8C75_RS08045
uniprot id: A0A1A9EY52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1821621:A8C75 RS20135
gene id: 1821621:A8C75_RS20135
uniprot id: A0A1A9F3Y1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

1821621:A8C75 RS15055
gene id: 1821621:A8C75_RS15055
uniprot id: A0A1A9F008
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1821621:A8C75 RS21755
gene id: 1821621:A8C75_RS21755
uniprot id: A0A1A9F4R7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1821621:A8C75 RS12375
gene id: 1821621:A8C75_RS12375
uniprot id: A0A1A9EZX4
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS12730
gene id: 1821621:A8C75_RS12730
uniprot id: A0A1A9F032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

1821621:A8C75 RS18555
gene id: 1821621:A8C75_RS18555
uniprot id: A0A1A9F3F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1821621:A8C75 RS02090
gene id: 1821621:A8C75_RS02090
uniprot id: A0A1A9EV08
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1821621:A8C75 RS15680
gene id: 1821621:A8C75_RS15680
uniprot id: A0A1A9F195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1821621:A8C75 RS15010
gene id: 1821621:A8C75_RS15010
uniprot id: A0A1A9F0H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS22755
gene id: 1821621:A8C75_RS22755
uniprot id: A0A1A9F5I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1821621:A8C75 RS09680
gene id: 1821621:A8C75_RS09680
uniprot id: A0A1A9EXV4
names: Similarity
messages: Belongs to the arginase family.

1821621:A8C75 RS04055
gene id: 1821621:A8C75_RS04055
uniprot id: A0A1A9EVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1821621:A8C75 RS14720
gene id: 1821621:A8C75_RS14720
uniprot id: A0A1A9F0J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS08675
gene id: 1821621:A8C75_RS08675
uniprot id: A0A1A9EY50
names: Similarity
messages: Belongs to the SCO1/2 family.

1821621:A8C75 RS07520
gene id: 1821621:A8C75_RS07520
uniprot id: A0A1A9EXW2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1821621:A8C75 RS05160
gene id: 1821621:A8C75_RS05160
uniprot id: A0A1A9EUU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1821621:A8C75 RS08055
gene id: 1821621:A8C75_RS08055
uniprot id: A0A1A9EX45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

1821621:A8C75 RS15605
gene id: 1821621:A8C75_RS15605
uniprot id: A0A1A9F0T7
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS03725
gene id: 1821621:A8C75_RS03725
uniprot id: A0A1A9EUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS19170
gene id: 1821621:A8C75_RS19170
uniprot id: A0A1A9F326
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1821621:A8C75 RS12850
gene id: 1821621:A8C75_RS12850
uniprot id: A0A1A9EZU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS02995
gene id: 1821621:A8C75_RS02995
uniprot id: A0A1A9EV81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1821621:A8C75 RS05015
gene id: 1821621:A8C75_RS05015
uniprot id: A0A1A9EVN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS01045
gene id: 1821621:A8C75_RS01045
uniprot id: A0A1A9ETW7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1821621:A8C75 RS22655
gene id: 1821621:A8C75_RS22655
uniprot id: A0A1A9F4K0
names: Similarity
messages: Belongs to the arginase family.

1821621:A8C75 RS16100
gene id: 1821621:A8C75_RS16100
uniprot id: A0A1A9F0Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS04305
gene id: 1821621:A8C75_RS04305
uniprot id: A0A1A9EV48
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1821621:A8C75 RS04230
gene id: 1821621:A8C75_RS04230
uniprot id: A0A1A9EVU6
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1821621:A8C75 RS12390
gene id: 1821621:A8C75_RS12390
uniprot id: A0A1A9EZV6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1821621:A8C75 RS06105
gene id: 1821621:A8C75_RS06105
uniprot id: A0A1A9EW17
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1821621:A8C75 RS17490
gene id: 1821621:A8C75_RS17490
uniprot id: A0A1A9F169
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1821621:A8C75 RS19550
gene id: 1821621:A8C75_RS19550
uniprot id: A0A1A9F3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1821621:A8C75 RS19240
gene id: 1821621:A8C75_RS19240
uniprot id: A0A1A9F3T6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1821621:A8C75 RS21075
gene id: 1821621:A8C75_RS21075
uniprot id: A0A1A9F4N6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1821621:A8C75 RS13005
gene id: 1821621:A8C75_RS13005
uniprot id: A0A1A9F0J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1821621:A8C75 RS05070
gene id: 1821621:A8C75_RS05070
uniprot id: A0A1A9EW75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1821621:A8C75 RS03215
gene id: 1821621:A8C75_RS03215
uniprot id: A0A1A9F5P4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1821621:A8C75 RS01915
gene id: 1821621:A8C75_RS01915
uniprot id: A0A1A9EUC3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1821621:A8C75 RS09630
gene id: 1821621:A8C75_RS09630
uniprot id: A0A1A9EXR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Vgb family.
messages: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
messages: Monomer.

1821621:A8C75 RS19750
gene id: 1821621:A8C75_RS19750
uniprot id: A0A1A9F431
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1821621:A8C75 RS01860
gene id: 1821621:A8C75_RS01860
uniprot id: A0A1A9EUB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS19305
gene id: 1821621:A8C75_RS19305
uniprot id: A0A1A9F2L4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1821621:A8C75 RS20910
gene id: 1821621:A8C75_RS20910
uniprot id: A0A1A9F3Y5
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS19435
gene id: 1821621:A8C75_RS19435
uniprot id: A0A1A9F3G5
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS02785
gene id: 1821621:A8C75_RS02785
uniprot id: A0A1A9EV44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1821621:A8C75 RS16405
gene id: 1821621:A8C75_RS16405
uniprot id: A0A1A9F1Y3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS04575
gene id: 1821621:A8C75_RS04575
uniprot id: A0A1A9EUJ3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1821621:A8C75 RS20955
gene id: 1821621:A8C75_RS20955
uniprot id: A0A1A9F4L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1821621:A8C75 RS05765
gene id: 1821621:A8C75_RS05765
uniprot id: A0A1A9EVV8
names: Subcellular Location Annotation
messages: Cytoplasm

1821621:A8C75 RS00055
gene id: 1821621:A8C75_RS00055
uniprot id: A0A1A9F4N0
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS18575
gene id: 1821621:A8C75_RS18575
uniprot id: A0A1A9F220
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS20650
gene id: 1821621:A8C75_RS20650
uniprot id: A0A1A9F350
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS04470
gene id: 1821621:A8C75_RS04470
uniprot id: A0A1A9F5G7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1821621:A8C75 RS16975
gene id: 1821621:A8C75_RS16975
uniprot id: A0A1A9F0X2
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS04205
gene id: 1821621:A8C75_RS04205
uniprot id: A0A1A9F4F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1821621:A8C75 RS11150
gene id: 1821621:A8C75_RS11150
uniprot id: A0A1A9EYM0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1821621:A8C75 RS10095
gene id: 1821621:A8C75_RS10095
uniprot id: A0A1A9EY37
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS12425
gene id: 1821621:A8C75_RS12425
uniprot id: A0A1A9EZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS22380
gene id: 1821621:A8C75_RS22380
uniprot id: A0A1A9F525
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS16840
gene id: 1821621:A8C75_RS16840
uniprot id: A0A1A9F1V0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS24170
gene id: 1821621:A8C75_RS24170
uniprot id: A0A1A9EV00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1821621:A8C75 RS02585
gene id: 1821621:A8C75_RS02585
uniprot id: A0A1A9EUA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1821621:A8C75 RS17190
gene id: 1821621:A8C75_RS17190
uniprot id: A0A1A9F6H0
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1821621:A8C75 RS05785
gene id: 1821621:A8C75_RS05785
uniprot id: A0A1A9EWC8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1821621:A8C75 RS05965
gene id: 1821621:A8C75_RS05965
uniprot id: A0A1A9EX21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS05335
gene id: 1821621:A8C75_RS05335
uniprot id: A0A1A9EVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS03815
gene id: 1821621:A8C75_RS03815
uniprot id: A0A1A9EU62
names: Similarity
messages: Belongs to the DapA family.

1821621:A8C75 RS01505
gene id: 1821621:A8C75_RS01505
uniprot id: A0A1A9ETN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1821621:A8C75 RS07900
gene id: 1821621:A8C75_RS07900
uniprot id: A0A1A9EY11
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1821621:A8C75 RS19760
gene id: 1821621:A8C75_RS19760
uniprot id: A0A1A9F2U1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1821621:A8C75 RS08165
gene id: 1821621:A8C75_RS08165
uniprot id: A0A1A9EWE3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1821621:A8C75 RS11670
gene id: 1821621:A8C75_RS11670
uniprot id: A0A1A9EY45
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1821621:A8C75 RS08185
gene id: 1821621:A8C75_RS08185
uniprot id: A0A1A9EXT3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1821621:A8C75 RS08205
gene id: 1821621:A8C75_RS08205
uniprot id: A0A1A9EXD2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1821621:A8C75 RS21485
gene id: 1821621:A8C75_RS21485
uniprot id: A0A1A9F3I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1821621:A8C75 RS13730
gene id: 1821621:A8C75_RS13730
uniprot id: A0A1A9F107
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1821621:A8C75 RS19770
gene id: 1821621:A8C75_RS19770
uniprot id: A0A1A9F2R5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS12705
gene id: 1821621:A8C75_RS12705
uniprot id: A0A1A9EYQ3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1821621:A8C75 RS18400
gene id: 1821621:A8C75_RS18400
uniprot id: A0A1A9F399
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1821621:A8C75 RS10345
gene id: 1821621:A8C75_RS10345
uniprot id: A0A1A9EYW2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS10645
gene id: 1821621:A8C75_RS10645
uniprot id: A0A1A9EY92
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1821621:A8C75 RS01460
gene id: 1821621:A8C75_RS01460
uniprot id: A0A1A9EUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1821621:A8C75 RS13385
gene id: 1821621:A8C75_RS13385
uniprot id: A0A1A9F0U2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1821621:A8C75 RS20350
gene id: 1821621:A8C75_RS20350
uniprot id: A0A1A9F3P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1821621:A8C75 RS02370
gene id: 1821621:A8C75_RS02370
uniprot id: A0A1A9EU63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1821621:A8C75 RS17460
gene id: 1821621:A8C75_RS17460
uniprot id: A0A1A9F2G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1821621:A8C75 RS12150
gene id: 1821621:A8C75_RS12150
uniprot id: A0A1A9EZT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1821621:A8C75 RS12855
gene id: 1821621:A8C75_RS12855
uniprot id: A0A1A9F041
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS08990
gene id: 1821621:A8C75_RS08990
uniprot id: A0A1A9EWT8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1821621:A8C75 RS02580
gene id: 1821621:A8C75_RS02580
uniprot id: A0A1A9ETI6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1821621:A8C75 RS22245
gene id: 1821621:A8C75_RS22245
uniprot id: A0A1A9F588
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1821621:A8C75 RS04290
gene id: 1821621:A8C75_RS04290
uniprot id: A0A1A9EVF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1821621:A8C75 RS14345
gene id: 1821621:A8C75_RS14345
uniprot id: A0A1A9EZN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1821621:A8C75 RS14910
gene id: 1821621:A8C75_RS14910
uniprot id: A0A1A9F0H3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1821621:A8C75 RS10090
gene id: 1821621:A8C75_RS10090
uniprot id: A0A1A9EXZ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS21320
gene id: 1821621:A8C75_RS21320
uniprot id: A0A1A9F372
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1821621:A8C75 RS04430
gene id: 1821621:A8C75_RS04430
uniprot id: A0A1A9EVV9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1821621:A8C75 RS13505
gene id: 1821621:A8C75_RS13505
uniprot id: A0A1A9F0W5
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1821621:A8C75 RS17655
gene id: 1821621:A8C75_RS17655
uniprot id: A0A1A9F1T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS20270
gene id: 1821621:A8C75_RS20270
uniprot id: A0A1A9F2Y4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS02740
gene id: 1821621:A8C75_RS02740
uniprot id: A0A1A9EUN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1821621:A8C75 RS22305
gene id: 1821621:A8C75_RS22305
uniprot id: A0A1A9F599
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1821621:A8C75 RS14765
gene id: 1821621:A8C75_RS14765
uniprot id: A0A1A9F0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1821621:A8C75 RS18960
gene id: 1821621:A8C75_RS18960
uniprot id: A0A1A9F636
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1821621:A8C75 RS15060
gene id: 1821621:A8C75_RS15060
uniprot id: A0A1A9F0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1821621:A8C75 RS02345
gene id: 1821621:A8C75_RS02345
uniprot id: A0A1A9EUV8
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1821621:A8C75 RS14535
gene id: 1821621:A8C75_RS14535
uniprot id: A0A1A9F0Q1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS06610
gene id: 1821621:A8C75_RS06610
uniprot id: A0A1A9EWG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1821621:A8C75 RS02905
gene id: 1821621:A8C75_RS02905
uniprot id: A0A1A9ETR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1821621:A8C75 RS12545
gene id: 1821621:A8C75_RS12545
uniprot id: A0A1A9EZP9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1821621:A8C75 RS11410
gene id: 1821621:A8C75_RS11410
uniprot id: A0A1A9EZD5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1821621:A8C75 RS08610
gene id: 1821621:A8C75_RS08610
uniprot id: A0A1A9EY40
names: Similarity
messages: Belongs to the BolA/IbaG family.

1821621:A8C75 RS04560
gene id: 1821621:A8C75_RS04560
uniprot id: A0A1A9EW10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1821621:A8C75 RS21395
gene id: 1821621:A8C75_RS21395
uniprot id: A0A1A9F4U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1821621:A8C75 RS22725
gene id: 1821621:A8C75_RS22725
uniprot id: A0A1A9F3W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1821621:A8C75 RS08735
gene id: 1821621:A8C75_RS08735
uniprot id: A0A1A9F5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS04005
gene id: 1821621:A8C75_RS04005
uniprot id: A0A1A9EVD4
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1821621:A8C75 RS11520
gene id: 1821621:A8C75_RS11520
uniprot id: A0A1A9EYS4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1821621:A8C75 RS11365
gene id: 1821621:A8C75_RS11365
uniprot id: A0A1A9EZF3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS03290
gene id: 1821621:A8C75_RS03290
uniprot id: A0A1A9EVQ1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS00775
gene id: 1821621:A8C75_RS00775
uniprot id: A0A1A9ETM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS21390
gene id: 1821621:A8C75_RS21390
uniprot id: A0A1A9F4G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1821621:A8C75 RS10540
gene id: 1821621:A8C75_RS10540
uniprot id: A0A1A9EY72
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1821621:A8C75 RS12910
gene id: 1821621:A8C75_RS12910
uniprot id: A0A1A9F050
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1821621:A8C75 RS06400
gene id: 1821621:A8C75_RS06400
uniprot id: A0A1A9EWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS00865
gene id: 1821621:A8C75_RS00865
uniprot id: A0A1A9ETC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS03845
gene id: 1821621:A8C75_RS03845
uniprot id: A0A1A9EVA6
names: Similarity
messages: Belongs to the PrpD family.

1821621:A8C75 RS22350
gene id: 1821621:A8C75_RS22350
uniprot id: A0A1A9F438
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1821621:A8C75 RS11555
gene id: 1821621:A8C75_RS11555
uniprot id: A0A1A9EY25
names: Similarity
messages: Belongs to the histone deacetylase family.

1821621:A8C75 RS02565
gene id: 1821621:A8C75_RS02565
uniprot id: A0A1A9EUZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1821621:A8C75 RS21350
gene id: 1821621:A8C75_RS21350
uniprot id: A0A1A9F464
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1821621:A8C75 RS04695
gene id: 1821621:A8C75_RS04695
uniprot id: A0A1A9EW08
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1821621:A8C75 RS05170
gene id: 1821621:A8C75_RS05170
uniprot id: A0A1A9EVK6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1821621:A8C75 RS12120
gene id: 1821621:A8C75_RS12120
uniprot id: A0A1A9F066
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS12280
gene id: 1821621:A8C75_RS12280
uniprot id: A0A1A9F591
names: Similarity
messages: Belongs to the peptidase S11 family.

1821621:A8C75 RS01325
gene id: 1821621:A8C75_RS01325
uniprot id: A0A1A9ETX2
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS06490
gene id: 1821621:A8C75_RS06490
uniprot id: A0A1A9EWC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS09795
gene id: 1821621:A8C75_RS09795
uniprot id: A0A1A9EX71
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS17225
gene id: 1821621:A8C75_RS17225
uniprot id: A0A1A9F226
names: Similarity
messages: Belongs to the UPF0229 family.

1821621:A8C75 RS05090
gene id: 1821621:A8C75_RS05090
uniprot id: A0A1A9EVT6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1821621:A8C75 RS00270
gene id: 1821621:A8C75_RS00270
uniprot id: A0A1A9ETZ4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1821621:A8C75 RS18855
gene id: 1821621:A8C75_RS18855
uniprot id: A0A1A9F3I5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS14365
gene id: 1821621:A8C75_RS14365
uniprot id: A0A1A9F102
names: Similarity
messages: Belongs to the agmatine deiminase family.

1821621:A8C75 RS13805
gene id: 1821621:A8C75_RS13805
uniprot id: A0A1A9EZX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS06035
gene id: 1821621:A8C75_RS06035
uniprot id: A0A1A9EX31
names: Subunit
messages: Homotetramer.

1821621:A8C75 RS22480
gene id: 1821621:A8C75_RS22480
uniprot id: A0A1A9F546
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1821621:A8C75 RS02755
gene id: 1821621:A8C75_RS02755
uniprot id: A0A1A9EUC4
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1821621:A8C75 RS21190
gene id: 1821621:A8C75_RS21190
uniprot id: A0A1A9F5Y6
names: Similarity
messages: Belongs to the allantoicase family.

1821621:A8C75 RS22395
gene id: 1821621:A8C75_RS22395
uniprot id: A0A1A9F3Q5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1821621:A8C75 RS06245
gene id: 1821621:A8C75_RS06245
uniprot id: A0A1A9EWX5
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

1821621:A8C75 RS04345
gene id: 1821621:A8C75_RS04345
uniprot id: A0A1A9EVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1821621:A8C75 RS14370
gene id: 1821621:A8C75_RS14370
uniprot id: A0A1A9F1A3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS07675
gene id: 1821621:A8C75_RS07675
uniprot id: A0A1A9EXX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1821621:A8C75 RS18695
gene id: 1821621:A8C75_RS18695
uniprot id: A0A1A9F2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1821621:A8C75 RS21750
gene id: 1821621:A8C75_RS21750
uniprot id: A0A1A9F4D6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1821621:A8C75 RS00460
gene id: 1821621:A8C75_RS00460
uniprot id: A0A1A9ESB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS09205
gene id: 1821621:A8C75_RS09205
uniprot id: A0A1A9EYD2
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1821621:A8C75 RS20805
gene id: 1821621:A8C75_RS20805
uniprot id: A0A1A9F3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS06330
gene id: 1821621:A8C75_RS06330
uniprot id: A0A1A9EW57
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1821621:A8C75 RS05280
gene id: 1821621:A8C75_RS05280
uniprot id: A0A1A9EVN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1821621:A8C75 RS00845
gene id: 1821621:A8C75_RS00845
uniprot id: A0A1A9EUD0
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS01140
gene id: 1821621:A8C75_RS01140
uniprot id: A0A1A9EU68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1821621:A8C75 RS09245
gene id: 1821621:A8C75_RS09245
uniprot id: A0A1A9EYC1
names: Similarity
messages: Belongs to the PrpF family.

1821621:A8C75 RS22605
gene id: 1821621:A8C75_RS22605
uniprot id: A0A1A9F4I9
names: Similarity
messages: Belongs to the IucA/IucC family.

1821621:A8C75 RS15350
gene id: 1821621:A8C75_RS15350
uniprot id: A0A1A9F1H1
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1821621:A8C75 RS01855
gene id: 1821621:A8C75_RS01855
uniprot id: A0A1A9EUT8
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1821621:A8C75 RS06270
gene id: 1821621:A8C75_RS06270
uniprot id: A0A1A9EW44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1821621:A8C75 RS04515
gene id: 1821621:A8C75_RS04515
uniprot id: A0A1A9EVI2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1821621:A8C75 RS04835
gene id: 1821621:A8C75_RS04835
uniprot id: A0A1A9EVF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS16700
gene id: 1821621:A8C75_RS16700
uniprot id: A0A1A9F0S2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1821621:A8C75 RS14130
gene id: 1821621:A8C75_RS14130
uniprot id: A0A1A9EZI5
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS07945
gene id: 1821621:A8C75_RS07945
uniprot id: A0A1A9EWY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1821621:A8C75 RS04755
gene id: 1821621:A8C75_RS04755
uniprot id: A0A1A9EWE2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1821621:A8C75 RS13750
gene id: 1821621:A8C75_RS13750
uniprot id: A0A1A9EZW1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS08040
gene id: 1821621:A8C75_RS08040
uniprot id: A0A1A9EX97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1821621:A8C75 RS22095
gene id: 1821621:A8C75_RS22095
uniprot id: A0A1A9F4J3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS06015
gene id: 1821621:A8C75_RS06015
uniprot id: A0A1A9EWG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1821621:A8C75 RS17730
gene id: 1821621:A8C75_RS17730
uniprot id: A0A1A9F2L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS10620
gene id: 1821621:A8C75_RS10620
uniprot id: A0A1A9EZ07
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1821621:A8C75 RS10555
gene id: 1821621:A8C75_RS10555
uniprot id: A0A1A9EZC4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS07160
gene id: 1821621:A8C75_RS07160
uniprot id: A0A1A9EWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1821621:A8C75 RS10560
gene id: 1821621:A8C75_RS10560
uniprot id: A0A1A9EYR0
names: Similarity
messages: Belongs to the TPP enzyme family.

1821621:A8C75 RS12170
gene id: 1821621:A8C75_RS12170
uniprot id: A0A1A9EZ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1821621:A8C75 RS06600
gene id: 1821621:A8C75_RS06600
uniprot id: A0A1A9EWD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1821621:A8C75 RS01480
gene id: 1821621:A8C75_RS01480
uniprot id: A0A1A9EUE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1821621:A8C75 RS04665
gene id: 1821621:A8C75_RS04665
uniprot id: A0A1A9EVL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS12820
gene id: 1821621:A8C75_RS12820
uniprot id: A0A1A9EZD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1821621:A8C75 RS17535
gene id: 1821621:A8C75_RS17535
uniprot id: A0A1A9F2Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1821621:A8C75 RS19110
gene id: 1821621:A8C75_RS19110
uniprot id: A0A1A9F665
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1821621:A8C75 RS12260
gene id: 1821621:A8C75_RS12260
uniprot id: A0A1A9EZV7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1821621:A8C75 RS22190
gene id: 1821621:A8C75_RS22190
uniprot id: A0A1A9F580
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1821621:A8C75 RS12200
gene id: 1821621:A8C75_RS12200
uniprot id: A0A1A9EZ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS04720
gene id: 1821621:A8C75_RS04720
uniprot id: A0A1A9EVM5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1821621:A8C75 RS01370
gene id: 1821621:A8C75_RS01370
uniprot id: A0A1A9EUC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1821621:A8C75 RS03070
gene id: 1821621:A8C75_RS03070
uniprot id: A0A1A9EUI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS22425
gene id: 1821621:A8C75_RS22425
uniprot id: A0A1A9F4Q8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1821621:A8C75 RS10915
gene id: 1821621:A8C75_RS10915
uniprot id: A0A1A9EXS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS06655
gene id: 1821621:A8C75_RS06655
uniprot id: A0A1A9EVL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS04160
gene id: 1821621:A8C75_RS04160
uniprot id: A0A1A9EVQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1821621:A8C75 RS17885
gene id: 1821621:A8C75_RS17885
uniprot id: A0A1A9F1Q4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS17950
gene id: 1821621:A8C75_RS17950
uniprot id: A0A1A9F2Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1821621:A8C75 RS03905
gene id: 1821621:A8C75_RS03905
uniprot id: A0A1A9EV80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS12290
gene id: 1821621:A8C75_RS12290
uniprot id: A0A1A9EZA5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1821621:A8C75 RS21415
gene id: 1821621:A8C75_RS21415
uniprot id: A0A1A9F4Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1821621:A8C75 RS08855
gene id: 1821621:A8C75_RS08855
uniprot id: A0A1A9EXW6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1821621:A8C75 RS05710
gene id: 1821621:A8C75_RS05710
uniprot id: A0A1A9EVX4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1821621:A8C75 RS04885
gene id: 1821621:A8C75_RS04885
uniprot id: A0A1A9EUP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

1821621:A8C75 RS02450
gene id: 1821621:A8C75_RS02450
uniprot id: A0A1A9EUY3
names: Similarity
messages: Belongs to the UPF0045 family.

1821621:A8C75 RS10030
gene id: 1821621:A8C75_RS10030
uniprot id: A0A1A9EY13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS18935
gene id: 1821621:A8C75_RS18935
uniprot id: A0A1A9F3M7
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1821621:A8C75 RS03900
gene id: 1821621:A8C75_RS03900
uniprot id: A0A1A9EVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1821621:A8C75 RS21070
gene id: 1821621:A8C75_RS21070
uniprot id: A0A1A9F4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1821621:A8C75 RS16260
gene id: 1821621:A8C75_RS16260
uniprot id: A0A1A9F0K1
names: Similarity
messages: Belongs to the CdaR family.

1821621:A8C75 RS18245
gene id: 1821621:A8C75_RS18245
uniprot id: A0A1A9F2Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS13155
gene id: 1821621:A8C75_RS13155
uniprot id: A0A1A9F0Q0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS21715
gene id: 1821621:A8C75_RS21715
uniprot id: A0A1A9F533
names: Similarity
messages: Belongs to the thioredoxin family.

1821621:A8C75 RS07525
gene id: 1821621:A8C75_RS07525
uniprot id: A0A1A9EW26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1821621:A8C75 RS04890
gene id: 1821621:A8C75_RS04890
uniprot id: A0A1A9EVG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

1821621:A8C75 RS18320
gene id: 1821621:A8C75_RS18320
uniprot id: A0A1A9F1M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS00190
gene id: 1821621:A8C75_RS00190
uniprot id: A0A1A9ETP7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1821621:A8C75 RS21275
gene id: 1821621:A8C75_RS21275
uniprot id: A0A1A9F3F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS02880
gene id: 1821621:A8C75_RS02880
uniprot id: A0A1A9EVF6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1821621:A8C75 RS13550
gene id: 1821621:A8C75_RS13550
uniprot id: A0A1A9F0G7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1821621:A8C75 RS04320
gene id: 1821621:A8C75_RS04320
uniprot id: A0A1A9EVT3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1821621:A8C75 RS12145
gene id: 1821621:A8C75_RS12145
uniprot id: A0A1A9EZ29
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1821621:A8C75 RS20370
gene id: 1821621:A8C75_RS20370
uniprot id: A0A1A9F2R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS14985
gene id: 1821621:A8C75_RS14985
uniprot id: A0A1A9F0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS03450
gene id: 1821621:A8C75_RS03450
uniprot id: A0A1A9EVT1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1821621:A8C75 RS11280
gene id: 1821621:A8C75_RS11280
uniprot id: A0A1A9EZT2
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

1821621:A8C75 RS03965
gene id: 1821621:A8C75_RS03965
uniprot id: A0A1A9EU91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1821621:A8C75 RS00725
gene id: 1821621:A8C75_RS00725
uniprot id: A0A1A9EUA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1821621:A8C75 RS03295
gene id: 1821621:A8C75_RS03295
uniprot id: A0A1A9ETY0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1821621:A8C75 RS03625
gene id: 1821621:A8C75_RS03625
uniprot id: A0A1A9EV69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS00925
gene id: 1821621:A8C75_RS00925
uniprot id: A0A1A9ETH3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1821621:A8C75 RS02595
gene id: 1821621:A8C75_RS02595
uniprot id: A0A1A9EUD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1821621:A8C75 RS03020
gene id: 1821621:A8C75_RS03020
uniprot id: A0A1A9EUH0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1821621:A8C75 RS03970
gene id: 1821621:A8C75_RS03970
uniprot id: A0A1A9EUY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1821621:A8C75 RS01475
gene id: 1821621:A8C75_RS01475
uniprot id: A0A1A9EU46
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1821621:A8C75 RS22320
gene id: 1821621:A8C75_RS22320
uniprot id: A0A1A9F4E1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS17910
gene id: 1821621:A8C75_RS17910
uniprot id: A0A1A9F2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1821621:A8C75 RS07165
gene id: 1821621:A8C75_RS07165
uniprot id: A0A1A9EXP1
names: Similarity
messages: Belongs to the MQO family.

1821621:A8C75 RS14395
gene id: 1821621:A8C75_RS14395
uniprot id: A0A1A9F1D6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS16080
gene id: 1821621:A8C75_RS16080
uniprot id: A0A1A9F1S6
names: Cofactor
messages: Can also use Mn(2+) ion.

1821621:A8C75 RS09160
gene id: 1821621:A8C75_RS09160
uniprot id: A0A1A9EXT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS17360
gene id: 1821621:A8C75_RS17360
uniprot id: A0A1A9F2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1821621:A8C75 RS19185
gene id: 1821621:A8C75_RS19185
uniprot id: A0A1A9F3S5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1821621:A8C75 RS16855
gene id: 1821621:A8C75_RS16855
uniprot id: A0A1A9F1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1821621:A8C75 RS21585
gene id: 1821621:A8C75_RS21585
uniprot id: A0A1A9F4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1821621:A8C75 RS00995
gene id: 1821621:A8C75_RS00995
uniprot id: A0A1A9EU51
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1821621:A8C75 RS06050
gene id: 1821621:A8C75_RS06050
uniprot id: A0A1A9EW06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1821621:A8C75 RS06780
gene id: 1821621:A8C75_RS06780
uniprot id: A0A1A9EWH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1821621:A8C75 RS21310
gene id: 1821621:A8C75_RS21310
uniprot id: A0A1A9F3V5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1821621:A8C75 RS06235
gene id: 1821621:A8C75_RS06235
uniprot id: A0A1A9EX68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS17800
gene id: 1821621:A8C75_RS17800
uniprot id: A0A1A9F2C1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1821621:A8C75 RS15175
gene id: 1821621:A8C75_RS15175
uniprot id: A0A1A9F0M5
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1821621:A8C75 RS02935
gene id: 1821621:A8C75_RS02935
uniprot id: A0A1A9EUX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1821621:A8C75 RS02510
gene id: 1821621:A8C75_RS02510
uniprot id: A0A1A9EUJ1
names: Similarity
messages: Belongs to the threonine synthase family.

1821621:A8C75 RS12005
gene id: 1821621:A8C75_RS12005
uniprot id: A0A1A9EZ54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1821621:A8C75 RS09330
gene id: 1821621:A8C75_RS09330
uniprot id: A0A1A9EYV4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1821621:A8C75 RS01220
gene id: 1821621:A8C75_RS01220
uniprot id: A0A1A9F5B7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS18010
gene id: 1821621:A8C75_RS18010
uniprot id: A0A1A9F2G2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS07995
gene id: 1821621:A8C75_RS07995
uniprot id: A0A1A9EWB1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS05490
gene id: 1821621:A8C75_RS05490
uniprot id: A0A1A9EW04
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS12830
gene id: 1821621:A8C75_RS12830
uniprot id: A0A1A9EZ97
names: Similarity
messages: Belongs to the TrpF family.

1821621:A8C75 RS22705
gene id: 1821621:A8C75_RS22705
uniprot id: A0A1A9F4V6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS10630
gene id: 1821621:A8C75_RS10630
uniprot id: A0A1A9EZH2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1821621:A8C75 RS13705
gene id: 1821621:A8C75_RS13705
uniprot id: A0A1A9F0X3
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1821621:A8C75 RS00105
gene id: 1821621:A8C75_RS00105
uniprot id: A0A1A9ETP0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1821621:A8C75 RS12475
gene id: 1821621:A8C75_RS12475
uniprot id: A0A1A9EZ99
names: Similarity
messages: Belongs to the hyi family.

1821621:A8C75 RS03015
gene id: 1821621:A8C75_RS03015
uniprot id: A0A1A9EUH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1821621:A8C75 RS14300
gene id: 1821621:A8C75_RS14300
uniprot id: A0A1A9F045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS08170
gene id: 1821621:A8C75_RS08170
uniprot id: A0A1A9EX62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1821621:A8C75 RS00700
gene id: 1821621:A8C75_RS00700
uniprot id: A0A1A9ETY5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1821621:A8C75 RS14060
gene id: 1821621:A8C75_RS14060
uniprot id: A0A1A9F067
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1821621:A8C75 RS14265
gene id: 1821621:A8C75_RS14265
uniprot id: A0A1A9F0Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1821621:A8C75 RS14955
gene id: 1821621:A8C75_RS14955
uniprot id: A0A1A9F0G0
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS09175
gene id: 1821621:A8C75_RS09175
uniprot id: A0A1A9EXL8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1821621:A8C75 RS05845
gene id: 1821621:A8C75_RS05845
uniprot id: A0A1A9EW73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS15375
gene id: 1821621:A8C75_RS15375
uniprot id: A0A1A9F1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1821621:A8C75 RS18420
gene id: 1821621:A8C75_RS18420
uniprot id: A0A1A9F3D9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1821621:A8C75 RS14410
gene id: 1821621:A8C75_RS14410
uniprot id: A0A1A9F024
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS21280
gene id: 1821621:A8C75_RS21280
uniprot id: A0A1A9F3H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS00855
gene id: 1821621:A8C75_RS00855
uniprot id: A0A1A9ETD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS01640
gene id: 1821621:A8C75_RS01640
uniprot id: A0A1A9EU75
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

1821621:A8C75 RS17095
gene id: 1821621:A8C75_RS17095
uniprot id: A0A1A9F1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS12345
gene id: 1821621:A8C75_RS12345
uniprot id: A0A1A9F0A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS03915
gene id: 1821621:A8C75_RS03915
uniprot id: A0A1A9EU81
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS22695
gene id: 1821621:A8C75_RS22695
uniprot id: A0A1A9F543
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1821621:A8C75 RS00800
gene id: 1821621:A8C75_RS00800
uniprot id: A0A1A9ETA9
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS13850
gene id: 1821621:A8C75_RS13850
uniprot id: A0A1A9EZW2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS02775
gene id: 1821621:A8C75_RS02775
uniprot id: A0A1A9EVC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1821621:A8C75 RS14670
gene id: 1821621:A8C75_RS14670
uniprot id: A0A1A9F1I5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1821621:A8C75 RS14690
gene id: 1821621:A8C75_RS14690
uniprot id: A0A1A9F0D0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1821621:A8C75 RS15150
gene id: 1821621:A8C75_RS15150
uniprot id: A0A1A9F0R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1821621:A8C75 RS21355
gene id: 1821621:A8C75_RS21355
uniprot id: A0A1A9F4J4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1821621:A8C75 RS02335
gene id: 1821621:A8C75_RS02335
uniprot id: A0A1A9EV35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1821621:A8C75 RS07485
gene id: 1821621:A8C75_RS07485
uniprot id: A0A1A9EWQ3
names: Similarity
messages: Belongs to the citrate synthase family.

1821621:A8C75 RS06140
gene id: 1821621:A8C75_RS06140
uniprot id: A0A1A9F5I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1821621:A8C75 RS09535
gene id: 1821621:A8C75_RS09535
uniprot id: A0A1A9EY81
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS07795
gene id: 1821621:A8C75_RS07795
uniprot id: A0A1A9EXC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1821621:A8C75 RS19235
gene id: 1821621:A8C75_RS19235
uniprot id: A0A1A9F2R7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS22170
gene id: 1821621:A8C75_RS22170
uniprot id: A0A1A9F412
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS20475
gene id: 1821621:A8C75_RS20475
uniprot id: A0A1A9F4H7
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1821621:A8C75 RS09385
gene id: 1821621:A8C75_RS09385
uniprot id: A0A1A9EYW4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1821621:A8C75 RS07565
gene id: 1821621:A8C75_RS07565
uniprot id: A0A1A9EXV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1821621:A8C75 RS11425
gene id: 1821621:A8C75_RS11425
uniprot id: A0A1A9F4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1821621:A8C75 RS01765
gene id: 1821621:A8C75_RS01765
uniprot id: A0A1A9ET25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1821621:A8C75 RS13445
gene id: 1821621:A8C75_RS13445
uniprot id: A0A1A9F0V5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1821621:A8C75 RS08110
gene id: 1821621:A8C75_RS08110
uniprot id: A0A1A9EWD3
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS05890
gene id: 1821621:A8C75_RS05890
uniprot id: A0A1A9EX02
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1821621:A8C75 RS03105
gene id: 1821621:A8C75_RS03105
uniprot id: A0A1A9EVA3
names: Similarity
messages: Belongs to the Gfa family.

1821621:A8C75 RS12000
gene id: 1821621:A8C75_RS12000
uniprot id: A0A1A9EZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS19390
gene id: 1821621:A8C75_RS19390
uniprot id: A0A1A9F2U6
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS07395
gene id: 1821621:A8C75_RS07395
uniprot id: A0A1A9EXD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS09125
gene id: 1821621:A8C75_RS09125
uniprot id: A0A1A9EYA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS04370
gene id: 1821621:A8C75_RS04370
uniprot id: A0A1A9EVC5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1821621:A8C75 RS13525
gene id: 1821621:A8C75_RS13525
uniprot id: A0A1A9EZL3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1821621:A8C75 RS10695
gene id: 1821621:A8C75_RS10695
uniprot id: A0A1A9EXN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS22370
gene id: 1821621:A8C75_RS22370
uniprot id: A0A1A9F5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1821621:A8C75 RS20245
gene id: 1821621:A8C75_RS20245
uniprot id: A0A1A9F401
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1821621:A8C75 RS13255
gene id: 1821621:A8C75_RS13255
uniprot id: A0A1A9F0B7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1821621:A8C75 RS17980
gene id: 1821621:A8C75_RS17980
uniprot id: A0A1A9F1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1821621:A8C75 RS13490
gene id: 1821621:A8C75_RS13490
uniprot id: A0A1A9F058
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1821621:A8C75 RS10905
gene id: 1821621:A8C75_RS10905
uniprot id: A0A1A9EZM1
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1821621:A8C75 RS00675
gene id: 1821621:A8C75_RS00675
uniprot id: A0A1A9EU92
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.
messages: Belongs to the rubredoxin family.

1821621:A8C75 RS01320
gene id: 1821621:A8C75_RS01320
uniprot id: A0A1A9EUB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

1821621:A8C75 RS12815
gene id: 1821621:A8C75_RS12815
uniprot id: A0A1A9EYS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1821621:A8C75 RS00525
gene id: 1821621:A8C75_RS00525
uniprot id: A0A1A9ET59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS04760
gene id: 1821621:A8C75_RS04760
uniprot id: A0A1A9EVT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS04550
gene id: 1821621:A8C75_RS04550
uniprot id: A0A1A9EWA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1821621:A8C75 RS00875
gene id: 1821621:A8C75_RS00875
uniprot id: A0A1A9EU19
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1821621:A8C75 RS17115
gene id: 1821621:A8C75_RS17115
uniprot id: A0A1A9F204
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1821621:A8C75 RS04905
gene id: 1821621:A8C75_RS04905
uniprot id: A0A1A9EW43
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1821621:A8C75 RS06910
gene id: 1821621:A8C75_RS06910
uniprot id: A0A1A9EWL4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1821621:A8C75 RS17425
gene id: 1821621:A8C75_RS17425
uniprot id: A0A1A9F2I6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1821621:A8C75 RS22280
gene id: 1821621:A8C75_RS22280
uniprot id: A0A1A9F3N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1821621:A8C75 RS17330
gene id: 1821621:A8C75_RS17330
uniprot id: A0A1A9F2R4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1821621:A8C75 RS05240
gene id: 1821621:A8C75_RS05240
uniprot id: A0A1A9EVS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1821621:A8C75 RS16485
gene id: 1821621:A8C75_RS16485
uniprot id: A0A1A9F5Z5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1821621:A8C75 RS01980
gene id: 1821621:A8C75_RS01980
uniprot id: A0A1A9EUN0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS02260
gene id: 1821621:A8C75_RS02260
uniprot id: A0A1A9EU21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS05790
gene id: 1821621:A8C75_RS05790
uniprot id: A0A1A9EWN8
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1821621:A8C75 RS05005
gene id: 1821621:A8C75_RS05005
uniprot id: A0A1A9EVI6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1821621:A8C75 RS07170
gene id: 1821621:A8C75_RS07170
uniprot id: A0A1A9EVV4
names: Similarity
messages: Belongs to the PhoH family.

1821621:A8C75 RS10820
gene id: 1821621:A8C75_RS10820
uniprot id: A0A1A9F628
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS22385
gene id: 1821621:A8C75_RS22385
uniprot id: A0A1A9F4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1821621:A8C75 RS02120
gene id: 1821621:A8C75_RS02120
uniprot id: A0A1A9EUP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1821621:A8C75 RS05385
gene id: 1821621:A8C75_RS05385
uniprot id: A0A1A9EUY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1821621:A8C75 RS04685
gene id: 1821621:A8C75_RS04685
uniprot id: A0A1A9EVC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1821621:A8C75 RS18545
gene id: 1821621:A8C75_RS18545
uniprot id: A0A1A9F331
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1821621:A8C75 RS17380
gene id: 1821621:A8C75_RS17380
uniprot id: A0A1A9F1L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1821621:A8C75 RS09670
gene id: 1821621:A8C75_RS09670
uniprot id: A0A1A9EZ12
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1821621:A8C75 RS21855
gene id: 1821621:A8C75_RS21855
uniprot id: A0A1A9F4T5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1821621:A8C75 RS13350
gene id: 1821621:A8C75_RS13350
uniprot id: A0A1A9F0Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1821621:A8C75 RS21465
gene id: 1821621:A8C75_RS21465
uniprot id: A0A1A9F3Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1821621:A8C75 RS01510
gene id: 1821621:A8C75_RS01510
uniprot id: A0A1A9ETT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1821621:A8C75 RS14845
gene id: 1821621:A8C75_RS14845
uniprot id: A0A1A9F0A2
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS02630
gene id: 1821621:A8C75_RS02630
uniprot id: A0A1A9F5D7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1821621:A8C75 RS07125
gene id: 1821621:A8C75_RS07125
uniprot id: A0A1A9EWJ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1821621:A8C75 RS10715
gene id: 1821621:A8C75_RS10715
uniprot id: A0A1A9EZ41
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1821621:A8C75 RS15145
gene id: 1821621:A8C75_RS15145
uniprot id: A0A1A9F1B6
names: Subcellular Location Annotation
messages: Cell inner membrane

1821621:A8C75 RS08210
gene id: 1821621:A8C75_RS08210
uniprot id: A0A1A9EY87
names: Similarity
messages: Belongs to the peptidase M18 family.

1821621:A8C75 RS10445
gene id: 1821621:A8C75_RS10445
uniprot id: A0A1A9EYP2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1821621:A8C75 RS09830
gene id: 1821621:A8C75_RS09830
uniprot id: A0A1A9EYN2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1821621:A8C75 RS00345
gene id: 1821621:A8C75_RS00345
uniprot id: A0A1A9EU25
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1821621:A8C75 RS07750
gene id: 1821621:A8C75_RS07750
uniprot id: A0A1A9EX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1821621:A8C75 RS04950
gene id: 1821621:A8C75_RS04950
uniprot id: A0A1A9EVH7
names: Similarity
messages: Belongs to the YciI family.

1821621:A8C75 RS09725
gene id: 1821621:A8C75_RS09725
uniprot id: A0A1A9EY36
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1821621:A8C75 RS16805
gene id: 1821621:A8C75_RS16805
uniprot id: A0A1A9F0T9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1821621:A8C75 RS00685
gene id: 1821621:A8C75_RS00685
uniprot id: A0A1A9ET96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1821621:A8C75 RS16115
gene id: 1821621:A8C75_RS16115
uniprot id: A0A1A9F5F5
names: Similarity
messages: Belongs to the PrpD family.

1821621:A8C75 RS20175
gene id: 1821621:A8C75_RS20175
uniprot id: A0A1A9F3V3
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).

1821621:A8C75 RS07220
gene id: 1821621:A8C75_RS07220
uniprot id: A0A1A9EXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1821621:A8C75 RS13080
gene id: 1821621:A8C75_RS13080
uniprot id: A0A1A9EZY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

1821621:A8C75 RS00770
gene id: 1821621:A8C75_RS00770
uniprot id: A0A1A9EU13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS03045
gene id: 1821621:A8C75_RS03045
uniprot id: A0A1A9EUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1821621:A8C75 RS10335
gene id: 1821621:A8C75_RS10335
uniprot id: A0A1A9EZ82
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1821621:A8C75 RS07505
gene id: 1821621:A8C75_RS07505
uniprot id: A0A1A9EX74
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1821621:A8C75 RS14330
gene id: 1821621:A8C75_RS14330
uniprot id: A0A1A9F0W9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1821621:A8C75 RS14860
gene id: 1821621:A8C75_RS14860
uniprot id: A0A1A9F1J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1821621:A8C75 RS21270
gene id: 1821621:A8C75_RS21270
uniprot id: A0A1A9F3K3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1821621:A8C75 RS20130
gene id: 1821621:A8C75_RS20130
uniprot id: A0A1A9F3K9
names: Similarity
messages: Belongs to the DSD1 family.

1821621:A8C75 RS21325
gene id: 1821621:A8C75_RS21325
uniprot id: A0A1A9F3L2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1821621:A8C75 RS16265
gene id: 1821621:A8C75_RS16265
uniprot id: A0A1A9F136
names: Similarity
messages: Belongs to the pyruvate kinase family.

1821621:A8C75 RS16720
gene id: 1821621:A8C75_RS16720
uniprot id: A0A1A9F239
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS02360
gene id: 1821621:A8C75_RS02360
uniprot id: A0A1A9EV59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS12625
gene id: 1821621:A8C75_RS12625
uniprot id: A0A1A9EZG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1821621:A8C75 RS05405
gene id: 1821621:A8C75_RS05405
uniprot id: A0A1A9F4W3
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1821621:A8C75 RS05105
gene id: 1821621:A8C75_RS05105
uniprot id: A0A1A9EVL0
names: Similarity
messages: Belongs to the elongation factor P family.

1821621:A8C75 RS21425
gene id: 1821621:A8C75_RS21425
uniprot id: A0A1A9F3N2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1821621:A8C75 RS07670
gene id: 1821621:A8C75_RS07670
uniprot id: A0A1A9EXI6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1821621:A8C75 RS19000
gene id: 1821621:A8C75_RS19000
uniprot id: A0A1A9F2G6
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1821621:A8C75 RS00405
gene id: 1821621:A8C75_RS00405
uniprot id: A0A1A9ESA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1821621:A8C75 RS18130
gene id: 1821621:A8C75_RS18130
uniprot id: A0A1A9F2I0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1821621:A8C75 RS17185
gene id: 1821621:A8C75_RS17185
uniprot id: A0A1A9F2S3
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1821621:A8C75 RS03630
gene id: 1821621:A8C75_RS03630
uniprot id: A0A1A9EVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1821621:A8C75 RS03690
gene id: 1821621:A8C75_RS03690
uniprot id: A0A1A9EVT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS18975
gene id: 1821621:A8C75_RS18975
uniprot id: A0A1A9F2Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS05670
gene id: 1821621:A8C75_RS05670
uniprot id: A0A1A9EW09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS06935
gene id: 1821621:A8C75_RS06935
uniprot id: A0A1A9EWR5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS05415
gene id: 1821621:A8C75_RS05415
uniprot id: A0A1A9EWR3
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1821621:A8C75 RS03745
gene id: 1821621:A8C75_RS03745
uniprot id: A0A1A9EV86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS09860
gene id: 1821621:A8C75_RS09860
uniprot id: A0A1A9EX81
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1821621:A8C75 RS09710
gene id: 1821621:A8C75_RS09710
uniprot id: A0A1A9EYA7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1821621:A8C75 RS20920
gene id: 1821621:A8C75_RS20920
uniprot id: A0A1A9F3N3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS21340
gene id: 1821621:A8C75_RS21340
uniprot id: A0A1A9F4E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1821621:A8C75 RS17310
gene id: 1821621:A8C75_RS17310
uniprot id: A0A1A9F1L8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1821621:A8C75 RS07065
gene id: 1821621:A8C75_RS07065
uniprot id: A0A1A9EWM2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS21360
gene id: 1821621:A8C75_RS21360
uniprot id: A0A1A9F3W4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1821621:A8C75 RS22740
gene id: 1821621:A8C75_RS22740
uniprot id: A0A1A9F688
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1821621:A8C75 RS11680
gene id: 1821621:A8C75_RS11680
uniprot id: A0A1A9EYU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1821621:A8C75 RS01100
gene id: 1821621:A8C75_RS01100
uniprot id: A0A1A9ETX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1821621:A8C75 RS15780
gene id: 1821621:A8C75_RS15780
uniprot id: A0A1A9F1N4
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

1821621:A8C75 RS04925
gene id: 1821621:A8C75_RS04925
uniprot id: A0A1A9EVW9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1821621:A8C75 RS16050
gene id: 1821621:A8C75_RS16050
uniprot id: A0A1A9F104
names: Similarity
messages: Belongs to the pirin family.

1821621:A8C75 RS07920
gene id: 1821621:A8C75_RS07920
uniprot id: A0A1A9EX78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS04380
gene id: 1821621:A8C75_RS04380
uniprot id: A0A1A9EW65
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1821621:A8C75 RS03835
gene id: 1821621:A8C75_RS03835
uniprot id: A0A1A9EVJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS20375
gene id: 1821621:A8C75_RS20375
uniprot id: A0A1A9F660
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS01615
gene id: 1821621:A8C75_RS01615
uniprot id: A0A1A9ETQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1821621:A8C75 RS07465
gene id: 1821621:A8C75_RS07465
uniprot id: A0A1A9EWZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1821621:A8C75 RS20995
gene id: 1821621:A8C75_RS20995
uniprot id: A0A1A9F3F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1821621:A8C75 RS08025
gene id: 1821621:A8C75_RS08025
uniprot id: A0A1A9EY39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1821621:A8C75 RS07475
gene id: 1821621:A8C75_RS07475
uniprot id: A0A1A9EW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1821621:A8C75 RS21035
gene id: 1821621:A8C75_RS21035
uniprot id: A0A1A9F3Q0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1821621:A8C75 RS02575
gene id: 1821621:A8C75_RS02575
uniprot id: A0A1A9EVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1821621:A8C75 RS15295
gene id: 1821621:A8C75_RS15295
uniprot id: A0A1A9F1G1
names: Similarity
messages: Belongs to the SUI1 family.

1821621:A8C75 RS00690
gene id: 1821621:A8C75_RS00690
uniprot id: A0A1A9ET88
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1821621:A8C75 RS22240
gene id: 1821621:A8C75_RS22240
uniprot id: A0A1A9F5P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1821621:A8C75 RS17135
gene id: 1821621:A8C75_RS17135
uniprot id: A0A1A9F2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1821621:A8C75 RS19650
gene id: 1821621:A8C75_RS19650
uniprot id: A0A1A9F2M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS07850
gene id: 1821621:A8C75_RS07850
uniprot id: A0A1A9EXE2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1821621:A8C75 RS12590
gene id: 1821621:A8C75_RS12590
uniprot id: A0A1A9EZB9
names: Similarity
messages: Belongs to the AHA1 family.

1821621:A8C75 RS22300
gene id: 1821621:A8C75_RS22300
uniprot id: A0A1A9F4X4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS05000
gene id: 1821621:A8C75_RS05000
uniprot id: A0A1A9EUR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS17495
gene id: 1821621:A8C75_RS17495
uniprot id: A0A1A9F1P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1821621:A8C75 RS14465
gene id: 1821621:A8C75_RS14465
uniprot id: A0A1A9F033
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1821621:A8C75 RS12325
gene id: 1821621:A8C75_RS12325
uniprot id: A0A1A9F077
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1821621:A8C75 RS17120
gene id: 1821621:A8C75_RS17120
uniprot id: A0A1A9F5H6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS07240
gene id: 1821621:A8C75_RS07240
uniprot id: A0A1A9EWS7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1821621:A8C75 RS03975
gene id: 1821621:A8C75_RS03975
uniprot id: A0A1A9EUX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1821621:A8C75 RS06195
gene id: 1821621:A8C75_RS06195
uniprot id: A0A1A9EWD0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1821621:A8C75 RS07825
gene id: 1821621:A8C75_RS07825
uniprot id: A0A1A9EX08
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1821621:A8C75 RS09240
gene id: 1821621:A8C75_RS09240
uniprot id: A0A1A9EXP6
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1821621:A8C75 RS10825
gene id: 1821621:A8C75_RS10825
uniprot id: A0A1A9EZH0
names: Similarity
messages: Belongs to the RutC family.

1821621:A8C75 RS01810
gene id: 1821621:A8C75_RS01810
uniprot id: A0A1A9EUJ9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1821621:A8C75 RS09355
gene id: 1821621:A8C75_RS09355
uniprot id: A0A1A9EXR6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1821621:A8C75 RS20070
gene id: 1821621:A8C75_RS20070
uniprot id: A0A1A9F453
names: Similarity
messages: Belongs to the GSP E family.

1821621:A8C75 RS12925
gene id: 1821621:A8C75_RS12925
uniprot id: A0A1A9EYU7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS03515
gene id: 1821621:A8C75_RS03515
uniprot id: A0A1A9EV15
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1821621:A8C75 RS08815
gene id: 1821621:A8C75_RS08815
uniprot id: A0A1A9EYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1821621:A8C75 RS07840
gene id: 1821621:A8C75_RS07840
uniprot id: A0A1A9EXL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1821621:A8C75 RS22475
gene id: 1821621:A8C75_RS22475
uniprot id: A0A1A9F4R1
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1821621:A8C75 RS00400
gene id: 1821621:A8C75_RS00400
uniprot id: A0A1A9EU34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1821621:A8C75 RS22810
gene id: 1821621:A8C75_RS22810
uniprot id: A0A1A9F4X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1821621:A8C75 RS09930
gene id: 1821621:A8C75_RS09930
uniprot id: A0A1A9EXW7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS03405
gene id: 1821621:A8C75_RS03405
uniprot id: A0A1A9EUP1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS06370
gene id: 1821621:A8C75_RS06370
uniprot id: A0A1A9EWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1821621:A8C75 RS01630
gene id: 1821621:A8C75_RS01630
uniprot id: A0A1A9EUF1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1821621:A8C75 RS10550
gene id: 1821621:A8C75_RS10550
uniprot id: A0A1A9EZ08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS08870
gene id: 1821621:A8C75_RS08870
uniprot id: A0A1A9EYL9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1821621:A8C75 RS02185
gene id: 1821621:A8C75_RS02185
uniprot id: A0A1A9EUS9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1821621:A8C75 RS01645
gene id: 1821621:A8C75_RS01645
uniprot id: A0A1A9EUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1821621:A8C75 RS19680
gene id: 1821621:A8C75_RS19680
uniprot id: A0A1A9F2Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS06785
gene id: 1821621:A8C75_RS06785
uniprot id: A0A1A9EWD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1821621:A8C75 RS17880
gene id: 1821621:A8C75_RS17880
uniprot id: A0A1A9F1W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS15715
gene id: 1821621:A8C75_RS15715
uniprot id: A0A1A9F0V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS17125
gene id: 1821621:A8C75_RS17125
uniprot id: A0A1A9F2D4
names: Similarity
messages: Belongs to the universal stress protein A family.

1821621:A8C75 RS11295
gene id: 1821621:A8C75_RS11295
uniprot id: A0A1A9EYN6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1821621:A8C75 RS10590
gene id: 1821621:A8C75_RS10590
uniprot id: A0A1A9EYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1821621:A8C75 RS16475
gene id: 1821621:A8C75_RS16475
uniprot id: A0A1A9F2F0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1821621:A8C75 RS07915
gene id: 1821621:A8C75_RS07915
uniprot id: A0A1A9F5L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS02885
gene id: 1821621:A8C75_RS02885
uniprot id: A0A1A9EUW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1821621:A8C75 RS00470
gene id: 1821621:A8C75_RS00470
uniprot id: A0A1A9ET49
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1821621:A8C75 RS08475
gene id: 1821621:A8C75_RS08475
uniprot id: A0A1A9EYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1821621:A8C75 RS06240
gene id: 1821621:A8C75_RS06240
uniprot id: A0A1A9EWK5
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1821621:A8C75 RS15000
gene id: 1821621:A8C75_RS15000
uniprot id: A0A1A9F1Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1821621:A8C75 RS21490
gene id: 1821621:A8C75_RS21490
uniprot id: A0A1A9F3L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1821621:A8C75 RS08805
gene id: 1821621:A8C75_RS08805
uniprot id: A0A1A9EY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1821621:A8C75 RS01165
gene id: 1821621:A8C75_RS01165
uniprot id: A0A1A9EUI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS09300
gene id: 1821621:A8C75_RS09300
uniprot id: A0A1A9EYD0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS21335
gene id: 1821621:A8C75_RS21335
uniprot id: A0A1A9F3I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1821621:A8C75 RS14875
gene id: 1821621:A8C75_RS14875
uniprot id: A0A1A9F0V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS02350
gene id: 1821621:A8C75_RS02350
uniprot id: A0A1A9EUG6
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1821621:A8C75 RS09565
gene id: 1821621:A8C75_RS09565
uniprot id: A0A1A9F4M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1821621:A8C75 RS19090
gene id: 1821621:A8C75_RS19090
uniprot id: A0A1A9F5V4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1821621:A8C75 RS05085
gene id: 1821621:A8C75_RS05085
uniprot id: A0A1A9EWA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1821621:A8C75 RS05720
gene id: 1821621:A8C75_RS05720
uniprot id: A0A1A9EW19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1821621:A8C75 RS01335
gene id: 1821621:A8C75_RS01335
uniprot id: A0A1A9EST9
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1821621:A8C75 RS04170
gene id: 1821621:A8C75_RS04170
uniprot id: A0A1A9EVH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

1821621:A8C75 RS07150
gene id: 1821621:A8C75_RS07150
uniprot id: A0A1A9EX20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1821621:A8C75 RS16090
gene id: 1821621:A8C75_RS16090
uniprot id: A0A1A9F281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS15710
gene id: 1821621:A8C75_RS15710
uniprot id: A0A1A9F0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Cell inner membrane

1821621:A8C75 RS18480
gene id: 1821621:A8C75_RS18480
uniprot id: A0A1A9F277
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1821621:A8C75 RS04035
gene id: 1821621:A8C75_RS04035
uniprot id: A0A1A9EUZ2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1821621:A8C75 RS17060
gene id: 1821621:A8C75_RS17060
uniprot id: A0A1A9F1Z2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS01200
gene id: 1821621:A8C75_RS01200
uniprot id: A0A1A9EUG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1821621:A8C75 RS22375
gene id: 1821621:A8C75_RS22375
uniprot id: A0A1A9F4P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS19175
gene id: 1821621:A8C75_RS19175
uniprot id: A0A1A9F3E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1821621:A8C75 RS11800
gene id: 1821621:A8C75_RS11800
uniprot id: A0A1A9EYW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS22325
gene id: 1821621:A8C75_RS22325
uniprot id: A0A1A9F5D6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1821621:A8C75 RS10070
gene id: 1821621:A8C75_RS10070
uniprot id: A0A1A9EY90
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1821621:A8C75 RS17995
gene id: 1821621:A8C75_RS17995
uniprot id: A0A1A9F1X6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS07495
gene id: 1821621:A8C75_RS07495
uniprot id: A0A1A9EXF3
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1821621:A8C75 RS12100
gene id: 1821621:A8C75_RS12100
uniprot id: A0A1A9F040
names: Similarity
messages: Belongs to the peptidase M16 family.

1821621:A8C75 RS21705
gene id: 1821621:A8C75_RS21705
uniprot id: A0A1A9F4Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1821621:A8C75 RS13690
gene id: 1821621:A8C75_RS13690
uniprot id: A0A1A9EZP2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1821621:A8C75 RS18355
gene id: 1821621:A8C75_RS18355
uniprot id: A0A1A9F2M6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1821621:A8C75 RS00640
gene id: 1821621:A8C75_RS00640
uniprot id: A0A1A9ETB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1821621:A8C75 RS04895
gene id: 1821621:A8C75_RS04895
uniprot id: A0A1A9EVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1821621:A8C75 RS05255
gene id: 1821621:A8C75_RS05255
uniprot id: A0A1A9EW27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS11870
gene id: 1821621:A8C75_RS11870
uniprot id: A0A1A9EZN0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1821621:A8C75 RS14230
gene id: 1821621:A8C75_RS14230
uniprot id: A0A1A9F1A7
names: Similarity
messages: Belongs to the GcvT family.

1821621:A8C75 RS22360
gene id: 1821621:A8C75_RS22360
uniprot id: A0A1A9F400
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1821621:A8C75 RS22415
gene id: 1821621:A8C75_RS22415
uniprot id: A0A1A9F4Z4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1821621:A8C75 RS12725
gene id: 1821621:A8C75_RS12725
uniprot id: A0A1A9F5A0
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1821621:A8C75 RS05910
gene id: 1821621:A8C75_RS05910
uniprot id: A0A1A9EW83
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1821621:A8C75 RS12305
gene id: 1821621:A8C75_RS12305
uniprot id: A0A1A9EZ47
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1821621:A8C75 RS05595
gene id: 1821621:A8C75_RS05595
uniprot id: A0A1A9EWV7
names: Similarity
messages: Belongs to the SlyX family.

1821621:A8C75 RS04440
gene id: 1821621:A8C75_RS04440
uniprot id: A0A1A9EVM1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS04240
gene id: 1821621:A8C75_RS04240
uniprot id: A0A1A9EW61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1821621:A8C75 RS10870
gene id: 1821621:A8C75_RS10870
uniprot id: A0A1A9EYC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS01770
gene id: 1821621:A8C75_RS01770
uniprot id: A0A1A9ETV5
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS06115
gene id: 1821621:A8C75_RS06115
uniprot id: A0A1A9EWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1821621:A8C75 RS19575
gene id: 1821621:A8C75_RS19575
uniprot id: A0A1A9F2Q9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS15995
gene id: 1821621:A8C75_RS15995
uniprot id: A0A1A9EWH6
names: Similarity
messages: Belongs to the transposase 8 family.

1821621:A8C75 RS22775
gene id: 1821621:A8C75_RS22775
uniprot id: A0A1A9F5L3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1821621:A8C75 RS15205
gene id: 1821621:A8C75_RS15205
uniprot id: A0A1A9F0S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1821621:A8C75 RS13395
gene id: 1821621:A8C75_RS13395
uniprot id: A0A1A9EZ36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1821621:A8C75 RS21385
gene id: 1821621:A8C75_RS21385
uniprot id: A0A1A9F3J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1821621:A8C75 RS01400
gene id: 1821621:A8C75_RS01400
uniprot id: A0A1A9ETR3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1821621:A8C75 RS04215
gene id: 1821621:A8C75_RS04215
uniprot id: A0A1A9EVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1821621:A8C75 RS13295
gene id: 1821621:A8C75_RS13295
uniprot id: A0A1A9F0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS05800
gene id: 1821621:A8C75_RS05800
uniprot id: A0A1A9EWZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

1821621:A8C75 RS20990
gene id: 1821621:A8C75_RS20990
uniprot id: A0A1A9F585
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1821621:A8C75 RS16715
gene id: 1821621:A8C75_RS16715
uniprot id: A0A1A9F1B0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS20565
gene id: 1821621:A8C75_RS20565
uniprot id: A0A1A9F3S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1821621:A8C75 RS12165
gene id: 1821621:A8C75_RS12165
uniprot id: A0A1A9EZR5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1821621:A8C75 RS17600
gene id: 1821621:A8C75_RS17600
uniprot id: A0A1A9F188
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS13455
gene id: 1821621:A8C75_RS13455
uniprot id: A0A1A9EZ51
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS04500
gene id: 1821621:A8C75_RS04500
uniprot id: A0A1A9EW89
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1821621:A8C75 RS14215
gene id: 1821621:A8C75_RS14215
uniprot id: A0A1A9F0I9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1821621:A8C75 RS18370
gene id: 1821621:A8C75_RS18370
uniprot id: A0A1A9F3C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

1821621:A8C75 RS05570
gene id: 1821621:A8C75_RS05570
uniprot id: A0A1A9EWG7
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1821621:A8C75 RS04915
gene id: 1821621:A8C75_RS04915
uniprot id: A0A1A9EWG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1821621:A8C75 RS02980
gene id: 1821621:A8C75_RS02980
uniprot id: A0A1A9EV57
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1821621:A8C75 RS21725
gene id: 1821621:A8C75_RS21725
uniprot id: A0A1A9F3S8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS20710
gene id: 1821621:A8C75_RS20710
uniprot id: A0A1A9F380
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS04700
gene id: 1821621:A8C75_RS04700
uniprot id: A0A1A9EWD2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1821621:A8C75 RS22470
gene id: 1821621:A8C75_RS22470
uniprot id: A0A1A9F5D0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1821621:A8C75 RS09990
gene id: 1821621:A8C75_RS09990
uniprot id: A0A1A9EYR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS19370
gene id: 1821621:A8C75_RS19370
uniprot id: A0A1A9F3F6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1821621:A8C75 RS22450
gene id: 1821621:A8C75_RS22450
uniprot id: A0A1A9F458
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1821621:A8C75 RS11460
gene id: 1821621:A8C75_RS11460
uniprot id: A0A1A9EYK3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1821621:A8C75 RS22430
gene id: 1821621:A8C75_RS22430
uniprot id: A0A1A9F537
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1821621:A8C75 RS01420
gene id: 1821621:A8C75_RS01420
uniprot id: A0A1A9EU39
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1821621:A8C75 RS16255
gene id: 1821621:A8C75_RS16255
uniprot id: A0A1A9F2B4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1821621:A8C75 RS23895
gene id: 1821621:A8C75_RS23895
uniprot id: A0A1A9EVB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1821621:A8C75 RS18945
gene id: 1821621:A8C75_RS18945
uniprot id: A0A1A9F2F6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1821621:A8C75 RS06185
gene id: 1821621:A8C75_RS06185
uniprot id: A0A1A9EWJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1821621:A8C75 RS05990
gene id: 1821621:A8C75_RS05990
uniprot id: A0A1A9EWP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1821621:A8C75 RS19125
gene id: 1821621:A8C75_RS19125
uniprot id: A0A1A9F2I4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1821621:A8C75 RS01675
gene id: 1821621:A8C75_RS01675
uniprot id: A0A1A9ETW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1821621:A8C75 RS20940
gene id: 1821621:A8C75_RS20940
uniprot id: A0A1A9F392
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1821621:A8C75 RS14205
gene id: 1821621:A8C75_RS14205
uniprot id: A0A1A9F0W4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1821621:A8C75 RS03865
gene id: 1821621:A8C75_RS03865
uniprot id: A0A1A9EU72
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1821621:A8C75 RS08500
gene id: 1821621:A8C75_RS08500
uniprot id: A0A1A9EWK9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1821621:A8C75 RS14620
gene id: 1821621:A8C75_RS14620
uniprot id: A0A1A9F063
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1821621:A8C75 RS06775
gene id: 1821621:A8C75_RS06775
uniprot id: A0A1A9EVN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1821621:A8C75 RS22220
gene id: 1821621:A8C75_RS22220
uniprot id: A0A1A9F416
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1821621:A8C75 RS13765
gene id: 1821621:A8C75_RS13765
uniprot id: A0A1A9F0A6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1821621:A8C75 RS09810
gene id: 1821621:A8C75_RS09810
uniprot id: A0A1A9EXX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1821621:A8C75 RS00520
gene id: 1821621:A8C75_RS00520
uniprot id: A0A1A9ET64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1821621:A8C75 RS10875
gene id: 1821621:A8C75_RS10875
uniprot id: A0A1A9EYH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS01040
gene id: 1821621:A8C75_RS01040
uniprot id: A0A1A9EUD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS15050
gene id: 1821621:A8C75_RS15050
uniprot id: A0A1A9F1R3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1821621:A8C75 RS10115
gene id: 1821621:A8C75_RS10115
uniprot id: A0A1A9EYS7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS12510
gene id: 1821621:A8C75_RS12510
uniprot id: A0A1A9EYL2
names: Similarity
messages: Belongs to the GST superfamily.

1821621:A8C75 RS14630
gene id: 1821621:A8C75_RS14630
uniprot id: A0A1A9F0C0
names: Similarity
messages: Belongs to the citrate synthase family.

1821621:A8C75 RS21930
gene id: 1821621:A8C75_RS21930
uniprot id: A0A1A9F3X1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS05295
gene id: 1821621:A8C75_RS05295
uniprot id: A0A1A9EVU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1821621:A8C75 RS14350
gene id: 1821621:A8C75_RS14350
uniprot id: A0A1A9F054
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1821621:A8C75 RS21570
gene id: 1821621:A8C75_RS21570
uniprot id: A0A1A9F4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1821621:A8C75 RS02480
gene id: 1821621:A8C75_RS02480
uniprot id: A0A1A9EUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1821621:A8C75 RS01365
gene id: 1821621:A8C75_RS01365
uniprot id: A0A1A9EU29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1821621:A8C75 RS22735
gene id: 1821621:A8C75_RS22735
uniprot id: A0A1A9F466
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1821621:A8C75 RS20280
gene id: 1821621:A8C75_RS20280
uniprot id: A0A1A9F3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1821621:A8C75 RS17900
gene id: 1821621:A8C75_RS17900
uniprot id: A0A1A9F2P7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1821621:A8C75 RS21805
gene id: 1821621:A8C75_RS21805
uniprot id: A0A1A9F4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS03490
gene id: 1821621:A8C75_RS03490
uniprot id: A0A1A9EUV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1821621:A8C75 RS22180
gene id: 1821621:A8C75_RS22180
uniprot id: A0A1A9F3X2
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1821621:A8C75 RS19010
gene id: 1821621:A8C75_RS19010
uniprot id: A0A1A9F2E2
names: Similarity
messages: Belongs to the UxaA family.

1821621:A8C75 RS14590
gene id: 1821621:A8C75_RS14590
uniprot id: A0A1A9F119
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1821621:A8C75 RS05310
gene id: 1821621:A8C75_RS05310
uniprot id: A0A1A9EW36
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1821621:A8C75 RS14200
gene id: 1821621:A8C75_RS14200
uniprot id: A0A1A9F039
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1821621:A8C75 RS06945
gene id: 1821621:A8C75_RS06945
uniprot id: A0A1A9EVR1
names: Similarity
messages: Belongs to the HIBADH-related family.

1821621:A8C75 RS12780
gene id: 1821621:A8C75_RS12780
uniprot id: A0A1A9EZE6
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS05050
gene id: 1821621:A8C75_RS05050
uniprot id: A0A1A9EUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS05530
gene id: 1821621:A8C75_RS05530
uniprot id: A0A1A9EW79
names: Similarity
messages: Belongs to the UPF0502 family.

1821621:A8C75 RS07085
gene id: 1821621:A8C75_RS07085
uniprot id: A0A1A9EX85
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS18875
gene id: 1821621:A8C75_RS18875
uniprot id: A0A1A9F3L9
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS07950
gene id: 1821621:A8C75_RS07950
uniprot id: A0A1A9EX42
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1821621:A8C75 RS05820
gene id: 1821621:A8C75_RS05820
uniprot id: A0A1A9EW37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1821621:A8C75 RS07490
gene id: 1821621:A8C75_RS07490
uniprot id: A0A1A9EWW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1821621:A8C75 RS22250
gene id: 1821621:A8C75_RS22250
uniprot id: A0A1A9F4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1821621:A8C75 RS21445
gene id: 1821621:A8C75_RS21445
uniprot id: A0A1A9F4V8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1821621:A8C75 RS12070
gene id: 1821621:A8C75_RS12070
uniprot id: A0A1A9EYC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1821621:A8C75 RS12130
gene id: 1821621:A8C75_RS12130
uniprot id: A0A1A9EZ18
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1821621:A8C75 RS09790
gene id: 1821621:A8C75_RS09790
uniprot id: A0A1A9EZ33
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS14080
gene id: 1821621:A8C75_RS14080
uniprot id: A0A1A9EZZ9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1821621:A8C75 RS02140
gene id: 1821621:A8C75_RS02140
uniprot id: A0A1A9EUC8
names: Similarity
messages: Belongs to the MotB family.

1821621:A8C75 RS10655
gene id: 1821621:A8C75_RS10655
uniprot id: A0A1A9EZ31
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1821621:A8C75 RS04480
gene id: 1821621:A8C75_RS04480
uniprot id: A0A1A9EV87
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1821621:A8C75 RS21430
gene id: 1821621:A8C75_RS21430
uniprot id: A0A1A9F3I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1821621:A8C75 RS10545
gene id: 1821621:A8C75_RS10545
uniprot id: A0A1A9EYB9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1821621:A8C75 RS01705
gene id: 1821621:A8C75_RS01705
uniprot id: A0A1A9EUU1
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS21365
gene id: 1821621:A8C75_RS21365
uniprot id: A0A1A9F4X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1821621:A8C75 RS10110
gene id: 1821621:A8C75_RS10110
uniprot id: A0A1A9EYH6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1821621:A8C75 RS12845
gene id: 1821621:A8C75_RS12845
uniprot id: A0A1A9F0G6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS11655
gene id: 1821621:A8C75_RS11655
uniprot id: A0A1A9EZH1
names: Similarity
messages: Belongs to the HsdR family.

1821621:A8C75 RS10510
gene id: 1821621:A8C75_RS10510
uniprot id: A0A1A9EYQ0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1821621:A8C75 RS05840
gene id: 1821621:A8C75_RS05840
uniprot id: A0A1A9EWP8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1821621:A8C75 RS15895
gene id: 1821621:A8C75_RS15895
uniprot id: A0A1A9F1D5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1821621:A8C75 RS11820
gene id: 1821621:A8C75_RS11820
uniprot id: A0A1A9EZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1821621:A8C75 RS12905
gene id: 1821621:A8C75_RS12905
uniprot id: A0A1A9EZV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1821621:A8C75 RS00340
gene id: 1821621:A8C75_RS00340
uniprot id: A0A1A9ETF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS18175
gene id: 1821621:A8C75_RS18175
uniprot id: A0A1A9F2U3
names: Similarity
messages: Belongs to the peptidase C56 family.

1821621:A8C75 RS20935
gene id: 1821621:A8C75_RS20935
uniprot id: A0A1A9F3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1821621:A8C75 RS00745
gene id: 1821621:A8C75_RS00745
uniprot id: A0A1A9ETE0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1821621:A8C75 RS14695
gene id: 1821621:A8C75_RS14695
uniprot id: A0A1A9F151
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1821621:A8C75 RS20150
gene id: 1821621:A8C75_RS20150
uniprot id: A0A1A9F2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1821621:A8C75 RS07755
gene id: 1821621:A8C75_RS07755
uniprot id: A0A1A9EY01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1821621:A8C75 RS21095
gene id: 1821621:A8C75_RS21095
uniprot id: A0A1A9F4T0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1821621:A8C75 RS20600
gene id: 1821621:A8C75_RS20600
uniprot id: A0A1A9F361
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1821621:A8C75 RS17435
gene id: 1821621:A8C75_RS17435
uniprot id: A0A1A9F2W3
names: Similarity
messages: Belongs to the YfgM family.

1821621:A8C75 RS21435
gene id: 1821621:A8C75_RS21435
uniprot id: A0A1A9F3K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1821621:A8C75 RS02470
gene id: 1821621:A8C75_RS02470
uniprot id: A0A1A9EU83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1821621:A8C75 RS22800
gene id: 1821621:A8C75_RS22800
uniprot id: A0A1A9F562
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS01355
gene id: 1821621:A8C75_RS01355
uniprot id: A0A1A9EUA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1821621:A8C75 RS21230
gene id: 1821621:A8C75_RS21230
uniprot id: A0A1A9F4R8
names: Similarity
messages: Belongs to the hyi family.

1821621:A8C75 RS20030
gene id: 1821621:A8C75_RS20030
uniprot id: A0A1A9F3V7
names: Similarity
messages: Belongs to the UPF0231 family.

1821621:A8C75 RS03790
gene id: 1821621:A8C75_RS03790
uniprot id: A0A1A9EVV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS17990
gene id: 1821621:A8C75_RS17990
uniprot id: A0A1A9F1S4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1821621:A8C75 RS17820
gene id: 1821621:A8C75_RS17820
uniprot id: A0A1A9F1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1821621:A8C75 RS22085
gene id: 1821621:A8C75_RS22085
uniprot id: A0A1A9F5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1821621:A8C75 RS20440
gene id: 1821621:A8C75_RS20440
uniprot id: A0A1A9F336
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1821621:A8C75 RS02080
gene id: 1821621:A8C75_RS02080
uniprot id: A0A1A9EUQ2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1821621:A8C75 RS10450
gene id: 1821621:A8C75_RS10450
uniprot id: A0A1A9EYY2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS20260
gene id: 1821621:A8C75_RS20260
uniprot id: A0A1A9F2P0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1821621:A8C75 RS00050
gene id: 1821621:A8C75_RS00050
uniprot id: A0A1A9ETW9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1821621:A8C75 RS21555
gene id: 1821621:A8C75_RS21555
uniprot id: A0A1A9F3Q3
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1821621:A8C75 RS03270
gene id: 1821621:A8C75_RS03270
uniprot id: A0A1A9EVD1
names: Similarity
messages: Belongs to the creatininase superfamily.

1821621:A8C75 RS05175
gene id: 1821621:A8C75_RS05175
uniprot id: A0A1A9EVR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1821621:A8C75 RS18765
gene id: 1821621:A8C75_RS18765
uniprot id: A0A1A9F1U9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS17660
gene id: 1821621:A8C75_RS17660
uniprot id: A0A1A9F1L7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS11205
gene id: 1821621:A8C75_RS11205
uniprot id: A0A1A9EYS8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1821621:A8C75 RS17525
gene id: 1821621:A8C75_RS17525
uniprot id: A0A1A9F2K6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1821621:A8C75 RS21440
gene id: 1821621:A8C75_RS21440
uniprot id: A0A1A9F4H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1821621:A8C75 RS02930
gene id: 1821621:A8C75_RS02930
uniprot id: A0A1A9EVG9
names: Similarity
messages: Belongs to the Skp family.

1821621:A8C75 RS00580
gene id: 1821621:A8C75_RS00580
uniprot id: A0A1A9ET69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1821621:A8C75 RS07780
gene id: 1821621:A8C75_RS07780
uniprot id: A0A1A9EX19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1821621:A8C75 RS11560
gene id: 1821621:A8C75_RS11560
uniprot id: A0A1A9EYS5
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1821621:A8C75 RS20930
gene id: 1821621:A8C75_RS20930
uniprot id: A0A1A9F306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS05245
gene id: 1821621:A8C75_RS05245
uniprot id: A0A1A9EWA4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1821621:A8C75 RS13895
gene id: 1821621:A8C75_RS13895
uniprot id: A0A1A9EZD9
names: Subcellular Location Annotation
messages: Cell inner membrane

1821621:A8C75 RS16935
gene id: 1821621:A8C75_RS16935
uniprot id: A0A1A9F609
names: Similarity
messages: Belongs to the UPF0246 family.

1821621:A8C75 RS21345
gene id: 1821621:A8C75_RS21345
uniprot id: A0A1A9F4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1821621:A8C75 RS20455
gene id: 1821621:A8C75_RS20455
uniprot id: A0A1A9F6K1
names: Similarity
messages: Belongs to the Gfa family.

1821621:A8C75 RS09640
gene id: 1821621:A8C75_RS09640
uniprot id: A0A1A9EYI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1821621:A8C75 RS14250
gene id: 1821621:A8C75_RS14250
uniprot id: A0A1A9EZZ4
names: Similarity
messages: Belongs to the peptidase S11 family.

1821621:A8C75 RS20165
gene id: 1821621:A8C75_RS20165
uniprot id: A0A1A9F2Y9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1821621:A8C75 RS11785
gene id: 1821621:A8C75_RS11785
uniprot id: A0A1A9F006
names: Similarity
messages: Belongs to the pyruvate kinase family.

1821621:A8C75 RS11775
gene id: 1821621:A8C75_RS11775
uniprot id: A0A1A9EZJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1821621:A8C75 RS12455
gene id: 1821621:A8C75_RS12455
uniprot id: A0A1A9EYJ1
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1821621:A8C75 RS01710
gene id: 1821621:A8C75_RS01710
uniprot id: A0A1A9ET14
names: Similarity
messages: Belongs to the glutamine synthetase family.

1821621:A8C75 RS13440
gene id: 1821621:A8C75_RS13440
uniprot id: A0A1A9EZW0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1821621:A8C75 RS07420
gene id: 1821621:A8C75_RS07420
uniprot id: A0A1A9EXT8
names: Similarity
messages: Belongs to the peptidase M1 family.

1821621:A8C75 RS13420
gene id: 1821621:A8C75_RS13420
uniprot id: A0A1A9F0R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1821621:A8C75 RS02690
gene id: 1821621:A8C75_RS02690
uniprot id: A0A1A9EVC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1821621:A8C75 RS18845
gene id: 1821621:A8C75_RS18845
uniprot id: A0A1A9F2B1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1821621:A8C75 RS14775
gene id: 1821621:A8C75_RS14775
uniprot id: A0A1A9F0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1821621:A8C75 RS16800
gene id: 1821621:A8C75_RS16800
uniprot id: A0A1A9F2K0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1821621:A8C75 RS12800
gene id: 1821621:A8C75_RS12800
uniprot id: A0A1A9F031
names: Subcellular Location Annotation
messages: Membrane

1821621:A8C75 RS09285
gene id: 1821621:A8C75_RS09285
uniprot id: A0A1A9EXN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1821621:A8C75 RS08010
gene id: 1821621:A8C75_RS08010
uniprot id: A0A1A9EWZ3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1821621:A8C75 RS04565
gene id: 1821621:A8C75_RS04565
uniprot id: A0A1A9EVI8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1821621:A8C75 RS04190
gene id: 1821621:A8C75_RS04190
uniprot id: A0A1A9EUC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1821621:A8C75 RS02055
gene id: 1821621:A8C75_RS02055
uniprot id: A0A1A9ETY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1821621:A8C75 RS07895
gene id: 1821621:A8C75_RS07895
uniprot id: A0A1A9EXM9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1821621:A8C75 RS00605
gene id: 1821621:A8C75_RS00605
uniprot id: A0A1A9ETN7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1821621:A8C75 RS22150
gene id: 1821621:A8C75_RS22150
uniprot id: A0A1A9F4Y2
names: Similarity
messages: Belongs to the SfsA family.

1821621:A8C75 RS10580
gene id: 1821621:A8C75_RS10580
uniprot id: A0A1A9EZG8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1821621:A8C75 RS16690
gene id: 1821621:A8C75_RS16690
uniprot id: A0A1A9F1G8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1821621:A8C75 RS18300
gene id: 1821621:A8C75_RS18300
uniprot id: A0A1A9F2Z2
names: Similarity
messages: Belongs to the Gfa family.

1821621:A8C75 RS08115
gene id: 1821621:A8C75_RS08115
uniprot id: A0A1A9EX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1821621:A8C75 RS17275
gene id: 1821621:A8C75_RS17275
uniprot id: A0A1A9F2D6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).