1810504:PG2T RS03080
gene id: 1810504:PG2T_RS03080
uniprot id: A0A1B1YR68
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1810504:PG2T RS09590
gene id: 1810504:PG2T_RS09590
uniprot id: A0A1B1YUL7
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS13700
gene id: 1810504:PG2T_RS13700
uniprot id: A0A1B1YWZ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1810504:PG2T RS02435
gene id: 1810504:PG2T_RS02435
uniprot id: A0A1B1YQU8
names: Similarity
messages: Belongs to the peptidase M16 family.

1810504:PG2T RS05345
gene id: 1810504:PG2T_RS05345
uniprot id: A0A1B1YSL9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1810504:PG2T RS02920
gene id: 1810504:PG2T_RS02920
uniprot id: A0A1B1YR44
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1810504:PG2T RS14945
gene id: 1810504:PG2T_RS14945
uniprot id: A0A1B1YXB2
names: Similarity
messages: Belongs to the GST superfamily.

1810504:PG2T RS04015
gene id: 1810504:PG2T_RS04015
uniprot id: A0A1B1YRL7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1810504:PG2T RS01030
gene id: 1810504:PG2T_RS01030
uniprot id: A0A1B1YQ73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1810504:PG2T RS03330
gene id: 1810504:PG2T_RS03330
uniprot id: A0A1B1YRK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1810504:PG2T RS05410
gene id: 1810504:PG2T_RS05410
uniprot id: A0A1B1YSJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1810504:PG2T RS09865
gene id: 1810504:PG2T_RS09865
uniprot id: A0A1B1YUR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1810504:PG2T RS11245
gene id: 1810504:PG2T_RS11245
uniprot id: A0A1B1YUZ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1810504:PG2T RS12575
gene id: 1810504:PG2T_RS12575
uniprot id: A0A1B1YVU2
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1810504:PG2T RS09735
gene id: 1810504:PG2T_RS09735
uniprot id: A0A1B1YUH5
names: Similarity
messages: Belongs to the ArsC family.

1810504:PG2T RS15190
gene id: 1810504:PG2T_RS15190
uniprot id: A0A1B1YXA6
names: Similarity
messages: Belongs to the citrate synthase family.

1810504:PG2T RS08240
gene id: 1810504:PG2T_RS08240
uniprot id: A0A1B1YTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS13870
gene id: 1810504:PG2T_RS13870
uniprot id: A0A1B1YWL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1810504:PG2T RS04865
gene id: 1810504:PG2T_RS04865
uniprot id: A0A1B1YSH7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1810504:PG2T RS09330
gene id: 1810504:PG2T_RS09330
uniprot id: A0A1B1YU76
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1810504:PG2T RS09875
gene id: 1810504:PG2T_RS09875
uniprot id: A0A1B1YUH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS01610
gene id: 1810504:PG2T_RS01610
uniprot id: A0A1B1YQH1
names: Similarity
messages: Belongs to the P(II) protein family.

1810504:PG2T RS11830
gene id: 1810504:PG2T_RS11830
uniprot id: A0A1B1YVM8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1810504:PG2T RS02565
gene id: 1810504:PG2T_RS02565
uniprot id: A0A1B1YQY1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1810504:PG2T RS07490
gene id: 1810504:PG2T_RS07490
uniprot id: A0A1B1YTF1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS11230
gene id: 1810504:PG2T_RS11230
uniprot id: A0A1B1YV77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS00140
gene id: 1810504:PG2T_RS00140
uniprot id: A0A1B1YPQ4
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

1810504:PG2T RS07080
gene id: 1810504:PG2T_RS07080
uniprot id: A0A1B1YTD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1810504:PG2T RS12745
gene id: 1810504:PG2T_RS12745
uniprot id: A0A1B1YW83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1810504:PG2T RS10710
gene id: 1810504:PG2T_RS10710
uniprot id: A0A1B1YV50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1810504:PG2T RS09720
gene id: 1810504:PG2T_RS09720
uniprot id: A0A1B1YUK7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS10040
gene id: 1810504:PG2T_RS10040
uniprot id: A0A1B1YUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1810504:PG2T RS16575
gene id: 1810504:PG2T_RS16575
uniprot id: A0A1B1YRA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1810504:PG2T RS11420
gene id: 1810504:PG2T_RS11420
uniprot id: A0A1B1YVK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1810504:PG2T RS12560
gene id: 1810504:PG2T_RS12560
uniprot id: A0A1B1YVW8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS09325
gene id: 1810504:PG2T_RS09325
uniprot id: A0A1B1YU07
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS13210
gene id: 1810504:PG2T_RS13210
uniprot id: A0A1B1YW73
names: Similarity
messages: Belongs to the P(II) protein family.

1810504:PG2T RS01885
gene id: 1810504:PG2T_RS01885
uniprot id: A0A1B1YQM7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS10145
gene id: 1810504:PG2T_RS10145
uniprot id: A0A1B1YUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

1810504:PG2T RS08090
gene id: 1810504:PG2T_RS08090
uniprot id: A0A1B1YTQ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS03670
gene id: 1810504:PG2T_RS03670
uniprot id: A0A1B1YRR5
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS01160
gene id: 1810504:PG2T_RS01160
uniprot id: A0A1B1YQ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1810504:PG2T RS15175
gene id: 1810504:PG2T_RS15175
uniprot id: A0A1B1YXE6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS08830
gene id: 1810504:PG2T_RS08830
uniprot id: A0A1B1YU61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1810504:PG2T RS08190
gene id: 1810504:PG2T_RS08190
uniprot id: A0A1B1YTG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1810504:PG2T RS09290
gene id: 1810504:PG2T_RS09290
uniprot id: A0A1B1YUR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS09285
gene id: 1810504:PG2T_RS09285
uniprot id: A0A1B1YUD8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS14665
gene id: 1810504:PG2T_RS14665
uniprot id: A0A1B1YX44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS01750
gene id: 1810504:PG2T_RS01750
uniprot id: A0A1B1YQJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1810504:PG2T RS01590
gene id: 1810504:PG2T_RS01590
uniprot id: A0A1B1YQG0
names: Similarity
messages: Belongs to the YciI family.

1810504:PG2T RS15170
gene id: 1810504:PG2T_RS15170
uniprot id: A0A1B1YX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1810504:PG2T RS03230
gene id: 1810504:PG2T_RS03230
uniprot id: A0A1B1YR96
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1810504:PG2T RS12565
gene id: 1810504:PG2T_RS12565
uniprot id: A0A1B1YWC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS07810
gene id: 1810504:PG2T_RS07810
uniprot id: A0A1B1YTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1810504:PG2T RS07230
gene id: 1810504:PG2T_RS07230
uniprot id: A0A1B1YTF2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS05610
gene id: 1810504:PG2T_RS05610
uniprot id: A0A1B1YSG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1810504:PG2T RS12290
gene id: 1810504:PG2T_RS12290
uniprot id: A0A1B1YVS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1810504:PG2T RS10450
gene id: 1810504:PG2T_RS10450
uniprot id: A0A1B1YUN3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1810504:PG2T RS09335
gene id: 1810504:PG2T_RS09335
uniprot id: A0A1B1YUF0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1810504:PG2T RS09410
gene id: 1810504:PG2T_RS09410
uniprot id: A0A1B1YUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1810504:PG2T RS07700
gene id: 1810504:PG2T_RS07700
uniprot id: A0A1B1YTN0
names: Similarity
messages: Belongs to the RutC family.

1810504:PG2T RS07595
gene id: 1810504:PG2T_RS07595
uniprot id: A0A1B1YTD6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1810504:PG2T RS14230
gene id: 1810504:PG2T_RS14230
uniprot id: A0A1B1YX15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1810504:PG2T RS12915
gene id: 1810504:PG2T_RS12915
uniprot id: A0A1B1YWB5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1810504:PG2T RS06080
gene id: 1810504:PG2T_RS06080
uniprot id: A0A1B1YSY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1810504:PG2T RS01975
gene id: 1810504:PG2T_RS01975
uniprot id: A0A1B1YQL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1810504:PG2T RS07545
gene id: 1810504:PG2T_RS07545
uniprot id: A0A1B1YTK1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1810504:PG2T RS12425
gene id: 1810504:PG2T_RS12425
uniprot id: A0A1B1YW00
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1810504:PG2T RS04355
gene id: 1810504:PG2T_RS04355
uniprot id: A0A1B1YS40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS13875
gene id: 1810504:PG2T_RS13875
uniprot id: A0A1B1YX19
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS13905
gene id: 1810504:PG2T_RS13905
uniprot id: A0A1B1YWR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1810504:PG2T RS04045
gene id: 1810504:PG2T_RS04045
uniprot id: A0A1B1YRU5
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

1810504:PG2T RS09515
gene id: 1810504:PG2T_RS09515
uniprot id: A0A1B1YU69
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1810504:PG2T RS10835
gene id: 1810504:PG2T_RS10835
uniprot id: A0A1B1YV40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1810504:PG2T RS12730
gene id: 1810504:PG2T_RS12730
uniprot id: A0A1B1YVX2
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1810504:PG2T RS07605
gene id: 1810504:PG2T_RS07605
uniprot id: A0A1B1YTT0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1810504:PG2T RS14530
gene id: 1810504:PG2T_RS14530
uniprot id: A0A1B1YWR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1810504:PG2T RS04925
gene id: 1810504:PG2T_RS04925
uniprot id: A0A1B1YS34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1810504:PG2T RS12720
gene id: 1810504:PG2T_RS12720
uniprot id: A0A1B1YWE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS05310
gene id: 1810504:PG2T_RS05310
uniprot id: A0A1B1YSH8
names: Similarity
messages: Belongs to the CutA family.

1810504:PG2T RS02455
gene id: 1810504:PG2T_RS02455
uniprot id: A0A1B1YQX3
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS11405
gene id: 1810504:PG2T_RS11405
uniprot id: A0A1B1YV91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1810504:PG2T RS00955
gene id: 1810504:PG2T_RS00955
uniprot id: A0A1B1YQ74
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS10270
gene id: 1810504:PG2T_RS10270
uniprot id: A0A1B1YUX0
names: Similarity
messages: Belongs to the YkuD family.

1810504:PG2T RS05430
gene id: 1810504:PG2T_RS05430
uniprot id: A0A1B1YSD6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1810504:PG2T RS01440
gene id: 1810504:PG2T_RS01440
uniprot id: A0A1B1YQI0
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1810504:PG2T RS09250
gene id: 1810504:PG2T_RS09250
uniprot id: A0A1B1YXT0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1810504:PG2T RS14480
gene id: 1810504:PG2T_RS14480
uniprot id: A0A1B1YWW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1810504:PG2T RS04155
gene id: 1810504:PG2T_RS04155
uniprot id: A0A1B1YRR7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1810504:PG2T RS09385
gene id: 1810504:PG2T_RS09385
uniprot id: A0A1B1YUF5
names: Similarity
messages: Belongs to the Smg family.

1810504:PG2T RS01305
gene id: 1810504:PG2T_RS01305
uniprot id: A0A1B1YX38
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1810504:PG2T RS08040
gene id: 1810504:PG2T_RS08040
uniprot id: A0A1B1YTM9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1810504:PG2T RS16295
gene id: 1810504:PG2T_RS16295
uniprot id: A0A1B1YX49
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS06255
gene id: 1810504:PG2T_RS06255
uniprot id: A0A1B1YSZ7
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1810504:PG2T RS12305
gene id: 1810504:PG2T_RS12305
uniprot id: A0A1B1YVP3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1810504:PG2T RS02495
gene id: 1810504:PG2T_RS02495
uniprot id: A0A1B1YQY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1810504:PG2T RS06365
gene id: 1810504:PG2T_RS06365
uniprot id: A0A1B1YXK1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS05515
gene id: 1810504:PG2T_RS05515
uniprot id: A0A1B1YSJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1810504:PG2T RS13230
gene id: 1810504:PG2T_RS13230
uniprot id: A0A1B1YW58
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS00725
gene id: 1810504:PG2T_RS00725
uniprot id: A0A1B1YQ15
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS00770
gene id: 1810504:PG2T_RS00770
uniprot id: A0A1B1YQ19
names: Similarity
messages: Belongs to the GST superfamily.

1810504:PG2T RS14775
gene id: 1810504:PG2T_RS14775
uniprot id: A0A1B1YX65
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1810504:PG2T RS10080
gene id: 1810504:PG2T_RS10080
uniprot id: A0A1B1YUN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1810504:PG2T RS10850
gene id: 1810504:PG2T_RS10850
uniprot id: A0A1B1YVB5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1810504:PG2T RS11175
gene id: 1810504:PG2T_RS11175
uniprot id: A0A1B1YXY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS08395
gene id: 1810504:PG2T_RS08395
uniprot id: A0A1B1YTZ9
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS08760
gene id: 1810504:PG2T_RS08760
uniprot id: A0A1B1YTS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1810504:PG2T RS06180
gene id: 1810504:PG2T_RS06180
uniprot id: A0A1B1YSU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1810504:PG2T RS08825
gene id: 1810504:PG2T_RS08825
uniprot id: A0A1B1YTY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1810504:PG2T RS06270
gene id: 1810504:PG2T_RS06270
uniprot id: A0A1B1YT02
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1810504:PG2T RS03465
gene id: 1810504:PG2T_RS03465
uniprot id: A0A1B1YRF3
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1810504:PG2T RS12590
gene id: 1810504:PG2T_RS12590
uniprot id: A0A1B1YW56
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1810504:PG2T RS09750
gene id: 1810504:PG2T_RS09750
uniprot id: A0A1B1YUP6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).

1810504:PG2T RS00870
gene id: 1810504:PG2T_RS00870
uniprot id: A0A1B1YQ77
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS09725
gene id: 1810504:PG2T_RS09725
uniprot id: A0A1B1YUY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1810504:PG2T RS04915
gene id: 1810504:PG2T_RS04915
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS07985
gene id: 1810504:PG2T_RS07985
uniprot id: A0A1B1YTU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1810504:PG2T RS11010
gene id: 1810504:PG2T_RS11010
uniprot id: A0A1B1YVH5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1810504:PG2T RS06265
gene id: 1810504:PG2T_RS06265
uniprot id: A0A1B1YSR9
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS04645
gene id: 1810504:PG2T_RS04645
uniprot id: A0A1B1YRX2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1810504:PG2T RS03195
gene id: 1810504:PG2T_RS03195
uniprot id: A0A1B1YXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1810504:PG2T RS08200
gene id: 1810504:PG2T_RS08200
uniprot id: A0A1B1YTV7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1810504:PG2T RS07885
gene id: 1810504:PG2T_RS07885
uniprot id: A0A1B1YTR5
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS02910
gene id: 1810504:PG2T_RS02910
uniprot id: A0A1B1YR62
names: Similarity
messages: Belongs to the GARS family.

1810504:PG2T RS11530
gene id: 1810504:PG2T_RS11530
uniprot id: A0A1B1YVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1810504:PG2T RS10455
gene id: 1810504:PG2T_RS10455
uniprot id: A0A1B1YUV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1810504:PG2T RS08915
gene id: 1810504:PG2T_RS08915
uniprot id: A0A1B1YU85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1810504:PG2T RS10750
gene id: 1810504:PG2T_RS10750
uniprot id: A0A1B1YVD6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1810504:PG2T RS09860
gene id: 1810504:PG2T_RS09860
uniprot id: A0A1B1YUI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS00135
gene id: 1810504:PG2T_RS00135
uniprot id: A0A1B1YPP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1810504:PG2T RS05300
gene id: 1810504:PG2T_RS05300
uniprot id: A0A1B1YSL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1810504:PG2T RS08315
gene id: 1810504:PG2T_RS08315
uniprot id: A0A1B1YTQ2
names: Similarity
messages: Belongs to the YggT family.

1810504:PG2T RS03300
gene id: 1810504:PG2T_RS03300
uniprot id: A0A1B1YRH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1810504:PG2T RS01655
gene id: 1810504:PG2T_RS01655
uniprot id: A0A1B1YQL1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1810504:PG2T RS06130
gene id: 1810504:PG2T_RS06130
uniprot id: A0A1B1YSZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1810504:PG2T RS02360
gene id: 1810504:PG2T_RS02360
uniprot id: A0A1B1YQU4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1810504:PG2T RS03105
gene id: 1810504:PG2T_RS03105
uniprot id: A0A1B1YR63
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1810504:PG2T RS07620
gene id: 1810504:PG2T_RS07620
uniprot id: A0A1B1YTG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1810504:PG2T RS03270
gene id: 1810504:PG2T_RS03270
uniprot id: A0A1B1YR99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1810504:PG2T RS09295
gene id: 1810504:PG2T_RS09295
uniprot id: A0A1B1YU32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1810504:PG2T RS11800
gene id: 1810504:PG2T_RS11800
uniprot id: A0A1B1YVD7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1810504:PG2T RS06065
gene id: 1810504:PG2T_RS06065
uniprot id: A0A1B1YSK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1810504:PG2T RS03190
gene id: 1810504:PG2T_RS03190
uniprot id: A0A1B1YR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1810504:PG2T RS06185
gene id: 1810504:PG2T_RS06185
uniprot id: A0A1B1YT08
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1810504:PG2T RS12510
gene id: 1810504:PG2T_RS12510
uniprot id: A0A1B1YWC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1810504:PG2T RS09915
gene id: 1810504:PG2T_RS09915
uniprot id: A0A1B1YUK0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1810504:PG2T RS14260
gene id: 1810504:PG2T_RS14260
uniprot id: A0A1B1YWS8
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1810504:PG2T RS09350
gene id: 1810504:PG2T_RS09350
uniprot id: A0A1B1YUB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1810504:PG2T RS06980
gene id: 1810504:PG2T_RS06980
uniprot id: A0A1B1YT41
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1810504:PG2T RS01250
gene id: 1810504:PG2T_RS01250
uniprot id: A0A1B1YQB8
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS03475
gene id: 1810504:PG2T_RS03475
uniprot id: A0A1B1YRF6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1810504:PG2T RS11125
gene id: 1810504:PG2T_RS11125
uniprot id: A0A1B1YV41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1810504:PG2T RS10770
gene id: 1810504:PG2T_RS10770
uniprot id: A0A1B1YV02
names: Similarity
messages: Belongs to the UPF0276 family.

1810504:PG2T RS10030
gene id: 1810504:PG2T_RS10030
uniprot id: A0A1B1YUM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1810504:PG2T RS06070
gene id: 1810504:PG2T_RS06070
uniprot id: A0A1B1YST0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1810504:PG2T RS02845
gene id: 1810504:PG2T_RS02845
uniprot id: A0A1B1YR49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS05660
gene id: 1810504:PG2T_RS05660
uniprot id: A0A1B1YSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1810504:PG2T RS06405
gene id: 1810504:PG2T_RS06405
uniprot id: A0A1B1YT87
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1810504:PG2T RS15020
gene id: 1810504:PG2T_RS15020
uniprot id: A0A1B1YXA0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1810504:PG2T RS11680
gene id: 1810504:PG2T_RS11680
uniprot id: A0A1B1YV36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1810504:PG2T RS10055
gene id: 1810504:PG2T_RS10055
uniprot id: A0A1B1YUE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1810504:PG2T RS05415
gene id: 1810504:PG2T_RS05415
uniprot id: A0A1B1YS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1810504:PG2T RS13950
gene id: 1810504:PG2T_RS13950
uniprot id: A0A1B1YWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1810504:PG2T RS11280
gene id: 1810504:PG2T_RS11280
uniprot id: A0A1B1YV86
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1810504:PG2T RS09115
gene id: 1810504:PG2T_RS09115
uniprot id: A0A1B1YUB0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1810504:PG2T RS12355
gene id: 1810504:PG2T_RS12355
uniprot id: A0A1B1YVQ3
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS03280
gene id: 1810504:PG2T_RS03280
uniprot id: A0A1B1YR90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1810504:PG2T RS02755
gene id: 1810504:PG2T_RS02755
uniprot id: A0A1B1YR07
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1810504:PG2T RS14410
gene id: 1810504:PG2T_RS14410
uniprot id: A0A1B1YWX6
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1810504:PG2T RS07610
gene id: 1810504:PG2T_RS07610
uniprot id: A0A1B1YTB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1810504:PG2T RS12400
gene id: 1810504:PG2T_RS12400
uniprot id: A0A1B1YWA4
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1810504:PG2T RS14240
gene id: 1810504:PG2T_RS14240
uniprot id: A0A1B1YWU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1810504:PG2T RS08755
gene id: 1810504:PG2T_RS08755
uniprot id: A0A1B1YU49
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1810504:PG2T RS02520
gene id: 1810504:PG2T_RS02520
uniprot id: A0A1B1YR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1810504:PG2T RS12130
gene id: 1810504:PG2T_RS12130
uniprot id: A0A1B1YW24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1810504:PG2T RS01100
gene id: 1810504:PG2T_RS01100
uniprot id: A0A1B1YQ78
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1810504:PG2T RS11090
gene id: 1810504:PG2T_RS11090
uniprot id: A0A1B1YVE8
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS10495
gene id: 1810504:PG2T_RS10495
uniprot id: A0A1B1YUY4
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS10260
gene id: 1810504:PG2T_RS10260
uniprot id: A0A1B1YUK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1810504:PG2T RS04365
gene id: 1810504:PG2T_RS04365
uniprot id: A0A1B1YS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1810504:PG2T RS09320
gene id: 1810504:PG2T_RS09320
uniprot id: A0A1B1YUF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1810504:PG2T RS11765
gene id: 1810504:PG2T_RS11765
uniprot id: A0A1B1YVN5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1810504:PG2T RS04210
gene id: 1810504:PG2T_RS04210
uniprot id: A0A1B1YRS7
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1810504:PG2T RS00095
gene id: 1810504:PG2T_RS00095
uniprot id: A0A1B1YPT6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1810504:PG2T RS00220
gene id: 1810504:PG2T_RS00220
uniprot id: A0A1B1YPS4
names: Similarity
messages: Belongs to the ArsC family.

1810504:PG2T RS10535
gene id: 1810504:PG2T_RS10535
uniprot id: A0A1B1YV11
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1810504:PG2T RS10345
gene id: 1810504:PG2T_RS10345
uniprot id: A0A1B1YUR9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1810504:PG2T RS12630
gene id: 1810504:PG2T_RS12630
uniprot id: A0A1B1YVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1810504:PG2T RS11635
gene id: 1810504:PG2T_RS11635
uniprot id: A0A1B1YVF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1810504:PG2T RS03735
gene id: 1810504:PG2T_RS03735
uniprot id: A0A1B1YRI3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1810504:PG2T RS05670
gene id: 1810504:PG2T_RS05670
uniprot id: A0A1B1YSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1810504:PG2T RS07065
gene id: 1810504:PG2T_RS07065
uniprot id: A0A1B1YT92
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1810504:PG2T RS02155
gene id: 1810504:PG2T_RS02155
uniprot id: A0A1B1YQR2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1810504:PG2T RS04525
gene id: 1810504:PG2T_RS04525
uniprot id: A0A1B1YS39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS01170
gene id: 1810504:PG2T_RS01170
uniprot id: A0A1B1YQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1810504:PG2T RS07580
gene id: 1810504:PG2T_RS07580
uniprot id: A0A1B1YTL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1810504:PG2T RS09300
gene id: 1810504:PG2T_RS09300
uniprot id: A0A1B1YUA2
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1810504:PG2T RS04935
gene id: 1810504:PG2T_RS04935
uniprot id: A0A1B1YS41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1810504:PG2T RS08530
gene id: 1810504:PG2T_RS08530
uniprot id: A0A1B1YTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1810504:PG2T RS06800
gene id: 1810504:PG2T_RS06800
uniprot id: A0A1B1YTF0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1810504:PG2T RS11525
gene id: 1810504:PG2T_RS11525
uniprot id: A0A1B1YVE0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS10620
gene id: 1810504:PG2T_RS10620
uniprot id: A0A1B1YV03
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS10405
gene id: 1810504:PG2T_RS10405
uniprot id: A0A1B1YV04
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1810504:PG2T RS02525
gene id: 1810504:PG2T_RS02525
uniprot id: A0A1B1YQZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS14345
gene id: 1810504:PG2T_RS14345
uniprot id: A0A1B1YWZ0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS11640
gene id: 1810504:PG2T_RS11640
uniprot id: A0A1B1YVT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1810504:PG2T RS04345
gene id: 1810504:PG2T_RS04345
uniprot id: A0A1B1YRT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1810504:PG2T RS01805
gene id: 1810504:PG2T_RS01805
uniprot id: A0A1B1YQJ1
names: Similarity
messages: Belongs to the peptidase S41A family.

1810504:PG2T RS02710
gene id: 1810504:PG2T_RS02710
uniprot id: A0A1B1YR08
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1810504:PG2T RS08345
gene id: 1810504:PG2T_RS08345
uniprot id: A0A1B1YTY7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS08035
gene id: 1810504:PG2T_RS08035
uniprot id: A0A1B1YTV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1810504:PG2T RS09885
gene id: 1810504:PG2T_RS09885
uniprot id: A0A1B1YV10
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1810504:PG2T RS05655
gene id: 1810504:PG2T_RS05655
uniprot id: A0A1B1YS76
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1810504:PG2T RS02305
gene id: 1810504:PG2T_RS02305
uniprot id: A0A1B1YQS3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1810504:PG2T RS08100
gene id: 1810504:PG2T_RS08100
uniprot id: A0A1B1YTW2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1810504:PG2T RS10650
gene id: 1810504:PG2T_RS10650
uniprot id: A0A1B1YV18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1810504:PG2T RS15065
gene id: 1810504:PG2T_RS15065
uniprot id: A0A1B1YXF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1810504:PG2T RS09525
gene id: 1810504:PG2T_RS09525
uniprot id: A0A1B1YUJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1810504:PG2T RS16865
gene id: 1810504:PG2T_RS16865
uniprot id: A0A1B1YUI1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1810504:PG2T RS05150
gene id: 1810504:PG2T_RS05150
uniprot id: A0A1B1YSF5
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1810504:PG2T RS16430
gene id: 1810504:PG2T_RS16430
uniprot id: A0A1B1YT14
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS13780
gene id: 1810504:PG2T_RS13780
uniprot id: A0A1B1YY31
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1810504:PG2T RS08735
gene id: 1810504:PG2T_RS08735
uniprot id: A0A1B1YTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1810504:PG2T RS12945
gene id: 1810504:PG2T_RS12945
uniprot id: A0A1B1YVZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1810504:PG2T RS13170
gene id: 1810504:PG2T_RS13170
uniprot id: A0A1B1YW55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1810504:PG2T RS14970
gene id: 1810504:PG2T_RS14970
uniprot id: A0A1B1YY23
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1810504:PG2T RS00345
gene id: 1810504:PG2T_RS00345
uniprot id: A0A1B1YPW1
names: Similarity
messages: Belongs to the BolA/IbaG family.

1810504:PG2T RS09390
gene id: 1810504:PG2T_RS09390
uniprot id: A0A1B1YUS8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1810504:PG2T RS09905
gene id: 1810504:PG2T_RS09905
uniprot id: A0A1B1YUR3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1810504:PG2T RS09145
gene id: 1810504:PG2T_RS09145
uniprot id: A0A1B1YUD9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS00790
gene id: 1810504:PG2T_RS00790
uniprot id: A0A1B1YQ42
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS11745
gene id: 1810504:PG2T_RS11745
uniprot id: A0A1B1YVV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1810504:PG2T RS02480
gene id: 1810504:PG2T_RS02480
uniprot id: A0A1B1YQV2
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS13005
gene id: 1810504:PG2T_RS13005
uniprot id: A0A1B1YW09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS11190
gene id: 1810504:PG2T_RS11190
uniprot id: A0A1B1YUZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS02905
gene id: 1810504:PG2T_RS02905
uniprot id: A0A1B1YRA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1810504:PG2T RS02775
gene id: 1810504:PG2T_RS02775
uniprot id: A0A1B1YR06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1810504:PG2T RS02320
gene id: 1810504:PG2T_RS02320
uniprot id: A0A1B1YQS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1810504:PG2T RS09665
gene id: 1810504:PG2T_RS09665
uniprot id: A0A1B1YUK1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1810504:PG2T RS11620
gene id: 1810504:PG2T_RS11620
uniprot id: A0A1B1YVI4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1810504:PG2T RS10615
gene id: 1810504:PG2T_RS10615
uniprot id: A0A1B1YUU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS00585
gene id: 1810504:PG2T_RS00585
uniprot id: A0A1B1YQ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1810504:PG2T RS12530
gene id: 1810504:PG2T_RS12530
uniprot id: A0A1B1YVX1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS00440
gene id: 1810504:PG2T_RS00440
uniprot id: A0A1B1YPW5
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1810504:PG2T RS03440
gene id: 1810504:PG2T_RS03440
uniprot id: A0A1B1YRD1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1810504:PG2T RS11905
gene id: 1810504:PG2T_RS11905
uniprot id: A0A1B1YVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1810504:PG2T RS03000
gene id: 1810504:PG2T_RS03000
uniprot id: A0A1B1YR74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS00105
gene id: 1810504:PG2T_RS00105
uniprot id: A0A1B1YPR7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1810504:PG2T RS02890
gene id: 1810504:PG2T_RS02890
uniprot id: A0A1B1YR54
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1810504:PG2T RS09235
gene id: 1810504:PG2T_RS09235
uniprot id: A0A1B1YU21
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS02030
gene id: 1810504:PG2T_RS02030
uniprot id: A0A1B1YQM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1810504:PG2T RS01970
gene id: 1810504:PG2T_RS01970
uniprot id: A0A1B1YQP8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1810504:PG2T RS13710
gene id: 1810504:PG2T_RS13710
uniprot id: A0A1B1YWC7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1810504:PG2T RS09225
gene id: 1810504:PG2T_RS09225
uniprot id: A0A1B1YUD0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1810504:PG2T RS12455
gene id: 1810504:PG2T_RS12455
uniprot id: A0A1B1YVU8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1810504:PG2T RS01145
gene id: 1810504:PG2T_RS01145
uniprot id: A0A1B1YQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1810504:PG2T RS01940
gene id: 1810504:PG2T_RS01940
uniprot id: A0A1B1YQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1810504:PG2T RS03145
gene id: 1810504:PG2T_RS03145
uniprot id: A0A1B1YR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1810504:PG2T RS14630
gene id: 1810504:PG2T_RS14630
uniprot id: A0A1B1YWZ2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1810504:PG2T RS14070
gene id: 1810504:PG2T_RS14070
uniprot id: A0A1B1YWR4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1810504:PG2T RS03110
gene id: 1810504:PG2T_RS03110
uniprot id: A0A1B1YR93
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS00300
gene id: 1810504:PG2T_RS00300
uniprot id: A0A1B1YPU2
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1810504:PG2T RS09840
gene id: 1810504:PG2T_RS09840
uniprot id: A0A1B1YUC6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1810504:PG2T RS11180
gene id: 1810504:PG2T_RS11180
uniprot id: A0A1B1YV70
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS06245
gene id: 1810504:PG2T_RS06245
uniprot id: A0A1B1YT15
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS11520
gene id: 1810504:PG2T_RS11520
uniprot id: A0A1B1YVB0
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1810504:PG2T RS08500
gene id: 1810504:PG2T_RS08500
uniprot id: A0A1B1YTW3
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

1810504:PG2T RS12105
gene id: 1810504:PG2T_RS12105
uniprot id: A0A1B1YVT2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS00635
gene id: 1810504:PG2T_RS00635
uniprot id: A0A1B1YQ07
names: Similarity
messages: Belongs to the universal stress protein A family.

1810504:PG2T RS13760
gene id: 1810504:PG2T_RS13760
uniprot id: A0A1B1YWC9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1810504:PG2T RS07095
gene id: 1810504:PG2T_RS07095
uniprot id: A0A1B1YT61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1810504:PG2T RS12310
gene id: 1810504:PG2T_RS12310
uniprot id: A0A1B1YVT1
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1810504:PG2T RS07710
gene id: 1810504:PG2T_RS07710
uniprot id: A0A1B1YTF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1810504:PG2T RS09745
gene id: 1810504:PG2T_RS09745
uniprot id: A0A1B1YUN4
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.

1810504:PG2T RS14460
gene id: 1810504:PG2T_RS14460
uniprot id: A0A1B1YX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1810504:PG2T RS05305
gene id: 1810504:PG2T_RS05305
uniprot id: A0A1B1YS71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1810504:PG2T RS02425
gene id: 1810504:PG2T_RS02425
uniprot id: A0A1B1YQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1810504:PG2T RS10630
gene id: 1810504:PG2T_RS10630
uniprot id: A0A1B1YVB3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS07895
gene id: 1810504:PG2T_RS07895
uniprot id: A0A1B1YTI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1810504:PG2T RS09900
gene id: 1810504:PG2T_RS09900
uniprot id: A0A1B1YUK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1810504:PG2T RS07880
gene id: 1810504:PG2T_RS07880
uniprot id: A0A1B1YTK2
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS04560
gene id: 1810504:PG2T_RS04560
uniprot id: A0A1B1YS28
names: Similarity
messages: Belongs to the GST superfamily.

1810504:PG2T RS11550
gene id: 1810504:PG2T_RS11550
uniprot id: A0A1B1YVD3
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS07830
gene id: 1810504:PG2T_RS07830
uniprot id: A0A1B1YTA9
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

1810504:PG2T RS05100
gene id: 1810504:PG2T_RS05100
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS00550
gene id: 1810504:PG2T_RS00550
uniprot id: A0A1B1YPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1810504:PG2T RS05605
gene id: 1810504:PG2T_RS05605
uniprot id: A0A1B1YS69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1810504:PG2T RS11060
gene id: 1810504:PG2T_RS11060
uniprot id: A0A1B1YV54
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS08715
gene id: 1810504:PG2T_RS08715
uniprot id: A0A1B1YTW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1810504:PG2T RS10890
gene id: 1810504:PG2T_RS10890
uniprot id: A0A1B1YUU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1810504:PG2T RS00155
gene id: 1810504:PG2T_RS00155
uniprot id: A0A1B1YPP9
names: Similarity
messages: Belongs to the HesB/IscA family.

1810504:PG2T RS05240
gene id: 1810504:PG2T_RS05240
uniprot id: A0A1B1YSE9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1810504:PG2T RS06875
gene id: 1810504:PG2T_RS06875
uniprot id: A0A1B1YSZ1
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS09985
gene id: 1810504:PG2T_RS09985
uniprot id: A0A1B1YUK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1810504:PG2T RS13090
gene id: 1810504:PG2T_RS13090
uniprot id: A0A1B1YWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1810504:PG2T RS11915
gene id: 1810504:PG2T_RS11915
uniprot id: A0A1B1YVL1
names: Similarity
messages: Belongs to the UPF0276 family.

1810504:PG2T RS08095
gene id: 1810504:PG2T_RS08095
uniprot id: A0A1B1YTP8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1810504:PG2T RS01135
gene id: 1810504:PG2T_RS01135
uniprot id: A0A1B1YQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1810504:PG2T RS14745
gene id: 1810504:PG2T_RS14745
uniprot id: A0A1B1YWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1810504:PG2T RS08695
gene id: 1810504:PG2T_RS08695
uniprot id: A0A1B1YU57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1810504:PG2T RS14250
gene id: 1810504:PG2T_RS14250
uniprot id: A0A1B1YWM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1810504:PG2T RS07320
gene id: 1810504:PG2T_RS07320
uniprot id: A0A1B1YT64
names: Similarity
messages: Belongs to the GST superfamily.

1810504:PG2T RS12070
gene id: 1810504:PG2T_RS12070
uniprot id: A0A1B1YW11
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS09930
gene id: 1810504:PG2T_RS09930
uniprot id: A0A1B1YUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1810504:PG2T RS03305
gene id: 1810504:PG2T_RS03305
uniprot id: A0A1B1YRD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1810504:PG2T RS13515
gene id: 1810504:PG2T_RS13515
uniprot id: A0A1B1YWK1
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1810504:PG2T RS11725
gene id: 1810504:PG2T_RS11725
uniprot id: A0A1B1YVK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1810504:PG2T RS05020
gene id: 1810504:PG2T_RS05020
uniprot id: A0A1B1YRZ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1810504:PG2T RS04035
gene id: 1810504:PG2T_RS04035
uniprot id: A0A1B1YRM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1810504:PG2T RS03885
gene id: 1810504:PG2T_RS03885
uniprot id: A0A1B1YRX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1810504:PG2T RS00245
gene id: 1810504:PG2T_RS00245
uniprot id: A0A1B1YPT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1810504:PG2T RS11700
gene id: 1810504:PG2T_RS11700
uniprot id: A0A1B1YVB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1810504:PG2T RS13855
gene id: 1810504:PG2T_RS13855
uniprot id: A0A1B1YWN0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS12540
gene id: 1810504:PG2T_RS12540
uniprot id: A0A1B1YW49
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1810504:PG2T RS04850
gene id: 1810504:PG2T_RS04850
uniprot id: A0A1B1YRX3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1810504:PG2T RS04740
gene id: 1810504:PG2T_RS04740
uniprot id: A0A1B1YSB1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1810504:PG2T RS12450
gene id: 1810504:PG2T_RS12450
uniprot id: A0A1B1YVT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1810504:PG2T RS01150
gene id: 1810504:PG2T_RS01150
uniprot id: A0A1B1YQ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1810504:PG2T RS12795
gene id: 1810504:PG2T_RS12795
uniprot id: A0A1B1YY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1810504:PG2T RS05725
gene id: 1810504:PG2T_RS05725
uniprot id: A0A1B1YXI6
names: Similarity
messages: Belongs to the Gfa family.

1810504:PG2T RS01920
gene id: 1810504:PG2T_RS01920
uniprot id: A0A1B1YQR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS08910
gene id: 1810504:PG2T_RS08910
uniprot id: A0A1B1YU33
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1810504:PG2T RS02380
gene id: 1810504:PG2T_RS02380
uniprot id: A0A1B1YQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1810504:PG2T RS12385
gene id: 1810504:PG2T_RS12385
uniprot id: A0A1B1YVH1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1810504:PG2T RS08930
gene id: 1810504:PG2T_RS08930
uniprot id: A0A1B1YU83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1810504:PG2T RS12845
gene id: 1810504:PG2T_RS12845
uniprot id: A0A1B1YVZ6
names: Similarity
messages: Belongs to the DapA family.

1810504:PG2T RS08880
gene id: 1810504:PG2T_RS08880
uniprot id: A0A1B1YTU0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1810504:PG2T RS01850
gene id: 1810504:PG2T_RS01850
uniprot id: A0A1B1YQK1
names: Similarity
messages: Belongs to the PrpD family.

1810504:PG2T RS03870
gene id: 1810504:PG2T_RS03870
uniprot id: A0A1B1YRK0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1810504:PG2T RS01500
gene id: 1810504:PG2T_RS01500
uniprot id: A0A1B1YQE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1810504:PG2T RS10150
gene id: 1810504:PG2T_RS10150
uniprot id: A0A1B1YUW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1810504:PG2T RS03390
gene id: 1810504:PG2T_RS03390
uniprot id: A0A1B1YRB1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1810504:PG2T RS08030
gene id: 1810504:PG2T_RS08030
uniprot id: A0A1B1YTN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1810504:PG2T RS11120
gene id: 1810504:PG2T_RS11120
uniprot id: A0A1B1YUY2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1810504:PG2T RS03040
gene id: 1810504:PG2T_RS03040
uniprot id: A0A1B1YRA7
names: Similarity
messages: Belongs to the HypE family.

1810504:PG2T RS03495
gene id: 1810504:PG2T_RS03495
uniprot id: A0A1B1YRE0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1810504:PG2T RS07630
gene id: 1810504:PG2T_RS07630
uniprot id: A0A1B1YTP1
names: Similarity
messages: Belongs to the CinA family.

1810504:PG2T RS00965
gene id: 1810504:PG2T_RS00965
uniprot id: A0A1B1YQ67
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1810504:PG2T RS08845
gene id: 1810504:PG2T_RS08845
uniprot id: A0A1B1YU20
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1810504:PG2T RS07475
gene id: 1810504:PG2T_RS07475
uniprot id: A0A1B1YTJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS02625
gene id: 1810504:PG2T_RS02625
uniprot id: A0A1B1YR04
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1810504:PG2T RS00500
gene id: 1810504:PG2T_RS00500
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS04800
gene id: 1810504:PG2T_RS04800
uniprot id: A0A1B1YS89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1810504:PG2T RS09045
gene id: 1810504:PG2T_RS09045
uniprot id: A0A1B1YU34
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1810504:PG2T RS11390
gene id: 1810504:PG2T_RS11390
uniprot id: A0A1B1YVA9
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1810504:PG2T RS07295
gene id: 1810504:PG2T_RS07295
uniprot id: A0A1B1YTG2
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS03045
gene id: 1810504:PG2T_RS03045
uniprot id: A0A1B1YR53
names: Similarity
messages: Belongs to the HypD family.

1810504:PG2T RS03315
gene id: 1810504:PG2T_RS03315
uniprot id: A0A1B1YRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1810504:PG2T RS04680
gene id: 1810504:PG2T_RS04680
uniprot id: A0A1B1YS44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1810504:PG2T RS08780
gene id: 1810504:PG2T_RS08780
uniprot id: A0A1B1YTV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS08920
gene id: 1810504:PG2T_RS08920
uniprot id: A0A1B1YU93
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1810504:PG2T RS15005
gene id: 1810504:PG2T_RS15005
uniprot id: A0A1B1YWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1810504:PG2T RS03290
gene id: 1810504:PG2T_RS03290
uniprot id: A0A1B1YRA5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1810504:PG2T RS11685
gene id: 1810504:PG2T_RS11685
uniprot id: A0A1B1YVF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1810504:PG2T RS11610
gene id: 1810504:PG2T_RS11610
uniprot id: A0A1B1YVK0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS06855
gene id: 1810504:PG2T_RS06855
uniprot id: A0A1B1YSU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1810504:PG2T RS02545
gene id: 1810504:PG2T_RS02545
uniprot id: A0A1B1YXN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1810504:PG2T RS05435
gene id: 1810504:PG2T_RS05435
uniprot id: A0A1B1YSD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1810504:PG2T RS00945
gene id: 1810504:PG2T_RS00945
uniprot id: A0A1B1YQ75
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS06045
gene id: 1810504:PG2T_RS06045
uniprot id: A0A1B1YSM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS03355
gene id: 1810504:PG2T_RS03355
uniprot id: A0A1B1YRI1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1810504:PG2T RS07240
gene id: 1810504:PG2T_RS07240
uniprot id: A0A1B1YT80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1810504:PG2T RS08050
gene id: 1810504:PG2T_RS08050
uniprot id: A0A1B1YTE6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS06165
gene id: 1810504:PG2T_RS06165
uniprot id: A0A1B1YT48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS08445
gene id: 1810504:PG2T_RS08445
uniprot id: A0A1B1YU10
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS01495
gene id: 1810504:PG2T_RS01495
uniprot id: A0A1B1YQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS13895
gene id: 1810504:PG2T_RS13895
uniprot id: A0A1B1YWS6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1810504:PG2T RS14265
gene id: 1810504:PG2T_RS14265
uniprot id: A0A1B1YX81
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS02830
gene id: 1810504:PG2T_RS02830
uniprot id: A0A1B1YR17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1810504:PG2T RS02605
gene id: 1810504:PG2T_RS02605
uniprot id: A0A1B1YR31
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1810504:PG2T RS10980
gene id: 1810504:PG2T_RS10980
uniprot id: A0A1B1YVD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1810504:PG2T RS07155
gene id: 1810504:PG2T_RS07155
uniprot id: A0A1B1YTG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1810504:PG2T RS08720
gene id: 1810504:PG2T_RS08720
uniprot id: A0A1B1YU39
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1810504:PG2T RS04065
gene id: 1810504:PG2T_RS04065
uniprot id: A0A1B1YRN0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1810504:PG2T RS05615
gene id: 1810504:PG2T_RS05615
uniprot id: A0A1B1YSM2
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS15185
gene id: 1810504:PG2T_RS15185
uniprot id: A0A1B1YXC7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1810504:PG2T RS12780
gene id: 1810504:PG2T_RS12780
uniprot id: A0A1B1YVX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1810504:PG2T RS04000
gene id: 1810504:PG2T_RS04000
uniprot id: A0A1B1YRM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1810504:PG2T RS01045
gene id: 1810504:PG2T_RS01045
uniprot id: A0A1B1YQ69
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS04405
gene id: 1810504:PG2T_RS04405
uniprot id: A0A1B1YRT4
names: Similarity
messages: Belongs to the BolA/IbaG family.

1810504:PG2T RS10815
gene id: 1810504:PG2T_RS10815
uniprot id: A0A1B1YVE6
names: Similarity
messages: Belongs to the YkuD family.

1810504:PG2T RS09910
gene id: 1810504:PG2T_RS09910
uniprot id: A0A1B1YUS7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1810504:PG2T RS06030
gene id: 1810504:PG2T_RS06030
uniprot id: A0A1B1YSJ1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1810504:PG2T RS04370
gene id: 1810504:PG2T_RS04370
uniprot id: A0A1B1YRT0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1810504:PG2T RS04735
gene id: 1810504:PG2T_RS04735
uniprot id: A0A1B1YS02
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1810504:PG2T RS11965
gene id: 1810504:PG2T_RS11965
uniprot id: A0A1B1YVG8
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1810504:PG2T RS08875
gene id: 1810504:PG2T_RS08875
uniprot id: A0A1B1YU70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1810504:PG2T RS02400
gene id: 1810504:PG2T_RS02400
uniprot id: A0A1B1YQW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1810504:PG2T RS15205
gene id: 1810504:PG2T_RS15205
uniprot id: A0A1B1YX83
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1810504:PG2T RS00430
gene id: 1810504:PG2T_RS00430
uniprot id: A0A1B1YPX4
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1810504:PG2T RS08990
gene id: 1810504:PG2T_RS08990
uniprot id: A0A1B1YU98
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1810504:PG2T RS06155
gene id: 1810504:PG2T_RS06155
uniprot id: A0A1B1YSP8
names: Subcellular Location Annotation
messages: Periplasm

1810504:PG2T RS01475
gene id: 1810504:PG2T_RS01475
uniprot id: A0A1B1YQF1
names: Similarity
messages: Belongs to the DapA family.

1810504:PG2T RS12185
gene id: 1810504:PG2T_RS12185
uniprot id: A0A1B1YVK9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1810504:PG2T RS05575
gene id: 1810504:PG2T_RS05575
uniprot id: A0A1B1YSC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1810504:PG2T RS14810
gene id: 1810504:PG2T_RS14810
uniprot id: A0A1B1YWU6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1810504:PG2T RS10955
gene id: 1810504:PG2T_RS10955
uniprot id: A0A1B1YUV6
names: Similarity
messages: Belongs to the TPP enzyme family.

1810504:PG2T RS12430
gene id: 1810504:PG2T_RS12430
uniprot id: A0A1B1YW31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1810504:PG2T RS14295
gene id: 1810504:PG2T_RS14295
uniprot id: A0A1B1YWY0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1810504:PG2T RS10830
gene id: 1810504:PG2T_RS10830
uniprot id: A0A1B1YV08
names: Similarity
messages: Belongs to the BolA/IbaG family.

1810504:PG2T RS09305
gene id: 1810504:PG2T_RS09305
uniprot id: A0A1B1YUG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1810504:PG2T RS03055
gene id: 1810504:PG2T_RS03055
uniprot id: A0A1B1YR84
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1810504:PG2T RS00795
gene id: 1810504:PG2T_RS00795
uniprot id: A0A1B1YQ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1810504:PG2T RS00760
gene id: 1810504:PG2T_RS00760
uniprot id: A0A1B1YXA1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1810504:PG2T RS01300
gene id: 1810504:PG2T_RS01300
uniprot id: A0A1B1YQC0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS10410
gene id: 1810504:PG2T_RS10410
uniprot id: A0A1B1YUT0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1810504:PG2T RS07590
gene id: 1810504:PG2T_RS07590
uniprot id: A0A1B1YT71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1810504:PG2T RS11985
gene id: 1810504:PG2T_RS11985
uniprot id: A0A1B1YVS4
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1810504:PG2T RS08625
gene id: 1810504:PG2T_RS08625
uniprot id: A0A1B1YU38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1810504:PG2T RS09535
gene id: 1810504:PG2T_RS09535
uniprot id: A0A1B1YUC8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1810504:PG2T RS12115
gene id: 1810504:PG2T_RS12115
uniprot id: A0A1B1YVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1810504:PG2T RS05600
gene id: 1810504:PG2T_RS05600
uniprot id: A0A1B1YSL8
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS05665
gene id: 1810504:PG2T_RS05665
uniprot id: A0A1B1YXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1810504:PG2T RS11425
gene id: 1810504:PG2T_RS11425
uniprot id: A0A1B1YVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1810504:PG2T RS01605
gene id: 1810504:PG2T_RS01605
uniprot id: A0A1B1YQF9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1810504:PG2T RS13010
gene id: 1810504:PG2T_RS13010
uniprot id: A0A1B1YW22
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1810504:PG2T RS02885
gene id: 1810504:PG2T_RS02885
uniprot id: A0A1B1YR28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1810504:PG2T RS01530
gene id: 1810504:PG2T_RS01530
uniprot id: A0A1B1YQE6
names: Subcellular Location Annotation
messages: Cell inner membrane

1810504:PG2T RS04750
gene id: 1810504:PG2T_RS04750
uniprot id: A0A1B1YS80
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1810504:PG2T RS10395
gene id: 1810504:PG2T_RS10395
uniprot id: A0A1B1YUU5
names: Similarity
messages: Belongs to the peptidase M24B family.

1810504:PG2T RS02330
gene id: 1810504:PG2T_RS02330
uniprot id: A0A1B1YQU3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1810504:PG2T RS12580
gene id: 1810504:PG2T_RS12580
uniprot id: A0A1B1YVY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1810504:PG2T RS12460
gene id: 1810504:PG2T_RS12460
uniprot id: A0A1B1YWB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1810504:PG2T RS07395
gene id: 1810504:PG2T_RS07395
uniprot id: A0A1B1YT63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1810504:PG2T RS09945
gene id: 1810504:PG2T_RS09945
uniprot id: A0A1B1YV17
names: Similarity
messages: Belongs to the aspartokinase family.

1810504:PG2T RS03395
gene id: 1810504:PG2T_RS03395
uniprot id: A0A1B1YRE3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1810504:PG2T RS07245
gene id: 1810504:PG2T_RS07245
uniprot id: A0A1B1YTF5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1810504:PG2T RS00130
gene id: 1810504:PG2T_RS00130
uniprot id: A0A1B1YPS7
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1810504:PG2T RS09700
gene id: 1810504:PG2T_RS09700
uniprot id: A0A1B1YUF7
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1810504:PG2T RS12655
gene id: 1810504:PG2T_RS12655
uniprot id: A0A1B1YVY4
names: Similarity
messages: Belongs to the histone deacetylase family.

1810504:PG2T RS09795
gene id: 1810504:PG2T_RS09795
uniprot id: A0A1B1YUI5
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS04670
gene id: 1810504:PG2T_RS04670
uniprot id: A0A1B1YSD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1810504:PG2T RS11720
gene id: 1810504:PG2T_RS11720
uniprot id: A0A1B1YVQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1810504:PG2T RS10420
gene id: 1810504:PG2T_RS10420
uniprot id: A0A1B1YUZ6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1810504:PG2T RS06110
gene id: 1810504:PG2T_RS06110
uniprot id: A0A1B1YT39
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS03050
gene id: 1810504:PG2T_RS03050
uniprot id: A0A1B1YX66
names: Similarity
messages: Belongs to the HupF/HypC family.

1810504:PG2T RS10485
gene id: 1810504:PG2T_RS10485
uniprot id: A0A1B1YUS3
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS11675
gene id: 1810504:PG2T_RS11675
uniprot id: A0A1B1YVJ7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1810504:PG2T RS10525
gene id: 1810504:PG2T_RS10525
uniprot id: A0A1B1YV20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1810504:PG2T RS10905
gene id: 1810504:PG2T_RS10905
uniprot id: A0A1B1YV15
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1810504:PG2T RS05065
gene id: 1810504:PG2T_RS05065
uniprot id: A0A1B1YXP9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1810504:PG2T RS03585
gene id: 1810504:PG2T_RS03585
uniprot id: A0A1B1YRG1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1810504:PG2T RS08195
gene id: 1810504:PG2T_RS08195
uniprot id: A0A1B1YTN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1810504:PG2T RS08475
gene id: 1810504:PG2T_RS08475
uniprot id: A0A1B1YTT2
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1810504:PG2T RS10440
gene id: 1810504:PG2T_RS10440
uniprot id: A0A1B1YUX5
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.

1810504:PG2T RS07260
gene id: 1810504:PG2T_RS07260
uniprot id: A0A1B1YTB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1810504:PG2T RS08670
gene id: 1810504:PG2T_RS08670
uniprot id: A0A1B1YU27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1810504:PG2T RS09850
gene id: 1810504:PG2T_RS09850
uniprot id: A0A1B1YUQ3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1810504:PG2T RS14210
gene id: 1810504:PG2T_RS14210
uniprot id: A0A1B1YWJ1
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1810504:PG2T RS14645
gene id: 1810504:PG2T_RS14645
uniprot id: A0A1B1YWR6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1810504:PG2T RS14290
gene id: 1810504:PG2T_RS14290
uniprot id: A0A1B1YX29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS09520
gene id: 1810504:PG2T_RS09520
uniprot id: A0A1B1YUE2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1810504:PG2T RS07050
gene id: 1810504:PG2T_RS07050
uniprot id: A0A1B1YTJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS14855
gene id: 1810504:PG2T_RS14855
uniprot id: A0A1B1YX28
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS13225
gene id: 1810504:PG2T_RS13225
uniprot id: A0A1B1YW53
names: Similarity
messages: Belongs to the thioredoxin family.

1810504:PG2T RS10095
gene id: 1810504:PG2T_RS10095
uniprot id: A0A1B1YUM9
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS11670
gene id: 1810504:PG2T_RS11670
uniprot id: A0A1B1YVP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1810504:PG2T RS11600
gene id: 1810504:PG2T_RS11600
uniprot id: A0A1B1YVF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1810504:PG2T RS05275
gene id: 1810504:PG2T_RS05275
uniprot id: A0A1B1YSA9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS02255
gene id: 1810504:PG2T_RS02255
uniprot id: A0A1B1YQS0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1810504:PG2T RS00125
gene id: 1810504:PG2T_RS00125
uniprot id: A0A1B1YPS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1810504:PG2T RS11570
gene id: 1810504:PG2T_RS11570
uniprot id: A0A1B1YV95
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1810504:PG2T RS09470
gene id: 1810504:PG2T_RS09470
uniprot id: A0A1B1YUJ7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1810504:PG2T RS01415
gene id: 1810504:PG2T_RS01415
uniprot id: A0A1B1YQC7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1810504:PG2T RS04835
gene id: 1810504:PG2T_RS04835
uniprot id: A0A1B1YSD3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1810504:PG2T RS08810
gene id: 1810504:PG2T_RS08810
uniprot id: A0A1B1YU60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1810504:PG2T RS08765
gene id: 1810504:PG2T_RS08765
uniprot id: A0A1B1YTX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1810504:PG2T RS05470
gene id: 1810504:PG2T_RS05470
uniprot id: A0A1B1YSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS08535
gene id: 1810504:PG2T_RS08535
uniprot id: A0A1B1YTU3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1810504:PG2T RS10110
gene id: 1810504:PG2T_RS10110
uniprot id: A0A1B1YUL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1810504:PG2T RS13885
gene id: 1810504:PG2T_RS13885
uniprot id: A0A1B1YWE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1810504:PG2T RS00925
gene id: 1810504:PG2T_RS00925
uniprot id: A0A1B1YQ83
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1810504:PG2T RS11790
gene id: 1810504:PG2T_RS11790
uniprot id: A0A1B1YVI7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1810504:PG2T RS05405
gene id: 1810504:PG2T_RS05405
uniprot id: A0A1B1YS90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1810504:PG2T RS02390
gene id: 1810504:PG2T_RS02390
uniprot id: A0A1B1YQU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1810504:PG2T RS01935
gene id: 1810504:PG2T_RS01935
uniprot id: A0A1B1YQL9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1810504:PG2T RS02265
gene id: 1810504:PG2T_RS02265
uniprot id: A0A1B1YQW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1810504:PG2T RS14550
gene id: 1810504:PG2T_RS14550
uniprot id: A0A1B1YWP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS01315
gene id: 1810504:PG2T_RS01315
uniprot id: A0A1B1YQF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1810504:PG2T RS04570
gene id: 1810504:PG2T_RS04570
uniprot id: A0A1B1YS78
names: Similarity
messages: Belongs to the DapA family.

1810504:PG2T RS00175
gene id: 1810504:PG2T_RS00175
uniprot id: A0A1B1YPV4
names: Similarity
messages: Belongs to the NifZ family.

1810504:PG2T RS03180
gene id: 1810504:PG2T_RS03180
uniprot id: A0A1B1YRF4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1810504:PG2T RS07255
gene id: 1810504:PG2T_RS07255
uniprot id: A0A1B1YT53
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1810504:PG2T RS05955
gene id: 1810504:PG2T_RS05955
uniprot id: A0A1B1YT03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1810504:PG2T RS00045
gene id: 1810504:PG2T_RS00045
uniprot id: A0A1B1YPS8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1810504:PG2T RS05685
gene id: 1810504:PG2T_RS05685
uniprot id: A0A1B1YSL6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1810504:PG2T RS07860
gene id: 1810504:PG2T_RS07860
uniprot id: A0A1B1YTL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS06795
gene id: 1810504:PG2T_RS06795
uniprot id: A0A1B1YT88
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1810504:PG2T RS09425
gene id: 1810504:PG2T_RS09425
uniprot id: A0A1B1YU28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1810504:PG2T RS03530
gene id: 1810504:PG2T_RS03530
uniprot id: A0A1B1YRG5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1810504:PG2T RS04290
gene id: 1810504:PG2T_RS04290
uniprot id: A0A1B1YRR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS10780
gene id: 1810504:PG2T_RS10780
uniprot id: A0A1B1YV60
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1810504:PG2T RS01915
gene id: 1810504:PG2T_RS01915
uniprot id: A0A1B1YQP3
names: Similarity
messages: Belongs to the SCO1/2 family.

1810504:PG2T RS11695
gene id: 1810504:PG2T_RS11695
uniprot id: A0A1B1YVU6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1810504:PG2T RS09000
gene id: 1810504:PG2T_RS09000
uniprot id: A0A1B1YU14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1810504:PG2T RS00230
gene id: 1810504:PG2T_RS00230
uniprot id: A0A1B1YPU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS10385
gene id: 1810504:PG2T_RS10385
uniprot id: A0A1B1YV74
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1810504:PG2T RS01425
gene id: 1810504:PG2T_RS01425
uniprot id: A0A1B1YQC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1810504:PG2T RS00970
gene id: 1810504:PG2T_RS00970
uniprot id: A0A1B1YQ44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1810504:PG2T RS03005
gene id: 1810504:PG2T_RS03005
uniprot id: A0A1B1YR57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1810504:PG2T RS03615
gene id: 1810504:PG2T_RS03615
uniprot id: A0A1B1YRF8
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS02600
gene id: 1810504:PG2T_RS02600
uniprot id: A0A1B1YQX7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1810504:PG2T RS02555
gene id: 1810504:PG2T_RS02555
uniprot id: A0A1B1YQW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1810504:PG2T RS08745
gene id: 1810504:PG2T_RS08745
uniprot id: A0A1B1YU66
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1810504:PG2T RS05715
gene id: 1810504:PG2T_RS05715
uniprot id: A0A1B1YSH9
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1810504:PG2T RS14975
gene id: 1810504:PG2T_RS14975
uniprot id: A0A1B1YX48
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1810504:PG2T RS05940
gene id: 1810504:PG2T_RS05940
uniprot id: A0A1B1YSC4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1810504:PG2T RS00455
gene id: 1810504:PG2T_RS00455
uniprot id: A0A1B1YPX9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS10115
gene id: 1810504:PG2T_RS10115
uniprot id: A0A1B1YUS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS04305
gene id: 1810504:PG2T_RS04305
uniprot id: A0A1B1YRQ1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1810504:PG2T RS07675
gene id: 1810504:PG2T_RS07675
uniprot id: A0A1B1YTC0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1810504:PG2T RS00605
gene id: 1810504:PG2T_RS00605
uniprot id: A0A1B1YPZ1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1810504:PG2T RS07070
gene id: 1810504:PG2T_RS07070
uniprot id: A0A1B1YTF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1810504:PG2T RS11380
gene id: 1810504:PG2T_RS11380
uniprot id: A0A1B1YV06
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS09655
gene id: 1810504:PG2T_RS09655
uniprot id: A0A1B1YU72
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1810504:PG2T RS12520
gene id: 1810504:PG2T_RS12520
uniprot id: A0A1B1YVS9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1810504:PG2T RS14125
gene id: 1810504:PG2T_RS14125
uniprot id: A0A1B1YWS3
names: Similarity
messages: Belongs to the universal stress protein A family.

1810504:PG2T RS01380
gene id: 1810504:PG2T_RS01380
uniprot id: A0A1B1YQD6
names: Similarity
messages: Belongs to the peptidase M1 family.

1810504:PG2T RS07690
gene id: 1810504:PG2T_RS07690
uniprot id: A0A1B1YTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1810504:PG2T RS00645
gene id: 1810504:PG2T_RS00645
uniprot id: A0A1B1YQ30
names: Similarity
messages: Belongs to the DapA family.

1810504:PG2T RS02385
gene id: 1810504:PG2T_RS02385
uniprot id: A0A1B1YQW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1810504:PG2T RS08740
gene id: 1810504:PG2T_RS08740
uniprot id: A0A1B1YU58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1810504:PG2T RS11740
gene id: 1810504:PG2T_RS11740
uniprot id: A0A1B1YVH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1810504:PG2T RS08045
gene id: 1810504:PG2T_RS08045
uniprot id: A0A1B1YTU2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1810504:PG2T RS13685
gene id: 1810504:PG2T_RS13685
uniprot id: A0A1B1YW57
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS14925
gene id: 1810504:PG2T_RS14925
uniprot id: A0A1B1YX37
names: Similarity
messages: Belongs to the YfgM family.

1810504:PG2T RS00255
gene id: 1810504:PG2T_RS00255
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS09975
gene id: 1810504:PG2T_RS09975
uniprot id: A0A1B1YUS2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1810504:PG2T RS13525
gene id: 1810504:PG2T_RS13525
uniprot id: A0A1B1YW29
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1810504:PG2T RS09835
gene id: 1810504:PG2T_RS09835
uniprot id: A0A1B1YV00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1810504:PG2T RS10265
gene id: 1810504:PG2T_RS10265
uniprot id: A0A1B1YUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS13035
gene id: 1810504:PG2T_RS13035
uniprot id: A0A1B1YWD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1810504:PG2T RS13690
gene id: 1810504:PG2T_RS13690
uniprot id: A0A1B1YWD9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1810504:PG2T RS11750
gene id: 1810504:PG2T_RS11750
uniprot id: A0A1B1YVC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1810504:PG2T RS14695
gene id: 1810504:PG2T_RS14695
uniprot id: A0A1B1YWS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1810504:PG2T RS00930
gene id: 1810504:PG2T_RS00930
uniprot id: A0A1B1YQ62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1810504:PG2T RS09440
gene id: 1810504:PG2T_RS09440
uniprot id: A0A1B1YUG3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1810504:PG2T RS02550
gene id: 1810504:PG2T_RS02550
uniprot id: A0A1B1YR20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1810504:PG2T RS13625
gene id: 1810504:PG2T_RS13625
uniprot id: A0A1B1YW52
names: Similarity
messages: Belongs to the universal stress protein A family.

1810504:PG2T RS07995
gene id: 1810504:PG2T_RS07995
uniprot id: A0A1B1YTT4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1810504:PG2T RS07465
gene id: 1810504:PG2T_RS07465
uniprot id: A0A1B1YT47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS11945
gene id: 1810504:PG2T_RS11945
uniprot id: A0A1B1YV87
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1810504:PG2T RS12615
gene id: 1810504:PG2T_RS12615
uniprot id: A0A1B1YWD5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS16810
gene id: 1810504:PG2T_RS16810
uniprot id: A0A1B1YRF7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1810504:PG2T RS11460
gene id: 1810504:PG2T_RS11460
uniprot id: A0A1B1YVD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1810504:PG2T RS04520
gene id: 1810504:PG2T_RS04520
uniprot id: A0A1B1YRU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS14930
gene id: 1810504:PG2T_RS14930
uniprot id: A0A1B1YXI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1810504:PG2T RS02940
gene id: 1810504:PG2T_RS02940
uniprot id: A0A1B1YR37
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS12685
gene id: 1810504:PG2T_RS12685
uniprot id: A0A1B1YW06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

1810504:PG2T RS06330
gene id: 1810504:PG2T_RS06330
uniprot id: A0A1B1YSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1810504:PG2T RS10970
gene id: 1810504:PG2T_RS10970
uniprot id: A0A1B1YXY1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1810504:PG2T RS14670
gene id: 1810504:PG2T_RS14670
uniprot id: A0A1B1YX23
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS05460
gene id: 1810504:PG2T_RS05460
uniprot id: A0A1B1YSN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS07725
gene id: 1810504:PG2T_RS07725
uniprot id: A0A1B1YTC4
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS06035
gene id: 1810504:PG2T_RS06035
uniprot id: A0A1B1YSV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1810504:PG2T RS07865
gene id: 1810504:PG2T_RS07865
uniprot id: A0A1B1YTL2
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1810504:PG2T RS14560
gene id: 1810504:PG2T_RS14560
uniprot id: A0A1B1YX45
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1810504:PG2T RS09200
gene id: 1810504:PG2T_RS09200
uniprot id: A0A1B1YUE6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1810504:PG2T RS14590
gene id: 1810504:PG2T_RS14590
uniprot id: A0A1B1YXD7
names: Similarity
messages: Belongs to the HesB/IscA family.

1810504:PG2T RS03665
gene id: 1810504:PG2T_RS03665
uniprot id: A0A1B1YRG9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1810504:PG2T RS04465
gene id: 1810504:PG2T_RS04465
uniprot id: A0A1B1YRT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1810504:PG2T RS03525
gene id: 1810504:PG2T_RS03525
uniprot id: A0A1B1YRE8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1810504:PG2T RS10805
gene id: 1810504:PG2T_RS10805
uniprot id: A0A1B1YUX6
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1810504:PG2T RS07500
gene id: 1810504:PG2T_RS07500
uniprot id: A0A1B1YTF4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS03565
gene id: 1810504:PG2T_RS03565
uniprot id: A0A1B1YRP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1810504:PG2T RS14905
gene id: 1810504:PG2T_RS14905
uniprot id: A0A1B1YX85
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1810504:PG2T RS11440
gene id: 1810504:PG2T_RS11440
uniprot id: A0A1B1YVC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1810504:PG2T RS11870
gene id: 1810504:PG2T_RS11870
uniprot id: A0A1B1YVQ5
names: Similarity
messages: Belongs to the GST superfamily.

1810504:PG2T RS12405
gene id: 1810504:PG2T_RS12405
uniprot id: A0A1B1YVQ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1810504:PG2T RS04385
gene id: 1810504:PG2T_RS04385
uniprot id: A0A1B1YS77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1810504:PG2T RS10635
gene id: 1810504:PG2T_RS10635
uniprot id: A0A1B1YUR1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1810504:PG2T RS09825
gene id: 1810504:PG2T_RS09825
uniprot id: A0A1B1YUG8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1810504:PG2T RS13220
gene id: 1810504:PG2T_RS13220
uniprot id: A0A1B1YWQ7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1810504:PG2T RS05730
gene id: 1810504:PG2T_RS05730
uniprot id: A0A1B1YSW2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1810504:PG2T RS01545
gene id: 1810504:PG2T_RS01545
uniprot id: A0A1B1YQH2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1810504:PG2T RS15090
gene id: 1810504:PG2T_RS15090
uniprot id: A0A1B1YX68
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS02290
gene id: 1810504:PG2T_RS02290
uniprot id: A0A1B1YQY6
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS06040
gene id: 1810504:PG2T_RS06040
uniprot id: A0A1B1YSE3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS07555
gene id: 1810504:PG2T_RS07555
uniprot id: A0A1B1YTA2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1810504:PG2T RS14370
gene id: 1810504:PG2T_RS14370
uniprot id: A0A1B1YWU4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1810504:PG2T RS00320
gene id: 1810504:PG2T_RS00320
uniprot id: A0A1B1YPV1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1810504:PG2T RS15165
gene id: 1810504:PG2T_RS15165
uniprot id: A0A1B1YX02
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1810504:PG2T RS07150
gene id: 1810504:PG2T_RS07150
uniprot id: A0A1B1YTA0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1810504:PG2T RS11775
gene id: 1810504:PG2T_RS11775
uniprot id: A0A1B1YVL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1810504:PG2T RS08270
gene id: 1810504:PG2T_RS08270
uniprot id: A0A1B1YU80
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS13630
gene id: 1810504:PG2T_RS13630
uniprot id: A0A1B1YWD2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1810504:PG2T RS09355
gene id: 1810504:PG2T_RS09355
uniprot id: A0A1B1YUG4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1810504:PG2T RS05130
gene id: 1810504:PG2T_RS05130
uniprot id: A0A1B1YS63
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1810504:PG2T RS08680
gene id: 1810504:PG2T_RS08680
uniprot id: A0A1B1YTT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1810504:PG2T RS16005
gene id: 1810504:PG2T_RS16005
uniprot id: A0A1B1YSE5
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS10310
gene id: 1810504:PG2T_RS10310
uniprot id: A0A1B1YUV9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1810504:PG2T RS11950
gene id: 1810504:PG2T_RS11950
uniprot id: A0A1B1YVK4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1810504:PG2T RS13235
gene id: 1810504:PG2T_RS13235
uniprot id: A0A1B1YWB8
names: Caution
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS09170
gene id: 1810504:PG2T_RS09170
uniprot id: A0A1B1YUC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1810504:PG2T RS08330
gene id: 1810504:PG2T_RS08330
uniprot id: A0A1B1YTM6
names: Similarity
messages: Belongs to the GSP E family.

1810504:PG2T RS13370
gene id: 1810504:PG2T_RS13370
uniprot id: A0A1B1YW02
names: Similarity
messages: Belongs to the NodU/CmcH family.

1810504:PG2T RS07390
gene id: 1810504:PG2T_RS07390
uniprot id: A0A1B1YTJ8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1810504:PG2T RS07190
gene id: 1810504:PG2T_RS07190
uniprot id: A0A1B1YTE0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1810504:PG2T RS05565
gene id: 1810504:PG2T_RS05565
uniprot id: A0A1B1YSF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1810504:PG2T RS10875
gene id: 1810504:PG2T_RS10875
uniprot id: A0A1B1YV32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1810504:PG2T RS00675
gene id: 1810504:PG2T_RS00675
uniprot id: A0A1B1YQ17
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1810504:PG2T RS11760
gene id: 1810504:PG2T_RS11760
uniprot id: A0A1B1YVI3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1810504:PG2T RS10185
gene id: 1810504:PG2T_RS10185
uniprot id: A0A1B1YUJ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1810504:PG2T RS16395
gene id: 1810504:PG2T_RS16395
uniprot id: A0A1B1YRD8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1810504:PG2T RS01085
gene id: 1810504:PG2T_RS01085
uniprot id: A0A1B1YQ89
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS07085
gene id: 1810504:PG2T_RS07085
uniprot id: A0A1B1YSY9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1810504:PG2T RS00480
gene id: 1810504:PG2T_RS00480
uniprot id: A0A1B1YPX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1810504:PG2T RS08205
gene id: 1810504:PG2T_RS08205
uniprot id: A0A1B1YU75
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1810504:PG2T RS07195
gene id: 1810504:PG2T_RS07195
uniprot id: A0A1B1YTK8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1810504:PG2T RS03350
gene id: 1810504:PG2T_RS03350
uniprot id: A0A1B1YRE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1810504:PG2T RS13640
gene id: 1810504:PG2T_RS13640
uniprot id: A0A1B1YWY2
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1810504:PG2T RS10470
gene id: 1810504:PG2T_RS10470
uniprot id: A0A1B1YUU3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1810504:PG2T RS00040
gene id: 1810504:PG2T_RS00040
uniprot id: A0A1B1YXD6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1810504:PG2T RS08275
gene id: 1810504:PG2T_RS08275
uniprot id: A0A1B1YTL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1810504:PG2T RS11785
gene id: 1810504:PG2T_RS11785
uniprot id: A0A1B1YVH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1810504:PG2T RS10665
gene id: 1810504:PG2T_RS10665
uniprot id: A0A1B1YV29
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1810504:PG2T RS07730
gene id: 1810504:PG2T_RS07730
uniprot id: A0A1B1YTJ0
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS10990
gene id: 1810504:PG2T_RS10990
uniprot id: A0A1B1YV73
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1810504:PG2T RS15120
gene id: 1810504:PG2T_RS15120
uniprot id: A0A1B1YXH0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS07815
gene id: 1810504:PG2T_RS07815
uniprot id: A0A1B1YTQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1810504:PG2T RS06885
gene id: 1810504:PG2T_RS06885
uniprot id: A0A1B1YT62
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1810504:PG2T RS14355
gene id: 1810504:PG2T_RS14355
uniprot id: A0A1B1YWW4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1810504:PG2T RS07440
gene id: 1810504:PG2T_RS07440
uniprot id: A0A1B1YTL3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1810504:PG2T RS03925
gene id: 1810504:PG2T_RS03925
uniprot id: A0A1B1YXL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1810504:PG2T RS05490
gene id: 1810504:PG2T_RS05490
uniprot id: A0A1B1YSE8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1810504:PG2T RS08700
gene id: 1810504:PG2T_RS08700
uniprot id: A0A1B1YTX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1810504:PG2T RS12635
gene id: 1810504:PG2T_RS12635
uniprot id: A0A1B1YW41
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1810504:PG2T RS03285
gene id: 1810504:PG2T_RS03285
uniprot id: A0A1B1YRC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1810504:PG2T RS00600
gene id: 1810504:PG2T_RS00600
uniprot id: A0A1B1YPY3
names: Similarity
messages: Belongs to the glutamate synthase family.

1810504:PG2T RS09615
gene id: 1810504:PG2T_RS09615
uniprot id: A0A1B1YUJ1
names: Similarity
messages: Belongs to the peptidase C40 family.

1810504:PG2T RS01890
gene id: 1810504:PG2T_RS01890
uniprot id: A0A1B1YQK5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1810504:PG2T RS05545
gene id: 1810504:PG2T_RS05545
uniprot id: A0A1B1YSL1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS01340
gene id: 1810504:PG2T_RS01340
uniprot id: A0A1B1YQD1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1810504:PG2T RS00800
gene id: 1810504:PG2T_RS00800
uniprot id: A0A1B1YQ39
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1810504:PG2T RS02140
gene id: 1810504:PG2T_RS02140
uniprot id: A0A1B1YQT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1810504:PG2T RS12855
gene id: 1810504:PG2T_RS12855
uniprot id: A0A1B1YW81
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS07795
gene id: 1810504:PG2T_RS07795
uniprot id: A0A1B1YTR8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1810504:PG2T RS02075
gene id: 1810504:PG2T_RS02075
uniprot id: A0A1B1YQN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS13890
gene id: 1810504:PG2T_RS13890
uniprot id: A0A1B1YY12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1810504:PG2T RS12445
gene id: 1810504:PG2T_RS12445
uniprot id: A0A1B1YVI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1810504:PG2T RS14990
gene id: 1810504:PG2T_RS14990
uniprot id: A0A1B1YXJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1810504:PG2T RS10465
gene id: 1810504:PG2T_RS10465
uniprot id: A0A1B1YV13
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1810504:PG2T RS05650
gene id: 1810504:PG2T_RS05650
uniprot id: A0A1B1YSM9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1810504:PG2T RS02915
gene id: 1810504:PG2T_RS02915
uniprot id: A0A1B1YR39
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS14640
gene id: 1810504:PG2T_RS14640
uniprot id: A0A1B1YXE7
names: Similarity
messages: Belongs to the UPF0311 family.

1810504:PG2T RS12805
gene id: 1810504:PG2T_RS12805
uniprot id: A0A1B1YWA2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1810504:PG2T RS13750
gene id: 1810504:PG2T_RS13750
uniprot id: A0A1B1YX00
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1810504:PG2T RS12900
gene id: 1810504:PG2T_RS12900
uniprot id: A0A1B1YW03
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1810504:PG2T RS12880
gene id: 1810504:PG2T_RS12880
uniprot id: A0A1B1YW20
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1810504:PG2T RS00470
gene id: 1810504:PG2T_RS00470
uniprot id: A0A1B1YQ02
names: Similarity
messages: Belongs to the DapA family.

1810504:PG2T RS14950
gene id: 1810504:PG2T_RS14950
uniprot id: A0A1B1YXD9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1810504:PG2T RS03960
gene id: 1810504:PG2T_RS03960
uniprot id: A0A1B1YRX6
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1810504:PG2T RS05700
gene id: 1810504:PG2T_RS05700
uniprot id: A0A1B1YSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1810504:PG2T RS10560
gene id: 1810504:PG2T_RS10560
uniprot id: A0A1B1YVA3
names: Similarity
messages: Belongs to the RelE toxin family.

1810504:PG2T RS07410
gene id: 1810504:PG2T_RS07410
uniprot id: A0A1B1YTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1810504:PG2T RS05620
gene id: 1810504:PG2T_RS05620
uniprot id: A0A1B1YSU1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1810504:PG2T RS02990
gene id: 1810504:PG2T_RS02990
uniprot id: A0A1B1YR95
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS00425
gene id: 1810504:PG2T_RS00425
uniprot id: A0A1B1YPY9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1810504:PG2T RS04055
gene id: 1810504:PG2T_RS04055
uniprot id: A0A1B1YRM7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1810504:PG2T RS07525
gene id: 1810504:PG2T_RS07525
uniprot id: A0A1B1YTK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS01025
gene id: 1810504:PG2T_RS01025
uniprot id: A0A1B1YQ61
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1810504:PG2T RS13300
gene id: 1810504:PG2T_RS13300
uniprot id: A0A1B1YWK8
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1810504:PG2T RS00815
gene id: 1810504:PG2T_RS00815
uniprot id: A0A1B1YQ54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS08320
gene id: 1810504:PG2T_RS08320
uniprot id: A0A1B1YTX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1810504:PG2T RS13985
gene id: 1810504:PG2T_RS13985
uniprot id: A0A1B1YX39
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1810504:PG2T RS14075
gene id: 1810504:PG2T_RS14075
uniprot id: A0A1B1YWJ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS08655
gene id: 1810504:PG2T_RS08655
uniprot id: A0A1B1YTQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS04515
gene id: 1810504:PG2T_RS04515
uniprot id: A0A1B1YS68
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1810504:PG2T RS13475
gene id: 1810504:PG2T_RS13475
uniprot id: A0A1B1YW23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1810504:PG2T RS02875
gene id: 1810504:PG2T_RS02875
uniprot id: A0A1B1YR25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1810504:PG2T RS09530
gene id: 1810504:PG2T_RS09530
uniprot id: A0A1B1YUK6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1810504:PG2T RS12505
gene id: 1810504:PG2T_RS12505
uniprot id: A0A1B1YVV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1810504:PG2T RS09270
gene id: 1810504:PG2T_RS09270
uniprot id: A0A1B1YUE3
names: Similarity
messages: Belongs to the TrpF family.

1810504:PG2T RS11645
gene id: 1810504:PG2T_RS11645
uniprot id: A0A1B1YVA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1810504:PG2T RS13860
gene id: 1810504:PG2T_RS13860
uniprot id: A0A1B1YW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1810504:PG2T RS06020
gene id: 1810504:PG2T_RS06020
uniprot id: A0A1B1YSR6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS01550
gene id: 1810504:PG2T_RS01550
uniprot id: A0A1B1YQK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1810504:PG2T RS10230
gene id: 1810504:PG2T_RS10230
uniprot id: A0A1B1YUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1810504:PG2T RS09005
gene id: 1810504:PG2T_RS09005
uniprot id: A0A1B1YU90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1810504:PG2T RS09880
gene id: 1810504:PG2T_RS09880
uniprot id: A0A1B1YUN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1810504:PG2T RS04910
gene id: 1810504:PG2T_RS04910
uniprot id: A0A1B1YS61
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1810504:PG2T RS12595
gene id: 1810504:PG2T_RS12595
uniprot id: A0A1B1YW28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS08705
gene id: 1810504:PG2T_RS08705
uniprot id: A0A1B1YU40
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1810504:PG2T RS11780
gene id: 1810504:PG2T_RS11780
uniprot id: A0A1B1YV56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1810504:PG2T RS05175
gene id: 1810504:PG2T_RS05175
uniprot id: A0A1B1YS65
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS13830
gene id: 1810504:PG2T_RS13830
uniprot id: A0A1B1YWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1810504:PG2T RS03725
gene id: 1810504:PG2T_RS03725
uniprot id: A0A1B1YRG4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS10200
gene id: 1810504:PG2T_RS10200
uniprot id: A0A1B1YUW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1810504:PG2T RS15025
gene id: 1810504:PG2T_RS15025
uniprot id: A0A1B1YX79
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1810504:PG2T RS01565
gene id: 1810504:PG2T_RS01565
uniprot id: A0A1B1YQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1810504:PG2T RS01290
gene id: 1810504:PG2T_RS01290
uniprot id: A0A1B1YQB7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS14465
gene id: 1810504:PG2T_RS14465
uniprot id: A0A1B1YX08
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1810504:PG2T RS07160
gene id: 1810504:PG2T_RS07160
uniprot id: A0A1B1YT23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1810504:PG2T RS03255
gene id: 1810504:PG2T_RS03255
uniprot id: A0A1B1YRC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1810504:PG2T RS08685
gene id: 1810504:PG2T_RS08685
uniprot id: A0A1B1YTY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1810504:PG2T RS11455
gene id: 1810504:PG2T_RS11455
uniprot id: A0A1B1YVA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS14085
gene id: 1810504:PG2T_RS14085
uniprot id: A0A1B1YWQ2
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1810504:PG2T RS14900
gene id: 1810504:PG2T_RS14900
uniprot id: A0A1B1YXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1810504:PG2T RS08460
gene id: 1810504:PG2T_RS08460
uniprot id: A0A1B1YU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1810504:PG2T RS12785
gene id: 1810504:PG2T_RS12785
uniprot id: A0A1B1YVY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1810504:PG2T RS08895
gene id: 1810504:PG2T_RS08895
uniprot id: A0A1B1YUJ0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1810504:PG2T RS12270
gene id: 1810504:PG2T_RS12270
uniprot id: A0A1B1YW05
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS12775
gene id: 1810504:PG2T_RS12775
uniprot id: A0A1B1YWF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1810504:PG2T RS01110
gene id: 1810504:PG2T_RS01110
uniprot id: A0A1B1YQ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1810504:PG2T RS02445
gene id: 1810504:PG2T_RS02445
uniprot id: A0A1B1YQW0
names: Similarity
messages: Belongs to the pyruvate kinase family.

1810504:PG2T RS14535
gene id: 1810504:PG2T_RS14535
uniprot id: A0A1B1YWX5
names: Similarity
messages: Belongs to the ArsC family.

1810504:PG2T RS11205
gene id: 1810504:PG2T_RS11205
uniprot id: A0A1B1YVD1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1810504:PG2T RS10105
gene id: 1810504:PG2T_RS10105
uniprot id: A0A1B1YUF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1810504:PG2T RS09205
gene id: 1810504:PG2T_RS09205
uniprot id: A0A1B1YU63
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1810504:PG2T RS04565
gene id: 1810504:PG2T_RS04565
uniprot id: A0A1B1YRX8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1810504:PG2T RS14330
gene id: 1810504:PG2T_RS14330
uniprot id: A0A1B1YWM2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS00235
gene id: 1810504:PG2T_RS00235
uniprot id: A0A1B1YPV9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1810504:PG2T RS07105
gene id: 1810504:PG2T_RS07105
uniprot id: A0A1B1YTK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1810504:PG2T RS12025
gene id: 1810504:PG2T_RS12025
uniprot id: A0A1B1YVJ8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1810504:PG2T RS05400
gene id: 1810504:PG2T_RS05400
uniprot id: A0A1B1YSM8
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS00535
gene id: 1810504:PG2T_RS00535
uniprot id: A0A1B1YPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1810504:PG2T RS03710
gene id: 1810504:PG2T_RS03710
uniprot id: A0A1B1YRI7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS08940
gene id: 1810504:PG2T_RS08940
uniprot id: A0A1B1YTU8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1810504:PG2T RS08600
gene id: 1810504:PG2T_RS08600
uniprot id: A0A1B1YUE1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1810504:PG2T RS10370
gene id: 1810504:PG2T_RS10370
uniprot id: A0A1B1YUW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1810504:PG2T RS12980
gene id: 1810504:PG2T_RS12980
uniprot id: A0A1B1YVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1810504:PG2T RS08415
gene id: 1810504:PG2T_RS08415
uniprot id: A0A1B1YTK6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1810504:PG2T RS09365
gene id: 1810504:PG2T_RS09365
uniprot id: A0A1B1YU97
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1810504:PG2T RS10435
gene id: 1810504:PG2T_RS10435
uniprot id: A0A1B1YUR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1810504:PG2T RS03515
gene id: 1810504:PG2T_RS03515
uniprot id: A0A1B1YRC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1810504:PG2T RS10305
gene id: 1810504:PG2T_RS10305
uniprot id: A0A1B1YUP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1810504:PG2T RS10400
gene id: 1810504:PG2T_RS10400
uniprot id: A0A1B1YUY8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1810504:PG2T RS02085
gene id: 1810504:PG2T_RS02085
uniprot id: A0A1B1YXI4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1810504:PG2T RS14575
gene id: 1810504:PG2T_RS14575
uniprot id: A0A1B1YWS4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1810504:PG2T RS10190
gene id: 1810504:PG2T_RS10190
uniprot id: A0A1B1YUQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1810504:PG2T RS10715
gene id: 1810504:PG2T_RS10715
uniprot id: A0A1B1YV96
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1810504:PG2T RS14165
gene id: 1810504:PG2T_RS14165
uniprot id: A0A1B1YWX4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1810504:PG2T RS01470
gene id: 1810504:PG2T_RS01470
uniprot id: A0A1B1YQD2
names: Similarity
messages: Belongs to the DapA family.

1810504:PG2T RS06125
gene id: 1810504:PG2T_RS06125
uniprot id: A0A1B1YSU2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1810504:PG2T RS02955
gene id: 1810504:PG2T_RS02955
uniprot id: A0A1B1YR48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1810504:PG2T RS04650
gene id: 1810504:PG2T_RS04650
uniprot id: A0A1B1YS59
names: Similarity
messages: Belongs to the UPF0234 family.

1810504:PG2T RS01640
gene id: 1810504:PG2T_RS01640
uniprot id: A0A1B1YQG9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1810504:PG2T RS00435
gene id: 1810504:PG2T_RS00435
uniprot id: A0A1B1YPW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

1810504:PG2T RS14215
gene id: 1810504:PG2T_RS14215
uniprot id: A0A1B1YWJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1810504:PG2T RS03550
gene id: 1810504:PG2T_RS03550
uniprot id: A0A1B1YRF2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1810504:PG2T RS02180
gene id: 1810504:PG2T_RS02180
uniprot id: A0A1B1YQQ0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1810504:PG2T RS03500
gene id: 1810504:PG2T_RS03500
uniprot id: A0A1B1YRE6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1810504:PG2T RS04530
gene id: 1810504:PG2T_RS04530
uniprot id: A0A1B1YRV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1810504:PG2T RS03170
gene id: 1810504:PG2T_RS03170
uniprot id: A0A1B1YR86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1810504:PG2T RS10005
gene id: 1810504:PG2T_RS10005
uniprot id: A0A1B1YUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1810504:PG2T RS11105
gene id: 1810504:PG2T_RS11105
uniprot id: A0A1B1YV59
names: Similarity
messages: Belongs to the CFA/CMAS family.

1810504:PG2T RS05760
gene id: 1810504:PG2T_RS05760
uniprot id: A0A1B1YSQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1810504:PG2T RS04705
gene id: 1810504:PG2T_RS04705
uniprot id: A0A1B1YRW1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1810504:PG2T RS03310
gene id: 1810504:PG2T_RS03310
uniprot id: A0A1B1YRB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1810504:PG2T RS04805
gene id: 1810504:PG2T_RS04805
uniprot id: A0A1B1YRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1810504:PG2T RS08390
gene id: 1810504:PG2T_RS08390
uniprot id: A0A1B1YTU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1810504:PG2T RS10910
gene id: 1810504:PG2T_RS10910
uniprot id: A0A1B1YV47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1810504:PG2T RS03250
gene id: 1810504:PG2T_RS03250
uniprot id: A0A1B1YRG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1810504:PG2T RS07405
gene id: 1810504:PG2T_RS07405
uniprot id: A0A1B1YT37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1810504:PG2T RS02415
gene id: 1810504:PG2T_RS02415
uniprot id: A0A1B1YQT6
names: Similarity
messages: Belongs to the arginase family.

1810504:PG2T RS02260
gene id: 1810504:PG2T_RS02260
uniprot id: A0A1B1YQS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1810504:PG2T RS09820
gene id: 1810504:PG2T_RS09820
uniprot id: A0A1B1YUA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1810504:PG2T RS04410
gene id: 1810504:PG2T_RS04410
uniprot id: A0A1B1YS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS00560
gene id: 1810504:PG2T_RS00560
uniprot id: A0A1B1YPY2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1810504:PG2T RS04175
gene id: 1810504:PG2T_RS04175
uniprot id: A0A1B1YRQ4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1810504:PG2T RS02375
gene id: 1810504:PG2T_RS02375
uniprot id: A0A1B1YQY7
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS14495
gene id: 1810504:PG2T_RS14495
uniprot id: A0A1B1YWN6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1810504:PG2T RS14710
gene id: 1810504:PG2T_RS14710
uniprot id: A0A1B1YX99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1810504:PG2T RS05750
gene id: 1810504:PG2T_RS05750
uniprot id: A0A1B1YSS8
names: Similarity
messages: Belongs to the DapA family.

1810504:PG2T RS10870
gene id: 1810504:PG2T_RS10870
uniprot id: A0A1B1YUY5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1810504:PG2T RS05205
gene id: 1810504:PG2T_RS05205
uniprot id: A0A1B1YS14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS06050
gene id: 1810504:PG2T_RS06050
uniprot id: A0A1B1YSW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1810504:PG2T RS06060
gene id: 1810504:PG2T_RS06060
uniprot id: A0A1B1YT26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1810504:PG2T RS12475
gene id: 1810504:PG2T_RS12475
uniprot id: A0A1B1YVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1810504:PG2T RS09415
gene id: 1810504:PG2T_RS09415
uniprot id: A0A1B1YUA9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1810504:PG2T RS03360
gene id: 1810504:PG2T_RS03360
uniprot id: A0A1B1YRE2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS14065
gene id: 1810504:PG2T_RS14065
uniprot id: A0A1B1YWT9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1810504:PG2T RS05680
gene id: 1810504:PG2T_RS05680
uniprot id: A0A1B1YSE7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1810504:PG2T RS00950
gene id: 1810504:PG2T_RS00950
uniprot id: A0A1B1YQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1810504:PG2T RS03200
gene id: 1810504:PG2T_RS03200
uniprot id: A0A1B1YR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1810504:PG2T RS09830
gene id: 1810504:PG2T_RS09830
uniprot id: A0A1B1YUM7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1810504:PG2T RS01765
gene id: 1810504:PG2T_RS01765
uniprot id: A0A1B1YXF1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1810504:PG2T RS06085
gene id: 1810504:PG2T_RS06085
uniprot id: A0A1B1YSJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1810504:PG2T RS08675
gene id: 1810504:PG2T_RS08675
uniprot id: A0A1B1YUF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1810504:PG2T RS04585
gene id: 1810504:PG2T_RS04585
uniprot id: A0A1B1YRV0
names: Similarity
messages: Belongs to the UPF0434 family.

1810504:PG2T RS04795
gene id: 1810504:PG2T_RS04795
uniprot id: A0A1B1YRZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS07225
gene id: 1810504:PG2T_RS07225
uniprot id: A0A1B1YT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1810504:PG2T RS13085
gene id: 1810504:PG2T_RS13085
uniprot id: A0A1B1YWD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1810504:PG2T RS02500
gene id: 1810504:PG2T_RS02500
uniprot id: A0A1B1YXC4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1810504:PG2T RS14805
gene id: 1810504:PG2T_RS14805
uniprot id: A0A1B1YXH6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1810504:PG2T RS03260
gene id: 1810504:PG2T_RS03260
uniprot id: A0A1B1YRA0
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS14685
gene id: 1810504:PG2T_RS14685
uniprot id: A0A1B1YX03
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1810504:PG2T RS04375
gene id: 1810504:PG2T_RS04375
uniprot id: A0A1B1YRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1810504:PG2T RS03185
gene id: 1810504:PG2T_RS03185
uniprot id: A0A1B1YRB2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS02065
gene id: 1810504:PG2T_RS02065
uniprot id: A0A1B1YQU7
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1810504:PG2T RS04500
gene id: 1810504:PG2T_RS04500
uniprot id: A0A1B1YRW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1810504:PG2T RS03335
gene id: 1810504:PG2T_RS03335
uniprot id: A0A1B1YRA1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1810504:PG2T RS10885
gene id: 1810504:PG2T_RS10885
uniprot id: A0A1B1YVF6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1810504:PG2T RS05450
gene id: 1810504:PG2T_RS05450
uniprot id: A0A1B1YSI3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS02365
gene id: 1810504:PG2T_RS02365
uniprot id: A0A1B1YQT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1810504:PG2T RS02190
gene id: 1810504:PG2T_RS02190
uniprot id: A0A1B1YQT7
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS01985
gene id: 1810504:PG2T_RS01985
uniprot id: A0A1B1YQP6
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1810504:PG2T RS07845
gene id: 1810504:PG2T_RS07845
uniprot id: A0A1B1YU16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS10505
gene id: 1810504:PG2T_RS10505
uniprot id: A0A1B1YV92
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS05800
gene id: 1810504:PG2T_RS05800
uniprot id: A0A1B1YSN2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS13360
gene id: 1810504:PG2T_RS13360
uniprot id: A0A1B1YWH4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

1810504:PG2T RS05180
gene id: 1810504:PG2T_RS05180
uniprot id: A0A1B1YSE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1810504:PG2T RS13850
gene id: 1810504:PG2T_RS13850
uniprot id: A0A1B1YWQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1810504:PG2T RS12225
gene id: 1810504:PG2T_RS12225
uniprot id: A0A1B1YXZ1
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS04695
gene id: 1810504:PG2T_RS04695
uniprot id: A0A1B1YRY0
names: Similarity
messages: Belongs to the fabD family.

1810504:PG2T RS01910
gene id: 1810504:PG2T_RS01910
uniprot id: A0A1B1YQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1810504:PG2T RS06650
gene id: 1810504:PG2T_RS06650
uniprot id: A0A1B1YSP4
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1810504:PG2T RS11310
gene id: 1810504:PG2T_RS11310
uniprot id: A0A1B1YVF0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS14765
gene id: 1810504:PG2T_RS14765
uniprot id: A0A1B1YY05
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1810504:PG2T RS05070
gene id: 1810504:PG2T_RS05070
uniprot id: A0A1B1YS38
names: Subunit
messages: Monomer.

1810504:PG2T RS13865
gene id: 1810504:PG2T_RS13865
uniprot id: A0A1B1YWG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1810504:PG2T RS02765
gene id: 1810504:PG2T_RS02765
uniprot id: A0A1B1YR05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1810504:PG2T RS04450
gene id: 1810504:PG2T_RS04450
uniprot id: A0A1B1YRW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1810504:PG2T RS07040
gene id: 1810504:PG2T_RS07040
uniprot id: A0A1B1YT49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1810504:PG2T RS01555
gene id: 1810504:PG2T_RS01555
uniprot id: A0A1B1YQE7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS11855
gene id: 1810504:PG2T_RS11855
uniprot id: A0A1B1YVE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS12490
gene id: 1810504:PG2T_RS12490
uniprot id: A0A1B1YW08
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1810504:PG2T RS01125
gene id: 1810504:PG2T_RS01125
uniprot id: A0A1B1YQ79
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1810504:PG2T RS06935
gene id: 1810504:PG2T_RS06935
uniprot id: A0A1B1YT01
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS04505
gene id: 1810504:PG2T_RS04505
uniprot id: A0A1B1YRX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS10250
gene id: 1810504:PG2T_RS10250
uniprot id: A0A1B1YV57
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS12015
gene id: 1810504:PG2T_RS12015
uniprot id: A0A1B1YW04
names: Similarity
messages: Belongs to the PhzF family.

1810504:PG2T RS04495
gene id: 1810504:PG2T_RS04495
uniprot id: A0A1B1YS97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1810504:PG2T RS09845
gene id: 1810504:PG2T_RS09845
uniprot id: A0A1B1YUJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS04180
gene id: 1810504:PG2T_RS04180
uniprot id: A0A1B1YRP7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1810504:PG2T RS11625
gene id: 1810504:PG2T_RS11625
uniprot id: A0A1B1YV30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1810504:PG2T RS03420
gene id: 1810504:PG2T_RS03420
uniprot id: A0A1B1YRE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1810504:PG2T RS14605
gene id: 1810504:PG2T_RS14605
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS07445
gene id: 1810504:PG2T_RS07445
uniprot id: A0A1B1YT73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1810504:PG2T RS01570
gene id: 1810504:PG2T_RS01570
uniprot id: A0A1B1YQK6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1810504:PG2T RS13805
gene id: 1810504:PG2T_RS13805
uniprot id: A0A1B1YWK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1810504:PG2T RS02850
gene id: 1810504:PG2T_RS02850
uniprot id: A0A1B1YR94
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1810504:PG2T RS05855
gene id: 1810504:PG2T_RS05855
uniprot id: A0A1B1YSP5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1810504:PG2T RS01615
gene id: 1810504:PG2T_RS01615
uniprot id: A0A1B1YQG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1810504:PG2T RS01900
gene id: 1810504:PG2T_RS01900
uniprot id: A0A1B1YQN2
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1810504:PG2T RS04455
gene id: 1810504:PG2T_RS04455
uniprot id: A0A1B1YRU8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1810504:PG2T RS05465
gene id: 1810504:PG2T_RS05465
uniprot id: A0A1B1YS99
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1810504:PG2T RS11710
gene id: 1810504:PG2T_RS11710
uniprot id: A0A1B1YVH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1810504:PG2T RS02820
gene id: 1810504:PG2T_RS02820
uniprot id: A0A1B1YR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS08155
gene id: 1810504:PG2T_RS08155
uniprot id: A0A1B1YTX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1810504:PG2T RS08210
gene id: 1810504:PG2T_RS08210
uniprot id: A0A1B1YTK7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1810504:PG2T RS11300
gene id: 1810504:PG2T_RS11300
uniprot id: A0A1B1YV71
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS11650
gene id: 1810504:PG2T_RS11650
uniprot id: A0A1B1YVC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1810504:PG2T RS04875
gene id: 1810504:PG2T_RS04875
uniprot id: A0A1B1YS94
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1810504:PG2T RS12910
gene id: 1810504:PG2T_RS12910
uniprot id: A0A1B1YW87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS09360
gene id: 1810504:PG2T_RS09360
uniprot id: A0A1B1YUI0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1810504:PG2T RS09920
gene id: 1810504:PG2T_RS09920
uniprot id: A0A1B1YUS1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1810504:PG2T RS00195
gene id: 1810504:PG2T_RS00195
uniprot id: A0A1B1YPQ7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1810504:PG2T RS07990
gene id: 1810504:PG2T_RS07990
uniprot id: A0A1B1YTM1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1810504:PG2T RS15545
gene id: 1810504:PG2T_RS15545
uniprot id: A0A1B1YUU0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1810504:PG2T RS07695
gene id: 1810504:PG2T_RS07695
uniprot id: A0A1B1YTG7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1810504:PG2T RS06075
gene id: 1810504:PG2T_RS06075
uniprot id: A0A1B1YSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1810504:PG2T RS03555
gene id: 1810504:PG2T_RS03555
uniprot id: A0A1B1YRF9
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS02515
gene id: 1810504:PG2T_RS02515
uniprot id: A0A1B1YQY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1810504:PG2T RS00740
gene id: 1810504:PG2T_RS00740
uniprot id: A0A1B1YQ33
names: Similarity
messages: Belongs to the DapA family.

1810504:PG2T RS03830
gene id: 1810504:PG2T_RS03830
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS13335
gene id: 1810504:PG2T_RS13335
uniprot id: A0A1B1YW65
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1810504:PG2T RS04050
gene id: 1810504:PG2T_RS04050
uniprot id: A0A1B1YRQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1810504:PG2T RS07055
gene id: 1810504:PG2T_RS07055
uniprot id: A0A1B1YT24
names: Similarity
messages: Belongs to the TrpC family.

1810504:PG2T RS14450
gene id: 1810504:PG2T_RS14450
uniprot id: A0A1B1YWN5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1810504:PG2T RS02540
gene id: 1810504:PG2T_RS02540
uniprot id: A0A1B1YQW7
names: Similarity
messages: Belongs to the PhoH family.

1810504:PG2T RS08160
gene id: 1810504:PG2T_RS08160
uniprot id: A0A1B1YTQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1810504:PG2T RS09340
gene id: 1810504:PG2T_RS09340
uniprot id: A0A1B1YUR6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1810504:PG2T RS00420
gene id: 1810504:PG2T_RS00420
uniprot id: A0A1B1YPW2
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

1810504:PG2T RS07570
gene id: 1810504:PG2T_RS07570
uniprot id: A0A1B1YTN2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1810504:PG2T RS08635
gene id: 1810504:PG2T_RS08635
uniprot id: A0A1B1YTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1810504:PG2T RS13025
gene id: 1810504:PG2T_RS13025
uniprot id: A0A1B1YXV4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1810504:PG2T RS12500
gene id: 1810504:PG2T_RS12500
uniprot id: A0A1B1YVU9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1810504:PG2T RS10025
gene id: 1810504:PG2T_RS10025
uniprot id: A0A1B1YUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1810504:PG2T RS02185
gene id: 1810504:PG2T_RS02185
uniprot id: A0A1B1YQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1810504:PG2T RS14090
gene id: 1810504:PG2T_RS14090
uniprot id: A0A1B1YX59
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1810504:PG2T RS03865
gene id: 1810504:PG2T_RS03865
uniprot id: A0A1B1YRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1810504:PG2T RS05695
gene id: 1810504:PG2T_RS05695
uniprot id: A0A1B1YSS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1810504:PG2T RS12935
gene id: 1810504:PG2T_RS12935
uniprot id: A0A1B1YW36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1810504:PG2T RS15180
gene id: 1810504:PG2T_RS15180
uniprot id: A0A1B1YXI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1810504:PG2T RS08580
gene id: 1810504:PG2T_RS08580
uniprot id: A0A1B1YU18
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS10045
gene id: 1810504:PG2T_RS10045
uniprot id: A0A1B1YUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1810504:PG2T RS01730
gene id: 1810504:PG2T_RS01730
uniprot id: A0A1B1YQN5
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS04395
gene id: 1810504:PG2T_RS04395
uniprot id: A0A1B1YRU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS13290
gene id: 1810504:PG2T_RS13290
uniprot id: A0A1B1YW66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS01090
gene id: 1810504:PG2T_RS01090
uniprot id: A0A1B1YQ72
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1810504:PG2T RS09165
gene id: 1810504:PG2T_RS09165
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS00090
gene id: 1810504:PG2T_RS00090
uniprot id: A0A1B1YPP1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1810504:PG2T RS04435
gene id: 1810504:PG2T_RS04435
uniprot id: A0A1B1YRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1810504:PG2T RS07780
gene id: 1810504:PG2T_RS07780
uniprot id: A0A1B1YTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1810504:PG2T RS01410
gene id: 1810504:PG2T_RS01410
uniprot id: A0A1B1YQH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1810504:PG2T RS02950
gene id: 1810504:PG2T_RS02950
uniprot id: A0A1B1YXT3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1810504:PG2T RS07625
gene id: 1810504:PG2T_RS07625
uniprot id: A0A1B1YTH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1810504:PG2T RS09430
gene id: 1810504:PG2T_RS09430
uniprot id: A0A1B1YU95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1810504:PG2T RS01595
gene id: 1810504:PG2T_RS01595
uniprot id: A0A1B1YQI1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS08105
gene id: 1810504:PG2T_RS08105
uniprot id: A0A1B1YTN9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1810504:PG2T RS00305
gene id: 1810504:PG2T_RS00305
uniprot id: A0A1B1YPT8
names: Similarity
messages: Belongs to the NifX/NifY family.

1810504:PG2T RS14920
gene id: 1810504:PG2T_RS14920
uniprot id: A0A1B1YX35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS10995
gene id: 1810504:PG2T_RS10995
uniprot id: A0A1B1YUU7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS10205
gene id: 1810504:PG2T_RS10205
uniprot id: A0A1B1YUX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1810504:PG2T RS02880
gene id: 1810504:PG2T_RS02880
uniprot id: A0A1B1YR76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1810504:PG2T RS09940
gene id: 1810504:PG2T_RS09940
uniprot id: A0A1B1YUP7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1810504:PG2T RS12750
gene id: 1810504:PG2T_RS12750
uniprot id: A0A1B1YW54
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1810504:PG2T RS11110
gene id: 1810504:PG2T_RS11110
uniprot id: A0A1B1YV64
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

1810504:PG2T RS00240
gene id: 1810504:PG2T_RS00240
uniprot id: A0A1B1YPU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1810504:PG2T RS02230
gene id: 1810504:PG2T_RS02230
uniprot id: A0A1B1YQR9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1810504:PG2T RS12570
gene id: 1810504:PG2T_RS12570
uniprot id: A0A1B1YVT5
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS08230
gene id: 1810504:PG2T_RS08230
uniprot id: A0A1B1YTS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1810504:PG2T RS13470
gene id: 1810504:PG2T_RS13470
uniprot id: A0A1B1YWG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1810504:PG2T RS07290
gene id: 1810504:PG2T_RS07290
uniprot id: A0A1B1YXU8
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1810504:PG2T RS08055
gene id: 1810504:PG2T_RS08055
uniprot id: A0A1B1YTK9
names: Similarity
messages: Belongs to the UPF0758 family.

1810504:PG2T RS07550
gene id: 1810504:PG2T_RS07550
uniprot id: A0A1B1YTR7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1810504:PG2T RS07565
gene id: 1810504:PG2T_RS07565
uniprot id: A0A1B1YTG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1810504:PG2T RS14715
gene id: 1810504:PG2T_RS14715
uniprot id: A0A1B1YX56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1810504:PG2T RS08660
gene id: 1810504:PG2T_RS08660
uniprot id: A0A1B1YTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1810504:PG2T RS02460
gene id: 1810504:PG2T_RS02460
uniprot id: A0A1B1YR13
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS07645
gene id: 1810504:PG2T_RS07645
uniprot id: A0A1B1YT81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1810504:PG2T RS05860
gene id: 1810504:PG2T_RS05860
uniprot id: A0A1B1YSP3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1810504:PG2T RS02670
gene id: 1810504:PG2T_RS02670
uniprot id: A0A1B1YQY2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS03010
gene id: 1810504:PG2T_RS03010
uniprot id: A0A1B1YR78
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1810504:PG2T RS00170
gene id: 1810504:PG2T_RS00170
uniprot id: A0A1B1YPU0
names: Similarity
messages: Belongs to the NifZ family.

1810504:PG2T RS00065
gene id: 1810504:PG2T_RS00065
uniprot id: A0A1B1YPT3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1810504:PG2T RS13190
gene id: 1810504:PG2T_RS13190
uniprot id: A0A1B1YWC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1810504:PG2T RS03130
gene id: 1810504:PG2T_RS03130
uniprot id: A0A1B1YRA2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1810504:PG2T RS00350
gene id: 1810504:PG2T_RS00350
uniprot id: A0A1B1YPX3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1810504:PG2T RS08120
gene id: 1810504:PG2T_RS08120
uniprot id: A0A1B1YTF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1810504:PG2T RS03900
gene id: 1810504:PG2T_RS03900
uniprot id: A0A1B1YXE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1810504:PG2T RS13240
gene id: 1810504:PG2T_RS13240
uniprot id: A0A1B1YWJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1810504:PG2T RS02095
gene id: 1810504:PG2T_RS02095
uniprot id: A0A1B1YQT1
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS12840
gene id: 1810504:PG2T_RS12840
uniprot id: A0A1B1YVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1810504:PG2T RS03975
gene id: 1810504:PG2T_RS03975
uniprot id: A0A1B1YRL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS02505
gene id: 1810504:PG2T_RS02505
uniprot id: A0A1B1YXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1810504:PG2T RS01435
gene id: 1810504:PG2T_RS01435
uniprot id: A0A1B1YQF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS09650
gene id: 1810504:PG2T_RS09650
uniprot id: A0A1B1YUM0
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1810504:PG2T RS10460
gene id: 1810504:PG2T_RS10460
uniprot id: A0A1B1YUZ7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1810504:PG2T RS11735
gene id: 1810504:PG2T_RS11735
uniprot id: A0A1B1YVG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1810504:PG2T RS13880
gene id: 1810504:PG2T_RS13880
uniprot id: A0A1B1YWE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1810504:PG2T RS04780
gene id: 1810504:PG2T_RS04780
uniprot id: A0A1B1YS67
names: Similarity
messages: Belongs to the YciI family.

1810504:PG2T RS02630
gene id: 1810504:PG2T_RS02630
uniprot id: A0A1B1YR45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1810504:PG2T RS10685
gene id: 1810504:PG2T_RS10685
uniprot id: A0A1B1YVC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1810504:PG2T RS08175
gene id: 1810504:PG2T_RS08175
uniprot id: A0A1B1YTV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1810504:PG2T RS04285
gene id: 1810504:PG2T_RS04285
uniprot id: A0A1B1YRS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1810504:PG2T RS03125
gene id: 1810504:PG2T_RS03125
uniprot id: A0A1B1YRE4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1810504:PG2T RS10680
gene id: 1810504:PG2T_RS10680
uniprot id: A0A1B1YV14
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1810504:PG2T RS05195
gene id: 1810504:PG2T_RS05195
uniprot id: A0A1B1YS54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS07790
gene id: 1810504:PG2T_RS07790
uniprot id: A0A1B1YTJ9
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1810504:PG2T RS13015
gene id: 1810504:PG2T_RS13015
uniprot id: A0A1B1YW85
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1810504:PG2T RS09540
gene id: 1810504:PG2T_RS09540
uniprot id: A0A1B1YUJ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1810504:PG2T RS13030
gene id: 1810504:PG2T_RS13030
uniprot id: A0A1B1YWB4
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS12495
gene id: 1810504:PG2T_RS12495
uniprot id: A0A1B1YVJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1810504:PG2T RS12515
gene id: 1810504:PG2T_RS12515
uniprot id: A0A1B1YVS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1810504:PG2T RS12620
gene id: 1810504:PG2T_RS12620
uniprot id: A0A1B1YVU3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1810504:PG2T RS05105
gene id: 1810504:PG2T_RS05105
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS11960
gene id: 1810504:PG2T_RS11960
uniprot id: A0A1B1YVZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1810504:PG2T RS02700
gene id: 1810504:PG2T_RS02700
uniprot id: A0A1B1YQZ9
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1810504:PG2T RS09160
gene id: 1810504:PG2T_RS09160
uniprot id: A0A1B1YTX9
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1810504:PG2T RS02250
gene id: 1810504:PG2T_RS02250
uniprot id: A0A1B1YQR1
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1810504:PG2T RS12320
gene id: 1810504:PG2T_RS12320
uniprot id: A0A1B1YW17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1810504:PG2T RS04640
gene id: 1810504:PG2T_RS04640
uniprot id: A0A1B1YS88
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1810504:PG2T RS12440
gene id: 1810504:PG2T_RS12440
uniprot id: A0A1B1YVZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1810504:PG2T RS05785
gene id: 1810504:PG2T_RS05785
uniprot id: A0A1B1YSX2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1810504:PG2T RS00120
gene id: 1810504:PG2T_RS00120
uniprot id: A0A1B1YPU3
names: Similarity
messages: Belongs to the HesB/IscA family.

1810504:PG2T RS08110
gene id: 1810504:PG2T_RS08110
uniprot id: A0A1B1YTV0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1810504:PG2T RS06895
gene id: 1810504:PG2T_RS06895
uniprot id: A0A1B1YSY6
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1810504:PG2T RS12395
gene id: 1810504:PG2T_RS12395
uniprot id: A0A1B1YVT8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1810504:PG2T RS03880
gene id: 1810504:PG2T_RS03880
uniprot id: A0A1B1YRJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1810504:PG2T RS00915
gene id: 1810504:PG2T_RS00915
uniprot id: A0A1B1YQ60
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS12790
gene id: 1810504:PG2T_RS12790
uniprot id: A0A1B1YW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS09265
gene id: 1810504:PG2T_RS09265
uniprot id: A0A1B1YU77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1810504:PG2T RS04855
gene id: 1810504:PG2T_RS04855
uniprot id: A0A1B1YS53
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1810504:PG2T RS12760
gene id: 1810504:PG2T_RS12760
uniprot id: A0A1B1YVP7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1810504:PG2T RS12275
gene id: 1810504:PG2T_RS12275
uniprot id: A0A1B1YVW4
names: PTM
messages: Binds 1 heme group per subunit.

1810504:PG2T RS05810
gene id: 1810504:PG2T_RS05810
uniprot id: A0A1B1YST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1810504:PG2T RS00940
gene id: 1810504:PG2T_RS00940
uniprot id: A0A1B1YQ43
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1810504:PG2T RS10865
gene id: 1810504:PG2T_RS10865
uniprot id: A0A1B1YUT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1810504:PG2T RS09950
gene id: 1810504:PG2T_RS09950
uniprot id: A0A1B1YXW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1810504:PG2T RS00755
gene id: 1810504:PG2T_RS00755
uniprot id: A0A1B1YQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1810504:PG2T RS04350
gene id: 1810504:PG2T_RS04350
uniprot id: A0A1B1YRS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1810504:PG2T RS05840
gene id: 1810504:PG2T_RS05840
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS02760
gene id: 1810504:PG2T_RS02760
uniprot id: A0A1B1YR19
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1810504:PG2T RS10035
gene id: 1810504:PG2T_RS10035
uniprot id: A0A1B1YUT1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1810504:PG2T RS06790
gene id: 1810504:PG2T_RS06790
uniprot id: A0A1B1YT04
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS12725
gene id: 1810504:PG2T_RS12725
uniprot id: A0A1B1YVW3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1810504:PG2T RS11655
gene id: 1810504:PG2T_RS11655
uniprot id: A0A1B1YVG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1810504:PG2T RS12325
gene id: 1810504:PG2T_RS12325
uniprot id: A0A1B1YVX5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1810504:PG2T RS14095
gene id: 1810504:PG2T_RS14095
uniprot id: A0A1B1YWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1810504:PG2T RS14470
gene id: 1810504:PG2T_RS14470
uniprot id: A0A1B1YWY4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1810504:PG2T RS02170
gene id: 1810504:PG2T_RS02170
uniprot id: A0A1B1YQT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1810504:PG2T RS05675
gene id: 1810504:PG2T_RS05675
uniprot id: A0A1B1YSV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1810504:PG2T RS06770
gene id: 1810504:PG2T_RS06770
uniprot id: A0A1B1YTB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1810504:PG2T RS13915
gene id: 1810504:PG2T_RS13915
uniprot id: A0A1B1YWB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1810504:PG2T RS01895
gene id: 1810504:PG2T_RS01895
uniprot id: A0A1B1YQP2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1810504:PG2T RS02750
gene id: 1810504:PG2T_RS02750
uniprot id: A0A1B1YR32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS01580
gene id: 1810504:PG2T_RS01580
uniprot id: A0A1B1YQH4
names: Similarity
messages: Belongs to the YkuD family.

1810504:PG2T RS03545
gene id: 1810504:PG2T_RS03545
uniprot id: A0A1B1YRH0
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1810504:PG2T RS14335
gene id: 1810504:PG2T_RS14335
uniprot id: A0A1B1YX06
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1810504:PG2T RS02160
gene id: 1810504:PG2T_RS02160
uniprot id: A0A1B1YQU9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS08245
gene id: 1810504:PG2T_RS08245
uniprot id: A0A1B1YTW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1810504:PG2T RS08560
gene id: 1810504:PG2T_RS08560
uniprot id: A0A1B1YTX0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS00980
gene id: 1810504:PG2T_RS00980
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS14760
gene id: 1810504:PG2T_RS14760
uniprot id: A0A1B1YX86
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1810504:PG2T RS01725
gene id: 1810504:PG2T_RS01725
uniprot id: A0A1B1YQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1810504:PG2T RS02490
gene id: 1810504:PG2T_RS02490
uniprot id: A0A1B1YQV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1810504:PG2T RS03265
gene id: 1810504:PG2T_RS03265
uniprot id: A0A1B1YRA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1810504:PG2T RS09405
gene id: 1810504:PG2T_RS09405
uniprot id: A0A1B1YUH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1810504:PG2T RS10445
gene id: 1810504:PG2T_RS10445
uniprot id: A0A1B1YV85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1810504:PG2T RS13730
gene id: 1810504:PG2T_RS13730
uniprot id: A0A1B1YWK4
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS04390
gene id: 1810504:PG2T_RS04390
uniprot id: A0A1B1YRT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1810504:PG2T RS13670
gene id: 1810504:PG2T_RS13670
uniprot id: A0A1B1YXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1810504:PG2T RS05510
gene id: 1810504:PG2T_RS05510
uniprot id: A0A1B1YSC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1810504:PG2T RS02975
gene id: 1810504:PG2T_RS02975
uniprot id: A0A1B1YR50
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS04295
gene id: 1810504:PG2T_RS04295
uniprot id: A0A1B1YS32
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1810504:PG2T RS11445
gene id: 1810504:PG2T_RS11445
uniprot id: A0A1B1YVP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1810504:PG2T RS00115
gene id: 1810504:PG2T_RS00115
uniprot id: A0A1B1YPT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1810504:PG2T RS08260
gene id: 1810504:PG2T_RS08260
uniprot id: A0A1B1YTP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1810504:PG2T RS09260
gene id: 1810504:PG2T_RS09260
uniprot id: A0A1B1YUF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1810504:PG2T RS09935
gene id: 1810504:PG2T_RS09935
uniprot id: A0A1B1YUI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1810504:PG2T RS13075
gene id: 1810504:PG2T_RS13075
uniprot id: A0A1B1YW88
names: Similarity
messages: Belongs to the TPP enzyme family.

1810504:PG2T RS08550
gene id: 1810504:PG2T_RS08550
uniprot id: A0A1B1YUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1810504:PG2T RS02610
gene id: 1810504:PG2T_RS02610
uniprot id: A0A1B1YQX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1810504:PG2T RS14360
gene id: 1810504:PG2T_RS14360
uniprot id: A0A1B1YWP1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS11795
gene id: 1810504:PG2T_RS11795
uniprot id: A0A1B1YVW6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1810504:PG2T RS11415
gene id: 1810504:PG2T_RS11415
uniprot id: A0A1B1YVH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1810504:PG2T RS06585
gene id: 1810504:PG2T_RS06585
uniprot id: A0A1B1YT77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1810504:PG2T RS07770
gene id: 1810504:PG2T_RS07770
uniprot id: A0A1B1YU06
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1810504:PG2T RS01865
gene id: 1810504:PG2T_RS01865
uniprot id: A0A1B1YQJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1810504:PG2T RS10860
gene id: 1810504:PG2T_RS10860
uniprot id: A0A1B1YV53
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1810504:PG2T RS12465
gene id: 1810504:PG2T_RS12465
uniprot id: A0A1B1YVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1810504:PG2T RS12710
gene id: 1810504:PG2T_RS12710
uniprot id: A0A1B1YVZ3
names: Similarity
messages: Belongs to the XFP family.

1810504:PG2T RS10315
gene id: 1810504:PG2T_RS10315
uniprot id: A0A1B1YV67
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1810504:PG2T RS05875
gene id: 1810504:PG2T_RS05875
uniprot id: A0A1B1YST2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1810504:PG2T RS12470
gene id: 1810504:PG2T_RS12470
uniprot id: A0A1B1YVS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1810504:PG2T RS06965
gene id: 1810504:PG2T_RS06965
uniprot id: A0A1B1YTB3
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS02650
gene id: 1810504:PG2T_RS02650
uniprot id: A0A1B1YQY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1810504:PG2T RS13820
gene id: 1810504:PG2T_RS13820
uniprot id: A0A1B1YX09
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1810504:PG2T RS08570
gene id: 1810504:PG2T_RS08570
uniprot id: A0A1B1YU37
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1810504:PG2T RS06775
gene id: 1810504:PG2T_RS06775
uniprot id: A0A1B1YSX0
names: Similarity
messages: Belongs to the XFP family.

1810504:PG2T RS12925
gene id: 1810504:PG2T_RS12925
uniprot id: A0A1B1YVS7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1810504:PG2T RS01020
gene id: 1810504:PG2T_RS01020
uniprot id: A0A1B1YQ87
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1810504:PG2T RS09775
gene id: 1810504:PG2T_RS09775
uniprot id: A0A1B1YUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS03295
gene id: 1810504:PG2T_RS03295
uniprot id: A0A1B1YRD2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1810504:PG2T RS13195
gene id: 1810504:PG2T_RS13195
uniprot id: A0A1B1YVX6
names: Similarity
messages: Belongs to the peptidase M16 family.

1810504:PG2T RS09640
gene id: 1810504:PG2T_RS09640
uniprot id: A0A1B1YUM6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS03070
gene id: 1810504:PG2T_RS03070
uniprot id: A0A1B1YRD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1810504:PG2T RS12080
gene id: 1810504:PG2T_RS12080
uniprot id: A0A1B1YVK5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1810504:PG2T RS07520
gene id: 1810504:PG2T_RS07520
uniprot id: A0A1B1YT83
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS04470
gene id: 1810504:PG2T_RS04470
uniprot id: A0A1B1YS33
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1810504:PG2T RS13480
gene id: 1810504:PG2T_RS13480
uniprot id: A0A1B1YWB0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1810504:PG2T RS06970
gene id: 1810504:PG2T_RS06970
uniprot id: A0A1B1YSW6
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS10000
gene id: 1810504:PG2T_RS10000
uniprot id: A0A1B1YUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1810504:PG2T RS11895
gene id: 1810504:PG2T_RS11895
uniprot id: A0A1B1YVK6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1810504:PG2T RS14030
gene id: 1810504:PG2T_RS14030
uniprot id: A0A1B1YWI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS13080
gene id: 1810504:PG2T_RS13080
uniprot id: A0A1B1YWG7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1810504:PG2T RS12135
gene id: 1810504:PG2T_RS12135
uniprot id: A0A1B1YVJ9
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS14060
gene id: 1810504:PG2T_RS14060
uniprot id: A0A1B1YWY9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1810504:PG2T RS14365
gene id: 1810504:PG2T_RS14365
uniprot id: A0A1B1YWU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1810504:PG2T RS03705
gene id: 1810504:PG2T_RS03705
uniprot id: A0A1B1YRH5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1810504:PG2T RS08820
gene id: 1810504:PG2T_RS08820
uniprot id: A0A1B1YTT1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1810504:PG2T RS05580
gene id: 1810504:PG2T_RS05580
uniprot id: A0A1B1YSK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1810504:PG2T RS05720
gene id: 1810504:PG2T_RS05720
uniprot id: A0A1B1YSP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1810504:PG2T RS12265
gene id: 1810504:PG2T_RS12265
uniprot id: A0A1B1YVW9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1810504:PG2T RS00520
gene id: 1810504:PG2T_RS00520
uniprot id: A0A1B1YQ16
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1810504:PG2T RS10610
gene id: 1810504:PG2T_RS10610
uniprot id: A0A1B1YUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS13440
gene id: 1810504:PG2T_RS13440
uniprot id: A0A1B1YW72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1810504:PG2T RS13465
gene id: 1810504:PG2T_RS13465
uniprot id: A0A1B1YWJ2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1810504:PG2T RS01105
gene id: 1810504:PG2T_RS01105
uniprot id: A0A1B1YQB4
names: Similarity
messages: Belongs to the MotB family.

1810504:PG2T RS04340
gene id: 1810504:PG2T_RS04340
uniprot id: A0A1B1YRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1810504:PG2T RS01560
gene id: 1810504:PG2T_RS01560
uniprot id: A0A1B1YQG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1810504:PG2T RS12250
gene id: 1810504:PG2T_RS12250
uniprot id: A0A1B1YVL9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1810504:PG2T RS01600
gene id: 1810504:PG2T_RS01600
uniprot id: A0A1B1YQK7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1810504:PG2T RS09645
gene id: 1810504:PG2T_RS09645
uniprot id: A0A1B1YUE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1810504:PG2T RS13285
gene id: 1810504:PG2T_RS13285
uniprot id: A0A1B1YW59
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1810504:PG2T RS14705
gene id: 1810504:PG2T_RS14705
uniprot id: A0A1B1YX78
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1810504:PG2T RS11755
gene id: 1810504:PG2T_RS11755
uniprot id: A0A1B1YVE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1810504:PG2T RS07835
gene id: 1810504:PG2T_RS07835
uniprot id: A0A1B1YTH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1810504:PG2T RS11430
gene id: 1810504:PG2T_RS11430
uniprot id: A0A1B1YV09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1810504:PG2T RS04360
gene id: 1810504:PG2T_RS04360
uniprot id: A0A1B1YRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1810504:PG2T RS06025
gene id: 1810504:PG2T_RS06025
uniprot id: A0A1B1YSX4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1810504:PG2T RS09730
gene id: 1810504:PG2T_RS09730
uniprot id: A0A1B1YUA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1810504:PG2T RS05525
gene id: 1810504:PG2T_RS05525
uniprot id: A0A1B1YSP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1810504:PG2T RS14600
gene id: 1810504:PG2T_RS14600
uniprot id: A0A1B1YSS1
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1810504:PG2T RS01465
gene id: 1810504:PG2T_RS01465
uniprot id: A0A1B1YQI4
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS02855
gene id: 1810504:PG2T_RS02855
uniprot id: A0A1B1YR52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1810504:PG2T RS13835
gene id: 1810504:PG2T_RS13835
uniprot id: A0A1B1YWR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1810504:PG2T RS10725
gene id: 1810504:PG2T_RS10725
uniprot id: A0A1B1YUR5
names: Similarity
messages: Belongs to the ModE family.

1810504:PG2T RS05690
gene id: 1810504:PG2T_RS05690
uniprot id: A0A1B1YSG0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1810504:PG2T RS08310
gene id: 1810504:PG2T_RS08310
uniprot id: A0A1B1YTI8
names: Similarity
messages: Belongs to the UPF0235 family.

1810504:PG2T RS14200
gene id: 1810504:PG2T_RS14200
uniprot id: A0A1B1YX76
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1810504:PG2T RS11410
gene id: 1810504:PG2T_RS11410
uniprot id: A0A1B1YVC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1810504:PG2T RS02130
gene id: 1810504:PG2T_RS02130
uniprot id: A0A1B1YQN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1810504:PG2T RS04510
gene id: 1810504:PG2T_RS04510
uniprot id: A0A1B1YRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS04260
gene id: 1810504:PG2T_RS04260
uniprot id: A0A1B1YRT7
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS02450
gene id: 1810504:PG2T_RS02450
uniprot id: A0A1B1YX57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1810504:PG2T RS10155
gene id: 1810504:PG2T_RS10155
uniprot id: A0A1B1YUG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1810504:PG2T RS00505
gene id: 1810504:PG2T_RS00505
uniprot id: A0A1B1YX31
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1810504:PG2T RS13740
gene id: 1810504:PG2T_RS13740
uniprot id: A0A1B1YWE6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1810504:PG2T RS15000
gene id: 1810504:PG2T_RS15000
uniprot id: A0A1B1YWX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1810504:PG2T RS04590
gene id: 1810504:PG2T_RS04590
uniprot id: A0A1B1YS47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1810504:PG2T RS00880
gene id: 1810504:PG2T_RS00880
uniprot id: A0A1B1YQ46
names: Subcellular Location Annotation
messages: Mitochondrion

1810504:PG2T RS01060
gene id: 1810504:PG2T_RS01060
uniprot id: A0A1B1YQ84
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS08965
gene id: 1810504:PG2T_RS08965
uniprot id: A0A1B1YU42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1810504:PG2T RS00145
gene id: 1810504:PG2T_RS00145
uniprot id: A0A1B1YPU1
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

1810504:PG2T RS12905
gene id: 1810504:PG2T_RS12905
uniprot id: A0A1B1YW45
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1810504:PG2T RS11955
gene id: 1810504:PG2T_RS11955
uniprot id: A0A1B1YVL5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1810504:PG2T RS08150
gene id: 1810504:PG2T_RS08150
uniprot id: A0A1B1YTR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1810504:PG2T RS12835
gene id: 1810504:PG2T_RS12835
uniprot id: A0A1B1YWG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1810504:PG2T RS11200
gene id: 1810504:PG2T_RS11200
uniprot id: A0A1B1YV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS03370
gene id: 1810504:PG2T_RS03370
uniprot id: A0A1B1YRC2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1810504:PG2T RS05495
gene id: 1810504:PG2T_RS05495
uniprot id: A0A1B1YSS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1810504:PG2T RS13095
gene id: 1810504:PG2T_RS13095
uniprot id: A0A1B1YVV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1810504:PG2T RS04895
gene id: 1810504:PG2T_RS04895
uniprot id: A0A1B1YS15
names: Similarity
messages: Belongs to the peptidase S33 family.

1810504:PG2T RS07870
gene id: 1810504:PG2T_RS07870
uniprot id: A0A1B1YTS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1810504:PG2T RS06565
gene id: 1810504:PG2T_RS06565
uniprot id: A0A1B1YST6
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS10730
gene id: 1810504:PG2T_RS10730
uniprot id: A0A1B1YUW8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1810504:PG2T RS04100
gene id: 1810504:PG2T_RS04100
uniprot id: A0A1B1YRV5
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS07455
gene id: 1810504:PG2T_RS07455
uniprot id: A0A1B1YTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1810504:PG2T RS07250
gene id: 1810504:PG2T_RS07250
uniprot id: A0A1B1YTL7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1810504:PG2T RS12090
gene id: 1810504:PG2T_RS12090
uniprot id: A0A1B1YVU1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1810504:PG2T RS02825
gene id: 1810504:PG2T_RS02825
uniprot id: A0A1B1YR67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1810504:PG2T RS10010
gene id: 1810504:PG2T_RS10010
uniprot id: A0A1B1YUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1810504:PG2T RS12285
gene id: 1810504:PG2T_RS12285
uniprot id: A0A1B1YVR1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1810504:PG2T RS13495
gene id: 1810504:PG2T_RS13495
uniprot id: A0A1B1YW80
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1810504:PG2T RS11770
gene id: 1810504:PG2T_RS11770
uniprot id: A0A1B1YVR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1810504:PG2T RS12955
gene id: 1810504:PG2T_RS12955
uniprot id: A0A1B1YY03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1810504:PG2T RS11630
gene id: 1810504:PG2T_RS11630
uniprot id: A0A1B1YVE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1810504:PG2T RS01220
gene id: 1810504:PG2T_RS01220
uniprot id: A0A1B1YQA2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1810504:PG2T RS12940
gene id: 1810504:PG2T_RS12940
uniprot id: A0A1B1YWL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1810504:PG2T RS07940
gene id: 1810504:PG2T_RS07940
uniprot id: A0A1B1YTL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1810504:PG2T RS11350
gene id: 1810504:PG2T_RS11350
uniprot id: A0A1B1YV58
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1810504:PG2T RS11730
gene id: 1810504:PG2T_RS11730
uniprot id: A0A1B1YV44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1810504:PG2T RS02280
gene id: 1810504:PG2T_RS02280
uniprot id: A0A1B1YQS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1810504:PG2T RS11400
gene id: 1810504:PG2T_RS11400
uniprot id: A0A1B1YV66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1810504:PG2T RS10355
gene id: 1810504:PG2T_RS10355
uniprot id: A0A1B1YUY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1810504:PG2T RS08325
gene id: 1810504:PG2T_RS08325
uniprot id: A0A1B1YU91
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1810504:PG2T RS04655
gene id: 1810504:PG2T_RS04655
uniprot id: A0A1B1YRV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1810504:PG2T RS11885
gene id: 1810504:PG2T_RS11885
uniprot id: A0A1B1YV76
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1810504:PG2T RS11130
gene id: 1810504:PG2T_RS11130
uniprot id: A0A1B1YV79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1810504:PG2T RS12715
gene id: 1810504:PG2T_RS12715
uniprot id: A0A1B1YVZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1810504:PG2T RS11840
gene id: 1810504:PG2T_RS11840
uniprot id: A0A1B1YVI2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1810504:PG2T RS08650
gene id: 1810504:PG2T_RS08650
uniprot id: A0A1B1YU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1810504:PG2T RS11665
gene id: 1810504:PG2T_RS11665
uniprot id: A0A1B1YVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1810504:PG2T RS03275
gene id: 1810504:PG2T_RS03275
uniprot id: A0A1B1YRE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1810504:PG2T RS11075
gene id: 1810504:PG2T_RS11075
uniprot id: A0A1B1YV35
names: Similarity
messages: Belongs to the glutamate synthase family.

1810504:PG2T RS05905
gene id: 1810504:PG2T_RS05905
uniprot id: A0A1B1YSQ5
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1810504:PG2T RS07660
gene id: 1810504:PG2T_RS07660
uniprot id: A0A1B1YTM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1810504:PG2T RS03455
gene id: 1810504:PG2T_RS03455
uniprot id: A0A1B1YRM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1810504:PG2T RS05455
gene id: 1810504:PG2T_RS05455
uniprot id: A0A1B1YSC1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1810504:PG2T RS08770
gene id: 1810504:PG2T_RS08770
uniprot id: A0A1B1YU51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1810504:PG2T RS04540
gene id: 1810504:PG2T_RS04540
uniprot id: A0A1B1YRZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1810504:PG2T RS08885
gene id: 1810504:PG2T_RS08885
uniprot id: A0A1B1YTZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1810504:PG2T RS13610
gene id: 1810504:PG2T_RS13610
uniprot id: A0A1B1YWR7
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1810504:PG2T RS01375
gene id: 1810504:PG2T_RS01375
uniprot id: A0A1B1YQC2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1810504:PG2T RS06120
gene id: 1810504:PG2T_RS06120
uniprot id: A0A1B1YST4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1810504:PG2T RS06055
gene id: 1810504:PG2T_RS06055
uniprot id: A0A1B1YXT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1810504:PG2T RS09370
gene id: 1810504:PG2T_RS09370
uniprot id: A0A1B1YUG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1810504:PG2T RS05520
gene id: 1810504:PG2T_RS05520
uniprot id: A0A1B1YSD2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1810504:PG2T RS05365
gene id: 1810504:PG2T_RS05365
uniprot id: A0A1B1YS35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1810504:PG2T RS00110
gene id: 1810504:PG2T_RS00110
uniprot id: A0A1B1YPP4
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1810504:PG2T RS04675
gene id: 1810504:PG2T_RS04675
uniprot id: A0A1B1YRZ1
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1810504:PG2T RS08855
gene id: 1810504:PG2T_RS08855
uniprot id: A0A1B1YU88
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1810504:PG2T RS08945
gene id: 1810504:PG2T_RS08945
uniprot id: A0A1B1YU04
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1810504:PG2T RS11715
gene id: 1810504:PG2T_RS11715
uniprot id: A0A1B1YVM3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1810504:PG2T RS10165
gene id: 1810504:PG2T_RS10165
uniprot id: A0A1B1YUT6
names: Similarity
messages: Belongs to the peptidase S16 family.

1810504:PG2T RS13045
gene id: 1810504:PG2T_RS13045
uniprot id: A0A1B1YVU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1810504:PG2T RS06480
gene id: 1810504:PG2T_RS06480
uniprot id: A0A1B1YT56
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1810504:PG2T RS01120
gene id: 1810504:PG2T_RS01120
uniprot id: A0A1B1YQ91
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1810504:PG2T RS08140
gene id: 1810504:PG2T_RS08140
uniprot id: A0A1B1YTJ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1810504:PG2T RS14815
gene id: 1810504:PG2T_RS14815
uniprot id: A0A1B1YWV7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1810504:PG2T RS08130
gene id: 1810504:PG2T_RS08130
uniprot id: A0A1B1YTU7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1810504:PG2T RS12735
gene id: 1810504:PG2T_RS12735
uniprot id: A0A1B1YW16
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1810504:PG2T RS11690
gene id: 1810504:PG2T_RS11690
uniprot id: A0A1B1YVG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1810504:PG2T RS00465
gene id: 1810504:PG2T_RS00465
uniprot id: A0A1B1YPZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1810504:PG2T RS11045
gene id: 1810504:PG2T_RS11045
uniprot id: A0A1B1YV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1810504:PG2T RS04600
gene id: 1810504:PG2T_RS04600
uniprot id: A0A1B1YRV7
names: Subcellular Location Annotation
messages: Membrane

1810504:PG2T RS09685
gene id: 1810504:PG2T_RS09685
uniprot id: A0A1B1YUM4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1810504:PG2T RS00415
gene id: 1810504:PG2T_RS00415
uniprot id: A0A1B1YPW0
names: Function
messages: Could be a 3Fe-4S cluster-containing protein.

1810504:PG2T RS04720
gene id: 1810504:PG2T_RS04720
uniprot id: A0A1B1YSE4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1810504:PG2T RS14935
gene id: 1810504:PG2T_RS14935
uniprot id: A0A1B1YWW7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1810504:PG2T RS08485
gene id: 1810504:PG2T_RS08485
uniprot id: A0A1B1YXN6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1810504:PG2T RS07035
gene id: 1810504:PG2T_RS07035
uniprot id: A0A1B1YSX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.