1796620:ADH66 RS12420
gene id: 1796620:ADH66_RS12420
uniprot id: A0A1Z2XSL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1796620:ADH66 RS17900
gene id: 1796620:ADH66_RS17900
uniprot id: A0A1Z2XV88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1796620:ADH66 RS16385
gene id: 1796620:ADH66_RS16385
uniprot id: A0A1Z2XUP2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1796620:ADH66 RS08330
gene id: 1796620:ADH66_RS08330
uniprot id: A0A1Z2XQJ3
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS01935
gene id: 1796620:ADH66_RS01935
uniprot id: A0A1Z2XM64
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1796620:ADH66 RS01490
gene id: 1796620:ADH66_RS01490
uniprot id: A0A1Z2XLW9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1796620:ADH66 RS03915
gene id: 1796620:ADH66_RS03915
uniprot id: A0A1Z2XN49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1796620:ADH66 RS01110
gene id: 1796620:ADH66_RS01110
uniprot id: A0A1Z2XLR5
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS08260
gene id: 1796620:ADH66_RS08260
uniprot id: A0A1Z2XQC4
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1796620:ADH66 RS18210
gene id: 1796620:ADH66_RS18210
uniprot id: A0A1Z2XVD4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1796620:ADH66 RS04065
gene id: 1796620:ADH66_RS04065
uniprot id: A0A1Z2XN96
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1796620:ADH66 RS13860
gene id: 1796620:ADH66_RS13860
uniprot id: A0A1Z2XT65
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1796620:ADH66 RS11730
gene id: 1796620:ADH66_RS11730
uniprot id: A0A1Z2XS31
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS14215
gene id: 1796620:ADH66_RS14215
uniprot id: A0A1Z2XTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS04665
gene id: 1796620:ADH66_RS04665
uniprot id: A0A1Z2XNM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS14015
gene id: 1796620:ADH66_RS14015
uniprot id: A0A1Z2XTA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1796620:ADH66 RS08870
gene id: 1796620:ADH66_RS08870
uniprot id: A0A1Z2XQQ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1796620:ADH66 RS19065
gene id: 1796620:ADH66_RS19065
uniprot id: A0A1Z2XVT1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1796620:ADH66 RS13620
gene id: 1796620:ADH66_RS13620
uniprot id: A0A1Z2XT32
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1796620:ADH66 RS13115
gene id: 1796620:ADH66_RS13115
uniprot id: A0A1Z2XSS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1796620:ADH66 RS01785
gene id: 1796620:ADH66_RS01785
uniprot id: A0A1Z2XM28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1796620:ADH66 RS08585
gene id: 1796620:ADH66_RS08585
uniprot id: A0A1Z2XQM1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1796620:ADH66 RS18625
gene id: 1796620:ADH66_RS18625
uniprot id: A0A1Z2XVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1796620:ADH66 RS10560
gene id: 1796620:ADH66_RS10560
uniprot id: A0A1Z2XRH5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1796620:ADH66 RS01475
gene id: 1796620:ADH66_RS01475
uniprot id: A0A1Z2XLV9
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1796620:ADH66 RS13745
gene id: 1796620:ADH66_RS13745
uniprot id: A0A1Z2XT47
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS02415
gene id: 1796620:ADH66_RS02415
uniprot id: A0A1Z2XMF9
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1796620:ADH66 RS14930
gene id: 1796620:ADH66_RS14930
uniprot id: A0A1Z2XTQ5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1796620:ADH66 RS06150
gene id: 1796620:ADH66_RS06150
uniprot id: A0A1Z2XPA0
names: Similarity
messages: Belongs to the 'phage' integrase family.

1796620:ADH66 RS17565
gene id: 1796620:ADH66_RS17565
uniprot id: A0A1Z2XV38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm

1796620:ADH66 RS16100
gene id: 1796620:ADH66_RS16100
uniprot id: A0A1Z2XUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS03445
gene id: 1796620:ADH66_RS03445
uniprot id: A0A1Z2XMY1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1796620:ADH66 RS02085
gene id: 1796620:ADH66_RS02085
uniprot id: A0A1Z2XM87
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1796620:ADH66 RS07110
gene id: 1796620:ADH66_RS07110
uniprot id: A0A1Z2XPS3
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS14575
gene id: 1796620:ADH66_RS14575
uniprot id: A0A1Z2XTJ6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS00340
gene id: 1796620:ADH66_RS00340
uniprot id: A0A1Z2XLC2
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1796620:ADH66 RS14225
gene id: 1796620:ADH66_RS14225
uniprot id: A0A1Z2XTD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1796620:ADH66 RS05465
gene id: 1796620:ADH66_RS05465
uniprot id: A0A1Z2XNY3
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1796620:ADH66 RS16165
gene id: 1796620:ADH66_RS16165
uniprot id: A0A1Z2XUD0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796620:ADH66 RS09030
gene id: 1796620:ADH66_RS09030
uniprot id: A0A1Z2XQT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1796620:ADH66 RS01900
gene id: 1796620:ADH66_RS01900
uniprot id: A0A1Z2XM67
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1796620:ADH66 RS06560
gene id: 1796620:ADH66_RS06560
uniprot id: A0A1Z2XPI1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1796620:ADH66 RS13510
gene id: 1796620:ADH66_RS13510
uniprot id: A0A1Z2XSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1796620:ADH66 RS08530
gene id: 1796620:ADH66_RS08530
uniprot id: A0A1Z2XQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1796620:ADH66 RS17685
gene id: 1796620:ADH66_RS17685
uniprot id: A0A1Z2XV59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1796620:ADH66 RS11925
gene id: 1796620:ADH66_RS11925
uniprot id: A0A1Z2XWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS00775
gene id: 1796620:ADH66_RS00775
uniprot id: A0A1Z2XLK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS12205
gene id: 1796620:ADH66_RS12205
uniprot id: A0A1Z2XSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS07450
gene id: 1796620:ADH66_RS07450
uniprot id: A0A1Z2XPZ2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1796620:ADH66 RS01850
gene id: 1796620:ADH66_RS01850
uniprot id: A0A1Z2XM45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1796620:ADH66 RS14200
gene id: 1796620:ADH66_RS14200
uniprot id: A0A1Z2XTK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS08630
gene id: 1796620:ADH66_RS08630
uniprot id: A0A1Z2XQN3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796620:ADH66 RS17590
gene id: 1796620:ADH66_RS17590
uniprot id: A0A1Z2XV30
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS18450
gene id: 1796620:ADH66_RS18450
uniprot id: A0A1Z2XVL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1796620:ADH66 RS14075
gene id: 1796620:ADH66_RS14075
uniprot id: A0A1Z2XTA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1796620:ADH66 RS04245
gene id: 1796620:ADH66_RS04245
uniprot id: A0A1Z2XNA5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1796620:ADH66 RS16260
gene id: 1796620:ADH66_RS16260
uniprot id: A0A1Z2XUF5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1796620:ADH66 RS13615
gene id: 1796620:ADH66_RS13615
uniprot id: A0A1Z2XT11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1796620:ADH66 RS18520
gene id: 1796620:ADH66_RS18520
uniprot id: A0A1Z2XVI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1796620:ADH66 RS06530
gene id: 1796620:ADH66_RS06530
uniprot id: A0A1Z2XPK0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1796620:ADH66 RS09290
gene id: 1796620:ADH66_RS09290
uniprot id: A0A1Z2XR11
names: Similarity
messages: Belongs to the asparagine synthetase family.

1796620:ADH66 RS13400
gene id: 1796620:ADH66_RS13400
uniprot id: A0A1Z2XT04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS18145
gene id: 1796620:ADH66_RS18145
uniprot id: A0A1Z2XVB8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS14975
gene id: 1796620:ADH66_RS14975
uniprot id: A0A1Z2XTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1796620:ADH66 RS18730
gene id: 1796620:ADH66_RS18730
uniprot id: A0A1Z2XVQ8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS10645
gene id: 1796620:ADH66_RS10645
uniprot id: A0A1Z2XRJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS10100
gene id: 1796620:ADH66_RS10100
uniprot id: A0A1Z2XRC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1796620:ADH66 RS16600
gene id: 1796620:ADH66_RS16600
uniprot id: A0A1Z2XUT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1796620:ADH66 RS11325
gene id: 1796620:ADH66_RS11325
uniprot id: A0A1Z2XS00
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796620:ADH66 RS18160
gene id: 1796620:ADH66_RS18160
uniprot id: A0A1Z2XVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1796620:ADH66 RS08795
gene id: 1796620:ADH66_RS08795
uniprot id: A0A1Z2XQK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796620:ADH66 RS01925
gene id: 1796620:ADH66_RS01925
uniprot id: A0A1Z2XM68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1796620:ADH66 RS19080
gene id: 1796620:ADH66_RS19080
uniprot id: A0A1Z2XVS0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796620:ADH66 RS07575
gene id: 1796620:ADH66_RS07575
uniprot id: A0A1Z2XQ05
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1796620:ADH66 RS08705
gene id: 1796620:ADH66_RS08705
uniprot id: A0A1Z2XQL4
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

1796620:ADH66 RS04495
gene id: 1796620:ADH66_RS04495
uniprot id: A0A1Z2XNF8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS05175
gene id: 1796620:ADH66_RS05175
uniprot id: A0A1Z2XNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS13275
gene id: 1796620:ADH66_RS13275
uniprot id: A0A1Z2XT08
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS18755
gene id: 1796620:ADH66_RS18755
uniprot id: A0A1Z2XVM4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1796620:ADH66 RS13960
gene id: 1796620:ADH66_RS13960
uniprot id: A0A1Z2XT90
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1796620:ADH66 RS13085
gene id: 1796620:ADH66_RS13085
uniprot id: A0A1Z2XSQ8
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS02935
gene id: 1796620:ADH66_RS02935
uniprot id: A0A1Z2XMN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1796620:ADH66 RS14435
gene id: 1796620:ADH66_RS14435
uniprot id: A0A1Z2XTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1796620:ADH66 RS09955
gene id: 1796620:ADH66_RS09955
uniprot id: A0A1Z2XR99
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS13390
gene id: 1796620:ADH66_RS13390
uniprot id: A0A1Z2XSX8
names: Similarity
messages: Belongs to the FlgD family.

1796620:ADH66 RS17705
gene id: 1796620:ADH66_RS17705
uniprot id: A0A1Z2XWK3
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1796620:ADH66 RS08035
gene id: 1796620:ADH66_RS08035
uniprot id: A0A1Z2XQ85
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS16175
gene id: 1796620:ADH66_RS16175
uniprot id: A0A1Z2XUC3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1796620:ADH66 RS13320
gene id: 1796620:ADH66_RS13320
uniprot id: A0A1Z2XSX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1796620:ADH66 RS06025
gene id: 1796620:ADH66_RS06025
uniprot id: A0A1Z2XP80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS13880
gene id: 1796620:ADH66_RS13880
uniprot id: A0A1Z2XT94
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS02050
gene id: 1796620:ADH66_RS02050
uniprot id: A0A1Z2XM80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1796620:ADH66 RS14155
gene id: 1796620:ADH66_RS14155
uniprot id: A0A1Z2XTD8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1796620:ADH66 RS17790
gene id: 1796620:ADH66_RS17790
uniprot id: A0A1Z2XVC6
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS16090
gene id: 1796620:ADH66_RS16090
uniprot id: A0A1Z2XUF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.

1796620:ADH66 RS06380
gene id: 1796620:ADH66_RS06380
uniprot id: A0A1Z2XPF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1796620:ADH66 RS18485
gene id: 1796620:ADH66_RS18485
uniprot id: A0A1Z2XVI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1796620:ADH66 RS06720
gene id: 1796620:ADH66_RS06720
uniprot id: A0A1Z2XPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1796620:ADH66 RS05770
gene id: 1796620:ADH66_RS05770
uniprot id: A0A1Z2XP41
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS16440
gene id: 1796620:ADH66_RS16440
uniprot id: A0A1Z2XUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS06445
gene id: 1796620:ADH66_RS06445
uniprot id: A0A1Z2XPF7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1796620:ADH66 RS03485
gene id: 1796620:ADH66_RS03485
uniprot id: A0A1Z2XMX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1796620:ADH66 RS04075
gene id: 1796620:ADH66_RS04075
uniprot id: A0A1Z2XN76
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1796620:ADH66 RS06625
gene id: 1796620:ADH66_RS06625
uniprot id: A0A1Z2XPI6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1796620:ADH66 RS13850
gene id: 1796620:ADH66_RS13850
uniprot id: A0A1Z2XTB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1796620:ADH66 RS14870
gene id: 1796620:ADH66_RS14870
uniprot id: A0A1Z2XTN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1796620:ADH66 RS12025
gene id: 1796620:ADH66_RS12025
uniprot id: A0A1Z2XS99
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS00510
gene id: 1796620:ADH66_RS00510
uniprot id: A0A1Z2XLG4
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1796620:ADH66 RS11880
gene id: 1796620:ADH66_RS11880
uniprot id: A0A1Z2XS92
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS11465
gene id: 1796620:ADH66_RS11465
uniprot id: A0A1Z2XS42
names: Similarity
messages: Belongs to the peptidase M29 family.

1796620:ADH66 RS06760
gene id: 1796620:ADH66_RS06760
uniprot id: A0A1Z2XPL6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1796620:ADH66 RS06390
gene id: 1796620:ADH66_RS06390
uniprot id: A0A1Z2XPK2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796620:ADH66 RS18505
gene id: 1796620:ADH66_RS18505
uniprot id: A0A1Z2XVJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1796620:ADH66 RS11310
gene id: 1796620:ADH66_RS11310
uniprot id: A0A1Z2XRW8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1796620:ADH66 RS09380
gene id: 1796620:ADH66_RS09380
uniprot id: A0A1Z2XQW5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1796620:ADH66 RS11030
gene id: 1796620:ADH66_RS11030
uniprot id: A0A1Z2XRS0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS19300
gene id: 1796620:ADH66_RS19300
uniprot id: A0A1Z2XW04
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1796620:ADH66 RS02755
gene id: 1796620:ADH66_RS02755
uniprot id: A0A1Z2XMK2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1796620:ADH66 RS10465
gene id: 1796620:ADH66_RS10465
uniprot id: A0A1Z2XRJ2
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1796620:ADH66 RS14900
gene id: 1796620:ADH66_RS14900
uniprot id: A0A1Z2XTS3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1796620:ADH66 RS04915
gene id: 1796620:ADH66_RS04915
uniprot id: A0A1Z2XNP5
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

1796620:ADH66 RS05440
gene id: 1796620:ADH66_RS05440
uniprot id: A0A1Z2XNY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1796620:ADH66 RS05675
gene id: 1796620:ADH66_RS05675
uniprot id: A0A1Z2XP67
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1796620:ADH66 RS06010
gene id: 1796620:ADH66_RS06010
uniprot id: A0A1Z2XP92
names: Similarity
messages: Belongs to the peptidase S1B family.

1796620:ADH66 RS10280
gene id: 1796620:ADH66_RS10280
uniprot id: A0A1Z2XRD7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1796620:ADH66 RS01740
gene id: 1796620:ADH66_RS01740
uniprot id: A0A1Z2XM30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1796620:ADH66 RS13785
gene id: 1796620:ADH66_RS13785
uniprot id: A0A1Z2XTA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS15740
gene id: 1796620:ADH66_RS15740
uniprot id: A0A1Z2XU40
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS14170
gene id: 1796620:ADH66_RS14170
uniprot id: A0A1Z2XTC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1796620:ADH66 RS02015
gene id: 1796620:ADH66_RS02015
uniprot id: A0A1Z2XM66
names: Similarity
messages: Belongs to the MobA/MobL family.

1796620:ADH66 RS11090
gene id: 1796620:ADH66_RS11090
uniprot id: A0A1Z2XRV0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS17920
gene id: 1796620:ADH66_RS17920
uniprot id: A0A1Z2XVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1796620:ADH66 RS14830
gene id: 1796620:ADH66_RS14830
uniprot id: A0A1Z2XTN3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1796620:ADH66 RS03005
gene id: 1796620:ADH66_RS03005
uniprot id: A0A1Z2XMP7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1796620:ADH66 RS07455
gene id: 1796620:ADH66_RS07455
uniprot id: A0A1Z2XPY7
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796620:ADH66 RS15100
gene id: 1796620:ADH66_RS15100
uniprot id: A0A1Z2XTU3
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1796620:ADH66 RS07700
gene id: 1796620:ADH66_RS07700
uniprot id: A0A1Z2XQ30
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS01205
gene id: 1796620:ADH66_RS01205
uniprot id: A0A1Z2XW55
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1796620:ADH66 RS13970
gene id: 1796620:ADH66_RS13970
uniprot id: A0A1Z2XT88
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796620:ADH66 RS18590
gene id: 1796620:ADH66_RS18590
uniprot id: A0A1Z2XVK2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1796620:ADH66 RS00185
gene id: 1796620:ADH66_RS00185
uniprot id: A0A1Z2XLA5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1796620:ADH66 RS11495
gene id: 1796620:ADH66_RS11495
uniprot id: A0A1Z2XS32
names: Similarity
messages: Belongs to the GARS family.

1796620:ADH66 RS00745
gene id: 1796620:ADH66_RS00745
uniprot id: A0A1Z2XLL1
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1796620:ADH66 RS00260
gene id: 1796620:ADH66_RS00260
uniprot id: A0A1Z2XLA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1796620:ADH66 RS08540
gene id: 1796620:ADH66_RS08540
uniprot id: A0A1Z2XQK7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1796620:ADH66 RS16095
gene id: 1796620:ADH66_RS16095
uniprot id: A0A1Z2XUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS04630
gene id: 1796620:ADH66_RS04630
uniprot id: A0A1Z2XNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1796620:ADH66 RS01660
gene id: 1796620:ADH66_RS01660
uniprot id: A0A1Z2XM08
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1796620:ADH66 RS13795
gene id: 1796620:ADH66_RS13795
uniprot id: A0A1Z2XT60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS13435
gene id: 1796620:ADH66_RS13435
uniprot id: A0A1Z2XSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1796620:ADH66 RS08700
gene id: 1796620:ADH66_RS08700
uniprot id: A0A1Z2XQQ0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1796620:ADH66 RS17930
gene id: 1796620:ADH66_RS17930
uniprot id: A0A1Z2XV93
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS17350
gene id: 1796620:ADH66_RS17350
uniprot id: A0A1Z2XUZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1796620:ADH66 RS05810
gene id: 1796620:ADH66_RS05810
uniprot id: A0A1Z2XP55
names: Caution
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS14025
gene id: 1796620:ADH66_RS14025
uniprot id: A0A1Z2XT96
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1796620:ADH66 RS01760
gene id: 1796620:ADH66_RS01760
uniprot id: A0A1Z2XM36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1796620:ADH66 RS03460
gene id: 1796620:ADH66_RS03460
uniprot id: A0A1Z2XMW3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1796620:ADH66 RS15645
gene id: 1796620:ADH66_RS15645
uniprot id: A0A1Z2XU61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS17605
gene id: 1796620:ADH66_RS17605
uniprot id: A0A1Z2XV99
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS17775
gene id: 1796620:ADH66_RS17775
uniprot id: A0A1Z2XV60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1796620:ADH66 RS13870
gene id: 1796620:ADH66_RS13870
uniprot id: A0A1Z2XWH7
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1796620:ADH66 RS13600
gene id: 1796620:ADH66_RS13600
uniprot id: A0A1Z2XT74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1796620:ADH66 RS07535
gene id: 1796620:ADH66_RS07535
uniprot id: A0A1Z2XQ44
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS11120
gene id: 1796620:ADH66_RS11120
uniprot id: A0A1Z2XS18
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS00515
gene id: 1796620:ADH66_RS00515
uniprot id: A0A1Z2XLF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1796620:ADH66 RS08760
gene id: 1796620:ADH66_RS08760
uniprot id: A0A1Z2XQN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1796620:ADH66 RS17795
gene id: 1796620:ADH66_RS17795
uniprot id: A0A1Z2XV75
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1796620:ADH66 RS13640
gene id: 1796620:ADH66_RS13640
uniprot id: A0A1Z2XT26
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1796620:ADH66 RS01470
gene id: 1796620:ADH66_RS01470
uniprot id: A0A1Z2XLX4
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1796620:ADH66 RS16595
gene id: 1796620:ADH66_RS16595
uniprot id: A0A1Z2XUL1
names: Similarity
messages: Belongs to the RutC family.

1796620:ADH66 RS04865
gene id: 1796620:ADH66_RS04865
uniprot id: A0A1Z2XNN7
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1796620:ADH66 RS07330
gene id: 1796620:ADH66_RS07330
uniprot id: A0A1Z2XQ06
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1796620:ADH66 RS10860
gene id: 1796620:ADH66_RS10860
uniprot id: A0A1Z2XRN7
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS15800
gene id: 1796620:ADH66_RS15800
uniprot id: A0A1Z2XU87
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS18270
gene id: 1796620:ADH66_RS18270
uniprot id: A0A1Z2XWL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796620:ADH66 RS13810
gene id: 1796620:ADH66_RS13810
uniprot id: A0A1Z2XWI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1796620:ADH66 RS08460
gene id: 1796620:ADH66_RS08460
uniprot id: A0A1Z2XQL0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS04540
gene id: 1796620:ADH66_RS04540
uniprot id: A0A1Z2XNG8
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS19505
gene id: 1796620:ADH66_RS19505
uniprot id: A0A1Z2XW00
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS16550
gene id: 1796620:ADH66_RS16550
uniprot id: A0A1Z2XUM5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1796620:ADH66 RS13215
gene id: 1796620:ADH66_RS13215
uniprot id: A0A1Z2XSU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1796620:ADH66 RS02080
gene id: 1796620:ADH66_RS02080
uniprot id: A0A1Z2XM79
names: Similarity
messages: Belongs to the IlvD/Edd family.

1796620:ADH66 RS12100
gene id: 1796620:ADH66_RS12100
uniprot id: A0A1Z2XSD9
names: Similarity
messages: Belongs to the AIR synthase family.

1796620:ADH66 RS14905
gene id: 1796620:ADH66_RS14905
uniprot id: A0A1Z2XTW2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1796620:ADH66 RS08550
gene id: 1796620:ADH66_RS08550
uniprot id: A0A1Z2XQG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1796620:ADH66 RS08490
gene id: 1796620:ADH66_RS08490
uniprot id: A0A1Z2XQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1796620:ADH66 RS18385
gene id: 1796620:ADH66_RS18385
uniprot id: A0A1Z2XVH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1796620:ADH66 RS08300
gene id: 1796620:ADH66_RS08300
uniprot id: A0A1Z2XQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1796620:ADH66 RS04405
gene id: 1796620:ADH66_RS04405
uniprot id: A0A1Z2XNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS05480
gene id: 1796620:ADH66_RS05480
uniprot id: A0A1Z2XNZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1796620:ADH66 RS01480
gene id: 1796620:ADH66_RS01480
uniprot id: A0A1Z2XLX8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1796620:ADH66 RS18180
gene id: 1796620:ADH66_RS18180
uniprot id: A0A1Z2XVE6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1796620:ADH66 RS17670
gene id: 1796620:ADH66_RS17670
uniprot id: A0A1Z2XWK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1796620:ADH66 RS12230
gene id: 1796620:ADH66_RS12230
uniprot id: A0A1Z2XSC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1796620:ADH66 RS06465
gene id: 1796620:ADH66_RS06465
uniprot id: A0A1Z2XPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1796620:ADH66 RS08165
gene id: 1796620:ADH66_RS08165
uniprot id: A0A1Z2XQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS04700
gene id: 1796620:ADH66_RS04700
uniprot id: A0A1Z2XNJ9
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1796620:ADH66 RS01445
gene id: 1796620:ADH66_RS01445
uniprot id: A0A1Z2XLW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1796620:ADH66 RS18515
gene id: 1796620:ADH66_RS18515
uniprot id: A0A1Z2XVK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1796620:ADH66 RS13330
gene id: 1796620:ADH66_RS13330
uniprot id: A0A1Z2XSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1796620:ADH66 RS01505
gene id: 1796620:ADH66_RS01505
uniprot id: A0A1Z2XLY0
names: Similarity
messages: Belongs to the CinA family.

1796620:ADH66 RS17300
gene id: 1796620:ADH66_RS17300
uniprot id: A0A1Z2XUY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1796620:ADH66 RS16450
gene id: 1796620:ADH66_RS16450
uniprot id: A0A1Z2XUJ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1796620:ADH66 RS15520
gene id: 1796620:ADH66_RS15520
uniprot id: A0A1Z2XWJ5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1796620:ADH66 RS09355
gene id: 1796620:ADH66_RS09355
uniprot id: A0A1Z2XQZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1796620:ADH66 RS10165
gene id: 1796620:ADH66_RS10165
uniprot id: A0A1Z2XRD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1796620:ADH66 RS08255
gene id: 1796620:ADH66_RS08255
uniprot id: A0A1Z2XQG4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1796620:ADH66 RS08080
gene id: 1796620:ADH66_RS08080
uniprot id: A0A1Z2XQA5
names: Similarity
messages: Belongs to the DapA family.

1796620:ADH66 RS09060
gene id: 1796620:ADH66_RS09060
uniprot id: A0A1Z2XWB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1796620:ADH66 RS09260
gene id: 1796620:ADH66_RS09260
uniprot id: A0A1Z2XQV1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1796620:ADH66 RS06605
gene id: 1796620:ADH66_RS06605
uniprot id: A0A1Z2XPN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1796620:ADH66 RS13120
gene id: 1796620:ADH66_RS13120
uniprot id: A0A1Z2XSY1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796620:ADH66 RS13645
gene id: 1796620:ADH66_RS13645
uniprot id: A0A1Z2XT30
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS15650
gene id: 1796620:ADH66_RS15650
uniprot id: A0A1Z2XU81
names: Caution
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS14220
gene id: 1796620:ADH66_RS14220
uniprot id: A0A1Z2XTH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS06210
gene id: 1796620:ADH66_RS06210
uniprot id: A0A1Z2XPB1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS19535
gene id: 1796620:ADH66_RS19535
uniprot id: A0A1Z2XW34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS04375
gene id: 1796620:ADH66_RS04375
uniprot id: A0A1Z2XND8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS09335
gene id: 1796620:ADH66_RS09335
uniprot id: A0A1Z2XQY9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1796620:ADH66 RS04590
gene id: 1796620:ADH66_RS04590
uniprot id: A0A1Z2XNH9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1796620:ADH66 RS13205
gene id: 1796620:ADH66_RS13205
uniprot id: A0A1Z2XSY6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS04530
gene id: 1796620:ADH66_RS04530
uniprot id: A0A1Z2XNG4
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS06410
gene id: 1796620:ADH66_RS06410
uniprot id: A0A1Z2XPF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1796620:ADH66 RS10000
gene id: 1796620:ADH66_RS10000
uniprot id: A0A1Z2XR78
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS18510
gene id: 1796620:ADH66_RS18510
uniprot id: A0A1Z2XVK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1796620:ADH66 RS01610
gene id: 1796620:ADH66_RS01610
uniprot id: A0A1Z2XLZ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS09310
gene id: 1796620:ADH66_RS09310
uniprot id: A0A1Z2XQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS00250
gene id: 1796620:ADH66_RS00250
uniprot id: A0A1Z2XLB0
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS02545
gene id: 1796620:ADH66_RS02545
uniprot id: A0A1Z2XMH9
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS10635
gene id: 1796620:ADH66_RS10635
uniprot id: A0A1Z2XWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS00830
gene id: 1796620:ADH66_RS00830
uniprot id: A0A1Z2XLL6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1796620:ADH66 RS07580
gene id: 1796620:ADH66_RS07580
uniprot id: A0A1Z2XQ02
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS04045
gene id: 1796620:ADH66_RS04045
uniprot id: A0A1Z2XN71
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS02390
gene id: 1796620:ADH66_RS02390
uniprot id: A0A1Z2XMF6
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1796620:ADH66 RS18135
gene id: 1796620:ADH66_RS18135
uniprot id: A0A1Z2XVC3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1796620:ADH66 RS04985
gene id: 1796620:ADH66_RS04985
uniprot id: A0A1Z2XNR6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1796620:ADH66 RS02240
gene id: 1796620:ADH66_RS02240
uniprot id: A0A1Z2XMC0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1796620:ADH66 RS04270
gene id: 1796620:ADH66_RS04270
uniprot id: A0A1Z2XNC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1796620:ADH66 RS13980
gene id: 1796620:ADH66_RS13980
uniprot id: A0A1Z2XTB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1796620:ADH66 RS18600
gene id: 1796620:ADH66_RS18600
uniprot id: A0A1Z2XVQ7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1796620:ADH66 RS16205
gene id: 1796620:ADH66_RS16205
uniprot id: A0A1Z2XUE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS02525
gene id: 1796620:ADH66_RS02525
uniprot id: A0A1Z2XMK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1796620:ADH66 RS02735
gene id: 1796620:ADH66_RS02735
uniprot id: A0A1Z2XML0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1796620:ADH66 RS01440
gene id: 1796620:ADH66_RS01440
uniprot id: A0A1Z2XLW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1796620:ADH66 RS00410
gene id: 1796620:ADH66_RS00410
uniprot id: A0A1Z2XLD6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1796620:ADH66 RS02520
gene id: 1796620:ADH66_RS02520
uniprot id: A0A1Z2XMG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796620:ADH66 RS11920
gene id: 1796620:ADH66_RS11920
uniprot id: A0A1Z2XS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS08465
gene id: 1796620:ADH66_RS08465
uniprot id: A0A1Z2XQH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1796620:ADH66 RS09075
gene id: 1796620:ADH66_RS09075
uniprot id: A0A1Z2XQW4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1796620:ADH66 RS02710
gene id: 1796620:ADH66_RS02710
uniprot id: A0A1Z2XMJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1796620:ADH66 RS00810
gene id: 1796620:ADH66_RS00810
uniprot id: A0A1Z2XLM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1796620:ADH66 RS05025
gene id: 1796620:ADH66_RS05025
uniprot id: A0A1Z2XNQ4
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS04840
gene id: 1796620:ADH66_RS04840
uniprot id: A0A1Z2XNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS18580
gene id: 1796620:ADH66_RS18580
uniprot id: A0A1Z2XVJ5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS17635
gene id: 1796620:ADH66_RS17635
uniprot id: A0A1Z2XV49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1796620:ADH66 RS10285
gene id: 1796620:ADH66_RS10285
uniprot id: A0A1Z2XRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1796620:ADH66 RS14265
gene id: 1796620:ADH66_RS14265
uniprot id: A0A1Z2XTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1796620:ADH66 RS11575
gene id: 1796620:ADH66_RS11575
uniprot id: A0A1Z2XS36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1796620:ADH66 RS18465
gene id: 1796620:ADH66_RS18465
uniprot id: A0A1Z2XVJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1796620:ADH66 RS11650
gene id: 1796620:ADH66_RS11650
uniprot id: A0A1Z2XS23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1796620:ADH66 RS04585
gene id: 1796620:ADH66_RS04585
uniprot id: A0A1Z2XNJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1796620:ADH66 RS08445
gene id: 1796620:ADH66_RS08445
uniprot id: A0A1Z2XQK6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1796620:ADH66 RS02825
gene id: 1796620:ADH66_RS02825
uniprot id: A0A1Z2XML1
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1796620:ADH66 RS09025
gene id: 1796620:ADH66_RS09025
uniprot id: A0A1Z2XQQ9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1796620:ADH66 RS05050
gene id: 1796620:ADH66_RS05050
uniprot id: A0A1Z2XNR1
names: Similarity
messages: Belongs to the RNase H family.

1796620:ADH66 RS04605
gene id: 1796620:ADH66_RS04605
uniprot id: A0A1Z2XNH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1796620:ADH66 RS13815
gene id: 1796620:ADH66_RS13815
uniprot id: A0A1Z2XTB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1796620:ADH66 RS17940
gene id: 1796620:ADH66_RS17940
uniprot id: A0A1Z2XV87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1796620:ADH66 RS10305
gene id: 1796620:ADH66_RS10305
uniprot id: A0A1Z2XRF9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS14085
gene id: 1796620:ADH66_RS14085
uniprot id: A0A1Z2XTG4
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1796620:ADH66 RS13990
gene id: 1796620:ADH66_RS13990
uniprot id: A0A1Z2XTE7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1796620:ADH66 RS17655
gene id: 1796620:ADH66_RS17655
uniprot id: A0A1Z2XV43
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1796620:ADH66 RS14100
gene id: 1796620:ADH66_RS14100
uniprot id: A0A1Z2XTA9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1796620:ADH66 RS07255
gene id: 1796620:ADH66_RS07255
uniprot id: A0A1Z2XPU6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS08225
gene id: 1796620:ADH66_RS08225
uniprot id: A0A1Z2XQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1796620:ADH66 RS01095
gene id: 1796620:ADH66_RS01095
uniprot id: A0A1Z2XLQ7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS00125
gene id: 1796620:ADH66_RS00125
uniprot id: A0A1Z2XL81
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

1796620:ADH66 RS14475
gene id: 1796620:ADH66_RS14475
uniprot id: A0A1Z2XTH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1796620:ADH66 RS00680
gene id: 1796620:ADH66_RS00680
uniprot id: A0A1Z2XLI0
names: Similarity
messages: Belongs to the UPF0237 family.

1796620:ADH66 RS09585
gene id: 1796620:ADH66_RS09585
uniprot id: A0A1Z2XR35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS17610
gene id: 1796620:ADH66_RS17610
uniprot id: A0A1Z2XV46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1796620:ADH66 RS02340
gene id: 1796620:ADH66_RS02340
uniprot id: A0A1Z2XMC8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1796620:ADH66 RS19340
gene id: 1796620:ADH66_RS19340
uniprot id: A0A1Z2XW08
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796620:ADH66 RS04805
gene id: 1796620:ADH66_RS04805
uniprot id: A0A1Z2XNN2
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS16445
gene id: 1796620:ADH66_RS16445
uniprot id: A0A1Z2XUM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS09330
gene id: 1796620:ADH66_RS09330
uniprot id: A0A1Z2XQY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1796620:ADH66 RS07670
gene id: 1796620:ADH66_RS07670
uniprot id: A0A1Z2XQ28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796620:ADH66 RS09670
gene id: 1796620:ADH66_RS09670
uniprot id: A0A1Z2XR25
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS02225
gene id: 1796620:ADH66_RS02225
uniprot id: A0A1Z2XMA7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1796620:ADH66 RS10340
gene id: 1796620:ADH66_RS10340
uniprot id: A0A1Z2XRG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1796620:ADH66 RS15570
gene id: 1796620:ADH66_RS15570
uniprot id: A0A1Z2XU80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1796620:ADH66 RS14790
gene id: 1796620:ADH66_RS14790
uniprot id: A0A1Z2XTW1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS16180
gene id: 1796620:ADH66_RS16180
uniprot id: A0A1Z2XUJ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1796620:ADH66 RS08620
gene id: 1796620:ADH66_RS08620
uniprot id: A0A1Z2XQI1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1796620:ADH66 RS08290
gene id: 1796620:ADH66_RS08290
uniprot id: A0A1Z2XQD4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS09070
gene id: 1796620:ADH66_RS09070
uniprot id: A0A1Z2XQT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS00105
gene id: 1796620:ADH66_RS00105
uniprot id: A0A1Z2XL73
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1796620:ADH66 RS02455
gene id: 1796620:ADH66_RS02455
uniprot id: A0A1Z2XMF8
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the flavodoxin reductase family.
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
messages: Mediates electron transfer from NADH to oxygen, reducing it to water. This modular protein has 3 redox cofactors, in other organisms the same activity requires 2 or 3 proteins.

1796620:ADH66 RS02335
gene id: 1796620:ADH66_RS02335
uniprot id: A0A1Z2XME7
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1796620:ADH66 RS15680
gene id: 1796620:ADH66_RS15680
uniprot id: A0A1Z2XU30
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1796620:ADH66 RS03170
gene id: 1796620:ADH66_RS03170
uniprot id: A0A1Z2XMW6
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1796620:ADH66 RS14970
gene id: 1796620:ADH66_RS14970
uniprot id: A0A1Z2XTS6
names: Similarity
messages: Belongs to the peptidase M18 family.

1796620:ADH66 RS12200
gene id: 1796620:ADH66_RS12200
uniprot id: A0A1Z2XSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS13200
gene id: 1796620:ADH66_RS13200
uniprot id: A0A1Z2XST9
names: Similarity
messages: Belongs to the peptidase U62 family.

1796620:ADH66 RS17520
gene id: 1796620:ADH66_RS17520
uniprot id: A0A1Z2XV24
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1796620:ADH66 RS05705
gene id: 1796620:ADH66_RS05705
uniprot id: A0A1Z2XP32
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS18390
gene id: 1796620:ADH66_RS18390
uniprot id: A0A1Z2XVK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1796620:ADH66 RS01200
gene id: 1796620:ADH66_RS01200
uniprot id: A0A1Z2XLT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796620:ADH66 RS09300
gene id: 1796620:ADH66_RS09300
uniprot id: A0A1Z2XQV9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1796620:ADH66 RS18130
gene id: 1796620:ADH66_RS18130
uniprot id: A0A1Z2XVC0
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS18365
gene id: 1796620:ADH66_RS18365
uniprot id: A0A1Z2XVF8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1796620:ADH66 RS11050
gene id: 1796620:ADH66_RS11050
uniprot id: A0A1Z2XRR6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS12215
gene id: 1796620:ADH66_RS12215
uniprot id: A0A1Z2XSB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1796620:ADH66 RS01875
gene id: 1796620:ADH66_RS01875
uniprot id: A0A1Z2XM54
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1796620:ADH66 RS08115
gene id: 1796620:ADH66_RS08115
uniprot id: A0A1Z2XQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS13825
gene id: 1796620:ADH66_RS13825
uniprot id: A0A1Z2XWG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1796620:ADH66 RS00660
gene id: 1796620:ADH66_RS00660
uniprot id: A0A1Z2XLI8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1796620:ADH66 RS06165
gene id: 1796620:ADH66_RS06165
uniprot id: A0A1Z2XPB5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1796620:ADH66 RS13725
gene id: 1796620:ADH66_RS13725
uniprot id: A0A1Z2XT50
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1796620:ADH66 RS11590
gene id: 1796620:ADH66_RS11590
uniprot id: A0A1Z2XS09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1796620:ADH66 RS04215
gene id: 1796620:ADH66_RS04215
uniprot id: A0A1Z2XNB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS11380
gene id: 1796620:ADH66_RS11380
uniprot id: A0A1Z2XRX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1796620:ADH66 RS16160
gene id: 1796620:ADH66_RS16160
uniprot id: A0A1Z2XUE3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1796620:ADH66 RS10405
gene id: 1796620:ADH66_RS10405
uniprot id: A0A1Z2XRJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796620:ADH66 RS02370
gene id: 1796620:ADH66_RS02370
uniprot id: A0A1Z2XMD8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1796620:ADH66 RS14405
gene id: 1796620:ADH66_RS14405
uniprot id: A0A1Z2XTJ4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1796620:ADH66 RS15675
gene id: 1796620:ADH66_RS15675
uniprot id: A0A1Z2XU42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS01780
gene id: 1796620:ADH66_RS01780
uniprot id: A0A1Z2XM27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1796620:ADH66 RS03165
gene id: 1796620:ADH66_RS03165
uniprot id: A0A1Z2XMT1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796620:ADH66 RS03785
gene id: 1796620:ADH66_RS03785
uniprot id: A0A1Z2XN23
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS07440
gene id: 1796620:ADH66_RS07440
uniprot id: A0A1Z2XPZ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1796620:ADH66 RS14460
gene id: 1796620:ADH66_RS14460
uniprot id: A0A1Z2XTG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS06195
gene id: 1796620:ADH66_RS06195
uniprot id: A0A1Z2XPE4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1796620:ADH66 RS17600
gene id: 1796620:ADH66_RS17600
uniprot id: A0A1Z2XV36
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS10295
gene id: 1796620:ADH66_RS10295
uniprot id: A0A1Z2XRC8
names: Similarity
messages: Belongs to the TlyA family.

1796620:ADH66 RS14885
gene id: 1796620:ADH66_RS14885
uniprot id: A0A1Z2XTP4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1796620:ADH66 RS14235
gene id: 1796620:ADH66_RS14235
uniprot id: A0A1Z2XTD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1796620:ADH66 RS13800
gene id: 1796620:ADH66_RS13800
uniprot id: A0A1Z2XT56
names: Similarity
messages: Belongs to the transpeptidase family.

1796620:ADH66 RS01945
gene id: 1796620:ADH66_RS01945
uniprot id: A0A1Z2XM55
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1796620:ADH66 RS00010
gene id: 1796620:ADH66_RS00010
uniprot id: A0A1Z2XL55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1796620:ADH66 RS19320
gene id: 1796620:ADH66_RS19320
uniprot id: A0A1Z2XVX3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796620:ADH66 RS13105
gene id: 1796620:ADH66_RS13105
uniprot id: A0A1Z2XSS4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1796620:ADH66 RS17375
gene id: 1796620:ADH66_RS17375
uniprot id: A0A1Z2XV07
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1796620:ADH66 RS13470
gene id: 1796620:ADH66_RS13470
uniprot id: A0A1Z2XT02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1796620:ADH66 RS13490
gene id: 1796620:ADH66_RS13490
uniprot id: A0A1Z2XSZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1796620:ADH66 RS14440
gene id: 1796620:ADH66_RS14440
uniprot id: A0A1Z2XTJ2
names: Similarity
messages: Belongs to the transpeptidase family.

1796620:ADH66 RS16395
gene id: 1796620:ADH66_RS16395
uniprot id: A0A1Z2XUL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1796620:ADH66 RS01690
gene id: 1796620:ADH66_RS01690
uniprot id: A0A1Z2XM15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1796620:ADH66 RS08945
gene id: 1796620:ADH66_RS08945
uniprot id: A0A1Z2XQQ2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1796620:ADH66 RS17965
gene id: 1796620:ADH66_RS17965
uniprot id: A0A1Z2XVQ0
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS11625
gene id: 1796620:ADH66_RS11625
uniprot id: A0A1Z2XS45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1796620:ADH66 RS07325
gene id: 1796620:ADH66_RS07325
uniprot id: A0A1Z2XPW0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1796620:ADH66 RS02965
gene id: 1796620:ADH66_RS02965
uniprot id: A0A1Z2XMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS17735
gene id: 1796620:ADH66_RS17735
uniprot id: A0A1Z2XV67
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1796620:ADH66 RS12415
gene id: 1796620:ADH66_RS12415
uniprot id: A0A1Z2XSF2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS17265
gene id: 1796620:ADH66_RS17265
uniprot id: A0A1Z2XV10
names: Similarity
messages: Belongs to the DtxR/MntR family.

1796620:ADH66 RS14820
gene id: 1796620:ADH66_RS14820
uniprot id: A0A1Z2XTP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1796620:ADH66 RS11250
gene id: 1796620:ADH66_RS11250
uniprot id: A0A1Z2XRV6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS09870
gene id: 1796620:ADH66_RS09870
uniprot id: A0A1Z2XR75
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS09565
gene id: 1796620:ADH66_RS09565
uniprot id: A0A1Z2XR06
names: Similarity
messages: Belongs to the thioredoxin family.

1796620:ADH66 RS13585
gene id: 1796620:ADH66_RS13585
uniprot id: A0A1Z2XT20
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS01635
gene id: 1796620:ADH66_RS01635
uniprot id: A0A1Z2XM12
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1796620:ADH66 RS04835
gene id: 1796620:ADH66_RS04835
uniprot id: A0A1Z2XNR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS15265
gene id: 1796620:ADH66_RS15265
uniprot id: A0A1Z2XTY0
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS07870
gene id: 1796620:ADH66_RS07870
uniprot id: A0A1Z2XW84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS00210
gene id: 1796620:ADH66_RS00210
uniprot id: A0A1Z2XLC1
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

1796620:ADH66 RS03905
gene id: 1796620:ADH66_RS03905
uniprot id: A0A1Z2XN50
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS01650
gene id: 1796620:ADH66_RS01650
uniprot id: A0A1Z2XM04
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1796620:ADH66 RS18565
gene id: 1796620:ADH66_RS18565
uniprot id: A0A1Z2XVL1
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1796620:ADH66 RS06030
gene id: 1796620:ADH66_RS06030
uniprot id: A0A1Z2XP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS01545
gene id: 1796620:ADH66_RS01545
uniprot id: A0A1Z2XLY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1796620:ADH66 RS08560
gene id: 1796620:ADH66_RS08560
uniprot id: A0A1Z2XQK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1796620:ADH66 RS06135
gene id: 1796620:ADH66_RS06135
uniprot id: A0A1Z2XP97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS16410
gene id: 1796620:ADH66_RS16410
uniprot id: A0A1Z2XUI1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1796620:ADH66 RS06385
gene id: 1796620:ADH66_RS06385
uniprot id: A0A1Z2XPF9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1796620:ADH66 RS13255
gene id: 1796620:ADH66_RS13255
uniprot id: A0A1Z2XT03
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796620:ADH66 RS14935
gene id: 1796620:ADH66_RS14935
uniprot id: A0A1Z2XTP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1796620:ADH66 RS05995
gene id: 1796620:ADH66_RS05995
uniprot id: A0A1Z2XP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS02575
gene id: 1796620:ADH66_RS02575
uniprot id: A0A1Z2XML6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1796620:ADH66 RS05115
gene id: 1796620:ADH66_RS05115
uniprot id: A0A1Z2XNS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS12265
gene id: 1796620:ADH66_RS12265
uniprot id: A0A1Z2XSD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1796620:ADH66 RS02780
gene id: 1796620:ADH66_RS02780
uniprot id: A0A1Z2XMM3
names: Function
names: Subunit
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1796620:ADH66 RS18380
gene id: 1796620:ADH66_RS18380
uniprot id: A0A1Z2XVM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1796620:ADH66 RS07380
gene id: 1796620:ADH66_RS07380
uniprot id: A0A1Z2XQ22
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1796620:ADH66 RS17360
gene id: 1796620:ADH66_RS17360
uniprot id: A0A1Z2XV63
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1796620:ADH66 RS17305
gene id: 1796620:ADH66_RS17305
uniprot id: A0A1Z2XUX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796620:ADH66 RS18245
gene id: 1796620:ADH66_RS18245
uniprot id: A0A1Z2XVE1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1796620:ADH66 RS05870
gene id: 1796620:ADH66_RS05870
uniprot id: A0A1Z2XP61
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1796620:ADH66 RS00280
gene id: 1796620:ADH66_RS00280
uniprot id: A0A1Z2XLB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1796620:ADH66 RS14430
gene id: 1796620:ADH66_RS14430
uniprot id: A0A1Z2XTG3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1796620:ADH66 RS05830
gene id: 1796620:ADH66_RS05830
uniprot id: A0A1Z2XP59
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1796620:ADH66 RS19455
gene id: 1796620:ADH66_RS19455
uniprot id: A0A1Z2XVZ5
names: Similarity
messages: Belongs to the SleB family.

1796620:ADH66 RS15780
gene id: 1796620:ADH66_RS15780
uniprot id: A0A1Z2XU57
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1796620:ADH66 RS18405
gene id: 1796620:ADH66_RS18405
uniprot id: A0A1Z2XVI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1796620:ADH66 RS13140
gene id: 1796620:ADH66_RS13140
uniprot id: A0A1Z2XSU2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796620:ADH66 RS00245
gene id: 1796620:ADH66_RS00245
uniprot id: A0A1Z2XW44
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1796620:ADH66 RS03050
gene id: 1796620:ADH66_RS03050
uniprot id: A0A1Z2XMU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1796620:ADH66 RS18440
gene id: 1796620:ADH66_RS18440
uniprot id: A0A1Z2XVM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1796620:ADH66 RS13595
gene id: 1796620:ADH66_RS13595
uniprot id: A0A1Z2XT18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1796620:ADH66 RS05500
gene id: 1796620:ADH66_RS05500
uniprot id: A0A1Z2XP07
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1796620:ADH66 RS02705
gene id: 1796620:ADH66_RS02705
uniprot id: A0A1Z2XMK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS10200
gene id: 1796620:ADH66_RS10200
uniprot id: A0A1Z2XRB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS07960
gene id: 1796620:ADH66_RS07960
uniprot id: A0A1Z2XQ84
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1796620:ADH66 RS18630
gene id: 1796620:ADH66_RS18630
uniprot id: A0A1Z2XVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1796620:ADH66 RS14880
gene id: 1796620:ADH66_RS14880
uniprot id: A0A1Z2XTN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1796620:ADH66 RS18050
gene id: 1796620:ADH66_RS18050
uniprot id: A0A1Z2XVB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1796620:ADH66 RS09370
gene id: 1796620:ADH66_RS09370
uniprot id: A0A1Z2XW95
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1796620:ADH66 RS00460
gene id: 1796620:ADH66_RS00460
uniprot id: A0A1Z2XLF7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1796620:ADH66 RS13425
gene id: 1796620:ADH66_RS13425
uniprot id: A0A1Z2XT34
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1796620:ADH66 RS14485
gene id: 1796620:ADH66_RS14485
uniprot id: A0A1Z2XTQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1796620:ADH66 RS13855
gene id: 1796620:ADH66_RS13855
uniprot id: A0A1Z2XT71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1796620:ADH66 RS01250
gene id: 1796620:ADH66_RS01250
uniprot id: A0A1Z2XLT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1796620:ADH66 RS10470
gene id: 1796620:ADH66_RS10470
uniprot id: A0A1Z2XRJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796620:ADH66 RS13475
gene id: 1796620:ADH66_RS13475
uniprot id: A0A1Z2XT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1796620:ADH66 RS07790
gene id: 1796620:ADH66_RS07790
uniprot id: A0A1Z2XQ48
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS01675
gene id: 1796620:ADH66_RS01675
uniprot id: A0A1Z2XM11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1796620:ADH66 RS07040
gene id: 1796620:ADH66_RS07040
uniprot id: A0A1Z2XPS4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1796620:ADH66 RS16910
gene id: 1796620:ADH66_RS16910
uniprot id: A0A1Z2XUS3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS04515
gene id: 1796620:ADH66_RS04515
uniprot id: A0A1Z2XNG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS07445
gene id: 1796620:ADH66_RS07445
uniprot id: A0A1Z2XQ32
names: Similarity
messages: Belongs to the FemABX family.

1796620:ADH66 RS13370
gene id: 1796620:ADH66_RS13370
uniprot id: A0A1Z2XT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1796620:ADH66 RS01495
gene id: 1796620:ADH66_RS01495
uniprot id: A0A1Z2XLX5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1796620:ADH66 RS07805
gene id: 1796620:ADH66_RS07805
uniprot id: A0A1Z2XQ42
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS04345
gene id: 1796620:ADH66_RS04345
uniprot id: A0A1Z2XNC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1796620:ADH66 RS13935
gene id: 1796620:ADH66_RS13935
uniprot id: A0A1Z2XTD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS16265
gene id: 1796620:ADH66_RS16265
uniprot id: A0A1Z2XUE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1796620:ADH66 RS17760
gene id: 1796620:ADH66_RS17760
uniprot id: A0A1Z2XV64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1796620:ADH66 RS00190
gene id: 1796620:ADH66_RS00190
uniprot id: A0A1Z2XW29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1796620:ADH66 RS11520
gene id: 1796620:ADH66_RS11520
uniprot id: A0A1Z2XS29
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1796620:ADH66 RS18330
gene id: 1796620:ADH66_RS18330
uniprot id: A0A1Z2XWK2
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS06630
gene id: 1796620:ADH66_RS06630
uniprot id: A0A1Z2XPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1796620:ADH66 RS08935
gene id: 1796620:ADH66_RS08935
uniprot id: A0A1Z2XQU2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1796620:ADH66 RS19395
gene id: 1796620:ADH66_RS19395
uniprot id: A0A1Z2XW17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1796620:ADH66 RS18220
gene id: 1796620:ADH66_RS18220
uniprot id: A0A1Z2XVF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1796620:ADH66 RS01965
gene id: 1796620:ADH66_RS01965
uniprot id: A0A1Z2XM72
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1796620:ADH66 RS05790
gene id: 1796620:ADH66_RS05790
uniprot id: A0A1Z2XP84
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1796620:ADH66 RS16370
gene id: 1796620:ADH66_RS16370
uniprot id: A0A1Z2XUG7
names: Subcellular Location Annotation
messages: Cell membrane

1796620:ADH66 RS04400
gene id: 1796620:ADH66_RS04400
uniprot id: A0A1Z2XNJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1796620:ADH66 RS00355
gene id: 1796620:ADH66_RS00355
uniprot id: A0A1Z2XLD0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS17895
gene id: 1796620:ADH66_RS17895
uniprot id: A0A1Z2XVE5
names: Similarity
messages: Belongs to the UPF0297 family.

1796620:ADH66 RS06615
gene id: 1796620:ADH66_RS06615
uniprot id: A0A1Z2XPK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1796620:ADH66 RS12665
gene id: 1796620:ADH66_RS12665
uniprot id: A0A1Z2XSQ0
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS10150
gene id: 1796620:ADH66_RS10150
uniprot id: A0A1Z2XRA7
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS11605
gene id: 1796620:ADH66_RS11605
uniprot id: A0A1Z2XS17
names: Similarity
messages: Belongs to the peptidase S66 family.

1796620:ADH66 RS01705
gene id: 1796620:ADH66_RS01705
uniprot id: A0A1Z2XM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

1796620:ADH66 RS01695
gene id: 1796620:ADH66_RS01695
uniprot id: A0A1Z2XM13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1796620:ADH66 RS13775
gene id: 1796620:ADH66_RS13775
uniprot id: A0A1Z2XT62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS08865
gene id: 1796620:ADH66_RS08865
uniprot id: A0A1Z2XQR7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1796620:ADH66 RS18370
gene id: 1796620:ADH66_RS18370
uniprot id: A0A1Z2XVG3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1796620:ADH66 RS08685
gene id: 1796620:ADH66_RS08685
uniprot id: A0A1Z2XQJ0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS11535
gene id: 1796620:ADH66_RS11535
uniprot id: A0A1Z2XS02
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1796620:ADH66 RS01715
gene id: 1796620:ADH66_RS01715
uniprot id: A0A1Z2XM19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1796620:ADH66 RS18475
gene id: 1796620:ADH66_RS18475
uniprot id: A0A1Z2XVI5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1796620:ADH66 RS11630
gene id: 1796620:ADH66_RS11630
uniprot id: A0A1Z2XWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1796620:ADH66 RS09375
gene id: 1796620:ADH66_RS09375
uniprot id: A0A1Z2XQW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1796620:ADH66 RS16200
gene id: 1796620:ADH66_RS16200
uniprot id: A0A1Z2XUE7
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS05000
gene id: 1796620:ADH66_RS05000
uniprot id: A0A1Z2XNR5
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS04620
gene id: 1796620:ADH66_RS04620
uniprot id: A0A1Z2XNI5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1796620:ADH66 RS04320
gene id: 1796620:ADH66_RS04320
uniprot id: A0A1Z2XND1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1796620:ADH66 RS03750
gene id: 1796620:ADH66_RS03750
uniprot id: A0A1Z2XN21
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796620:ADH66 RS01980
gene id: 1796620:ADH66_RS01980
uniprot id: A0A1Z2XM70
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1796620:ADH66 RS09015
gene id: 1796620:ADH66_RS09015
uniprot id: A0A1Z2XQR4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1796620:ADH66 RS10910
gene id: 1796620:ADH66_RS10910
uniprot id: A0A1Z2XRN0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS13195
gene id: 1796620:ADH66_RS13195
uniprot id: A0A1Z2XSU8
names: Similarity
messages: Belongs to the peptidase U62 family.

1796620:ADH66 RS13845
gene id: 1796620:ADH66_RS13845
uniprot id: A0A1Z2XT67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1796620:ADH66 RS00435
gene id: 1796620:ADH66_RS00435
uniprot id: A0A1Z2XLE3
names: Similarity
messages: Belongs to the thioredoxin family.

1796620:ADH66 RS00735
gene id: 1796620:ADH66_RS00735
uniprot id: A0A1Z2XLJ0
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1796620:ADH66 RS05210
gene id: 1796620:ADH66_RS05210
uniprot id: A0A1Z2XNV2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS13365
gene id: 1796620:ADH66_RS13365
uniprot id: A0A1Z2XSX2
names: Similarity
messages: Belongs to the MotB family.

1796620:ADH66 RS18435
gene id: 1796620:ADH66_RS18435
uniprot id: A0A1Z2XVG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1796620:ADH66 RS13350
gene id: 1796620:ADH66_RS13350
uniprot id: A0A1Z2XT33
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS08420
gene id: 1796620:ADH66_RS08420
uniprot id: A0A1Z2XQJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS13865
gene id: 1796620:ADH66_RS13865
uniprot id: A0A1Z2XT68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1796620:ADH66 RS14270
gene id: 1796620:ADH66_RS14270
uniprot id: A0A1Z2XTI1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1796620:ADH66 RS09010
gene id: 1796620:ADH66_RS09010
uniprot id: A0A1Z2XQV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1796620:ADH66 RS04435
gene id: 1796620:ADH66_RS04435
uniprot id: A0A1Z2XNE3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1796620:ADH66 RS13840
gene id: 1796620:ADH66_RS13840
uniprot id: A0A1Z2XT76
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1796620:ADH66 RS00240
gene id: 1796620:ADH66_RS00240
uniprot id: A0A1Z2XLB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS19465
gene id: 1796620:ADH66_RS19465
uniprot id: A0A1Z2XW43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS06585
gene id: 1796620:ADH66_RS06585
uniprot id: A0A1Z2XPJ4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1796620:ADH66 RS13325
gene id: 1796620:ADH66_RS13325
uniprot id: A0A1Z2XSW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1796620:ADH66 RS12245
gene id: 1796620:ADH66_RS12245
uniprot id: A0A1Z2XSE1
names: Subcellular Location Annotation
messages: Cell membrane

1796620:ADH66 RS08855
gene id: 1796620:ADH66_RS08855
uniprot id: A0A1Z2XQL7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1796620:ADH66 RS13225
gene id: 1796620:ADH66_RS13225
uniprot id: A0A1Z2XSZ8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS04645
gene id: 1796620:ADH66_RS04645
uniprot id: A0A1Z2XNK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS18645
gene id: 1796620:ADH66_RS18645
uniprot id: A0A1Z2XVK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1796620:ADH66 RS18610
gene id: 1796620:ADH66_RS18610
uniprot id: A0A1Z2XVP7
names: Similarity
messages: Belongs to the ribF family.

1796620:ADH66 RS08605
gene id: 1796620:ADH66_RS08605
uniprot id: A0A1Z2XQL8
names: Similarity
messages: Belongs to the aldose epimerase family.

1796620:ADH66 RS08520
gene id: 1796620:ADH66_RS08520
uniprot id: A0A1Z2XQI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS03325
gene id: 1796620:ADH66_RS03325
uniprot id: A0A1Z2XMU2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796620:ADH66 RS02640
gene id: 1796620:ADH66_RS02640
uniprot id: A0A1Z2XMI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1796620:ADH66 RS19530
gene id: 1796620:ADH66_RS19530
uniprot id: A0A1Z2XW15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1796620:ADH66 RS12280
gene id: 1796620:ADH66_RS12280
uniprot id: A0A1Z2XSD8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS10170
gene id: 1796620:ADH66_RS10170
uniprot id: A0A1Z2XRA9
names: Similarity
messages: Belongs to the ThiD family.

1796620:ADH66 RS16580
gene id: 1796620:ADH66_RS16580
uniprot id: A0A1Z2XUL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS12275
gene id: 1796620:ADH66_RS12275
uniprot id: A0A1Z2XSC9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1796620:ADH66 RS13380
gene id: 1796620:ADH66_RS13380
uniprot id: A0A1Z2XSX6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1796620:ADH66 RS01865
gene id: 1796620:ADH66_RS01865
uniprot id: A0A1Z2XM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1796620:ADH66 RS05070
gene id: 1796620:ADH66_RS05070
uniprot id: A0A1Z2XNR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1796620:ADH66 RS01915
gene id: 1796620:ADH66_RS01915
uniprot id: A0A1Z2XM61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1796620:ADH66 RS18305
gene id: 1796620:ADH66_RS18305
uniprot id: A0A1Z2XVF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796620:ADH66 RS05305
gene id: 1796620:ADH66_RS05305
uniprot id: A0A1Z2XNW4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS07475
gene id: 1796620:ADH66_RS07475
uniprot id: A0A1Z2XPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1796620:ADH66 RS06000
gene id: 1796620:ADH66_RS06000
uniprot id: A0A1Z2XP78
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796620:ADH66 RS05390
gene id: 1796620:ADH66_RS05390
uniprot id: A0A1Z2XP72
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1796620:ADH66 RS01860
gene id: 1796620:ADH66_RS01860
uniprot id: A0A1Z2XM63
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS12310
gene id: 1796620:ADH66_RS12310
uniprot id: A0A1Z2XSE2
names: Similarity
messages: Belongs to the CdaR family.

1796620:ADH66 RS08735
gene id: 1796620:ADH66_RS08735
uniprot id: A0A1Z2XQJ8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1796620:ADH66 RS13250
gene id: 1796620:ADH66_RS13250
uniprot id: A0A1Z2XSV0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1796620:ADH66 RS06400
gene id: 1796620:ADH66_RS06400
uniprot id: A0A1Z2XPF2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1796620:ADH66 RS08050
gene id: 1796620:ADH66_RS08050
uniprot id: A0A1Z2XQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1796620:ADH66 RS00360
gene id: 1796620:ADH66_RS00360
uniprot id: A0A1Z2XLC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1796620:ADH66 RS16275
gene id: 1796620:ADH66_RS16275
uniprot id: A0A1Z2XUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1796620:ADH66 RS15560
gene id: 1796620:ADH66_RS15560
uniprot id: A0A1Z2XU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS00305
gene id: 1796620:ADH66_RS00305
uniprot id: A0A1Z2XLC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1796620:ADH66 RS04395
gene id: 1796620:ADH66_RS04395
uniprot id: A0A1Z2XND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1796620:ADH66 RS03045
gene id: 1796620:ADH66_RS03045
uniprot id: A0A1Z2XMQ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1796620:ADH66 RS07570
gene id: 1796620:ADH66_RS07570
uniprot id: A0A1Z2XQ26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796620:ADH66 RS00665
gene id: 1796620:ADH66_RS00665
uniprot id: A0A1Z2XLI4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1796620:ADH66 RS19525
gene id: 1796620:ADH66_RS19525
uniprot id: A0A1Z2XW51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1796620:ADH66 RS04330
gene id: 1796620:ADH66_RS04330
uniprot id: A0A1Z2XNE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1796620:ADH66 RS12440
gene id: 1796620:ADH66_RS12440
uniprot id: A0A1Z2XSH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1796620:ADH66 RS19475
gene id: 1796620:ADH66_RS19475
uniprot id: A0A1Z2XW26
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1796620:ADH66 RS05485
gene id: 1796620:ADH66_RS05485
uniprot id: A0A1Z2XP00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1796620:ADH66 RS14840
gene id: 1796620:ADH66_RS14840
uniprot id: A0A1Z2XTN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1796620:ADH66 RS05975
gene id: 1796620:ADH66_RS05975
uniprot id: A0A1Z2XP73
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1796620:ADH66 RS10855
gene id: 1796620:ADH66_RS10855
uniprot id: A0A1Z2XRM3
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS10270
gene id: 1796620:ADH66_RS10270
uniprot id: A0A1Z2XRC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS18300
gene id: 1796620:ADH66_RS18300
uniprot id: A0A1Z2XVE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796620:ADH66 RS14255
gene id: 1796620:ADH66_RS14255
uniprot id: A0A1Z2XTE1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1796620:ADH66 RS13360
gene id: 1796620:ADH66_RS13360
uniprot id: A0A1Z2XSY0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1796620:ADH66 RS14425
gene id: 1796620:ADH66_RS14425
uniprot id: A0A1Z2XWE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1796620:ADH66 RS10250
gene id: 1796620:ADH66_RS10250
uniprot id: A0A1Z2XRE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1796620:ADH66 RS04230
gene id: 1796620:ADH66_RS04230
uniprot id: A0A1Z2XNC4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1796620:ADH66 RS19375
gene id: 1796620:ADH66_RS19375
uniprot id: A0A1Z2XVY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS13110
gene id: 1796620:ADH66_RS13110
uniprot id: A0A1Z2XST2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1796620:ADH66 RS15015
gene id: 1796620:ADH66_RS15015
uniprot id: A0A1Z2XTX9
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS18230
gene id: 1796620:ADH66_RS18230
uniprot id: A0A1Z2XVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1796620:ADH66 RS14910
gene id: 1796620:ADH66_RS14910
uniprot id: A0A1Z2XTR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1796620:ADH66 RS03980
gene id: 1796620:ADH66_RS03980
uniprot id: A0A1Z2XN65
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1796620:ADH66 RS01515
gene id: 1796620:ADH66_RS01515
uniprot id: A0A1Z2XLZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1796620:ADH66 RS11460
gene id: 1796620:ADH66_RS11460
uniprot id: A0A1Z2XRY0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1796620:ADH66 RS00195
gene id: 1796620:ADH66_RS00195
uniprot id: A0A1Z2XLA1
names: Similarity
messages: Belongs to the fabD family.

1796620:ADH66 RS17690
gene id: 1796620:ADH66_RS17690
uniprot id: A0A1Z2XV55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1796620:ADH66 RS10330
gene id: 1796620:ADH66_RS10330
uniprot id: A0A1Z2XRF6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1796620:ADH66 RS09045
gene id: 1796620:ADH66_RS09045
uniprot id: A0A1Z2XQR2
names: Similarity
messages: Belongs to the threonine synthase family.

1796620:ADH66 RS14730
gene id: 1796620:ADH66_RS14730
uniprot id: A0A1Z2XTL3
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS10105
gene id: 1796620:ADH66_RS10105
uniprot id: A0A1Z2XR96
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1796620:ADH66 RS08295
gene id: 1796620:ADH66_RS08295
uniprot id: A0A1Z2XQH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1796620:ADH66 RS02855
gene id: 1796620:ADH66_RS02855
uniprot id: A0A1Z2XMR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1796620:ADH66 RS17740
gene id: 1796620:ADH66_RS17740
uniprot id: A0A1Z2XV96
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1796620:ADH66 RS14960
gene id: 1796620:ADH66_RS14960
uniprot id: A0A1Z2XTX1
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1796620:ADH66 RS12185
gene id: 1796620:ADH66_RS12185
uniprot id: A0A1Z2XSB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1796620:ADH66 RS03345
gene id: 1796620:ADH66_RS03345
uniprot id: A0A1Z2XMW5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS10180
gene id: 1796620:ADH66_RS10180
uniprot id: A0A1Z2XRD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1796620:ADH66 RS16355
gene id: 1796620:ADH66_RS16355
uniprot id: A0A1Z2XUH8
names: Similarity
messages: Belongs to the peptidase U62 family.

1796620:ADH66 RS18290
gene id: 1796620:ADH66_RS18290
uniprot id: A0A1Z2XVG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796620:ADH66 RS08205
gene id: 1796620:ADH66_RS08205
uniprot id: A0A1Z2XQF3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796620:ADH66 RS11530
gene id: 1796620:ADH66_RS11530
uniprot id: A0A1Z2XS10
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS02135
gene id: 1796620:ADH66_RS02135
uniprot id: A0A1Z2XM94
names: Similarity
messages: Belongs to the peptidase C59 family.

1796620:ADH66 RS18455
gene id: 1796620:ADH66_RS18455
uniprot id: A0A1Z2XVI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1796620:ADH66 RS13835
gene id: 1796620:ADH66_RS13835
uniprot id: A0A1Z2XT55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1796620:ADH66 RS00825
gene id: 1796620:ADH66_RS00825
uniprot id: A0A1Z2XLL7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1796620:ADH66 RS02325
gene id: 1796620:ADH66_RS02325
uniprot id: A0A1Z2XMD3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1796620:ADH66 RS11270
gene id: 1796620:ADH66_RS11270
uniprot id: A0A1Z2XRY7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS03925
gene id: 1796620:ADH66_RS03925
uniprot id: A0A1Z2XN55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1796620:ADH66 RS06415
gene id: 1796620:ADH66_RS06415
uniprot id: A0A1Z2XPG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1796620:ADH66 RS05720
gene id: 1796620:ADH66_RS05720
uniprot id: A0A1Z2XP30
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS11635
gene id: 1796620:ADH66_RS11635
uniprot id: A0A1Z2XSA6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS11775
gene id: 1796620:ADH66_RS11775
uniprot id: A0A1Z2XS51
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1796620:ADH66 RS04500
gene id: 1796620:ADH66_RS04500
uniprot id: A0A1Z2XNK1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796620:ADH66 RS02960
gene id: 1796620:ADH66_RS02960
uniprot id: A0A1Z2XMP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS07800
gene id: 1796620:ADH66_RS07800
uniprot id: A0A1Z2XQ57
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS02835
gene id: 1796620:ADH66_RS02835
uniprot id: A0A1Z2XML5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1796620:ADH66 RS02950
gene id: 1796620:ADH66_RS02950
uniprot id: A0A1Z2XMN8
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS01625
gene id: 1796620:ADH66_RS01625
uniprot id: A0A1Z2XM03
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1796620:ADH66 RS15500
gene id: 1796620:ADH66_RS15500
uniprot id: A0A1Z2XU15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796620:ADH66 RS00595
gene id: 1796620:ADH66_RS00595
uniprot id: A0A1Z2XLH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1796620:ADH66 RS01385
gene id: 1796620:ADH66_RS01385
uniprot id: A0A1Z2XLV5
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS08535
gene id: 1796620:ADH66_RS08535
uniprot id: A0A1Z2XQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1796620:ADH66 RS04210
gene id: 1796620:ADH66_RS04210
uniprot id: A0A1Z2XNB1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1796620:ADH66 RS15620
gene id: 1796620:ADH66_RS15620
uniprot id: A0A1Z2XU22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1796620:ADH66 RS09395
gene id: 1796620:ADH66_RS09395
uniprot id: A0A1Z2XR00
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS01910
gene id: 1796620:ADH66_RS01910
uniprot id: A0A1Z2XM49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1796620:ADH66 RS04920
gene id: 1796620:ADH66_RS04920
uniprot id: A0A1Z2XNN8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1796620:ADH66 RS16610
gene id: 1796620:ADH66_RS16610
uniprot id: A0A1Z2XUQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1796620:ADH66 RS15810
gene id: 1796620:ADH66_RS15810
uniprot id: A0A1Z2XU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS10865
gene id: 1796620:ADH66_RS10865
uniprot id: A0A1Z2XRP9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS02675
gene id: 1796620:ADH66_RS02675
uniprot id: A0A1Z2XMJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1796620:ADH66 RS00220
gene id: 1796620:ADH66_RS00220
uniprot id: A0A1Z2XLA2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1796620:ADH66 RS01725
gene id: 1796620:ADH66_RS01725
uniprot id: A0A1Z2XM29
names: Similarity
messages: Belongs to the IMPACT family.

1796620:ADH66 RS02930
gene id: 1796620:ADH66_RS02930
uniprot id: A0A1Z2XMN0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1796620:ADH66 RS16010
gene id: 1796620:ADH66_RS16010
uniprot id: A0A1Z2XUB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS01735
gene id: 1796620:ADH66_RS01735
uniprot id: A0A1Z2XM18
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1796620:ADH66 RS17505
gene id: 1796620:ADH66_RS17505
uniprot id: A0A1Z2XV29
names: Similarity
messages: Belongs to the peptidase M18 family.

1796620:ADH66 RS13735
gene id: 1796620:ADH66_RS13735
uniprot id: A0A1Z2XT48
names: Similarity
messages: Belongs to the citrate synthase family.

1796620:ADH66 RS08810
gene id: 1796620:ADH66_RS08810
uniprot id: A0A1Z2XQP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS14030
gene id: 1796620:ADH66_RS14030
uniprot id: A0A1Z2XTF6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1796620:ADH66 RS11385
gene id: 1796620:ADH66_RS11385
uniprot id: A0A1Z2XWE1
names: Similarity
messages: Belongs to the class-I fumarase family.

1796620:ADH66 RS11655
gene id: 1796620:ADH66_RS11655
uniprot id: A0A1Z2XWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1796620:ADH66 RS08995
gene id: 1796620:ADH66_RS08995
uniprot id: A0A1Z2XQP4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1796620:ADH66 RS00455
gene id: 1796620:ADH66_RS00455
uniprot id: A0A1Z2XLF1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1796620:ADH66 RS02145
gene id: 1796620:ADH66_RS02145
uniprot id: A0A1Z2XMA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1796620:ADH66 RS13340
gene id: 1796620:ADH66_RS13340
uniprot id: A0A1Z2XT16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1796620:ADH66 RS08695
gene id: 1796620:ADH66_RS08695
uniprot id: A0A1Z2XQM2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1796620:ADH66 RS18295
gene id: 1796620:ADH66_RS18295
uniprot id: A0A1Z2XVG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796620:ADH66 RS08480
gene id: 1796620:ADH66_RS08480
uniprot id: A0A1Z2XQF4
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1796620:ADH66 RS14115
gene id: 1796620:ADH66_RS14115
uniprot id: A0A1Z2XTG7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1796620:ADH66 RS02385
gene id: 1796620:ADH66_RS02385
uniprot id: A0A1Z2XMD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796620:ADH66 RS18500
gene id: 1796620:ADH66_RS18500
uniprot id: A0A1Z2XVM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1796620:ADH66 RS18005
gene id: 1796620:ADH66_RS18005
uniprot id: A0A1Z2XVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1796620:ADH66 RS00180
gene id: 1796620:ADH66_RS00180
uniprot id: A0A1Z2XL87
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1796620:ADH66 RS04955
gene id: 1796620:ADH66_RS04955
uniprot id: A0A1Z2XNQ1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1796620:ADH66 RS09990
gene id: 1796620:ADH66_RS09990
uniprot id: A0A1Z2XRA5
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS15845
gene id: 1796620:ADH66_RS15845
uniprot id: A0A1Z2XUC7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS16045
gene id: 1796620:ADH66_RS16045
uniprot id: A0A1Z2XUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS08955
gene id: 1796620:ADH66_RS08955
uniprot id: A0A1Z2XQP5
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1796620:ADH66 RS04825
gene id: 1796620:ADH66_RS04825
uniprot id: A0A1Z2XNL9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS03885
gene id: 1796620:ADH66_RS03885
uniprot id: A0A1Z2XN47
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1796620:ADH66 RS16570
gene id: 1796620:ADH66_RS16570
uniprot id: A0A1Z2XWJ1
names: Similarity
messages: Belongs to the asparaginase 1 family.

1796620:ADH66 RS10300
gene id: 1796620:ADH66_RS10300
uniprot id: A0A1Z2XRF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1796620:ADH66 RS15685
gene id: 1796620:ADH66_RS15685
uniprot id: A0A1Z2XU33
names: Similarity
messages: Belongs to the thymidylate kinase family.

1796620:ADH66 RS13430
gene id: 1796620:ADH66_RS13430
uniprot id: A0A1Z2XSZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1796620:ADH66 RS11470
gene id: 1796620:ADH66_RS11470
uniprot id: A0A1Z2XS22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1796620:ADH66 RS00955
gene id: 1796620:ADH66_RS00955
uniprot id: A0A1Z2XLP3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1796620:ADH66 RS02395
gene id: 1796620:ADH66_RS02395
uniprot id: A0A1Z2XMD1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1796620:ADH66 RS13985
gene id: 1796620:ADH66_RS13985
uniprot id: A0A1Z2XWG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1796620:ADH66 RS15655
gene id: 1796620:ADH66_RS15655
uniprot id: A0A1Z2XU44
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1796620:ADH66 RS06155
gene id: 1796620:ADH66_RS06155
uniprot id: A0A1Z2XPB6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS18460
gene id: 1796620:ADH66_RS18460
uniprot id: A0A1Z2XVJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1796620:ADH66 RS13310
gene id: 1796620:ADH66_RS13310
uniprot id: A0A1Z2XSV7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1796620:ADH66 RS14480
gene id: 1796620:ADH66_RS14480
uniprot id: A0A1Z2XTH2
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1796620:ADH66 RS02650
gene id: 1796620:ADH66_RS02650
uniprot id: A0A1Z2XMI0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1796620:ADH66 RS11455
gene id: 1796620:ADH66_RS11455
uniprot id: A0A1Z2XRY1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1796620:ADH66 RS02595
gene id: 1796620:ADH66_RS02595
uniprot id: A0A1Z2XMI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1796620:ADH66 RS12145
gene id: 1796620:ADH66_RS12145
uniprot id: A0A1Z2XSJ4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1796620:ADH66 RS11860
gene id: 1796620:ADH66_RS11860
uniprot id: A0A1Z2XSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS01465
gene id: 1796620:ADH66_RS01465
uniprot id: A0A1Z2XLY2
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS13495
gene id: 1796620:ADH66_RS13495
uniprot id: A0A1Z2XT53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1796620:ADH66 RS04520
gene id: 1796620:ADH66_RS04520
uniprot id: A0A1Z2XNH0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS01880
gene id: 1796620:ADH66_RS01880
uniprot id: A0A1Z2XM57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1796620:ADH66 RS09360
gene id: 1796620:ADH66_RS09360
uniprot id: A0A1Z2XQX7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1796620:ADH66 RS03690
gene id: 1796620:ADH66_RS03690
uniprot id: A0A1Z2XMZ9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1796620:ADH66 RS09055
gene id: 1796620:ADH66_RS09055
uniprot id: A0A1Z2XQU4
names: Similarity
messages: Belongs to the UPF0102 family.

1796620:ADH66 RS02530
gene id: 1796620:ADH66_RS02530
uniprot id: A0A1Z2XMH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1796620:ADH66 RS02170
gene id: 1796620:ADH66_RS02170
uniprot id: A0A1Z2XMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796620:ADH66 RS13565
gene id: 1796620:ADH66_RS13565
uniprot id: A0A1Z2XT19
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1796620:ADH66 RS06395
gene id: 1796620:ADH66_RS06395
uniprot id: A0A1Z2XPE8
names: Similarity
messages: Belongs to the SfsA family.

1796620:ADH66 RS02380
gene id: 1796620:ADH66_RS02380
uniprot id: A0A1Z2XME5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1796620:ADH66 RS01535
gene id: 1796620:ADH66_RS01535
uniprot id: A0A1Z2XLY5
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1796620:ADH66 RS01930
gene id: 1796620:ADH66_RS01930
uniprot id: A0A1Z2XM60
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1796620:ADH66 RS04640
gene id: 1796620:ADH66_RS04640
uniprot id: A0A1Z2XNI1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1796620:ADH66 RS05180
gene id: 1796620:ADH66_RS05180
uniprot id: A0A1Z2XNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS18375
gene id: 1796620:ADH66_RS18375
uniprot id: A0A1Z2XVG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1796620:ADH66 RS01940
gene id: 1796620:ADH66_RS01940
uniprot id: A0A1Z2XM59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1796620:ADH66 RS11015
gene id: 1796620:ADH66_RS11015
uniprot id: A0A1Z2XRZ8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS08555
gene id: 1796620:ADH66_RS08555
uniprot id: A0A1Z2XQM3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1796620:ADH66 RS06600
gene id: 1796620:ADH66_RS06600
uniprot id: A0A1Z2XPI5
names: Similarity
messages: Belongs to the RemA family.

1796620:ADH66 RS17090
gene id: 1796620:ADH66_RS17090
uniprot id: A0A1Z2XV13
names: Similarity
messages: Belongs to the UPF0246 family.

1796620:ADH66 RS13670
gene id: 1796620:ADH66_RS13670
uniprot id: A0A1Z2XT38
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1796620:ADH66 RS01640
gene id: 1796620:ADH66_RS01640
uniprot id: A0A1Z2XM06
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

1796620:ADH66 RS11095
gene id: 1796620:ADH66_RS11095
uniprot id: A0A1Z2XRT6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796620:ADH66 RS19550
gene id: 1796620:ADH66_RS19550
uniprot id: A0A1Z2XW40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1796620:ADH66 RS12770
gene id: 1796620:ADH66_RS12770
uniprot id: A0A1Z2XSN2
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1796620:ADH66 RS09145
gene id: 1796620:ADH66_RS09145
uniprot id: A0A1Z2XQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1796620:ADH66 RS11910
gene id: 1796620:ADH66_RS11910
uniprot id: A0A1Z2XSF3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS08245
gene id: 1796620:ADH66_RS08245
uniprot id: A0A1Z2XQG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS04490
gene id: 1796620:ADH66_RS04490
uniprot id: A0A1Z2XNF9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1796620:ADH66 RS00620
gene id: 1796620:ADH66_RS00620
uniprot id: A0A1Z2XLH7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1796620:ADH66 RS16150
gene id: 1796620:ADH66_RS16150
uniprot id: A0A1Z2XUE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1796620:ADH66 RS00255
gene id: 1796620:ADH66_RS00255
uniprot id: A0A1Z2XLA8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1796620:ADH66 RS13295
gene id: 1796620:ADH66_RS13295
uniprot id: A0A1Z2XSV4
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1796620:ADH66 RS12270
gene id: 1796620:ADH66_RS12270
uniprot id: A0A1Z2XSG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1796620:ADH66 RS07540
gene id: 1796620:ADH66_RS07540
uniprot id: A0A1Z2XQ12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1796620:ADH66 RS08915
gene id: 1796620:ADH66_RS08915
uniprot id: A0A1Z2XQM8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS09730
gene id: 1796620:ADH66_RS09730
uniprot id: A0A1Z2XR87
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796620:ADH66 RS01485
gene id: 1796620:ADH66_RS01485
uniprot id: A0A1Z2XLX3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1796620:ADH66 RS06620
gene id: 1796620:ADH66_RS06620
uniprot id: A0A1Z2XPJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1796620:ADH66 RS18430
gene id: 1796620:ADH66_RS18430
uniprot id: A0A1Z2XWJ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1796620:ADH66 RS10580
gene id: 1796620:ADH66_RS10580
uniprot id: A0A1Z2XRQ9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1796620:ADH66 RS00700
gene id: 1796620:ADH66_RS00700
uniprot id: A0A1Z2XLK3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS02580
gene id: 1796620:ADH66_RS02580
uniprot id: A0A1Z2XMI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1796620:ADH66 RS06115
gene id: 1796620:ADH66_RS06115
uniprot id: A0A1Z2XPA3
names: Similarity
messages: Belongs to the plasmid mobilization pre family.

1796620:ADH66 RS11560
gene id: 1796620:ADH66_RS11560
uniprot id: A0A1Z2XRZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1796620:ADH66 RS13230
gene id: 1796620:ADH66_RS13230
uniprot id: A0A1Z2XSX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS02115
gene id: 1796620:ADH66_RS02115
uniprot id: A0A1Z2XM86
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796620:ADH66 RS01960
gene id: 1796620:ADH66_RS01960
uniprot id: A0A1Z2XM58
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1796620:ADH66 RS14090
gene id: 1796620:ADH66_RS14090
uniprot id: A0A1Z2XTD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1796620:ADH66 RS02795
gene id: 1796620:ADH66_RS02795
uniprot id: A0A1Z2XML9
names: Similarity
messages: Belongs to the EamA transporter family.

1796620:ADH66 RS18410
gene id: 1796620:ADH66_RS18410
uniprot id: A0A1Z2XVG5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1796620:ADH66 RS04560
gene id: 1796620:ADH66_RS04560
uniprot id: A0A1Z2XNH8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS13305
gene id: 1796620:ADH66_RS13305
uniprot id: A0A1Z2XSX0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1796620:ADH66 RS07875
gene id: 1796620:ADH66_RS07875
uniprot id: A0A1Z2XQ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS00935
gene id: 1796620:ADH66_RS00935
uniprot id: A0A1Z2XLN4
names: Similarity
messages: Belongs to the UPF0246 family.

1796620:ADH66 RS16295
gene id: 1796620:ADH66_RS16295
uniprot id: A0A1Z2XUG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1796620:ADH66 RS12430
gene id: 1796620:ADH66_RS12430
uniprot id: A0A1Z2XSP2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1796620:ADH66 RS05310
gene id: 1796620:ADH66_RS05310
uniprot id: A0A1Z2XNW0
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1796620:ADH66 RS01825
gene id: 1796620:ADH66_RS01825
uniprot id: A0A1Z2XM47
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS16350
gene id: 1796620:ADH66_RS16350
uniprot id: A0A1Z2XUH5
names: Similarity
messages: Belongs to the peptidase U62 family.

1796620:ADH66 RS10505
gene id: 1796620:ADH66_RS10505
uniprot id: A0A1Z2XRG7
names: Similarity
messages: Belongs to the peptidase S14 family.

1796620:ADH66 RS10375
gene id: 1796620:ADH66_RS10375
uniprot id: A0A1Z2XRE3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS03595
gene id: 1796620:ADH66_RS03595
uniprot id: A0A1Z2XN03
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS18675
gene id: 1796620:ADH66_RS18675
uniprot id: A0A1Z2XVN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS10140
gene id: 1796620:ADH66_RS10140
uniprot id: A0A1Z2XRG0
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS18480
gene id: 1796620:ADH66_RS18480
uniprot id: A0A1Z2XVH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1796620:ADH66 RS17365
gene id: 1796620:ADH66_RS17365
uniprot id: A0A1Z2XV05
names: Similarity
messages: Belongs to the DtxR/MntR family.

1796620:ADH66 RS04025
gene id: 1796620:ADH66_RS04025
uniprot id: A0A1Z2XN62
names: Similarity
messages: Belongs to the EamA transporter family.

1796620:ADH66 RS18650
gene id: 1796620:ADH66_RS18650
uniprot id: A0A1Z2XVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1796620:ADH66 RS01680
gene id: 1796620:ADH66_RS01680
uniprot id: A0A1Z2XM10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1796620:ADH66 RS01685
gene id: 1796620:ADH66_RS01685
uniprot id: A0A1Z2XM22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1796620:ADH66 RS15565
gene id: 1796620:ADH66_RS15565
uniprot id: A0A1Z2XU12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS08390
gene id: 1796620:ADH66_RS08390
uniprot id: A0A1Z2XQG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1796620:ADH66 RS14150
gene id: 1796620:ADH66_RS14150
uniprot id: A0A1Z2XTB7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1796620:ADH66 RS08200
gene id: 1796620:ADH66_RS08200
uniprot id: A0A1Z2XQB1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796620:ADH66 RS18395
gene id: 1796620:ADH66_RS18395
uniprot id: A0A1Z2XVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1796620:ADH66 RS15895
gene id: 1796620:ADH66_RS15895
uniprot id: A0A1Z2XWI6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1796620:ADH66 RS13905
gene id: 1796620:ADH66_RS13905
uniprot id: A0A1Z2XTC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1796620:ADH66 RS05295
gene id: 1796620:ADH66_RS05295
uniprot id: A0A1Z2XNW2
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS11415
gene id: 1796620:ADH66_RS11415
uniprot id: A0A1Z2XRY5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1796620:ADH66 RS18535
gene id: 1796620:ADH66_RS18535
uniprot id: A0A1Z2XVJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1796620:ADH66 RS18425
gene id: 1796620:ADH66_RS18425
uniprot id: A0A1Z2XVH1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1796620:ADH66 RS17155
gene id: 1796620:ADH66_RS17155
uniprot id: A0A1Z2XV17
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1796620:ADH66 RS03555
gene id: 1796620:ADH66_RS03555
uniprot id: A0A1Z2XMY8
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS00900
gene id: 1796620:ADH66_RS00900
uniprot id: A0A1Z2XLP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1796620:ADH66 RS05020
gene id: 1796620:ADH66_RS05020
uniprot id: A0A1Z2XNR7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1796620:ADH66 RS08155
gene id: 1796620:ADH66_RS08155
uniprot id: A0A1Z2XQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS02685
gene id: 1796620:ADH66_RS02685
uniprot id: A0A1Z2XMN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS06375
gene id: 1796620:ADH66_RS06375
uniprot id: A0A1Z2XPE5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1796620:ADH66 RS04260
gene id: 1796620:ADH66_RS04260
uniprot id: A0A1Z2XNB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS10070
gene id: 1796620:ADH66_RS10070
uniprot id: A0A1Z2XRB7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS18240
gene id: 1796620:ADH66_RS18240
uniprot id: A0A1Z2XVD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1796620:ADH66 RS04695
gene id: 1796620:ADH66_RS04695
uniprot id: A0A1Z2XNL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1796620:ADH66 RS08425
gene id: 1796620:ADH66_RS08425
uniprot id: A0A1Z2XW97
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1796620:ADH66 RS07345
gene id: 1796620:ADH66_RS07345
uniprot id: A0A1Z2XPW9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1796620:ADH66 RS14685
gene id: 1796620:ADH66_RS14685
uniprot id: A0A1Z2XTT6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS02940
gene id: 1796620:ADH66_RS02940
uniprot id: A0A1Z2XMS1
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1796620:ADH66 RS15925
gene id: 1796620:ADH66_RS15925
uniprot id: A0A1Z2XUC5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1796620:ADH66 RS10400
gene id: 1796620:ADH66_RS10400
uniprot id: A0A1Z2XRF3
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1796620:ADH66 RS04360
gene id: 1796620:ADH66_RS04360
uniprot id: A0A1Z2XND3
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS13270
gene id: 1796620:ADH66_RS13270
uniprot id: A0A1Z2XSW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS08750
gene id: 1796620:ADH66_RS08750
uniprot id: A0A1Z2XQN2
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1796620:ADH66 RS17860
gene id: 1796620:ADH66_RS17860
uniprot id: A0A1Z2XV91
names: Subcellular Location Annotation
messages: Cytoplasm

1796620:ADH66 RS02995
gene id: 1796620:ADH66_RS02995
uniprot id: A0A1Z2XMQ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1796620:ADH66 RS13405
gene id: 1796620:ADH66_RS13405
uniprot id: A0A1Z2XT40
names: Subcellular Location Annotation
messages: Cytoplasm

1796620:ADH66 RS02555
gene id: 1796620:ADH66_RS02555
uniprot id: A0A1Z2XMI5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1796620:ADH66 RS14260
gene id: 1796620:ADH66_RS14260
uniprot id: A0A1Z2XTF8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1796620:ADH66 RS09705
gene id: 1796620:ADH66_RS09705
uniprot id: A0A1Z2XR32
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1796620:ADH66 RS14010
gene id: 1796620:ADH66_RS14010
uniprot id: A0A1Z2XTE2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS13900
gene id: 1796620:ADH66_RS13900
uniprot id: A0A1Z2XT77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1796620:ADH66 RS10240
gene id: 1796620:ADH66_RS10240
uniprot id: A0A1Z2XRC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1796620:ADH66 RS18155
gene id: 1796620:ADH66_RS18155
uniprot id: A0A1Z2XVC5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS09600
gene id: 1796620:ADH66_RS09600
uniprot id: A0A1Z2XR29
names: Similarity
messages: Belongs to the 'phage' integrase family.

1796620:ADH66 RS00820
gene id: 1796620:ADH66_RS00820
uniprot id: A0A1Z2XLL5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1796620:ADH66 RS06470
gene id: 1796620:ADH66_RS06470
uniprot id: A0A1Z2XPG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1796620:ADH66 RS09120
gene id: 1796620:ADH66_RS09120
uniprot id: A0A1Z2XQU7
names: Similarity
messages: Belongs to the GSP E family.

1796620:ADH66 RS09340
gene id: 1796620:ADH66_RS09340
uniprot id: A0A1Z2XR22
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS01185
gene id: 1796620:ADH66_RS01185
uniprot id: A0A1Z2XLS4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1796620:ADH66 RS11865
gene id: 1796620:ADH66_RS11865
uniprot id: A0A1Z2XS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS19515
gene id: 1796620:ADH66_RS19515
uniprot id: A0A1Z2XW03
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS02210
gene id: 1796620:ADH66_RS02210
uniprot id: A0A1Z2XMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

1796620:ADH66 RS16170
gene id: 1796620:ADH66_RS16170
uniprot id: A0A1Z2XUC4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1796620:ADH66 RS03575
gene id: 1796620:ADH66_RS03575
uniprot id: A0A1Z2XMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1796620:ADH66 RS08725
gene id: 1796620:ADH66_RS08725
uniprot id: A0A1Z2XQJ4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1796620:ADH66 RS15600
gene id: 1796620:ADH66_RS15600
uniprot id: A0A1Z2XU46
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1796620:ADH66 RS17530
gene id: 1796620:ADH66_RS17530
uniprot id: A0A1Z2XV28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1796620:ADH66 RS18350
gene id: 1796620:ADH66_RS18350
uniprot id: A0A1Z2XVH7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1796620:ADH66 RS11665
gene id: 1796620:ADH66_RS11665
uniprot id: A0A1Z2XS30
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1796620:ADH66 RS14815
gene id: 1796620:ADH66_RS14815
uniprot id: A0A1Z2XTN1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS01770
gene id: 1796620:ADH66_RS01770
uniprot id: A0A1Z2XM35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1796620:ADH66 RS01955
gene id: 1796620:ADH66_RS01955
uniprot id: A0A1Z2XM62
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1796620:ADH66 RS09200
gene id: 1796620:ADH66_RS09200
uniprot id: A0A1Z2XQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS02280
gene id: 1796620:ADH66_RS02280
uniprot id: A0A1Z2XMB4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1796620:ADH66 RS00695
gene id: 1796620:ADH66_RS00695
uniprot id: A0A1Z2XLK2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1796620:ADH66 RS11180
gene id: 1796620:ADH66_RS11180
uniprot id: A0A1Z2XRX2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1796620:ADH66 RS00370
gene id: 1796620:ADH66_RS00370
uniprot id: A0A1Z2XLE5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1796620:ADH66 RS19155
gene id: 1796620:ADH66_RS19155
uniprot id: A0A1Z2XVZ0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1796620:ADH66 RS19560
gene id: 1796620:ADH66_RS19560
uniprot id: A0A1Z2XW10
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1796620:ADH66 RS14450
gene id: 1796620:ADH66_RS14450
uniprot id: A0A1Z2XTH0
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS04120
gene id: 1796620:ADH66_RS04120
uniprot id: A0A1Z2XN89
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS08015
gene id: 1796620:ADH66_RS08015
uniprot id: A0A1Z2XQC9
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS11645
gene id: 1796620:ADH66_RS11645
uniprot id: A0A1Z2XS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1796620:ADH66 RS13355
gene id: 1796620:ADH66_RS13355
uniprot id: A0A1Z2XSW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1796620:ADH66 RS05450
gene id: 1796620:ADH66_RS05450
uniprot id: A0A1Z2XNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS06735
gene id: 1796620:ADH66_RS06735
uniprot id: A0A1Z2XPK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1796620:ADH66 RS00150
gene id: 1796620:ADH66_RS00150
uniprot id: A0A1Z2XLB1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1796620:ADH66 RS19290
gene id: 1796620:ADH66_RS19290
uniprot id: A0A1Z2XVZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1796620:ADH66 RS04710
gene id: 1796620:ADH66_RS04710
uniprot id: A0A1Z2XNL2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1796620:ADH66 RS00325
gene id: 1796620:ADH66_RS00325
uniprot id: A0A1Z2XLB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1796620:ADH66 RS07430
gene id: 1796620:ADH66_RS07430
uniprot id: A0A1Z2XQ31
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS00920
gene id: 1796620:ADH66_RS00920
uniprot id: A0A1Z2XLN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1796620:ADH66 RS00505
gene id: 1796620:ADH66_RS00505
uniprot id: A0A1Z2XLF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1796620:ADH66 RS19390
gene id: 1796620:ADH66_RS19390
uniprot id: A0A1Z2XVZ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1796620:ADH66 RS11475
gene id: 1796620:ADH66_RS11475
uniprot id: A0A1Z2XS77
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS14250
gene id: 1796620:ADH66_RS14250
uniprot id: A0A1Z2XTK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1796620:ADH66 RS18445
gene id: 1796620:ADH66_RS18445
uniprot id: A0A1Z2XVI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1796620:ADH66 RS10345
gene id: 1796620:ADH66_RS10345
uniprot id: A0A1Z2XRE7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1796620:ADH66 RS09510
gene id: 1796620:ADH66_RS09510
uniprot id: A0A1Z2XR48
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS02175
gene id: 1796620:ADH66_RS02175
uniprot id: A0A1Z2XM98
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1796620:ADH66 RS01255
gene id: 1796620:ADH66_RS01255
uniprot id: A0A1Z2XLT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1796620:ADH66 RS04100
gene id: 1796620:ADH66_RS04100
uniprot id: A0A1Z2XNA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1796620:ADH66 RS05455
gene id: 1796620:ADH66_RS05455
uniprot id: A0A1Z2XP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS00720
gene id: 1796620:ADH66_RS00720
uniprot id: A0A1Z2XLJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1796620:ADH66 RS06695
gene id: 1796620:ADH66_RS06695
uniprot id: A0A1Z2XPN9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1796620:ADH66 RS05095
gene id: 1796620:ADH66_RS05095
uniprot id: A0A1Z2XNW7
names: Function
names: Similarity
messages: Belongs to the hemerythrin family.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS17905
gene id: 1796620:ADH66_RS17905
uniprot id: A0A1Z2XVC9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1796620:ADH66 RS00040
gene id: 1796620:ADH66_RS00040
uniprot id: A0A1Z2XL68
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1796620:ADH66 RS11285
gene id: 1796620:ADH66_RS11285
uniprot id: A0A1Z2XRV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1796620:ADH66 RS17130
gene id: 1796620:ADH66_RS17130
uniprot id: A0A1Z2XUV0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1796620:ADH66 RS18495
gene id: 1796620:ADH66_RS18495
uniprot id: A0A1Z2XVJ2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1796620:ADH66 RS01460
gene id: 1796620:ADH66_RS01460
uniprot id: A0A1Z2XLY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1796620:ADH66 RS14455
gene id: 1796620:ADH66_RS14455
uniprot id: A0A1Z2XTI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS04655
gene id: 1796620:ADH66_RS04655
uniprot id: A0A1Z2XNI9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS01530
gene id: 1796620:ADH66_RS01530
uniprot id: A0A1Z2XLY7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796620:ADH66 RS06610
gene id: 1796620:ADH66_RS06610
uniprot id: A0A1Z2XPI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1796620:ADH66 RS01775
gene id: 1796620:ADH66_RS01775
uniprot id: A0A1Z2XM42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1796620:ADH66 RS06475
gene id: 1796620:ADH66_RS06475
uniprot id: A0A1Z2XPG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1796620:ADH66 RS14850
gene id: 1796620:ADH66_RS14850
uniprot id: A0A1Z2XTR4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1796620:ADH66 RS10325
gene id: 1796620:ADH66_RS10325
uniprot id: A0A1Z2XRE5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1796620:ADH66 RS18685
gene id: 1796620:ADH66_RS18685
uniprot id: A0A1Z2XVM5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1796620:ADH66 RS04340
gene id: 1796620:ADH66_RS04340
uniprot id: A0A1Z2XND9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1796620:ADH66 RS00035
gene id: 1796620:ADH66_RS00035
uniprot id: A0A1Z2XW07
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1796620:ADH66 RS18560
gene id: 1796620:ADH66_RS18560
uniprot id: A0A1Z2XVN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1796620:ADH66 RS12165
gene id: 1796620:ADH66_RS12165
uniprot id: A0A1Z2XSE7
names: Similarity
messages: Belongs to the UPF0473 family.

1796620:ADH66 RS04625
gene id: 1796620:ADH66_RS04625
uniprot id: A0A1Z2XNI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1796620:ADH66 RS15790
gene id: 1796620:ADH66_RS15790
uniprot id: A0A1Z2XU59
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS15695
gene id: 1796620:ADH66_RS15695
uniprot id: A0A1Z2XU68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1796620:ADH66 RS00540
gene id: 1796620:ADH66_RS00540
uniprot id: A0A1Z2XW20
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1796620:ADH66 RS01265
gene id: 1796620:ADH66_RS01265
uniprot id: A0A1Z2XLT9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1796620:ADH66 RS11660
gene id: 1796620:ADH66_RS11660
uniprot id: A0A1Z2XS57
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS09100
gene id: 1796620:ADH66_RS09100
uniprot id: A0A1Z2XQU1
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

1796620:ADH66 RS12065
gene id: 1796620:ADH66_RS12065
uniprot id: A0A1Z2XSF7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS01855
gene id: 1796620:ADH66_RS01855
uniprot id: A0A1Z2XM50
names: Similarity
messages: Belongs to the peptidase C1 family.

1796620:ADH66 RS02180
gene id: 1796620:ADH66_RS02180
uniprot id: A0A1Z2XMA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1796620:ADH66 RS11275
gene id: 1796620:ADH66_RS11275
uniprot id: A0A1Z2XRV9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1796620:ADH66 RS18200
gene id: 1796620:ADH66_RS18200
uniprot id: A0A1Z2XVD5
names: Similarity
messages: Belongs to the TelA family.

1796620:ADH66 RS13610
gene id: 1796620:ADH66_RS13610
uniprot id: A0A1Z2XT78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1796620:ADH66 RS13235
gene id: 1796620:ADH66_RS13235
uniprot id: A0A1Z2XT15
names: Similarity
messages: Belongs to the LOR family.

1796620:ADH66 RS09350
gene id: 1796620:ADH66_RS09350
uniprot id: A0A1Z2XQW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS02375
gene id: 1796620:ADH66_RS02375
uniprot id: A0A1Z2XMD9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1796620:ADH66 RS02315
gene id: 1796620:ADH66_RS02315
uniprot id: A0A1Z2XMC9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS14875
gene id: 1796620:ADH66_RS14875
uniprot id: A0A1Z2XTQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1796620:ADH66 RS11595
gene id: 1796620:ADH66_RS11595
uniprot id: A0A1Z2XS15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1796620:ADH66 RS17310
gene id: 1796620:ADH66_RS17310
uniprot id: A0A1Z2XV51
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796620:ADH66 RS14890
gene id: 1796620:ADH66_RS14890
uniprot id: A0A1Z2XTP2
names: Similarity
messages: Belongs to the DprA/Smf family.

1796620:ADH66 RS04460
gene id: 1796620:ADH66_RS04460
uniprot id: A0A1Z2XNF1
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS11600
gene id: 1796620:ADH66_RS11600
uniprot id: A0A1Z2XS46
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1796620:ADH66 RS04900
gene id: 1796620:ADH66_RS04900
uniprot id: A0A1Z2XNP2
names: Similarity
messages: Belongs to the CtsR family.

1796620:ADH66 RS12625
gene id: 1796620:ADH66_RS12625
uniprot id: A0A1Z2XSJ0
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS00110
gene id: 1796620:ADH66_RS00110
uniprot id: A0A1Z2XL88
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1796620:ADH66 RS13605
gene id: 1796620:ADH66_RS13605
uniprot id: A0A1Z2XT41
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1796620:ADH66 RS02105
gene id: 1796620:ADH66_RS02105
uniprot id: A0A1Z2XM91
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS06575
gene id: 1796620:ADH66_RS06575
uniprot id: A0A1Z2XPI0
names: Subcellular Location Annotation
messages: Cytoplasm

1796620:ADH66 RS06090
gene id: 1796620:ADH66_RS06090
uniprot id: A0A1Z2XP98
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1796620:ADH66 RS01435
gene id: 1796620:ADH66_RS01435
uniprot id: A0A1Z2XLW4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1796620:ADH66 RS10410
gene id: 1796620:ADH66_RS10410
uniprot id: A0A1Z2XRH1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS08525
gene id: 1796620:ADH66_RS08525
uniprot id: A0A1Z2XQH6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1796620:ADH66 RS15815
gene id: 1796620:ADH66_RS15815
uniprot id: A0A1Z2XU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS05515
gene id: 1796620:ADH66_RS05515
uniprot id: A0A1Z2XNZ6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS03855
gene id: 1796620:ADH66_RS03855
uniprot id: A0A1Z2XN40
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS16050
gene id: 1796620:ADH66_RS16050
uniprot id: A0A1Z2XUC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS18420
gene id: 1796620:ADH66_RS18420
uniprot id: A0A1Z2XVH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1796620:ADH66 RS10185
gene id: 1796620:ADH66_RS10185
uniprot id: A0A1Z2XRD6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1796620:ADH66 RS18690
gene id: 1796620:ADH66_RS18690
uniprot id: A0A1Z2XVM0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796620:ADH66 RS08020
gene id: 1796620:ADH66_RS08020
uniprot id: A0A1Z2XQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1796620:ADH66 RS14805
gene id: 1796620:ADH66_RS14805
uniprot id: A0A1Z2XTP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS03605
gene id: 1796620:ADH66_RS03605
uniprot id: A0A1Z2XN01
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS00785
gene id: 1796620:ADH66_RS00785
uniprot id: A0A1Z2XLL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1796620:ADH66 RS09590
gene id: 1796620:ADH66_RS09590
uniprot id: A0A1Z2XR10
names: Similarity
messages: Belongs to the UPF0597 family.

1796620:ADH66 RS08510
gene id: 1796620:ADH66_RS08510
uniprot id: A0A1Z2XQI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1796620:ADH66 RS09720
gene id: 1796620:ADH66_RS09720
uniprot id: A0A1Z2XR53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS19370
gene id: 1796620:ADH66_RS19370
uniprot id: A0A1Z2XVY1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS12900
gene id: 1796620:ADH66_RS12900
uniprot id: A0A1Z2XSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1796620:ADH66 RS08625
gene id: 1796620:ADH66_RS08625
uniprot id: A0A1Z2XQH7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1796620:ADH66 RS07385
gene id: 1796620:ADH66_RS07385
uniprot id: A0A1Z2XPY1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1796620:ADH66 RS01800
gene id: 1796620:ADH66_RS01800
uniprot id: A0A1Z2XM34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1796620:ADH66 RS13130
gene id: 1796620:ADH66_RS13130
uniprot id: A0A1Z2XSZ5
names: Similarity
messages: Belongs to the glutamate synthase family.

1796620:ADH66 RS04310
gene id: 1796620:ADH66_RS04310
uniprot id: A0A1Z2XNC7
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS06565
gene id: 1796620:ADH66_RS06565
uniprot id: A0A1Z2XPJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1796620:ADH66 RS04485
gene id: 1796620:ADH66_RS04485
uniprot id: A0A1Z2XNF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1796620:ADH66 RS04970
gene id: 1796620:ADH66_RS04970
uniprot id: A0A1Z2XNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS14755
gene id: 1796620:ADH66_RS14755
uniprot id: A0A1Z2XTM7
names: Similarity
messages: Belongs to the DprA/Smf family.

1796620:ADH66 RS03415
gene id: 1796620:ADH66_RS03415
uniprot id: A0A1Z2XMW7
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1796620:ADH66 RS14240
gene id: 1796620:ADH66_RS14240
uniprot id: A0A1Z2XTK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1796620:ADH66 RS15985
gene id: 1796620:ADH66_RS15985
uniprot id: A0A1Z2XUC9
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796620:ADH66 RS00205
gene id: 1796620:ADH66_RS00205
uniprot id: A0A1Z2XL98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1796620:ADH66 RS03510
gene id: 1796620:ADH66_RS03510
uniprot id: A0A1Z2XMZ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1796620:ADH66 RS16125
gene id: 1796620:ADH66_RS16125
uniprot id: A0A1Z2XUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796620:ADH66 RS11135
gene id: 1796620:ADH66_RS11135
uniprot id: A0A1Z2XRU1
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS13185
gene id: 1796620:ADH66_RS13185
uniprot id: A0A1Z2XT05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1796620:ADH66 RS18490
gene id: 1796620:ADH66_RS18490
uniprot id: A0A1Z2XVN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1796620:ADH66 RS18950
gene id: 1796620:ADH66_RS18950
uniprot id: A0A1Z2XVQ0
names: Similarity
messages: Belongs to the ParB family.

1796620:ADH66 RS16415
gene id: 1796620:ADH66_RS16415
uniprot id: A0A1Z2XUI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1796620:ADH66 RS11215
gene id: 1796620:ADH66_RS11215
uniprot id: A0A1Z2XRU9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796620:ADH66 RS13635
gene id: 1796620:ADH66_RS13635
uniprot id: A0A1Z2XT31
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1796620:ADH66 RS10685
gene id: 1796620:ADH66_RS10685
uniprot id: A0A1Z2XRG7
names: Similarity
messages: Belongs to the peptidase S14 family.

1796620:ADH66 RS18615
gene id: 1796620:ADH66_RS18615
uniprot id: A0A1Z2XVL7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1796620:ADH66 RS03315
gene id: 1796620:ADH66_RS03315
uniprot id: A0A1Z2XMV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796620:ADH66 RS14145
gene id: 1796620:ADH66_RS14145
uniprot id: A0A1Z2XTJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796620:ADH66 RS01600
gene id: 1796620:ADH66_RS01600
uniprot id: A0A1Z2XLZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1796620:ADH66 RS13765
gene id: 1796620:ADH66_RS13765
uniprot id: A0A1Z2XTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1796620:ADH66 RS00265
gene id: 1796620:ADH66_RS00265
uniprot id: A0A1Z2XW33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1796620:ADH66 RS05220
gene id: 1796620:ADH66_RS05220
uniprot id: A0A1Z2XNU2
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS06550
gene id: 1796620:ADH66_RS06550
uniprot id: A0A1Z2XPH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796620:ADH66 RS05490
gene id: 1796620:ADH66_RS05490
uniprot id: A0A1Z2XNZ4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1796620:ADH66 RS10255
gene id: 1796620:ADH66_RS10255
uniprot id: A0A1Z2XWA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1796620:ADH66 RS02815
gene id: 1796620:ADH66_RS02815
uniprot id: A0A1Z2XML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1796620:ADH66 RS06545
gene id: 1796620:ADH66_RS06545
uniprot id: A0A1Z2XPI3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1796620:ADH66 RS17805
gene id: 1796620:ADH66_RS17805
uniprot id: A0A1Z2XV78
names: Similarity
messages: Belongs to the serpin family.

1796620:ADH66 RS10350
gene id: 1796620:ADH66_RS10350
uniprot id: A0A1Z2XRE4
names: Subcellular Location Annotation
messages: Membrane

1796620:ADH66 RS16860
gene id: 1796620:ADH66_RS16860
uniprot id: A0A1Z2XUQ7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1796620:ADH66 RS15550
gene id: 1796620:ADH66_RS15550
uniprot id: A0A1Z2XU35
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1796620:ADH66 RS05130
gene id: 1796620:ADH66_RS05130
uniprot id: A0A1Z2XNS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796620:ADH66 RS05890
gene id: 1796620:ADH66_RS05890
uniprot id: A0A1Z2XP72
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1796620:ADH66 RS00790
gene id: 1796620:ADH66_RS00790
uniprot id: A0A1Z2XLJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1796620:ADH66 RS13450
gene id: 1796620:ADH66_RS13450
uniprot id: A0A1Z2XT14
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1796620:ADH66 RS13525
gene id: 1796620:ADH66_RS13525
uniprot id: A0A1Z2XT54
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.