1796616:A4V09 RS19420
gene id: 1796616:A4V09_RS19420
uniprot id: A0A1C7IDD7
names: Similarity
messages: Belongs to the CvfB family.

1796616:A4V09 RS05095
gene id: 1796616:A4V09_RS05095
uniprot id: A0A1C7I8K1
names: Similarity
messages: Belongs to the UPF0237 family.

1796616:A4V09 RS10200
gene id: 1796616:A4V09_RS10200
uniprot id: A0A1C7IB74
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796616:A4V09 RS03350
gene id: 1796616:A4V09_RS03350
uniprot id: A0A1C7IHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1796616:A4V09 RS02710
gene id: 1796616:A4V09_RS02710
uniprot id: A0A1C7IHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15790
gene id: 1796616:A4V09_RS15790
uniprot id: A0A1C7IFV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1796616:A4V09 RS11915
gene id: 1796616:A4V09_RS11915
uniprot id: A0A1C7I9M5
names: Similarity
messages: Belongs to the AOR/FOR family.

1796616:A4V09 RS04735
gene id: 1796616:A4V09_RS04735
uniprot id: A0A1C7I849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1796616:A4V09 RS14825
gene id: 1796616:A4V09_RS14825
uniprot id: A0A1C7IEJ5
names: Similarity
messages: Belongs to the EamA transporter family.

1796616:A4V09 RS03965
gene id: 1796616:A4V09_RS03965
uniprot id: A0A1C7I8W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1796616:A4V09 RS15995
gene id: 1796616:A4V09_RS15995
uniprot id: A0A1C7IDJ8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1796616:A4V09 RS17640
gene id: 1796616:A4V09_RS17640
uniprot id: A0A1C7IET3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS19505
gene id: 1796616:A4V09_RS19505
uniprot id: A0A1C7IDB8
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS15495
gene id: 1796616:A4V09_RS15495
uniprot id: A0A1C7IBH6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS15725
gene id: 1796616:A4V09_RS15725
uniprot id: A0A1C7IF06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1796616:A4V09 RS16225
gene id: 1796616:A4V09_RS16225
uniprot id: A0A1C7IBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS17380
gene id: 1796616:A4V09_RS17380
uniprot id: A0A1C7ICD8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1796616:A4V09 RS03985
gene id: 1796616:A4V09_RS03985
uniprot id: A0A1C7I818
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1796616:A4V09 RS22135
gene id: 1796616:A4V09_RS22135
uniprot id: A0A1C7IEP9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1796616:A4V09 RS24020
gene id: 1796616:A4V09_RS24020
uniprot id: A0A1C7IFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS18030
gene id: 1796616:A4V09_RS18030
uniprot id: A0A1C7IGZ1
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS05030
gene id: 1796616:A4V09_RS05030
uniprot id: A0A1C7IFW0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1796616:A4V09 RS03890
gene id: 1796616:A4V09_RS03890
uniprot id: A0A1C7I5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS23265
gene id: 1796616:A4V09_RS23265
uniprot id: A0A1C7IL13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1796616:A4V09 RS02255
gene id: 1796616:A4V09_RS02255
uniprot id: A0A1C7I4V3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS21275
gene id: 1796616:A4V09_RS21275
uniprot id: A0A1C7IIP7
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS21770
gene id: 1796616:A4V09_RS21770
uniprot id: A0A1C7IEH8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1796616:A4V09 RS00190
gene id: 1796616:A4V09_RS00190
uniprot id: A0A1C7IK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1796616:A4V09 RS18095
gene id: 1796616:A4V09_RS18095
uniprot id: A0A1C7IH01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1796616:A4V09 RS06475
gene id: 1796616:A4V09_RS06475
uniprot id: A0A1C7I6W0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1796616:A4V09 RS09915
gene id: 1796616:A4V09_RS09915
uniprot id: A0A1C7IBY4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS21585
gene id: 1796616:A4V09_RS21585
uniprot id: A0A1C7IEF4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1796616:A4V09 RS01475
gene id: 1796616:A4V09_RS01475
uniprot id: A0A1C7I4K8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS02680
gene id: 1796616:A4V09_RS02680
uniprot id: A0A1C7I5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1796616:A4V09 RS02715
gene id: 1796616:A4V09_RS02715
uniprot id: A0A1C7I527
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1796616:A4V09 RS08565
gene id: 1796616:A4V09_RS08565
uniprot id: A0A1C7IB97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1796616:A4V09 RS12295
gene id: 1796616:A4V09_RS12295
uniprot id: A0A1C7I9U8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1796616:A4V09 RS23055
gene id: 1796616:A4V09_RS23055
uniprot id: A0A1C7IFE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1796616:A4V09 RS20000
gene id: 1796616:A4V09_RS20000
uniprot id: A0A1C7IDP8
names: Similarity
messages: Belongs to the DapA family.

1796616:A4V09 RS11255
gene id: 1796616:A4V09_RS11255
uniprot id: A0A1C7IB60
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1796616:A4V09 RS10285
gene id: 1796616:A4V09_RS10285
uniprot id: A0A1C7I8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS04070
gene id: 1796616:A4V09_RS04070
uniprot id: A0A1C7I5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1796616:A4V09 RS07025
gene id: 1796616:A4V09_RS07025
uniprot id: A0A1C7I7B9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1796616:A4V09 RS19410
gene id: 1796616:A4V09_RS19410
uniprot id: A0A1C7IGV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1796616:A4V09 RS08275
gene id: 1796616:A4V09_RS08275
uniprot id: A0A1C7I7Y2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS06300
gene id: 1796616:A4V09_RS06300
uniprot id: A0A1C7I6Z0
names: Similarity
messages: Belongs to the EutP/PduV family.

1796616:A4V09 RS21620
gene id: 1796616:A4V09_RS21620
uniprot id: A0A1C7IGL7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS05690
gene id: 1796616:A4V09_RS05690
uniprot id: A0A1C7I8W3
names: Similarity
messages: Belongs to the CobH/CbiC family.

1796616:A4V09 RS02720
gene id: 1796616:A4V09_RS02720
uniprot id: A0A1C7IJF7
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS22355
gene id: 1796616:A4V09_RS22355
uniprot id: A0A1C7IGK5
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

1796616:A4V09 RS14795
gene id: 1796616:A4V09_RS14795
uniprot id: A0A1C7ID85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS17270
gene id: 1796616:A4V09_RS17270
uniprot id: A0A1C7IGC3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796616:A4V09 RS10815
gene id: 1796616:A4V09_RS10815
uniprot id: A0A1C7I999
names: Similarity
messages: Belongs to the RutC family.

1796616:A4V09 RS01975
gene id: 1796616:A4V09_RS01975
uniprot id: A0A1C7I4M4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1796616:A4V09 RS12020
gene id: 1796616:A4V09_RS12020
uniprot id: A0A1C7ID29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1796616:A4V09 RS17440
gene id: 1796616:A4V09_RS17440
uniprot id: A0A1C7ICE8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1796616:A4V09 RS09350
gene id: 1796616:A4V09_RS09350
uniprot id: A0A1C7ICJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS03805
gene id: 1796616:A4V09_RS03805
uniprot id: A0A1C7I5S0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1796616:A4V09 RS15485
gene id: 1796616:A4V09_RS15485
uniprot id: A0A1C7IEW1
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS17560
gene id: 1796616:A4V09_RS17560
uniprot id: A0A1C7ICG9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1796616:A4V09 RS10500
gene id: 1796616:A4V09_RS10500
uniprot id: A0A1C7ICA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1796616:A4V09 RS18685
gene id: 1796616:A4V09_RS18685
uniprot id: A0A1C7IHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1796616:A4V09 RS21460
gene id: 1796616:A4V09_RS21460
uniprot id: A0A1C7IEL9
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1796616:A4V09 RS11810
gene id: 1796616:A4V09_RS11810
uniprot id: A0A1C7I9K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1796616:A4V09 RS05500
gene id: 1796616:A4V09_RS05500
uniprot id: A0A1C7I6J8
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS10670
gene id: 1796616:A4V09_RS10670
uniprot id: A0A1C7I968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS21945
gene id: 1796616:A4V09_RS21945
uniprot id: A0A1C7IJ14
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS00030
gene id: 1796616:A4V09_RS00030
uniprot id: A0A1C7I5V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13550
gene id: 1796616:A4V09_RS13550
uniprot id: A0A1C7IAH3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1796616:A4V09 RS03485
gene id: 1796616:A4V09_RS03485
uniprot id: A0A1C7I5L3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS08290
gene id: 1796616:A4V09_RS08290
uniprot id: A0A1C7I7X6
names: Similarity
messages: Belongs to the type A lantibiotic family.

1796616:A4V09 RS16965
gene id: 1796616:A4V09_RS16965
uniprot id: A0A1C7IC72
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS10675
gene id: 1796616:A4V09_RS10675
uniprot id: A0A1C7IJR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12785
gene id: 1796616:A4V09_RS12785
uniprot id: A0A1C7IA49
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS07835
gene id: 1796616:A4V09_RS07835
uniprot id: A0A1C7I7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1796616:A4V09 RS08985
gene id: 1796616:A4V09_RS08985
uniprot id: A0A1C7I8C8
names: Similarity
messages: Belongs to the thioredoxin family.

1796616:A4V09 RS04550
gene id: 1796616:A4V09_RS04550
uniprot id: A0A1C7I8B1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1796616:A4V09 RS14175
gene id: 1796616:A4V09_RS14175
uniprot id: A0A1C7IB01
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1796616:A4V09 RS04075
gene id: 1796616:A4V09_RS04075
uniprot id: A0A1C7IKA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1796616:A4V09 RS19735
gene id: 1796616:A4V09_RS19735
uniprot id: A0A1C7IDI4
names: Similarity
messages: Belongs to the CpsD/CapB family.

1796616:A4V09 RS03475
gene id: 1796616:A4V09_RS03475
uniprot id: A0A1C7I7J2
names: Function
messages: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.

1796616:A4V09 RS00270
gene id: 1796616:A4V09_RS00270
uniprot id: A0A1C7I450
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1796616:A4V09 RS15800
gene id: 1796616:A4V09_RS15800
uniprot id: A0A1C7IDP6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1796616:A4V09 RS19495
gene id: 1796616:A4V09_RS19495
uniprot id: A0A1C7IDL9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796616:A4V09 RS12455
gene id: 1796616:A4V09_RS12455
uniprot id: A0A1C7IC20
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1796616:A4V09 RS14955
gene id: 1796616:A4V09_RS14955
uniprot id: A0A1C7IFF8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796616:A4V09 RS19150
gene id: 1796616:A4V09_RS19150
uniprot id: A0A1C7ID91
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1796616:A4V09 RS02355
gene id: 1796616:A4V09_RS02355
uniprot id: A0A1C7I4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1796616:A4V09 RS04805
gene id: 1796616:A4V09_RS04805
uniprot id: A0A1C7I607
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1796616:A4V09 RS20780
gene id: 1796616:A4V09_RS20780
uniprot id: A0A1C7IE04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS10505
gene id: 1796616:A4V09_RS10505
uniprot id: A0A1C7I8Z4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS14535
gene id: 1796616:A4V09_RS14535
uniprot id: A0A1C7IAY2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1796616:A4V09 RS08815
gene id: 1796616:A4V09_RS08815
uniprot id: A0A1C7IAA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15750
gene id: 1796616:A4V09_RS15750
uniprot id: A0A1C7IDN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1796616:A4V09 RS07950
gene id: 1796616:A4V09_RS07950
uniprot id: A0A1C7I9J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1796616:A4V09 RS02020
gene id: 1796616:A4V09_RS02020
uniprot id: A0A1C7I4Y4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS08530
gene id: 1796616:A4V09_RS08530
uniprot id: A0A1C7I848
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spermidine/spermine synthase family.
messages: Cell membrane

1796616:A4V09 RS04270
gene id: 1796616:A4V09_RS04270
uniprot id: A0A1C7I5S2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1796616:A4V09 RS17910
gene id: 1796616:A4V09_RS17910
uniprot id: A0A1C7IG33
names: Similarity
messages: Belongs to the EamA transporter family.

1796616:A4V09 RS06915
gene id: 1796616:A4V09_RS06915
uniprot id: A0A1C7I7A5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS20810
gene id: 1796616:A4V09_RS20810
uniprot id: A0A1C7IDY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1796616:A4V09 RS05170
gene id: 1796616:A4V09_RS05170
uniprot id: A0A1C7I660
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1796616:A4V09 RS15205
gene id: 1796616:A4V09_RS15205
uniprot id: A0A1C7ID60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1796616:A4V09 RS23760
gene id: 1796616:A4V09_RS23760
uniprot id: A0A1C7IFG0
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

1796616:A4V09 RS04140
gene id: 1796616:A4V09_RS04140
uniprot id: A0A1C7I9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1796616:A4V09 RS10600
gene id: 1796616:A4V09_RS10600
uniprot id: A0A1C7IAW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1796616:A4V09 RS14140
gene id: 1796616:A4V09_RS14140
uniprot id: A0A1C7ICM5
names: Similarity
messages: Belongs to the UxaA family.

1796616:A4V09 RS13840
gene id: 1796616:A4V09_RS13840
uniprot id: A0A1C7ICS2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1796616:A4V09 RS05405
gene id: 1796616:A4V09_RS05405
uniprot id: A0A1C7I9K4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1796616:A4V09 RS19740
gene id: 1796616:A4V09_RS19740
uniprot id: A0A1C7IFC1
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS12490
gene id: 1796616:A4V09_RS12490
uniprot id: A0A1C7I9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS21310
gene id: 1796616:A4V09_RS21310
uniprot id: A0A1C7IG30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1796616:A4V09 RS15840
gene id: 1796616:A4V09_RS15840
uniprot id: A0A1C7IFW6
names: Similarity
messages: Belongs to the peptidase M18 family.

1796616:A4V09 RS05770
gene id: 1796616:A4V09_RS05770
uniprot id: A0A1C7I6H0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1796616:A4V09 RS03285
gene id: 1796616:A4V09_RS03285
uniprot id: A0A1C7I5I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12255
gene id: 1796616:A4V09_RS12255
uniprot id: A0A1C7I9T7
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS09970
gene id: 1796616:A4V09_RS09970
uniprot id: A0A1C7IBZ4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1796616:A4V09 RS02215
gene id: 1796616:A4V09_RS02215
uniprot id: A0A1C7IHI3
names: Similarity
messages: Belongs to the GSP E family.

1796616:A4V09 RS19950
gene id: 1796616:A4V09_RS19950
uniprot id: A0A1C7IDN8
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1796616:A4V09 RS15360
gene id: 1796616:A4V09_RS15360
uniprot id: A0A1C7IBD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1796616:A4V09 RS21910
gene id: 1796616:A4V09_RS21910
uniprot id: A0A1C7IEH1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796616:A4V09 RS08970
gene id: 1796616:A4V09_RS08970
uniprot id: A0A1C7ICC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1796616:A4V09 RS02630
gene id: 1796616:A4V09_RS02630
uniprot id: A0A1C7I598
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1796616:A4V09 RS02785
gene id: 1796616:A4V09_RS02785
uniprot id: A0A1C7I7F5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1796616:A4V09 RS01985
gene id: 1796616:A4V09_RS01985
uniprot id: A0A1C7I7T5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1796616:A4V09 RS06710
gene id: 1796616:A4V09_RS06710
uniprot id: A0A1C7IAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1796616:A4V09 RS02295
gene id: 1796616:A4V09_RS02295
uniprot id: A0A1C7I4T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1796616:A4V09 RS05940
gene id: 1796616:A4V09_RS05940
uniprot id: A0A1C7I8I3
names: Similarity
messages: Belongs to the TrpC family.

1796616:A4V09 RS06840
gene id: 1796616:A4V09_RS06840
uniprot id: A0A1C7I9K5
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS12720
gene id: 1796616:A4V09_RS12720
uniprot id: A0A1C7IC74
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS07820
gene id: 1796616:A4V09_RS07820
uniprot id: A0A1C7I9S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1796616:A4V09 RS00415
gene id: 1796616:A4V09_RS00415
uniprot id: A0A1C7I721
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1796616:A4V09 RS20490
gene id: 1796616:A4V09_RS20490
uniprot id: A0A1C7IFP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1796616:A4V09 RS20590
gene id: 1796616:A4V09_RS20590
uniprot id: A0A1C7IIM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS07960
gene id: 1796616:A4V09_RS07960
uniprot id: A0A1C7I7Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1796616:A4V09 RS17295
gene id: 1796616:A4V09_RS17295
uniprot id: A0A1C7IEE6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS06995
gene id: 1796616:A4V09_RS06995
uniprot id: A0A1C7I7D3
names: Similarity
messages: Belongs to the UPF0758 family.

1796616:A4V09 RS15905
gene id: 1796616:A4V09_RS15905
uniprot id: A0A1C7IDZ1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1796616:A4V09 RS03220
gene id: 1796616:A4V09_RS03220
uniprot id: A0A1C7I779
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1796616:A4V09 RS11815
gene id: 1796616:A4V09_RS11815
uniprot id: A0A1C7IG47
names: Similarity
messages: Belongs to the peptidase C40 family.

1796616:A4V09 RS15460
gene id: 1796616:A4V09_RS15460
uniprot id: A0A1C7IDK0
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS10265
gene id: 1796616:A4V09_RS10265
uniprot id: A0A1C7I8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

1796616:A4V09 RS01385
gene id: 1796616:A4V09_RS01385
uniprot id: A0A1C7I4M7
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS04700
gene id: 1796616:A4V09_RS04700
uniprot id: A0A1C7I5Y7
names: Similarity
messages: Belongs to the UPF0246 family.

1796616:A4V09 RS03810
gene id: 1796616:A4V09_RS03810
uniprot id: A0A1C7I9P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1796616:A4V09 RS10660
gene id: 1796616:A4V09_RS10660
uniprot id: A0A1C7ICD2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS22340
gene id: 1796616:A4V09_RS22340
uniprot id: A0A1C7IF22
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS04750
gene id: 1796616:A4V09_RS04750
uniprot id: A0A1C7I5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1796616:A4V09 RS00400
gene id: 1796616:A4V09_RS00400
uniprot id: A0A1C7I3V6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

1796616:A4V09 RS11675
gene id: 1796616:A4V09_RS11675
uniprot id: A0A1C7I9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1796616:A4V09 RS05465
gene id: 1796616:A4V09_RS05465
uniprot id: A0A1C7I6G0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1796616:A4V09 RS21175
gene id: 1796616:A4V09_RS21175
uniprot id: A0A1C7IGE5
names: Similarity
messages: Belongs to the WXG100 family.

1796616:A4V09 RS21750
gene id: 1796616:A4V09_RS21750
uniprot id: A0A1C7IGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS03605
gene id: 1796616:A4V09_RS03605
uniprot id: A0A1C7I5N3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1796616:A4V09 RS13110
gene id: 1796616:A4V09_RS13110
uniprot id: A0A1C7IEH4
names: Similarity
messages: Belongs to the peptidase M20A family.

1796616:A4V09 RS20360
gene id: 1796616:A4V09_RS20360
uniprot id: A0A1C7IDR3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS11680
gene id: 1796616:A4V09_RS11680
uniprot id: A0A1C7I9L3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1796616:A4V09 RS18120
gene id: 1796616:A4V09_RS18120
uniprot id: A0A1C7ICP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1796616:A4V09 RS12200
gene id: 1796616:A4V09_RS12200
uniprot id: A0A1C7ID61
names: Similarity
messages: Belongs to the UPF0597 family.

1796616:A4V09 RS16375
gene id: 1796616:A4V09_RS16375
uniprot id: A0A1C7IBV3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1796616:A4V09 RS16865
gene id: 1796616:A4V09_RS16865
uniprot id: A0A1C7IC52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15820
gene id: 1796616:A4V09_RS15820
uniprot id: A0A1C7IDH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1796616:A4V09 RS06275
gene id: 1796616:A4V09_RS06275
uniprot id: A0A1C7IAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS04065
gene id: 1796616:A4V09_RS04065
uniprot id: A0A1C7I8Y0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1796616:A4V09 RS03570
gene id: 1796616:A4V09_RS03570
uniprot id: A0A1C7I8P5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1796616:A4V09 RS00520
gene id: 1796616:A4V09_RS00520
uniprot id: A0A1C7I742
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1796616:A4V09 RS17120
gene id: 1796616:A4V09_RS17120
uniprot id: A0A1C7IC67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS12805
gene id: 1796616:A4V09_RS12805
uniprot id: A0A1C7IA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1796616:A4V09 RS16950
gene id: 1796616:A4V09_RS16950
uniprot id: A0A1C7IE96
names: Similarity
messages: Belongs to the HdrA family.

1796616:A4V09 RS16130
gene id: 1796616:A4V09_RS16130
uniprot id: A0A1C7IE34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1796616:A4V09 RS14005
gene id: 1796616:A4V09_RS14005
uniprot id: A0A1C7IEY8
names: Similarity
messages: Belongs to the hyi family.

1796616:A4V09 RS23630
gene id: 1796616:A4V09_RS23630
uniprot id: A0A1C7IFG2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1796616:A4V09 RS22555
gene id: 1796616:A4V09_RS22555
uniprot id: A0A1C7IEZ5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1796616:A4V09 RS11745
gene id: 1796616:A4V09_RS11745
uniprot id: A0A1C7IBF3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS19840
gene id: 1796616:A4V09_RS19840
uniprot id: A0A1C7IDL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS17915
gene id: 1796616:A4V09_RS17915
uniprot id: A0A1C7ICJ8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1796616:A4V09 RS00450
gene id: 1796616:A4V09_RS00450
uniprot id: A0A1C7I439
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12190
gene id: 1796616:A4V09_RS12190
uniprot id: A0A1C7I9V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS16100
gene id: 1796616:A4V09_RS16100
uniprot id: A0A1C7IBS1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1796616:A4V09 RS04215
gene id: 1796616:A4V09_RS04215
uniprot id: A0A1C7I5Z5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS17095
gene id: 1796616:A4V09_RS17095
uniprot id: A0A1C7IC97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1796616:A4V09 RS21600
gene id: 1796616:A4V09_RS21600
uniprot id: A0A1C7IEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

1796616:A4V09 RS22275
gene id: 1796616:A4V09_RS22275
uniprot id: A0A1C7IJ76
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1796616:A4V09 RS21170
gene id: 1796616:A4V09_RS21170
uniprot id: A0A1C7IGI7
names: Similarity
messages: Belongs to the WXG100 family.

1796616:A4V09 RS12710
gene id: 1796616:A4V09_RS12710
uniprot id: A0A1C7IE98
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796616:A4V09 RS03235
gene id: 1796616:A4V09_RS03235
uniprot id: A0A1C7I5H4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1796616:A4V09 RS22895
gene id: 1796616:A4V09_RS22895
uniprot id: A0A1C7IFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

1796616:A4V09 RS09145
gene id: 1796616:A4V09_RS09145
uniprot id: A0A1C7IBK2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1796616:A4V09 RS15685
gene id: 1796616:A4V09_RS15685
uniprot id: A0A1C7IFT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1796616:A4V09 RS06985
gene id: 1796616:A4V09_RS06985
uniprot id: A0A1C7IG58
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1796616:A4V09 RS17940
gene id: 1796616:A4V09_RS17940
uniprot id: A0A1C7IEQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS16915
gene id: 1796616:A4V09_RS16915
uniprot id: A0A1C7IDZ3
names: Similarity
messages: Belongs to the class-I fumarase family.

1796616:A4V09 RS17105
gene id: 1796616:A4V09_RS17105
uniprot id: A0A1C7IEJ3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1796616:A4V09 RS16550
gene id: 1796616:A4V09_RS16550
uniprot id: A0A1C7IBX8
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS16435
gene id: 1796616:A4V09_RS16435
uniprot id: A0A1C7IBW3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS17205
gene id: 1796616:A4V09_RS17205
uniprot id: A0A1C7IE33
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1796616:A4V09 RS20460
gene id: 1796616:A4V09_RS20460
uniprot id: A0A1C7IG63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS15560
gene id: 1796616:A4V09_RS15560
uniprot id: A0A1C7IBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1796616:A4V09 RS03955
gene id: 1796616:A4V09_RS03955
uniprot id: A0A1C7IFW4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS16425
gene id: 1796616:A4V09_RS16425
uniprot id: A0A1C7IE09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1796616:A4V09 RS10190
gene id: 1796616:A4V09_RS10190
uniprot id: A0A1C7I8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS14910
gene id: 1796616:A4V09_RS14910
uniprot id: A0A1C7IBC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1796616:A4V09 RS07410
gene id: 1796616:A4V09_RS07410
uniprot id: A0A1C7I9A3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1796616:A4V09 RS05265
gene id: 1796616:A4V09_RS05265
uniprot id: A0A1C7I8E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1796616:A4V09 RS16040
gene id: 1796616:A4V09_RS16040
uniprot id: A0A1C7IBQ9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS03845
gene id: 1796616:A4V09_RS03845
uniprot id: A0A1C7I8U4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1796616:A4V09 RS01765
gene id: 1796616:A4V09_RS01765
uniprot id: A0A1C7I6X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS21825
gene id: 1796616:A4V09_RS21825
uniprot id: A0A1C7IEL1
names: Similarity
messages: Belongs to the GSP E family.

1796616:A4V09 RS11235
gene id: 1796616:A4V09_RS11235
uniprot id: A0A1C7IBF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1796616:A4V09 RS02490
gene id: 1796616:A4V09_RS02490
uniprot id: A0A1C7I547
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS02285
gene id: 1796616:A4V09_RS02285
uniprot id: A0A1C7I533
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

1796616:A4V09 RS10965
gene id: 1796616:A4V09_RS10965
uniprot id: A0A1C7I974
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS12185
gene id: 1796616:A4V09_RS12185
uniprot id: A0A1C7I9S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13495
gene id: 1796616:A4V09_RS13495
uniprot id: A0A1C7IAG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1796616:A4V09 RS05710
gene id: 1796616:A4V09_RS05710
uniprot id: A0A1C7I6G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1796616:A4V09 RS24035
gene id: 1796616:A4V09_RS24035
uniprot id: A0A1C7IHV4
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1796616:A4V09 RS19930
gene id: 1796616:A4V09_RS19930
uniprot id: A0A1C7IFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1796616:A4V09 RS09430
gene id: 1796616:A4V09_RS09430
uniprot id: A0A1C7IAB3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS13240
gene id: 1796616:A4V09_RS13240
uniprot id: A0A1C7ICG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1796616:A4V09 RS10810
gene id: 1796616:A4V09_RS10810
uniprot id: A0A1C7IB79
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1796616:A4V09 RS16415
gene id: 1796616:A4V09_RS16415
uniprot id: A0A1C7IE86
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS06015
gene id: 1796616:A4V09_RS06015
uniprot id: A0A1C7I929
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS16930
gene id: 1796616:A4V09_RS16930
uniprot id: A0A1C7IC45
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1796616:A4V09 RS21555
gene id: 1796616:A4V09_RS21555
uniprot id: A0A1C7IEG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS10275
gene id: 1796616:A4V09_RS10275
uniprot id: A0A1C7IAQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS03555
gene id: 1796616:A4V09_RS03555
uniprot id: A0A1C7I5M0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1796616:A4V09 RS02135
gene id: 1796616:A4V09_RS02135
uniprot id: A0A1C7I6M3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1796616:A4V09 RS00940
gene id: 1796616:A4V09_RS00940
uniprot id: A0A1C7I4D4
names: Similarity
messages: Belongs to the IMPACT family.

1796616:A4V09 RS00220
gene id: 1796616:A4V09_RS00220
uniprot id: A0A1C7I3S5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1796616:A4V09 RS22370
gene id: 1796616:A4V09_RS22370
uniprot id: A0A1C7IEW2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1796616:A4V09 RS13565
gene id: 1796616:A4V09_RS13565
uniprot id: A0A1C7IDV7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1796616:A4V09 RS12730
gene id: 1796616:A4V09_RS12730
uniprot id: A0A1C7IA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS22950
gene id: 1796616:A4V09_RS22950
uniprot id: A0A1C7IF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20945
gene id: 1796616:A4V09_RS20945
uniprot id: A0A1C7III6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS08015
gene id: 1796616:A4V09_RS08015
uniprot id: A0A1C7I7S1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS06910
gene id: 1796616:A4V09_RS06910
uniprot id: A0A1C7I7C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1796616:A4V09 RS02065
gene id: 1796616:A4V09_RS02065
uniprot id: A0A1C7I6T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1796616:A4V09 RS23135
gene id: 1796616:A4V09_RS23135
uniprot id: A0A1C7IIX2
names: Similarity
messages: Belongs to the FGGY kinase family.

1796616:A4V09 RS09175
gene id: 1796616:A4V09_RS09175
uniprot id: A0A1C7IAF6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS18070
gene id: 1796616:A4V09_RS18070
uniprot id: A0A1C7IEI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1796616:A4V09 RS15200
gene id: 1796616:A4V09_RS15200
uniprot id: A0A1C7IBB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1796616:A4V09 RS14855
gene id: 1796616:A4V09_RS14855
uniprot id: A0A1C7IBB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

1796616:A4V09 RS05130
gene id: 1796616:A4V09_RS05130
uniprot id: A0A1C7I9G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1796616:A4V09 RS12100
gene id: 1796616:A4V09_RS12100
uniprot id: A0A1C7IDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS10235
gene id: 1796616:A4V09_RS10235
uniprot id: A0A1C7I8U7
names: Function
names: Subunit
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1796616:A4V09 RS06595
gene id: 1796616:A4V09_RS06595
uniprot id: A0A1C7I6Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1796616:A4V09 RS02660
gene id: 1796616:A4V09_RS02660
uniprot id: A0A1C7I576
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1796616:A4V09 RS15180
gene id: 1796616:A4V09_RS15180
uniprot id: A0A1C7IDM2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1796616:A4V09 RS13965
gene id: 1796616:A4V09_RS13965
uniprot id: A0A1C7IAW2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1796616:A4V09 RS23920
gene id: 1796616:A4V09_RS23920
uniprot id: A0A1C7IGI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1796616:A4V09 RS11215
gene id: 1796616:A4V09_RS11215
uniprot id: A0A1C7I9B0
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS03370
gene id: 1796616:A4V09_RS03370
uniprot id: A0A1C7IJG8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1796616:A4V09 RS00145
gene id: 1796616:A4V09_RS00145
uniprot id: A0A1C7I7W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1796616:A4V09 RS21730
gene id: 1796616:A4V09_RS21730
uniprot id: A0A1C7IGS8
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS05440
gene id: 1796616:A4V09_RS05440
uniprot id: A0A1C7I6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1796616:A4V09 RS19925
gene id: 1796616:A4V09_RS19925
uniprot id: A0A1C7IDL0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS19270
gene id: 1796616:A4V09_RS19270
uniprot id: A0A1C7IFF3
names: Similarity
messages: Belongs to the peptidase C40 family.

1796616:A4V09 RS10075
gene id: 1796616:A4V09_RS10075
uniprot id: A0A1C7IC15
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

1796616:A4V09 RS02990
gene id: 1796616:A4V09_RS02990
uniprot id: A0A1C7I730
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS04010
gene id: 1796616:A4V09_RS04010
uniprot id: A0A1C7I7L2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1796616:A4V09 RS23520
gene id: 1796616:A4V09_RS23520
uniprot id: A0A1C7IFM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS06215
gene id: 1796616:A4V09_RS06215
uniprot id: A0A1C7I6Z4
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1796616:A4V09 RS23405
gene id: 1796616:A4V09_RS23405
uniprot id: A0A1C7IHG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

1796616:A4V09 RS11840
gene id: 1796616:A4V09_RS11840
uniprot id: A0A1C7I9T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1796616:A4V09 RS13235
gene id: 1796616:A4V09_RS13235
uniprot id: A0A1C7IKM2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1796616:A4V09 RS16045
gene id: 1796616:A4V09_RS16045
uniprot id: A0A1C7II19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS06570
gene id: 1796616:A4V09_RS06570
uniprot id: A0A1C7IB22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1796616:A4V09 RS03240
gene id: 1796616:A4V09_RS03240
uniprot id: A0A1C7I9F7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1796616:A4V09 RS07015
gene id: 1796616:A4V09_RS07015
uniprot id: A0A1C7IFT5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796616:A4V09 RS05895
gene id: 1796616:A4V09_RS05895
uniprot id: A0A1C7I6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS08700
gene id: 1796616:A4V09_RS08700
uniprot id: A0A1C7IAH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS23355
gene id: 1796616:A4V09_RS23355
uniprot id: A0A1C7IHG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1796616:A4V09 RS11515
gene id: 1796616:A4V09_RS11515
uniprot id: A0A1C7I9H3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1796616:A4V09 RS11350
gene id: 1796616:A4V09_RS11350
uniprot id: A0A1C7I9E2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1796616:A4V09 RS08555
gene id: 1796616:A4V09_RS08555
uniprot id: A0A1C7I9V8
names: Similarity
messages: Belongs to the threonine synthase family.

1796616:A4V09 RS07655
gene id: 1796616:A4V09_RS07655
uniprot id: A0A1C7I7Q4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1796616:A4V09 RS15525
gene id: 1796616:A4V09_RS15525
uniprot id: A0A1C7IDK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm

1796616:A4V09 RS07875
gene id: 1796616:A4V09_RS07875
uniprot id: A0A1C7I9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1796616:A4V09 RS15650
gene id: 1796616:A4V09_RS15650
uniprot id: A0A1C7IBR6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796616:A4V09 RS08220
gene id: 1796616:A4V09_RS08220
uniprot id: A0A1C7I7X2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS02175
gene id: 1796616:A4V09_RS02175
uniprot id: A0A1C7I513
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1796616:A4V09 RS04375
gene id: 1796616:A4V09_RS04375
uniprot id: A0A1C7IG25
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS14670
gene id: 1796616:A4V09_RS14670
uniprot id: A0A1C7ID67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1796616:A4V09 RS05420
gene id: 1796616:A4V09_RS05420
uniprot id: A0A1C7IAG4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1796616:A4V09 RS12505
gene id: 1796616:A4V09_RS12505
uniprot id: A0A1C7ICB4
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS22830
gene id: 1796616:A4V09_RS22830
uniprot id: A0A1C7IJH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS10225
gene id: 1796616:A4V09_RS10225
uniprot id: A0A1C7IAP3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS16220
gene id: 1796616:A4V09_RS16220
uniprot id: A0A1C7IBS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS22265
gene id: 1796616:A4V09_RS22265
uniprot id: A0A1C7IER1
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1796616:A4V09 RS10260
gene id: 1796616:A4V09_RS10260
uniprot id: A0A1C7I900
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1796616:A4V09 RS04725
gene id: 1796616:A4V09_RS04725
uniprot id: A0A1C7IA45
names: Similarity
messages: Belongs to the CarB family.

1796616:A4V09 RS02685
gene id: 1796616:A4V09_RS02685
uniprot id: A0A1C7I572
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1796616:A4V09 RS18845
gene id: 1796616:A4V09_RS18845
uniprot id: A0A1C7ID43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1796616:A4V09 RS07975
gene id: 1796616:A4V09_RS07975
uniprot id: A0A1C7IBT8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1796616:A4V09 RS11825
gene id: 1796616:A4V09_RS11825
uniprot id: A0A1C7IDT6
names: Similarity
messages: Belongs to the ribF family.

1796616:A4V09 RS06950
gene id: 1796616:A4V09_RS06950
uniprot id: A0A1C7I9M1
names: Similarity
messages: Belongs to the peptidase S11 family.

1796616:A4V09 RS06020
gene id: 1796616:A4V09_RS06020
uniprot id: A0A1C7I8U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796616:A4V09 RS22235
gene id: 1796616:A4V09_RS22235
uniprot id: A0A1C7IGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1796616:A4V09 RS13535
gene id: 1796616:A4V09_RS13535
uniprot id: A0A1C7ICU8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1796616:A4V09 RS16320
gene id: 1796616:A4V09_RS16320
uniprot id: A0A1C7IBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1796616:A4V09 RS12365
gene id: 1796616:A4V09_RS12365
uniprot id: A0A1C7ID88
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS15890
gene id: 1796616:A4V09_RS15890
uniprot id: A0A1C7IBL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1796616:A4V09 RS15635
gene id: 1796616:A4V09_RS15635
uniprot id: A0A1C7IKR5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1796616:A4V09 RS22290
gene id: 1796616:A4V09_RS22290
uniprot id: A0A1C7IF11
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS18165
gene id: 1796616:A4V09_RS18165
uniprot id: A0A1C7IEU9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1796616:A4V09 RS14980
gene id: 1796616:A4V09_RS14980
uniprot id: A0A1C7IB59
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1796616:A4V09 RS04130
gene id: 1796616:A4V09_RS04130
uniprot id: A0A1C7I5T1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS04760
gene id: 1796616:A4V09_RS04760
uniprot id: A0A1C7I9A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1796616:A4V09 RS12525
gene id: 1796616:A4V09_RS12525
uniprot id: A0A1C7IA04
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1796616:A4V09 RS23400
gene id: 1796616:A4V09_RS23400
uniprot id: A0A1C7IHK2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1796616:A4V09 RS04535
gene id: 1796616:A4V09_RS04535
uniprot id: A0A1C7I603
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1796616:A4V09 RS21815
gene id: 1796616:A4V09_RS21815
uniprot id: A0A1C7II61
names: Similarity
messages: Belongs to the peptidase A24 family.

1796616:A4V09 RS10030
gene id: 1796616:A4V09_RS10030
uniprot id: A0A1C7I8Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1796616:A4V09 RS14070
gene id: 1796616:A4V09_RS14070
uniprot id: A0A1C7ICV9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1796616:A4V09 RS23420
gene id: 1796616:A4V09_RS23420
uniprot id: A0A1C7IFD5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1796616:A4V09 RS22735
gene id: 1796616:A4V09_RS22735
uniprot id: A0A1C7IHA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12660
gene id: 1796616:A4V09_RS12660
uniprot id: A0A1C7ICE3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796616:A4V09 RS04955
gene id: 1796616:A4V09_RS04955
uniprot id: A0A1C7I6C5
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1796616:A4V09 RS08945
gene id: 1796616:A4V09_RS08945
uniprot id: A0A1C7I882
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1796616:A4V09 RS13660
gene id: 1796616:A4V09_RS13660
uniprot id: A0A1C7ICX3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1796616:A4V09 RS02165
gene id: 1796616:A4V09_RS02165
uniprot id: A0A1C7I746
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1796616:A4V09 RS01345
gene id: 1796616:A4V09_RS01345
uniprot id: A0A1C7I7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12830
gene id: 1796616:A4V09_RS12830
uniprot id: A0A1C7IC94
names: Similarity
messages: Belongs to the UPF0751 family.

1796616:A4V09 RS11880
gene id: 1796616:A4V09_RS11880
uniprot id: A0A1C7IC07
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1796616:A4V09 RS17565
gene id: 1796616:A4V09_RS17565
uniprot id: A0A1C7IE93
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1796616:A4V09 RS13575
gene id: 1796616:A4V09_RS13575
uniprot id: A0A1C7IG23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1796616:A4V09 RS03185
gene id: 1796616:A4V09_RS03185
uniprot id: A0A1C7I9E7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1796616:A4V09 RS16300
gene id: 1796616:A4V09_RS16300
uniprot id: A0A1C7IE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20295
gene id: 1796616:A4V09_RS20295
uniprot id: A0A1C7IFY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15745
gene id: 1796616:A4V09_RS15745
uniprot id: A0A1C7IDW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1796616:A4V09 RS12680
gene id: 1796616:A4V09_RS12680
uniprot id: A0A1C7IA33
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1796616:A4V09 RS21435
gene id: 1796616:A4V09_RS21435
uniprot id: A0A1C7IEB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS03465
gene id: 1796616:A4V09_RS03465
uniprot id: A0A1C7I9J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1796616:A4V09 RS04545
gene id: 1796616:A4V09_RS04545
uniprot id: A0A1C7IA15
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1796616:A4V09 RS12035
gene id: 1796616:A4V09_RS12035
uniprot id: A0A1C7IDX6
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS08995
gene id: 1796616:A4V09_RS08995
uniprot id: A0A1C7I890
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS07900
gene id: 1796616:A4V09_RS07900
uniprot id: A0A1C7IAX8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1796616:A4V09 RS19400
gene id: 1796616:A4V09_RS19400
uniprot id: A0A1C7IDD2
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS00905
gene id: 1796616:A4V09_RS00905
uniprot id: A0A1C7I4F9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1796616:A4V09 RS04440
gene id: 1796616:A4V09_RS04440
uniprot id: A0A1C7I664
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1796616:A4V09 RS13245
gene id: 1796616:A4V09_RS13245
uniprot id: A0A1C7IAJ8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1796616:A4V09 RS04435
gene id: 1796616:A4V09_RS04435
uniprot id: A0A1C7I804
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796616:A4V09 RS05715
gene id: 1796616:A4V09_RS05715
uniprot id: A0A1C7I8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1796616:A4V09 RS23890
gene id: 1796616:A4V09_RS23890
uniprot id: A0A1C7IKA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1796616:A4V09 RS14675
gene id: 1796616:A4V09_RS14675
uniprot id: A0A1C7IB94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1796616:A4V09 RS15210
gene id: 1796616:A4V09_RS15210
uniprot id: A0A1C7IER7
names: Similarity
messages: Belongs to the DprA/Smf family.

1796616:A4V09 RS12770
gene id: 1796616:A4V09_RS12770
uniprot id: A0A1C7IC85
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1796616:A4V09 RS03245
gene id: 1796616:A4V09_RS03245
uniprot id: A0A1C7I7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS07615
gene id: 1796616:A4V09_RS07615
uniprot id: A0A1C7I9D1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS21075
gene id: 1796616:A4V09_RS21075
uniprot id: A0A1C7IE61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1796616:A4V09 RS23425
gene id: 1796616:A4V09_RS23425
uniprot id: A0A1C7IH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1796616:A4V09 RS08650
gene id: 1796616:A4V09_RS08650
uniprot id: A0A1C7IA62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1796616:A4V09 RS00405
gene id: 1796616:A4V09_RS00405
uniprot id: A0A1C7I5T5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1796616:A4V09 RS04015
gene id: 1796616:A4V09_RS04015
uniprot id: A0A1C7I8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13015
gene id: 1796616:A4V09_RS13015
uniprot id: A0A1C7IC40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS00355
gene id: 1796616:A4V09_RS00355
uniprot id: A0A1C7IHS8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS03575
gene id: 1796616:A4V09_RS03575
uniprot id: A0A1C7I5I6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1796616:A4V09 RS08110
gene id: 1796616:A4V09_RS08110
uniprot id: A0A1C7I9P0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS00505
gene id: 1796616:A4V09_RS00505
uniprot id: A0A1C7I447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1796616:A4V09 RS17580
gene id: 1796616:A4V09_RS17580
uniprot id: A0A1C7ICH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1796616:A4V09 RS13155
gene id: 1796616:A4V09_RS13155
uniprot id: A0A1C7IDN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS10485
gene id: 1796616:A4V09_RS10485
uniprot id: A0A1C7I8Z1
names: Subcellular Location Annotation
messages: Cytoplasm

1796616:A4V09 RS03495
gene id: 1796616:A4V09_RS03495
uniprot id: A0A1C7II14
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1796616:A4V09 RS20530
gene id: 1796616:A4V09_RS20530
uniprot id: A0A1C7IKY2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1796616:A4V09 RS11650
gene id: 1796616:A4V09_RS11650
uniprot id: A0A1C7I9M8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS05655
gene id: 1796616:A4V09_RS05655
uniprot id: A0A1C7I6M5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1796616:A4V09 RS00160
gene id: 1796616:A4V09_RS00160
uniprot id: A0A1C7I431
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796616:A4V09 RS10145
gene id: 1796616:A4V09_RS10145
uniprot id: A0A1C7ICX7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1796616:A4V09 RS08950
gene id: 1796616:A4V09_RS08950
uniprot id: A0A1C7IA40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1796616:A4V09 RS16245
gene id: 1796616:A4V09_RS16245
uniprot id: A0A1C7IDX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS20445
gene id: 1796616:A4V09_RS20445
uniprot id: A0A1C7IDU8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796616:A4V09 RS19820
gene id: 1796616:A4V09_RS19820
uniprot id: A0A1C7IIL5
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1796616:A4V09 RS15675
gene id: 1796616:A4V09_RS15675
uniprot id: A0A1C7IBH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1796616:A4V09 RS01770
gene id: 1796616:A4V09_RS01770
uniprot id: A0A1C7I6N6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS22785
gene id: 1796616:A4V09_RS22785
uniprot id: A0A1C7IHB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS03635
gene id: 1796616:A4V09_RS03635
uniprot id: A0A1C7I5Q0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS04145
gene id: 1796616:A4V09_RS04145
uniprot id: A0A1C7I845
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS07860
gene id: 1796616:A4V09_RS07860
uniprot id: A0A1C7I7S8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1796616:A4V09 RS11800
gene id: 1796616:A4V09_RS11800
uniprot id: A0A1C7IG02
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1796616:A4V09 RS21790
gene id: 1796616:A4V09_RS21790
uniprot id: A0A1C7IGQ0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1796616:A4V09 RS20815
gene id: 1796616:A4V09_RS20815
uniprot id: A0A1C7IE13
names: Similarity
messages: Belongs to the CapA family.

1796616:A4V09 RS06340
gene id: 1796616:A4V09_RS06340
uniprot id: A0A1C7I906
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1796616:A4V09 RS10440
gene id: 1796616:A4V09_RS10440
uniprot id: A0A1C7I8Y2
names: Similarity
messages: Belongs to the class-I fumarase family.

1796616:A4V09 RS20285
gene id: 1796616:A4V09_RS20285
uniprot id: A0A1C7II54
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1796616:A4V09 RS04910
gene id: 1796616:A4V09_RS04910
uniprot id: A0A1C7I6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1796616:A4V09 RS15290
gene id: 1796616:A4V09_RS15290
uniprot id: A0A1C7IDG9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1796616:A4V09 RS05650
gene id: 1796616:A4V09_RS05650
uniprot id: A0A1C7II47
names: Similarity
messages: Belongs to the CobT family.

1796616:A4V09 RS14750
gene id: 1796616:A4V09_RS14750
uniprot id: A0A1C7IB36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15300
gene id: 1796616:A4V09_RS15300
uniprot id: A0A1C7IBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1796616:A4V09 RS16410
gene id: 1796616:A4V09_RS16410
uniprot id: A0A1C7IG65
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1796616:A4V09 RS15690
gene id: 1796616:A4V09_RS15690
uniprot id: A0A1C7IDV1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1796616:A4V09 RS04110
gene id: 1796616:A4V09_RS04110
uniprot id: A0A1C7I5P1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS18160
gene id: 1796616:A4V09_RS18160
uniprot id: A0A1C7IF24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1796616:A4V09 RS00980
gene id: 1796616:A4V09_RS00980
uniprot id: A0A1C7I632
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1796616:A4V09 RS23305
gene id: 1796616:A4V09_RS23305
uniprot id: A0A1C7IFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS14930
gene id: 1796616:A4V09_RS14930
uniprot id: A0A1C7IEL5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1796616:A4V09 RS08285
gene id: 1796616:A4V09_RS08285
uniprot id: A0A1C7I7X6
names: Similarity
messages: Belongs to the type A lantibiotic family.

1796616:A4V09 RS12425
gene id: 1796616:A4V09_RS12425
uniprot id: A0A1C7IDA1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796616:A4V09 RS11580
gene id: 1796616:A4V09_RS11580
uniprot id: A0A1C7IIC3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS02320
gene id: 1796616:A4V09_RS02320
uniprot id: A0A1C7I517
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1796616:A4V09 RS11275
gene id: 1796616:A4V09_RS11275
uniprot id: A0A1C7IDJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1796616:A4V09 RS10165
gene id: 1796616:A4V09_RS10165
uniprot id: A0A1C7I8T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1796616:A4V09 RS07995
gene id: 1796616:A4V09_RS07995
uniprot id: A0A1C7I7T2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS06565
gene id: 1796616:A4V09_RS06565
uniprot id: A0A1C7I750
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1796616:A4V09 RS22730
gene id: 1796616:A4V09_RS22730
uniprot id: A0A1C7IJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS08695
gene id: 1796616:A4V09_RS08695
uniprot id: A0A1C7IC63
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1796616:A4V09 RS15040
gene id: 1796616:A4V09_RS15040
uniprot id: A0A1C7ID33
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS23935
gene id: 1796616:A4V09_RS23935
uniprot id: A0A1C7IHB8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1796616:A4V09 RS06150
gene id: 1796616:A4V09_RS06150
uniprot id: A0A1C7I8L7
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1796616:A4V09 RS22410
gene id: 1796616:A4V09_RS22410
uniprot id: A0A1C7IGL4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796616:A4V09 RS04290
gene id: 1796616:A4V09_RS04290
uniprot id: A0A1C7I619
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1796616:A4V09 RS12460
gene id: 1796616:A4V09_RS12460
uniprot id: A0A1C7IA50
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1796616:A4V09 RS07940
gene id: 1796616:A4V09_RS07940
uniprot id: A0A1C7I7S3
names: Similarity
messages: Belongs to the CinA family.

1796616:A4V09 RS18895
gene id: 1796616:A4V09_RS18895
uniprot id: A0A1C7IDB1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1796616:A4V09 RS22965
gene id: 1796616:A4V09_RS22965
uniprot id: A0A1C7IIT9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS11705
gene id: 1796616:A4V09_RS11705
uniprot id: A0A1C7IDR8
names: Similarity
messages: Belongs to the UxaA family.

1796616:A4V09 RS03945
gene id: 1796616:A4V09_RS03945
uniprot id: A0A1C7I5U1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796616:A4V09 RS15780
gene id: 1796616:A4V09_RS15780
uniprot id: A0A1C7IBK0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1796616:A4V09 RS21885
gene id: 1796616:A4V09_RS21885
uniprot id: A0A1C7IEM1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796616:A4V09 RS01275
gene id: 1796616:A4V09_RS01275
uniprot id: A0A1C7I4B9
names: Similarity
messages: Belongs to the EamA transporter family.

1796616:A4V09 RS01375
gene id: 1796616:A4V09_RS01375
uniprot id: A0A1C7IFJ6
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS10460
gene id: 1796616:A4V09_RS10460
uniprot id: A0A1C7I928
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS06200
gene id: 1796616:A4V09_RS06200
uniprot id: A0A1C7I8M8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1796616:A4V09 RS09250
gene id: 1796616:A4V09_RS09250
uniprot id: A0A1C7I8G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1796616:A4V09 RS05620
gene id: 1796616:A4V09_RS05620
uniprot id: A0A1C7I6J2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1796616:A4V09 RS17420
gene id: 1796616:A4V09_RS17420
uniprot id: A0A1C7IEP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1796616:A4V09 RS22795
gene id: 1796616:A4V09_RS22795
uniprot id: A0A1C7IFA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS14965
gene id: 1796616:A4V09_RS14965
uniprot id: A0A1C7IDB4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1796616:A4V09 RS08635
gene id: 1796616:A4V09_RS08635
uniprot id: A0A1C7I862
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1796616:A4V09 RS16265
gene id: 1796616:A4V09_RS16265
uniprot id: A0A1C7IBT7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1796616:A4V09 RS01995
gene id: 1796616:A4V09_RS01995
uniprot id: A0A1C7IFQ6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1796616:A4V09 RS22200
gene id: 1796616:A4V09_RS22200
uniprot id: A0A1C7IGI0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS04000
gene id: 1796616:A4V09_RS04000
uniprot id: A0A1C7I5V5
names: Cofactor
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1796616:A4V09 RS05720
gene id: 1796616:A4V09_RS05720
uniprot id: A0A1C7II13
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1796616:A4V09 RS06240
gene id: 1796616:A4V09_RS06240
uniprot id: A0A1C7I6Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1796616:A4V09 RS23285
gene id: 1796616:A4V09_RS23285
uniprot id: A0A1C7IHG2
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1796616:A4V09 RS00210
gene id: 1796616:A4V09_RS00210
uniprot id: A0A1C7I440
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS19580
gene id: 1796616:A4V09_RS19580
uniprot id: A0A1C7IDE0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1796616:A4V09 RS03980
gene id: 1796616:A4V09_RS03980
uniprot id: A0A1C7I9S2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1796616:A4V09 RS10300
gene id: 1796616:A4V09_RS10300
uniprot id: A0A1C7IIA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS16545
gene id: 1796616:A4V09_RS16545
uniprot id: A0A1C7IC77
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS16345
gene id: 1796616:A4V09_RS16345
uniprot id: A0A1C7IBY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS04990
gene id: 1796616:A4V09_RS04990
uniprot id: A0A1C7I6F7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1796616:A4V09 RS15015
gene id: 1796616:A4V09_RS15015
uniprot id: A0A1C7IDJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS06000
gene id: 1796616:A4V09_RS06000
uniprot id: A0A1C7I6R2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1796616:A4V09 RS05070
gene id: 1796616:A4V09_RS05070
uniprot id: A0A1C7I9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1796616:A4V09 RS16215
gene id: 1796616:A4V09_RS16215
uniprot id: A0A1C7IFA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1796616:A4V09 RS01035
gene id: 1796616:A4V09_RS01035
uniprot id: A0A1C7I4E2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS19055
gene id: 1796616:A4V09_RS19055
uniprot id: A0A1C7ID54
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS17140
gene id: 1796616:A4V09_RS17140
uniprot id: A0A1C7IFQ1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1796616:A4V09 RS17555
gene id: 1796616:A4V09_RS17555
uniprot id: A0A1C7ICD1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1796616:A4V09 RS06155
gene id: 1796616:A4V09_RS06155
uniprot id: A0A1C7IA19
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS02170
gene id: 1796616:A4V09_RS02170
uniprot id: A0A1C7I6V7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS24045
gene id: 1796616:A4V09_RS24045
uniprot id: A0A1C7IFV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1796616:A4V09 RS10890
gene id: 1796616:A4V09_RS10890
uniprot id: A0A1C7IGB4
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1796616:A4V09 RS14960
gene id: 1796616:A4V09_RS14960
uniprot id: A0A1C7IDI7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

1796616:A4V09 RS19500
gene id: 1796616:A4V09_RS19500
uniprot id: A0A1C7IIK7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1796616:A4V09 RS01990
gene id: 1796616:A4V09_RS01990
uniprot id: A0A1C7I4P8
names: Similarity
messages: Belongs to the urocanase family.

1796616:A4V09 RS03825
gene id: 1796616:A4V09_RS03825
uniprot id: A0A1C7I5U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1796616:A4V09 RS01120
gene id: 1796616:A4V09_RS01120
uniprot id: A0A1C7I4I5
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS06025
gene id: 1796616:A4V09_RS06025
uniprot id: A0A1C7I6Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796616:A4V09 RS15030
gene id: 1796616:A4V09_RS15030
uniprot id: A0A1C7IB77
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS05165
gene id: 1796616:A4V09_RS05165
uniprot id: A0A1C7I6E0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1796616:A4V09 RS23275
gene id: 1796616:A4V09_RS23275
uniprot id: A0A1C7IJQ3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1796616:A4V09 RS09000
gene id: 1796616:A4V09_RS09000
uniprot id: A0A1C7IA46
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1796616:A4V09 RS05415
gene id: 1796616:A4V09_RS05415
uniprot id: A0A1C7I6K0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1796616:A4V09 RS23455
gene id: 1796616:A4V09_RS23455
uniprot id: A0A1C7IHH9
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1796616:A4V09 RS12095
gene id: 1796616:A4V09_RS12095
uniprot id: A0A1C7I9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS02945
gene id: 1796616:A4V09_RS02945
uniprot id: A0A1C7I566
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1796616:A4V09 RS21190
gene id: 1796616:A4V09_RS21190
uniprot id: A0A1C7IE81
names: Similarity
messages: Belongs to the WXG100 family.

1796616:A4V09 RS20135
gene id: 1796616:A4V09_RS20135
uniprot id: A0A1C7IDL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1796616:A4V09 RS05100
gene id: 1796616:A4V09_RS05100
uniprot id: A0A1C7I8A7
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1796616:A4V09 RS23905
gene id: 1796616:A4V09_RS23905
uniprot id: A0A1C7IHP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS19440
gene id: 1796616:A4V09_RS19440
uniprot id: A0A1C7IFI3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS05615
gene id: 1796616:A4V09_RS05615
uniprot id: A0A1C7I9Q3
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1796616:A4V09 RS19550
gene id: 1796616:A4V09_RS19550
uniprot id: A0A1C7IFK2
names: Similarity
messages: Belongs to the EamA transporter family.

1796616:A4V09 RS18065
gene id: 1796616:A4V09_RS18065
uniprot id: A0A1C7ICQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS07660
gene id: 1796616:A4V09_RS07660
uniprot id: A0A1C7II75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS17655
gene id: 1796616:A4V09_RS17655
uniprot id: A0A1C7IKU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1796616:A4V09 RS12760
gene id: 1796616:A4V09_RS12760
uniprot id: A0A1C7IEB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1796616:A4V09 RS21735
gene id: 1796616:A4V09_RS21735
uniprot id: A0A1C7IGP1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS12435
gene id: 1796616:A4V09_RS12435
uniprot id: A0A1C7I9X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13685
gene id: 1796616:A4V09_RS13685
uniprot id: A0A1C7IAJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1796616:A4V09 RS12205
gene id: 1796616:A4V09_RS12205
uniprot id: A0A1C7I9S7
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1796616:A4V09 RS03590
gene id: 1796616:A4V09_RS03590
uniprot id: A0A1C7I7U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Belongs to the AccA family.
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1796616:A4V09 RS02005
gene id: 1796616:A4V09_RS02005
uniprot id: A0A1C7I8S4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1796616:A4V09 RS18360
gene id: 1796616:A4V09_RS18360
uniprot id: A0A1C7IEN6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS12685
gene id: 1796616:A4V09_RS12685
uniprot id: A0A1C7IBX4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS16135
gene id: 1796616:A4V09_RS16135
uniprot id: A0A1C7IDV0
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1796616:A4V09 RS17660
gene id: 1796616:A4V09_RS17660
uniprot id: A0A1C7ICF4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS15530
gene id: 1796616:A4V09_RS15530
uniprot id: A0A1C7IBQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

1796616:A4V09 RS05160
gene id: 1796616:A4V09_RS05160
uniprot id: A0A1C7I6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1796616:A4V09 RS03215
gene id: 1796616:A4V09_RS03215
uniprot id: A0A1C7I5A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1796616:A4V09 RS15870
gene id: 1796616:A4V09_RS15870
uniprot id: A0A1C7IBM6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1796616:A4V09 RS01685
gene id: 1796616:A4V09_RS01685
uniprot id: A0A1C7I4Q1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796616:A4V09 RS10240
gene id: 1796616:A4V09_RS10240
uniprot id: A0A1C7I8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796616:A4V09 RS09210
gene id: 1796616:A4V09_RS09210
uniprot id: A0A1C7I8C1
names: Similarity
messages: Belongs to the ThiD family.

1796616:A4V09 RS11780
gene id: 1796616:A4V09_RS11780
uniprot id: A0A1C7I9S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

1796616:A4V09 RS10380
gene id: 1796616:A4V09_RS10380
uniprot id: A0A1C7I8X3
names: Similarity
messages: Belongs to the peptidase S16 family.

1796616:A4V09 RS22590
gene id: 1796616:A4V09_RS22590
uniprot id: A0A1C7IGP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1796616:A4V09 RS20345
gene id: 1796616:A4V09_RS20345
uniprot id: A0A1C7IG45
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796616:A4V09 RS23370
gene id: 1796616:A4V09_RS23370
uniprot id: A0A1C7IFC5
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS02895
gene id: 1796616:A4V09_RS02895
uniprot id: A0A1C7I557
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796616:A4V09 RS23875
gene id: 1796616:A4V09_RS23875
uniprot id: A0A1C7IFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1796616:A4V09 RS21335
gene id: 1796616:A4V09_RS21335
uniprot id: A0A1C7IIQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1796616:A4V09 RS10515
gene id: 1796616:A4V09_RS10515
uniprot id: A0A1C7I938
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1796616:A4V09 RS19835
gene id: 1796616:A4V09_RS19835
uniprot id: A0A1C7IDH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1796616:A4V09 RS11805
gene id: 1796616:A4V09_RS11805
uniprot id: A0A1C7ICZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1796616:A4V09 RS05835
gene id: 1796616:A4V09_RS05835
uniprot id: A0A1C7I9U5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS23205
gene id: 1796616:A4V09_RS23205
uniprot id: A0A1C7IFB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS20010
gene id: 1796616:A4V09_RS20010
uniprot id: A0A1C7IFY7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1796616:A4V09 RS19540
gene id: 1796616:A4V09_RS19540
uniprot id: A0A1C7IGN7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1796616:A4V09 RS15875
gene id: 1796616:A4V09_RS15875
uniprot id: A0A1C7IDI5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS10740
gene id: 1796616:A4V09_RS10740
uniprot id: A0A1C7IBH4
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

1796616:A4V09 RS00960
gene id: 1796616:A4V09_RS00960
uniprot id: A0A1C7I6A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1796616:A4V09 RS04225
gene id: 1796616:A4V09_RS04225
uniprot id: A0A1C7I7Q5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS09820
gene id: 1796616:A4V09_RS09820
uniprot id: A0A1C7IBW6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796616:A4V09 RS23005
gene id: 1796616:A4V09_RS23005
uniprot id: A0A1C7IGF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796616:A4V09 RS14530
gene id: 1796616:A4V09_RS14530
uniprot id: A0A1C7IEE0
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1796616:A4V09 RS11230
gene id: 1796616:A4V09_RS11230
uniprot id: A0A1C7IBP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS21060
gene id: 1796616:A4V09_RS21060
uniprot id: A0A1C7IGC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS02595
gene id: 1796616:A4V09_RS02595
uniprot id: A0A1C7I852
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1796616:A4V09 RS08875
gene id: 1796616:A4V09_RS08875
uniprot id: A0A1C7IAB2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS02580
gene id: 1796616:A4V09_RS02580
uniprot id: A0A1C7I549
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1796616:A4V09 RS08515
gene id: 1796616:A4V09_RS08515
uniprot id: A0A1C7IA37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1796616:A4V09 RS05380
gene id: 1796616:A4V09_RS05380
uniprot id: A0A1C7I8G7
names: Similarity
messages: Belongs to the CpsD/CapB family.

1796616:A4V09 RS09015
gene id: 1796616:A4V09_RS09015
uniprot id: A0A1C7I8E4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1796616:A4V09 RS05240
gene id: 1796616:A4V09_RS05240
uniprot id: A0A1C7I6C0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1796616:A4V09 RS17145
gene id: 1796616:A4V09_RS17145
uniprot id: A0A1C7IC75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1796616:A4V09 RS14485
gene id: 1796616:A4V09_RS14485
uniprot id: A0A1C7IB10
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1796616:A4V09 RS09245
gene id: 1796616:A4V09_RS09245
uniprot id: A0A1C7IAG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS04160
gene id: 1796616:A4V09_RS04160
uniprot id: A0A1C7I5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1796616:A4V09 RS04265
gene id: 1796616:A4V09_RS04265
uniprot id: A0A1C7I604
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1796616:A4V09 RS02390
gene id: 1796616:A4V09_RS02390
uniprot id: A0A1C7I786
names: Similarity
messages: Belongs to the EamA transporter family.

1796616:A4V09 RS12655
gene id: 1796616:A4V09_RS12655
uniprot id: A0A1C7IE88
names: Similarity
messages: Belongs to the carbamate kinase family.

1796616:A4V09 RS20585
gene id: 1796616:A4V09_RS20585
uniprot id: A0A1C7IG38
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS16630
gene id: 1796616:A4V09_RS16630
uniprot id: A0A1C7IDU6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1796616:A4V09 RS02625
gene id: 1796616:A4V09_RS02625
uniprot id: A0A1C7I736
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1796616:A4V09 RS15555
gene id: 1796616:A4V09_RS15555
uniprot id: A0A1C7IG87
names: Similarity
messages: Belongs to the peptidase S41A family.

1796616:A4V09 RS02995
gene id: 1796616:A4V09_RS02995
uniprot id: A0A1C7IHX2
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS20250
gene id: 1796616:A4V09_RS20250
uniprot id: A0A1C7IDZ7
names: Similarity
messages: Belongs to the ParB family.

1796616:A4V09 RS11295
gene id: 1796616:A4V09_RS11295
uniprot id: A0A1C7I9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1796616:A4V09 RS10400
gene id: 1796616:A4V09_RS10400
uniprot id: A0A1C7IC80
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1796616:A4V09 RS22220
gene id: 1796616:A4V09_RS22220
uniprot id: A0A1C7IJ65
names: Similarity
messages: Belongs to the CdaR family.

1796616:A4V09 RS02315
gene id: 1796616:A4V09_RS02315
uniprot id: A0A1C7IFP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS14035
gene id: 1796616:A4V09_RS14035
uniprot id: A0A1C7IAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS00150
gene id: 1796616:A4V09_RS00150
uniprot id: A0A1C7I656
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS14655
gene id: 1796616:A4V09_RS14655
uniprot id: A0A1C7IB33
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS07840
gene id: 1796616:A4V09_RS07840
uniprot id: A0A1C7I9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1796616:A4V09 RS02535
gene id: 1796616:A4V09_RS02535
uniprot id: A0A1C7I839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15575
gene id: 1796616:A4V09_RS15575
uniprot id: A0A1C7IFR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS08940
gene id: 1796616:A4V09_RS08940
uniprot id: A0A1C7I894
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1796616:A4V09 RS17500
gene id: 1796616:A4V09_RS17500
uniprot id: A0A1C7ICF9
names: Similarity
messages: Belongs to the CapA family.

1796616:A4V09 RS14885
gene id: 1796616:A4V09_RS14885
uniprot id: A0A1C7IB41
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS07795
gene id: 1796616:A4V09_RS07795
uniprot id: A0A1C7IAV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1796616:A4V09 RS08500
gene id: 1796616:A4V09_RS08500
uniprot id: A0A1C7IKG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1796616:A4V09 RS03565
gene id: 1796616:A4V09_RS03565
uniprot id: A0A1C7I7D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1796616:A4V09 RS15190
gene id: 1796616:A4V09_RS15190
uniprot id: A0A1C7IBI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1796616:A4V09 RS15010
gene id: 1796616:A4V09_RS15010
uniprot id: A0A1C7IFG7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1796616:A4V09 RS02735
gene id: 1796616:A4V09_RS02735
uniprot id: A0A1C7I7E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1796616:A4V09 RS02635
gene id: 1796616:A4V09_RS02635
uniprot id: A0A1C7I560
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1796616:A4V09 RS20575
gene id: 1796616:A4V09_RS20575
uniprot id: A0A1C7IIB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1796616:A4V09 RS02120
gene id: 1796616:A4V09_RS02120
uniprot id: A0A1C7I502
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1796616:A4V09 RS10920
gene id: 1796616:A4V09_RS10920
uniprot id: A0A1C7I960
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1796616:A4V09 RS21405
gene id: 1796616:A4V09_RS21405
uniprot id: A0A1C7IE94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS15270
gene id: 1796616:A4V09_RS15270
uniprot id: A0A1C7IBB0
names: Similarity
messages: Belongs to the UPF0297 family.

1796616:A4V09 RS23465
gene id: 1796616:A4V09_RS23465
uniprot id: A0A1C7IF93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS00085
gene id: 1796616:A4V09_RS00085
uniprot id: A0A1C7I646
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS07235
gene id: 1796616:A4V09_RS07235
uniprot id: A0A1C7I7J1
names: Similarity
messages: Belongs to the membrane-bound acyltransferase family.

1796616:A4V09 RS06470
gene id: 1796616:A4V09_RS06470
uniprot id: A0A1C7I725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS00240
gene id: 1796616:A4V09_RS00240
uniprot id: A0A1C7I6Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13280
gene id: 1796616:A4V09_RS13280
uniprot id: A0A1C7IEK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1796616:A4V09 RS01520
gene id: 1796616:A4V09_RS01520
uniprot id: A0A1C7I4G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS03975
gene id: 1796616:A4V09_RS03975
uniprot id: A0A1C7I5U9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS01710
gene id: 1796616:A4V09_RS01710
uniprot id: A0A1C7I6M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS17285
gene id: 1796616:A4V09_RS17285
uniprot id: A0A1C7IGL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS05485
gene id: 1796616:A4V09_RS05485
uniprot id: A0A1C7I8I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1796616:A4V09 RS16330
gene id: 1796616:A4V09_RS16330
uniprot id: A0A1C7IDQ3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS22165
gene id: 1796616:A4V09_RS22165
uniprot id: A0A1C7IH05
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1796616:A4V09 RS20145
gene id: 1796616:A4V09_RS20145
uniprot id: A0A1C7IFI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1796616:A4V09 RS09940
gene id: 1796616:A4V09_RS09940
uniprot id: A0A1C7IAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12920
gene id: 1796616:A4V09_RS12920
uniprot id: A0A1C7IA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1796616:A4V09 RS14545
gene id: 1796616:A4V09_RS14545
uniprot id: A0A1C7IKP3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1796616:A4V09 RS06070
gene id: 1796616:A4V09_RS06070
uniprot id: A0A1C7I939
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1796616:A4V09 RS22745
gene id: 1796616:A4V09_RS22745
uniprot id: A0A1C7IF94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1796616:A4V09 RS15005
gene id: 1796616:A4V09_RS15005
uniprot id: A0A1C7IB90
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1796616:A4V09 RS15615
gene id: 1796616:A4V09_RS15615
uniprot id: A0A1C7IEY2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1796616:A4V09 RS00245
gene id: 1796616:A4V09_RS00245
uniprot id: A0A1C7I3V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1796616:A4V09 RS12975
gene id: 1796616:A4V09_RS12975
uniprot id: A0A1C7IAB1
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS03935
gene id: 1796616:A4V09_RS03935
uniprot id: A0A1C7I7R2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1796616:A4V09 RS14000
gene id: 1796616:A4V09_RS14000
uniprot id: A0A1C7IAS8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS09885
gene id: 1796616:A4V09_RS09885
uniprot id: A0A1C7IB17
names: Similarity
messages: Belongs to the FBPase class 3 family.

1796616:A4V09 RS15990
gene id: 1796616:A4V09_RS15990
uniprot id: A0A1C7IBP4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1796616:A4V09 RS21400
gene id: 1796616:A4V09_RS21400
uniprot id: A0A1C7IEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1796616:A4V09 RS04905
gene id: 1796616:A4V09_RS04905
uniprot id: A0A1C7I878
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1796616:A4V09 RS02195
gene id: 1796616:A4V09_RS02195
uniprot id: A0A1C7I7X5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1796616:A4V09 RS03280
gene id: 1796616:A4V09_RS03280
uniprot id: A0A1C7I5D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS21605
gene id: 1796616:A4V09_RS21605
uniprot id: A0A1C7IEH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1796616:A4V09 RS05955
gene id: 1796616:A4V09_RS05955
uniprot id: A0A1C7I6U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1796616:A4V09 RS03860
gene id: 1796616:A4V09_RS03860
uniprot id: A0A1C7I5T0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1796616:A4V09 RS03225
gene id: 1796616:A4V09_RS03225
uniprot id: A0A1C7I8H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS00020
gene id: 1796616:A4V09_RS00020
uniprot id: A0A1C7I637
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS10455
gene id: 1796616:A4V09_RS10455
uniprot id: A0A1C7I8Y5
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

1796616:A4V09 RS17115
gene id: 1796616:A4V09_RS17115
uniprot id: A0A1C7ICF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1796616:A4V09 RS12340
gene id: 1796616:A4V09_RS12340
uniprot id: A0A1C7IC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

1796616:A4V09 RS19405
gene id: 1796616:A4V09_RS19405
uniprot id: A0A1C7IF57
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS17505
gene id: 1796616:A4V09_RS17505
uniprot id: A0A1C7IE82
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS13810
gene id: 1796616:A4V09_RS13810
uniprot id: A0A1C7IAK0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1796616:A4V09 RS21040
gene id: 1796616:A4V09_RS21040
uniprot id: A0A1C7IE52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS03715
gene id: 1796616:A4V09_RS03715
uniprot id: A0A1C7I5P3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1796616:A4V09 RS05140
gene id: 1796616:A4V09_RS05140
uniprot id: A0A1C7I6F5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1796616:A4V09 RS16530
gene id: 1796616:A4V09_RS16530
uniprot id: A0A1C7IG80
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1796616:A4V09 RS07955
gene id: 1796616:A4V09_RS07955
uniprot id: A0A1C7IAY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1796616:A4V09 RS06745
gene id: 1796616:A4V09_RS06745
uniprot id: A0A1C7I777
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1796616:A4V09 RS15375
gene id: 1796616:A4V09_RS15375
uniprot id: A0A1C7IEU1
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS13845
gene id: 1796616:A4V09_RS13845
uniprot id: A0A1C7IAU2
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS16585
gene id: 1796616:A4V09_RS16585
uniprot id: A0A1C7IG90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20290
gene id: 1796616:A4V09_RS20290
uniprot id: A0A1C7IG27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15715
gene id: 1796616:A4V09_RS15715
uniprot id: A0A1C7IBJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1796616:A4V09 RS05685
gene id: 1796616:A4V09_RS05685
uniprot id: A0A1C7IAL3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1796616:A4V09 RS11030
gene id: 1796616:A4V09_RS11030
uniprot id: A0A1C7ICK0
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS23330
gene id: 1796616:A4V09_RS23330
uniprot id: A0A1C7IFD2
names: Similarity
messages: Belongs to the YoeB family.

1796616:A4V09 RS18465
gene id: 1796616:A4V09_RS18465
uniprot id: A0A1C7IGD8
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1796616:A4V09 RS17680
gene id: 1796616:A4V09_RS17680
uniprot id: A0A1C7IFZ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS03820
gene id: 1796616:A4V09_RS03820
uniprot id: A0A1C7I7P4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1796616:A4V09 RS04540
gene id: 1796616:A4V09_RS04540
uniprot id: A0A1C7I657
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1796616:A4V09 RS23810
gene id: 1796616:A4V09_RS23810
uniprot id: A0A1C7IJ73
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1796616:A4V09 RS21560
gene id: 1796616:A4V09_RS21560
uniprot id: A0A1C7IIU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1796616:A4V09 RS23915
gene id: 1796616:A4V09_RS23915
uniprot id: A0A1C7IFF6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS06135
gene id: 1796616:A4V09_RS06135
uniprot id: A0A1C7I6W3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1796616:A4V09 RS16455
gene id: 1796616:A4V09_RS16455
uniprot id: A0A1C7IFD8
names: Similarity
messages: Belongs to the peptidase M18 family.

1796616:A4V09 RS00490
gene id: 1796616:A4V09_RS00490
uniprot id: A0A1C7I623
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS06120
gene id: 1796616:A4V09_RS06120
uniprot id: A0A1C7I953
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1796616:A4V09 RS06930
gene id: 1796616:A4V09_RS06930
uniprot id: A0A1C7IAG2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1796616:A4V09 RS22800
gene id: 1796616:A4V09_RS22800
uniprot id: A0A1C7IEX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1796616:A4V09 RS04340
gene id: 1796616:A4V09_RS04340
uniprot id: A0A1C7I933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS09900
gene id: 1796616:A4V09_RS09900
uniprot id: A0A1C7I8M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1796616:A4V09 RS11150
gene id: 1796616:A4V09_RS11150
uniprot id: A0A1C7I9A5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1796616:A4V09 RS13540
gene id: 1796616:A4V09_RS13540
uniprot id: A0A1C7ICM1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1796616:A4V09 RS23815
gene id: 1796616:A4V09_RS23815
uniprot id: A0A1C7IFH2
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS23080
gene id: 1796616:A4V09_RS23080
uniprot id: A0A1C7IIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1796616:A4V09 RS05950
gene id: 1796616:A4V09_RS05950
uniprot id: A0A1C7I6Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1796616:A4V09 RS01955
gene id: 1796616:A4V09_RS01955
uniprot id: A0A1C7I706
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1796616:A4V09 RS05675
gene id: 1796616:A4V09_RS05675
uniprot id: A0A1C7I6K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1796616:A4V09 RS04590
gene id: 1796616:A4V09_RS04590
uniprot id: A0A1C7I977
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1796616:A4V09 RS03870
gene id: 1796616:A4V09_RS03870
uniprot id: A0A1C7I9Q1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS11060
gene id: 1796616:A4V09_RS11060
uniprot id: A0A1C7IBC3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS23095
gene id: 1796616:A4V09_RS23095
uniprot id: A0A1C7IJM4
names: Similarity
messages: Belongs to the UPF0735 family.

1796616:A4V09 RS23070
gene id: 1796616:A4V09_RS23070
uniprot id: A0A1C7IF79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1796616:A4V09 RS01655
gene id: 1796616:A4V09_RS01655
uniprot id: A0A1C7I4S8
names: Similarity
messages: Belongs to the EamA transporter family.

1796616:A4V09 RS03995
gene id: 1796616:A4V09_RS03995
uniprot id: A0A1C7I5X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1796616:A4V09 RS06320
gene id: 1796616:A4V09_RS06320
uniprot id: A0A1C7I6W9
names: Subcellular Location Annotation
messages: Bacterial microcompartment

1796616:A4V09 RS22955
gene id: 1796616:A4V09_RS22955
uniprot id: A0A1C7IF59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15680
gene id: 1796616:A4V09_RS15680
uniprot id: A0A1C7IBK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1796616:A4V09 RS18370
gene id: 1796616:A4V09_RS18370
uniprot id: A0A1C7ICT1
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1796616:A4V09 RS00455
gene id: 1796616:A4V09_RS00455
uniprot id: A0A1C7I3W5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS10410
gene id: 1796616:A4V09_RS10410
uniprot id: A0A1C7I920
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1796616:A4V09 RS12515
gene id: 1796616:A4V09_RS12515
uniprot id: A0A1C7IA60
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS21725
gene id: 1796616:A4V09_RS21725
uniprot id: A0A1C7IIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1796616:A4V09 RS15140
gene id: 1796616:A4V09_RS15140
uniprot id: A0A1C7IB93
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS05080
gene id: 1796616:A4V09_RS05080
uniprot id: A0A1C7I6E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1796616:A4V09 RS04920
gene id: 1796616:A4V09_RS04920
uniprot id: A0A1C7II37
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1796616:A4V09 RS09385
gene id: 1796616:A4V09_RS09385
uniprot id: A0A1C7I8E9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1796616:A4V09 RS23440
gene id: 1796616:A4V09_RS23440
uniprot id: A0A1C7IFF0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796616:A4V09 RS02270
gene id: 1796616:A4V09_RS02270
uniprot id: A0A1C7I8X6
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS18040
gene id: 1796616:A4V09_RS18040
uniprot id: A0A1C7IES8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS11265
gene id: 1796616:A4V09_RS11265
uniprot id: A0A1C7I9B8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1796616:A4V09 RS17035
gene id: 1796616:A4V09_RS17035
uniprot id: A0A1C7IC54
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1796616:A4V09 RS08935
gene id: 1796616:A4V09_RS08935
uniprot id: A0A1C7I8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1796616:A4V09 RS01305
gene id: 1796616:A4V09_RS01305
uniprot id: A0A1C7I6F4
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1796616:A4V09 RS05820
gene id: 1796616:A4V09_RS05820
uniprot id: A0A1C7I6Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1796616:A4V09 RS06045
gene id: 1796616:A4V09_RS06045
uniprot id: A0A1C7I9Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796616:A4V09 RS10625
gene id: 1796616:A4V09_RS10625
uniprot id: A0A1C7IBF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15785
gene id: 1796616:A4V09_RS15785
uniprot id: A0A1C7IBM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1796616:A4V09 RS01045
gene id: 1796616:A4V09_RS01045
uniprot id: A0A1C7I6K6
names: Similarity
messages: Belongs to the polypeptide deformylase family.

1796616:A4V09 RS12650
gene id: 1796616:A4V09_RS12650
uniprot id: A0A1C7IA48
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1796616:A4V09 RS05020
gene id: 1796616:A4V09_RS05020
uniprot id: A0A1C7I678
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796616:A4V09 RS17750
gene id: 1796616:A4V09_RS17750
uniprot id: A0A1C7ICH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1796616:A4V09 RS12010
gene id: 1796616:A4V09_RS12010
uniprot id: A0A1C7I9S5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1796616:A4V09 RS12885
gene id: 1796616:A4V09_RS12885
uniprot id: A0A1C7ICA1
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS21235
gene id: 1796616:A4V09_RS21235
uniprot id: A0A1C7IEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1796616:A4V09 RS20475
gene id: 1796616:A4V09_RS20475
uniprot id: A0A1C7IDT3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1796616:A4V09 RS15380
gene id: 1796616:A4V09_RS15380
uniprot id: A0A1C7IBD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1796616:A4V09 RS12175
gene id: 1796616:A4V09_RS12175
uniprot id: A0A1C7IBY1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796616:A4V09 RS09240
gene id: 1796616:A4V09_RS09240
uniprot id: A0A1C7IAS0
names: Similarity
messages: Belongs to the ArsC family.

1796616:A4V09 RS21025
gene id: 1796616:A4V09_RS21025
uniprot id: A0A1C7IE51
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1796616:A4V09 RS20340
gene id: 1796616:A4V09_RS20340
uniprot id: A0A1C7II71
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1796616:A4V09 RS22780
gene id: 1796616:A4V09_RS22780
uniprot id: A0A1C7IJG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS18230
gene id: 1796616:A4V09_RS18230
uniprot id: A0A1C7ICQ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1796616:A4V09 RS21395
gene id: 1796616:A4V09_RS21395
uniprot id: A0A1C7IGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1796616:A4V09 RS06040
gene id: 1796616:A4V09_RS06040
uniprot id: A0A1C7I8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796616:A4V09 RS08915
gene id: 1796616:A4V09_RS08915
uniprot id: A0A1C7ICB8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1796616:A4V09 RS20965
gene id: 1796616:A4V09_RS20965
uniprot id: A0A1C7IE17
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1796616:A4V09 RS23365
gene id: 1796616:A4V09_RS23365
uniprot id: A0A1C7IF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1796616:A4V09 RS15265
gene id: 1796616:A4V09_RS15265
uniprot id: A0A1C7IIE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1796616:A4V09 RS06580
gene id: 1796616:A4V09_RS06580
uniprot id: A0A1C7I943
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1796616:A4V09 RS16365
gene id: 1796616:A4V09_RS16365
uniprot id: A0A1C7IDZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS17720
gene id: 1796616:A4V09_RS17720
uniprot id: A0A1C7ICQ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796616:A4V09 RS15230
gene id: 1796616:A4V09_RS15230
uniprot id: A0A1C7IDN5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1796616:A4V09 RS01535
gene id: 1796616:A4V09_RS01535
uniprot id: A0A1C7I6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS21540
gene id: 1796616:A4V09_RS21540
uniprot id: A0A1C7IGE2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS21625
gene id: 1796616:A4V09_RS21625
uniprot id: A0A1C7IEP7
names: Similarity
messages: Belongs to the thioredoxin family.

1796616:A4V09 RS02415
gene id: 1796616:A4V09_RS02415
uniprot id: A0A1C7I6S5
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1796616:A4V09 RS23310
gene id: 1796616:A4V09_RS23310
uniprot id: A0A1C7IIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15260
gene id: 1796616:A4V09_RS15260
uniprot id: A0A1C7IES3
names: Similarity
messages: Belongs to the UPF0473 family.

1796616:A4V09 RS15315
gene id: 1796616:A4V09_RS15315
uniprot id: A0A1C7IET6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1796616:A4V09 RS02200
gene id: 1796616:A4V09_RS02200
uniprot id: A0A1C7I4U2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1796616:A4V09 RS06515
gene id: 1796616:A4V09_RS06515
uniprot id: A0A1C7I931
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1796616:A4V09 RS11260
gene id: 1796616:A4V09_RS11260
uniprot id: A0A1C7ICN4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1796616:A4V09 RS06590
gene id: 1796616:A4V09_RS06590
uniprot id: A0A1C7I744
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1796616:A4V09 RS02300
gene id: 1796616:A4V09_RS02300
uniprot id: A0A1C7I6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1796616:A4V09 RS03125
gene id: 1796616:A4V09_RS03125
uniprot id: A0A1C7I5F5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1796616:A4V09 RS04455
gene id: 1796616:A4V09_RS04455
uniprot id: A0A1C7I5U7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1796616:A4V09 RS09985
gene id: 1796616:A4V09_RS09985
uniprot id: A0A1C7I8U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS12615
gene id: 1796616:A4V09_RS12615
uniprot id: A0A1C7IG12
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1796616:A4V09 RS12270
gene id: 1796616:A4V09_RS12270
uniprot id: A0A1C7IC73
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1796616:A4V09 RS10445
gene id: 1796616:A4V09_RS10445
uniprot id: A0A1C7IAT1
names: Similarity
messages: Belongs to the class-I fumarase family.

1796616:A4V09 RS08550
gene id: 1796616:A4V09_RS08550
uniprot id: A0A1C7I7Z7
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1796616:A4V09 RS18085
gene id: 1796616:A4V09_RS18085
uniprot id: A0A1C7ICM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1796616:A4V09 RS23145
gene id: 1796616:A4V09_RS23145
uniprot id: A0A1C7IFA3
names: Similarity
messages: Belongs to the peptidase M24B family.

1796616:A4V09 RS18020
gene id: 1796616:A4V09_RS18020
uniprot id: A0A1C7ICL5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS19000
gene id: 1796616:A4V09_RS19000
uniprot id: A0A1C7ID38
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS12740
gene id: 1796616:A4V09_RS12740
uniprot id: A0A1C7IBY7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS01360
gene id: 1796616:A4V09_RS01360
uniprot id: A0A1C7I8G3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS14660
gene id: 1796616:A4V09_RS14660
uniprot id: A0A1C7IFB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1796616:A4V09 RS08045
gene id: 1796616:A4V09_RS08045
uniprot id: A0A1C7I7U1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1796616:A4V09 RS12715
gene id: 1796616:A4V09_RS12715
uniprot id: A0A1C7ICF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1796616:A4V09 RS10135
gene id: 1796616:A4V09_RS10135
uniprot id: A0A1C7I8S7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1796616:A4V09 RS22825
gene id: 1796616:A4V09_RS22825
uniprot id: A0A1C7IF44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS05395
gene id: 1796616:A4V09_RS05395
uniprot id: A0A1C7I6A1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1796616:A4V09 RS16285
gene id: 1796616:A4V09_RS16285
uniprot id: A0A1C7IBU1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS20185
gene id: 1796616:A4V09_RS20185
uniprot id: A0A1C7IFV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1796616:A4V09 RS05660
gene id: 1796616:A4V09_RS05660
uniprot id: A0A1C7I6F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1796616:A4V09 RS10690
gene id: 1796616:A4V09_RS10690
uniprot id: A0A1C7IBG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1796616:A4V09 RS10195
gene id: 1796616:A4V09_RS10195
uniprot id: A0A1C7ICY7
names: Similarity
messages: Belongs to the UPF0045 family.

1796616:A4V09 RS03785
gene id: 1796616:A4V09_RS03785
uniprot id: A0A1C7I7H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1796616:A4V09 RS19960
gene id: 1796616:A4V09_RS19960
uniprot id: A0A1C7IFX8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1796616:A4V09 RS08645
gene id: 1796616:A4V09_RS08645
uniprot id: A0A1C7IAF7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS08125
gene id: 1796616:A4V09_RS08125
uniprot id: A0A1C7I7U3
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

1796616:A4V09 RS00930
gene id: 1796616:A4V09_RS00930
uniprot id: A0A1C7I7B1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1796616:A4V09 RS02640
gene id: 1796616:A4V09_RS02640
uniprot id: A0A1C7I4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1796616:A4V09 RS10605
gene id: 1796616:A4V09_RS10605
uniprot id: A0A1C7ICC6
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1796616:A4V09 RS18750
gene id: 1796616:A4V09_RS18750
uniprot id: A0A1C7IHC8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796616:A4V09 RS17575
gene id: 1796616:A4V09_RS17575
uniprot id: A0A1C7ICE0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796616:A4V09 RS24050
gene id: 1796616:A4V09_RS24050
uniprot id: A0A1C7IFH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1796616:A4V09 RS05125
gene id: 1796616:A4V09_RS05125
uniprot id: A0A1C7I847
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS19775
gene id: 1796616:A4V09_RS19775
uniprot id: A0A1C7IFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS01615
gene id: 1796616:A4V09_RS01615
uniprot id: A0A1C7I6D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS23645
gene id: 1796616:A4V09_RS23645
uniprot id: A0A1C7IFD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1796616:A4V09 RS01920
gene id: 1796616:A4V09_RS01920
uniprot id: A0A1V0QEZ4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1796616:A4V09 RS15500
gene id: 1796616:A4V09_RS15500
uniprot id: A0A1C7IG93
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS04170
gene id: 1796616:A4V09_RS04170
uniprot id: A0A1C7I7P5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1796616:A4V09 RS18735
gene id: 1796616:A4V09_RS18735
uniprot id: A0A1C7ICZ8
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS17425
gene id: 1796616:A4V09_RS17425
uniprot id: A0A1C7IEG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1796616:A4V09 RS01610
gene id: 1796616:A4V09_RS01610
uniprot id: A0A1C7I4G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13135
gene id: 1796616:A4V09_RS13135
uniprot id: A0A1C7IAH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS15765
gene id: 1796616:A4V09_RS15765
uniprot id: A0A1C7IBK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1796616:A4V09 RS23035
gene id: 1796616:A4V09_RS23035
uniprot id: A0A1C7IF83
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1796616:A4V09 RS19605
gene id: 1796616:A4V09_RS19605
uniprot id: A0A1C7IDN6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1796616:A4V09 RS14200
gene id: 1796616:A4V09_RS14200
uniprot id: A0A1C7IAS3
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS03450
gene id: 1796616:A4V09_RS03450
uniprot id: A0A1C7I8M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796616:A4V09 RS04025
gene id: 1796616:A4V09_RS04025
uniprot id: A0A1C7I5W6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1796616:A4V09 RS06755
gene id: 1796616:A4V09_RS06755
uniprot id: A0A1C7I8X9
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS06065
gene id: 1796616:A4V09_RS06065
uniprot id: A0A1C7IAT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1796616:A4V09 RS07945
gene id: 1796616:A4V09_RS07945
uniprot id: A0A1C7I7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1796616:A4V09 RS05000
gene id: 1796616:A4V09_RS05000
uniprot id: A0A1C7I634
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1796616:A4V09 RS10230
gene id: 1796616:A4V09_RS10230
uniprot id: A0A1C7IC50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS13555
gene id: 1796616:A4V09_RS13555
uniprot id: A0A1C7IAH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS20130
gene id: 1796616:A4V09_RS20130
uniprot id: A0A1C7IDX3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1796616:A4V09 RS20380
gene id: 1796616:A4V09_RS20380
uniprot id: A0A1C7IHC5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1796616:A4V09 RS02520
gene id: 1796616:A4V09_RS02520
uniprot id: A0A1C7I541
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1796616:A4V09 RS11245
gene id: 1796616:A4V09_RS11245
uniprot id: A0A1C7I9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS03905
gene id: 1796616:A4V09_RS03905
uniprot id: A0A1C7I7J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1796616:A4V09 RS00090
gene id: 1796616:A4V09_RS00090
uniprot id: A0A1C7I5W4
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1796616:A4V09 RS03880
gene id: 1796616:A4V09_RS03880
uniprot id: A0A1C7I7Q3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1796616:A4V09 RS21315
gene id: 1796616:A4V09_RS21315
uniprot id: A0A1C7IHX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1796616:A4V09 RS05780
gene id: 1796616:A4V09_RS05780
uniprot id: A0A1C7IFR9
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS14995
gene id: 1796616:A4V09_RS14995
uniprot id: A0A1C7IEM7
names: Similarity
messages: Belongs to the TelA family.

1796616:A4V09 RS21000
gene id: 1796616:A4V09_RS21000
uniprot id: A0A1C7IIJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS21250
gene id: 1796616:A4V09_RS21250
uniprot id: A0A1C7IKZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1796616:A4V09 RS21470
gene id: 1796616:A4V09_RS21470
uniprot id: A0A1C7IED1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1796616:A4V09 RS15795
gene id: 1796616:A4V09_RS15795
uniprot id: A0A1C7IDX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1796616:A4V09 RS05190
gene id: 1796616:A4V09_RS05190
uniprot id: A0A1C7I6A8
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

1796616:A4V09 RS11040
gene id: 1796616:A4V09_RS11040
uniprot id: A0A1C7I9C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1796616:A4V09 RS16390
gene id: 1796616:A4V09_RS16390
uniprot id: A0A1C7IFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1796616:A4V09 RS04685
gene id: 1796616:A4V09_RS04685
uniprot id: A0A1C7I842
names: Similarity
messages: Belongs to the hemerythrin family.

1796616:A4V09 RS06770
gene id: 1796616:A4V09_RS06770
uniprot id: A0A1C7I792
names: Similarity
messages: Belongs to the EamA transporter family.

1796616:A4V09 RS11520
gene id: 1796616:A4V09_RS11520
uniprot id: A0A1C7IBB3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS04515
gene id: 1796616:A4V09_RS04515
uniprot id: A0A1C7I641
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1796616:A4V09 RS07645
gene id: 1796616:A4V09_RS07645
uniprot id: A0A1C7I9Y4
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

1796616:A4V09 RS03855
gene id: 1796616:A4V09_RS03855
uniprot id: A0A1C7I5N4
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS22255
gene id: 1796616:A4V09_RS22255
uniprot id: A0A1C7IGI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1796616:A4V09 RS09200
gene id: 1796616:A4V09_RS09200
uniprot id: A0A1C7IA74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1796616:A4V09 RS16295
gene id: 1796616:A4V09_RS16295
uniprot id: A0A1C7IG44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS08000
gene id: 1796616:A4V09_RS08000
uniprot id: A0A1C7I7Q7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1796616:A4V09 RS07915
gene id: 1796616:A4V09_RS07915
uniprot id: A0A1C7IBS9
names: Similarity
messages: Belongs to the peptidase S8 family.

1796616:A4V09 RS02810
gene id: 1796616:A4V09_RS02810
uniprot id: A0A1C7I526
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1796616:A4V09 RS22175
gene id: 1796616:A4V09_RS22175
uniprot id: A0A1C7IGW6
names: Similarity
messages: Belongs to the DapA family.

1796616:A4V09 RS18235
gene id: 1796616:A4V09_RS18235
uniprot id: A0A1C7IGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13180
gene id: 1796616:A4V09_RS13180
uniprot id: A0A1C7ICF6
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

1796616:A4V09 RS01540
gene id: 1796616:A4V09_RS01540
uniprot id: A0A1C7I6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20485
gene id: 1796616:A4V09_RS20485
uniprot id: A0A1C7IGJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1796616:A4V09 RS11385
gene id: 1796616:A4V09_RS11385
uniprot id: A0A1C7IDL3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1796616:A4V09 RS15740
gene id: 1796616:A4V09_RS15740
uniprot id: A0A1C7IFU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1796616:A4V09 RS23705
gene id: 1796616:A4V09_RS23705
uniprot id: A0A1C7IFF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15355
gene id: 1796616:A4V09_RS15355
uniprot id: A0A1C7IBD5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1796616:A4V09 RS07040
gene id: 1796616:A4V09_RS07040
uniprot id: A0A1C7I930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1796616:A4V09 RS16975
gene id: 1796616:A4V09_RS16975
uniprot id: A0A1C7IFM5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS05230
gene id: 1796616:A4V09_RS05230
uniprot id: A0A1C7I864
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1796616:A4V09 RS14040
gene id: 1796616:A4V09_RS14040
uniprot id: A0A1C7ICK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12725
gene id: 1796616:A4V09_RS12725
uniprot id: A0A1C7IA94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS11135
gene id: 1796616:A4V09_RS11135
uniprot id: A0A1C7IBD6
names: Similarity
messages: Belongs to the GARS family.

1796616:A4V09 RS07710
gene id: 1796616:A4V09_RS07710
uniprot id: A0A1C7I7R7
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS21890
gene id: 1796616:A4V09_RS21890
uniprot id: A0A1C7IJ07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS23735
gene id: 1796616:A4V09_RS23735
uniprot id: A0A1C7IFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS14130
gene id: 1796616:A4V09_RS14130
uniprot id: A0A1C7IAR9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1796616:A4V09 RS10980
gene id: 1796616:A4V09_RS10980
uniprot id: A0A1C7I969
names: Similarity
messages: Belongs to the SfsA family.

1796616:A4V09 RS21475
gene id: 1796616:A4V09_RS21475
uniprot id: A0A1C7IG60
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1796616:A4V09 RS07965
gene id: 1796616:A4V09_RS07965
uniprot id: A0A1C7I7U8
names: Similarity
messages: Belongs to the RemA family.

1796616:A4V09 RS13150
gene id: 1796616:A4V09_RS13150
uniprot id: A0A1C7IC59
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1796616:A4V09 RS16120
gene id: 1796616:A4V09_RS16120
uniprot id: A0A1C7IBU0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1796616:A4V09 RS14445
gene id: 1796616:A4V09_RS14445
uniprot id: A0A1C7IAW8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1796616:A4V09 RS18280
gene id: 1796616:A4V09_RS18280
uniprot id: A0A1C7IEX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS22260
gene id: 1796616:A4V09_RS22260
uniprot id: A0A1C7IIE2
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1796616:A4V09 RS23015
gene id: 1796616:A4V09_RS23015
uniprot id: A0A1C7IGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1796616:A4V09 RS00295
gene id: 1796616:A4V09_RS00295
uniprot id: A0A1C7I700
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1796616:A4V09 RS10345
gene id: 1796616:A4V09_RS10345
uniprot id: A0A1C7I8W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS04670
gene id: 1796616:A4V09_RS04670
uniprot id: A0A1C7I677
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS12420
gene id: 1796616:A4V09_RS12420
uniprot id: A0A1C7IBS6
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1796616:A4V09 RS21375
gene id: 1796616:A4V09_RS21375
uniprot id: A0A1C7IEA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1796616:A4V09 RS04220
gene id: 1796616:A4V09_RS04220
uniprot id: A0A1C7I5Q7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1796616:A4V09 RS01585
gene id: 1796616:A4V09_RS01585
uniprot id: A0A1C7I6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1796616:A4V09 RS05965
gene id: 1796616:A4V09_RS05965
uniprot id: A0A1C7I923
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

1796616:A4V09 RS02240
gene id: 1796616:A4V09_RS02240
uniprot id: A0A1C7I4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1796616:A4V09 RS06425
gene id: 1796616:A4V09_RS06425
uniprot id: A0A1C7IA70
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796616:A4V09 RS07810
gene id: 1796616:A4V09_RS07810
uniprot id: A0A1C7IBQ7
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1796616:A4V09 RS16870
gene id: 1796616:A4V09_RS16870
uniprot id: A0A1C7IDY2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS04085
gene id: 1796616:A4V09_RS04085
uniprot id: A0A1C7I9U1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1796616:A4V09 RS13255
gene id: 1796616:A4V09_RS13255
uniprot id: A0A1C7IAC5
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1796616:A4V09 RS11885
gene id: 1796616:A4V09_RS11885
uniprot id: A0A1C7IBS8
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

1796616:A4V09 RS07865
gene id: 1796616:A4V09_RS07865
uniprot id: A0A1C7IBR7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1796616:A4V09 RS09755
gene id: 1796616:A4V09_RS09755
uniprot id: A0A1C7I8K0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS17475
gene id: 1796616:A4V09_RS17475
uniprot id: A0A1C7IEH5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1796616:A4V09 RS05750
gene id: 1796616:A4V09_RS05750
uniprot id: A0A1C7I8X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1796616:A4V09 RS13785
gene id: 1796616:A4V09_RS13785
uniprot id: A0A1C7IAT4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS08405
gene id: 1796616:A4V09_RS08405
uniprot id: A0A1C7I9T9
names: Similarity
messages: Belongs to the peptidase C40 family.

1796616:A4V09 RS13335
gene id: 1796616:A4V09_RS13335
uniprot id: A0A1C7ICR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1796616:A4V09 RS03380
gene id: 1796616:A4V09_RS03380
uniprot id: A0A1C7IFR3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1796616:A4V09 RS15915
gene id: 1796616:A4V09_RS15915
uniprot id: A0A1C7IBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1796616:A4V09 RS06095
gene id: 1796616:A4V09_RS06095
uniprot id: A0A1C7I8K9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1796616:A4V09 RS23725
gene id: 1796616:A4V09_RS23725
uniprot id: A0A1C7IHL9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS01095
gene id: 1796616:A4V09_RS01095
uniprot id: A0A1C7I491
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS08930
gene id: 1796616:A4V09_RS08930
uniprot id: A0A1C7IAC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS15255
gene id: 1796616:A4V09_RS15255
uniprot id: A0A1C7ID70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1796616:A4V09 RS02620
gene id: 1796616:A4V09_RS02620
uniprot id: A0A1C7I7C6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS14990
gene id: 1796616:A4V09_RS14990
uniprot id: A0A1C7ID24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1796616:A4V09 RS05590
gene id: 1796616:A4V09_RS05590
uniprot id: A0A1C7I8K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1796616:A4V09 RS01575
gene id: 1796616:A4V09_RS01575
uniprot id: A0A1C7I4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1796616:A4V09 RS16255
gene id: 1796616:A4V09_RS16255
uniprot id: A0A1C7IKS1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1796616:A4V09 RS13800
gene id: 1796616:A4V09_RS13800
uniprot id: A0A1C7ICH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1796616:A4V09 RS00935
gene id: 1796616:A4V09_RS00935
uniprot id: A0A1C7I474
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1796616:A4V09 RS00975
gene id: 1796616:A4V09_RS00975
uniprot id: A0A1C7I457
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1796616:A4V09 RS02870
gene id: 1796616:A4V09_RS02870
uniprot id: A0A1C7I595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS01560
gene id: 1796616:A4V09_RS01560
uniprot id: A0A1C7I6C8
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS03290
gene id: 1796616:A4V09_RS03290
uniprot id: A0A1C7I9G7
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS02765
gene id: 1796616:A4V09_RS02765
uniprot id: A0A1C7I884
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS16515
gene id: 1796616:A4V09_RS16515
uniprot id: A0A1C7IFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS03830
gene id: 1796616:A4V09_RS03830
uniprot id: A0A1C7I5R0
names: Similarity
messages: Belongs to the TlyA family.

1796616:A4V09 RS01735
gene id: 1796616:A4V09_RS01735
uniprot id: A0A1C7IFS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1796616:A4V09 RS18210
gene id: 1796616:A4V09_RS18210
uniprot id: A0A1C7IH21
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1796616:A4V09 RS12860
gene id: 1796616:A4V09_RS12860
uniprot id: A0A1C7IA43
names: Similarity
messages: Belongs to the ribulokinase family.

1796616:A4V09 RS13455
gene id: 1796616:A4V09_RS13455
uniprot id: A0A1C7IAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS09220
gene id: 1796616:A4V09_RS09220
uniprot id: A0A1C7ICG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1796616:A4V09 RS10560
gene id: 1796616:A4V09_RS10560
uniprot id: A0A1C7I902
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1796616:A4V09 RS10010
gene id: 1796616:A4V09_RS10010
uniprot id: A0A1C7I8Q1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1796616:A4V09 RS02815
gene id: 1796616:A4V09_RS02815
uniprot id: A0A1C7I6Z7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13795
gene id: 1796616:A4V09_RS13795
uniprot id: A0A1C7IAL6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1796616:A4V09 RS06030
gene id: 1796616:A4V09_RS06030
uniprot id: A0A1C7I6U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796616:A4V09 RS23850
gene id: 1796616:A4V09_RS23850
uniprot id: A0A1C7IIB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS22850
gene id: 1796616:A4V09_RS22850
uniprot id: A0A1C7IEY9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1796616:A4V09 RS00140
gene id: 1796616:A4V09_RS00140
uniprot id: A0A1C7I400
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1796616:A4V09 RS05430
gene id: 1796616:A4V09_RS05430
uniprot id: A0A1C7I8H6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1796616:A4V09 RS21365
gene id: 1796616:A4V09_RS21365
uniprot id: A0A1C7IG39
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS16010
gene id: 1796616:A4V09_RS16010
uniprot id: A0A1C7IBR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS07920
gene id: 1796616:A4V09_RS07920
uniprot id: A0A1C7IA34
names: Similarity
messages: Belongs to the peptidase S8 family.

1796616:A4V09 RS05995
gene id: 1796616:A4V09_RS05995
uniprot id: A0A1C7I9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1796616:A4V09 RS04765
gene id: 1796616:A4V09_RS04765
uniprot id: A0A1C7I640
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS15700
gene id: 1796616:A4V09_RS15700
uniprot id: A0A1C7IDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1796616:A4V09 RS13275
gene id: 1796616:A4V09_RS13275
uniprot id: A0A1C7IAF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS18125
gene id: 1796616:A4V09_RS18125
uniprot id: A0A1C7ICR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1796616:A4V09 RS12450
gene id: 1796616:A4V09_RS12450
uniprot id: A0A1C7ICA6
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS02985
gene id: 1796616:A4V09_RS02985
uniprot id: A0A1C7I562
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1796616:A4V09 RS21045
gene id: 1796616:A4V09_RS21045
uniprot id: A0A1C7IE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS08595
gene id: 1796616:A4V09_RS08595
uniprot id: A0A1C7IA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1796616:A4V09 RS16505
gene id: 1796616:A4V09_RS16505
uniprot id: A0A1C7IDS7
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1796616:A4V09 RS22845
gene id: 1796616:A4V09_RS22845
uniprot id: A0A1C7IFA8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1796616:A4V09 RS19920
gene id: 1796616:A4V09_RS19920
uniprot id: A0A1C7IDI9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1796616:A4V09 RS00550
gene id: 1796616:A4V09_RS00550
uniprot id: A0A1C7I499
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS05705
gene id: 1796616:A4V09_RS05705
uniprot id: A0A1C7I6N4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS16450
gene id: 1796616:A4V09_RS16450
uniprot id: A0A1C7IDR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1796616:A4V09 RS22765
gene id: 1796616:A4V09_RS22765
uniprot id: A0A1C7IIP6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS02190
gene id: 1796616:A4V09_RS02190
uniprot id: A0A1C7I6N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1796616:A4V09 RS20685
gene id: 1796616:A4V09_RS20685
uniprot id: A0A1C7IIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS23560
gene id: 1796616:A4V09_RS23560
uniprot id: A0A1C7IJV6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1796616:A4V09 RS06035
gene id: 1796616:A4V09_RS06035
uniprot id: A0A1C7I6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796616:A4V09 RS15150
gene id: 1796616:A4V09_RS15150
uniprot id: A0A1C7IBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20470
gene id: 1796616:A4V09_RS20470
uniprot id: A0A1C7IE46
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1796616:A4V09 RS05475
gene id: 1796616:A4V09_RS05475
uniprot id: A0A1C7IAH4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1796616:A4V09 RS16605
gene id: 1796616:A4V09_RS16605
uniprot id: A0A1C7IK00
names: Similarity
messages: Belongs to the DtxR/MntR family.

1796616:A4V09 RS11140
gene id: 1796616:A4V09_RS11140
uniprot id: A0A1C7I9F0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS04635
gene id: 1796616:A4V09_RS04635
uniprot id: A0A1C7I691
names: Similarity
messages: Belongs to the peptidase S51 family.

1796616:A4V09 RS09420
gene id: 1796616:A4V09_RS09420
uniprot id: A0A1C7IG94
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS11195
gene id: 1796616:A4V09_RS11195
uniprot id: A0A1C7I9B3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1796616:A4V09 RS02465
gene id: 1796616:A4V09_RS02465
uniprot id: A0A1C7I531
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1796616:A4V09 RS00300
gene id: 1796616:A4V09_RS00300
uniprot id: A0A1C7I3W1
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS25280
gene id: 1796616:A4V09_RS25280
uniprot id: A0A1C7IBF4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS10340
gene id: 1796616:A4V09_RS10340
uniprot id: A0A1C7IC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS23040
gene id: 1796616:A4V09_RS23040
uniprot id: A0A1C7IJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1796616:A4V09 RS17355
gene id: 1796616:A4V09_RS17355
uniprot id: A0A1C7IEN2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1796616:A4V09 RS16495
gene id: 1796616:A4V09_RS16495
uniprot id: A0A1C7IBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1796616:A4V09 RS07210
gene id: 1796616:A4V09_RS07210
uniprot id: A0A1C7I7C1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS23020
gene id: 1796616:A4V09_RS23020
uniprot id: A0A1C7IGJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15815
gene id: 1796616:A4V09_RS15815
uniprot id: A0A1C7IBL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1796616:A4V09 RS12000
gene id: 1796616:A4V09_RS12000
uniprot id: A0A1C7I9X4
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1796616:A4V09 RS23105
gene id: 1796616:A4V09_RS23105
uniprot id: A0A1C7IHD0
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1796616:A4V09 RS15855
gene id: 1796616:A4V09_RS15855
uniprot id: A0A1C7IBV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS16910
gene id: 1796616:A4V09_RS16910
uniprot id: A0A1C7IC62
names: Similarity
messages: Belongs to the class-I fumarase family.

1796616:A4V09 RS11860
gene id: 1796616:A4V09_RS11860
uniprot id: A0A1C7ID03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1796616:A4V09 RS15630
gene id: 1796616:A4V09_RS15630
uniprot id: A0A1C7IFS4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1796616:A4V09 RS15665
gene id: 1796616:A4V09_RS15665
uniprot id: A0A1C7IDE1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1796616:A4V09 RS18865
gene id: 1796616:A4V09_RS18865
uniprot id: A0A1C7ID45
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS09165
gene id: 1796616:A4V09_RS09165
uniprot id: A0A1C7ICF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20545
gene id: 1796616:A4V09_RS20545
uniprot id: A0A1C7IIP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1796616:A4V09 RS14935
gene id: 1796616:A4V09_RS14935
uniprot id: A0A1C7IJX0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1796616:A4V09 RS15960
gene id: 1796616:A4V09_RS15960
uniprot id: A0A1C7IFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS14245
gene id: 1796616:A4V09_RS14245
uniprot id: A0A1C7ICP8
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS01715
gene id: 1796616:A4V09_RS01715
uniprot id: A0A1C7I4T6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1796616:A4V09 RS02115
gene id: 1796616:A4V09_RS02115
uniprot id: A0A1C7I6U7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1796616:A4V09 RS01210
gene id: 1796616:A4V09_RS01210
uniprot id: A0A1C7I665
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS05975
gene id: 1796616:A4V09_RS05975
uniprot id: A0A1C7I6X1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS22285
gene id: 1796616:A4V09_RS22285
uniprot id: A0A1C7IGY6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1796616:A4V09 RS06330
gene id: 1796616:A4V09_RS06330
uniprot id: A0A1C7IAY6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1796616:A4V09 RS04165
gene id: 1796616:A4V09_RS04165
uniprot id: A0A1C7I5Q2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1796616:A4V09 RS05665
gene id: 1796616:A4V09_RS05665
uniprot id: A0A1C7I8D7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1796616:A4V09 RS19015
gene id: 1796616:A4V09_RS19015
uniprot id: A0A1C7IFH1
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS22505
gene id: 1796616:A4V09_RS22505
uniprot id: A0A1C7IEY3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1796616:A4V09 RS20005
gene id: 1796616:A4V09_RS20005
uniprot id: A0A1C7II15
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1796616:A4V09 RS14745
gene id: 1796616:A4V09_RS14745
uniprot id: A0A1C7IB24
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796616:A4V09 RS12520
gene id: 1796616:A4V09_RS12520
uniprot id: A0A1C7I9Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1796616:A4V09 RS05915
gene id: 1796616:A4V09_RS05915
uniprot id: A0A1C7I8R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS07665
gene id: 1796616:A4V09_RS07665
uniprot id: A0A1C7I7M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS11975
gene id: 1796616:A4V09_RS11975
uniprot id: A0A1C7I9N6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

1796616:A4V09 RS01440
gene id: 1796616:A4V09_RS01440
uniprot id: A0A1C7I6R5
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

1796616:A4V09 RS10015
gene id: 1796616:A4V09_RS10015
uniprot id: A0A1C7I8P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS05385
gene id: 1796616:A4V09_RS05385
uniprot id: A0A1C7I6L4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS23180
gene id: 1796616:A4V09_RS23180
uniprot id: A0A1C7IF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13670
gene id: 1796616:A4V09_RS13670
uniprot id: A0A1C7ICN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS01705
gene id: 1796616:A4V09_RS01705
uniprot id: A0A1C7I6W2
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

1796616:A4V09 RS08480
gene id: 1796616:A4V09_RS08480
uniprot id: A0A1C7I9U7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS06975
gene id: 1796616:A4V09_RS06975
uniprot id: A0A1C7I924
names: Similarity
messages: Belongs to the transpeptidase family.

1796616:A4V09 RS11690
gene id: 1796616:A4V09_RS11690
uniprot id: A0A1C7ICW5
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS01395
gene id: 1796616:A4V09_RS01395
uniprot id: A0A1C7IHG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1796616:A4V09 RS02280
gene id: 1796616:A4V09_RS02280
uniprot id: A0A1C7I6X7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1796616:A4V09 RS12115
gene id: 1796616:A4V09_RS12115
uniprot id: A0A1C7I9Z2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1796616:A4V09 RS02820
gene id: 1796616:A4V09_RS02820
uniprot id: A0A1C7I893
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS14665
gene id: 1796616:A4V09_RS14665
uniprot id: A0A1C7IDE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1796616:A4V09 RS07360
gene id: 1796616:A4V09_RS07360
uniprot id: A0A1C7I977
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1796616:A4V09 RS20400
gene id: 1796616:A4V09_RS20400
uniprot id: A0A1C7IG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS14975
gene id: 1796616:A4V09_RS14975
uniprot id: A0A1C7IBD8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1796616:A4V09 RS08150
gene id: 1796616:A4V09_RS08150
uniprot id: A0A1C7I7Z3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS14265
gene id: 1796616:A4V09_RS14265
uniprot id: A0A1C7IAX9
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS22900
gene id: 1796616:A4V09_RS22900
uniprot id: A0A1C7IEZ9
names: Similarity
messages: Belongs to the barstar family.

1796616:A4V09 RS18090
gene id: 1796616:A4V09_RS18090
uniprot id: A0A1C7ICR5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1796616:A4V09 RS12510
gene id: 1796616:A4V09_RS12510
uniprot id: A0A1C7IC33
names: Similarity
messages: Belongs to the pyruvate kinase family.

1796616:A4V09 RS15295
gene id: 1796616:A4V09_RS15295
uniprot id: A0A1C7IBK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1796616:A4V09 RS07870
gene id: 1796616:A4V09_RS07870
uniprot id: A0A1C7IA25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1796616:A4V09 RS13020
gene id: 1796616:A4V09_RS13020
uniprot id: A0A1C7IDL1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1796616:A4V09 RS03835
gene id: 1796616:A4V09_RS03835
uniprot id: A0A1C7I5K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS02745
gene id: 1796616:A4V09_RS02745
uniprot id: A0A1C7I5C0
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

1796616:A4V09 RS17865
gene id: 1796616:A4V09_RS17865
uniprot id: A0A1C7ICM2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS19995
gene id: 1796616:A4V09_RS19995
uniprot id: A0A1C7IDM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1796616:A4V09 RS19975
gene id: 1796616:A4V09_RS19975
uniprot id: A0A1C7IDJ3
names: Similarity
messages: Belongs to the Fur family.

1796616:A4V09 RS11200
gene id: 1796616:A4V09_RS11200
uniprot id: A0A1C7I9B1
names: Subcellular Location Annotation
messages: Cytoplasm

1796616:A4V09 RS07120
gene id: 1796616:A4V09_RS07120
uniprot id: A0A1C7I9E6
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS23545
gene id: 1796616:A4V09_RS23545
uniprot id: A0A1C7IJ34
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1796616:A4V09 RS20115
gene id: 1796616:A4V09_RS20115
uniprot id: A0A1C7II22
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1796616:A4V09 RS03250
gene id: 1796616:A4V09_RS03250
uniprot id: A0A1C7I7F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15350
gene id: 1796616:A4V09_RS15350
uniprot id: A0A1C7IBL5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1796616:A4V09 RS09875
gene id: 1796616:A4V09_RS09875
uniprot id: A0A1C7I8S8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1796616:A4V09 RS04400
gene id: 1796616:A4V09_RS04400
uniprot id: A0A1C7I944
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1796616:A4V09 RS04210
gene id: 1796616:A4V09_RS04210
uniprot id: A0A1C7I626
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS11115
gene id: 1796616:A4V09_RS11115
uniprot id: A0A1C7I989
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1796616:A4V09 RS05625
gene id: 1796616:A4V09_RS05625
uniprot id: A0A1C7I6N7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1796616:A4V09 RS21525
gene id: 1796616:A4V09_RS21525
uniprot id: A0A1C7IEB0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1796616:A4V09 RS15810
gene id: 1796616:A4V09_RS15810
uniprot id: A0A1C7IBK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1796616:A4V09 RS16675
gene id: 1796616:A4V09_RS16675
uniprot id: A0A1C7IC22
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1796616:A4V09 RS15730
gene id: 1796616:A4V09_RS15730
uniprot id: A0A1C7IBJ0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1796616:A4V09 RS07760
gene id: 1796616:A4V09_RS07760
uniprot id: A0A1C7IA02
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796616:A4V09 RS19825
gene id: 1796616:A4V09_RS19825
uniprot id: A0A1C7IFC8
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1796616:A4V09 RS02605
gene id: 1796616:A4V09_RS02605
uniprot id: A0A1C7I569
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1796616:A4V09 RS07020
gene id: 1796616:A4V09_RS07020
uniprot id: A0A1C7I7E8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1796616:A4V09 RS17235
gene id: 1796616:A4V09_RS17235
uniprot id: A0A1C7IED4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1796616:A4V09 RS21440
gene id: 1796616:A4V09_RS21440
uniprot id: A0A1C7IEE7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1796616:A4V09 RS02455
gene id: 1796616:A4V09_RS02455
uniprot id: A0A1C7IHZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1796616:A4V09 RS04755
gene id: 1796616:A4V09_RS04755
uniprot id: A0A1C7I7Y9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1796616:A4V09 RS10205
gene id: 1796616:A4V09_RS10205
uniprot id: A0A1C7IAY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796616:A4V09 RS18675
gene id: 1796616:A4V09_RS18675
uniprot id: A0A1C7ICY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1796616:A4V09 RS05480
gene id: 1796616:A4V09_RS05480
uniprot id: A0A1C7I8S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1796616:A4V09 RS20500
gene id: 1796616:A4V09_RS20500
uniprot id: A0A1C7IDV6
names: Similarity
messages: Belongs to the peptidase S11 family.

1796616:A4V09 RS07530
gene id: 1796616:A4V09_RS07530
uniprot id: A0A1C7I7N2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS15020
gene id: 1796616:A4V09_RS15020
uniprot id: A0A1C7IDC3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS21485
gene id: 1796616:A4V09_RS21485
uniprot id: A0A1C7IEC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1796616:A4V09 RS20595
gene id: 1796616:A4V09_RS20595
uniprot id: A0A1C7IE66
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1796616:A4V09 RS15710
gene id: 1796616:A4V09_RS15710
uniprot id: A0A1C7IBI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1796616:A4V09 RS11625
gene id: 1796616:A4V09_RS11625
uniprot id: A0A1C7I9K7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1796616:A4V09 RS10055
gene id: 1796616:A4V09_RS10055
uniprot id: A0A1C7I8W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1796616:A4V09 RS15455
gene id: 1796616:A4V09_RS15455
uniprot id: A0A1C7IG50
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS09260
gene id: 1796616:A4V09_RS09260
uniprot id: A0A1C7I8C6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS19515
gene id: 1796616:A4V09_RS19515
uniprot id: A0A1C7IF76
names: Similarity
messages: Belongs to the FGGY kinase family.

1796616:A4V09 RS16835
gene id: 1796616:A4V09_RS16835
uniprot id: A0A1C7IGD1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS00260
gene id: 1796616:A4V09_RS00260
uniprot id: A0A1C7I676
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS04965
gene id: 1796616:A4V09_RS04965
uniprot id: A0A1C7II03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796616:A4V09 RS15545
gene id: 1796616:A4V09_RS15545
uniprot id: A0A1C7IDC1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS04295
gene id: 1796616:A4V09_RS04295
uniprot id: A0A1C7I9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1796616:A4V09 RS06235
gene id: 1796616:A4V09_RS06235
uniprot id: A0A1C7I719
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15670
gene id: 1796616:A4V09_RS15670
uniprot id: A0A1C7IEZ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1796616:A4V09 RS15985
gene id: 1796616:A4V09_RS15985
uniprot id: A0A1C7IBN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1796616:A4V09 RS22190
gene id: 1796616:A4V09_RS22190
uniprot id: A0A1C7IEM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS05450
gene id: 1796616:A4V09_RS05450
uniprot id: A0A1C7I8A3
names: Similarity
messages: Belongs to the UPF0102 family.

1796616:A4V09 RS20465
gene id: 1796616:A4V09_RS20465
uniprot id: A0A1C7IG19
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1796616:A4V09 RS18275
gene id: 1796616:A4V09_RS18275
uniprot id: A0A1C7IF45
names: Similarity
messages: Belongs to the peptidase M20A family.

1796616:A4V09 RS09495
gene id: 1796616:A4V09_RS09495
uniprot id: A0A1C7I8G0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS23825
gene id: 1796616:A4V09_RS23825
uniprot id: A0A1C7IJZ3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1796616:A4V09 RS17825
gene id: 1796616:A4V09_RS17825
uniprot id: A0A1C7IEW3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1796616:A4V09 RS00285
gene id: 1796616:A4V09_RS00285
uniprot id: A0A1C7IHW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1796616:A4V09 RS11725
gene id: 1796616:A4V09_RS11725
uniprot id: A0A1C7I9R6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1796616:A4V09 RS04230
gene id: 1796616:A4V09_RS04230
uniprot id: A0A1C7I910
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1796616:A4V09 RS08630
gene id: 1796616:A4V09_RS08630
uniprot id: A0A1C7I822
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1796616:A4V09 RS23555
gene id: 1796616:A4V09_RS23555
uniprot id: A0A1C7IFH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1796616:A4V09 RS17310
gene id: 1796616:A4V09_RS17310
uniprot id: A0A1C7II39
names: Similarity
messages: Belongs to the peptidase M29 family.

1796616:A4V09 RS12080
gene id: 1796616:A4V09_RS12080
uniprot id: A0A1C7IBL3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1796616:A4V09 RS16340
gene id: 1796616:A4V09_RS16340
uniprot id: A0A1C7IBV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13745
gene id: 1796616:A4V09_RS13745
uniprot id: A0A1C7IAK3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1796616:A4V09 RS16065
gene id: 1796616:A4V09_RS16065
uniprot id: A0A1C7IBT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1796616:A4V09 RS05075
gene id: 1796616:A4V09_RS05075
uniprot id: A0A1C7I688
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1796616:A4V09 RS00945
gene id: 1796616:A4V09_RS00945
uniprot id: A0A1C7I899
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1796616:A4V09 RS02725
gene id: 1796616:A4V09_RS02725
uniprot id: A0A1C7I585
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS22365
gene id: 1796616:A4V09_RS22365
uniprot id: A0A1C7IES9
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS04325
gene id: 1796616:A4V09_RS04325
uniprot id: A0A1C7I7S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1796616:A4V09 RS05085
gene id: 1796616:A4V09_RS05085
uniprot id: A0A1C7IHM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1796616:A4V09 RS02540
gene id: 1796616:A4V09_RS02540
uniprot id: A0A1C7I500
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1796616:A4V09 RS16260
gene id: 1796616:A4V09_RS16260
uniprot id: A0A1C7IC29
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1796616:A4V09 RS16840
gene id: 1796616:A4V09_RS16840
uniprot id: A0A1C7IEF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1796616:A4V09 RS10845
gene id: 1796616:A4V09_RS10845
uniprot id: A0A1C7I949
names: Similarity
messages: Belongs to the UPF0597 family.

1796616:A4V09 RS08010
gene id: 1796616:A4V09_RS08010
uniprot id: A0A1C7IAZ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1796616:A4V09 RS08715
gene id: 1796616:A4V09_RS08715
uniprot id: A0A1C7I846
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS06315
gene id: 1796616:A4V09_RS06315
uniprot id: A0A1C7IA51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1796616:A4V09 RS17990
gene id: 1796616:A4V09_RS17990
uniprot id: A0A1C7IER8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1796616:A4V09 RS22110
gene id: 1796616:A4V09_RS22110
uniprot id: A0A1C7IGW0
names: Similarity
messages: Belongs to the IlvD/Edd family.

1796616:A4V09 RS03685
gene id: 1796616:A4V09_RS03685
uniprot id: A0A1C7I5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS22835
gene id: 1796616:A4V09_RS22835
uniprot id: A0A1C7IHC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS17045
gene id: 1796616:A4V09_RS17045
uniprot id: A0A1C7IC88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS09085
gene id: 1796616:A4V09_RS09085
uniprot id: A0A1C7I8F4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS05435
gene id: 1796616:A4V09_RS05435
uniprot id: A0A1C7I6M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12765
gene id: 1796616:A4V09_RS12765
uniprot id: A0A1C7ICG3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1796616:A4V09 RS13950
gene id: 1796616:A4V09_RS13950
uniprot id: A0A1C7IEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

1796616:A4V09 RS02665
gene id: 1796616:A4V09_RS02665
uniprot id: A0A1C7I947
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1796616:A4V09 RS20950
gene id: 1796616:A4V09_RS20950
uniprot id: A0A1C7IGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS14080
gene id: 1796616:A4V09_RS14080
uniprot id: A0A1C7IAQ9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1796616:A4V09 RS17935
gene id: 1796616:A4V09_RS17935
uniprot id: A0A1C7IEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS01550
gene id: 1796616:A4V09_RS01550
uniprot id: A0A1C7I4L8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1796616:A4V09 RS15735
gene id: 1796616:A4V09_RS15735
uniprot id: A0A1C7IBL6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1796616:A4V09 RS16560
gene id: 1796616:A4V09_RS16560
uniprot id: A0A1C7IDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS12015
gene id: 1796616:A4V09_RS12015
uniprot id: A0A1C7IBK4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS18100
gene id: 1796616:A4V09_RS18100
uniprot id: A0A1C7IF17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1796616:A4V09 RS07035
gene id: 1796616:A4V09_RS07035
uniprot id: A0A1C7I771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1796616:A4V09 RS06630
gene id: 1796616:A4V09_RS06630
uniprot id: A0A1C7I951
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS05115
gene id: 1796616:A4V09_RS05115
uniprot id: A0A1C7I650
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1796616:A4V09 RS21595
gene id: 1796616:A4V09_RS21595
uniprot id: A0A1C7II27
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1796616:A4V09 RS13205
gene id: 1796616:A4V09_RS13205
uniprot id: A0A1C7IC69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS21095
gene id: 1796616:A4V09_RS21095
uniprot id: A0A1C7IE59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1796616:A4V09 RS04680
gene id: 1796616:A4V09_RS04680
uniprot id: A0A1C7I8D4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS13665
gene id: 1796616:A4V09_RS13665
uniprot id: A0A1C7IJV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1796616:A4V09 RS04445
gene id: 1796616:A4V09_RS04445
uniprot id: A0A1C7I630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1796616:A4V09 RS07055
gene id: 1796616:A4V09_RS07055
uniprot id: A0A1C7I7E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1796616:A4V09 RS10805
gene id: 1796616:A4V09_RS10805
uniprot id: A0A1C7IBI2
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS00215
gene id: 1796616:A4V09_RS00215
uniprot id: A0A1C7I401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1796616:A4V09 RS12400
gene id: 1796616:A4V09_RS12400
uniprot id: A0A1C7IC12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796616:A4V09 RS03815
gene id: 1796616:A4V09_RS03815
uniprot id: A0A1C7I7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1796616:A4V09 RS16105
gene id: 1796616:A4V09_RS16105
uniprot id: A0A1C7IDL8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

1796616:A4V09 RS15845
gene id: 1796616:A4V09_RS15845
uniprot id: A0A1C7IDY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1796616:A4V09 RS20150
gene id: 1796616:A4V09_RS20150
uniprot id: A0A1C7IH81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1796616:A4V09 RS06805
gene id: 1796616:A4V09_RS06805
uniprot id: A0A1C7I8Y9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS22995
gene id: 1796616:A4V09_RS22995
uniprot id: A0A1C7IFE2
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS12750
gene id: 1796616:A4V09_RS12750
uniprot id: A0A1C7IA23
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1796616:A4V09 RS08660
gene id: 1796616:A4V09_RS08660
uniprot id: A0A1C7I837
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1796616:A4V09 RS04745
gene id: 1796616:A4V09_RS04745
uniprot id: A0A1C7I680
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS21255
gene id: 1796616:A4V09_RS21255
uniprot id: A0A1C7IG20
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS02645
gene id: 1796616:A4V09_RS02645
uniprot id: A0A1C7I6W6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1796616:A4V09 RS05445
gene id: 1796616:A4V09_RS05445
uniprot id: A0A1C7I6B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1796616:A4V09 RS14605
gene id: 1796616:A4V09_RS14605
uniprot id: A0A1C7IF97
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1796616:A4V09 RS18180
gene id: 1796616:A4V09_RS18180
uniprot id: A0A1C7ICS1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1796616:A4V09 RS14650
gene id: 1796616:A4V09_RS14650
uniprot id: A0A1C7IB05
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1796616:A4V09 RS23685
gene id: 1796616:A4V09_RS23685
uniprot id: A0A1C7IFH0
names: Similarity
messages: Belongs to the TPP enzyme family.

1796616:A4V09 RS17335
gene id: 1796616:A4V09_RS17335
uniprot id: A0A1C7IFT2
names: Similarity
messages: Belongs to the transpeptidase family.

1796616:A4V09 RS04815
gene id: 1796616:A4V09_RS04815
uniprot id: A0A1C7I7Z8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS23835
gene id: 1796616:A4V09_RS23835
uniprot id: A0A1C7IHS2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS00925
gene id: 1796616:A4V09_RS00925
uniprot id: A0A1C7I622
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1796616:A4V09 RS01380
gene id: 1796616:A4V09_RS01380
uniprot id: A0A1C7IFP7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS20125
gene id: 1796616:A4V09_RS20125
uniprot id: A0A1C7IFV0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1796616:A4V09 RS09700
gene id: 1796616:A4V09_RS09700
uniprot id: A0A1C7IBU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1796616:A4V09 RS05250
gene id: 1796616:A4V09_RS05250
uniprot id: A0A1C7IJJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1796616:A4V09 RS23775
gene id: 1796616:A4V09_RS23775
uniprot id: A0A1C7IHR4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1796616:A4V09 RS02425
gene id: 1796616:A4V09_RS02425
uniprot id: A0A1C7I4Y1
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS12445
gene id: 1796616:A4V09_RS12445
uniprot id: A0A1C7IE47
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS14830
gene id: 1796616:A4V09_RS14830
uniprot id: A0A1C7IB35
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1796616:A4V09 RS15195
gene id: 1796616:A4V09_RS15195
uniprot id: A0A1C7IBA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1796616:A4V09 RS11750
gene id: 1796616:A4V09_RS11750
uniprot id: A0A1C7ICX6
names: Similarity
messages: Belongs to the UPF0473 family.

1796616:A4V09 RS15720
gene id: 1796616:A4V09_RS15720
uniprot id: A0A1C7IDF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1796616:A4V09 RS00920
gene id: 1796616:A4V09_RS00920
uniprot id: A0A1C7I448
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1796616:A4V09 RS11620
gene id: 1796616:A4V09_RS11620
uniprot id: A0A1C7I9I8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1796616:A4V09 RS07030
gene id: 1796616:A4V09_RS07030
uniprot id: A0A1C7IFY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1796616:A4V09 RS16480
gene id: 1796616:A4V09_RS16480
uniprot id: A0A1C7IE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796616:A4V09 RS07535
gene id: 1796616:A4V09_RS07535
uniprot id: A0A1C7I7L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12590
gene id: 1796616:A4V09_RS12590
uniprot id: A0A1C7I9Z5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1796616:A4V09 RS05765
gene id: 1796616:A4V09_RS05765
uniprot id: A0A1C7I6P5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1796616:A4V09 RS19320
gene id: 1796616:A4V09_RS19320
uniprot id: A0A1C7IHP1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1796616:A4V09 RS10280
gene id: 1796616:A4V09_RS10280
uniprot id: A0A1C7IC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS11270
gene id: 1796616:A4V09_RS11270
uniprot id: A0A1C7I9F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1796616:A4V09 RS05775
gene id: 1796616:A4V09_RS05775
uniprot id: A0A1C7I8F7
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS06810
gene id: 1796616:A4V09_RS06810
uniprot id: A0A1C7IAE0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS00485
gene id: 1796616:A4V09_RS00485
uniprot id: A0A1C7I6B1
names: Similarity
messages: Belongs to the manganese catalase family.

1796616:A4V09 RS09635
gene id: 1796616:A4V09_RS09635
uniprot id: A0A1C7I8I1
names: Subcellular Location Annotation
messages: Cytoplasm

1796616:A4V09 RS17340
gene id: 1796616:A4V09_RS17340
uniprot id: A0A1C7ICA0
names: Subcellular Location Annotation
messages: Cytoplasm

1796616:A4V09 RS03950
gene id: 1796616:A4V09_RS03950
uniprot id: A0A1C7I5M8
names: Similarity
messages: Belongs to the peptidase C40 family.

1796616:A4V09 RS15760
gene id: 1796616:A4V09_RS15760
uniprot id: A0A1C7IBJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1796616:A4V09 RS20395
gene id: 1796616:A4V09_RS20395
uniprot id: A0A1C7II84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1796616:A4V09 RS01875
gene id: 1796616:A4V09_RS01875
uniprot id: A0A1C7I4N0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS03625
gene id: 1796616:A4V09_RS03625
uniprot id: A0A1C7I5J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS06880
gene id: 1796616:A4V09_RS06880
uniprot id: A0A1C7I762
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS13760
gene id: 1796616:A4V09_RS13760
uniprot id: A0A1C7IAJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1796616:A4V09 RS15660
gene id: 1796616:A4V09_RS15660
uniprot id: A0A1C7IBI8
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1796616:A4V09 RS16640
gene id: 1796616:A4V09_RS16640
uniprot id: A0A1C7IBZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1796616:A4V09 RS13930
gene id: 1796616:A4V09_RS13930
uniprot id: A0A1C7IE19
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1796616:A4V09 RS08640
gene id: 1796616:A4V09_RS08640
uniprot id: A0A1C7IC53
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS24015
gene id: 1796616:A4V09_RS24015
uniprot id: A0A1C7IL23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS08510
gene id: 1796616:A4V09_RS08510
uniprot id: A0A1C7IAD5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1796616:A4V09 RS00425
gene id: 1796616:A4V09_RS00425
uniprot id: A0A1C7I449
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1796616:A4V09 RS12820
gene id: 1796616:A4V09_RS12820
uniprot id: A0A1C7ICH4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS07825
gene id: 1796616:A4V09_RS07825
uniprot id: A0A1C7I7T4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS05825
gene id: 1796616:A4V09_RS05825
uniprot id: A0A1C7I6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1796616:A4V09 RS12625
gene id: 1796616:A4V09_RS12625
uniprot id: A0A1C7IA05
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1796616:A4V09 RS18695
gene id: 1796616:A4V09_RS18695
uniprot id: A0A1C7IF62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796616:A4V09 RS22250
gene id: 1796616:A4V09_RS22250
uniprot id: A0A1C7IES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1796616:A4V09 RS03325
gene id: 1796616:A4V09_RS03325
uniprot id: A0A1C7I5E4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS17545
gene id: 1796616:A4V09_RS17545
uniprot id: A0A1C7IEI6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1796616:A4V09 RS01410
gene id: 1796616:A4V09_RS01410
uniprot id: A0A1C7I696
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS21380
gene id: 1796616:A4V09_RS21380
uniprot id: A0A1C7IED9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1796616:A4V09 RS15570
gene id: 1796616:A4V09_RS15570
uniprot id: A0A1C7IGC4
names: Similarity
messages: Belongs to the CdaR family.

1796616:A4V09 RS03490
gene id: 1796616:A4V09_RS03490
uniprot id: A0A1C7I5F1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1796616:A4V09 RS05255
gene id: 1796616:A4V09_RS05255
uniprot id: A0A1C7IAD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1796616:A4V09 RS18285
gene id: 1796616:A4V09_RS18285
uniprot id: A0A1C7ID00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS04155
gene id: 1796616:A4V09_RS04155
uniprot id: A0A1C7I617
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS20745
gene id: 1796616:A4V09_RS20745
uniprot id: A0A1C7IGB9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS15825
gene id: 1796616:A4V09_RS15825
uniprot id: A0A1C7IF23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1796616:A4V09 RS13750
gene id: 1796616:A4V09_RS13750
uniprot id: A0A1C7ICG1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1796616:A4V09 RS02825
gene id: 1796616:A4V09_RS02825
uniprot id: A0A1C7I545
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1796616:A4V09 RS05790
gene id: 1796616:A4V09_RS05790
uniprot id: A0A1C7I6M2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1796616:A4V09 RS13655
gene id: 1796616:A4V09_RS13655
uniprot id: A0A1C7IES7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1796616:A4V09 RS20335
gene id: 1796616:A4V09_RS20335
uniprot id: A0A1C7IDV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1796616:A4V09 RS00065
gene id: 1796616:A4V09_RS00065
uniprot id: A0A1C7I3S6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS04555
gene id: 1796616:A4V09_RS04555
uniprot id: A0A1C7I821
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1796616:A4V09 RS14210
gene id: 1796616:A4V09_RS14210
uniprot id: A0A1C7IG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796616:A4V09 RS13395
gene id: 1796616:A4V09_RS13395
uniprot id: A0A1C7ICJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1796616:A4V09 RS13285
gene id: 1796616:A4V09_RS13285
uniprot id: A0A1C7ICQ7
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS00950
gene id: 1796616:A4V09_RS00950
uniprot id: A0A1C7IHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1796616:A4V09 RS05945
gene id: 1796616:A4V09_RS05945
uniprot id: A0A1C7I9W9
names: Similarity
messages: Belongs to the TrpF family.

1796616:A4V09 RS09305
gene id: 1796616:A4V09_RS09305
uniprot id: A0A1C7I8H7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1796616:A4V09 RS20155
gene id: 1796616:A4V09_RS20155
uniprot id: A0A1C7IDP5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1796616:A4V09 RS01580
gene id: 1796616:A4V09_RS01580
uniprot id: A0A1C7I8K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1796616:A4V09 RS11185
gene id: 1796616:A4V09_RS11185
uniprot id: A0A1C7IBE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1796616:A4V09 RS08035
gene id: 1796616:A4V09_RS08035
uniprot id: A0A1C7I9W1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS06050
gene id: 1796616:A4V09_RS06050
uniprot id: A0A1C7I6R9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1796616:A4V09 RS17730
gene id: 1796616:A4V09_RS17730
uniprot id: A0A1C7ICJ5
names: Similarity
messages: Belongs to the aldose epimerase family.

1796616:A4V09 RS02040
gene id: 1796616:A4V09_RS02040
uniprot id: A0A1C7I7U2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1796616:A4V09 RS03910
gene id: 1796616:A4V09_RS03910
uniprot id: A0A1C7I8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1796616:A4V09 RS08310
gene id: 1796616:A4V09_RS08310
uniprot id: A0A1C7IC03
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS17585
gene id: 1796616:A4V09_RS17585
uniprot id: A0A1C7IGR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1796616:A4V09 RS02850
gene id: 1796616:A4V09_RS02850
uniprot id: A0A1C7I7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1796616:A4V09 RS16405
gene id: 1796616:A4V09_RS16405
uniprot id: A0A1C7IIG8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1796616:A4V09 RS12260
gene id: 1796616:A4V09_RS12260
uniprot id: A0A1C7I9X7
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS21575
gene id: 1796616:A4V09_RS21575
uniprot id: A0A1C7IEN8
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1796616:A4V09 RS08055
gene id: 1796616:A4V09_RS08055
uniprot id: A0A1C7I9M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796616:A4V09 RS09205
gene id: 1796616:A4V09_RS09205
uniprot id: A0A1C7IBL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS12545
gene id: 1796616:A4V09_RS12545
uniprot id: A0A1C7IA27
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1796616:A4V09 RS16540
gene id: 1796616:A4V09_RS16540
uniprot id: A0A1C7IE27
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796616:A4V09 RS08910
gene id: 1796616:A4V09_RS08910
uniprot id: A0A1C7I8B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1796616:A4V09 RS08300
gene id: 1796616:A4V09_RS08300
uniprot id: A0A1C7I7X6
names: Similarity
messages: Belongs to the type A lantibiotic family.

1796616:A4V09 RS09295
gene id: 1796616:A4V09_RS09295
uniprot id: A0A1C7IAT0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1796616:A4V09 RS19365
gene id: 1796616:A4V09_RS19365
uniprot id: A0A1C7IDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS12280
gene id: 1796616:A4V09_RS12280
uniprot id: A0A1C7IKL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1796616:A4V09 RS03915
gene id: 1796616:A4V09_RS03915
uniprot id: A0A1C7I5P8
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1796616:A4V09 RS12530
gene id: 1796616:A4V09_RS12530
uniprot id: A0A1C7IBU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1796616:A4V09 RS10975
gene id: 1796616:A4V09_RS10975
uniprot id: A0A1C7ICI7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1796616:A4V09 RS09935
gene id: 1796616:A4V09_RS09935
uniprot id: A0A1C7IB27
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1796616:A4V09 RS03330
gene id: 1796616:A4V09_RS03330
uniprot id: A0A1C7I5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS02705
gene id: 1796616:A4V09_RS02705
uniprot id: A0A1C7I869
names: Similarity
messages: Belongs to the transpeptidase family.

1796616:A4V09 RS13175
gene id: 1796616:A4V09_RS13175
uniprot id: A0A1C7ICP0
names: Similarity
messages: Belongs to the RutC family.

1796616:A4V09 RS07090
gene id: 1796616:A4V09_RS07090
uniprot id: A0A1C7I942
names: Similarity
messages: Belongs to the peptidase S33 family.

1796616:A4V09 RS05245
gene id: 1796616:A4V09_RS05245
uniprot id: A0A1C7I6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1796616:A4V09 RS11985
gene id: 1796616:A4V09_RS11985
uniprot id: A0A1C7IDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS09945
gene id: 1796616:A4V09_RS09945
uniprot id: A0A1C7I8U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS10695
gene id: 1796616:A4V09_RS10695
uniprot id: A0A1C7I8Z4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS14685
gene id: 1796616:A4V09_RS14685
uniprot id: A0A1C7IB26
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS17110
gene id: 1796616:A4V09_RS17110
uniprot id: A0A1C7IEB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1796616:A4V09 RS10715
gene id: 1796616:A4V09_RS10715
uniprot id: A0A1C7IAX4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS21800
gene id: 1796616:A4V09_RS21800
uniprot id: A0A1C7IEF2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1796616:A4V09 RS15565
gene id: 1796616:A4V09_RS15565
uniprot id: A0A1C7IBI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1796616:A4V09 RS02760
gene id: 1796616:A4V09_RS02760
uniprot id: A0A1C7I6Y6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS20820
gene id: 1796616:A4V09_RS20820
uniprot id: A0A1C7IFU5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1796616:A4V09 RS12800
gene id: 1796616:A4V09_RS12800
uniprot id: A0A1C7IA32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS18170
gene id: 1796616:A4V09_RS18170
uniprot id: A0A1C7ICX8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1796616:A4V09 RS04150
gene id: 1796616:A4V09_RS04150
uniprot id: A0A1C7I7V6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1796616:A4V09 RS04940
gene id: 1796616:A4V09_RS04940
uniprot id: A0A1C7I817
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1796616:A4V09 RS14925
gene id: 1796616:A4V09_RS14925
uniprot id: A0A1C7ID15
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS07885
gene id: 1796616:A4V09_RS07885
uniprot id: A0A1C7I7R3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS14110
gene id: 1796616:A4V09_RS14110
uniprot id: A0A1C7IF04
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1796616:A4V09 RS13375
gene id: 1796616:A4V09_RS13375
uniprot id: A0A1C7IAD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

1796616:A4V09 RS15755
gene id: 1796616:A4V09_RS15755
uniprot id: A0A1C7IBT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1796616:A4V09 RS23495
gene id: 1796616:A4V09_RS23495
uniprot id: A0A1C7IFG5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS03840
gene id: 1796616:A4V09_RS03840
uniprot id: A0A1C7I7I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1796616:A4V09 RS19355
gene id: 1796616:A4V09_RS19355
uniprot id: A0A1C7IGU4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS01950
gene id: 1796616:A4V09_RS01950
uniprot id: A0A1C7I8R2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1796616:A4V09 RS01545
gene id: 1796616:A4V09_RS01545
uniprot id: A0A1C7I4R0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796616:A4V09 RS21590
gene id: 1796616:A4V09_RS21590
uniprot id: A0A1C7IG77
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1796616:A4V09 RS04960
gene id: 1796616:A4V09_RS04960
uniprot id: A0A1C7IA85
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1796616:A4V09 RS06555
gene id: 1796616:A4V09_RS06555
uniprot id: A0A1C7IA90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1796616:A4V09 RS03930
gene id: 1796616:A4V09_RS03930
uniprot id: A0A1C7I809
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1796616:A4V09 RS04790
gene id: 1796616:A4V09_RS04790
uniprot id: A0A1C7I860
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1796616:A4V09 RS20895
gene id: 1796616:A4V09_RS20895
uniprot id: A0A1C7IIH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS16050
gene id: 1796616:A4V09_RS16050
uniprot id: A0A1C7IDK7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS19315
gene id: 1796616:A4V09_RS19315
uniprot id: A0A1C7IDB7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1796616:A4V09 RS02935
gene id: 1796616:A4V09_RS02935
uniprot id: A0A1C7I717
names: Similarity
messages: Belongs to the citrate synthase family.

1796616:A4V09 RS21325
gene id: 1796616:A4V09_RS21325
uniprot id: A0A1C7IE97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS13500
gene id: 1796616:A4V09_RS13500
uniprot id: A0A1C7ICC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1796616:A4V09 RS13915
gene id: 1796616:A4V09_RS13915
uniprot id: A0A1C7IAM9
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS09870
gene id: 1796616:A4V09_RS09870
uniprot id: A0A1C7I8N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1796616:A4V09 RS13225
gene id: 1796616:A4V09_RS13225
uniprot id: A0A1C7IEJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1796616:A4V09 RS07425
gene id: 1796616:A4V09_RS07425
uniprot id: A0A1C7I7G2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

1796616:A4V09 RS07630
gene id: 1796616:A4V09_RS07630
uniprot id: A0A1C7IKF0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1796616:A4V09 RS10035
gene id: 1796616:A4V09_RS10035
uniprot id: A0A1C7I8V8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1796616:A4V09 RS23010
gene id: 1796616:A4V09_RS23010
uniprot id: A0A1C7IF69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1796616:A4V09 RS08535
gene id: 1796616:A4V09_RS08535
uniprot id: A0A1C7I819
names: Similarity
messages: Belongs to the aldose epimerase family.

1796616:A4V09 RS02585
gene id: 1796616:A4V09_RS02585
uniprot id: A0A1C7I4Y5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS22500
gene id: 1796616:A4V09_RS22500
uniprot id: A0A1C7IEU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS23315
gene id: 1796616:A4V09_RS23315
uniprot id: A0A1C7IH19
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1796616:A4V09 RS02080
gene id: 1796616:A4V09_RS02080
uniprot id: A0A1C7I4P3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS06665
gene id: 1796616:A4V09_RS06665
uniprot id: A0A1C7I770
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS08240
gene id: 1796616:A4V09_RS08240
uniprot id: A0A1C7IB49
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS23470
gene id: 1796616:A4V09_RS23470
uniprot id: A0A1C7IFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS08965
gene id: 1796616:A4V09_RS08965
uniprot id: A0A1C7I8D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1796616:A4V09 RS20365
gene id: 1796616:A4V09_RS20365
uniprot id: A0A1C7IDU0
names: Similarity
messages: Belongs to the glutamate synthase family.

1796616:A4V09 RS08955
gene id: 1796616:A4V09_RS08955
uniprot id: A0A1C7IBH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1796616:A4V09 RS08130
gene id: 1796616:A4V09_RS08130
uniprot id: A0A1C7I7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1796616:A4V09 RS23100
gene id: 1796616:A4V09_RS23100
uniprot id: A0A1C7IHG1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1796616:A4V09 RS15285
gene id: 1796616:A4V09_RS15285
uniprot id: A0A1C7IDP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1796616:A4V09 RS19325
gene id: 1796616:A4V09_RS19325
uniprot id: A0A1C7IFM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS08520
gene id: 1796616:A4V09_RS08520
uniprot id: A0A1C7II83
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS06085
gene id: 1796616:A4V09_RS06085
uniprot id: A0A1C7I6V4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS05150
gene id: 1796616:A4V09_RS05150
uniprot id: A0A1C7I8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1796616:A4V09 RS10305
gene id: 1796616:A4V09_RS10305
uniprot id: A0A1C7IB96
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1796616:A4V09 RS13305
gene id: 1796616:A4V09_RS13305
uniprot id: A0A1C7IAD8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1796616:A4V09 RS12620
gene id: 1796616:A4V09_RS12620
uniprot id: A0A1C7IA77
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1796616:A4V09 RS02750
gene id: 1796616:A4V09_RS02750
uniprot id: A0A1C7I578
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796616:A4V09 RS11820
gene id: 1796616:A4V09_RS11820
uniprot id: A0A1C7I9P8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS06165
gene id: 1796616:A4V09_RS06165
uniprot id: A0A1C7I6Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1796616:A4V09 RS16280
gene id: 1796616:A4V09_RS16280
uniprot id: A0A1C7IFB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1796616:A4V09 RS02395
gene id: 1796616:A4V09_RS02395
uniprot id: A0A1C7I6Z2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1796616:A4V09 RS20570
gene id: 1796616:A4V09_RS20570
uniprot id: A0A1C7IDZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1796616:A4V09 RS01565
gene id: 1796616:A4V09_RS01565
uniprot id: A0A1C7I7L6
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS11125
gene id: 1796616:A4V09_RS11125
uniprot id: A0A1C7IDF3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1796616:A4V09 RS19870
gene id: 1796616:A4V09_RS19870
uniprot id: A0A1C7IDI3
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1796616:A4V09 RS01270
gene id: 1796616:A4V09_RS01270
uniprot id: A0A1C7I7G5
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1796616:A4V09 RS11685
gene id: 1796616:A4V09_RS11685
uniprot id: A0A1C7IBE1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1796616:A4V09 RS17850
gene id: 1796616:A4V09_RS17850
uniprot id: A0A1C7IEE8
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS02925
gene id: 1796616:A4V09_RS02925
uniprot id: A0A1C7I5A5
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1796616:A4V09 RS17685
gene id: 1796616:A4V09_RS17685
uniprot id: A0A1C7ICG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS06310
gene id: 1796616:A4V09_RS06310
uniprot id: A0A1C7I8Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1796616:A4V09 RS16460
gene id: 1796616:A4V09_RS16460
uniprot id: A0A1C7IBW8
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS00265
gene id: 1796616:A4V09_RS00265
uniprot id: A0A1C7I5Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1796616:A4V09 RS10520
gene id: 1796616:A4V09_RS10520
uniprot id: A0A1C7ID49
names: Similarity
messages: Belongs to the thioredoxin family.

1796616:A4V09 RS15965
gene id: 1796616:A4V09_RS15965
uniprot id: A0A1C7IE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS11865
gene id: 1796616:A4V09_RS11865
uniprot id: A0A1C7I9L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1796616:A4V09 RS19425
gene id: 1796616:A4V09_RS19425
uniprot id: A0A1C7IHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1796616:A4V09 RS14580
gene id: 1796616:A4V09_RS14580
uniprot id: A0A1C7ICV6
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS09575
gene id: 1796616:A4V09_RS09575
uniprot id: A0A1C7I8M5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796616:A4V09 RS07505
gene id: 1796616:A4V09_RS07505
uniprot id: A0A1C7IBK3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS15850
gene id: 1796616:A4V09_RS15850
uniprot id: A0A1C7IDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS18005
gene id: 1796616:A4V09_RS18005
uniprot id: A0A1C7ICP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS04945
gene id: 1796616:A4V09_RS04945
uniprot id: A0A1C7I9D6
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS08295
gene id: 1796616:A4V09_RS08295
uniprot id: A0A1C7I7X6
names: Similarity
messages: Belongs to the type A lantibiotic family.

1796616:A4V09 RS23060
gene id: 1796616:A4V09_RS23060
uniprot id: A0A1C7IIA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1796616:A4V09 RS06925
gene id: 1796616:A4V09_RS06925
uniprot id: A0A1C7I911
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1796616:A4V09 RS18935
gene id: 1796616:A4V09_RS18935
uniprot id: A0A1C7ID27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796616:A4V09 RS10405
gene id: 1796616:A4V09_RS10405
uniprot id: A0A1C7I8X7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1796616:A4V09 RS02860
gene id: 1796616:A4V09_RS02860
uniprot id: A0A1C7I5E0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1796616:A4V09 RS07450
gene id: 1796616:A4V09_RS07450
uniprot id: A0A1C7I9V1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1796616:A4V09 RS02590
gene id: 1796616:A4V09_RS02590
uniprot id: A0A1C7I6V5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS06990
gene id: 1796616:A4V09_RS06990
uniprot id: A0A1C7I785
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm

1796616:A4V09 RS17510
gene id: 1796616:A4V09_RS17510
uniprot id: A0A1C7IFW2
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS03260
gene id: 1796616:A4V09_RS03260
uniprot id: A0A1C7I5H3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1796616:A4V09 RS16580
gene id: 1796616:A4V09_RS16580
uniprot id: A0A1C7IC23
names: Similarity
messages: Belongs to the arginase family.

1796616:A4V09 RS19240
gene id: 1796616:A4V09_RS19240
uniprot id: A0A1C7IF30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1796616:A4V09 RS05155
gene id: 1796616:A4V09_RS05155
uniprot id: A0A1C7I8C3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1796616:A4V09 RS11955
gene id: 1796616:A4V09_RS11955
uniprot id: A0A1C7I9N5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS07680
gene id: 1796616:A4V09_RS07680
uniprot id: A0A1C7IAT6
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1796616:A4V09 RS05235
gene id: 1796616:A4V09_RS05235
uniprot id: A0A1C7I9I6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1796616:A4V09 RS14525
gene id: 1796616:A4V09_RS14525
uniprot id: A0A1C7ICU6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1796616:A4V09 RS20955
gene id: 1796616:A4V09_RS20955
uniprot id: A0A1C7IGA2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS13060
gene id: 1796616:A4V09_RS13060
uniprot id: A0A1C7IA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20160
gene id: 1796616:A4V09_RS20160
uniprot id: A0A1C7IDR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1796616:A4V09 RS01905
gene id: 1796616:A4V09_RS01905
uniprot id: A0A1C7IFY3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1796616:A4V09 RS16385
gene id: 1796616:A4V09_RS16385
uniprot id: A0A1C7IDR2
names: Similarity
messages: Belongs to the peptidase C40 family.

1796616:A4V09 RS17175
gene id: 1796616:A4V09_RS17175
uniprot id: A0A1C7IEC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13055
gene id: 1796616:A4V09_RS13055
uniprot id: A0A1C7IAF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS14420
gene id: 1796616:A4V09_RS14420
uniprot id: A0A1C7ID99
names: Similarity
messages: Belongs to the peptidase S14 family.

1796616:A4V09 RS12390
gene id: 1796616:A4V09_RS12390
uniprot id: A0A1C7IE37
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796616:A4V09 RS03795
gene id: 1796616:A4V09_RS03795
uniprot id: A0A1C7I5M1
names: Similarity
messages: Belongs to the asp23 family.

1796616:A4V09 RS04730
gene id: 1796616:A4V09_RS04730
uniprot id: A0A1C7I8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1796616:A4V09 RS07650
gene id: 1796616:A4V09_RS07650
uniprot id: A0A1C7I9P1
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

1796616:A4V09 RS03560
gene id: 1796616:A4V09_RS03560
uniprot id: A0A1C7I5F9
names: Similarity
messages: Belongs to the fabD family.

1796616:A4V09 RS11190
gene id: 1796616:A4V09_RS11190
uniprot id: A0A1C7I9G0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1796616:A4V09 RS13130
gene id: 1796616:A4V09_RS13130
uniprot id: A0A1C7ICE7
names: Subcellular Location Annotation
messages: Cell membrane

1796616:A4V09 RS22985
gene id: 1796616:A4V09_RS22985
uniprot id: A0A1C7IHE5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS13885
gene id: 1796616:A4V09_RS13885
uniprot id: A0A1C7IEW5
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1796616:A4V09 RS01435
gene id: 1796616:A4V09_RS01435
uniprot id: A0A1C7I8H5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15910
gene id: 1796616:A4V09_RS15910
uniprot id: A0A1C7IDR5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1796616:A4V09 RS15035
gene id: 1796616:A4V09_RS15035
uniprot id: A0A1C7IB87
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS05840
gene id: 1796616:A4V09_RS05840
uniprot id: A0A1C7I6N2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1796616:A4V09 RS10780
gene id: 1796616:A4V09_RS10780
uniprot id: A0A1C7ICF7
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS23380
gene id: 1796616:A4V09_RS23380
uniprot id: A0A1C7IJ06
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS02615
gene id: 1796616:A4V09_RS02615
uniprot id: A0A1C7I937
names: Similarity
messages: Belongs to the carbamate kinase family.

1796616:A4V09 RS20725
gene id: 1796616:A4V09_RS20725
uniprot id: A0A1C7IHL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1796616:A4V09 RS06885
gene id: 1796616:A4V09_RS06885
uniprot id: A0A1C7I7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1796616:A4V09 RS20560
gene id: 1796616:A4V09_RS20560
uniprot id: A0A1C7IHI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS15310
gene id: 1796616:A4V09_RS15310
uniprot id: A0A1C7ID78
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS20680
gene id: 1796616:A4V09_RS20680
uniprot id: A0A1C7IE15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS05005
gene id: 1796616:A4V09_RS05005
uniprot id: A0A1C7I830
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1796616:A4V09 RS22280
gene id: 1796616:A4V09_RS22280
uniprot id: A0A1C7IH25
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1796616:A4V09 RS15240
gene id: 1796616:A4V09_RS15240
uniprot id: A0A1C7IBJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

1796616:A4V09 RS16650
gene id: 1796616:A4V09_RS16650
uniprot id: A0A1C7IGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1796616:A4V09 RS01780
gene id: 1796616:A4V09_RS01780
uniprot id: A0A1C7I4Q8
names: Similarity
messages: Belongs to the UPF0178 family.

1796616:A4V09 RS14985
gene id: 1796616:A4V09_RS14985
uniprot id: A0A1C7IB78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1796616:A4V09 RS15805
gene id: 1796616:A4V09_RS15805
uniprot id: A0A1C7IBU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1796616:A4V09 RS03385
gene id: 1796616:A4V09_RS03385
uniprot id: A0A1C7I8L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS03130
gene id: 1796616:A4V09_RS03130
uniprot id: A0A1C7IFN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1796616:A4V09 RS02690
gene id: 1796616:A4V09_RS02690
uniprot id: A0A1C7I506
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1796616:A4V09 RS13835
gene id: 1796616:A4V09_RS13835
uniprot id: A0A1C7ID01
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1796616:A4V09 RS20640
gene id: 1796616:A4V09_RS20640
uniprot id: A0A1C7IG99
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796616:A4V09 RS19780
gene id: 1796616:A4V09_RS19780
uniprot id: A0A1C7IGE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS03000
gene id: 1796616:A4V09_RS03000
uniprot id: A0A1C7I8C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1796616:A4V09 RS04950
gene id: 1796616:A4V09_RS04950
uniprot id: A0A1C7I669
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1796616:A4V09 RS02675
gene id: 1796616:A4V09_RS02675
uniprot id: A0A1C7I745
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1796616:A4V09 RS04895
gene id: 1796616:A4V09_RS04895
uniprot id: A0A1C7IA75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1796616:A4V09 RS16655
gene id: 1796616:A4V09_RS16655
uniprot id: A0A1C7IEC5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS11830
gene id: 1796616:A4V09_RS11830
uniprot id: A0A1C7IC00
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1796616:A4V09 RS13650
gene id: 1796616:A4V09_RS13650
uniprot id: A0A1C7IAL5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1796616:A4V09 RS19910
gene id: 1796616:A4V09_RS19910
uniprot id: A0A1C7IFR7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1796616:A4V09 RS00350
gene id: 1796616:A4V09_RS00350
uniprot id: A0A1C7I3X3
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1796616:A4V09 RS03165
gene id: 1796616:A4V09_RS03165
uniprot id: A0A1C7I769
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796616:A4V09 RS01060
gene id: 1796616:A4V09_RS01060
uniprot id: A0A1C7I4E0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS00125
gene id: 1796616:A4V09_RS00125
uniprot id: A0A1C7I977
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1796616:A4V09 RS21390
gene id: 1796616:A4V09_RS21390
uniprot id: A0A1C7IGM6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1796616:A4V09 RS06905
gene id: 1796616:A4V09_RS06905
uniprot id: A0A1C7I9A8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1796616:A4V09 RS02030
gene id: 1796616:A4V09_RS02030
uniprot id: A0A1C7I4N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20715
gene id: 1796616:A4V09_RS20715
uniprot id: A0A1C7IDZ5
names: Similarity
messages: Belongs to the IlvD/Edd family.

1796616:A4V09 RS04785
gene id: 1796616:A4V09_RS04785
uniprot id: A0A1C7I8F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1796616:A4V09 RS17405
gene id: 1796616:A4V09_RS17405
uniprot id: A0A1C7ICE5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1796616:A4V09 RS20845
gene id: 1796616:A4V09_RS20845
uniprot id: A0A1C7IGD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS19915
gene id: 1796616:A4V09_RS19915
uniprot id: A0A1C7IDU5
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1796616:A4V09 RS12250
gene id: 1796616:A4V09_RS12250
uniprot id: A0A1C7ID71
names: Similarity
messages: Belongs to the EamA transporter family.

1796616:A4V09 RS00970
gene id: 1796616:A4V09_RS00970
uniprot id: A0A1C7I4D0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1796616:A4V09 RS20535
gene id: 1796616:A4V09_RS20535
uniprot id: A0A1C7IDU3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1796616:A4V09 RS23510
gene id: 1796616:A4V09_RS23510
uniprot id: A0A1C7IHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS16380
gene id: 1796616:A4V09_RS16380
uniprot id: A0A1C7IBX3
names: Similarity
messages: Belongs to the peptidase C40 family.

1796616:A4V09 RS21545
gene id: 1796616:A4V09_RS21545
uniprot id: A0A1C7II16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1796616:A4V09 RS13390
gene id: 1796616:A4V09_RS13390
uniprot id: A0A1C7ICT0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1796616:A4V09 RS06960
gene id: 1796616:A4V09_RS06960
uniprot id: A0A1C7I7D8
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS05040
gene id: 1796616:A4V09_RS05040
uniprot id: A0A1C7I8J3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1796616:A4V09 RS05930
gene id: 1796616:A4V09_RS05930
uniprot id: A0A1C7I6L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1796616:A4V09 RS08960
gene id: 1796616:A4V09_RS08960
uniprot id: A0A1C7I880
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1796616:A4V09 RS17260
gene id: 1796616:A4V09_RS17260
uniprot id: A0A1C7IE39
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS04345
gene id: 1796616:A4V09_RS04345
uniprot id: A0A1C7I5W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS18385
gene id: 1796616:A4V09_RS18385
uniprot id: A0A1C7IF64
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1796616:A4V09 RS03585
gene id: 1796616:A4V09_RS03585
uniprot id: A0A1C7I9K3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1796616:A4V09 RS10510
gene id: 1796616:A4V09_RS10510
uniprot id: A0A1C7IFY1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1796616:A4V09 RS09410
gene id: 1796616:A4V09_RS09410
uniprot id: A0A1C7I8K4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1796616:A4V09 RS01910
gene id: 1796616:A4V09_RS01910
uniprot id: A0A1C7I4S9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1796616:A4V09 RS10885
gene id: 1796616:A4V09_RS10885
uniprot id: A0A1C7I964
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1796616:A4V09 RS17830
gene id: 1796616:A4V09_RS17830
uniprot id: A0A1C7IEN4
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS14810
gene id: 1796616:A4V09_RS14810
uniprot id: A0A1C7IB42
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS11225
gene id: 1796616:A4V09_RS11225
uniprot id: A0A1C7IDH4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1796616:A4V09 RS21755
gene id: 1796616:A4V09_RS21755
uniprot id: A0A1C7IEI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS02740
gene id: 1796616:A4V09_RS02740
uniprot id: A0A1C7I754
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1796616:A4V09 RS02340
gene id: 1796616:A4V09_RS02340
uniprot id: A0A1C7I6Y7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1796616:A4V09 RS08145
gene id: 1796616:A4V09_RS08145
uniprot id: A0A1C7I9Y1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1796616:A4V09 RS23900
gene id: 1796616:A4V09_RS23900
uniprot id: A0A1C7IHT2
names: Similarity
messages: Belongs to the HypE family.

1796616:A4V09 RS10025
gene id: 1796616:A4V09_RS10025
uniprot id: A0A1C7IC05
names: Similarity
messages: Belongs to the RecJ family.

1796616:A4V09 RS19525
gene id: 1796616:A4V09_RS19525
uniprot id: A0A1C7IDC9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1796616:A4V09 RS03700
gene id: 1796616:A4V09_RS03700
uniprot id: A0A1C7I7X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1796616:A4V09 RS03740
gene id: 1796616:A4V09_RS03740
uniprot id: A0A1C7I8S2
names: Subunit
messages: Homodimer.

1796616:A4V09 RS09830
gene id: 1796616:A4V09_RS09830
uniprot id: A0A1C7I8R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1796616:A4V09 RS01495
gene id: 1796616:A4V09_RS01495
uniprot id: A0A1C7I4P9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1796616:A4V09 RS23385
gene id: 1796616:A4V09_RS23385
uniprot id: A0A1C7IF95
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS10470
gene id: 1796616:A4V09_RS10470
uniprot id: A0A1C7IBC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

1796616:A4V09 RS04720
gene id: 1796616:A4V09_RS04720
uniprot id: A0A1C7I687
names: Similarity
messages: Belongs to the EamA transporter family.

1796616:A4V09 RS14555
gene id: 1796616:A4V09_RS14555
uniprot id: A0A1C7IDC5
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS13765
gene id: 1796616:A4V09_RS13765
uniprot id: A0A1C7IAN7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS12560
gene id: 1796616:A4V09_RS12560
uniprot id: A0A1C7IC44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS11240
gene id: 1796616:A4V09_RS11240
uniprot id: A0A1C7I9G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1796616:A4V09 RS20455
gene id: 1796616:A4V09_RS20455
uniprot id: A0A1C7II94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1796616:A4V09 RS09185
gene id: 1796616:A4V09_RS09185
uniprot id: A0A1C7I8C7
names: Subcellular Location Annotation
messages: Cytoplasm

1796616:A4V09 RS22920
gene id: 1796616:A4V09_RS22920
uniprot id: A0A1C7IF21
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796616:A4V09 RS03400
gene id: 1796616:A4V09_RS03400
uniprot id: A0A1C7I9I4
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1796616:A4V09 RS15605
gene id: 1796616:A4V09_RS15605
uniprot id: A0A1C7IBH9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS05175
gene id: 1796616:A4V09_RS05175
uniprot id: A0A1C7I854
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1796616:A4V09 RS23325
gene id: 1796616:A4V09_RS23325
uniprot id: A0A1C7IF86
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1796616:A4V09 RS15130
gene id: 1796616:A4V09_RS15130
uniprot id: A0A1C7IDE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796616:A4V09 RS16145
gene id: 1796616:A4V09_RS16145
uniprot id: A0A1C7IBR3
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS23475
gene id: 1796616:A4V09_RS23475
uniprot id: A0A1C7IH51
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1796616:A4V09 RS17210
gene id: 1796616:A4V09_RS17210
uniprot id: A0A1C7IFR1
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1796616:A4V09 RS22270
gene id: 1796616:A4V09_RS22270
uniprot id: A0A1C7IEU2
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1796616:A4V09 RS12090
gene id: 1796616:A4V09_RS12090
uniprot id: A0A1C7I9Q5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS19070
gene id: 1796616:A4V09_RS19070
uniprot id: A0A1C7IFI2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS06125
gene id: 1796616:A4V09_RS06125
uniprot id: A0A1C7I8W5
names: Similarity
messages: Belongs to the asp23 family.

1796616:A4V09 RS04080
gene id: 1796616:A4V09_RS04080
uniprot id: A0A1C7I5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1796616:A4V09 RS02310
gene id: 1796616:A4V09_RS02310
uniprot id: A0A1C7I4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1796616:A4V09 RS22875
gene id: 1796616:A4V09_RS22875
uniprot id: A0A1C7IF54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20920
gene id: 1796616:A4V09_RS20920
uniprot id: A0A1C7IE31
names: Similarity
messages: Belongs to the glutamate synthase family.

1796616:A4V09 RS11175
gene id: 1796616:A4V09_RS11175
uniprot id: A0A1C7IDG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS06955
gene id: 1796616:A4V09_RS06955
uniprot id: A0A1C7I9B6
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS15770
gene id: 1796616:A4V09_RS15770
uniprot id: A0A1C7IDG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1796616:A4V09 RS19345
gene id: 1796616:A4V09_RS19345
uniprot id: A0A1C7IF48
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1796616:A4V09 RS00290
gene id: 1796616:A4V09_RS00290
uniprot id: A0A1C7I5R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1796616:A4V09 RS17370
gene id: 1796616:A4V09_RS17370
uniprot id: A0A1C7ICJ9
names: Similarity
messages: Belongs to the GerABKA family.

1796616:A4V09 RS02460
gene id: 1796616:A4V09_RS02460
uniprot id: A0A1C7I570
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS13725
gene id: 1796616:A4V09_RS13725
uniprot id: A0A1C7ICY3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1796616:A4V09 RS03530
gene id: 1796616:A4V09_RS03530
uniprot id: A0A1C7IHY1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1796616:A4V09 RS17845
gene id: 1796616:A4V09_RS17845
uniprot id: A0A1C7ICL6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796616:A4V09 RS07140
gene id: 1796616:A4V09_RS07140
uniprot id: A0A1C7I793
names: Subcellular Location Annotation
messages: Membrane

1796616:A4V09 RS05065
gene id: 1796616:A4V09_RS05065
uniprot id: A0A1C7I840
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1796616:A4V09 RS09375
gene id: 1796616:A4V09_RS09375
uniprot id: A0A1C7IAA3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1796616:A4V09 RS20645
gene id: 1796616:A4V09_RS20645
uniprot id: A0A1C7IG49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS04390
gene id: 1796616:A4V09_RS04390
uniprot id: A0A1C7I5T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1796616:A4V09 RS19020
gene id: 1796616:A4V09_RS19020
uniprot id: A0A1C7I977
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1796616:A4V09 RS01785
gene id: 1796616:A4V09_RS01785
uniprot id: A0A1C7I4J3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS19770
gene id: 1796616:A4V09_RS19770
uniprot id: A0A1C7IHX3
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1796616:A4V09 RS21280
gene id: 1796616:A4V09_RS21280
uniprot id: A0A1C7IIQ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS17220
gene id: 1796616:A4V09_RS17220
uniprot id: A0A1C7ICB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1796616:A4V09 RS01370
gene id: 1796616:A4V09_RS01370
uniprot id: A0A1C7I6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1796616:A4V09 RS21580
gene id: 1796616:A4V09_RS21580
uniprot id: A0A1C7IEC0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1796616:A4V09 RS19375
gene id: 1796616:A4V09_RS19375
uniprot id: A0A1C7IHQ3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS13160
gene id: 1796616:A4V09_RS13160
uniprot id: A0A1C7IA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS01500
gene id: 1796616:A4V09_RS01500
uniprot id: A0A1C7I4L2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1796616:A4V09 RS13605
gene id: 1796616:A4V09_RS13605
uniprot id: A0A1C7ICW2
names: Similarity
messages: Belongs to the MecA family.

1796616:A4V09 RS05530
gene id: 1796616:A4V09_RS05530
uniprot id: A0A1C7IAI3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1796616:A4V09 RS03615
gene id: 1796616:A4V09_RS03615
uniprot id: A0A1C7I7E7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS16000
gene id: 1796616:A4V09_RS16000
uniprot id: A0A1C7IF56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS23230
gene id: 1796616:A4V09_RS23230
uniprot id: A0A1C7IHF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1796616:A4V09 RS09990
gene id: 1796616:A4V09_RS09990
uniprot id: A0A1C7ICU7
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1796616:A4V09 RS12535
gene id: 1796616:A4V09_RS12535
uniprot id: A0A1C7IDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS18240
gene id: 1796616:A4V09_RS18240
uniprot id: A0A1C7ICS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20040
gene id: 1796616:A4V09_RS20040
uniprot id: A0A1C7IH66
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1796616:A4V09 RS02155
gene id: 1796616:A4V09_RS02155
uniprot id: A0A1C7I4Y7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1796616:A4V09 RS10255
gene id: 1796616:A4V09_RS10255
uniprot id: A0A1C7IAZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1796616:A4V09 RS11655
gene id: 1796616:A4V09_RS11655
uniprot id: A0A1C7IDR0
names: Similarity
messages: Belongs to the CapA family.

1796616:A4V09 RS14920
gene id: 1796616:A4V09_RS14920
uniprot id: A0A1C7IB63
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796616:A4V09 RS03310
gene id: 1796616:A4V09_RS03310
uniprot id: A0A1C7I5B9
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1796616:A4V09 RS06970
gene id: 1796616:A4V09_RS06970
uniprot id: A0A1C7I763
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1796616:A4V09 RS00435
gene id: 1796616:A4V09_RS00435
uniprot id: A0A1C7I6A3
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1796616:A4V09 RS13190
gene id: 1796616:A4V09_RS13190
uniprot id: A0A1C7IAA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1796616:A4V09 RS19800
gene id: 1796616:A4V09_RS19800
uniprot id: A0A1C7IDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1796616:A4V09 RS20180
gene id: 1796616:A4V09_RS20180
uniprot id: A0A1C7IG07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796616:A4V09 RS12925
gene id: 1796616:A4V09_RS12925
uniprot id: A0A1C7IA99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1796616:A4V09 RS02180
gene id: 1796616:A4V09_RS02180
uniprot id: A0A1C7I4X8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1796616:A4V09 RS09035
gene id: 1796616:A4V09_RS09035
uniprot id: A0A1C7IAP0
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

1796616:A4V09 RS03990
gene id: 1796616:A4V09_RS03990
uniprot id: A0A1C7I7S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1796616:A4V09 RS12790
gene id: 1796616:A4V09_RS12790
uniprot id: A0A1C7IBZ7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1796616:A4V09 RS15980
gene id: 1796616:A4V09_RS15980
uniprot id: A0A1C7IBX9
names: Similarity
messages: Belongs to the peptidase M17 family.

1796616:A4V09 RS17215
gene id: 1796616:A4V09_RS17215
uniprot id: A0A1C7IC83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1796616:A4V09 RS11925
gene id: 1796616:A4V09_RS11925
uniprot id: A0A1C7IHW0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1796616:A4V09 RS03705
gene id: 1796616:A4V09_RS03705
uniprot id: A0A1C7I7M6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1796616:A4V09 RS05740
gene id: 1796616:A4V09_RS05740
uniprot id: A0A1C7I6R1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1796616:A4V09 RS17455
gene id: 1796616:A4V09_RS17455
uniprot id: A0A1C7ICC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane