1796613:A4V03 RS13795
gene id: 1796613:A4V03_RS13795
uniprot id: A0A1C7H4H3
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS09105
gene id: 1796613:A4V03_RS09105
uniprot id: A0A1C7GYH2
names: Similarity
messages: Belongs to the fabD family.

1796613:A4V03 RS10065
gene id: 1796613:A4V03_RS10065
uniprot id: A0A1C7GZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796613:A4V03 RS11950
gene id: 1796613:A4V03_RS11950
uniprot id: A0A1C7H2F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1796613:A4V03 RS16620
gene id: 1796613:A4V03_RS16620
uniprot id: A0A1C7H5S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1796613:A4V03 RS17390
gene id: 1796613:A4V03_RS17390
uniprot id: A0A1C7H662
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1796613:A4V03 RS06895
gene id: 1796613:A4V03_RS06895
uniprot id: A0A1C7GY50
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1796613:A4V03 RS13980
gene id: 1796613:A4V03_RS13980
uniprot id: A0A1C7H1R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS11610
gene id: 1796613:A4V03_RS11610
uniprot id: A0A1C7GZQ8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1796613:A4V03 RS02930
gene id: 1796613:A4V03_RS02930
uniprot id: A0A1C7GZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1796613:A4V03 RS01925
gene id: 1796613:A4V03_RS01925
uniprot id: A0A1C7GY62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1796613:A4V03 RS09940
gene id: 1796613:A4V03_RS09940
uniprot id: A0A1C7GZM7
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS00040
gene id: 1796613:A4V03_RS00040
uniprot id: A0A1C7GWJ2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1796613:A4V03 RS17375
gene id: 1796613:A4V03_RS17375
uniprot id: A0A1C7H390
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS00160
gene id: 1796613:A4V03_RS00160
uniprot id: A0A1C7GVC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS19885
gene id: 1796613:A4V03_RS19885
uniprot id: A0A1C7H811
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1796613:A4V03 RS09085
gene id: 1796613:A4V03_RS09085
uniprot id: A0A1C7GZ58
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1796613:A4V03 RS17950
gene id: 1796613:A4V03_RS17950
uniprot id: A0A1C7H3D9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS09745
gene id: 1796613:A4V03_RS09745
uniprot id: A0A1C7H1U1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS09020
gene id: 1796613:A4V03_RS09020
uniprot id: A0A1C7H0V4
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS06100
gene id: 1796613:A4V03_RS06100
uniprot id: A0A1C7H0V9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1796613:A4V03 RS18015
gene id: 1796613:A4V03_RS18015
uniprot id: A0A1C7H3F9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS18850
gene id: 1796613:A4V03_RS18850
uniprot id: A0A1C7H5Q1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1796613:A4V03 RS09755
gene id: 1796613:A4V03_RS09755
uniprot id: A0A1C7GZH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1796613:A4V03 RS16885
gene id: 1796613:A4V03_RS16885
uniprot id: A0A1C7H4S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1796613:A4V03 RS13325
gene id: 1796613:A4V03_RS13325
uniprot id: A0A1C7H1D2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1796613:A4V03 RS01550
gene id: 1796613:A4V03_RS01550
uniprot id: A0A1C7GVU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS10310
gene id: 1796613:A4V03_RS10310
uniprot id: A0A1C7H1M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1796613:A4V03 RS01150
gene id: 1796613:A4V03_RS01150
uniprot id: A0A1C7GVI1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1796613:A4V03 RS15835
gene id: 1796613:A4V03_RS15835
uniprot id: A0A1C7H2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS18295
gene id: 1796613:A4V03_RS18295
uniprot id: A0A1C7H3Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1796613:A4V03 RS13190
gene id: 1796613:A4V03_RS13190
uniprot id: A0A1C7H464
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1796613:A4V03 RS01445
gene id: 1796613:A4V03_RS01445
uniprot id: A0A1C7GVN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1796613:A4V03 RS15185
gene id: 1796613:A4V03_RS15185
uniprot id: A0A1C7H293
names: Similarity
messages: Belongs to the peptidase S49 family.

1796613:A4V03 RS15875
gene id: 1796613:A4V03_RS15875
uniprot id: A0A1C7H5H7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1796613:A4V03 RS11405
gene id: 1796613:A4V03_RS11405
uniprot id: A0A1C7H7N3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1796613:A4V03 RS04420
gene id: 1796613:A4V03_RS04420
uniprot id: A0A1C7GYP6
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1796613:A4V03 RS17865
gene id: 1796613:A4V03_RS17865
uniprot id: A0A1C7H5Q2
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS06795
gene id: 1796613:A4V03_RS06795
uniprot id: A0A1C7GY52
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1796613:A4V03 RS18620
gene id: 1796613:A4V03_RS18620
uniprot id: A0A1C7H5U9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS07190
gene id: 1796613:A4V03_RS07190
uniprot id: A0A1V0QDJ8
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS19610
gene id: 1796613:A4V03_RS19610
uniprot id: A0A1C7H477
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS11070
gene id: 1796613:A4V03_RS11070
uniprot id: A0A1C7H367
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796613:A4V03 RS17890
gene id: 1796613:A4V03_RS17890
uniprot id: A0A1C7H5S9
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1796613:A4V03 RS01965
gene id: 1796613:A4V03_RS01965
uniprot id: A0A1C7GXN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1796613:A4V03 RS02325
gene id: 1796613:A4V03_RS02325
uniprot id: A0A1C7GXV7
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS14535
gene id: 1796613:A4V03_RS14535
uniprot id: A0A1C7H1S1
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS15040
gene id: 1796613:A4V03_RS15040
uniprot id: A0A1C7H1Z9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS08895
gene id: 1796613:A4V03_RS08895
uniprot id: A0A1C7H0T7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1796613:A4V03 RS10815
gene id: 1796613:A4V03_RS10815
uniprot id: A0A1C7H061
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS06005
gene id: 1796613:A4V03_RS06005
uniprot id: A0A1C7H010
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS18450
gene id: 1796613:A4V03_RS18450
uniprot id: A0A1C7H5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS00175
gene id: 1796613:A4V03_RS00175
uniprot id: A0A1C7H6I0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS00005
gene id: 1796613:A4V03_RS00005
uniprot id: A0A1C7GV97
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1796613:A4V03 RS14015
gene id: 1796613:A4V03_RS14015
uniprot id: A0A1C7H1I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS08720
gene id: 1796613:A4V03_RS08720
uniprot id: A0A1C7H1E2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1796613:A4V03 RS01470
gene id: 1796613:A4V03_RS01470
uniprot id: A0A1C7GXV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1796613:A4V03 RS03425
gene id: 1796613:A4V03_RS03425
uniprot id: A0A1C7H771
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1796613:A4V03 RS14255
gene id: 1796613:A4V03_RS14255
uniprot id: A0A1C7H3Y5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS07260
gene id: 1796613:A4V03_RS07260
uniprot id: A0A1C7GYL4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796613:A4V03 RS08220
gene id: 1796613:A4V03_RS08220
uniprot id: A0A1C7H1V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1796613:A4V03 RS02710
gene id: 1796613:A4V03_RS02710
uniprot id: A0A1C7GZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1796613:A4V03 RS14140
gene id: 1796613:A4V03_RS14140
uniprot id: A0A1C7H741
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1796613:A4V03 RS02965
gene id: 1796613:A4V03_RS02965
uniprot id: A0A1C7GWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1796613:A4V03 RS10085
gene id: 1796613:A4V03_RS10085
uniprot id: A0A1C7GZL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796613:A4V03 RS19060
gene id: 1796613:A4V03_RS19060
uniprot id: A0A1C7H624
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1796613:A4V03 RS17940
gene id: 1796613:A4V03_RS17940
uniprot id: A0A1C7H338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS15140
gene id: 1796613:A4V03_RS15140
uniprot id: A0A1C7H4H9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS00420
gene id: 1796613:A4V03_RS00420
uniprot id: A0A1C7GVA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1796613:A4V03 RS04430
gene id: 1796613:A4V03_RS04430
uniprot id: A0A1C7GX50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1796613:A4V03 RS02120
gene id: 1796613:A4V03_RS02120
uniprot id: A0A1C7H4Q9
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

1796613:A4V03 RS18500
gene id: 1796613:A4V03_RS18500
uniprot id: A0A1C7H5T2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1796613:A4V03 RS10250
gene id: 1796613:A4V03_RS10250
uniprot id: A0A1C7GZR8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796613:A4V03 RS03080
gene id: 1796613:A4V03_RS03080
uniprot id: A0A1C7GY80
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1796613:A4V03 RS11150
gene id: 1796613:A4V03_RS11150
uniprot id: A0A1C7H2F3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1796613:A4V03 RS06910
gene id: 1796613:A4V03_RS06910
uniprot id: A0A1C7GZZ2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1796613:A4V03 RS11845
gene id: 1796613:A4V03_RS11845
uniprot id: A0A1C7GZU5
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS01440
gene id: 1796613:A4V03_RS01440
uniprot id: A0A1C7GVM3
names: Similarity
messages: Belongs to the peptidase S8 family.

1796613:A4V03 RS06545
gene id: 1796613:A4V03_RS06545
uniprot id: A0A1C7GYA5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS14215
gene id: 1796613:A4V03_RS14215
uniprot id: A0A1C7H403
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1796613:A4V03 RS16870
gene id: 1796613:A4V03_RS16870
uniprot id: A0A1C7H312
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1796613:A4V03 RS12435
gene id: 1796613:A4V03_RS12435
uniprot id: A0A1C7H334
names: Similarity
messages: Belongs to the Skp family.

1796613:A4V03 RS04480
gene id: 1796613:A4V03_RS04480
uniprot id: A0A1C7GZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1796613:A4V03 RS10555
gene id: 1796613:A4V03_RS10555
uniprot id: A0A1C7H5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS03195
gene id: 1796613:A4V03_RS03195
uniprot id: A0A1C7GWS5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1796613:A4V03 RS14985
gene id: 1796613:A4V03_RS14985
uniprot id: A0A1C7H542
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1796613:A4V03 RS16140
gene id: 1796613:A4V03_RS16140
uniprot id: A0A1C7H4R7
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS00090
gene id: 1796613:A4V03_RS00090
uniprot id: A0A1C7GWJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1796613:A4V03 RS14025
gene id: 1796613:A4V03_RS14025
uniprot id: A0A1C7H4N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1796613:A4V03 RS09065
gene id: 1796613:A4V03_RS09065
uniprot id: A0A1C7H1J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1796613:A4V03 RS06465
gene id: 1796613:A4V03_RS06465
uniprot id: A0A1C7GXY7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1796613:A4V03 RS14055
gene id: 1796613:A4V03_RS14055
uniprot id: A0A1C7H1F9
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1796613:A4V03 RS01160
gene id: 1796613:A4V03_RS01160
uniprot id: A0A1C7GYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1796613:A4V03 RS12130
gene id: 1796613:A4V03_RS12130
uniprot id: A0A1C7H2J2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1796613:A4V03 RS19855
gene id: 1796613:A4V03_RS19855
uniprot id: A0A1C7H3I9
names: Similarity
messages: Belongs to the UPF0145 family.

1796613:A4V03 RS02785
gene id: 1796613:A4V03_RS02785
uniprot id: A0A1C7GXT4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1796613:A4V03 RS20245
gene id: 1796613:A4V03_RS20245
uniprot id: A0A1C7H4I5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS01785
gene id: 1796613:A4V03_RS01785
uniprot id: A0A7T8WTX9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1796613:A4V03 RS03375
gene id: 1796613:A4V03_RS03375
uniprot id: A0A1C7GYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1796613:A4V03 RS01510
gene id: 1796613:A4V03_RS01510
uniprot id: A0A1C7H777
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796613:A4V03 RS16905
gene id: 1796613:A4V03_RS16905
uniprot id: A0A1C7H311
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1796613:A4V03 RS16675
gene id: 1796613:A4V03_RS16675
uniprot id: A0A1C7H5T6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1796613:A4V03 RS19795
gene id: 1796613:A4V03_RS19795
uniprot id: A0A1C7H7F3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS14830
gene id: 1796613:A4V03_RS14830
uniprot id: A0A1C7H5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS17140
gene id: 1796613:A4V03_RS17140
uniprot id: A0A1C7H5D1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS06090
gene id: 1796613:A4V03_RS06090
uniprot id: A0A1C7GXT3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1796613:A4V03 RS03010
gene id: 1796613:A4V03_RS03010
uniprot id: A0A1C7GYK2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1796613:A4V03 RS10360
gene id: 1796613:A4V03_RS10360
uniprot id: A0A1C7GZZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1796613:A4V03 RS14370
gene id: 1796613:A4V03_RS14370
uniprot id: A0A1C7H408
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1796613:A4V03 RS13880
gene id: 1796613:A4V03_RS13880
uniprot id: A0A1C7H3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1796613:A4V03 RS10525
gene id: 1796613:A4V03_RS10525
uniprot id: A0A1C7H295
names: Similarity
messages: Belongs to the asparaginase 1 family.

1796613:A4V03 RS18490
gene id: 1796613:A4V03_RS18490
uniprot id: A0A1C7H629
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS17315
gene id: 1796613:A4V03_RS17315
uniprot id: A0A1C7H2R3
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1796613:A4V03 RS19475
gene id: 1796613:A4V03_RS19475
uniprot id: A0A1C7H6Q6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS00555
gene id: 1796613:A4V03_RS00555
uniprot id: A0A1C7H7R8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1796613:A4V03 RS12040
gene id: 1796613:A4V03_RS12040
uniprot id: A0A1C7H2W7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796613:A4V03 RS04815
gene id: 1796613:A4V03_RS04815
uniprot id: A0A1C7GXA5
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS11675
gene id: 1796613:A4V03_RS11675
uniprot id: A0A1C7H0M6
names: Similarity
messages: Belongs to the DapA family.

1796613:A4V03 RS12660
gene id: 1796613:A4V03_RS12660
uniprot id: A0A1C7H2T5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1796613:A4V03 RS10570
gene id: 1796613:A4V03_RS10570
uniprot id: A0A1C7GZ92
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1796613:A4V03 RS10550
gene id: 1796613:A4V03_RS10550
uniprot id: A0A1C7GZY0
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS01070
gene id: 1796613:A4V03_RS01070
uniprot id: A0A1C7GVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1796613:A4V03 RS16010
gene id: 1796613:A4V03_RS16010
uniprot id: A0A1C7H2N5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1796613:A4V03 RS17910
gene id: 1796613:A4V03_RS17910
uniprot id: A0A1C7H6D8
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1796613:A4V03 RS02975
gene id: 1796613:A4V03_RS02975
uniprot id: A0A1C7GY56
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS00395
gene id: 1796613:A4V03_RS00395
uniprot id: A0A1C7GVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1796613:A4V03 RS06405
gene id: 1796613:A4V03_RS06405
uniprot id: A0A1C7H052
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1796613:A4V03 RS03300
gene id: 1796613:A4V03_RS03300
uniprot id: A0A1C7GVX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1796613:A4V03 RS17245
gene id: 1796613:A4V03_RS17245
uniprot id: A0A1C7H372
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1796613:A4V03 RS20015
gene id: 1796613:A4V03_RS20015
uniprot id: A0A1C7H5I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS14405
gene id: 1796613:A4V03_RS14405
uniprot id: A0A1C7H7U3
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS06575
gene id: 1796613:A4V03_RS06575
uniprot id: A0A1C7GY28
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1796613:A4V03 RS09415
gene id: 1796613:A4V03_RS09415
uniprot id: A0A1C7H1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1796613:A4V03 RS07470
gene id: 1796613:A4V03_RS07470
uniprot id: A0A1C7GYH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1796613:A4V03 RS00525
gene id: 1796613:A4V03_RS00525
uniprot id: A0A1C7GXE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1796613:A4V03 RS07180
gene id: 1796613:A4V03_RS07180
uniprot id: A0A1C7GYC1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1796613:A4V03 RS07280
gene id: 1796613:A4V03_RS07280
uniprot id: A0A1C7H0I7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1796613:A4V03 RS01870
gene id: 1796613:A4V03_RS01870
uniprot id: A0A1C7H515
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1796613:A4V03 RS04285
gene id: 1796613:A4V03_RS04285
uniprot id: A0A1C7GX85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1796613:A4V03 RS06745
gene id: 1796613:A4V03_RS06745
uniprot id: A0A1C7GZW6
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1796613:A4V03 RS19910
gene id: 1796613:A4V03_RS19910
uniprot id: A0A1C7H7H2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Fimbrium
messages: Membrane

1796613:A4V03 RS19055
gene id: 1796613:A4V03_RS19055
uniprot id: A0A1C7H642
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1796613:A4V03 RS08375
gene id: 1796613:A4V03_RS08375
uniprot id: A0A1C7H7J2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS02025
gene id: 1796613:A4V03_RS02025
uniprot id: A0A1C7GXN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796613:A4V03 RS04600
gene id: 1796613:A4V03_RS04600
uniprot id: A0A1C7GZC7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1796613:A4V03 RS18155
gene id: 1796613:A4V03_RS18155
uniprot id: A0A1C7H5W5
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS02210
gene id: 1796613:A4V03_RS02210
uniprot id: A0A1C7GW16
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS10635
gene id: 1796613:A4V03_RS10635
uniprot id: A0A1C7GZA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1796613:A4V03 RS16575
gene id: 1796613:A4V03_RS16575
uniprot id: A0A1C7H2W1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1796613:A4V03 RS11835
gene id: 1796613:A4V03_RS11835
uniprot id: A0A1C7H8A5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796613:A4V03 RS17110
gene id: 1796613:A4V03_RS17110
uniprot id: A0A1C7H2Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1796613:A4V03 RS06930
gene id: 1796613:A4V03_RS06930
uniprot id: A0A1C7H6S8
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1796613:A4V03 RS16665
gene id: 1796613:A4V03_RS16665
uniprot id: A0A1C7H4L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1796613:A4V03 RS02585
gene id: 1796613:A4V03_RS02585
uniprot id: A0A1C7GY05
names: Similarity
messages: Belongs to the AIR synthase family.

1796613:A4V03 RS19760
gene id: 1796613:A4V03_RS19760
uniprot id: A0A1C7H6F8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1796613:A4V03 RS06830
gene id: 1796613:A4V03_RS06830
uniprot id: A0A1C7H0C3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1796613:A4V03 RS07390
gene id: 1796613:A4V03_RS07390
uniprot id: A0A1C7GXT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1796613:A4V03 RS06735
gene id: 1796613:A4V03_RS06735
uniprot id: A0A1C7GY25
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1796613:A4V03 RS01985
gene id: 1796613:A4V03_RS01985
uniprot id: A0A3A9BZJ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1796613:A4V03 RS08630
gene id: 1796613:A4V03_RS08630
uniprot id: A0A1C7H5D7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1796613:A4V03 RS16055
gene id: 1796613:A4V03_RS16055
uniprot id: A0A1C7H5K6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1796613:A4V03 RS06940
gene id: 1796613:A4V03_RS06940
uniprot id: A0A1C7H0K1
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS05720
gene id: 1796613:A4V03_RS05720
uniprot id: A0A1C7GZV8
names: Similarity
messages: Belongs to the isochorismate synthase family.

1796613:A4V03 RS02560
gene id: 1796613:A4V03_RS02560
uniprot id: A0A1C7GXP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1796613:A4V03 RS10060
gene id: 1796613:A4V03_RS10060
uniprot id: A0A1C7GYZ5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1796613:A4V03 RS18200
gene id: 1796613:A4V03_RS18200
uniprot id: A0A1C7H3R4
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS15430
gene id: 1796613:A4V03_RS15430
uniprot id: A0A1C7H270
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS13315
gene id: 1796613:A4V03_RS13315
uniprot id: A0A1C7H3K3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1796613:A4V03 RS18495
gene id: 1796613:A4V03_RS18495
uniprot id: A0A1C7H5U7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1796613:A4V03 RS02725
gene id: 1796613:A4V03_RS02725
uniprot id: A0A1C7GYI9
names: Similarity
messages: Belongs to the peptidase S41A family.

1796613:A4V03 RS15420
gene id: 1796613:A4V03_RS15420
uniprot id: A0A1C7H217
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1796613:A4V03 RS20220
gene id: 1796613:A4V03_RS20220
uniprot id: A0A1C7H844
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796613:A4V03 RS16730
gene id: 1796613:A4V03_RS16730
uniprot id: A0A1C7H1Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1796613:A4V03 RS16770
gene id: 1796613:A4V03_RS16770
uniprot id: A0A1C7H4P3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1796613:A4V03 RS16390
gene id: 1796613:A4V03_RS16390
uniprot id: A0A1C7H4U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1796613:A4V03 RS19845
gene id: 1796613:A4V03_RS19845
uniprot id: A0A1C7H677
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1796613:A4V03 RS16590
gene id: 1796613:A4V03_RS16590
uniprot id: A0A1C7H4X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1796613:A4V03 RS00900
gene id: 1796613:A4V03_RS00900
uniprot id: A0A1C7GVE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1796613:A4V03 RS01580
gene id: 1796613:A4V03_RS01580
uniprot id: A0A1C7GW08
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1796613:A4V03 RS03265
gene id: 1796613:A4V03_RS03265
uniprot id: A0A1C7GWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1796613:A4V03 RS14060
gene id: 1796613:A4V03_RS14060
uniprot id: A0A1C7H1Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS19030
gene id: 1796613:A4V03_RS19030
uniprot id: A0A1C7H5T0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1796613:A4V03 RS01915
gene id: 1796613:A4V03_RS01915
uniprot id: A0A1C7GV91
names: Similarity
messages: Belongs to the ParB family.

1796613:A4V03 RS03185
gene id: 1796613:A4V03_RS03185
uniprot id: A0A1C7GZE5
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS12650
gene id: 1796613:A4V03_RS12650
uniprot id: A0A1C7H140
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1796613:A4V03 RS14900
gene id: 1796613:A4V03_RS14900
uniprot id: A0A1C7H530
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS19075
gene id: 1796613:A4V03_RS19075
uniprot id: A0A1C7H3Y0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS16015
gene id: 1796613:A4V03_RS16015
uniprot id: A0A1C7H4W3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1796613:A4V03 RS03050
gene id: 1796613:A4V03_RS03050
uniprot id: A0A1C7GYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS04445
gene id: 1796613:A4V03_RS04445
uniprot id: A0A1C7GYW3
names: Similarity
messages: Belongs to the HSP15 family.

1796613:A4V03 RS12830
gene id: 1796613:A4V03_RS12830
uniprot id: A0A1C7H2W5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1796613:A4V03 RS01240
gene id: 1796613:A4V03_RS01240
uniprot id: A0A1C7GVN8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1796613:A4V03 RS03510
gene id: 1796613:A4V03_RS03510
uniprot id: A0A1C7GWR0
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS11375
gene id: 1796613:A4V03_RS11375
uniprot id: A0A1C7H2J7
names: Similarity
messages: Belongs to the aspartokinase family.

1796613:A4V03 RS01435
gene id: 1796613:A4V03_RS01435
uniprot id: A0A1C7GVR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS17360
gene id: 1796613:A4V03_RS17360
uniprot id: A0A1C7H5A5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1796613:A4V03 RS00745
gene id: 1796613:A4V03_RS00745
uniprot id: A0A1C7GUQ6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1796613:A4V03 RS18175
gene id: 1796613:A4V03_RS18175
uniprot id: A0A1C7H3N3
names: Similarity
messages: Belongs to the peptidase S41A family.

1796613:A4V03 RS19335
gene id: 1796613:A4V03_RS19335
uniprot id: A0A1C7H675
names: Function
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.
messages: Broad-specificity glycosaminoglycan lyase.

1796613:A4V03 RS13335
gene id: 1796613:A4V03_RS13335
uniprot id: A0A1C7H343
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1796613:A4V03 RS19225
gene id: 1796613:A4V03_RS19225
uniprot id: A0A1C7H456
names: Similarity
messages: Belongs to the peptidase M16 family.

1796613:A4V03 RS02265
gene id: 1796613:A4V03_RS02265
uniprot id: A0A1C7GW25
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1796613:A4V03 RS16595
gene id: 1796613:A4V03_RS16595
uniprot id: A0A1C7H2E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1796613:A4V03 RS07265
gene id: 1796613:A4V03_RS07265
uniprot id: A0A1C7H0P7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1796613:A4V03 RS19955
gene id: 1796613:A4V03_RS19955
uniprot id: A0A1C7H4I4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1796613:A4V03 RS14430
gene id: 1796613:A4V03_RS14430
uniprot id: A0A1C7H417
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1796613:A4V03 RS17980
gene id: 1796613:A4V03_RS17980
uniprot id: A0A1C7H3M0
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS05885
gene id: 1796613:A4V03_RS05885
uniprot id: A0A1C7GXY4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1796613:A4V03 RS05940
gene id: 1796613:A4V03_RS05940
uniprot id: A0A1C7H0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1796613:A4V03 RS14045
gene id: 1796613:A4V03_RS14045
uniprot id: A0A1C7H3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796613:A4V03 RS14160
gene id: 1796613:A4V03_RS14160
uniprot id: A0A1C7H3J7
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1796613:A4V03 RS13635
gene id: 1796613:A4V03_RS13635
uniprot id: A0A1C7H1K9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS00505
gene id: 1796613:A4V03_RS00505
uniprot id: A0A1C7H4Z6
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS00610
gene id: 1796613:A4V03_RS00610
uniprot id: A0A1C7GV95
names: Similarity
messages: Belongs to the UPF0758 family.

1796613:A4V03 RS13835
gene id: 1796613:A4V03_RS13835
uniprot id: A0A1C7H1B7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1796613:A4V03 RS19085
gene id: 1796613:A4V03_RS19085
uniprot id: A0A1C7H6Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1796613:A4V03 RS13205
gene id: 1796613:A4V03_RS13205
uniprot id: A0A1C7H3G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1796613:A4V03 RS12655
gene id: 1796613:A4V03_RS12655
uniprot id: A0A1C7H369
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS15905
gene id: 1796613:A4V03_RS15905
uniprot id: A0A1C7H247
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS18335
gene id: 1796613:A4V03_RS18335
uniprot id: A0A1C7H5Q5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1796613:A4V03 RS15950
gene id: 1796613:A4V03_RS15950
uniprot id: A0A1C7H4G2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1796613:A4V03 RS07035
gene id: 1796613:A4V03_RS07035
uniprot id: A0A1C7GYA6
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

1796613:A4V03 RS06705
gene id: 1796613:A4V03_RS06705
uniprot id: A0A1C7GXI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS14150
gene id: 1796613:A4V03_RS14150
uniprot id: A0A1C7H1U0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1796613:A4V03 RS14145
gene id: 1796613:A4V03_RS14145
uniprot id: A0A1C7H0V2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1796613:A4V03 RS10735
gene id: 1796613:A4V03_RS10735
uniprot id: A0A1C7GZX3
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS00165
gene id: 1796613:A4V03_RS00165
uniprot id: A0A1C7GX46
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1796613:A4V03 RS16615
gene id: 1796613:A4V03_RS16615
uniprot id: A0A1C7H4K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1796613:A4V03 RS14935
gene id: 1796613:A4V03_RS14935
uniprot id: A0A1C7H7I5
names: Similarity
messages: Belongs to the asparaginase 1 family.

1796613:A4V03 RS19465
gene id: 1796613:A4V03_RS19465
uniprot id: A0A1C7H5V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1796613:A4V03 RS04330
gene id: 1796613:A4V03_RS04330
uniprot id: A0A1C7GZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1796613:A4V03 RS01610
gene id: 1796613:A4V03_RS01610
uniprot id: A0A1C7GVQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1796613:A4V03 RS02905
gene id: 1796613:A4V03_RS02905
uniprot id: A0A1C7GYH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1796613:A4V03 RS06030
gene id: 1796613:A4V03_RS06030
uniprot id: A0A1C7GXS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1796613:A4V03 RS09315
gene id: 1796613:A4V03_RS09315
uniprot id: A0A1C7H1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1796613:A4V03 RS16775
gene id: 1796613:A4V03_RS16775
uniprot id: A0A1C7H5V7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1796613:A4V03 RS16650
gene id: 1796613:A4V03_RS16650
uniprot id: A0A1C7H2F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1796613:A4V03 RS02115
gene id: 1796613:A4V03_RS02115
uniprot id: A0A1C7GY53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1796613:A4V03 RS15975
gene id: 1796613:A4V03_RS15975
uniprot id: A0A1C7H2G0
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

1796613:A4V03 RS10120
gene id: 1796613:A4V03_RS10120
uniprot id: A0A1C7GZY9
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

1796613:A4V03 RS17305
gene id: 1796613:A4V03_RS17305
uniprot id: A0A1C7H545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS15910
gene id: 1796613:A4V03_RS15910
uniprot id: A0A1C7H2L0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796613:A4V03 RS09455
gene id: 1796613:A4V03_RS09455
uniprot id: A0A1C7GYP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1796613:A4V03 RS15985
gene id: 1796613:A4V03_RS15985
uniprot id: A0A1C7H769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1796613:A4V03 RS02610
gene id: 1796613:A4V03_RS02610
uniprot id: A0A1C7GXQ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1796613:A4V03 RS11780
gene id: 1796613:A4V03_RS11780
uniprot id: A0A1C7H0P6
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS03430
gene id: 1796613:A4V03_RS03430
uniprot id: A0A1C7GWW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS06805
gene id: 1796613:A4V03_RS06805
uniprot id: A0A1C7H182
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1796613:A4V03 RS13765
gene id: 1796613:A4V03_RS13765
uniprot id: A0A1C7H3D1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS20010
gene id: 1796613:A4V03_RS20010
uniprot id: A0A1C7H698
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1796613:A4V03 RS12760
gene id: 1796613:A4V03_RS12760
uniprot id: A0A1C7H2V0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1796613:A4V03 RS01385
gene id: 1796613:A4V03_RS01385
uniprot id: A0A1C7H3W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1796613:A4V03 RS03095
gene id: 1796613:A4V03_RS03095
uniprot id: A0A1C7GWQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1796613:A4V03 RS13830
gene id: 1796613:A4V03_RS13830
uniprot id: A0A1C7H3T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1796613:A4V03 RS02730
gene id: 1796613:A4V03_RS02730
uniprot id: A0A1C7GXT0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1796613:A4V03 RS18045
gene id: 1796613:A4V03_RS18045
uniprot id: A0A1C7H5L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1796613:A4V03 RS11485
gene id: 1796613:A4V03_RS11485
uniprot id: A0A1C7H267
names: Similarity
messages: Belongs to the manganese catalase family.

1796613:A4V03 RS06460
gene id: 1796613:A4V03_RS06460
uniprot id: A0A1C7GY18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1796613:A4V03 RS07375
gene id: 1796613:A4V03_RS07375
uniprot id: A0A1C7GYE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1796613:A4V03 RS12780
gene id: 1796613:A4V03_RS12780
uniprot id: A0A1C7H392
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796613:A4V03 RS11395
gene id: 1796613:A4V03_RS11395
uniprot id: A0A1C7H0F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1796613:A4V03 RS11265
gene id: 1796613:A4V03_RS11265
uniprot id: A0A1C7H2H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1796613:A4V03 RS18595
gene id: 1796613:A4V03_RS18595
uniprot id: A0A1C7H2X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1796613:A4V03 RS12700
gene id: 1796613:A4V03_RS12700
uniprot id: A0A1C7H3Y2
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1796613:A4V03 RS01005
gene id: 1796613:A4V03_RS01005
uniprot id: A0A1C7GXM9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS07005
gene id: 1796613:A4V03_RS07005
uniprot id: A0A1C7H0L0
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS15925
gene id: 1796613:A4V03_RS15925
uniprot id: A0A1C7H4C0
names: Similarity
messages: Belongs to the CvfB family.

1796613:A4V03 RS00650
gene id: 1796613:A4V03_RS00650
uniprot id: A0A1C7GXH2
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1796613:A4V03 RS00515
gene id: 1796613:A4V03_RS00515
uniprot id: A0A1C7GXA3
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS10805
gene id: 1796613:A4V03_RS10805
uniprot id: A0A1C7H2D2
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1796613:A4V03 RS06755
gene id: 1796613:A4V03_RS06755
uniprot id: A0A1C7GXJ3
names: Similarity
messages: Belongs to the aldose epimerase family.

1796613:A4V03 RS20020
gene id: 1796613:A4V03_RS20020
uniprot id: A0A1C7H7I2
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS16710
gene id: 1796613:A4V03_RS16710
uniprot id: A0A1C7H2X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1796613:A4V03 RS10490
gene id: 1796613:A4V03_RS10490
uniprot id: A0A1C7GZX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1796613:A4V03 RS00365
gene id: 1796613:A4V03_RS00365
uniprot id: A0A1C7GV52
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1796613:A4V03 RS00475
gene id: 1796613:A4V03_RS00475
uniprot id: A0A1C7GV70
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1796613:A4V03 RS15190
gene id: 1796613:A4V03_RS15190
uniprot id: A0A1C7H218
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1796613:A4V03 RS08980
gene id: 1796613:A4V03_RS08980
uniprot id: A0A1C7GZ83
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

1796613:A4V03 RS00455
gene id: 1796613:A4V03_RS00455
uniprot id: A0A1C7GX93
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS08510
gene id: 1796613:A4V03_RS08510
uniprot id: A0A1C7GZ05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1796613:A4V03 RS17330
gene id: 1796613:A4V03_RS17330
uniprot id: A0A1C7H4X7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1796613:A4V03 RS08800
gene id: 1796613:A4V03_RS08800
uniprot id: A0A1C7H593
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS00725
gene id: 1796613:A4V03_RS00725
uniprot id: A0A1C7H6Z0
names: Similarity
messages: Belongs to the Skp family.

1796613:A4V03 RS13195
gene id: 1796613:A4V03_RS13195
uniprot id: A0A1C7H0G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1796613:A4V03 RS19355
gene id: 1796613:A4V03_RS19355
uniprot id: A0A1C7H5Z2
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS11305
gene id: 1796613:A4V03_RS11305
uniprot id: A0A1C7H3A3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS16175
gene id: 1796613:A4V03_RS16175
uniprot id: A0A1C7H2J3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS19395
gene id: 1796613:A4V03_RS19395
uniprot id: A0A1C7H443
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS10010
gene id: 1796613:A4V03_RS10010
uniprot id: A0A1C7GYY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1796613:A4V03 RS04240
gene id: 1796613:A4V03_RS04240
uniprot id: A0A1C7GYM4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1796613:A4V03 RS11595
gene id: 1796613:A4V03_RS11595
uniprot id: A0A1C7H0D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism, and the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA).
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: In the N-terminal section; belongs to the radical SAM superfamily. Biotin synthase family.

1796613:A4V03 RS14590
gene id: 1796613:A4V03_RS14590
uniprot id: A0A1C7H1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1796613:A4V03 RS18455
gene id: 1796613:A4V03_RS18455
uniprot id: A0A1C7H3C8
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS13200
gene id: 1796613:A4V03_RS13200
uniprot id: A0A1C7H1D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1796613:A4V03 RS17170
gene id: 1796613:A4V03_RS17170
uniprot id: A0A1C7H4V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1796613:A4V03 RS16855
gene id: 1796613:A4V03_RS16855
uniprot id: A0A1C7H4Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796613:A4V03 RS08900
gene id: 1796613:A4V03_RS08900
uniprot id: A0A1C7H1F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1796613:A4V03 RS16070
gene id: 1796613:A4V03_RS16070
uniprot id: A0A1C7H4X2
names: Similarity
messages: Belongs to the ribF family.

1796613:A4V03 RS13750
gene id: 1796613:A4V03_RS13750
uniprot id: A0A1C7H5A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1796613:A4V03 RS13800
gene id: 1796613:A4V03_RS13800
uniprot id: A0A1C7H0Q7
names: Similarity
messages: Belongs to the citrate synthase family.

1796613:A4V03 RS00060
gene id: 1796613:A4V03_RS00060
uniprot id: A0A1C7GX28
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1796613:A4V03 RS11300
gene id: 1796613:A4V03_RS11300
uniprot id: A0A1C7H238
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1796613:A4V03 RS01450
gene id: 1796613:A4V03_RS01450
uniprot id: A0A1C7GXA7
names: Similarity
messages: Belongs to the XseB family.

1796613:A4V03 RS05925
gene id: 1796613:A4V03_RS05925
uniprot id: A0A1C7GXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1796613:A4V03 RS16105
gene id: 1796613:A4V03_RS16105
uniprot id: A0A1C7H5L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1796613:A4V03 RS11355
gene id: 1796613:A4V03_RS11355
uniprot id: A0A1C7H3B2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1796613:A4V03 RS10055
gene id: 1796613:A4V03_RS10055
uniprot id: A0A1C7H2Q9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1796613:A4V03 RS16690
gene id: 1796613:A4V03_RS16690
uniprot id: A0A1C7H563
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1796613:A4V03 RS14550
gene id: 1796613:A4V03_RS14550
uniprot id: A0A1C7H115
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1796613:A4V03 RS11705
gene id: 1796613:A4V03_RS11705
uniprot id: A0A1C7H0F6
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS15360
gene id: 1796613:A4V03_RS15360
uniprot id: A0A1C7H208
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS15245
gene id: 1796613:A4V03_RS15245
uniprot id: A0A1C7H5D2
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS11120
gene id: 1796613:A4V03_RS11120
uniprot id: A0A1C7H0A4
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS18630
gene id: 1796613:A4V03_RS18630
uniprot id: A0A1C7H3V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS05935
gene id: 1796613:A4V03_RS05935
uniprot id: A0A1C7H7G1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1796613:A4V03 RS13710
gene id: 1796613:A4V03_RS13710
uniprot id: A0A1C7H1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1796613:A4V03 RS11735
gene id: 1796613:A4V03_RS11735
uniprot id: A0A1C7H2Q7
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1796613:A4V03 RS07410
gene id: 1796613:A4V03_RS07410
uniprot id: A0A1C7H0K4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796613:A4V03 RS19850
gene id: 1796613:A4V03_RS19850
uniprot id: A0A1C7H7G2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1796613:A4V03 RS08535
gene id: 1796613:A4V03_RS08535
uniprot id: A0A1C7GZ53
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1796613:A4V03 RS00810
gene id: 1796613:A4V03_RS00810
uniprot id: A0A1C7GUR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1796613:A4V03 RS07515
gene id: 1796613:A4V03_RS07515
uniprot id: A0A1C7H0S9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1796613:A4V03 RS05490
gene id: 1796613:A4V03_RS05490
uniprot id: A0A1C7H4W4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1796613:A4V03 RS00760
gene id: 1796613:A4V03_RS00760
uniprot id: A0A1C7GWW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS17120
gene id: 1796613:A4V03_RS17120
uniprot id: A0A1C7H610
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1796613:A4V03 RS16685
gene id: 1796613:A4V03_RS16685
uniprot id: A0A1C7H2Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1796613:A4V03 RS06885
gene id: 1796613:A4V03_RS06885
uniprot id: A0A1C7H0D8
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1796613:A4V03 RS08515
gene id: 1796613:A4V03_RS08515
uniprot id: A0A1C7H0P2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1796613:A4V03 RS15220
gene id: 1796613:A4V03_RS15220
uniprot id: A0A1C7H4G1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1796613:A4V03 RS06840
gene id: 1796613:A4V03_RS06840
uniprot id: A0A1C7GY44
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS08880
gene id: 1796613:A4V03_RS08880
uniprot id: A0A1C7GYD4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1796613:A4V03 RS06420
gene id: 1796613:A4V03_RS06420
uniprot id: A0A1C7GXX5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS03495
gene id: 1796613:A4V03_RS03495
uniprot id: A0A1C7GYW0
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

1796613:A4V03 RS03260
gene id: 1796613:A4V03_RS03260
uniprot id: A0A1C7GYR6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796613:A4V03 RS03060
gene id: 1796613:A4V03_RS03060
uniprot id: A0A1C7GYM5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS16695
gene id: 1796613:A4V03_RS16695
uniprot id: A0A1C7H4P4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1796613:A4V03 RS11790
gene id: 1796613:A4V03_RS11790
uniprot id: A0A1C7H2D3
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1796613:A4V03 RS18950
gene id: 1796613:A4V03_RS18950
uniprot id: A0A1C7H3L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS17225
gene id: 1796613:A4V03_RS17225
uniprot id: A0A1C7H306
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS00480
gene id: 1796613:A4V03_RS00480
uniprot id: A0A1C7GV78
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS07505
gene id: 1796613:A4V03_RS07505
uniprot id: A0A1C7GXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1796613:A4V03 RS10405
gene id: 1796613:A4V03_RS10405
uniprot id: A0A1C7H236
names: Similarity
messages: Belongs to the CarB family.

1796613:A4V03 RS11660
gene id: 1796613:A4V03_RS11660
uniprot id: A0A1C7H294
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS18990
gene id: 1796613:A4V03_RS18990
uniprot id: A0A1C7H433
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1796613:A4V03 RS19590
gene id: 1796613:A4V03_RS19590
uniprot id: A0A1C7H6D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS03455
gene id: 1796613:A4V03_RS03455
uniprot id: A0A1C7GWM5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS15355
gene id: 1796613:A4V03_RS15355
uniprot id: A0A1C7H4H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS07495
gene id: 1796613:A4V03_RS07495
uniprot id: A0A1C7H084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS06550
gene id: 1796613:A4V03_RS06550
uniprot id: A0A1C7H089
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1796613:A4V03 RS12935
gene id: 1796613:A4V03_RS12935
uniprot id: A0A1C7H3B7
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS16705
gene id: 1796613:A4V03_RS16705
uniprot id: A0A1C7H2G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1796613:A4V03 RS16605
gene id: 1796613:A4V03_RS16605
uniprot id: A0A1C7H2V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1796613:A4V03 RS00720
gene id: 1796613:A4V03_RS00720
uniprot id: A0A1C7GVA8
names: Similarity
messages: Belongs to the Skp family.

1796613:A4V03 RS01050
gene id: 1796613:A4V03_RS01050
uniprot id: A0A1C7GX19
names: Similarity
messages: Belongs to the peptidase M13 family.

1796613:A4V03 RS18445
gene id: 1796613:A4V03_RS18445
uniprot id: A0A1C7H5T9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS10080
gene id: 1796613:A4V03_RS10080
uniprot id: A0A1C7H1Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796613:A4V03 RS00945
gene id: 1796613:A4V03_RS00945
uniprot id: A0A1C7H505
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS10435
gene id: 1796613:A4V03_RS10435
uniprot id: A0A1C7H1N9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1796613:A4V03 RS04410
gene id: 1796613:A4V03_RS04410
uniprot id: A0A1C7GXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1796613:A4V03 RS08685
gene id: 1796613:A4V03_RS08685
uniprot id: A0A1C7GZ01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1796613:A4V03 RS20025
gene id: 1796613:A4V03_RS20025
uniprot id: A0A1C7H3L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1796613:A4V03 RS06865
gene id: 1796613:A4V03_RS06865
uniprot id: A0A1C7GXL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS12000
gene id: 1796613:A4V03_RS12000
uniprot id: A0A1C7H0Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1796613:A4V03 RS16645
gene id: 1796613:A4V03_RS16645
uniprot id: A0A1C7H4X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1796613:A4V03 RS16915
gene id: 1796613:A4V03_RS16915
uniprot id: A0A1C7H4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1796613:A4V03 RS18735
gene id: 1796613:A4V03_RS18735
uniprot id: A0A1C7H3W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1796613:A4V03 RS13745
gene id: 1796613:A4V03_RS13745
uniprot id: A0A1C7H1M7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1796613:A4V03 RS14220
gene id: 1796613:A4V03_RS14220
uniprot id: A0A1C7H1J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1796613:A4V03 RS20130
gene id: 1796613:A4V03_RS20130
uniprot id: A0A1C7H3N7
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS11630
gene id: 1796613:A4V03_RS11630
uniprot id: A0A1C7H5D9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1796613:A4V03 RS02655
gene id: 1796613:A4V03_RS02655
uniprot id: A0A1C7GWI2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS01905
gene id: 1796613:A4V03_RS01905
uniprot id: A0A1C7GXL4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1796613:A4V03 RS20000
gene id: 1796613:A4V03_RS20000
uniprot id: A0A1C7H4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1796613:A4V03 RS17795
gene id: 1796613:A4V03_RS17795
uniprot id: A0A1C7H6C2
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS06555
gene id: 1796613:A4V03_RS06555
uniprot id: A0A1C7GZR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1796613:A4V03 RS14540
gene id: 1796613:A4V03_RS14540
uniprot id: A0A1C7H3Q6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS12360
gene id: 1796613:A4V03_RS12360
uniprot id: A0A1C7H3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1796613:A4V03 RS09550
gene id: 1796613:A4V03_RS09550
uniprot id: A0A1C7H184
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1796613:A4V03 RS05965
gene id: 1796613:A4V03_RS05965
uniprot id: A0A1C7GZY5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS08385
gene id: 1796613:A4V03_RS08385
uniprot id: A0A1C7H0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS14425
gene id: 1796613:A4V03_RS14425
uniprot id: A0A1C7H1Z3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1796613:A4V03 RS19860
gene id: 1796613:A4V03_RS19860
uniprot id: A0A1C7H4E9
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1796613:A4V03 RS02320
gene id: 1796613:A4V03_RS02320
uniprot id: A0A1C7GW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS02800
gene id: 1796613:A4V03_RS02800
uniprot id: A0A1C7GWE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS16210
gene id: 1796613:A4V03_RS16210
uniprot id: A0A1C7H5E9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796613:A4V03 RS16375
gene id: 1796613:A4V03_RS16375
uniprot id: A0A1C7H5M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1796613:A4V03 RS10355
gene id: 1796613:A4V03_RS10355
uniprot id: A0A1C7H7M0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1796613:A4V03 RS09030
gene id: 1796613:A4V03_RS09030
uniprot id: A0A1C7GZ56
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS12520
gene id: 1796613:A4V03_RS12520
uniprot id: A0A1C7H2R4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS11760
gene id: 1796613:A4V03_RS11760
uniprot id: A0A1C7H0G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS20375
gene id: 1796613:A4V03_RS20375
uniprot id: A0A1C7H4J3
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS06845
gene id: 1796613:A4V03_RS06845
uniprot id: A0A1C7GY74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1796613:A4V03 RS10450
gene id: 1796613:A4V03_RS10450
uniprot id: A0A1C7H054
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1796613:A4V03 RS13075
gene id: 1796613:A4V03_RS13075
uniprot id: A0A1C7H130
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1796613:A4V03 RS19490
gene id: 1796613:A4V03_RS19490
uniprot id: A0A1C7H418
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS11575
gene id: 1796613:A4V03_RS11575
uniprot id: A0A1C7H297
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS00290
gene id: 1796613:A4V03_RS00290
uniprot id: A0A1C7GVE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

1796613:A4V03 RS19940
gene id: 1796613:A4V03_RS19940
uniprot id: A0A1C7H4B6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1796613:A4V03 RS01690
gene id: 1796613:A4V03_RS01690
uniprot id: A0A1C7GYN3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS02900
gene id: 1796613:A4V03_RS02900
uniprot id: A0A1C7GXV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1796613:A4V03 RS13725
gene id: 1796613:A4V03_RS13725
uniprot id: A0A1C7H3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1796613:A4V03 RS10465
gene id: 1796613:A4V03_RS10465
uniprot id: A0A1C7H284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS02510
gene id: 1796613:A4V03_RS02510
uniprot id: A0A1C7GXN9
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1796613:A4V03 RS15980
gene id: 1796613:A4V03_RS15980
uniprot id: A0A1C7H4C9
names: Similarity
messages: Belongs to the Fur family.

1796613:A4V03 RS10045
gene id: 1796613:A4V03_RS10045
uniprot id: A0A1C7GZP7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1796613:A4V03 RS16850
gene id: 1796613:A4V03_RS16850
uniprot id: A0A1C7H2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1796613:A4V03 RS13330
gene id: 1796613:A4V03_RS13330
uniprot id: A0A1C7H169
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1796613:A4V03 RS01940
gene id: 1796613:A4V03_RS01940
uniprot id: A0A1C7GW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1796613:A4V03 RS07365
gene id: 1796613:A4V03_RS07365
uniprot id: A0A1C7H830
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1796613:A4V03 RS06520
gene id: 1796613:A4V03_RS06520
uniprot id: A0A1C7H7H1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS08810
gene id: 1796613:A4V03_RS08810
uniprot id: A0A1C7H265
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1796613:A4V03 RS16495
gene id: 1796613:A4V03_RS16495
uniprot id: A0A1C7H2U0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS02030
gene id: 1796613:A4V03_RS02030
uniprot id: A0A1C7GYT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1796613:A4V03 RS18870
gene id: 1796613:A4V03_RS18870
uniprot id: A0A1C7H6F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1796613:A4V03 RS09420
gene id: 1796613:A4V03_RS09420
uniprot id: A0A1C7H119
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1796613:A4V03 RS09855
gene id: 1796613:A4V03_RS09855
uniprot id: A0A1C7H190
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1796613:A4V03 RS02055
gene id: 1796613:A4V03_RS02055
uniprot id: A0A1C7GXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1796613:A4V03 RS10520
gene id: 1796613:A4V03_RS10520
uniprot id: A0A1C7H1R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1796613:A4V03 RS04325
gene id: 1796613:A4V03_RS04325
uniprot id: A0A1C7GYV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1796613:A4V03 RS11370
gene id: 1796613:A4V03_RS11370
uniprot id: A0A1C7H0I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1796613:A4V03 RS08620
gene id: 1796613:A4V03_RS08620
uniprot id: A0A1C7GYZ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1796613:A4V03 RS00415
gene id: 1796613:A4V03_RS00415
uniprot id: A0A1C7GXD8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1796613:A4V03 RS09430
gene id: 1796613:A4V03_RS09430
uniprot id: A0A1C7GZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1796613:A4V03 RS09460
gene id: 1796613:A4V03_RS09460
uniprot id: A0A1C7H7L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1796613:A4V03 RS00510
gene id: 1796613:A4V03_RS00510
uniprot id: A0A1C7GVJ0
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS13370
gene id: 1796613:A4V03_RS13370
uniprot id: A0A1C7H3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1796613:A4V03 RS03315
gene id: 1796613:A4V03_RS03315
uniprot id: A0A1C7GYT3
names: Similarity
messages: Belongs to the peptidase C1 family.

1796613:A4V03 RS15200
gene id: 1796613:A4V03_RS15200
uniprot id: A0A1C7H567
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1796613:A4V03 RS16820
gene id: 1796613:A4V03_RS16820
uniprot id: A0A1C7H583
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1796613:A4V03 RS11895
gene id: 1796613:A4V03_RS11895
uniprot id: A0A1C7H3K1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1796613:A4V03 RS19420
gene id: 1796613:A4V03_RS19420
uniprot id: A0A1C7H6Q1
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS04175
gene id: 1796613:A4V03_RS04175
uniprot id: A0A1C7GWA8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1796613:A4V03 RS11655
gene id: 1796613:A4V03_RS11655
uniprot id: A0A1C7H0E8
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS19325
gene id: 1796613:A4V03_RS19325
uniprot id: A0A1C7H6N4
names: Subcellular Location Annotation
messages: Cytoplasm

1796613:A4V03 RS02820
gene id: 1796613:A4V03_RS02820
uniprot id: A0A1C7GZ72
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS19200
gene id: 1796613:A4V03_RS19200
uniprot id: A0A1C7H480
names: Similarity
messages: Belongs to the DEAD box helicase family.

1796613:A4V03 RS05810
gene id: 1796613:A4V03_RS05810
uniprot id: A0A1C7GXM4
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS04165
gene id: 1796613:A4V03_RS04165
uniprot id: A0A1C7GYP7
names: Similarity
messages: Belongs to the HsdR family.

1796613:A4V03 RS07295
gene id: 1796613:A4V03_RS07295
uniprot id: A0A1C7GYD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS02750
gene id: 1796613:A4V03_RS02750
uniprot id: A0A1C7GW96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1796613:A4V03 RS19825
gene id: 1796613:A4V03_RS19825
uniprot id: A0A1C7H471
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1796613:A4V03 RS16630
gene id: 1796613:A4V03_RS16630
uniprot id: A0A1C7H2X2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1796613:A4V03 RS04840
gene id: 1796613:A4V03_RS04840
uniprot id: A0A1C7H526
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1796613:A4V03 RS06925
gene id: 1796613:A4V03_RS06925
uniprot id: A0A1C7GXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1796613:A4V03 RS16610
gene id: 1796613:A4V03_RS16610
uniprot id: A0A1C7H2Q3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1796613:A4V03 RS08885
gene id: 1796613:A4V03_RS08885
uniprot id: A0A1C7GZE0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1796613:A4V03 RS01585
gene id: 1796613:A4V03_RS01585
uniprot id: A0A1C7GXX8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1796613:A4V03 RS01760
gene id: 1796613:A4V03_RS01760
uniprot id: A0A1C7GY23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1796613:A4V03 RS01210
gene id: 1796613:A4V03_RS01210
uniprot id: A0A1C7GYE9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1796613:A4V03 RS13445
gene id: 1796613:A4V03_RS13445
uniprot id: A0A1C7H363
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1796613:A4V03 RS01020
gene id: 1796613:A4V03_RS01020
uniprot id: A0A1C7GVG2
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS01100
gene id: 1796613:A4V03_RS01100
uniprot id: A0A1C7GX26
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1796613:A4V03 RS08850
gene id: 1796613:A4V03_RS08850
uniprot id: A0A1C7H1E5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1796613:A4V03 RS15840
gene id: 1796613:A4V03_RS15840
uniprot id: A0A1C7H4T5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1796613:A4V03 RS13850
gene id: 1796613:A4V03_RS13850
uniprot id: A0A1C7H1F6
names: Similarity
messages: Belongs to the UPF0597 family.

1796613:A4V03 RS19280
gene id: 1796613:A4V03_RS19280
uniprot id: A0A1C7H663
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1796613:A4V03 RS11165
gene id: 1796613:A4V03_RS11165
uniprot id: A0A1C7H028
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1796613:A4V03 RS09735
gene id: 1796613:A4V03_RS09735
uniprot id: A0A1C7H1V6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1796613:A4V03 RS15540
gene id: 1796613:A4V03_RS15540
uniprot id: A0A1C7H758
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1796613:A4V03 RS20240
gene id: 1796613:A4V03_RS20240
uniprot id: A0A1C7H6N2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS10230
gene id: 1796613:A4V03_RS10230
uniprot id: A0A1C7H230
names: Similarity
messages: Belongs to the CapA family.

1796613:A4V03 RS08675
gene id: 1796613:A4V03_RS08675
uniprot id: A0A1C7H0P9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1796613:A4V03 RS09360
gene id: 1796613:A4V03_RS09360
uniprot id: A0A1C7GZM0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1796613:A4V03 RS10830
gene id: 1796613:A4V03_RS10830
uniprot id: A0A1C7H337
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

1796613:A4V03 RS09845
gene id: 1796613:A4V03_RS09845
uniprot id: A0A1C7H1Y0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1796613:A4V03 RS01485
gene id: 1796613:A4V03_RS01485
uniprot id: A0A1C7GXT7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796613:A4V03 RS00045
gene id: 1796613:A4V03_RS00045
uniprot id: A0A1C7GXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1796613:A4V03 RS16500
gene id: 1796613:A4V03_RS16500
uniprot id: A0A1C7H2N0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796613:A4V03 RS17350
gene id: 1796613:A4V03_RS17350
uniprot id: A0A1C7H5N3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1796613:A4V03 RS10070
gene id: 1796613:A4V03_RS10070
uniprot id: A0A1C7H224
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796613:A4V03 RS08740
gene id: 1796613:A4V03_RS08740
uniprot id: A0A1C7GZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1796613:A4V03 RS02110
gene id: 1796613:A4V03_RS02110
uniprot id: A0A1C7GXI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1796613:A4V03 RS13415
gene id: 1796613:A4V03_RS13415
uniprot id: A0A1C7H366
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1796613:A4V03 RS06660
gene id: 1796613:A4V03_RS06660
uniprot id: A0A1C7GYC2
names: Similarity
messages: Belongs to the transketolase family.

1796613:A4V03 RS12365
gene id: 1796613:A4V03_RS12365
uniprot id: A0A1C7H035
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1796613:A4V03 RS04820
gene id: 1796613:A4V03_RS04820
uniprot id: A0A1C7GXA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS14620
gene id: 1796613:A4V03_RS14620
uniprot id: A0A1C7H5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS19765
gene id: 1796613:A4V03_RS19765
uniprot id: A0A1C7H6E8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796613:A4V03 RS12845
gene id: 1796613:A4V03_RS12845
uniprot id: A0A1C7H152
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1796613:A4V03 RS10740
gene id: 1796613:A4V03_RS10740
uniprot id: A0A1C7H048
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1796613:A4V03 RS10025
gene id: 1796613:A4V03_RS10025
uniprot id: A0A1V0QD67
names: Similarity
messages: Belongs to the UPF0047 family.

1796613:A4V03 RS00535
gene id: 1796613:A4V03_RS00535
uniprot id: A0A1C7GV80
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1796613:A4V03 RS11055
gene id: 1796613:A4V03_RS11055
uniprot id: A0A1C7H094
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS00135
gene id: 1796613:A4V03_RS00135
uniprot id: A0A1C7GV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1796613:A4V03 RS09080
gene id: 1796613:A4V03_RS09080
uniprot id: A0A1C7GZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1796613:A4V03 RS02815
gene id: 1796613:A4V03_RS02815
uniprot id: A0A1C7GY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS01685
gene id: 1796613:A4V03_RS01685
uniprot id: A0A1C7GXH0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1796613:A4V03 RS00815
gene id: 1796613:A4V03_RS00815
uniprot id: A0A1C7GVN6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1796613:A4V03 RS16655
gene id: 1796613:A4V03_RS16655
uniprot id: A0A1C7H2W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1796613:A4V03 RS18835
gene id: 1796613:A4V03_RS18835
uniprot id: A0A1C7H3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1796613:A4V03 RS00430
gene id: 1796613:A4V03_RS00430
uniprot id: A0A1C7GV72
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1796613:A4V03 RS02130
gene id: 1796613:A4V03_RS02130
uniprot id: A0A1C7GVZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1796613:A4V03 RS16660
gene id: 1796613:A4V03_RS16660
uniprot id: A0A1C7H2R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1796613:A4V03 RS03105
gene id: 1796613:A4V03_RS03105
uniprot id: A0A1C7GY02
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS15440
gene id: 1796613:A4V03_RS15440
uniprot id: A0A1C7H5A6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS09135
gene id: 1796613:A4V03_RS09135
uniprot id: A0A1C7H0X0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS02285
gene id: 1796613:A4V03_RS02285
uniprot id: A0A1C7GWD0
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS18415
gene id: 1796613:A4V03_RS18415
uniprot id: A0A1C7H3M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS13545
gene id: 1796613:A4V03_RS13545
uniprot id: A0A1C7H172
names: Similarity
messages: Belongs to the peptidase S9A family.

1796613:A4V03 RS12855
gene id: 1796613:A4V03_RS12855
uniprot id: A0A1C7H2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1796613:A4V03 RS02925
gene id: 1796613:A4V03_RS02925
uniprot id: A0A1C7GY51
names: Similarity
messages: Belongs to the peptidase M16 family.

1796613:A4V03 RS14880
gene id: 1796613:A4V03_RS14880
uniprot id: A0A1C7H1T9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1796613:A4V03 RS10410
gene id: 1796613:A4V03_RS10410
uniprot id: A0A1C7H1J2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1796613:A4V03 RS09075
gene id: 1796613:A4V03_RS09075
uniprot id: A0A1C7H1I5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1796613:A4V03 RS06740
gene id: 1796613:A4V03_RS06740
uniprot id: A0A1C7GY37
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS00630
gene id: 1796613:A4V03_RS00630
uniprot id: A0A1C7GVK9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS02545
gene id: 1796613:A4V03_RS02545
uniprot id: A0A1C7GVI6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796613:A4V03 RS08855
gene id: 1796613:A4V03_RS08855
uniprot id: A0A1C7GZ40
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS04465
gene id: 1796613:A4V03_RS04465
uniprot id: A0A1C7GWG0
names: Similarity
messages: Belongs to the NusB family.

1796613:A4V03 RS10280
gene id: 1796613:A4V03_RS10280
uniprot id: A0A1C7H232
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1796613:A4V03 RS08990
gene id: 1796613:A4V03_RS08990
uniprot id: A0A1C7H291
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1796613:A4V03 RS11065
gene id: 1796613:A4V03_RS11065
uniprot id: A0A1C7H1Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1796613:A4V03 RS10050
gene id: 1796613:A4V03_RS10050
uniprot id: A0A1C7H1G9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1796613:A4V03 RS08470
gene id: 1796613:A4V03_RS08470
uniprot id: A0A1C7GZ44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS16020
gene id: 1796613:A4V03_RS16020
uniprot id: A0A1C7H4H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1796613:A4V03 RS13360
gene id: 1796613:A4V03_RS13360
uniprot id: A0A1C7H3I6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1796613:A4V03 RS19385
gene id: 1796613:A4V03_RS19385
uniprot id: A0A1C7H3Z9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS16295
gene id: 1796613:A4V03_RS16295
uniprot id: A0A1C7H5C9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1796613:A4V03 RS17885
gene id: 1796613:A4V03_RS17885
uniprot id: A0A1C7H328
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS14450
gene id: 1796613:A4V03_RS14450
uniprot id: A0A1C7H1W8
names: Similarity
messages: Belongs to the UPF0102 family.

1796613:A4V03 RS14245
gene id: 1796613:A4V03_RS14245
uniprot id: A0A1C7H0W9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1796613:A4V03 RS13560
gene id: 1796613:A4V03_RS13560
uniprot id: A0A1C7H381
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1796613:A4V03 RS00425
gene id: 1796613:A4V03_RS00425
uniprot id: A0A1C7GV62
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS18525
gene id: 1796613:A4V03_RS18525
uniprot id: A0A1C7H3N9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS13825
gene id: 1796613:A4V03_RS13825
uniprot id: A0A1C7H3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1796613:A4V03 RS10510
gene id: 1796613:A4V03_RS10510
uniprot id: A0A1C7H064
names: Similarity
messages: Belongs to the TrpC family.

1796613:A4V03 RS01570
gene id: 1796613:A4V03_RS01570
uniprot id: A0A1C7GYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1796613:A4V03 RS17175
gene id: 1796613:A4V03_RS17175
uniprot id: A0A1C7H620
names: Similarity
messages: Belongs to the peptidase S41A family.

1796613:A4V03 RS00185
gene id: 1796613:A4V03_RS00185
uniprot id: A0A1C7GXA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS06715
gene id: 1796613:A4V03_RS06715
uniprot id: A0A1C7H0B7
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS10505
gene id: 1796613:A4V03_RS10505
uniprot id: A0A1C7GZ85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS05880
gene id: 1796613:A4V03_RS05880
uniprot id: A0A1C7GX36
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1796613:A4V03 RS19365
gene id: 1796613:A4V03_RS19365
uniprot id: A0A1C7H3A0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS02575
gene id: 1796613:A4V03_RS02575
uniprot id: A0A1C7GW60
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1796613:A4V03 RS13010
gene id: 1796613:A4V03_RS13010
uniprot id: A0A1C7H0Y8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1796613:A4V03 RS02290
gene id: 1796613:A4V03_RS02290
uniprot id: A0A1C7GYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS06050
gene id: 1796613:A4V03_RS06050
uniprot id: A0A1C7GX75
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS16525
gene id: 1796613:A4V03_RS16525
uniprot id: A0A1C7H532
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS12665
gene id: 1796613:A4V03_RS12665
uniprot id: A0A1C7H399
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1796613:A4V03 RS15425
gene id: 1796613:A4V03_RS15425
uniprot id: A0A1C7H2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1796613:A4V03 RS07255
gene id: 1796613:A4V03_RS07255
uniprot id: A0A1C7GXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1796613:A4V03 RS07185
gene id: 1796613:A4V03_RS07185
uniprot id: A0A1C7H030
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS00835
gene id: 1796613:A4V03_RS00835
uniprot id: A0A1C7GVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1796613:A4V03 RS11725
gene id: 1796613:A4V03_RS11725
uniprot id: A0A1C7H0N5
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1796613:A4V03 RS13690
gene id: 1796613:A4V03_RS13690
uniprot id: A0A1C7H1L7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1796613:A4V03 RS10090
gene id: 1796613:A4V03_RS10090
uniprot id: A0A1C7GZN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796613:A4V03 RS14415
gene id: 1796613:A4V03_RS14415
uniprot id: A0A1C7H4V3
names: Similarity
messages: Belongs to the thioredoxin family.

1796613:A4V03 RS18745
gene id: 1796613:A4V03_RS18745
uniprot id: A0A1C7H5M6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1796613:A4V03 RS12725
gene id: 1796613:A4V03_RS12725
uniprot id: A0A1C7H5J9
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1796613:A4V03 RS06470
gene id: 1796613:A4V03_RS06470
uniprot id: A0A1C7GXY0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1796613:A4V03 RS06180
gene id: 1796613:A4V03_RS06180
uniprot id: A0A1C7GY30
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1796613:A4V03 RS14595
gene id: 1796613:A4V03_RS14595
uniprot id: A0A1C7H3R3
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS14650
gene id: 1796613:A4V03_RS14650
uniprot id: A0A1C7H3R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS18580
gene id: 1796613:A4V03_RS18580
uniprot id: A0A1C7H5K3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS00550
gene id: 1796613:A4V03_RS00550
uniprot id: A0A1C7H3V4
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS13810
gene id: 1796613:A4V03_RS13810
uniprot id: A0A1C7H3R2
names: Subcellular Location Annotation
messages: Mitochondrion

1796613:A4V03 RS18100
gene id: 1796613:A4V03_RS18100
uniprot id: A0A1C7H5N0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1796613:A4V03 RS14680
gene id: 1796613:A4V03_RS14680
uniprot id: A0A1C7H3Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1796613:A4V03 RS00205
gene id: 1796613:A4V03_RS00205
uniprot id: A0A1C7GWL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS01720
gene id: 1796613:A4V03_RS01720
uniprot id: A0A1C7GVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS14050
gene id: 1796613:A4V03_RS14050
uniprot id: A0A1C7H3X1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS01480
gene id: 1796613:A4V03_RS01480
uniprot id: A0A1C7GX89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS18125
gene id: 1796613:A4V03_RS18125
uniprot id: A0A1C7H3H8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS13130
gene id: 1796613:A4V03_RS13130
uniprot id: A0A1C7H316
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1796613:A4V03 RS07205
gene id: 1796613:A4V03_RS07205
uniprot id: A0A1C7GYK8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1796613:A4V03 RS08505
gene id: 1796613:A4V03_RS08505
uniprot id: A0A1C7GYX2
names: Similarity
messages: Belongs to the CinA family.

1796613:A4V03 RS01410
gene id: 1796613:A4V03_RS01410
uniprot id: A0A1C7GV02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1796613:A4V03 RS12945
gene id: 1796613:A4V03_RS12945
uniprot id: A0A1C7H3E5
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS09750
gene id: 1796613:A4V03_RS09750
uniprot id: A0A1C7GZE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1796613:A4V03 RS05930
gene id: 1796613:A4V03_RS05930
uniprot id: A0A1C7GZH0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1796613:A4V03 RS19345
gene id: 1796613:A4V03_RS19345
uniprot id: A0A1C7H482
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1796613:A4V03 RS18310
gene id: 1796613:A4V03_RS18310
uniprot id: A0A1C7H6L9
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1796613:A4V03 RS13670
gene id: 1796613:A4V03_RS13670
uniprot id: A0A1C7H1C9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS12010
gene id: 1796613:A4V03_RS12010
uniprot id: A0A1C7H2G8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1796613:A4V03 RS08500
gene id: 1796613:A4V03_RS08500
uniprot id: A0A1C7GYX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1796613:A4V03 RS12940
gene id: 1796613:A4V03_RS12940
uniprot id: A0A1C7H2Y4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1796613:A4V03 RS10790
gene id: 1796613:A4V03_RS10790
uniprot id: A0A1C7H298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1796613:A4V03 RS07020
gene id: 1796613:A4V03_RS07020
uniprot id: A0A1C7H4Z5
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1796613:A4V03 RS02060
gene id: 1796613:A4V03_RS02060
uniprot id: A0A1C7GY34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796613:A4V03 RS01565
gene id: 1796613:A4V03_RS01565
uniprot id: A0A1C7GXF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1796613:A4V03 RS13760
gene id: 1796613:A4V03_RS13760
uniprot id: A0A1C7H3Q7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1796613:A4V03 RS07200
gene id: 1796613:A4V03_RS07200
uniprot id: A0A1C7GXP9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS12755
gene id: 1796613:A4V03_RS12755
uniprot id: A0A1C7H0W5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS17810
gene id: 1796613:A4V03_RS17810
uniprot id: A0A1C7H5P2
names: Similarity
messages: Belongs to the pyruvate kinase family.

1796613:A4V03 RS08355
gene id: 1796613:A4V03_RS08355
uniprot id: A0A1C7H0J7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1796613:A4V03 RS00885
gene id: 1796613:A4V03_RS00885
uniprot id: A0A1C7GXK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1796613:A4V03 RS18370
gene id: 1796613:A4V03_RS18370
uniprot id: A0A1C7H6M8
names: Similarity
messages: Belongs to the glycosyl hydrolase 66 family.

1796613:A4V03 RS02770
gene id: 1796613:A4V03_RS02770
uniprot id: A0A1C7GVM5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1796613:A4V03 RS01620
gene id: 1796613:A4V03_RS01620
uniprot id: A0A1C7GXF5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1796613:A4V03 RS05730
gene id: 1796613:A4V03_RS05730
uniprot id: A0A1C7GZU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS03365
gene id: 1796613:A4V03_RS03365
uniprot id: A0A1C7GVY0
names: Similarity
messages: Belongs to the FGGY kinase family.

1796613:A4V03 RS01815
gene id: 1796613:A4V03_RS01815
uniprot id: A0A1C7GY41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS00995
gene id: 1796613:A4V03_RS00995
uniprot id: A0A1C7GXK5
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS14905
gene id: 1796613:A4V03_RS14905
uniprot id: A0A1C7H175
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1796613:A4V03 RS01205
gene id: 1796613:A4V03_RS01205
uniprot id: A0A1C7GX67
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1796613:A4V03 RS18090
gene id: 1796613:A4V03_RS18090
uniprot id: A0A1C7H5I0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1796613:A4V03 RS10835
gene id: 1796613:A4V03_RS10835
uniprot id: A0A1C7GZE3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1796613:A4V03 RS11400
gene id: 1796613:A4V03_RS11400
uniprot id: A0A1C7H0B0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1796613:A4V03 RS15165
gene id: 1796613:A4V03_RS15165
uniprot id: A0A1C7H459
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS06145
gene id: 1796613:A4V03_RS06145
uniprot id: A0A1C7GXU4
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1796613:A4V03 RS10565
gene id: 1796613:A4V03_RS10565
uniprot id: A0A1C7H2Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS17915
gene id: 1796613:A4V03_RS17915
uniprot id: A0A1C7H2K2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796613:A4V03 RS20055
gene id: 1796613:A4V03_RS20055
uniprot id: A0A1C7H4Q8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1796613:A4V03 RS19580
gene id: 1796613:A4V03_RS19580
uniprot id: A0A1C7H6R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS18380
gene id: 1796613:A4V03_RS18380
uniprot id: A0A1C7H2T4
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS05975
gene id: 1796613:A4V03_RS05975
uniprot id: A0A1C7GXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS06080
gene id: 1796613:A4V03_RS06080
uniprot id: A0A1C7GXX4
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1796613:A4V03 RS19495
gene id: 1796613:A4V03_RS19495
uniprot id: A0A1C7H4B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS01405
gene id: 1796613:A4V03_RS01405
uniprot id: A0A1C7H4Q0
names: Similarity
messages: Belongs to the SUI1 family.

1796613:A4V03 RS07055
gene id: 1796613:A4V03_RS07055
uniprot id: A0A1C7H1C3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1796613:A4V03 RS01710
gene id: 1796613:A4V03_RS01710
uniprot id: A0A1C7GXC4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1796613:A4V03 RS00845
gene id: 1796613:A4V03_RS00845
uniprot id: A0A1C7GVD4
names: Caution
names: Function
names: Similarity
messages: Belongs to the rhamnulokinase family.
messages: Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS01900
gene id: 1796613:A4V03_RS01900
uniprot id: A0A1C7GVW6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1796613:A4V03 RS16735
gene id: 1796613:A4V03_RS16735
uniprot id: A0A1C7H2Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1796613:A4V03 RS05980
gene id: 1796613:A4V03_RS05980
uniprot id: A0A1C7GXS6
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS13820
gene id: 1796613:A4V03_RS13820
uniprot id: A0A1C7H7H5
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

1796613:A4V03 RS14915
gene id: 1796613:A4V03_RS14915
uniprot id: A0A1C7H283
names: Similarity
messages: Belongs to the threonine synthase family.

1796613:A4V03 RS16760
gene id: 1796613:A4V03_RS16760
uniprot id: A0A1C7H2Z0
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

1796613:A4V03 RS01335
gene id: 1796613:A4V03_RS01335
uniprot id: A0A1C7GUZ4
names: Similarity
messages: Belongs to the UPF0246 family.

1796613:A4V03 RS07975
gene id: 1796613:A4V03_RS07975
uniprot id: A0A1C7GYN6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1796613:A4V03 RS12400
gene id: 1796613:A4V03_RS12400
uniprot id: A0A1C7H0R1
names: Similarity
messages: Belongs to the CapA family.

1796613:A4V03 RS09320
gene id: 1796613:A4V03_RS09320
uniprot id: A0A1C7GZ89
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS20110
gene id: 1796613:A4V03_RS20110
uniprot id: A0A1C7H4N6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS12505
gene id: 1796613:A4V03_RS12505
uniprot id: A0A1C7H0P3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS13550
gene id: 1796613:A4V03_RS13550
uniprot id: A0A1C7H1H4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1796613:A4V03 RS14155
gene id: 1796613:A4V03_RS14155
uniprot id: A0A1C7H3W3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1796613:A4V03 RS07315
gene id: 1796613:A4V03_RS07315
uniprot id: A0A1C7H566
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1796613:A4V03 RS18420
gene id: 1796613:A4V03_RS18420
uniprot id: A0A1C7H5H8
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS08410
gene id: 1796613:A4V03_RS08410
uniprot id: A0A1C7H192
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1796613:A4V03 RS11015
gene id: 1796613:A4V03_RS11015
uniprot id: A0A1C7GZG3
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS02090
gene id: 1796613:A4V03_RS02090
uniprot id: A0A1C7GVC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1796613:A4V03 RS11340
gene id: 1796613:A4V03_RS11340
uniprot id: A0A1C7H0E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1796613:A4V03 RS04450
gene id: 1796613:A4V03_RS04450
uniprot id: A0A1C7H6Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1796613:A4V03 RS06720
gene id: 1796613:A4V03_RS06720
uniprot id: A0A1C7GZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS10420
gene id: 1796613:A4V03_RS10420
uniprot id: A0A1C7GZT2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS02070
gene id: 1796613:A4V03_RS02070
uniprot id: A0A1C7GVY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796613:A4V03 RS07570
gene id: 1796613:A4V03_RS07570
uniprot id: A0A1C7H4Y1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1796613:A4V03 RS14420
gene id: 1796613:A4V03_RS14420
uniprot id: A0A1C7H0Z5
names: Subcellular Location Annotation
messages: Cytoplasm

1796613:A4V03 RS10460
gene id: 1796613:A4V03_RS10460
uniprot id: A0A1C7H1R0
names: Similarity
messages: Belongs to the P(II) protein family.

1796613:A4V03 RS02065
gene id: 1796613:A4V03_RS02065
uniprot id: A0A1C7GW30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796613:A4V03 RS08845
gene id: 1796613:A4V03_RS08845
uniprot id: A0A1C7H0S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1796613:A4V03 RS16635
gene id: 1796613:A4V03_RS16635
uniprot id: A0A1C7H554
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1796613:A4V03 RS09435
gene id: 1796613:A4V03_RS09435
uniprot id: A0A1C7GZD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1796613:A4V03 RS11110
gene id: 1796613:A4V03_RS11110
uniprot id: A0A1C7H019
names: Similarity
messages: Belongs to the peptidase C40 family.

1796613:A4V03 RS03170
gene id: 1796613:A4V03_RS03170
uniprot id: A0A1C7GWH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1796613:A4V03 RS14100
gene id: 1796613:A4V03_RS14100
uniprot id: A0A1C7H3V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1796613:A4V03 RS14995
gene id: 1796613:A4V03_RS14995
uniprot id: A0A1C7H185
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796613:A4V03 RS16050
gene id: 1796613:A4V03_RS16050
uniprot id: A0A1C7H4D2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS17800
gene id: 1796613:A4V03_RS17800
uniprot id: A0A1C7H2I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1796613:A4V03 RS01320
gene id: 1796613:A4V03_RS01320
uniprot id: A0A1C7GX90
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1796613:A4V03 RS12170
gene id: 1796613:A4V03_RS12170
uniprot id: A0A1C7H0S7
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1796613:A4V03 RS01390
gene id: 1796613:A4V03_RS01390
uniprot id: A0A1C7GVM2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1796613:A4V03 RS12015
gene id: 1796613:A4V03_RS12015
uniprot id: A0A1C7H3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1796613:A4V03 RS04800
gene id: 1796613:A4V03_RS04800
uniprot id: A0A1C7GZG5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS19550
gene id: 1796613:A4V03_RS19550
uniprot id: A0A1C7H4C6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1796613:A4V03 RS09545
gene id: 1796613:A4V03_RS09545
uniprot id: A0A1C7GZH2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1796613:A4V03 RS16745
gene id: 1796613:A4V03_RS16745
uniprot id: A0A1C7H4Q3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1796613:A4V03 RS16835
gene id: 1796613:A4V03_RS16835
uniprot id: A0A1C7H511
names: Similarity
messages: Belongs to the peptidase M24B family.

1796613:A4V03 RS17665
gene id: 1796613:A4V03_RS17665
uniprot id: A0A1C7H3D7
names: Similarity
messages: Belongs to the ParB family.

1796613:A4V03 RS14980
gene id: 1796613:A4V03_RS14980
uniprot id: A0A1C7H3V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1796613:A4V03 RS20265
gene id: 1796613:A4V03_RS20265
uniprot id: A0A1C7H7K1
names: Similarity
messages: Belongs to the aldose epimerase family.

1796613:A4V03 RS15035
gene id: 1796613:A4V03_RS15035
uniprot id: A0A1C7H276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS13135
gene id: 1796613:A4V03_RS13135
uniprot id: A0A1C7H454
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1796613:A4V03 RS00660
gene id: 1796613:A4V03_RS00660
uniprot id: A0A1C7GV98
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1796613:A4V03 RS01260
gene id: 1796613:A4V03_RS01260
uniprot id: A0A1C7GVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS18635
gene id: 1796613:A4V03_RS18635
uniprot id: A0A1C7H3R0
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS05495
gene id: 1796613:A4V03_RS05495
uniprot id: A0A1C7GXS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1796613:A4V03 RS16100
gene id: 1796613:A4V03_RS16100
uniprot id: A0A1C7H4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1796613:A4V03 RS08390
gene id: 1796613:A4V03_RS08390
uniprot id: A0A1C7H1X9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS03325
gene id: 1796613:A4V03_RS03325
uniprot id: A0A1C7GY64
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1796613:A4V03 RS10160
gene id: 1796613:A4V03_RS10160
uniprot id: A0A1C7H2S9
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1796613:A4V03 RS00580
gene id: 1796613:A4V03_RS00580
uniprot id: A0A1C7GVJ9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS10315
gene id: 1796613:A4V03_RS10315
uniprot id: A0A1C7H2V4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1796613:A4V03 RS18905
gene id: 1796613:A4V03_RS18905
uniprot id: A0A1C7H3V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS16090
gene id: 1796613:A4V03_RS16090
uniprot id: A0A1C7H2P1
names: Similarity
messages: Belongs to the peptidase S66 family.

1796613:A4V03 RS19945
gene id: 1796613:A4V03_RS19945
uniprot id: A0A1C7H4N9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1796613:A4V03 RS13395
gene id: 1796613:A4V03_RS13395
uniprot id: A0A1C7H485
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1796613:A4V03 RS00130
gene id: 1796613:A4V03_RS00130
uniprot id: A0A1C7GV18
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1796613:A4V03 RS20205
gene id: 1796613:A4V03_RS20205
uniprot id: A0A1C7H3P6
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS09450
gene id: 1796613:A4V03_RS09450
uniprot id: A0A1C7H2G2
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1796613:A4V03 RS02105
gene id: 1796613:A4V03_RS02105
uniprot id: A0A1C7GY83
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1796613:A4V03 RS10445
gene id: 1796613:A4V03_RS10445
uniprot id: A0A1C7GZ69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS16890
gene id: 1796613:A4V03_RS16890
uniprot id: A0A1C7H520
names: Similarity
messages: Belongs to the asparaginase 1 family.

1796613:A4V03 RS19595
gene id: 1796613:A4V03_RS19595
uniprot id: A0A1C7H6B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1796613:A4V03 RS00770
gene id: 1796613:A4V03_RS00770
uniprot id: A0A1C7GVG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1796613:A4V03 RS01060
gene id: 1796613:A4V03_RS01060
uniprot id: A0A1C7GVL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1796613:A4V03 RS12880
gene id: 1796613:A4V03_RS12880
uniprot id: A0A1C7H3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1796613:A4V03 RS07060
gene id: 1796613:A4V03_RS07060
uniprot id: A0A1C7GXP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1796613:A4V03 RS14635
gene id: 1796613:A4V03_RS14635
uniprot id: A0A1C7H1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS00940
gene id: 1796613:A4V03_RS00940
uniprot id: A0A1C7GWZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS01970
gene id: 1796613:A4V03_RS01970
uniprot id: A0A1C7GYR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1796613:A4V03 RS01625
gene id: 1796613:A4V03_RS01625
uniprot id: A0A1C7H6T0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1796613:A4V03 RS20105
gene id: 1796613:A4V03_RS20105
uniprot id: A0A1C7H4R8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS08680
gene id: 1796613:A4V03_RS08680
uniprot id: A0A1C7H1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1796613:A4V03 RS06430
gene id: 1796613:A4V03_RS06430
uniprot id: A0A1C7H113
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1796613:A4V03 RS11365
gene id: 1796613:A4V03_RS11365
uniprot id: A0A1C7H569
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1796613:A4V03 RS18685
gene id: 1796613:A4V03_RS18685
uniprot id: A0A1C7H3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1796613:A4V03 RS10295
gene id: 1796613:A4V03_RS10295
uniprot id: A0A1C7GZQ7
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS02680
gene id: 1796613:A4V03_RS02680
uniprot id: A0A1C7GW80
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS19185
gene id: 1796613:A4V03_RS19185
uniprot id: A0A1C7H5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS08210
gene id: 1796613:A4V03_RS08210
uniprot id: A0A1C7GYU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS05835
gene id: 1796613:A4V03_RS05835
uniprot id: A0A1C7GXV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS12005
gene id: 1796613:A4V03_RS12005
uniprot id: A0A1C7H0K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1796613:A4V03 RS18410
gene id: 1796613:A4V03_RS18410
uniprot id: A0A1C7H3R7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS07235
gene id: 1796613:A4V03_RS07235
uniprot id: A0A1C7GYC9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS14895
gene id: 1796613:A4V03_RS14895
uniprot id: A0A1C7H3V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1796613:A4V03 RS13875
gene id: 1796613:A4V03_RS13875
uniprot id: A0A1C7H3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS18240
gene id: 1796613:A4V03_RS18240
uniprot id: A0A1C7H5E8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1796613:A4V03 RS12035
gene id: 1796613:A4V03_RS12035
uniprot id: A0A1C7H0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1796613:A4V03 RS12545
gene id: 1796613:A4V03_RS12545
uniprot id: A0A1C7H2R2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1796613:A4V03 RS16600
gene id: 1796613:A4V03_RS16600
uniprot id: A0A1V0QDB0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1796613:A4V03 RS11800
gene id: 1796613:A4V03_RS11800
uniprot id: A0A1C7H2U2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1796613:A4V03 RS18895
gene id: 1796613:A4V03_RS18895
uniprot id: A0A1C7H3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1796613:A4V03 RS00675
gene id: 1796613:A4V03_RS00675
uniprot id: A0A1C7GVA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1796613:A4V03 RS00750
gene id: 1796613:A4V03_RS00750
uniprot id: A0A1C7GVM7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1796613:A4V03 RS02740
gene id: 1796613:A4V03_RS02740
uniprot id: A0A1C7GWE3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1796613:A4V03 RS10195
gene id: 1796613:A4V03_RS10195
uniprot id: A0A1C7GZQ5
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS15335
gene id: 1796613:A4V03_RS15335
uniprot id: A0A1C7H1D4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1796613:A4V03 RS19540
gene id: 1796613:A4V03_RS19540
uniprot id: A0A1C7H6A7
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS07285
gene id: 1796613:A4V03_RS07285
uniprot id: A0A1C7GYE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1796613:A4V03 RS10590
gene id: 1796613:A4V03_RS10590
uniprot id: A0A1C7H2A3
names: Similarity
messages: Belongs to the UxaA family.

1796613:A4V03 RS16625
gene id: 1796613:A4V03_RS16625
uniprot id: A0A1C7H1W9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1796613:A4V03 RS16790
gene id: 1796613:A4V03_RS16790
uniprot id: A0A1C7H302
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1796613:A4V03 RS01055
gene id: 1796613:A4V03_RS01055
uniprot id: A0A1C7GXP0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1796613:A4V03 RS10005
gene id: 1796613:A4V03_RS10005
uniprot id: A0A1C7H2Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1796613:A4V03 RS18170
gene id: 1796613:A4V03_RS18170
uniprot id: A0A1C7H384
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1796613:A4V03 RS12540
gene id: 1796613:A4V03_RS12540
uniprot id: A0A1C7H352
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1796613:A4V03 RS06700
gene id: 1796613:A4V03_RS06700
uniprot id: A0A1C7H162
names: Similarity
messages: Belongs to the aldose epimerase family.

1796613:A4V03 RS04080
gene id: 1796613:A4V03_RS04080
uniprot id: A0A1C7H4S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1796613:A4V03 RS14675
gene id: 1796613:A4V03_RS14675
uniprot id: A0A1C7H460
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1796613:A4V03 RS14960
gene id: 1796613:A4V03_RS14960
uniprot id: A0A1C7H5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS09495
gene id: 1796613:A4V03_RS09495
uniprot id: A0A1C7GZG4
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS01395
gene id: 1796613:A4V03_RS01395
uniprot id: A0A1C7GX96
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1796613:A4V03 RS13975
gene id: 1796613:A4V03_RS13975
uniprot id: A0A1C7H0T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

1796613:A4V03 RS01355
gene id: 1796613:A4V03_RS01355
uniprot id: A0A1C7GVX4
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1796613:A4V03 RS09145
gene id: 1796613:A4V03_RS09145
uniprot id: A0A1C7H1J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1796613:A4V03 RS14510
gene id: 1796613:A4V03_RS14510
uniprot id: A0A1C7H3Q1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1796613:A4V03 RS13310
gene id: 1796613:A4V03_RS13310
uniprot id: A0A1C7H346
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1796613:A4V03 RS00700
gene id: 1796613:A4V03_RS00700
uniprot id: A0A1C7GXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1796613:A4V03 RS20080
gene id: 1796613:A4V03_RS20080
uniprot id: A0A1C7H4I6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1796613:A4V03 RS01990
gene id: 1796613:A4V03_RS01990
uniprot id: A0A1C7GXH1
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1796613:A4V03 RS00465
gene id: 1796613:A4V03_RS00465
uniprot id: A0A1C7GXE2
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS14440
gene id: 1796613:A4V03_RS14440
uniprot id: A0A1C7H440
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1796613:A4V03 RS18010
gene id: 1796613:A4V03_RS18010
uniprot id: A0A1C7H3K5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1796613:A4V03 RS19790
gene id: 1796613:A4V03_RS19790
uniprot id: A0A1C7H5P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1796613:A4V03 RS18365
gene id: 1796613:A4V03_RS18365
uniprot id: A0A1C7H7Z0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796613:A4V03 RS01200
gene id: 1796613:A4V03_RS01200
uniprot id: A0A1C7GVJ1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1796613:A4V03 RS01725
gene id: 1796613:A4V03_RS01725
uniprot id: A0A1C7GVS3
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS11470
gene id: 1796613:A4V03_RS11470
uniprot id: A0A1C7H0G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1796613:A4V03 RS08035
gene id: 1796613:A4V03_RS08035
uniprot id: A0A1C7GYP4
names: Similarity
messages: Belongs to the ParB family.

1796613:A4V03 RS17835
gene id: 1796613:A4V03_RS17835
uniprot id: A0A1C7H3B5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1796613:A4V03 RS05200
gene id: 1796613:A4V03_RS05200
uniprot id: A0A1C7GXM0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1796613:A4V03 RS13885
gene id: 1796613:A4V03_RS13885
uniprot id: A0A1C7H3U3
names: Similarity
messages: Belongs to the PstS family.

1796613:A4V03 RS09725
gene id: 1796613:A4V03_RS09725
uniprot id: A0A1C7GZS6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1796613:A4V03 RS10470
gene id: 1796613:A4V03_RS10470
uniprot id: A0A1C7GZT7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796613:A4V03 RS10890
gene id: 1796613:A4V03_RS10890
uniprot id: A0A1C7H5C1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1796613:A4V03 RS13440
gene id: 1796613:A4V03_RS13440
uniprot id: A0A1C7H186
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1796613:A4V03 RS06695
gene id: 1796613:A4V03_RS06695
uniprot id: A0A1C7GZV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1796613:A4V03 RS19615
gene id: 1796613:A4V03_RS19615
uniprot id: A0A1C7H644
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS19600
gene id: 1796613:A4V03_RS19600
uniprot id: A0A1C7H438
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1796613:A4V03 RS12515
gene id: 1796613:A4V03_RS12515
uniprot id: A0A1C7H0S8
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1796613:A4V03 RS07995
gene id: 1796613:A4V03_RS07995
uniprot id: A0A1C7GYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1796613:A4V03 RS18710
gene id: 1796613:A4V03_RS18710
uniprot id: A0A1C7H3Y1
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS00715
gene id: 1796613:A4V03_RS00715
uniprot id: A0A1C7GVF5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1796613:A4V03 RS02315
gene id: 1796613:A4V03_RS02315
uniprot id: A0A1C7GW18
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS10425
gene id: 1796613:A4V03_RS10425
uniprot id: A0A1C7H003
names: Similarity
messages: Belongs to the glutamate synthase family.

1796613:A4V03 RS09425
gene id: 1796613:A4V03_RS09425
uniprot id: A0A1C7H1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1796613:A4V03 RS16865
gene id: 1796613:A4V03_RS16865
uniprot id: A0A1C7H213
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1796613:A4V03 RS04435
gene id: 1796613:A4V03_RS04435
uniprot id: A0A1C7GX31
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS02910
gene id: 1796613:A4V03_RS02910
uniprot id: A0A1C7GWG7
names: Similarity
messages: Belongs to the peptidase C40 family.

1796613:A4V03 RS16580
gene id: 1796613:A4V03_RS16580
uniprot id: A0A1C7H547
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1796613:A4V03 RS06515
gene id: 1796613:A4V03_RS06515
uniprot id: A0A1C7GXY8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796613:A4V03 RS08525
gene id: 1796613:A4V03_RS08525
uniprot id: A0A1C7H200
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1796613:A4V03 RS08530
gene id: 1796613:A4V03_RS08530
uniprot id: A0A1C7GY89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1796613:A4V03 RS01165
gene id: 1796613:A4V03_RS01165
uniprot id: A0A1C7GUW8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1796613:A4V03 RS01330
gene id: 1796613:A4V03_RS01330
uniprot id: A0A1C7GYG7
names: Similarity
messages: Belongs to the CarB family.

1796613:A4V03 RS16725
gene id: 1796613:A4V03_RS16725
uniprot id: A0A1C7H5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1796613:A4V03 RS19120
gene id: 1796613:A4V03_RS19120
uniprot id: A0A1C7H437
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1796613:A4V03 RS11010
gene id: 1796613:A4V03_RS11010
uniprot id: A0A1C7H356
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1796613:A4V03 RS11615
gene id: 1796613:A4V03_RS11615
uniprot id: A0A1C7H0L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS16700
gene id: 1796613:A4V03_RS16700
uniprot id: A0A1C7H4Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1796613:A4V03 RS04765
gene id: 1796613:A4V03_RS04765
uniprot id: A0A1C7GX86
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS18750
gene id: 1796613:A4V03_RS18750
uniprot id: A0A1C7H6S6
names: Similarity
messages: Belongs to the peptidase S13 family.

1796613:A4V03 RS14250
gene id: 1796613:A4V03_RS14250
uniprot id: A0A1C7H1V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1796613:A4V03 RS02850
gene id: 1796613:A4V03_RS02850
uniprot id: A0A1C7H6M9
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS19125
gene id: 1796613:A4V03_RS19125
uniprot id: A0A1C7H3Z0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1796613:A4V03 RS00755
gene id: 1796613:A4V03_RS00755
uniprot id: A0A1C7GXH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1796613:A4V03 RS16780
gene id: 1796613:A4V03_RS16780
uniprot id: A0A1C7H204
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1796613:A4V03 RS18140
gene id: 1796613:A4V03_RS18140
uniprot id: A0A1C7H6I8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1796613:A4V03 RS17300
gene id: 1796613:A4V03_RS17300
uniprot id: A0A1C7H5G1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1796613:A4V03 RS05950
gene id: 1796613:A4V03_RS05950
uniprot id: A0A1C7H7B8
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS07555
gene id: 1796613:A4V03_RS07555
uniprot id: A0A1C7GYH3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1796613:A4V03 RS17855
gene id: 1796613:A4V03_RS17855
uniprot id: A0A1C7H2J1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS14580
gene id: 1796613:A4V03_RS14580
uniprot id: A0A1C7H1P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1796613:A4V03 RS18265
gene id: 1796613:A4V03_RS18265
uniprot id: A0A1C7H2R5
names: Similarity
messages: Belongs to the DprA/Smf family.

1796613:A4V03 RS11045
gene id: 1796613:A4V03_RS11045
uniprot id: A0A1C7H2G3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS16030
gene id: 1796613:A4V03_RS16030
uniprot id: A0A1C7H264
names: Similarity
messages: Belongs to the sigma-54 factor family.

1796613:A4V03 RS12390
gene id: 1796613:A4V03_RS12390
uniprot id: A0A1C7H0N1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1796613:A4V03 RS08795
gene id: 1796613:A4V03_RS08795
uniprot id: A0A1C7GZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1796613:A4V03 RS13860
gene id: 1796613:A4V03_RS13860
uniprot id: A0A1C7H4I3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1796613:A4V03 RS19285
gene id: 1796613:A4V03_RS19285
uniprot id: A0A1C7H3X5
names: Similarity
messages: Belongs to the DapB family.

1796613:A4V03 RS04455
gene id: 1796613:A4V03_RS04455
uniprot id: A0A1C7GZY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1796613:A4V03 RS04425
gene id: 1796613:A4V03_RS04425
uniprot id: A0A1C7GZ87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1796613:A4V03 RS15960
gene id: 1796613:A4V03_RS15960
uniprot id: A0A1C7H5L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1796613:A4V03 RS11920
gene id: 1796613:A4V03_RS11920
uniprot id: A0A1C7H2T9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS10040
gene id: 1796613:A4V03_RS10040
uniprot id: A0A1C7GZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1796613:A4V03 RS20195
gene id: 1796613:A4V03_RS20195
uniprot id: A0A4S2DEB7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1796613:A4V03 RS06785
gene id: 1796613:A4V03_RS06785
uniprot id: A0A1C7GY57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1796613:A4V03 RS20060
gene id: 1796613:A4V03_RS20060
uniprot id: A0A1C7H4M6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS16755
gene id: 1796613:A4V03_RS16755
uniprot id: A0A1C7H2H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1796613:A4V03 RS05920
gene id: 1796613:A4V03_RS05920
uniprot id: A0A1C7H4X3
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS02745
gene id: 1796613:A4V03_RS02745
uniprot id: A0A1C7H4Z3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1796613:A4V03 RS16445
gene id: 1796613:A4V03_RS16445
uniprot id: A0A1C7H780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1796613:A4V03 RS15830
gene id: 1796613:A4V03_RS15830
uniprot id: A0A1C7H5B9
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS15900
gene id: 1796613:A4V03_RS15900
uniprot id: A0A1C7H4M5
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS01155
gene id: 1796613:A4V03_RS01155
uniprot id: A0A1C7GX58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1796613:A4V03 RS11665
gene id: 1796613:A4V03_RS11665
uniprot id: A0A1C7H3F8
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS07165
gene id: 1796613:A4V03_RS07165
uniprot id: A0A1C7H0H0
names: Similarity
messages: Belongs to the FBPase class 3 family.

1796613:A4V03 RS06850
gene id: 1796613:A4V03_RS06850
uniprot id: A0A1C7GZY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1796613:A4V03 RS13580
gene id: 1796613:A4V03_RS13580
uniprot id: A0A1C7H4F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1796613:A4V03 RS05870
gene id: 1796613:A4V03_RS05870
uniprot id: A0A1C7GZF9
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS14095
gene id: 1796613:A4V03_RS14095
uniprot id: A0A1C7H1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1796613:A4V03 RS00655
gene id: 1796613:A4V03_RS00655
uniprot id: A0A1C7GVE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1796613:A4V03 RS13905
gene id: 1796613:A4V03_RS13905
uniprot id: A0A1C7H5L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS07380
gene id: 1796613:A4V03_RS07380
uniprot id: A0A1C7H062
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1796613:A4V03 RS00360
gene id: 1796613:A4V03_RS00360
uniprot id: A0A1C7GVA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS21115
gene id: 1796613:A4V03_RS21115
uniprot id: A0A7T9ALF5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1796613:A4V03 RS11005
gene id: 1796613:A4V03_RS11005
uniprot id: A0A1C7H1X5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS14350
gene id: 1796613:A4V03_RS14350
uniprot id: A0A1C7H3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS02880
gene id: 1796613:A4V03_RS02880
uniprot id: A0A1C7GZ75
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1796613:A4V03 RS11315
gene id: 1796613:A4V03_RS11315
uniprot id: A0A1C7H0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1796613:A4V03 RS16585
gene id: 1796613:A4V03_RS16585
uniprot id: A0A1C7H4M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1796613:A4V03 RS04780
gene id: 1796613:A4V03_RS04780
uniprot id: A0A1C7H041
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1796613:A4V03 RS19835
gene id: 1796613:A4V03_RS19835
uniprot id: A0A1C7H838
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1796613:A4V03 RS19830
gene id: 1796613:A4V03_RS19830
uniprot id: A0A1C7H4M1
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS13405
gene id: 1796613:A4V03_RS13405
uniprot id: A0A1C7H1G5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS02125
gene id: 1796613:A4V03_RS02125
uniprot id: A0A1C7GW39
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS17260
gene id: 1796613:A4V03_RS17260
uniprot id: A0A1C7H578
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS07250
gene id: 1796613:A4V03_RS07250
uniprot id: A0A1C7H1F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1796613:A4V03 RS10235
gene id: 1796613:A4V03_RS10235
uniprot id: A0A1C7H1G1
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS11390
gene id: 1796613:A4V03_RS11390
uniprot id: A0A1C7H071
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1796613:A4V03 RS12695
gene id: 1796613:A4V03_RS12695
uniprot id: A0A1C7H2U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1796613:A4V03 RS17265
gene id: 1796613:A4V03_RS17265
uniprot id: A0A1C7H2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS02515
gene id: 1796613:A4V03_RS02515
uniprot id: A0A1C7GYA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1796613:A4V03 RS03135
gene id: 1796613:A4V03_RS03135
uniprot id: A0A1C7GZD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1796613:A4V03 RS17105
gene id: 1796613:A4V03_RS17105
uniprot id: A0A1C7H340
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1796613:A4V03 RS01195
gene id: 1796613:A4V03_RS01195
uniprot id: A0A1C7GVI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1796613:A4V03 RS17200
gene id: 1796613:A4V03_RS17200
uniprot id: A0A1C7H5E2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1796613:A4V03 RS09210
gene id: 1796613:A4V03_RS09210
uniprot id: A0A1C7H1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1796613:A4V03 RS09380
gene id: 1796613:A4V03_RS09380
uniprot id: A0A1C7GZ97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS19180
gene id: 1796613:A4V03_RS19180
uniprot id: A0A1C7H400
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS02535
gene id: 1796613:A4V03_RS02535
uniprot id: A0A1C7GXZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1796613:A4V03 RS07360
gene id: 1796613:A4V03_RS07360
uniprot id: A0A1C7GYF2
names: Similarity
messages: Belongs to the peptidase C1 family.

1796613:A4V03 RS04470
gene id: 1796613:A4V03_RS04470
uniprot id: A0A1C7GXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1796613:A4V03 RS17365
gene id: 1796613:A4V03_RS17365
uniprot id: A0A1C7H595
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1796613:A4V03 RS02170
gene id: 1796613:A4V03_RS02170
uniprot id: A0A1C7H6T6
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS15295
gene id: 1796613:A4V03_RS15295
uniprot id: A0A1C7H493
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS17325
gene id: 1796613:A4V03_RS17325
uniprot id: A0A1C7H326
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS20030
gene id: 1796613:A4V03_RS20030
uniprot id: A0A1C7H4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS07800
gene id: 1796613:A4V03_RS07800
uniprot id: A0A1C7H0D6
names: Similarity
messages: Belongs to the ParB family.

1796613:A4V03 RS17295
gene id: 1796613:A4V03_RS17295
uniprot id: A0A1C7H382
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1796613:A4V03 RS14355
gene id: 1796613:A4V03_RS14355
uniprot id: A0A1C7H4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1796613:A4V03 RS13185
gene id: 1796613:A4V03_RS13185
uniprot id: A0A1C7H323
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

1796613:A4V03 RS19785
gene id: 1796613:A4V03_RS19785
uniprot id: A0A1C7H669
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1796613:A4V03 RS15005
gene id: 1796613:A4V03_RS15005
uniprot id: A0A1C7H492
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS11515
gene id: 1796613:A4V03_RS11515
uniprot id: A0A1C7H0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1796613:A4V03 RS04505
gene id: 1796613:A4V03_RS04505
uniprot id: A0A1C7GX44
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796613:A4V03 RS16680
gene id: 1796613:A4V03_RS16680
uniprot id: A0A1C7H1Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1796613:A4V03 RS07420
gene id: 1796613:A4V03_RS07420
uniprot id: A0A1C7GYF0
names: Similarity
messages: Belongs to the IMPACT family.

1796613:A4V03 RS18855
gene id: 1796613:A4V03_RS18855
uniprot id: A0A1C7H6T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1796613:A4V03 RS19360
gene id: 1796613:A4V03_RS19360
uniprot id: A0A1C7H773
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS06870
gene id: 1796613:A4V03_RS06870
uniprot id: A0A1C7GYG2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1796613:A4V03 RS01080
gene id: 1796613:A4V03_RS01080
uniprot id: A0A1C7GYD1
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS09500
gene id: 1796613:A4V03_RS09500
uniprot id: A0A1C7H170
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1796613:A4V03 RS14920
gene id: 1796613:A4V03_RS14920
uniprot id: A0A1C7H488
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1796613:A4V03 RS13140
gene id: 1796613:A4V03_RS13140
uniprot id: A0A1C7H596
names: Similarity
messages: Belongs to the Fur family.

1796613:A4V03 RS07530
gene id: 1796613:A4V03_RS07530
uniprot id: A0A1C7H0T0
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS17820
gene id: 1796613:A4V03_RS17820
uniprot id: A0A1C7H5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1796613:A4V03 RS01555
gene id: 1796613:A4V03_RS01555
uniprot id: A0A1C7GVP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS06880
gene id: 1796613:A4V03_RS06880
uniprot id: A0A1C7GZX5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

1796613:A4V03 RS17990
gene id: 1796613:A4V03_RS17990
uniprot id: A0A1C7H5L1
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

1796613:A4V03 RS06085
gene id: 1796613:A4V03_RS06085
uniprot id: A0A1C7GXS1
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1796613:A4V03 RS09535
gene id: 1796613:A4V03_RS09535
uniprot id: A0A1C7GZC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS18000
gene id: 1796613:A4V03_RS18000
uniprot id: A0A1C7H5K4
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1796613:A4V03 RS04460
gene id: 1796613:A4V03_RS04460
uniprot id: A0A1C7H7X3
names: Subcellular Location Annotation
messages: Nucleus

1796613:A4V03 RS19155
gene id: 1796613:A4V03_RS19155
uniprot id: A0A1C7H660
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1796613:A4V03 RS13845
gene id: 1796613:A4V03_RS13845
uniprot id: A0A1C7H1M1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1796613:A4V03 RS05815
gene id: 1796613:A4V03_RS05815
uniprot id: A0A1C7GXP3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1796613:A4V03 RS18215
gene id: 1796613:A4V03_RS18215
uniprot id: A0A1C7H5N7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1796613:A4V03 RS09590
gene id: 1796613:A4V03_RS09590
uniprot id: A0A1C7H2I4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS13160
gene id: 1796613:A4V03_RS13160
uniprot id: A0A1C7H327
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1796613:A4V03 RS12905
gene id: 1796613:A4V03_RS12905
uniprot id: A0A1C7H0Z2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1796613:A4V03 RS03150
gene id: 1796613:A4V03_RS03150
uniprot id: A0A1C7GYQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1796613:A4V03 RS00735
gene id: 1796613:A4V03_RS00735
uniprot id: A0A1C7GWY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1796613:A4V03 RS07040
gene id: 1796613:A4V03_RS07040
uniprot id: A0A1C7GY65
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1796613:A4V03 RS02590
gene id: 1796613:A4V03_RS02590
uniprot id: A0A1C7GZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1796613:A4V03 RS12825
gene id: 1796613:A4V03_RS12825
uniprot id: A0A1C7H3A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS20050
gene id: 1796613:A4V03_RS20050
uniprot id: A0A1C7H4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1796613:A4V03 RS12970
gene id: 1796613:A4V03_RS12970
uniprot id: A0A1C7H2Y8
names: Similarity
messages: Belongs to the peptidase C1 family.

1796613:A4V03 RS01420
gene id: 1796613:A4V03_RS01420
uniprot id: A0A1C7GXV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS06655
gene id: 1796613:A4V03_RS06655
uniprot id: A0A1C7GXH4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1796613:A4V03 RS14555
gene id: 1796613:A4V03_RS14555
uniprot id: A0A1C7H209
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1796613:A4V03 RS14600
gene id: 1796613:A4V03_RS14600
uniprot id: A0A1C7H4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS01360
gene id: 1796613:A4V03_RS01360
uniprot id: A0A1C7GXU3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1796613:A4V03 RS19480
gene id: 1796613:A4V03_RS19480
uniprot id: A0A1C7H6B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796613:A4V03 RS02035
gene id: 1796613:A4V03_RS02035
uniprot id: A0A1C7GVB0
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS19220
gene id: 1796613:A4V03_RS19220
uniprot id: A0A1C7H3W7
names: Similarity
messages: Belongs to the LOG family.

1796613:A4V03 RS02615
gene id: 1796613:A4V03_RS02615
uniprot id: A0A1C7H4P9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1796613:A4V03 RS00705
gene id: 1796613:A4V03_RS00705
uniprot id: A0A1C7GWV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS13660
gene id: 1796613:A4V03_RS13660
uniprot id: A0A1C7H188
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1796613:A4V03 RS06570
gene id: 1796613:A4V03_RS06570
uniprot id: A0A1C7H078
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1796613:A4V03 RS16765
gene id: 1796613:A4V03_RS16765
uniprot id: A0A1C7H2T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1796613:A4V03 RS04490
gene id: 1796613:A4V03_RS04490
uniprot id: A0A1C7GZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1796613:A4V03 RS09615
gene id: 1796613:A4V03_RS09615
uniprot id: A0A1C7H148
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS04385
gene id: 1796613:A4V03_RS04385
uniprot id: A0A1C7GX20
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1796613:A4V03 RS11075
gene id: 1796613:A4V03_RS11075
uniprot id: A0A1C7GZH1
names: Similarity
messages: Belongs to the Dps family.

1796613:A4V03 RS04715
gene id: 1796613:A4V03_RS04715
uniprot id: A0A1C7H029
names: Similarity
messages: Belongs to the Vsr family.

1796613:A4V03 RS01640
gene id: 1796613:A4V03_RS01640
uniprot id: A0A1C7GW20
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796613:A4V03 RS20485
gene id: 1796613:A4V03_RS20485
uniprot id: A0A1C7H4K1
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1796613:A4V03 RS13410
gene id: 1796613:A4V03_RS13410
uniprot id: A0A1C7H3J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1796613:A4V03 RS08860
gene id: 1796613:A4V03_RS08860
uniprot id: A0A1C7GZ27
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS18575
gene id: 1796613:A4V03_RS18575
uniprot id: A0A1C7H3P9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS03070
gene id: 1796613:A4V03_RS03070
uniprot id: A0A1C7GWE8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796613:A4V03 RS18285
gene id: 1796613:A4V03_RS18285
uniprot id: A0A1C7H5P5
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS11785
gene id: 1796613:A4V03_RS11785
uniprot id: A0A1C7H2R7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS12530
gene id: 1796613:A4V03_RS12530
uniprot id: A0A1C7H058
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS16440
gene id: 1796613:A4V03_RS16440
uniprot id: A0A1C7H4F6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1796613:A4V03 RS07405
gene id: 1796613:A4V03_RS07405
uniprot id: A0A1C7H055
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS18315
gene id: 1796613:A4V03_RS18315
uniprot id: A0A1C7H2S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS01950
gene id: 1796613:A4V03_RS01950
uniprot id: A0A1C7GVW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1796613:A4V03 RS10515
gene id: 1796613:A4V03_RS10515
uniprot id: A0A1C7H252
names: Similarity
messages: Belongs to the TrpF family.

1796613:A4V03 RS13840
gene id: 1796613:A4V03_RS13840
uniprot id: A0A1C7H585
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS18875
gene id: 1796613:A4V03_RS18875
uniprot id: A0A1C7H8M6
names: Similarity
messages: Belongs to the LOG family.

1796613:A4V03 RS11500
gene id: 1796613:A4V03_RS11500
uniprot id: A0A1C7GZP0
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1796613:A4V03 RS03250
gene id: 1796613:A4V03_RS03250
uniprot id: A0A1C7GYR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS18755
gene id: 1796613:A4V03_RS18755
uniprot id: A0A1C7H2Z4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1796613:A4V03 RS03045
gene id: 1796613:A4V03_RS03045
uniprot id: A0A1C7GWP7
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS11900
gene id: 1796613:A4V03_RS11900
uniprot id: A0A1C7H7P0
names: Similarity
messages: Belongs to the peptidase C69 family.

1796613:A4V03 RS01930
gene id: 1796613:A4V03_RS01930
uniprot id: A0A1C7GXG2
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1796613:A4V03 RS16640
gene id: 1796613:A4V03_RS16640
uniprot id: A0A1C7H4N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1796613:A4V03 RS11555
gene id: 1796613:A4V03_RS11555
uniprot id: A0A1C7H3E1
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1796613:A4V03 RS16750
gene id: 1796613:A4V03_RS16750
uniprot id: A0A1C7H502
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1796613:A4V03 RS06790
gene id: 1796613:A4V03_RS06790
uniprot id: A0A1C7GY42
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS06665
gene id: 1796613:A4V03_RS06665
uniprot id: A0A1C7H0A8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1796613:A4V03 RS00225
gene id: 1796613:A4V03_RS00225
uniprot id: A0A1C7GVD8
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS06035
gene id: 1796613:A4V03_RS06035
uniprot id: A0A1C7H710
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1796613:A4V03 RS13945
gene id: 1796613:A4V03_RS13945
uniprot id: A0A1C7H3F6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1796613:A4V03 RS14665
gene id: 1796613:A4V03_RS14665
uniprot id: A0A1C7H244
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1796613:A4V03 RS13320
gene id: 1796613:A4V03_RS13320
uniprot id: A0A1C7H134
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1796613:A4V03 RS19095
gene id: 1796613:A4V03_RS19095
uniprot id: A0A1C7H451
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1796613:A4V03 RS13290
gene id: 1796613:A4V03_RS13290
uniprot id: A0A1C7H7R7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1796613:A4V03 RS18845
gene id: 1796613:A4V03_RS18845
uniprot id: A0A1C7H3U5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS10000
gene id: 1796613:A4V03_RS10000
uniprot id: A0A1C7H1G0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1796613:A4V03 RS07225
gene id: 1796613:A4V03_RS07225
uniprot id: A0A1C7GYD2
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS07545
gene id: 1796613:A4V03_RS07545
uniprot id: A0A1C7GYI4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1796613:A4V03 RS16720
gene id: 1796613:A4V03_RS16720
uniprot id: A0A1C7H4N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1796613:A4V03 RS09440
gene id: 1796613:A4V03_RS09440
uniprot id: A0A1C7GZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1796613:A4V03 RS12420
gene id: 1796613:A4V03_RS12420
uniprot id: A0A1C7H8B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1796613:A4V03 RS19605
gene id: 1796613:A4V03_RS19605
uniprot id: A0A1C7H4F8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1796613:A4V03 RS11930
gene id: 1796613:A4V03_RS11930
uniprot id: A0A1C7H2W3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1796613:A4V03 RS18915
gene id: 1796613:A4V03_RS18915
uniprot id: A0A1C7H5R1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1796613:A4V03 RS18715
gene id: 1796613:A4V03_RS18715
uniprot id: A0A1C7H6B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS11385
gene id: 1796613:A4V03_RS11385
uniprot id: A0A1C7H2M5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1796613:A4V03 RS06040
gene id: 1796613:A4V03_RS06040
uniprot id: A0A1C7GZJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS07045
gene id: 1796613:A4V03_RS07045
uniprot id: A0A1C7GYA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1796613:A4V03 RS09530
gene id: 1796613:A4V03_RS09530
uniprot id: A0A1C7H1R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1796613:A4V03 RS10125
gene id: 1796613:A4V03_RS10125
uniprot id: A0A1C7H226
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Fimbrium
messages: Membrane

1796613:A4V03 RS07385
gene id: 1796613:A4V03_RS07385
uniprot id: A0A1C7H1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1796613:A4V03 RS06280
gene id: 1796613:A4V03_RS06280
uniprot id: A0A7T8WSI2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1796613:A4V03 RS07370
gene id: 1796613:A4V03_RS07370
uniprot id: A0A1C7GYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1796613:A4V03 RS00120
gene id: 1796613:A4V03_RS00120
uniprot id: A0A1C7H4V2
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS12785
gene id: 1796613:A4V03_RS12785
uniprot id: A0A1C7H2V5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS01400
gene id: 1796613:A4V03_RS01400
uniprot id: A0A1C7GYH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1796613:A4V03 RS08690
gene id: 1796613:A4V03_RS08690
uniprot id: A0A1C7GZ00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1796613:A4V03 RS06580
gene id: 1796613:A4V03_RS06580
uniprot id: A0A1C7GY01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1796613:A4V03 RS19820
gene id: 1796613:A4V03_RS19820
uniprot id: A0A1C7H6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1796613:A4V03 RS19415
gene id: 1796613:A4V03_RS19415
uniprot id: A0A1C7H4A5
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1796613:A4V03 RS15310
gene id: 1796613:A4V03_RS15310
uniprot id: A0A1C7H1Z8
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS06855
gene id: 1796613:A4V03_RS06855
uniprot id: A0A1C7H193
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1796613:A4V03 RS07480
gene id: 1796613:A4V03_RS07480
uniprot id: A0A1C7GYG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1796613:A4V03 RS19815
gene id: 1796613:A4V03_RS19815
uniprot id: A0A1C7H6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1796613:A4V03 RS15895
gene id: 1796613:A4V03_RS15895
uniprot id: A0A1C7H4F2
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS18485
gene id: 1796613:A4V03_RS18485
uniprot id: A0A1C7H3U9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS01665
gene id: 1796613:A4V03_RS01665
uniprot id: A0A1C7H4M8
names: Similarity
messages: Belongs to the RecJ family.

1796613:A4V03 RS02940
gene id: 1796613:A4V03_RS02940
uniprot id: A0A1C7GWN1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796613:A4V03 RS09645
gene id: 1796613:A4V03_RS09645
uniprot id: A0A1C7GZA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1796613:A4V03 RS14225
gene id: 1796613:A4V03_RS14225
uniprot id: A0A1C7H1T5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1796613:A4V03 RS13715
gene id: 1796613:A4V03_RS13715
uniprot id: A0A1C7H1K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1796613:A4V03 RS02085
gene id: 1796613:A4V03_RS02085
uniprot id: A0A1C7GYU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS06760
gene id: 1796613:A4V03_RS06760
uniprot id: A0A1C7GYD9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1796613:A4V03 RS11985
gene id: 1796613:A4V03_RS11985
uniprot id: A0A1C7H7F0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS03400
gene id: 1796613:A4V03_RS03400
uniprot id: A0A1C7GWL6
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS08625
gene id: 1796613:A4V03_RS08625
uniprot id: A0A1C7GZ28
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1796613:A4V03 RS03935
gene id: 1796613:A4V03_RS03935
uniprot id: A0A1C7GWW1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1796613:A4V03 RS19545
gene id: 1796613:A4V03_RS19545
uniprot id: A0A1C7H429
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1796613:A4V03 RS09490
gene id: 1796613:A4V03_RS09490
uniprot id: A0A1C7GZD8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1796613:A4V03 RS20035
gene id: 1796613:A4V03_RS20035
uniprot id: A0A1C7H6Y9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS19930
gene id: 1796613:A4V03_RS19930
uniprot id: A0A1C7H6I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1796613:A4V03 RS10075
gene id: 1796613:A4V03_RS10075
uniprot id: A0A1C7H1D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796613:A4V03 RS12765
gene id: 1796613:A4V03_RS12765
uniprot id: A0A1C7H3Z1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1796613:A4V03 RS06680
gene id: 1796613:A4V03_RS06680
uniprot id: A0A1C7GY43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1796613:A4V03 RS10825
gene id: 1796613:A4V03_RS10825
uniprot id: A0A1C7H1V5
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

1796613:A4V03 RS14925
gene id: 1796613:A4V03_RS14925
uniprot id: A0A1C7H427
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1796613:A4V03 RS04735
gene id: 1796613:A4V03_RS04735
uniprot id: A0A1C7GZF1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1796613:A4V03 RS15160
gene id: 1796613:A4V03_RS15160
uniprot id: A0A1C7H4C2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS13640
gene id: 1796613:A4V03_RS13640
uniprot id: A0A1C7H3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1796613:A4V03 RS17145
gene id: 1796613:A4V03_RS17145
uniprot id: A0A1C7H517
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796613:A4V03 RS03225
gene id: 1796613:A4V03_RS03225
uniprot id: A0A1C7GWH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1796613:A4V03 RS16115
gene id: 1796613:A4V03_RS16115
uniprot id: A0A1C7H4M2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1796613:A4V03 RS12380
gene id: 1796613:A4V03_RS12380
uniprot id: A0A1C7H2N4
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796613:A4V03 RS12750
gene id: 1796613:A4V03_RS12750
uniprot id: A0A1C7H132
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1796613:A4V03 RS18730
gene id: 1796613:A4V03_RS18730
uniprot id: A0A1C7H3H5
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1796613:A4V03 RS01695
gene id: 1796613:A4V03_RS01695
uniprot id: A0A1C7GV50
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS02565
gene id: 1796613:A4V03_RS02565
uniprot id: A0A1C7GYB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1796613:A4V03 RS06055
gene id: 1796613:A4V03_RS06055
uniprot id: A0A1C7H4V9
names: Similarity
messages: Belongs to the Fur family.

1796613:A4V03 RS07195
gene id: 1796613:A4V03_RS07195
uniprot id: A0A1C7H1E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1796613:A4V03 RS13390
gene id: 1796613:A4V03_RS13390
uniprot id: A0A1C7H354
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS12850
gene id: 1796613:A4V03_RS12850
uniprot id: A0A1C7H0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1796613:A4V03 RS00355
gene id: 1796613:A4V03_RS00355
uniprot id: A0A1C7GXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS01465
gene id: 1796613:A4V03_RS01465
uniprot id: A0A1C7GVY9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS18465
gene id: 1796613:A4V03_RS18465
uniprot id: A0A1C7H3N0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS13645
gene id: 1796613:A4V03_RS13645
uniprot id: A0A1C7H3A7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796613:A4V03 RS10785
gene id: 1796613:A4V03_RS10785
uniprot id: A0A1C7H0A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1796613:A4V03 RS10290
gene id: 1796613:A4V03_RS10290
uniprot id: A0A1C7H250
names: Similarity
messages: Belongs to the peptidase S9C family.

1796613:A4V03 RS19010
gene id: 1796613:A4V03_RS19010
uniprot id: A0A1C7H3M5
names: Similarity
messages: Belongs to the GARS family.

1796613:A4V03 RS08415
gene id: 1796613:A4V03_RS08415
uniprot id: A0A1C7H0K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1796613:A4V03 RS12525
gene id: 1796613:A4V03_RS12525
uniprot id: A0A1C7H3V6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1796613:A4V03 RS16825
gene id: 1796613:A4V03_RS16825
uniprot id: A0A1C7H4R6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1796613:A4V03 RS01455
gene id: 1796613:A4V03_RS01455
uniprot id: A0A1C7GYI1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1796613:A4V03 RS11990
gene id: 1796613:A4V03_RS11990
uniprot id: A0A1C7H2Y1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1796613:A4V03 RS02045
gene id: 1796613:A4V03_RS02045
uniprot id: A0A1C7GY78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796613:A4V03 RS00520
gene id: 1796613:A4V03_RS00520
uniprot id: A0A1C7GWS6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1796613:A4V03 RS20160
gene id: 1796613:A4V03_RS20160
uniprot id: A0A1C7H4H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS10275
gene id: 1796613:A4V03_RS10275
uniprot id: A0A1C7H021
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS02700
gene id: 1796613:A4V03_RS02700
uniprot id: A0A1C7GW94
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1796613:A4V03 RS02205
gene id: 1796613:A4V03_RS02205
uniprot id: A0A1C7GW00
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1796613:A4V03 RS01065
gene id: 1796613:A4V03_RS01065
uniprot id: A0A1C7GVH0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1796613:A4V03 RS02825
gene id: 1796613:A4V03_RS02825
uniprot id: A0A3A9BP14
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1796613:A4V03 RS13070
gene id: 1796613:A4V03_RS13070
uniprot id: A0A1C7H189
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1796613:A4V03 RS19135
gene id: 1796613:A4V03_RS19135
uniprot id: A0A1C7H6Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1796613:A4V03 RS18095
gene id: 1796613:A4V03_RS18095
uniprot id: A0A1C7H5V1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1796613:A4V03 RS18765
gene id: 1796613:A4V03_RS18765
uniprot id: A0A1C7H6C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1796613:A4V03 RS02040
gene id: 1796613:A4V03_RS02040
uniprot id: A0A1C7GW93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796613:A4V03 RS10255
gene id: 1796613:A4V03_RS10255
uniprot id: A0A1C7GZT8
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS05705
gene id: 1796613:A4V03_RS05705
uniprot id: A0A1C7H0N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1796613:A4V03 RS13015
gene id: 1796613:A4V03_RS13015
uniprot id: A0A1C7H180
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1796613:A4V03 RS11080
gene id: 1796613:A4V03_RS11080
uniprot id: A0A1C7H0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1796613:A4V03 RS13685
gene id: 1796613:A4V03_RS13685
uniprot id: A0A1C7H0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS03000
gene id: 1796613:A4V03_RS03000
uniprot id: A0A1C7GYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1796613:A4V03 RS19775
gene id: 1796613:A4V03_RS19775
uniprot id: A0A1C7H4L2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1796613:A4V03 RS02000
gene id: 1796613:A4V03_RS02000
uniprot id: A0A1C7GW24
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1796613:A4V03 RS19145
gene id: 1796613:A4V03_RS19145
uniprot id: A0A1C7H462
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS19840
gene id: 1796613:A4V03_RS19840
uniprot id: A0A1C7H4G4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1796613:A4V03 RS11880
gene id: 1796613:A4V03_RS11880
uniprot id: A0A1C7H4D8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1796613:A4V03 RS02580
gene id: 1796613:A4V03_RS02580
uniprot id: A0A1C7GW75
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1796613:A4V03 RS19275
gene id: 1796613:A4V03_RS19275
uniprot id: A0A1C7H678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1796613:A4V03 RS17985
gene id: 1796613:A4V03_RS17985
uniprot id: A0A1C7H5T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS04570
gene id: 1796613:A4V03_RS04570
uniprot id: A0A1C7GX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1796613:A4V03 RS19440
gene id: 1796613:A4V03_RS19440
uniprot id: A0A1C7H4A1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796613:A4V03 RS08540
gene id: 1796613:A4V03_RS08540
uniprot id: A0A1C7H1B2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1796613:A4V03 RS15025
gene id: 1796613:A4V03_RS15025
uniprot id: A0A1C7H4A7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796613:A4V03 RS00170
gene id: 1796613:A4V03_RS00170
uniprot id: A0A1C7GWL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS17935
gene id: 1796613:A4V03_RS17935
uniprot id: A0A1C7H5J3
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS18280
gene id: 1796613:A4V03_RS18280
uniprot id: A0A1C7H5Q9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1796613:A4V03 RS19995
gene id: 1796613:A4V03_RS19995
uniprot id: A0A1C7H4C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1796613:A4V03 RS13575
gene id: 1796613:A4V03_RS13575
uniprot id: A0A1C7H1K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1796613:A4V03 RS05725
gene id: 1796613:A4V03_RS05725
uniprot id: A0A1C7GZC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1796613:A4V03 RS14135
gene id: 1796613:A4V03_RS14135
uniprot id: A0A1C7H4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1796613:A4V03 RS17815
gene id: 1796613:A4V03_RS17815
uniprot id: A0A1C7H5I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1796613:A4V03 RS03330
gene id: 1796613:A4V03_RS03330
uniprot id: A0A1C7GYS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1796613:A4V03 RS14940
gene id: 1796613:A4V03_RS14940
uniprot id: A0A1C7H497
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1796613:A4V03 RS16095
gene id: 1796613:A4V03_RS16095
uniprot id: A0A1C7H2I1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1796613:A4V03 RS00820
gene id: 1796613:A4V03_RS00820
uniprot id: A0A1C7GXH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1796613:A4V03 RS17310
gene id: 1796613:A4V03_RS17310
uniprot id: A0A1C7H588
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS11195
gene id: 1796613:A4V03_RS11195
uniprot id: A0A1C7H0F8
names: Similarity
messages: Belongs to the RutC family.

1796613:A4V03 RS03470
gene id: 1796613:A4V03_RS03470
uniprot id: A0A1C7GYC6
names: Similarity
messages: Belongs to the ArsC family.

1796613:A4V03 RS20520
gene id: 1796613:A4V03_RS20520
uniprot id: A0A1C7H7N7
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS12395
gene id: 1796613:A4V03_RS12395
uniprot id: A0A1C7H0X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1796613:A4V03 RS18585
gene id: 1796613:A4V03_RS18585
uniprot id: A0A1C7H5Q3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1796613:A4V03 RS15135
gene id: 1796613:A4V03_RS15135
uniprot id: A0A1C7H3X8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS11695
gene id: 1796613:A4V03_RS11695
uniprot id: A0A1C7H0C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1796613:A4V03 RS20515
gene id: 1796613:A4V03_RS20515
uniprot id: A0A1C7H4T8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1796613:A4V03 RS00695
gene id: 1796613:A4V03_RS00695
uniprot id: A0A1C7GVL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1796613:A4V03 RS01540
gene id: 1796613:A4V03_RS01540
uniprot id: A0A1C7GX98
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1796613:A4V03 RS18385
gene id: 1796613:A4V03_RS18385
uniprot id: A0A1C7H5G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS14855
gene id: 1796613:A4V03_RS14855
uniprot id: A0A1C7H7V2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1796613:A4V03 RS02135
gene id: 1796613:A4V03_RS02135
uniprot id: A0A1C7GW07
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS08670
gene id: 1796613:A4V03_RS08670
uniprot id: A0A1C7H1D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1796613:A4V03 RS12535
gene id: 1796613:A4V03_RS12535
uniprot id: A0A1C7H121
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796613:A4V03 RS06825
gene id: 1796613:A4V03_RS06825
uniprot id: A0A1C7GZW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1796613:A4V03 RS02275
gene id: 1796613:A4V03_RS02275
uniprot id: A0A1C7GYW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796613:A4V03 RS00405
gene id: 1796613:A4V03_RS00405
uniprot id: A0A1C7GWQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1796613:A4V03 RS14270
gene id: 1796613:A4V03_RS14270
uniprot id: A0A1C7H1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS18270
gene id: 1796613:A4V03_RS18270
uniprot id: A0A1C7H3S0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1796613:A4V03 RS09995
gene id: 1796613:A4V03_RS09995
uniprot id: A0A1C7GZN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1796613:A4V03 RS02495
gene id: 1796613:A4V03_RS02495
uniprot id: A0A1C7GWF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS15125
gene id: 1796613:A4V03_RS15125
uniprot id: A0A1C7H286
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1796613:A4V03 RS06730
gene id: 1796613:A4V03_RS06730
uniprot id: A0A1C7GY54
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796613:A4V03 RS13170
gene id: 1796613:A4V03_RS13170
uniprot id: A0A1C7H114
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1796613:A4V03 RS00850
gene id: 1796613:A4V03_RS00850
uniprot id: A0A1C7GX00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

1796613:A4V03 RS00975
gene id: 1796613:A4V03_RS00975
uniprot id: A0A1C7GX22
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1796613:A4V03 RS12770
gene id: 1796613:A4V03_RS12770
uniprot id: A0A1C7H096
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796613:A4V03 RS11915
gene id: 1796613:A4V03_RS11915
uniprot id: A0A1C7H0R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1796613:A4V03 RS09365
gene id: 1796613:A4V03_RS09365
uniprot id: A0A1C7H1P5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1796613:A4V03 RS04845
gene id: 1796613:A4V03_RS04845
uniprot id: A0A1C7H6Q9
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS17100
gene id: 1796613:A4V03_RS17100
uniprot id: A0A1C7H2M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1796613:A4V03 RS15195
gene id: 1796613:A4V03_RS15195
uniprot id: A0A1C7H3Y9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1796613:A4V03 RS02645
gene id: 1796613:A4V03_RS02645
uniprot id: A0A1C7GZ41
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1796613:A4V03 RS01310
gene id: 1796613:A4V03_RS01310
uniprot id: A0A1C7GVK3
names: Similarity
messages: Belongs to the peptidase M16 family.

1796613:A4V03 RS13005
gene id: 1796613:A4V03_RS13005
uniprot id: A0A1C7H3F4
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1796613:A4V03 RS01365
gene id: 1796613:A4V03_RS01365
uniprot id: A0A1C7GX62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS01975
gene id: 1796613:A4V03_RS01975
uniprot id: A0A1C7GVA1
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS12735
gene id: 1796613:A4V03_RS12735
uniprot id: A0A1C7H2U8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1796613:A4V03 RS02885
gene id: 1796613:A4V03_RS02885
uniprot id: A0A1C7GVP5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1796613:A4V03 RS04265
gene id: 1796613:A4V03_RS04265
uniprot id: A0A1C7GYS9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796613:A4V03 RS01560
gene id: 1796613:A4V03_RS01560
uniprot id: A0A1C7GVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1796613:A4V03 RS08495
gene id: 1796613:A4V03_RS08495
uniprot id: A0A1C7H191
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS03370
gene id: 1796613:A4V03_RS03370
uniprot id: A0A1C7GWV2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1796613:A4V03 RS00215
gene id: 1796613:A4V03_RS00215
uniprot id: A0A1C7GXV0
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS18890
gene id: 1796613:A4V03_RS18890
uniprot id: A0A1C7H4R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1796613:A4V03 RS16715
gene id: 1796613:A4V03_RS16715
uniprot id: A0A1C7H2S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1796613:A4V03 RS01680
gene id: 1796613:A4V03_RS01680
uniprot id: A0A1C7GVS1
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS08350
gene id: 1796613:A4V03_RS08350
uniprot id: A0A1C7H178
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS15000
gene id: 1796613:A4V03_RS15000
uniprot id: A0A1C7H290
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1796613:A4V03 RS09385
gene id: 1796613:A4V03_RS09385
uniprot id: A0A1C7GZC5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1796613:A4V03 RS03255
gene id: 1796613:A4V03_RS03255
uniprot id: A0A1C7GY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1796613:A4V03 RS13110
gene id: 1796613:A4V03_RS13110
uniprot id: A0A1C7H3H3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1796613:A4V03 RS16135
gene id: 1796613:A4V03_RS16135
uniprot id: A0A1C7H4I8
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1796613:A4V03 RS19500
gene id: 1796613:A4V03_RS19500
uniprot id: A0A1C7H463
names: Similarity
messages: Belongs to the SusD family.

1796613:A4V03 RS06025
gene id: 1796613:A4V03_RS06025
uniprot id: A0A1C7GXR5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1796613:A4V03 RS11175
gene id: 1796613:A4V03_RS11175
uniprot id: A0A1C7H068
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1796613:A4V03 RS18505
gene id: 1796613:A4V03_RS18505
uniprot id: A0A1C7H3D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1796613:A4V03 RS16080
gene id: 1796613:A4V03_RS16080
uniprot id: A0A1C7H4Q6
names: Similarity
messages: Belongs to the SufE family.

1796613:A4V03 RS11455
gene id: 1796613:A4V03_RS11455
uniprot id: A0A1C7H2N6
names: Subcellular Location Annotation
messages: Membrane

1796613:A4V03 RS07160
gene id: 1796613:A4V03_RS07160
uniprot id: A0A1C7H014
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1796613:A4V03 RS14560
gene id: 1796613:A4V03_RS14560
uniprot id: A0A1C7H441
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.