1778540:CVE23 RS03600
gene id: 1778540:CVE23_RS03600
uniprot id: A0A2K8QI79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1778540:CVE23 RS01845
gene id: 1778540:CVE23_RS01845
uniprot id: A0A2K8QH34
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1778540:CVE23 RS17770
gene id: 1778540:CVE23_RS17770
uniprot id: A0A2K8QQ85
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1778540:CVE23 RS02070
gene id: 1778540:CVE23_RS02070
uniprot id: A0A2K8QIK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1778540:CVE23 RS20290
gene id: 1778540:CVE23_RS20290
uniprot id: A0A2K8QRI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1778540:CVE23 RS03665
gene id: 1778540:CVE23_RS03665
uniprot id: A0A2K8QI54
names: Similarity
messages: Belongs to the UPF0213 family.

1778540:CVE23 RS00800
gene id: 1778540:CVE23_RS00800
uniprot id: A0A2K8QGK7
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

1778540:CVE23 RS05795
gene id: 1778540:CVE23_RS05795
uniprot id: A0A2K8QJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1778540:CVE23 RS05295
gene id: 1778540:CVE23_RS05295
uniprot id: A0A2K8QK89
names: Similarity
messages: Belongs to the SufE family.

1778540:CVE23 RS16455
gene id: 1778540:CVE23_RS16455
uniprot id: A0A2K8QPK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1778540:CVE23 RS21715
gene id: 1778540:CVE23_RS21715
uniprot id: A0A2K8QTD8
names: Function
names: Subunit
messages: Homodimer.
messages: Required for resistance to the phenazine antibiotic.

1778540:CVE23 RS01580
gene id: 1778540:CVE23_RS01580
uniprot id: A0A2K8QGZ0
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1778540:CVE23 RS11525
gene id: 1778540:CVE23_RS11525
uniprot id: A0A2K8QM24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1778540:CVE23 RS11215
gene id: 1778540:CVE23_RS11215
uniprot id: A0A2K8QN61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS09045
gene id: 1778540:CVE23_RS09045
uniprot id: A0A2K8QM06
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1778540:CVE23 RS05905
gene id: 1778540:CVE23_RS05905
uniprot id: A0A2K8QJA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1778540:CVE23 RS05410
gene id: 1778540:CVE23_RS05410
uniprot id: A0A2K8QL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1778540:CVE23 RS20030
gene id: 1778540:CVE23_RS20030
uniprot id: A0A2K8QRC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1778540:CVE23 RS06855
gene id: 1778540:CVE23_RS06855
uniprot id: A0A2K8QJR5
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

1778540:CVE23 RS17470
gene id: 1778540:CVE23_RS17470
uniprot id: A0A2K8QQE4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1778540:CVE23 RS18870
gene id: 1778540:CVE23_RS18870
uniprot id: A0A2K8QSW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS13715
gene id: 1778540:CVE23_RS13715
uniprot id: A0A2K8QN55
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-90 and Arg-93) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

1778540:CVE23 RS16375
gene id: 1778540:CVE23_RS16375
uniprot id: A0A2K8QQS7
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1778540:CVE23 RS10010
gene id: 1778540:CVE23_RS10010
uniprot id: A0A2K8QL86
names: Function
names: Similarity
messages: Belongs to the TorD/DmsD family. DmsD subfamily.
messages: Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.

1778540:CVE23 RS06550
gene id: 1778540:CVE23_RS06550
uniprot id: A0A2K8QJI8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1778540:CVE23 RS21545
gene id: 1778540:CVE23_RS21545
uniprot id: A0A2K8QTA9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS19230
gene id: 1778540:CVE23_RS19230
uniprot id: A0A2K8QR02
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS03450
gene id: 1778540:CVE23_RS03450
uniprot id: A0A2K8QHZ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1778540:CVE23 RS19910
gene id: 1778540:CVE23_RS19910
uniprot id: A0A2K8QSE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

1778540:CVE23 RS17085
gene id: 1778540:CVE23_RS17085
uniprot id: A0A2K8QR27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1778540:CVE23 RS09835
gene id: 1778540:CVE23_RS09835
uniprot id: A0A2K8QL52
names: Subunit
messages: Monomer.

1778540:CVE23 RS02660
gene id: 1778540:CVE23_RS02660
uniprot id: A0A2K8QHI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1778540:CVE23 RS14185
gene id: 1778540:CVE23_RS14185
uniprot id: A0A2K8QNC7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1778540:CVE23 RS17745
gene id: 1778540:CVE23_RS17745
uniprot id: A0A2K8QQA6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS15110
gene id: 1778540:CVE23_RS15110
uniprot id: A0A2K8QR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1778540:CVE23 RS20555
gene id: 1778540:CVE23_RS20555
uniprot id: A0A2K8QRV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1778540:CVE23 RS05450
gene id: 1778540:CVE23_RS05450
uniprot id: A0A2K8QKB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1778540:CVE23 RS14850
gene id: 1778540:CVE23_RS14850
uniprot id: A0A2K8QNT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1778540:CVE23 RS06465
gene id: 1778540:CVE23_RS06465
uniprot id: A0A2K8QJG9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1778540:CVE23 RS00165
gene id: 1778540:CVE23_RS00165
uniprot id: A0A2K8QHM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS14220
gene id: 1778540:CVE23_RS14220
uniprot id: A0A2K8QNG7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1778540:CVE23 RS17395
gene id: 1778540:CVE23_RS17395
uniprot id: A0A2K8QPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS12890
gene id: 1778540:CVE23_RS12890
uniprot id: A0A2K8QMS2
names: Subcellular Location Annotation
messages: Cell inner membrane

1778540:CVE23 RS00430
gene id: 1778540:CVE23_RS00430
uniprot id: A0A2K8QGE3
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1778540:CVE23 RS20185
gene id: 1778540:CVE23_RS20185
uniprot id: A0A2K8QRN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1778540:CVE23 RS17865
gene id: 1778540:CVE23_RS17865
uniprot id: A0A2K8QQ62
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS18730
gene id: 1778540:CVE23_RS18730
uniprot id: A0A2K8QRU0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1778540:CVE23 RS13205
gene id: 1778540:CVE23_RS13205
uniprot id: A0A2K8QQ40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

1778540:CVE23 RS21280
gene id: 1778540:CVE23_RS21280
uniprot id: A0A2K8QUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1778540:CVE23 RS12040
gene id: 1778540:CVE23_RS12040
uniprot id: A0A2K8QMA9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS21410
gene id: 1778540:CVE23_RS21410
uniprot id: A0A2K8QU76
names: Subcellular Location Annotation
messages: Cell inner membrane

1778540:CVE23 RS11860
gene id: 1778540:CVE23_RS11860
uniprot id: A0A2K8QM61
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1778540:CVE23 RS07110
gene id: 1778540:CVE23_RS07110
uniprot id: A0A2K8QJS3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS11760
gene id: 1778540:CVE23_RS11760
uniprot id: A0A2K8QM36
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

1778540:CVE23 RS06205
gene id: 1778540:CVE23_RS06205
uniprot id: A0A2K8QKQ3
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS21200
gene id: 1778540:CVE23_RS21200
uniprot id: A0A2K8QRZ0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1778540:CVE23 RS02655
gene id: 1778540:CVE23_RS02655
uniprot id: A0A2K8QHQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1778540:CVE23 RS14755
gene id: 1778540:CVE23_RS14755
uniprot id: A0A2K8QNR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1778540:CVE23 RS19695
gene id: 1778540:CVE23_RS19695
uniprot id: A0A2K8QTA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

1778540:CVE23 RS16190
gene id: 1778540:CVE23_RS16190
uniprot id: A0A2K8QQR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1778540:CVE23 RS09965
gene id: 1778540:CVE23_RS09965
uniprot id: A0A2K8QLJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1778540:CVE23 RS11880
gene id: 1778540:CVE23_RS11880
uniprot id: A0A2K8QM81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

1778540:CVE23 RS14555
gene id: 1778540:CVE23_RS14555
uniprot id: A0A2K8QNL5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1778540:CVE23 RS16350
gene id: 1778540:CVE23_RS16350
uniprot id: A0A2K8QPG2
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

1778540:CVE23 RS01475
gene id: 1778540:CVE23_RS01475
uniprot id: A0A2K8QSR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1778540:CVE23 RS06645
gene id: 1778540:CVE23_RS06645
uniprot id: A0A2K8QLS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1778540:CVE23 RS14100
gene id: 1778540:CVE23_RS14100
uniprot id: A0A2K8QQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1778540:CVE23 RS01180
gene id: 1778540:CVE23_RS01180
uniprot id: A0A2K8QGT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1778540:CVE23 RS20320
gene id: 1778540:CVE23_RS20320
uniprot id: A0A2K8QRI8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS16900
gene id: 1778540:CVE23_RS16900
uniprot id: A0A2K8QQZ4
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

1778540:CVE23 RS02230
gene id: 1778540:CVE23_RS02230
uniprot id: A0A2K8QHA3
names: Similarity
messages: Belongs to the UPF0386 family.

1778540:CVE23 RS22375
gene id: 1778540:CVE23_RS22375
uniprot id: A0A2K8QSR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

1778540:CVE23 RS03565
gene id: 1778540:CVE23_RS03565
uniprot id: A0A2K8QI03
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS12900
gene id: 1778540:CVE23_RS12900
uniprot id: A0A2K8QP43
names: Similarity
messages: Belongs to the peptidase S1B family.

1778540:CVE23 RS13185
gene id: 1778540:CVE23_RS13185
uniprot id: A0A2K8QMX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1778540:CVE23 RS13550
gene id: 1778540:CVE23_RS13550
uniprot id: A0A2K8QN34
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1778540:CVE23 RS01080
gene id: 1778540:CVE23_RS01080
uniprot id: A0A2K8QGQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1778540:CVE23 RS15545
gene id: 1778540:CVE23_RS15545
uniprot id: A0A2K8QQA3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS10180
gene id: 1778540:CVE23_RS10180
uniprot id: A0A2K8QLB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

1778540:CVE23 RS16655
gene id: 1778540:CVE23_RS16655
uniprot id: A0A2K8QPL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1778540:CVE23 RS20505
gene id: 1778540:CVE23_RS20505
uniprot id: A0A2K8QRN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1778540:CVE23 RS14815
gene id: 1778540:CVE23_RS14815
uniprot id: A0A2K8QNN6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1778540:CVE23 RS07130
gene id: 1778540:CVE23_RS07130
uniprot id: A0A2K8QJW0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1778540:CVE23 RS22365
gene id: 1778540:CVE23_RS22365
uniprot id: A0A2K8QSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS06720
gene id: 1778540:CVE23_RS06720
uniprot id: A0A2K8QJK6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS02285
gene id: 1778540:CVE23_RS02285
uniprot id: A0A2K8QHB3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS14895
gene id: 1778540:CVE23_RS14895
uniprot id: A0A2K8QNS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS17035
gene id: 1778540:CVE23_RS17035
uniprot id: A0A2K8QPT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1778540:CVE23 RS11845
gene id: 1778540:CVE23_RS11845
uniprot id: A0A2K8QM93
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1778540:CVE23 RS20530
gene id: 1778540:CVE23_RS20530
uniprot id: A0A2K8QSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1778540:CVE23 RS16990
gene id: 1778540:CVE23_RS16990
uniprot id: A0A2K8QS11
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1778540:CVE23 RS10915
gene id: 1778540:CVE23_RS10915
uniprot id: A0A2K8QN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS11790
gene id: 1778540:CVE23_RS11790
uniprot id: A0A2K8QNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.
messages: Membrane

1778540:CVE23 RS14210
gene id: 1778540:CVE23_RS14210
uniprot id: A0A2K8QNR3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1778540:CVE23 RS20510
gene id: 1778540:CVE23_RS20510
uniprot id: A0A2K8QSS9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1778540:CVE23 RS03650
gene id: 1778540:CVE23_RS03650
uniprot id: A0A2K8QI56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1778540:CVE23 RS00775
gene id: 1778540:CVE23_RS00775
uniprot id: A0A2K8QGS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1778540:CVE23 RS06565
gene id: 1778540:CVE23_RS06565
uniprot id: A0A2K8QJK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1778540:CVE23 RS21975
gene id: 1778540:CVE23_RS21975
uniprot id: A0A2K8QTF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1778540:CVE23 RS16775
gene id: 1778540:CVE23_RS16775
uniprot id: A0A2K8QPP2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1778540:CVE23 RS11210
gene id: 1778540:CVE23_RS11210
uniprot id: A0A2K8QLY7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1778540:CVE23 RS14315
gene id: 1778540:CVE23_RS14315
uniprot id: A0A2K8QNH5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

1778540:CVE23 RS03825
gene id: 1778540:CVE23_RS03825
uniprot id: A0A2K8QKC7
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS22320
gene id: 1778540:CVE23_RS22320
uniprot id: A0A2K8QSQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1778540:CVE23 RS06615
gene id: 1778540:CVE23_RS06615
uniprot id: A0A2K8QJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS07220
gene id: 1778540:CVE23_RS07220
uniprot id: A0A2K8QUZ2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1778540:CVE23 RS21245
gene id: 1778540:CVE23_RS21245
uniprot id: A0A2K8QS02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

1778540:CVE23 RS15445
gene id: 1778540:CVE23_RS15445
uniprot id: A0A2K8QP38
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS20160
gene id: 1778540:CVE23_RS20160
uniprot id: A0A2K8QRE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1778540:CVE23 RS20270
gene id: 1778540:CVE23_RS20270
uniprot id: A0A2K8QRH7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1778540:CVE23 RS08495
gene id: 1778540:CVE23_RS08495
uniprot id: A0A2K8QKH0
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1778540:CVE23 RS22355
gene id: 1778540:CVE23_RS22355
uniprot id: A0A2K8QSU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1778540:CVE23 RS16810
gene id: 1778540:CVE23_RS16810
uniprot id: A0A2K8QPR2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1778540:CVE23 RS17220
gene id: 1778540:CVE23_RS17220
uniprot id: A0A2K8QPV4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1778540:CVE23 RS12990
gene id: 1778540:CVE23_RS12990
uniprot id: A0A2K8QMU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1778540:CVE23 RS00735
gene id: 1778540:CVE23_RS00735
uniprot id: A0A2K8QHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS09870
gene id: 1778540:CVE23_RS09870
uniprot id: A0A2K8QL74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS15175
gene id: 1778540:CVE23_RS15175
uniprot id: A0A2K8QR72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1778540:CVE23 RS14775
gene id: 1778540:CVE23_RS14775
uniprot id: A0A2K8QQZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS10330
gene id: 1778540:CVE23_RS10330
uniprot id: A0A2K8QLD7
names: Similarity
messages: Belongs to the RNase T2 family.

1778540:CVE23 RS16300
gene id: 1778540:CVE23_RS16300
uniprot id: A0A2K8QQR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS20585
gene id: 1778540:CVE23_RS20585
uniprot id: A0A2K8QSR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

1778540:CVE23 RS10880
gene id: 1778540:CVE23_RS10880
uniprot id: A0A2K8QLP9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS19300
gene id: 1778540:CVE23_RS19300
uniprot id: A0A2K8QTK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

1778540:CVE23 RS20300
gene id: 1778540:CVE23_RS20300
uniprot id: A0A2K8QSN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

1778540:CVE23 RS05210
gene id: 1778540:CVE23_RS05210
uniprot id: A0A2K8QIU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1778540:CVE23 RS10070
gene id: 1778540:CVE23_RS10070
uniprot id: A0A2K8QU58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1778540:CVE23 RS06005
gene id: 1778540:CVE23_RS06005
uniprot id: A0A2K8QLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1778540:CVE23 RS15340
gene id: 1778540:CVE23_RS15340
uniprot id: A0A2K8QTC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS05000
gene id: 1778540:CVE23_RS05000
uniprot id: A0A2K8QIU7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1778540:CVE23 RS15085
gene id: 1778540:CVE23_RS15085
uniprot id: A0A2K8QNX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1778540:CVE23 RS20175
gene id: 1778540:CVE23_RS20175
uniprot id: A0A2K8QTI6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1778540:CVE23 RS01480
gene id: 1778540:CVE23_RS01480
uniprot id: A0A2K8QI98
names: Similarity
messages: Belongs to the MreC family.

1778540:CVE23 RS20265
gene id: 1778540:CVE23_RS20265
uniprot id: A0A2K8QSK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1778540:CVE23 RS19250
gene id: 1778540:CVE23_RS19250
uniprot id: A0A2K8QS36
names: Similarity
messages: Belongs to the UPF0246 family.

1778540:CVE23 RS06215
gene id: 1778540:CVE23_RS06215
uniprot id: A0A2K8QLJ0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1778540:CVE23 RS20695
gene id: 1778540:CVE23_RS20695
uniprot id: A0A2K8QRR0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1778540:CVE23 RS10280
gene id: 1778540:CVE23_RS10280
uniprot id: A0A2K8QMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

1778540:CVE23 RS16405
gene id: 1778540:CVE23_RS16405
uniprot id: A0A2K8QPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1778540:CVE23 RS06015
gene id: 1778540:CVE23_RS06015
uniprot id: A0A2K8QJI1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1778540:CVE23 RS03305
gene id: 1778540:CVE23_RS03305
uniprot id: A0A2K8QJ74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS17645
gene id: 1778540:CVE23_RS17645
uniprot id: A0A2K8QQ25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1778540:CVE23 RS07620
gene id: 1778540:CVE23_RS07620
uniprot id: A0A2K8QM86
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1778540:CVE23 RS15115
gene id: 1778540:CVE23_RS15115
uniprot id: A0A2K8QNW8
names: Similarity
messages: Belongs to the isochorismate synthase family.

1778540:CVE23 RS19520
gene id: 1778540:CVE23_RS19520
uniprot id: A0A2K8QR28
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS17075
gene id: 1778540:CVE23_RS17075
uniprot id: A0A2K8QPT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1778540:CVE23 RS02870
gene id: 1778540:CVE23_RS02870
uniprot id: A0A2K8QJV0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS20525
gene id: 1778540:CVE23_RS20525
uniprot id: A0A2K8QTE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1778540:CVE23 RS09760
gene id: 1778540:CVE23_RS09760
uniprot id: A0A2K8QL34
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1778540:CVE23 RS20735
gene id: 1778540:CVE23_RS20735
uniprot id: A0A2K8QSX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS06860
gene id: 1778540:CVE23_RS06860
uniprot id: A0A2K8QKY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

1778540:CVE23 RS02675
gene id: 1778540:CVE23_RS02675
uniprot id: A0A2K8QHK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1778540:CVE23 RS09885
gene id: 1778540:CVE23_RS09885
uniprot id: A0A2K8QL54
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS21355
gene id: 1778540:CVE23_RS21355
uniprot id: A0A2K8QU63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

1778540:CVE23 RS10220
gene id: 1778540:CVE23_RS10220
uniprot id: A0A2K8QT53
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1778540:CVE23 RS05435
gene id: 1778540:CVE23_RS05435
uniprot id: A0A2K8QK75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1778540:CVE23 RS18655
gene id: 1778540:CVE23_RS18655
uniprot id: A0A2K8QQY9
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1778540:CVE23 RS07750
gene id: 1778540:CVE23_RS07750
uniprot id: A0A2K8QLD1
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS13485
gene id: 1778540:CVE23_RS13485
uniprot id: A0A2K8QMZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

1778540:CVE23 RS14960
gene id: 1778540:CVE23_RS14960
uniprot id: A0A2K8QNV2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS21290
gene id: 1778540:CVE23_RS21290
uniprot id: A0A2K8QT61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

1778540:CVE23 RS06790
gene id: 1778540:CVE23_RS06790
uniprot id: A0A2K8QJQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1778540:CVE23 RS14275
gene id: 1778540:CVE23_RS14275
uniprot id: A0A2K8QNH7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1778540:CVE23 RS03680
gene id: 1778540:CVE23_RS03680
uniprot id: A0A2K8QI34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1778540:CVE23 RS09845
gene id: 1778540:CVE23_RS09845
uniprot id: A0A2K8QL56
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1778540:CVE23 RS06745
gene id: 1778540:CVE23_RS06745
uniprot id: A0A2K8QJW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1778540:CVE23 RS13275
gene id: 1778540:CVE23_RS13275
uniprot id: A0A2K8QMY1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

1778540:CVE23 RS06090
gene id: 1778540:CVE23_RS06090
uniprot id: A0A2K8QJA6
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1778540:CVE23 RS19530
gene id: 1778540:CVE23_RS19530
uniprot id: A0A2K8QT65
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1778540:CVE23 RS00050
gene id: 1778540:CVE23_RS00050
uniprot id: A0A2K8QHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1778540:CVE23 RS21535
gene id: 1778540:CVE23_RS21535
uniprot id: A0A2K8QS45
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1778540:CVE23 RS11050
gene id: 1778540:CVE23_RS11050
uniprot id: A0A2K8QLV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1778540:CVE23 RS04730
gene id: 1778540:CVE23_RS04730
uniprot id: A0A2K8QKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1778540:CVE23 RS11515
gene id: 1778540:CVE23_RS11515
uniprot id: A0A2K8QLZ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1778540:CVE23 RS12635
gene id: 1778540:CVE23_RS12635
uniprot id: A0A2K8QMJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

1778540:CVE23 RS04805
gene id: 1778540:CVE23_RS04805
uniprot id: A0A2K8QIQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1778540:CVE23 RS00505
gene id: 1778540:CVE23_RS00505
uniprot id: A0A2K8QGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1778540:CVE23 RS09430
gene id: 1778540:CVE23_RS09430
uniprot id: A0A2K8QKX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS08815
gene id: 1778540:CVE23_RS08815
uniprot id: A0A2K8QKN1
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS06175
gene id: 1778540:CVE23_RS06175
uniprot id: A0A2K8QJB8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1778540:CVE23 RS10110
gene id: 1778540:CVE23_RS10110
uniprot id: A0A2K8QLA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1778540:CVE23 RS11045
gene id: 1778540:CVE23_RS11045
uniprot id: A0A2K8QLT7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1778540:CVE23 RS04785
gene id: 1778540:CVE23_RS04785
uniprot id: A0A2K8QKW2
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS01615
gene id: 1778540:CVE23_RS01615
uniprot id: A0A2K8QGY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1778540:CVE23 RS20400
gene id: 1778540:CVE23_RS20400
uniprot id: A0A2K8QRK6
names: Similarity
messages: Belongs to the UPF0270 family.

1778540:CVE23 RS18885
gene id: 1778540:CVE23_RS18885
uniprot id: A0A2K8QQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1778540:CVE23 RS00740
gene id: 1778540:CVE23_RS00740
uniprot id: A0A2K8QGK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS20140
gene id: 1778540:CVE23_RS20140
uniprot id: A0A2K8QRE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1778540:CVE23 RS22525
gene id: 1778540:CVE23_RS22525
uniprot id: A0A2K8QSR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1778540:CVE23 RS10895
gene id: 1778540:CVE23_RS10895
uniprot id: A0A2K8QLS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1778540:CVE23 RS03605
gene id: 1778540:CVE23_RS03605
uniprot id: A0A2K8QI11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1778540:CVE23 RS14245
gene id: 1778540:CVE23_RS14245
uniprot id: A0A2K8QNE1
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1778540:CVE23 RS14855
gene id: 1778540:CVE23_RS14855
uniprot id: A0A2K8QPY5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS20655
gene id: 1778540:CVE23_RS20655
uniprot id: A0A2K8QRQ3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1778540:CVE23 RS05505
gene id: 1778540:CVE23_RS05505
uniprot id: A0A2K8QKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1778540:CVE23 RS21045
gene id: 1778540:CVE23_RS21045
uniprot id: A0A2K8QS47
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1778540:CVE23 RS22360
gene id: 1778540:CVE23_RS22360
uniprot id: A0A2K8QSL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1778540:CVE23 RS14280
gene id: 1778540:CVE23_RS14280
uniprot id: A0A2K8QPM6
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1778540:CVE23 RS09140
gene id: 1778540:CVE23_RS09140
uniprot id: A0A2K8QKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS13860
gene id: 1778540:CVE23_RS13860
uniprot id: A0A2K8QQG1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1778540:CVE23 RS21035
gene id: 1778540:CVE23_RS21035
uniprot id: A0A2K8QRX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1778540:CVE23 RS20725
gene id: 1778540:CVE23_RS20725
uniprot id: A0A2K8QRR6
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS12610
gene id: 1778540:CVE23_RS12610
uniprot id: A0A2K8QMN0
names: Similarity
messages: Belongs to the peptidase S41A family.

1778540:CVE23 RS00010
gene id: 1778540:CVE23_RS00010
uniprot id: A0A2K8QG52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1778540:CVE23 RS07310
gene id: 1778540:CVE23_RS07310
uniprot id: A0A2K8QT59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1778540:CVE23 RS08075
gene id: 1778540:CVE23_RS08075
uniprot id: A0A2K8QKA2
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS04230
gene id: 1778540:CVE23_RS04230
uniprot id: A0A2K8QJK2
names: Similarity
messages: Belongs to the TPP enzyme family.

1778540:CVE23 RS14820
gene id: 1778540:CVE23_RS14820
uniprot id: A0A2K8QQ39
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1778540:CVE23 RS17600
gene id: 1778540:CVE23_RS17600
uniprot id: A0A2K8QR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS04625
gene id: 1778540:CVE23_RS04625
uniprot id: A0A2K8QIJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1778540:CVE23 RS19435
gene id: 1778540:CVE23_RS19435
uniprot id: A0A2K8QR29
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1778540:CVE23 RS01590
gene id: 1778540:CVE23_RS01590
uniprot id: A0A2K8QIB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1778540:CVE23 RS09955
gene id: 1778540:CVE23_RS09955
uniprot id: A0A2K8QNF7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1778540:CVE23 RS17665
gene id: 1778540:CVE23_RS17665
uniprot id: A0A2K8QQ66
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1778540:CVE23 RS14995
gene id: 1778540:CVE23_RS14995
uniprot id: A0A2K8QNU7
names: Similarity
messages: Belongs to the UPF0115 family.

1778540:CVE23 RS03850
gene id: 1778540:CVE23_RS03850
uniprot id: A0A2K8QJC5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS08845
gene id: 1778540:CVE23_RS08845
uniprot id: A0A2K8QKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS15075
gene id: 1778540:CVE23_RS15075
uniprot id: A0A2K8QNX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
messages: Cell inner membrane
messages: Component of an export pathway for enterobactin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1778540:CVE23 RS10545
gene id: 1778540:CVE23_RS10545
uniprot id: A0A2K8QLH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS05810
gene id: 1778540:CVE23_RS05810
uniprot id: A0A2K8QSX2
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS00785
gene id: 1778540:CVE23_RS00785
uniprot id: A0A2K8QGP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1778540:CVE23 RS17885
gene id: 1778540:CVE23_RS17885
uniprot id: A0A2K8QQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1778540:CVE23 RS20470
gene id: 1778540:CVE23_RS20470
uniprot id: A0A2K8QRL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1778540:CVE23 RS16710
gene id: 1778540:CVE23_RS16710
uniprot id: A0A2K8QPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1778540:CVE23 RS10045
gene id: 1778540:CVE23_RS10045
uniprot id: A0A2K8QL84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1778540:CVE23 RS16970
gene id: 1778540:CVE23_RS16970
uniprot id: A0A2K8QPR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

1778540:CVE23 RS16955
gene id: 1778540:CVE23_RS16955
uniprot id: A0A2K8QPS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1778540:CVE23 RS00390
gene id: 1778540:CVE23_RS00390
uniprot id: A0A2K8QGD9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1778540:CVE23 RS11825
gene id: 1778540:CVE23_RS11825
uniprot id: A0A2K8QPD8
names: Similarity
messages: Belongs to the RutC family.

1778540:CVE23 RS15985
gene id: 1778540:CVE23_RS15985
uniprot id: A0A2K8QP99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

1778540:CVE23 RS11410
gene id: 1778540:CVE23_RS11410
uniprot id: A0A2K8QMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS06515
gene id: 1778540:CVE23_RS06515
uniprot id: A0A2K8QJH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1778540:CVE23 RS13075
gene id: 1778540:CVE23_RS13075
uniprot id: A0A2K8QP70
names: Similarity
messages: Belongs to the PspA/IM30 family.

1778540:CVE23 RS13255
gene id: 1778540:CVE23_RS13255
uniprot id: A0A2K8QP98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

1778540:CVE23 RS00990
gene id: 1778540:CVE23_RS00990
uniprot id: A0A2K8QIW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1778540:CVE23 RS04655
gene id: 1778540:CVE23_RS04655
uniprot id: A0A2K8QJT7
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS08070
gene id: 1778540:CVE23_RS08070
uniprot id: A0A2K8QLI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS10085
gene id: 1778540:CVE23_RS10085
uniprot id: A0A2K8QLC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1778540:CVE23 RS09555
gene id: 1778540:CVE23_RS09555
uniprot id: A0A2K8QME5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1778540:CVE23 RS14000
gene id: 1778540:CVE23_RS14000
uniprot id: A0A2K8QN98
names: Similarity
messages: Belongs to the peptidase S16 family.

1778540:CVE23 RS14750
gene id: 1778540:CVE23_RS14750
uniprot id: A0A2K8QPW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1778540:CVE23 RS07050
gene id: 1778540:CVE23_RS07050
uniprot id: A0A2K8QSV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

1778540:CVE23 RS01900
gene id: 1778540:CVE23_RS01900
uniprot id: A0A2K8QH44
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS05385
gene id: 1778540:CVE23_RS05385
uniprot id: A0A2K8QIY2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS06850
gene id: 1778540:CVE23_RS06850
uniprot id: A0A2K8QJN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1778540:CVE23 RS17020
gene id: 1778540:CVE23_RS17020
uniprot id: A0A2K8QPX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1778540:CVE23 RS01605
gene id: 1778540:CVE23_RS01605
uniprot id: A0A2K8QH37
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS14835
gene id: 1778540:CVE23_RS14835
uniprot id: A0A2K8QNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS14525
gene id: 1778540:CVE23_RS14525
uniprot id: A0A2K8QNM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS05845
gene id: 1778540:CVE23_RS05845
uniprot id: A0A2K8QJ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1778540:CVE23 RS03835
gene id: 1778540:CVE23_RS03835
uniprot id: A0A2K8QIB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1778540:CVE23 RS14480
gene id: 1778540:CVE23_RS14480
uniprot id: A0A2K8QPY0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1778540:CVE23 RS07125
gene id: 1778540:CVE23_RS07125
uniprot id: A0A2K8QM05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

1778540:CVE23 RS01640
gene id: 1778540:CVE23_RS01640
uniprot id: A0A2K8QIC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1778540:CVE23 RS10930
gene id: 1778540:CVE23_RS10930
uniprot id: A0A2K8QLQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS01285
gene id: 1778540:CVE23_RS01285
uniprot id: A0A2K8QGV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS03485
gene id: 1778540:CVE23_RS03485
uniprot id: A0A2K8QI58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1778540:CVE23 RS07235
gene id: 1778540:CVE23_RS07235
uniprot id: A0A2K8QJV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1778540:CVE23 RS17910
gene id: 1778540:CVE23_RS17910
uniprot id: A0A2K8QRH3
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS18080
gene id: 1778540:CVE23_RS18080
uniprot id: A0A2K8QQA5
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1778540:CVE23 RS14155
gene id: 1778540:CVE23_RS14155
uniprot id: A0A2K8QNE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1778540:CVE23 RS12220
gene id: 1778540:CVE23_RS12220
uniprot id: A0A2K8QMG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

1778540:CVE23 RS20180
gene id: 1778540:CVE23_RS20180
uniprot id: A0A2K8QRG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1778540:CVE23 RS05335
gene id: 1778540:CVE23_RS05335
uniprot id: A0A2K8QIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

1778540:CVE23 RS14370
gene id: 1778540:CVE23_RS14370
uniprot id: A0A2K8QNI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1778540:CVE23 RS12005
gene id: 1778540:CVE23_RS12005
uniprot id: A0A2K8QMC3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1778540:CVE23 RS14120
gene id: 1778540:CVE23_RS14120
uniprot id: A0A2K8QNE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1778540:CVE23 RS09335
gene id: 1778540:CVE23_RS09335
uniprot id: A0A2K8QMA5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS06060
gene id: 1778540:CVE23_RS06060
uniprot id: A0A2K8QJC7
names: Similarity
messages: Belongs to the P(II) protein family.

1778540:CVE23 RS22265
gene id: 1778540:CVE23_RS22265
uniprot id: A0A2K8QUJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1778540:CVE23 RS12400
gene id: 1778540:CVE23_RS12400
uniprot id: A0A2K8QT42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS10975
gene id: 1778540:CVE23_RS10975
uniprot id: A0A2K8QP02
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1778540:CVE23 RS02085
gene id: 1778540:CVE23_RS02085
uniprot id: A0A2K8QHC4
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS06545
gene id: 1778540:CVE23_RS06545
uniprot id: A0A2K8QJT3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1778540:CVE23 RS03330
gene id: 1778540:CVE23_RS03330
uniprot id: A0A2K8QHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS22445
gene id: 1778540:CVE23_RS22445
uniprot id: A0A2K8QUQ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS19000
gene id: 1778540:CVE23_RS19000
uniprot id: A0A2K8QQW4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1778540:CVE23 RS08020
gene id: 1778540:CVE23_RS08020
uniprot id: A0A2K8QK92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS14355
gene id: 1778540:CVE23_RS14355
uniprot id: A0A2K8QPW4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1778540:CVE23 RS16695
gene id: 1778540:CVE23_RS16695
uniprot id: A0A2K8QPM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1778540:CVE23 RS13580
gene id: 1778540:CVE23_RS13580
uniprot id: A0A2K8QN15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1778540:CVE23 RS09345
gene id: 1778540:CVE23_RS09345
uniprot id: A0A2K8QN46
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1778540:CVE23 RS21250
gene id: 1778540:CVE23_RS21250
uniprot id: A0A2K8QS84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1778540:CVE23 RS16735
gene id: 1778540:CVE23_RS16735
uniprot id: A0A2K8QRX0
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS11530
gene id: 1778540:CVE23_RS11530
uniprot id: A0A2K8QMD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

1778540:CVE23 RS18600
gene id: 1778540:CVE23_RS18600
uniprot id: A0A2K8QQK6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1778540:CVE23 RS19785
gene id: 1778540:CVE23_RS19785
uniprot id: A0A2K8QR76
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1778540:CVE23 RS15035
gene id: 1778540:CVE23_RS15035
uniprot id: A0A2K8QQ78
names: Similarity
messages: Belongs to the MQO family.

1778540:CVE23 RS15575
gene id: 1778540:CVE23_RS15575
uniprot id: A0A2K8QP45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS19945
gene id: 1778540:CVE23_RS19945
uniprot id: A0A2K8QSH7
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1778540:CVE23 RS12865
gene id: 1778540:CVE23_RS12865
uniprot id: A0A2K8QN22
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1778540:CVE23 RS22075
gene id: 1778540:CVE23_RS22075
uniprot id: A0A2K8QSI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1778540:CVE23 RS01430
gene id: 1778540:CVE23_RS01430
uniprot id: A0A2K8QGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1778540:CVE23 RS04865
gene id: 1778540:CVE23_RS04865
uniprot id: A0A2K8QIP2
names: Subcellular Location Annotation
messages: Cell inner membrane

1778540:CVE23 RS06390
gene id: 1778540:CVE23_RS06390
uniprot id: A0A2K8QJF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1778540:CVE23 RS05140
gene id: 1778540:CVE23_RS05140
uniprot id: A0A2K8QK26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

1778540:CVE23 RS08940
gene id: 1778540:CVE23_RS08940
uniprot id: A0A2K8QKQ4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

1778540:CVE23 RS01975
gene id: 1778540:CVE23_RS01975
uniprot id: A0A2K8QHA4
names: Similarity
messages: Belongs to the UPF0306 family.

1778540:CVE23 RS13935
gene id: 1778540:CVE23_RS13935
uniprot id: A0A2K8QNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

1778540:CVE23 RS07060
gene id: 1778540:CVE23_RS07060
uniprot id: A0A2K8QL57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1778540:CVE23 RS04425
gene id: 1778540:CVE23_RS04425
uniprot id: A0A2K8QII0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS15585
gene id: 1778540:CVE23_RS15585
uniprot id: A0A2K8QP26
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1778540:CVE23 RS17290
gene id: 1778540:CVE23_RS17290
uniprot id: A0A2K8QQ09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS06585
gene id: 1778540:CVE23_RS06585
uniprot id: A0A2K8QLR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1778540:CVE23 RS12075
gene id: 1778540:CVE23_RS12075
uniprot id: A0A2K8QNP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1778540:CVE23 RS21090
gene id: 1778540:CVE23_RS21090
uniprot id: A0A2K8QT23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS10935
gene id: 1778540:CVE23_RS10935
uniprot id: A0A2K8QM31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS01740
gene id: 1778540:CVE23_RS01740
uniprot id: A0A2K8QH15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

1778540:CVE23 RS13300
gene id: 1778540:CVE23_RS13300
uniprot id: A0A2K8QMZ7
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

1778540:CVE23 RS11865
gene id: 1778540:CVE23_RS11865
uniprot id: A0A2K8QNK8
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS08920
gene id: 1778540:CVE23_RS08920
uniprot id: A0A2K8QKZ4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1778540:CVE23 RS13195
gene id: 1778540:CVE23_RS13195
uniprot id: A0A2K8QP88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS17785
gene id: 1778540:CVE23_RS17785
uniprot id: A0A2K8QQ67
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1778540:CVE23 RS21135
gene id: 1778540:CVE23_RS21135
uniprot id: A0A2K8QRZ5
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS19155
gene id: 1778540:CVE23_RS19155
uniprot id: A0A2K8QQX8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1778540:CVE23 RS06100
gene id: 1778540:CVE23_RS06100
uniprot id: A0A2K8QKN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1778540:CVE23 RS03965
gene id: 1778540:CVE23_RS03965
uniprot id: A0A2K8QI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS12390
gene id: 1778540:CVE23_RS12390
uniprot id: A0A2K8QMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1778540:CVE23 RS07785
gene id: 1778540:CVE23_RS07785
uniprot id: A0A2K8QMB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS10625
gene id: 1778540:CVE23_RS10625
uniprot id: A0A2K8QLL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS10845
gene id: 1778540:CVE23_RS10845
uniprot id: A0A2K8QMZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1778540:CVE23 RS14170
gene id: 1778540:CVE23_RS14170
uniprot id: A0A2K8QNF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1778540:CVE23 RS17855
gene id: 1778540:CVE23_RS17855
uniprot id: A0A2K8QUE7
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS10055
gene id: 1778540:CVE23_RS10055
uniprot id: A0A2K8QL90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1778540:CVE23 RS19190
gene id: 1778540:CVE23_RS19190
uniprot id: A0A2K8QQW6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1778540:CVE23 RS05190
gene id: 1778540:CVE23_RS05190
uniprot id: A0A2K8QIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

1778540:CVE23 RS07175
gene id: 1778540:CVE23_RS07175
uniprot id: A0A2K8QJU5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1778540:CVE23 RS18835
gene id: 1778540:CVE23_RS18835
uniprot id: A0A2K8QQQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1778540:CVE23 RS22385
gene id: 1778540:CVE23_RS22385
uniprot id: A0A2K8QTQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS10285
gene id: 1778540:CVE23_RS10285
uniprot id: A0A2K8QLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

1778540:CVE23 RS21790
gene id: 1778540:CVE23_RS21790
uniprot id: A0A2K8QSA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

1778540:CVE23 RS03480
gene id: 1778540:CVE23_RS03480
uniprot id: A0A2K8QI27
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1778540:CVE23 RS20150
gene id: 1778540:CVE23_RS20150
uniprot id: A0A2K8QSK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1778540:CVE23 RS17715
gene id: 1778540:CVE23_RS17715
uniprot id: A0A2K8QQ74
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1778540:CVE23 RS02140
gene id: 1778540:CVE23_RS02140
uniprot id: A0A2K8QHH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1778540:CVE23 RS12295
gene id: 1778540:CVE23_RS12295
uniprot id: A0A2K8QME0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS20295
gene id: 1778540:CVE23_RS20295
uniprot id: A0A2K8QRI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1778540:CVE23 RS17755
gene id: 1778540:CVE23_RS17755
uniprot id: A0A2K8QRD1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1778540:CVE23 RS06890
gene id: 1778540:CVE23_RS06890
uniprot id: A0A2K8QJS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS01825
gene id: 1778540:CVE23_RS01825
uniprot id: A0A2K8QHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1778540:CVE23 RS07710
gene id: 1778540:CVE23_RS07710
uniprot id: A0A2K8QK20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1778540:CVE23 RS05370
gene id: 1778540:CVE23_RS05370
uniprot id: A0A2K8QIX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1778540:CVE23 RS06470
gene id: 1778540:CVE23_RS06470
uniprot id: A0A2K8QKV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS01145
gene id: 1778540:CVE23_RS01145
uniprot id: A0A2K8QGY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1778540:CVE23 RS20205
gene id: 1778540:CVE23_RS20205
uniprot id: A0A2K8QRL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1778540:CVE23 RS05980
gene id: 1778540:CVE23_RS05980
uniprot id: A0A2K8QKH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Membrane

1778540:CVE23 RS02450
gene id: 1778540:CVE23_RS02450
uniprot id: A0A2K8QHG0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaSR operon in response to L-rhamnose.
messages: Binds DNA as a dimer.
messages: Cytoplasm

1778540:CVE23 RS17485
gene id: 1778540:CVE23_RS17485
uniprot id: A0A2K8QR95
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS11115
gene id: 1778540:CVE23_RS11115
uniprot id: A0A2K8QLV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1778540:CVE23 RS00675
gene id: 1778540:CVE23_RS00675
uniprot id: A0A2K8QGI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS10050
gene id: 1778540:CVE23_RS10050
uniprot id: A0A2K8QMN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS20170
gene id: 1778540:CVE23_RS20170
uniprot id: A0A2K8QRG1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1778540:CVE23 RS06495
gene id: 1778540:CVE23_RS06495
uniprot id: A0A2K8QJI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1778540:CVE23 RS10530
gene id: 1778540:CVE23_RS10530
uniprot id: A0A2K8QLK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1778540:CVE23 RS14310
gene id: 1778540:CVE23_RS14310
uniprot id: A0A2K8QT64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

1778540:CVE23 RS19595
gene id: 1778540:CVE23_RS19595
uniprot id: A0A2K8QR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS22205
gene id: 1778540:CVE23_RS22205
uniprot id: A0A2K8QTL9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS00965
gene id: 1778540:CVE23_RS00965
uniprot id: A0A2K8QHW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1778540:CVE23 RS16285
gene id: 1778540:CVE23_RS16285
uniprot id: A0A2K8QPW7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1778540:CVE23 RS11355
gene id: 1778540:CVE23_RS11355
uniprot id: A0A2K8QLZ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10B family.
messages: Binds 1 zinc ion per subunit.

1778540:CVE23 RS21610
gene id: 1778540:CVE23_RS21610
uniprot id: A0A2K8QTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

1778540:CVE23 RS11855
gene id: 1778540:CVE23_RS11855
uniprot id: A0A2K8QM79
names: Similarity
messages: Belongs to the UPF0053 family.

1778540:CVE23 RS13545
gene id: 1778540:CVE23_RS13545
uniprot id: A0A2K8QQ99
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1778540:CVE23 RS18845
gene id: 1778540:CVE23_RS18845
uniprot id: A0A2K8QRW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1778540:CVE23 RS22535
gene id: 1778540:CVE23_RS22535
uniprot id: A0A2K8QSU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1778540:CVE23 RS05790
gene id: 1778540:CVE23_RS05790
uniprot id: A0A2K8QLB3
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1778540:CVE23 RS19725
gene id: 1778540:CVE23_RS19725
uniprot id: A0A2K8QRD0
names: Similarity
messages: Belongs to the NifX/NifY family.

1778540:CVE23 RS09475
gene id: 1778540:CVE23_RS09475
uniprot id: A0A2K8QKZ5
names: Similarity
messages: Belongs to the ArsC family.

1778540:CVE23 RS21040
gene id: 1778540:CVE23_RS21040
uniprot id: A0A2K8QTE3
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

1778540:CVE23 RS02405
gene id: 1778540:CVE23_RS02405
uniprot id: A0A2K8QHE1
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS14055
gene id: 1778540:CVE23_RS14055
uniprot id: A0A2K8QPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1778540:CVE23 RS12615
gene id: 1778540:CVE23_RS12615
uniprot id: A0A2K8QNU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

1778540:CVE23 RS05395
gene id: 1778540:CVE23_RS05395
uniprot id: A0A2K8QUX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1778540:CVE23 RS01165
gene id: 1778540:CVE23_RS01165
uniprot id: A0A2K8QGS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1778540:CVE23 RS17025
gene id: 1778540:CVE23_RS17025
uniprot id: A0A2K8QPS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1778540:CVE23 RS21145
gene id: 1778540:CVE23_RS21145
uniprot id: A0A2K8QS04
names: Similarity
messages: Belongs to the UPF0438 family.

1778540:CVE23 RS20380
gene id: 1778540:CVE23_RS20380
uniprot id: A0A2K8QTM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

1778540:CVE23 RS06165
gene id: 1778540:CVE23_RS06165
uniprot id: A0A2K8QJF1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1778540:CVE23 RS03245
gene id: 1778540:CVE23_RS03245
uniprot id: A0A2K8QHV0
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1778540:CVE23 RS17360
gene id: 1778540:CVE23_RS17360
uniprot id: A0A2K8QS57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1778540:CVE23 RS04180
gene id: 1778540:CVE23_RS04180
uniprot id: A0A2K8QJJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1778540:CVE23 RS03295
gene id: 1778540:CVE23_RS03295
uniprot id: A0A2K8QHW2
names: Similarity
messages: Belongs to the Fur family.

1778540:CVE23 RS17340
gene id: 1778540:CVE23_RS17340
uniprot id: A0A2K8QQ19
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1778540:CVE23 RS00380
gene id: 1778540:CVE23_RS00380
uniprot id: A0A2K8QGD5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1778540:CVE23 RS11890
gene id: 1778540:CVE23_RS11890
uniprot id: A0A2K8QMJ5
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS14405
gene id: 1778540:CVE23_RS14405
uniprot id: A0A2K8QPP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1778540:CVE23 RS21865
gene id: 1778540:CVE23_RS21865
uniprot id: A0A2K8QTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1778540:CVE23 RS20460
gene id: 1778540:CVE23_RS20460
uniprot id: A0A2K8QSS0
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS12980
gene id: 1778540:CVE23_RS12980
uniprot id: A0A2K8QMU8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1778540:CVE23 RS01445
gene id: 1778540:CVE23_RS01445
uniprot id: A0A2K8QH36
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1778540:CVE23 RS10885
gene id: 1778540:CVE23_RS10885
uniprot id: A0A2K8QM22
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

1778540:CVE23 RS14825
gene id: 1778540:CVE23_RS14825
uniprot id: A0A2K8QNN9
names: Similarity
messages: Belongs to the GST superfamily.

1778540:CVE23 RS18840
gene id: 1778540:CVE23_RS18840
uniprot id: A0A2K8QQU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1778540:CVE23 RS14445
gene id: 1778540:CVE23_RS14445
uniprot id: A0A2K8QNJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1778540:CVE23 RS01860
gene id: 1778540:CVE23_RS01860
uniprot id: A0A2K8QH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS07205
gene id: 1778540:CVE23_RS07205
uniprot id: A0A2K8QL42
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1778540:CVE23 RS19090
gene id: 1778540:CVE23_RS19090
uniprot id: A0A2K8QQS6
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1778540:CVE23 RS14805
gene id: 1778540:CVE23_RS14805
uniprot id: A0A2K8QPX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1778540:CVE23 RS10250
gene id: 1778540:CVE23_RS10250
uniprot id: A0A2K8QLR3
names: Similarity
messages: Belongs to the UPF0434 family.

1778540:CVE23 RS21230
gene id: 1778540:CVE23_RS21230
uniprot id: A0A2K8QT50
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1778540:CVE23 RS01380
gene id: 1778540:CVE23_RS01380
uniprot id: A0A2K8QGZ3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1778540:CVE23 RS21000
gene id: 1778540:CVE23_RS21000
uniprot id: A0A2K8QRW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS03490
gene id: 1778540:CVE23_RS03490
uniprot id: A0A2K8QHY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1778540:CVE23 RS18010
gene id: 1778540:CVE23_RS18010
uniprot id: A0A2K8QRJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1778540:CVE23 RS14730
gene id: 1778540:CVE23_RS14730
uniprot id: A0A2K8QP04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1778540:CVE23 RS10825
gene id: 1778540:CVE23_RS10825
uniprot id: A0A2K8QLN5
names: Similarity
messages: Belongs to the asparaginase 1 family.

1778540:CVE23 RS12115
gene id: 1778540:CVE23_RS12115
uniprot id: A0A2K8QNL2
names: Similarity
messages: Belongs to the FeoA family.

1778540:CVE23 RS04575
gene id: 1778540:CVE23_RS04575
uniprot id: A0A2K8QII5
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1778540:CVE23 RS14875
gene id: 1778540:CVE23_RS14875
uniprot id: A0A2K8QNP8
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1778540:CVE23 RS03270
gene id: 1778540:CVE23_RS03270
uniprot id: A0A2K8QHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1778540:CVE23 RS17940
gene id: 1778540:CVE23_RS17940
uniprot id: A0A2K8QQA8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1778540:CVE23 RS16725
gene id: 1778540:CVE23_RS16725
uniprot id: A0A2K8QTB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BtuF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1778540:CVE23 RS15170
gene id: 1778540:CVE23_RS15170
uniprot id: A0A2K8QNV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1778540:CVE23 RS05995
gene id: 1778540:CVE23_RS05995
uniprot id: A0A2K8QKL5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1778540:CVE23 RS21775
gene id: 1778540:CVE23_RS21775
uniprot id: A0A2K8QUD5
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS17780
gene id: 1778540:CVE23_RS17780
uniprot id: A0A2K8QQJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS01150
gene id: 1778540:CVE23_RS01150
uniprot id: A0A2K8QGR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS09720
gene id: 1778540:CVE23_RS09720
uniprot id: A0A2K8QL32
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1778540:CVE23 RS20890
gene id: 1778540:CVE23_RS20890
uniprot id: A0A2K8QS10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

1778540:CVE23 RS10615
gene id: 1778540:CVE23_RS10615
uniprot id: A0A2K8QLJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1778540:CVE23 RS19310
gene id: 1778540:CVE23_RS19310
uniprot id: A0A2K8QQY3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1778540:CVE23 RS18185
gene id: 1778540:CVE23_RS18185
uniprot id: A0A2K8QQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS17510
gene id: 1778540:CVE23_RS17510
uniprot id: A0A2K8QQ15
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS05785
gene id: 1778540:CVE23_RS05785
uniprot id: A0A2K8QJ51
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1778540:CVE23 RS06450
gene id: 1778540:CVE23_RS06450
uniprot id: A0A2K8QJJ7
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS01540
gene id: 1778540:CVE23_RS01540
uniprot id: A0A2K8QIA8
names: Similarity
messages: Belongs to the UPF0307 family.

1778540:CVE23 RS06625
gene id: 1778540:CVE23_RS06625
uniprot id: A0A2K8QJL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS10870
gene id: 1778540:CVE23_RS10870
uniprot id: A0A2K8QLN7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1778540:CVE23 RS19485
gene id: 1778540:CVE23_RS19485
uniprot id: A0A2K8QR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1778540:CVE23 RS02570
gene id: 1778540:CVE23_RS02570
uniprot id: A0A2K8QIT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1778540:CVE23 RS19060
gene id: 1778540:CVE23_RS19060
uniprot id: A0A2K8QQX2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS06210
gene id: 1778540:CVE23_RS06210
uniprot id: A0A2K8QJD1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1778540:CVE23 RS21220
gene id: 1778540:CVE23_RS21220
uniprot id: A0A2K8QS50
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS17735
gene id: 1778540:CVE23_RS17735
uniprot id: A0A2K8QTD2
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1778540:CVE23 RS17690
gene id: 1778540:CVE23_RS17690
uniprot id: A0A2K8QQ91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1778540:CVE23 RS04470
gene id: 1778540:CVE23_RS04470
uniprot id: A0A2K8QIN6
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

1778540:CVE23 RS20195
gene id: 1778540:CVE23_RS20195
uniprot id: A0A2K8QRG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1778540:CVE23 RS09905
gene id: 1778540:CVE23_RS09905
uniprot id: A0A2K8QL66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1778540:CVE23 RS17590
gene id: 1778540:CVE23_RS17590
uniprot id: A0A2K8QQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1778540:CVE23 RS05200
gene id: 1778540:CVE23_RS05200
uniprot id: A0A2K8QIV2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1778540:CVE23 RS16325
gene id: 1778540:CVE23_RS16325
uniprot id: A0A2K8QTE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1778540:CVE23 RS06915
gene id: 1778540:CVE23_RS06915
uniprot id: A0A2K8QJQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1778540:CVE23 RS09635
gene id: 1778540:CVE23_RS09635
uniprot id: A0A2K8QLC5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS16030
gene id: 1778540:CVE23_RS16030
uniprot id: A0A2K8QQM1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

1778540:CVE23 RS17210
gene id: 1778540:CVE23_RS17210
uniprot id: A0A2K8QR49
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS20375
gene id: 1778540:CVE23_RS20375
uniprot id: A0A2K8QRJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

1778540:CVE23 RS16355
gene id: 1778540:CVE23_RS16355
uniprot id: A0A2K8QPI8
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1778540:CVE23 RS19100
gene id: 1778540:CVE23_RS19100
uniprot id: A0A2K8QQV9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1778540:CVE23 RS14175
gene id: 1778540:CVE23_RS14175
uniprot id: A0A2K8QPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1778540:CVE23 RS06440
gene id: 1778540:CVE23_RS06440
uniprot id: A0A2K8QJR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1778540:CVE23 RS11500
gene id: 1778540:CVE23_RS11500
uniprot id: A0A2K8QM01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1778540:CVE23 RS11485
gene id: 1778540:CVE23_RS11485
uniprot id: A0A2K8QNB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1778540:CVE23 RS17680
gene id: 1778540:CVE23_RS17680
uniprot id: A0A2K8QQ51
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1778540:CVE23 RS00330
gene id: 1778540:CVE23_RS00330
uniprot id: A0A2K8QGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS16865
gene id: 1778540:CVE23_RS16865
uniprot id: A0A2K8QPR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1778540:CVE23 RS19925
gene id: 1778540:CVE23_RS19925
uniprot id: A0A2K8QRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

1778540:CVE23 RS03580
gene id: 1778540:CVE23_RS03580
uniprot id: A0A2K8QK84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1778540:CVE23 RS22235
gene id: 1778540:CVE23_RS22235
uniprot id: A0A2K8QUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system).

1778540:CVE23 RS13800
gene id: 1778540:CVE23_RS13800
uniprot id: A0A2K8QPK1
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

1778540:CVE23 RS11900
gene id: 1778540:CVE23_RS11900
uniprot id: A0A2K8QMA3
names: Similarity
messages: Belongs to the fructosamine kinase family.

1778540:CVE23 RS16380
gene id: 1778540:CVE23_RS16380
uniprot id: A0A2K8QPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1778540:CVE23 RS01695
gene id: 1778540:CVE23_RS01695
uniprot id: A0A2K8QID8
names: Similarity
messages: Belongs to the Gfa family.

1778540:CVE23 RS10395
gene id: 1778540:CVE23_RS10395
uniprot id: A0A2K8QLE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS21690
gene id: 1778540:CVE23_RS21690
uniprot id: A0A2K8QS81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS02100
gene id: 1778540:CVE23_RS02100
uniprot id: A0A2K8QHC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

1778540:CVE23 RS16920
gene id: 1778540:CVE23_RS16920
uniprot id: A0A2K8QQ68
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1778540:CVE23 RS19465
gene id: 1778540:CVE23_RS19465
uniprot id: A0A2K8QR16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1778540:CVE23 RS22490
gene id: 1778540:CVE23_RS22490
uniprot id: A0A2K8QSP2
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1778540:CVE23 RS03985
gene id: 1778540:CVE23_RS03985
uniprot id: A0A2K8QKG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1778540:CVE23 RS16395
gene id: 1778540:CVE23_RS16395
uniprot id: A0A2K8QPY7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1778540:CVE23 RS03400
gene id: 1778540:CVE23_RS03400
uniprot id: A0A2K8QHY2
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS21190
gene id: 1778540:CVE23_RS21190
uniprot id: A0A2K8QRZ6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1778540:CVE23 RS09725
gene id: 1778540:CVE23_RS09725
uniprot id: A0A2K8QNB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS20245
gene id: 1778540:CVE23_RS20245
uniprot id: A0A2K8QRH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1778540:CVE23 RS22125
gene id: 1778540:CVE23_RS22125
uniprot id: A0A2K8QSJ5
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

1778540:CVE23 RS01830
gene id: 1778540:CVE23_RS01830
uniprot id: A0A2K8QH25
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1778540:CVE23 RS00770
gene id: 1778540:CVE23_RS00770
uniprot id: A0A2K8QSM8
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS01675
gene id: 1778540:CVE23_RS01675
uniprot id: A0A2K8QH50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1778540:CVE23 RS15010
gene id: 1778540:CVE23_RS15010
uniprot id: A0A2K8QNW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

1778540:CVE23 RS13885
gene id: 1778540:CVE23_RS13885
uniprot id: A0A2K8QPF9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1778540:CVE23 RS17405
gene id: 1778540:CVE23_RS17405
uniprot id: A0A2K8QPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS04400
gene id: 1778540:CVE23_RS04400
uniprot id: A0A2K8QIF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1778540:CVE23 RS06305
gene id: 1778540:CVE23_RS06305
uniprot id: A0A2K8QJE4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS10640
gene id: 1778540:CVE23_RS10640
uniprot id: A0A2K8QLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

1778540:CVE23 RS10890
gene id: 1778540:CVE23_RS10890
uniprot id: A0A2K8QLQ6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1778540:CVE23 RS03285
gene id: 1778540:CVE23_RS03285
uniprot id: A0A2K8QHY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS03475
gene id: 1778540:CVE23_RS03475
uniprot id: A0A2K8QK63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1778540:CVE23 RS06845
gene id: 1778540:CVE23_RS06845
uniprot id: A0A2K8QJY6
names: Similarity
messages: Belongs to the citrate synthase family.

1778540:CVE23 RS09945
gene id: 1778540:CVE23_RS09945
uniprot id: A0A2K8QML8
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS13480
gene id: 1778540:CVE23_RS13480
uniprot id: A0A2K8QPD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

1778540:CVE23 RS19985
gene id: 1778540:CVE23_RS19985
uniprot id: A0A2K8QRC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS14325
gene id: 1778540:CVE23_RS14325
uniprot id: A0A2K8QNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS04460
gene id: 1778540:CVE23_RS04460
uniprot id: A0A2K8QKQ1
names: Similarity
messages: Belongs to the UPF0178 family.

1778540:CVE23 RS16575
gene id: 1778540:CVE23_RS16575
uniprot id: A0A2K8QPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1778540:CVE23 RS21990
gene id: 1778540:CVE23_RS21990
uniprot id: A0A2K8QSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS05425
gene id: 1778540:CVE23_RS05425
uniprot id: A0A2K8QIY3
names: Similarity
messages: Belongs to the skp family.

1778540:CVE23 RS18900
gene id: 1778540:CVE23_RS18900
uniprot id: A0A2K8QQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

1778540:CVE23 RS10105
gene id: 1778540:CVE23_RS10105
uniprot id: A0A2K8QLB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1778540:CVE23 RS03640
gene id: 1778540:CVE23_RS03640
uniprot id: A0A2K8QI18
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1778540:CVE23 RS22060
gene id: 1778540:CVE23_RS22060
uniprot id: A0A2K8QSE4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1778540:CVE23 RS21620
gene id: 1778540:CVE23_RS21620
uniprot id: A0A2K8QUB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

1778540:CVE23 RS20485
gene id: 1778540:CVE23_RS20485
uniprot id: A0A2K8QTP6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1778540:CVE23 RS02145
gene id: 1778540:CVE23_RS02145
uniprot id: A0A2K8QH88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1778540:CVE23 RS03550
gene id: 1778540:CVE23_RS03550
uniprot id: A0A2K8QI32
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1778540:CVE23 RS15195
gene id: 1778540:CVE23_RS15195
uniprot id: A0A2K8QNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS11230
gene id: 1778540:CVE23_RS11230
uniprot id: A0A2K8QNA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1778540:CVE23 RS13325
gene id: 1778540:CVE23_RS13325
uniprot id: A0A2K8QQ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS21585
gene id: 1778540:CVE23_RS21585
uniprot id: A0A2K8QS54
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1778540:CVE23 RS12250
gene id: 1778540:CVE23_RS12250
uniprot id: A0A2K8QPM3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1778540:CVE23 RS10925
gene id: 1778540:CVE23_RS10925
uniprot id: A0A2K8QNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1778540:CVE23 RS11125
gene id: 1778540:CVE23_RS11125
uniprot id: A0A2K8QN85
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1778540:CVE23 RS09300
gene id: 1778540:CVE23_RS09300
uniprot id: A0A2K8QKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS20135
gene id: 1778540:CVE23_RS20135
uniprot id: A0A2K8QRM0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1778540:CVE23 RS04615
gene id: 1778540:CVE23_RS04615
uniprot id: A0A2K8QIJ0
names: Subcellular Location Annotation
messages: Cell inner membrane

1778540:CVE23 RS03280
gene id: 1778540:CVE23_RS03280
uniprot id: A0A2K8QHU6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1778540:CVE23 RS12165
gene id: 1778540:CVE23_RS12165
uniprot id: A0A2K8QMD4
names: Subcellular Location Annotation
messages: Secreted

1778540:CVE23 RS14230
gene id: 1778540:CVE23_RS14230
uniprot id: A0A2K8QNH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1778540:CVE23 RS07835
gene id: 1778540:CVE23_RS07835
uniprot id: A0A2K8QK38
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS14865
gene id: 1778540:CVE23_RS14865
uniprot id: A0A2K8QNP6
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS14760
gene id: 1778540:CVE23_RS14760
uniprot id: A0A2K8QNM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1778540:CVE23 RS14110
gene id: 1778540:CVE23_RS14110
uniprot id: A0A2K8QNP0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1778540:CVE23 RS22440
gene id: 1778540:CVE23_RS22440
uniprot id: A0A2K8QSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

1778540:CVE23 RS17455
gene id: 1778540:CVE23_RS17455
uniprot id: A0A2K8QPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1778540:CVE23 RS10080
gene id: 1778540:CVE23_RS10080
uniprot id: A0A2K8QLA4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1778540:CVE23 RS16295
gene id: 1778540:CVE23_RS16295
uniprot id: A0A2K8QPH8
names: Similarity
messages: Belongs to the YfgM family.

1778540:CVE23 RS17190
gene id: 1778540:CVE23_RS17190
uniprot id: A0A2K8QQA7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1778540:CVE23 RS14940
gene id: 1778540:CVE23_RS14940
uniprot id: A0A2K8QR31
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1778540:CVE23 RS13170
gene id: 1778540:CVE23_RS13170
uniprot id: A0A2K8QU93
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

1778540:CVE23 RS20210
gene id: 1778540:CVE23_RS20210
uniprot id: A0A2K8QRF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1778540:CVE23 RS06760
gene id: 1778540:CVE23_RS06760
uniprot id: A0A2K8QKV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

1778540:CVE23 RS01725
gene id: 1778540:CVE23_RS01725
uniprot id: A0A2K8QH10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1778540:CVE23 RS13980
gene id: 1778540:CVE23_RS13980
uniprot id: A0A2K8QNA6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1778540:CVE23 RS05865
gene id: 1778540:CVE23_RS05865
uniprot id: A0A2K8QJ60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1778540:CVE23 RS15220
gene id: 1778540:CVE23_RS15220
uniprot id: A0A2K8QNW1
names: Similarity
messages: Belongs to the GSP C family.

1778540:CVE23 RS11490
gene id: 1778540:CVE23_RS11490
uniprot id: A0A2K8QM19
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1778540:CVE23 RS06910
gene id: 1778540:CVE23_RS06910
uniprot id: A0A2K8QKZ1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1778540:CVE23 RS19185
gene id: 1778540:CVE23_RS19185
uniprot id: A0A2K8QR30
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1778540:CVE23 RS06570
gene id: 1778540:CVE23_RS06570
uniprot id: A0A2K8QJI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1778540:CVE23 RS15335
gene id: 1778540:CVE23_RS15335
uniprot id: A0A2K8QNY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1778540:CVE23 RS09610
gene id: 1778540:CVE23_RS09610
uniprot id: A0A2K8QMF5
names: Similarity
messages: Belongs to the elongation factor P family.

1778540:CVE23 RS07135
gene id: 1778540:CVE23_RS07135
uniprot id: A0A2K8QK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS06325
gene id: 1778540:CVE23_RS06325
uniprot id: A0A2K8QJH5
names: Similarity
messages: Belongs to the CinA family.

1778540:CVE23 RS09580
gene id: 1778540:CVE23_RS09580
uniprot id: A0A2K8QLB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS17505
gene id: 1778540:CVE23_RS17505
uniprot id: A0A2K8QR93
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1778540:CVE23 RS03340
gene id: 1778540:CVE23_RS03340
uniprot id: A0A2K8QJ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS11095
gene id: 1778540:CVE23_RS11095
uniprot id: A0A2K8QM60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1778540:CVE23 RS06460
gene id: 1778540:CVE23_RS06460
uniprot id: A0A2K8QJH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1778540:CVE23 RS00080
gene id: 1778540:CVE23_RS00080
uniprot id: A0A2K8QGC3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1778540:CVE23 RS06740
gene id: 1778540:CVE23_RS06740
uniprot id: A0A2K8QJP2
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1778540:CVE23 RS20450
gene id: 1778540:CVE23_RS20450
uniprot id: A0A2K8QRL5
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS04790
gene id: 1778540:CVE23_RS04790
uniprot id: A0A2K8QIQ8
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1778540:CVE23 RS06865
gene id: 1778540:CVE23_RS06865
uniprot id: A0A2K8QJP9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1778540:CVE23 RS19325
gene id: 1778540:CVE23_RS19325
uniprot id: A0A2K8QTF0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1778540:CVE23 RS19905
gene id: 1778540:CVE23_RS19905
uniprot id: A0A2K8QRA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

1778540:CVE23 RS19420
gene id: 1778540:CVE23_RS19420
uniprot id: A0A2K8QT46
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1778540:CVE23 RS16870
gene id: 1778540:CVE23_RS16870
uniprot id: A0A2K8QPS2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1778540:CVE23 RS20340
gene id: 1778540:CVE23_RS20340
uniprot id: A0A2K8QRJ5
names: Similarity
messages: Belongs to the SlyX family.

1778540:CVE23 RS20015
gene id: 1778540:CVE23_RS20015
uniprot id: A0A2K8QRI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1778540:CVE23 RS17905
gene id: 1778540:CVE23_RS17905
uniprot id: A0A2K8QTG0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1778540:CVE23 RS18930
gene id: 1778540:CVE23_RS18930
uniprot id: A0A2K8QR42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1778540:CVE23 RS09065
gene id: 1778540:CVE23_RS09065
uniprot id: A0A2K8QKQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1778540:CVE23 RS22215
gene id: 1778540:CVE23_RS22215
uniprot id: A0A2K8QSG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1778540:CVE23 RS09860
gene id: 1778540:CVE23_RS09860
uniprot id: A0A2K8QL89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1778540:CVE23 RS00790
gene id: 1778540:CVE23_RS00790
uniprot id: A0A2K8QHT6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1778540:CVE23 RS22275
gene id: 1778540:CVE23_RS22275
uniprot id: A0A2K8QSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1778540:CVE23 RS03405
gene id: 1778540:CVE23_RS03405
uniprot id: A0A2K8QHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1778540:CVE23 RS02610
gene id: 1778540:CVE23_RS02610
uniprot id: A0A2K8QIQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1778540:CVE23 RS12760
gene id: 1778540:CVE23_RS12760
uniprot id: A0A2K8QN03
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1778540:CVE23 RS17860
gene id: 1778540:CVE23_RS17860
uniprot id: A0A2K8QQD1
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1778540:CVE23 RS16565
gene id: 1778540:CVE23_RS16565
uniprot id: A0A2K8QPM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1778540:CVE23 RS02095
gene id: 1778540:CVE23_RS02095
uniprot id: A0A2K8QH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1778540:CVE23 RS08550
gene id: 1778540:CVE23_RS08550
uniprot id: A0A2K8QKI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1778540:CVE23 RS21465
gene id: 1778540:CVE23_RS21465
uniprot id: A0A2K8QS44
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1778540:CVE23 RS05400
gene id: 1778540:CVE23_RS05400
uniprot id: A0A2K8QKA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

1778540:CVE23 RS08595
gene id: 1778540:CVE23_RS08595
uniprot id: A0A2K8QLS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1778540:CVE23 RS10185
gene id: 1778540:CVE23_RS10185
uniprot id: A0A2K8QLQ3
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS19565
gene id: 1778540:CVE23_RS19565
uniprot id: A0A2K8QR97
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1778540:CVE23 RS14080
gene id: 1778540:CVE23_RS14080
uniprot id: A0A2K8QT84
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1778540:CVE23 RS22140
gene id: 1778540:CVE23_RS22140
uniprot id: A0A2K8QSF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1778540:CVE23 RS06655
gene id: 1778540:CVE23_RS06655
uniprot id: A0A2K8QSY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1778540:CVE23 RS05125
gene id: 1778540:CVE23_RS05125
uniprot id: A0A2K8QJ11
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1778540:CVE23 RS16545
gene id: 1778540:CVE23_RS16545
uniprot id: A0A2K8QRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1778540:CVE23 RS06525
gene id: 1778540:CVE23_RS06525
uniprot id: A0A2K8QJI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

1778540:CVE23 RS03630
gene id: 1778540:CVE23_RS03630
uniprot id: A0A2K8QI14
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

1778540:CVE23 RS22055
gene id: 1778540:CVE23_RS22055
uniprot id: A0A2K8QUI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1778540:CVE23 RS05815
gene id: 1778540:CVE23_RS05815
uniprot id: A0A2K8QJ83
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1778540:CVE23 RS10810
gene id: 1778540:CVE23_RS10810
uniprot id: A0A2K8QU67
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1778540:CVE23 RS10175
gene id: 1778540:CVE23_RS10175
uniprot id: A0A2K8QNL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

1778540:CVE23 RS21125
gene id: 1778540:CVE23_RS21125
uniprot id: A0A2K8QT37
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1778540:CVE23 RS09025
gene id: 1778540:CVE23_RS09025
uniprot id: A0A2K8QKT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1778540:CVE23 RS12070
gene id: 1778540:CVE23_RS12070
uniprot id: A0A2K8QMA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1778540:CVE23 RS13515
gene id: 1778540:CVE23_RS13515
uniprot id: A0A2K8QPA0
names: Similarity
messages: Belongs to the HesB/IscA family.

1778540:CVE23 RS21875
gene id: 1778540:CVE23_RS21875
uniprot id: A0A2K8QSD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

1778540:CVE23 RS20260
gene id: 1778540:CVE23_RS20260
uniprot id: A0A2K8QRH8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1778540:CVE23 RS01160
gene id: 1778540:CVE23_RS01160
uniprot id: A0A2K8QHZ4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1778540:CVE23 RS13805
gene id: 1778540:CVE23_RS13805
uniprot id: A0A2K8QN58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoB family.
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

1778540:CVE23 RS11575
gene id: 1778540:CVE23_RS11575
uniprot id: A0A2K8QPA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1778540:CVE23 RS14635
gene id: 1778540:CVE23_RS14635
uniprot id: A0A2K8QNL3
names: Similarity
messages: Belongs to the HypD family.

1778540:CVE23 RS12860
gene id: 1778540:CVE23_RS12860
uniprot id: A0A2K8QMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS06250
gene id: 1778540:CVE23_RS06250
uniprot id: A0A2K8QJD4
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1778540:CVE23 RS01270
gene id: 1778540:CVE23_RS01270
uniprot id: A0A2K8QGU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1778540:CVE23 RS16450
gene id: 1778540:CVE23_RS16450
uniprot id: A0A2K8QPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1778540:CVE23 RS16815
gene id: 1778540:CVE23_RS16815
uniprot id: A0A2K8QQY4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1778540:CVE23 RS12405
gene id: 1778540:CVE23_RS12405
uniprot id: A0A2K8QNV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS17450
gene id: 1778540:CVE23_RS17450
uniprot id: A0A2K8QR83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS05965
gene id: 1778540:CVE23_RS05965
uniprot id: A0A2K8QJH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1778540:CVE23 RS11815
gene id: 1778540:CVE23_RS11815
uniprot id: A0A2K8QNJ8
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1778540:CVE23 RS18350
gene id: 1778540:CVE23_RS18350
uniprot id: A0A2K8QQF7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1778540:CVE23 RS12535
gene id: 1778540:CVE23_RS12535
uniprot id: A0A2K8QPT4
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS17200
gene id: 1778540:CVE23_RS17200
uniprot id: A0A2K8QPW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1778540:CVE23 RS10900
gene id: 1778540:CVE23_RS10900
uniprot id: A0A2K8QN02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1778540:CVE23 RS19385
gene id: 1778540:CVE23_RS19385
uniprot id: A0A2K8QR18
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1778540:CVE23 RS21440
gene id: 1778540:CVE23_RS21440
uniprot id: A0A2K8QSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS21560
gene id: 1778540:CVE23_RS21560
uniprot id: A0A2K8QTB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

1778540:CVE23 RS04800
gene id: 1778540:CVE23_RS04800
uniprot id: A0A2K8QIM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS16500
gene id: 1778540:CVE23_RS16500
uniprot id: A0A2K8QQ06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1778540:CVE23 RS18340
gene id: 1778540:CVE23_RS18340
uniprot id: A0A2K8QQF8
names: Similarity
messages: Belongs to the UPF0047 family.

1778540:CVE23 RS22050
gene id: 1778540:CVE23_RS22050
uniprot id: A0A2K8QSF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1778540:CVE23 RS06895
gene id: 1778540:CVE23_RS06895
uniprot id: A0A2K8QJZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1778540:CVE23 RS06335
gene id: 1778540:CVE23_RS06335
uniprot id: A0A2K8QJE5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1778540:CVE23 RS16800
gene id: 1778540:CVE23_RS16800
uniprot id: A0A2K8QQ48
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1778540:CVE23 RS00995
gene id: 1778540:CVE23_RS00995
uniprot id: A0A2K8QGT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS08955
gene id: 1778540:CVE23_RS08955
uniprot id: A0A2K8QKP0
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS09005
gene id: 1778540:CVE23_RS09005
uniprot id: A0A2K8QKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1778540:CVE23 RS03990
gene id: 1778540:CVE23_RS03990
uniprot id: A0A2K8QIB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1778540:CVE23 RS22460
gene id: 1778540:CVE23_RS22460
uniprot id: A0A2K8QSN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

1778540:CVE23 RS09195
gene id: 1778540:CVE23_RS09195
uniprot id: A0A2K8QKW3
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1778540:CVE23 RS15375
gene id: 1778540:CVE23_RS15375
uniprot id: A0A2K8QP22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

1778540:CVE23 RS12835
gene id: 1778540:CVE23_RS12835
uniprot id: A0A2K8QMR3
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS14740
gene id: 1778540:CVE23_RS14740
uniprot id: A0A2K8QNN1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1778540:CVE23 RS05960
gene id: 1778540:CVE23_RS05960
uniprot id: A0A2K8QT19
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1778540:CVE23 RS14845
gene id: 1778540:CVE23_RS14845
uniprot id: A0A2K8QNQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1778540:CVE23 RS05440
gene id: 1778540:CVE23_RS05440
uniprot id: A0A2K8QIZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1778540:CVE23 RS04435
gene id: 1778540:CVE23_RS04435
uniprot id: A0A2K8QIG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1778540:CVE23 RS05940
gene id: 1778540:CVE23_RS05940
uniprot id: A0A2K8QKK5
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS05215
gene id: 1778540:CVE23_RS05215
uniprot id: A0A2K8QK79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS01115
gene id: 1778540:CVE23_RS01115
uniprot id: A0A2K8QIY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1778540:CVE23 RS14915
gene id: 1778540:CVE23_RS14915
uniprot id: A0A2K8QPZ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1778540:CVE23 RS12730
gene id: 1778540:CVE23_RS12730
uniprot id: A0A2K8QP16
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS21845
gene id: 1778540:CVE23_RS21845
uniprot id: A0A2K8QSE6
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1778540:CVE23 RS20235
gene id: 1778540:CVE23_RS20235
uniprot id: A0A2K8QRP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1778540:CVE23 RS02550
gene id: 1778540:CVE23_RS02550
uniprot id: A0A2K8QHK7
names: Similarity
messages: Belongs to the Smp family.

1778540:CVE23 RS06115
gene id: 1778540:CVE23_RS06115
uniprot id: A0A2K8QJD6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1778540:CVE23 RS20305
gene id: 1778540:CVE23_RS20305
uniprot id: A0A2K8QRN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

1778540:CVE23 RS01550
gene id: 1778540:CVE23_RS01550
uniprot id: A0A2K8QJ52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

1778540:CVE23 RS06455
gene id: 1778540:CVE23_RS06455
uniprot id: A0A2K8QKR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1778540:CVE23 RS08995
gene id: 1778540:CVE23_RS08995
uniprot id: A0A2K8QLZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1778540:CVE23 RS20970
gene id: 1778540:CVE23_RS20970
uniprot id: A0A2K8QSZ7
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS20285
gene id: 1778540:CVE23_RS20285
uniprot id: A0A2K8QRQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1778540:CVE23 RS21115
gene id: 1778540:CVE23_RS21115
uniprot id: A0A2K8QRY0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1778540:CVE23 RS16570
gene id: 1778540:CVE23_RS16570
uniprot id: A0A2K8QQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1778540:CVE23 RS18805
gene id: 1778540:CVE23_RS18805
uniprot id: A0A2K8QQP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1778540:CVE23 RS00765
gene id: 1778540:CVE23_RS00765
uniprot id: A0A2K8QGP6
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS15460
gene id: 1778540:CVE23_RS15460
uniprot id: A0A2K8QP01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS21325
gene id: 1778540:CVE23_RS21325
uniprot id: A0A2K8QS20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1778540:CVE23 RS03530
gene id: 1778540:CVE23_RS03530
uniprot id: A0A2K8QK73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1778540:CVE23 RS06150
gene id: 1778540:CVE23_RS06150
uniprot id: A0A2K8QKP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS11990
gene id: 1778540:CVE23_RS11990
uniprot id: A0A2K8QM98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1778540:CVE23 RS13915
gene id: 1778540:CVE23_RS13915
uniprot id: A0A2K8QQH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1778540:CVE23 RS14025
gene id: 1778540:CVE23_RS14025
uniprot id: A0A2K8QNC4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1778540:CVE23 RS20820
gene id: 1778540:CVE23_RS20820
uniprot id: A0A2K8QS09
names: Similarity
messages: Belongs to the Rht family.

1778540:CVE23 RS10135
gene id: 1778540:CVE23_RS10135
uniprot id: A0A2K8QLP0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

1778540:CVE23 RS17215
gene id: 1778540:CVE23_RS17215
uniprot id: A0A2K8QQ00
names: Similarity
messages: Belongs to the YciI family.

1778540:CVE23 RS08735
gene id: 1778540:CVE23_RS08735
uniprot id: A0A2K8QMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS13165
gene id: 1778540:CVE23_RS13165
uniprot id: A0A2K8QMV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS11520
gene id: 1778540:CVE23_RS11520
uniprot id: A0A2K8QP95
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1778540:CVE23 RS21750
gene id: 1778540:CVE23_RS21750
uniprot id: A0A2K8QTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS20660
gene id: 1778540:CVE23_RS20660
uniprot id: A0A2K8QRX7
names: Similarity
messages: Belongs to the DapA family.

1778540:CVE23 RS16260
gene id: 1778540:CVE23_RS16260
uniprot id: A0A2K8QPG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1778540:CVE23 RS07105
gene id: 1778540:CVE23_RS07105
uniprot id: A0A2K8QU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1778540:CVE23 RS06970
gene id: 1778540:CVE23_RS06970
uniprot id: A0A2K8QK05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1778540:CVE23 RS20830
gene id: 1778540:CVE23_RS20830
uniprot id: A0A2K8QRT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1778540:CVE23 RS11830
gene id: 1778540:CVE23_RS11830
uniprot id: A0A2K8QM72
names: Similarity
messages: Belongs to the UPF0181 family.

1778540:CVE23 RS00555
gene id: 1778540:CVE23_RS00555
uniprot id: A0A2K8QGK9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1778540:CVE23 RS03755
gene id: 1778540:CVE23_RS03755
uniprot id: A0A2K8QI35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS06425
gene id: 1778540:CVE23_RS06425
uniprot id: A0A2K8QJG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1778540:CVE23 RS19660
gene id: 1778540:CVE23_RS19660
uniprot id: A0A2K8QR74
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1778540:CVE23 RS07035
gene id: 1778540:CVE23_RS07035
uniprot id: A0A2K8QJU2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1778540:CVE23 RS08160
gene id: 1778540:CVE23_RS08160
uniprot id: A0A2K8QKK6
names: Similarity
messages: Belongs to the HupF/HypC family.

1778540:CVE23 RS19200
gene id: 1778540:CVE23_RS19200
uniprot id: A0A2K8QS27
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1778540:CVE23 RS18770
gene id: 1778540:CVE23_RS18770
uniprot id: A0A2K8QTE4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1778540:CVE23 RS11080
gene id: 1778540:CVE23_RS11080
uniprot id: A0A2K8QLR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1778540:CVE23 RS14205
gene id: 1778540:CVE23_RS14205
uniprot id: A0A2K8QNF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1778540:CVE23 RS17280
gene id: 1778540:CVE23_RS17280
uniprot id: A0A2K8QPX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1778540:CVE23 RS16290
gene id: 1778540:CVE23_RS16290
uniprot id: A0A2K8QPF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1778540:CVE23 RS18540
gene id: 1778540:CVE23_RS18540
uniprot id: A0A2K8QSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS10840
gene id: 1778540:CVE23_RS10840
uniprot id: A0A2K8QLR0
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1778540:CVE23 RS12910
gene id: 1778540:CVE23_RS12910
uniprot id: A0A2K8QPZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1778540:CVE23 RS22130
gene id: 1778540:CVE23_RS22130
uniprot id: A0A2K8QTK9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1778540:CVE23 RS09660
gene id: 1778540:CVE23_RS09660
uniprot id: A0A2K8QL15
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS12000
gene id: 1778540:CVE23_RS12000
uniprot id: A0A2K8QMA6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1778540:CVE23 RS10005
gene id: 1778540:CVE23_RS10005
uniprot id: A0A2K8QNG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1778540:CVE23 RS13270
gene id: 1778540:CVE23_RS13270
uniprot id: A0A2K8QQ56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1778540:CVE23 RS10780
gene id: 1778540:CVE23_RS10780
uniprot id: A0A2K8QLP1
names: Similarity
messages: Belongs to the UPF0229 family.

1778540:CVE23 RS01685
gene id: 1778540:CVE23_RS01685
uniprot id: A0A2K8QH08
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1778540:CVE23 RS19410
gene id: 1778540:CVE23_RS19410
uniprot id: A0A2K8QS63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1778540:CVE23 RS06555
gene id: 1778540:CVE23_RS06555
uniprot id: A0A2K8QJL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1778540:CVE23 RS02495
gene id: 1778540:CVE23_RS02495
uniprot id: A0A2K8QHJ8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1778540:CVE23 RS12015
gene id: 1778540:CVE23_RS12015
uniprot id: A0A2K8QMB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1778540:CVE23 RS06385
gene id: 1778540:CVE23_RS06385
uniprot id: A0A2K8QJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1778540:CVE23 RS00255
gene id: 1778540:CVE23_RS00255
uniprot id: A0A2K8QHJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS03720
gene id: 1778540:CVE23_RS03720
uniprot id: A0A2K8QI62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1778540:CVE23 RS05355
gene id: 1778540:CVE23_RS05355
uniprot id: A0A2K8QL39
names: Similarity
messages: Belongs to the UPF0325 family.

1778540:CVE23 RS06020
gene id: 1778540:CVE23_RS06020
uniprot id: A0A2K8QJ88
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1778540:CVE23 RS00955
gene id: 1778540:CVE23_RS00955
uniprot id: A0A2K8QGN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1778540:CVE23 RS06765
gene id: 1778540:CVE23_RS06765
uniprot id: A0A2K8QJM8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1778540:CVE23 RS06535
gene id: 1778540:CVE23_RS06535
uniprot id: A0A2K8QSV4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1778540:CVE23 RS01810
gene id: 1778540:CVE23_RS01810
uniprot id: A0A2K8QH41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1778540:CVE23 RS03685
gene id: 1778540:CVE23_RS03685
uniprot id: A0A2K8QI25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1778540:CVE23 RS12745
gene id: 1778540:CVE23_RS12745
uniprot id: A0A2K8QML6
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1778540:CVE23 RS16730
gene id: 1778540:CVE23_RS16730
uniprot id: A0A2K8QPM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1778540:CVE23 RS11330
gene id: 1778540:CVE23_RS11330
uniprot id: A0A2K8QLZ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10B family.
messages: Binds 1 zinc ion per subunit.

1778540:CVE23 RS05880
gene id: 1778540:CVE23_RS05880
uniprot id: A0A2K8QJ70
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1778540:CVE23 RS07685
gene id: 1778540:CVE23_RS07685
uniprot id: A0A2K8QKC3
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS01680
gene id: 1778540:CVE23_RS01680
uniprot id: A0A2K8QI82
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1778540:CVE23 RS20925
gene id: 1778540:CVE23_RS20925
uniprot id: A0A2K8QRV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS13855
gene id: 1778540:CVE23_RS13855
uniprot id: A0A2K8QN68
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1778540:CVE23 RS01280
gene id: 1778540:CVE23_RS01280
uniprot id: A0A2K8QI69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

1778540:CVE23 RS20215
gene id: 1778540:CVE23_RS20215
uniprot id: A0A2K8QSJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1778540:CVE23 RS20850
gene id: 1778540:CVE23_RS20850
uniprot id: A0A2K8QSX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1778540:CVE23 RS21275
gene id: 1778540:CVE23_RS21275
uniprot id: A0A2K8QS64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1778540:CVE23 RS20365
gene id: 1778540:CVE23_RS20365
uniprot id: A0A2K8QRJ9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1778540:CVE23 RS12210
gene id: 1778540:CVE23_RS12210
uniprot id: A0A2K8QMQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

1778540:CVE23 RS00810
gene id: 1778540:CVE23_RS00810
uniprot id: A0A2K8QGM1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1778540:CVE23 RS08215
gene id: 1778540:CVE23_RS08215
uniprot id: A0A2K8QKL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS09620
gene id: 1778540:CVE23_RS09620
uniprot id: A0A2K8QL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

1778540:CVE23 RS15015
gene id: 1778540:CVE23_RS15015
uniprot id: A0A2K8QQ13
names: Similarity
messages: Belongs to the UPF0381 family.

1778540:CVE23 RS21025
gene id: 1778540:CVE23_RS21025
uniprot id: A0A2K8QRY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1778540:CVE23 RS07870
gene id: 1778540:CVE23_RS07870
uniprot id: A0A2K8QK86
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS21665
gene id: 1778540:CVE23_RS21665
uniprot id: A0A2K8QTD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1778540:CVE23 RS13895
gene id: 1778540:CVE23_RS13895
uniprot id: A0A2K8QU99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1778540:CVE23 RS10415
gene id: 1778540:CVE23_RS10415
uniprot id: A0A2K8QLF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1778540:CVE23 RS05430
gene id: 1778540:CVE23_RS05430
uniprot id: A0A2K8QJ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1778540:CVE23 RS00945
gene id: 1778540:CVE23_RS00945
uniprot id: A0A2K8QGS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

1778540:CVE23 RS17475
gene id: 1778540:CVE23_RS17475
uniprot id: A0A2K8QQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS20165
gene id: 1778540:CVE23_RS20165
uniprot id: A0A2K8QSI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1778540:CVE23 RS01365
gene id: 1778540:CVE23_RS01365
uniprot id: A0A2K8QUT3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1778540:CVE23 RS13790
gene id: 1778540:CVE23_RS13790
uniprot id: A0A2K8QN92
names: Similarity
messages: Belongs to the UPF0227 family.

1778540:CVE23 RS20145
gene id: 1778540:CVE23_RS20145
uniprot id: A0A2K8QRF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1778540:CVE23 RS14955
gene id: 1778540:CVE23_RS14955
uniprot id: A0A2K8QNS0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1778540:CVE23 RS14040
gene id: 1778540:CVE23_RS14040
uniprot id: A0A2K8QNB5
names: Similarity
messages: Belongs to the PhoH family.

1778540:CVE23 RS15190
gene id: 1778540:CVE23_RS15190
uniprot id: A0A2K8QNW0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1778540:CVE23 RS11325
gene id: 1778540:CVE23_RS11325
uniprot id: A0A2K8QN82
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10B family.
messages: Binds 1 zinc ion per subunit.

1778540:CVE23 RS17120
gene id: 1778540:CVE23_RS17120
uniprot id: A0A2K8QPX8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1778540:CVE23 RS06650
gene id: 1778540:CVE23_RS06650
uniprot id: A0A2K8QJN3
names: Similarity
messages: Belongs to the PhoH family.

1778540:CVE23 RS19535
gene id: 1778540:CVE23_RS19535
uniprot id: A0A2K8QR43
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.

1778540:CVE23 RS09950
gene id: 1778540:CVE23_RS09950
uniprot id: A0A2K8QL70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1778540:CVE23 RS21755
gene id: 1778540:CVE23_RS21755
uniprot id: A0A2K8QSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS02605
gene id: 1778540:CVE23_RS02605
uniprot id: A0A2K8QHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1778540:CVE23 RS09135
gene id: 1778540:CVE23_RS09135
uniprot id: A0A2K8QN04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS02720
gene id: 1778540:CVE23_RS02720
uniprot id: A0A2K8QTV9
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.

1778540:CVE23 RS09895
gene id: 1778540:CVE23_RS09895
uniprot id: A0A2K8QL60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS00100
gene id: 1778540:CVE23_RS00100
uniprot id: A0A2K8QHG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS06935
gene id: 1778540:CVE23_RS06935
uniprot id: A0A2K8QLX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1778540:CVE23 RS14350
gene id: 1778540:CVE23_RS14350
uniprot id: A0A2K8QNF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

1778540:CVE23 RS09630
gene id: 1778540:CVE23_RS09630
uniprot id: A0A2K8QL17
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1778540:CVE23 RS21870
gene id: 1778540:CVE23_RS21870
uniprot id: A0A2K8QUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS17795
gene id: 1778540:CVE23_RS17795
uniprot id: A0A2K8QRE3
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS21195
gene id: 1778540:CVE23_RS21195
uniprot id: A0A2K8QS70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS03315
gene id: 1778540:CVE23_RS03315
uniprot id: A0A2K8QK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1778540:CVE23 RS09665
gene id: 1778540:CVE23_RS09665
uniprot id: A0A2K8QMG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

1778540:CVE23 RS10000
gene id: 1778540:CVE23_RS10000
uniprot id: A0A2K8QL80
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1778540:CVE23 RS14105
gene id: 1778540:CVE23_RS14105
uniprot id: A0A2K8QND3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliT family.
messages: Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
messages: Homodimer. Interacts with FliD and FlhC.
messages: cytosol

1778540:CVE23 RS21760
gene id: 1778540:CVE23_RS21760
uniprot id: A0A2K8QS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1778540:CVE23 RS18740
gene id: 1778540:CVE23_RS18740
uniprot id: A0A2K8QQN1
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1778540:CVE23 RS01010
gene id: 1778540:CVE23_RS01010
uniprot id: A0A2K8QGT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1778540:CVE23 RS19805
gene id: 1778540:CVE23_RS19805
uniprot id: A0A2K8QR98
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1778540:CVE23 RS12110
gene id: 1778540:CVE23_RS12110
uniprot id: A0A2K8QME2
names: Similarity
messages: Belongs to the FeoA family.

1778540:CVE23 RS11085
gene id: 1778540:CVE23_RS11085
uniprot id: A0A2K8QP23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS15965
gene id: 1778540:CVE23_RS15965
uniprot id: A0A2K8QPA1
names: Subcellular Location Annotation
messages: Cell inner membrane

1778540:CVE23 RS20190
gene id: 1778540:CVE23_RS20190
uniprot id: A0A2K8QRF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1778540:CVE23 RS04510
gene id: 1778540:CVE23_RS04510
uniprot id: A0A2K8QIH5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1778540:CVE23 RS18890
gene id: 1778540:CVE23_RS18890
uniprot id: A0A2K8QQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1778540:CVE23 RS06530
gene id: 1778540:CVE23_RS06530
uniprot id: A0A2K8QLP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1778540:CVE23 RS03655
gene id: 1778540:CVE23_RS03655
uniprot id: A0A2K8QI89
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1778540:CVE23 RS04640
gene id: 1778540:CVE23_RS04640
uniprot id: A0A2K8QIR7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1778540:CVE23 RS19005
gene id: 1778540:CVE23_RS19005
uniprot id: A0A2K8QRZ8
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

1778540:CVE23 RS01000
gene id: 1778540:CVE23_RS01000
uniprot id: A0A2K8QGW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1778540:CVE23 RS06300
gene id: 1778540:CVE23_RS06300
uniprot id: A0A2K8QJE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1778540:CVE23 RS03625
gene id: 1778540:CVE23_RS03625
uniprot id: A0A2K8QSZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1778540:CVE23 RS04770
gene id: 1778540:CVE23_RS04770
uniprot id: A0A2K8QK04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS10620
gene id: 1778540:CVE23_RS10620
uniprot id: A0A2K8QLX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1778540:CVE23 RS03505
gene id: 1778540:CVE23_RS03505
uniprot id: A0A2K8QI02
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1778540:CVE23 RS08910
gene id: 1778540:CVE23_RS08910
uniprot id: A0A2K8QKR0
names: Similarity
messages: Belongs to the flavodoxin family.

1778540:CVE23 RS17960
gene id: 1778540:CVE23_RS17960
uniprot id: A0A2K8QRI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1778540:CVE23 RS20280
gene id: 1778540:CVE23_RS20280
uniprot id: A0A2K8QGY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1778540:CVE23 RS16255
gene id: 1778540:CVE23_RS16255
uniprot id: A0A2K8QPJ2
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1778540:CVE23 RS15935
gene id: 1778540:CVE23_RS15935
uniprot id: A0A2K8QP90
names: Similarity
messages: Belongs to the acylphosphatase family.

1778540:CVE23 RS13560
gene id: 1778540:CVE23_RS13560
uniprot id: A0A2K8QN24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

1778540:CVE23 RS22115
gene id: 1778540:CVE23_RS22115
uniprot id: A0A2K8QSQ3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1778540:CVE23 RS06430
gene id: 1778540:CVE23_RS06430
uniprot id: A0A2K8QLM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

1778540:CVE23 RS21265
gene id: 1778540:CVE23_RS21265
uniprot id: A0A2K8QS08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.

1778540:CVE23 RS14195
gene id: 1778540:CVE23_RS14195
uniprot id: A0A2K8QNC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1778540:CVE23 RS14975
gene id: 1778540:CVE23_RS14975
uniprot id: A0A2K8QNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS14135
gene id: 1778540:CVE23_RS14135
uniprot id: A0A2K8QNB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

1778540:CVE23 RS15180
gene id: 1778540:CVE23_RS15180
uniprot id: A0A2K8QNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS12010
gene id: 1778540:CVE23_RS12010
uniprot id: A0A2K8QNJ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1778540:CVE23 RS12870
gene id: 1778540:CVE23_RS12870
uniprot id: A0A2K8QMQ8
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS11425
gene id: 1778540:CVE23_RS11425
uniprot id: A0A2K8QNA0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1778540:CVE23 RS17655
gene id: 1778540:CVE23_RS17655
uniprot id: A0A2K8QQ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1778540:CVE23 RS08185
gene id: 1778540:CVE23_RS08185
uniprot id: A0A2K8QKC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS05735
gene id: 1778540:CVE23_RS05735
uniprot id: A0A2K8QJC8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

1778540:CVE23 RS11460
gene id: 1778540:CVE23_RS11460
uniprot id: A0A2K8QP84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1778540:CVE23 RS21005
gene id: 1778540:CVE23_RS21005
uniprot id: A0A2K8QT11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

1778540:CVE23 RS17880
gene id: 1778540:CVE23_RS17880
uniprot id: A0A2K8QSE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1778540:CVE23 RS04855
gene id: 1778540:CVE23_RS04855
uniprot id: A0A2K8QIR9
names: Similarity
messages: Belongs to the MipA/OmpV family.

1778540:CVE23 RS13460
gene id: 1778540:CVE23_RS13460
uniprot id: A0A2K8QN29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1778540:CVE23 RS07025
gene id: 1778540:CVE23_RS07025
uniprot id: A0A2K8QK14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS01185
gene id: 1778540:CVE23_RS01185
uniprot id: A0A2K8QIZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1778540:CVE23 RS13005
gene id: 1778540:CVE23_RS13005
uniprot id: A0A2K8QMR8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1778540:CVE23 RS06410
gene id: 1778540:CVE23_RS06410
uniprot id: A0A2K8QJG7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1778540:CVE23 RS22305
gene id: 1778540:CVE23_RS22305
uniprot id: A0A2K8QSK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1778540:CVE23 RS12505
gene id: 1778540:CVE23_RS12505
uniprot id: A0A2K8QNS8
names: Subunit
messages: Monomer.

1778540:CVE23 RS14140
gene id: 1778540:CVE23_RS14140
uniprot id: A0A2K8QPS1
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

1778540:CVE23 RS10275
gene id: 1778540:CVE23_RS10275
uniprot id: A0A2K8QLC9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

1778540:CVE23 RS15535
gene id: 1778540:CVE23_RS15535
uniprot id: A0A2K8QP19
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1778540:CVE23 RS05360
gene id: 1778540:CVE23_RS05360
uniprot id: A0A2K8QJ02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1778540:CVE23 RS19320
gene id: 1778540:CVE23_RS19320
uniprot id: A0A2K8QR10
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS20775
gene id: 1778540:CVE23_RS20775
uniprot id: A0A2K8QRS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

1778540:CVE23 RS10155
gene id: 1778540:CVE23_RS10155
uniprot id: A0A2K8QLC8
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS00695
gene id: 1778540:CVE23_RS00695
uniprot id: A0A2K8QGI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS19225
gene id: 1778540:CVE23_RS19225
uniprot id: A0A2K8QQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1778540:CVE23 RS16370
gene id: 1778540:CVE23_RS16370
uniprot id: A0A2K8QPI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

1778540:CVE23 RS07100
gene id: 1778540:CVE23_RS07100
uniprot id: A0A2K8QJT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1778540:CVE23 RS20635
gene id: 1778540:CVE23_RS20635
uniprot id: A0A2K8QSS5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1778540:CVE23 RS06105
gene id: 1778540:CVE23_RS06105
uniprot id: A0A2K8QJB2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1778540:CVE23 RS10565
gene id: 1778540:CVE23_RS10565
uniprot id: A0A2K8QLI6
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1778540:CVE23 RS00910
gene id: 1778540:CVE23_RS00910
uniprot id: A0A2K8QGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1778540:CVE23 RS19405
gene id: 1778540:CVE23_RS19405
uniprot id: A0A2K8QR06
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1778540:CVE23 RS03820
gene id: 1778540:CVE23_RS03820
uniprot id: A0A2K8QI48
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1778540:CVE23 RS21780
gene id: 1778540:CVE23_RS21780
uniprot id: A0A2K8QS92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1778540:CVE23 RS16385
gene id: 1778540:CVE23_RS16385
uniprot id: A0A2K8QRR5
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

1778540:CVE23 RS05740
gene id: 1778540:CVE23_RS05740
uniprot id: A0A2K8QJ41
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1778540:CVE23 RS07355
gene id: 1778540:CVE23_RS07355
uniprot id: A0A2K8QK76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS06875
gene id: 1778540:CVE23_RS06875
uniprot id: A0A2K8QL26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1778540:CVE23 RS21285
gene id: 1778540:CVE23_RS21285
uniprot id: A0A2K8QS17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

1778540:CVE23 RS06730
gene id: 1778540:CVE23_RS06730
uniprot id: A0A2K8QJL9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1778540:CVE23 RS03830
gene id: 1778540:CVE23_RS03830
uniprot id: A0A2K8QI84
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

1778540:CVE23 RS20200
gene id: 1778540:CVE23_RS20200
uniprot id: A0A2K8QSL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1778540:CVE23 RS17355
gene id: 1778540:CVE23_RS17355
uniprot id: A0A2K8QPX5
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1778540:CVE23 RS00875
gene id: 1778540:CVE23_RS00875
uniprot id: A0A2K8QGR8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1778540:CVE23 RS01715
gene id: 1778540:CVE23_RS01715
uniprot id: A0A2K8QH55
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

1778540:CVE23 RS18815
gene id: 1778540:CVE23_RS18815
uniprot id: A0A2K8QQP1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

1778540:CVE23 RS19645
gene id: 1778540:CVE23_RS19645
uniprot id: A0A2K8QR70
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

1778540:CVE23 RS17285
gene id: 1778540:CVE23_RS17285
uniprot id: A0A2K8QR58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1778540:CVE23 RS20240
gene id: 1778540:CVE23_RS20240
uniprot id: A0A2K8QRH2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1778540:CVE23 RS17870
gene id: 1778540:CVE23_RS17870
uniprot id: A0A2K8QRE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

1778540:CVE23 RS21270
gene id: 1778540:CVE23_RS21270
uniprot id: A0A2K8QT56
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1778540:CVE23 RS00690
gene id: 1778540:CVE23_RS00690
uniprot id: A0A2K8QGJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS04210
gene id: 1778540:CVE23_RS04210
uniprot id: A0A2K8QIF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS04440
gene id: 1778540:CVE23_RS04440
uniprot id: A0A2K8QIG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1778540:CVE23 RS01785
gene id: 1778540:CVE23_RS01785
uniprot id: A0A2K8QH70
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1778540:CVE23 RS02125
gene id: 1778540:CVE23_RS02125
uniprot id: A0A2K8QHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1778540:CVE23 RS08330
gene id: 1778540:CVE23_RS08330
uniprot id: A0A2K8QKN6
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

1778540:CVE23 RS18965
gene id: 1778540:CVE23_RS18965
uniprot id: A0A2K8QRY2
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

1778540:CVE23 RS11205
gene id: 1778540:CVE23_RS11205
uniprot id: A0A2K8QLW3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS08135
gene id: 1778540:CVE23_RS08135
uniprot id: A0A2K8QLN2
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS06160
gene id: 1778540:CVE23_RS06160
uniprot id: A0A2K8QLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1778540:CVE23 RS06110
gene id: 1778540:CVE23_RS06110
uniprot id: A0A2K8QLG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1778540:CVE23 RS09540
gene id: 1778540:CVE23_RS09540
uniprot id: A0A2K8QMA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1778540:CVE23 RS16875
gene id: 1778540:CVE23_RS16875
uniprot id: A0A2K8QQZ8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1778540:CVE23 RS21300
gene id: 1778540:CVE23_RS21300
uniprot id: A0A2K8QU43
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1778540:CVE23 RS01510
gene id: 1778540:CVE23_RS01510
uniprot id: A0A2K8QGX1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS22290
gene id: 1778540:CVE23_RS22290
uniprot id: A0A2K8QUM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1778540:CVE23 RS09595
gene id: 1778540:CVE23_RS09595
uniprot id: A0A2K8QMB2
names: Similarity
messages: Belongs to the peptidase C40 family.

1778540:CVE23 RS11470
gene id: 1778540:CVE23_RS11470
uniprot id: A0A2K8QMC9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1778540:CVE23 RS16890
gene id: 1778540:CVE23_RS16890
uniprot id: A0A2K8QPR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1778540:CVE23 RS11555
gene id: 1778540:CVE23_RS11555
uniprot id: A0A2K8QM11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1778540:CVE23 RS13995
gene id: 1778540:CVE23_RS13995
uniprot id: A0A2K8QND4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

1778540:CVE23 RS05245
gene id: 1778540:CVE23_RS05245
uniprot id: A0A2K8QIY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

1778540:CVE23 RS21555
gene id: 1778540:CVE23_RS21555
uniprot id: A0A2K8QS65
names: Similarity
messages: Belongs to the leucine-binding protein family.

1778540:CVE23 RS22280
gene id: 1778540:CVE23_RS22280
uniprot id: A0A2K8QTN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1778540:CVE23 RS19370
gene id: 1778540:CVE23_RS19370
uniprot id: A0A2K8QT35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS15980
gene id: 1778540:CVE23_RS15980
uniprot id: A0A2K8QPE7
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

1778540:CVE23 RS09625
gene id: 1778540:CVE23_RS09625
uniprot id: A0A2K8QN96
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

1778540:CVE23 RS16805
gene id: 1778540:CVE23_RS16805
uniprot id: A0A2K8QPP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1778540:CVE23 RS21565
gene id: 1778540:CVE23_RS21565
uniprot id: A0A2K8QS76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1778540:CVE23 RS13065
gene id: 1778540:CVE23_RS13065
uniprot id: A0A2K8QMV3
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS21570
gene id: 1778540:CVE23_RS21570
uniprot id: A0A2K8QUA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1778540:CVE23 RS21340
gene id: 1778540:CVE23_RS21340
uniprot id: A0A2K8QS30
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1778540:CVE23 RS03435
gene id: 1778540:CVE23_RS03435
uniprot id: A0A2K8QHX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1778540:CVE23 RS20490
gene id: 1778540:CVE23_RS20490
uniprot id: A0A2K8QRM5
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.

1778540:CVE23 RS09105
gene id: 1778540:CVE23_RS09105
uniprot id: A0A2K8QM16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1778540:CVE23 RS06710
gene id: 1778540:CVE23_RS06710
uniprot id: A0A2K8QKU5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1778540:CVE23 RS04915
gene id: 1778540:CVE23_RS04915
uniprot id: A0A2K8QIQ4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1778540:CVE23 RS01515
gene id: 1778540:CVE23_RS01515
uniprot id: A0A2K8QH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

1778540:CVE23 RS16140
gene id: 1778540:CVE23_RS16140
uniprot id: A0A2K8QPH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS04970
gene id: 1778540:CVE23_RS04970
uniprot id: A0A2K8QIQ5
names: Similarity
messages: Belongs to the peptidase C59 family.

1778540:CVE23 RS05780
gene id: 1778540:CVE23_RS05780
uniprot id: A0A2K8QKH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1778540:CVE23 RS04410
gene id: 1778540:CVE23_RS04410
uniprot id: A0A2K8QII3
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1778540:CVE23 RS14530
gene id: 1778540:CVE23_RS14530
uniprot id: A0A2K8QT95
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1778540:CVE23 RS01585
gene id: 1778540:CVE23_RS01585
uniprot id: A0A2K8QGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1778540:CVE23 RS04330
gene id: 1778540:CVE23_RS04330
uniprot id: A0A2K8QKM4
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS05420
gene id: 1778540:CVE23_RS05420
uniprot id: A0A2K8QJ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

1778540:CVE23 RS12155
gene id: 1778540:CVE23_RS12155
uniprot id: A0A2K8QT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

1778540:CVE23 RS06560
gene id: 1778540:CVE23_RS06560
uniprot id: A0A2K8QKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1778540:CVE23 RS00110
gene id: 1778540:CVE23_RS00110
uniprot id: A0A2K8QG79
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1778540:CVE23 RS05150
gene id: 1778540:CVE23_RS05150
uniprot id: A0A2K8QIU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

1778540:CVE23 RS18055
gene id: 1778540:CVE23_RS18055
uniprot id: A0A2K8QQN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1778540:CVE23 RS14130
gene id: 1778540:CVE23_RS14130
uniprot id: A0A2K8QNF2
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS08905
gene id: 1778540:CVE23_RS08905
uniprot id: A0A2K8QMW5
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1778540:CVE23 RS09915
gene id: 1778540:CVE23_RS09915
uniprot id: A0A2K8QL76
names: Similarity
messages: Belongs to the UPF0145 family.

1778540:CVE23 RS04630
gene id: 1778540:CVE23_RS04630
uniprot id: A0A2K8QKT5
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS19400
gene id: 1778540:CVE23_RS19400
uniprot id: A0A2K8QR69
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1778540:CVE23 RS17765
gene id: 1778540:CVE23_RS17765
uniprot id: A0A2K8QSB8
names: Subcellular Location Annotation
messages: Cell inner membrane

1778540:CVE23 RS16150
gene id: 1778540:CVE23_RS16150
uniprot id: A0A2K8QQQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS09090
gene id: 1778540:CVE23_RS09090
uniprot id: A0A2K8QL33
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS01350
gene id: 1778540:CVE23_RS01350
uniprot id: A0A2K8QGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS04030
gene id: 1778540:CVE23_RS04030
uniprot id: A0A2K8QI90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS19295
gene id: 1778540:CVE23_RS19295
uniprot id: A0A2K8QQY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1778540:CVE23 RS11870
gene id: 1778540:CVE23_RS11870
uniprot id: A0A2K8QM55
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS14700
gene id: 1778540:CVE23_RS14700
uniprot id: A0A2K8QNQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1778540:CVE23 RS18000
gene id: 1778540:CVE23_RS18000
uniprot id: A0A2K8QQA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

1778540:CVE23 RS20875
gene id: 1778540:CVE23_RS20875
uniprot id: A0A2K8QRU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS04530
gene id: 1778540:CVE23_RS04530
uniprot id: A0A2K8QSS6
names: Similarity
messages: Belongs to the thioredoxin family.

1778540:CVE23 RS17605
gene id: 1778540:CVE23_RS17605
uniprot id: A0A2K8QQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1778540:CVE23 RS18635
gene id: 1778540:CVE23_RS18635
uniprot id: A0A2K8QRS4
names: Similarity
messages: Belongs to the LOG family.

1778540:CVE23 RS13475
gene id: 1778540:CVE23_RS13475
uniprot id: A0A2K8QMZ5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1778540:CVE23 RS20085
gene id: 1778540:CVE23_RS20085
uniprot id: A0A2K8QRD7
names: Similarity
messages: Belongs to the Smg family.

1778540:CVE23 RS06735
gene id: 1778540:CVE23_RS06735
uniprot id: A0A2K8QLT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS01560
gene id: 1778540:CVE23_RS01560
uniprot id: A0A2K8QH57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

1778540:CVE23 RS06620
gene id: 1778540:CVE23_RS06620
uniprot id: A0A2K8QKT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS15440
gene id: 1778540:CVE23_RS15440
uniprot id: A0A2K8QQ84
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS14265
gene id: 1778540:CVE23_RS14265
uniprot id: A0A2K8QNS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1778540:CVE23 RS01910
gene id: 1778540:CVE23_RS01910
uniprot id: A0A2K8QIH2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1778540:CVE23 RS11140
gene id: 1778540:CVE23_RS11140
uniprot id: A0A2K8QLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

1778540:CVE23 RS18155
gene id: 1778540:CVE23_RS18155
uniprot id: A0A2K8QSJ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1778540:CVE23 RS20090
gene id: 1778540:CVE23_RS20090
uniprot id: A0A2K8QTG3
names: Similarity
messages: Belongs to the DprA/Smf family.

1778540:CVE23 RS03525
gene id: 1778540:CVE23_RS03525
uniprot id: A0A2K8QI00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1778540:CVE23 RS07820
gene id: 1778540:CVE23_RS07820
uniprot id: A0A2K8QLE0
names: Similarity
messages: Belongs to the CFA/CMAS family.

1778540:CVE23 RS05650
gene id: 1778540:CVE23_RS05650
uniprot id: A0A2K8QKB6
names: Similarity
messages: Belongs to the YjdM family.

1778540:CVE23 RS22420
gene id: 1778540:CVE23_RS22420
uniprot id: A0A2K8QTR2
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

1778540:CVE23 RS22065
gene id: 1778540:CVE23_RS22065
uniprot id: A0A2K8QSP6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS01840
gene id: 1778540:CVE23_RS01840
uniprot id: A0A2K8QIB4
names: Subunit
messages: Monomer.

1778540:CVE23 RS20855
gene id: 1778540:CVE23_RS20855
uniprot id: A0A2K8QRV0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1778540:CVE23 RS10160
gene id: 1778540:CVE23_RS10160
uniprot id: A0A2K8QLB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1778540:CVE23 RS15200
gene id: 1778540:CVE23_RS15200
uniprot id: A0A2K8QQ41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane
messages: Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers.

1778540:CVE23 RS01105
gene id: 1778540:CVE23_RS01105
uniprot id: A0A2K8QI40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1778540:CVE23 RS05830
gene id: 1778540:CVE23_RS05830
uniprot id: A0A2K8QJ58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1778540:CVE23 RS11750
gene id: 1778540:CVE23_RS11750
uniprot id: A0A2K8QM41
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1778540:CVE23 RS01170
gene id: 1778540:CVE23_RS01170
uniprot id: A0A2K8QGR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1778540:CVE23 RS14260
gene id: 1778540:CVE23_RS14260
uniprot id: A0A2K8QNG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1778540:CVE23 RS17740
gene id: 1778540:CVE23_RS17740
uniprot id: A0A2K8QRD2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1778540:CVE23 RS10675
gene id: 1778540:CVE23_RS10675
uniprot id: A0A2K8QLM2
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

1778540:CVE23 RS13690
gene id: 1778540:CVE23_RS13690
uniprot id: A0A2K8QN38
names: Similarity
messages: Belongs to the peptidase C40 family.

1778540:CVE23 RS13615
gene id: 1778540:CVE23_RS13615
uniprot id: A0A2K8QN57
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

1778540:CVE23 RS14425
gene id: 1778540:CVE23_RS14425
uniprot id: A0A2K8QPW9
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS11770
gene id: 1778540:CVE23_RS11770
uniprot id: A0A2K8QM63
names: Similarity
messages: Belongs to the UPF0260 family.

1778540:CVE23 RS05405
gene id: 1778540:CVE23_RS05405
uniprot id: A0A2K8QIX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1778540:CVE23 RS19265
gene id: 1778540:CVE23_RS19265
uniprot id: A0A2K8QQZ9
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1778540:CVE23 RS13880
gene id: 1778540:CVE23_RS13880
uniprot id: A0A2K8QNA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1778540:CVE23 RS17970
gene id: 1778540:CVE23_RS17970
uniprot id: A0A2K8QQ82
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1778540:CVE23 RS05460
gene id: 1778540:CVE23_RS05460
uniprot id: A0A2K8QL58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1778540:CVE23 RS10950
gene id: 1778540:CVE23_RS10950
uniprot id: A0A2K8QN13
names: Similarity
messages: Belongs to the UPF0263 family.

1778540:CVE23 RS00915
gene id: 1778540:CVE23_RS00915
uniprot id: A0A2K8QGM8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1778540:CVE23 RS14630
gene id: 1778540:CVE23_RS14630
uniprot id: A0A2K8QNY2
names: Similarity
messages: Belongs to the HypE family.

1778540:CVE23 RS15590
gene id: 1778540:CVE23_RS15590
uniprot id: A0A2K8QP57
names: Similarity
messages: Belongs to the GppA/Ppx family.

1778540:CVE23 RS05620
gene id: 1778540:CVE23_RS05620
uniprot id: A0A2K8QJ19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS04405
gene id: 1778540:CVE23_RS04405
uniprot id: A0A2K8QKN4
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1778540:CVE23 RS03495
gene id: 1778540:CVE23_RS03495
uniprot id: A0A2K8QI24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1778540:CVE23 RS05130
gene id: 1778540:CVE23_RS05130
uniprot id: A0A2K8QIT6
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS04085
gene id: 1778540:CVE23_RS04085
uniprot id: A0A2K8QJM9
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1778540:CVE23 RS20405
gene id: 1778540:CVE23_RS20405
uniprot id: A0A2K8QRK4
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1778540:CVE23 RS00905
gene id: 1778540:CVE23_RS00905
uniprot id: A0A2K8QHV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1778540:CVE23 RS15345
gene id: 1778540:CVE23_RS15345
uniprot id: A0A2K8QR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS11930
gene id: 1778540:CVE23_RS11930
uniprot id: A0A2K8QPG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS03560
gene id: 1778540:CVE23_RS03560
uniprot id: A0A2K8QI12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1778540:CVE23 RS13290
gene id: 1778540:CVE23_RS13290
uniprot id: A0A2K8QMZ9
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

1778540:CVE23 RS09800
gene id: 1778540:CVE23_RS09800
uniprot id: A0A2K8QL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS02370
gene id: 1778540:CVE23_RS02370
uniprot id: A0A2K8QHL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.
messages: Homotrimer.

1778540:CVE23 RS08980
gene id: 1778540:CVE23_RS08980
uniprot id: A0A2K8QL07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1778540:CVE23 RS19340
gene id: 1778540:CVE23_RS19340
uniprot id: A0A2K8QR22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

1778540:CVE23 RS13865
gene id: 1778540:CVE23_RS13865
uniprot id: A0A2K8QN93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1778540:CVE23 RS08065
gene id: 1778540:CVE23_RS08065
uniprot id: A0A2K8QKB9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1778540:CVE23 RS13190
gene id: 1778540:CVE23_RS13190
uniprot id: A0A2K8QMU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1778540:CVE23 RS15605
gene id: 1778540:CVE23_RS15605
uniprot id: A0A2K8QP25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1778540:CVE23 RS01545
gene id: 1778540:CVE23_RS01545
uniprot id: A0A2K8QGZ1
names: Similarity
messages: Belongs to the peptidase U62 family.

1778540:CVE23 RS19335
gene id: 1778540:CVE23_RS19335
uniprot id: A0A2K8QR08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1778540:CVE23 RS09855
gene id: 1778540:CVE23_RS09855
uniprot id: A0A2K8QL65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1778540:CVE23 RS18850
gene id: 1778540:CVE23_RS18850
uniprot id: A0A2K8QQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1778540:CVE23 RS02090
gene id: 1778540:CVE23_RS02090
uniprot id: A0A2K8QHG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1778540:CVE23 RS13125
gene id: 1778540:CVE23_RS13125
uniprot id: A0A2K8QMW3
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

1778540:CVE23 RS14890
gene id: 1778540:CVE23_RS14890
uniprot id: A0A2K8QT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS08470
gene id: 1778540:CVE23_RS08470
uniprot id: A0A2K8QKH7
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1778540:CVE23 RS11795
gene id: 1778540:CVE23_RS11795
uniprot id: A0A2K8QM70
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1778540:CVE23 RS21110
gene id: 1778540:CVE23_RS21110
uniprot id: A0A2K8QS58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS16765
gene id: 1778540:CVE23_RS16765
uniprot id: A0A2K8QQX5
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1778540:CVE23 RS21430
gene id: 1778540:CVE23_RS21430
uniprot id: A0A2K8QS39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1778540:CVE23 RS20650
gene id: 1778540:CVE23_RS20650
uniprot id: A0A2K8QTT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

1778540:CVE23 RS05835
gene id: 1778540:CVE23_RS05835
uniprot id: A0A2K8QJ57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1778540:CVE23 RS09295
gene id: 1778540:CVE23_RS09295
uniprot id: A0A2K8QN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS09185
gene id: 1778540:CVE23_RS09185
uniprot id: A0A2K8QKS9
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

1778540:CVE23 RS17325
gene id: 1778540:CVE23_RS17325
uniprot id: A0A2K8QPY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1778540:CVE23 RS03290
gene id: 1778540:CVE23_RS03290
uniprot id: A0A2K8QJ28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1778540:CVE23 RS20590
gene id: 1778540:CVE23_RS20590
uniprot id: A0A2K8QRQ5
names: Subcellular Location Annotation
messages: Cell inner membrane

1778540:CVE23 RS14450
gene id: 1778540:CVE23_RS14450
uniprot id: A0A2K8QNV3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1778540:CVE23 RS14190
gene id: 1778540:CVE23_RS14190
uniprot id: A0A2K8QPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1778540:CVE23 RS06540
gene id: 1778540:CVE23_RS06540
uniprot id: A0A2K8QJL5
names: Similarity
messages: Belongs to the UPF0250 family.

1778540:CVE23 RS21805
gene id: 1778540:CVE23_RS21805
uniprot id: A0A2K8QSG9
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS10335
gene id: 1778540:CVE23_RS10335
uniprot id: A0A2K8QU65
names: Similarity
messages: Belongs to the GST superfamily.

1778540:CVE23 RS14715
gene id: 1778540:CVE23_RS14715
uniprot id: A0A2K8QNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1778540:CVE23 RS22300
gene id: 1778540:CVE23_RS22300
uniprot id: A0A2K8QST2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1778540:CVE23 RS03335
gene id: 1778540:CVE23_RS03335
uniprot id: A0A2K8QHZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

1778540:CVE23 RS09320
gene id: 1778540:CVE23_RS09320
uniprot id: A0A2K8QM59
names: Subcellular Location Annotation
messages: Cell outer membrane

1778540:CVE23 RS05695
gene id: 1778540:CVE23_RS05695
uniprot id: A0A2K8QJ66
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS19220
gene id: 1778540:CVE23_RS19220
uniprot id: A0A2K8QR88
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1778540:CVE23 RS16525
gene id: 1778540:CVE23_RS16525
uniprot id: A0A2K8QPP9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1778540:CVE23 RS21305
gene id: 1778540:CVE23_RS21305
uniprot id: A0A2K8QS12
names: Similarity
messages: Belongs to the FBPase class 2 family.

1778540:CVE23 RS15505
gene id: 1778540:CVE23_RS15505
uniprot id: A0A2K8QTA6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS05300
gene id: 1778540:CVE23_RS05300
uniprot id: A0A2K8QIW1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1778540:CVE23 RS02555
gene id: 1778540:CVE23_RS02555
uniprot id: A0A2K8QIP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1778540:CVE23 RS17920
gene id: 1778540:CVE23_RS17920
uniprot id: A0A2K8QQ77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1778540:CVE23 RS06705
gene id: 1778540:CVE23_RS06705
uniprot id: A0A2K8QJN9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1778540:CVE23 RS01600
gene id: 1778540:CVE23_RS01600
uniprot id: A0A2K8QJ62
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

1778540:CVE23 RS19455
gene id: 1778540:CVE23_RS19455
uniprot id: A0A2K8QR19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1778540:CVE23 RS05415
gene id: 1778540:CVE23_RS05415
uniprot id: A0A2K8QJ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1778540:CVE23 RS00210
gene id: 1778540:CVE23_RS00210
uniprot id: A0A2K8QGA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS12455
gene id: 1778540:CVE23_RS12455
uniprot id: A0A2K8QNW6
names: Similarity
messages: Belongs to the GST superfamily.

1778540:CVE23 RS09035
gene id: 1778540:CVE23_RS09035
uniprot id: A0A2K8QKQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1778540:CVE23 RS14005
gene id: 1778540:CVE23_RS14005
uniprot id: A0A2K8QPP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1778540:CVE23 RS22070
gene id: 1778540:CVE23_RS22070
uniprot id: A0A2K8QSG0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1778540:CVE23 RS00805
gene id: 1778540:CVE23_RS00805
uniprot id: A0A2K8QHY8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1778540:CVE23 RS03800
gene id: 1778540:CVE23_RS03800
uniprot id: A0A2K8QI52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1778540:CVE23 RS21030
gene id: 1778540:CVE23_RS21030
uniprot id: A0A2K8QU02
names: Similarity
messages: Belongs to the thioredoxin family.

1778540:CVE23 RS09310
gene id: 1778540:CVE23_RS09310
uniprot id: A0A2K8QKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

1778540:CVE23 RS09585
gene id: 1778540:CVE23_RS09585
uniprot id: A0A2K8QL14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS00850
gene id: 1778540:CVE23_RS00850
uniprot id: A0A2K8QGM3
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS16830
gene id: 1778540:CVE23_RS16830
uniprot id: A0A2K8QQY7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1778540:CVE23 RS19395
gene id: 1778540:CVE23_RS19395
uniprot id: A0A2K8QS74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1778540:CVE23 RS08975
gene id: 1778540:CVE23_RS08975
uniprot id: A0A2K8QU46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1778540:CVE23 RS21235
gene id: 1778540:CVE23_RS21235
uniprot id: A0A2K8QS14
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1778540:CVE23 RS12290
gene id: 1778540:CVE23_RS12290
uniprot id: A0A2K8QNT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS20230
gene id: 1778540:CVE23_RS20230
uniprot id: A0A2K8QRH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1778540:CVE23 RS20920
gene id: 1778540:CVE23_RS20920
uniprot id: A0A2K8QS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS08500
gene id: 1778540:CVE23_RS08500
uniprot id: A0A2K8QKE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1778540:CVE23 RS22530
gene id: 1778540:CVE23_RS22530
uniprot id: A0A2K8QTT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1778540:CVE23 RS05765
gene id: 1778540:CVE23_RS05765
uniprot id: A0A2K8QKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1778540:CVE23 RS03620
gene id: 1778540:CVE23_RS03620
uniprot id: A0A2K8QI23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1778540:CVE23 RS14990
gene id: 1778540:CVE23_RS14990
uniprot id: A0A2K8QR41
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1778540:CVE23 RS16470
gene id: 1778540:CVE23_RS16470
uniprot id: A0A2K8QPK7
names: Similarity
messages: Belongs to the P(II) protein family.

1778540:CVE23 RS09525
gene id: 1778540:CVE23_RS09525
uniprot id: A0A2K8QLA8
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS19315
gene id: 1778540:CVE23_RS19315
uniprot id: A0A2K8QT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1778540:CVE23 RS10875
gene id: 1778540:CVE23_RS10875
uniprot id: A0A2K8QNY4
names: Similarity
messages: Belongs to the UPF0225 family.

1778540:CVE23 RS01635
gene id: 1778540:CVE23_RS01635
uniprot id: A0A2K8QGZ2
names: Similarity
messages: Belongs to the BolA/IbaG family.

1778540:CVE23 RS12025
gene id: 1778540:CVE23_RS12025
uniprot id: A0A2K8QNN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS06260
gene id: 1778540:CVE23_RS06260
uniprot id: A0A2K8QTZ9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1778540:CVE23 RS01575
gene id: 1778540:CVE23_RS01575
uniprot id: A0A2K8QI61
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1778540:CVE23 RS22270
gene id: 1778540:CVE23_RS22270
uniprot id: A0A2K8QSQ0
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS06415
gene id: 1778540:CVE23_RS06415
uniprot id: A0A2K8QJF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1778540:CVE23 RS07330
gene id: 1778540:CVE23_RS07330
uniprot id: A0A2K8QJV7
names: Similarity
messages: Belongs to the Dps family.

1778540:CVE23 RS18800
gene id: 1778540:CVE23_RS18800
uniprot id: A0A2K8QQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1778540:CVE23 RS10595
gene id: 1778540:CVE23_RS10595
uniprot id: A0A2K8QLI5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1778540:CVE23 RS21550
gene id: 1778540:CVE23_RS21550
uniprot id: A0A2K8QSC1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS09050
gene id: 1778540:CVE23_RS09050
uniprot id: A0A2K8QKS3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1778540:CVE23 RS12270
gene id: 1778540:CVE23_RS12270
uniprot id: A0A2K8QMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

1778540:CVE23 RS07030
gene id: 1778540:CVE23_RS07030
uniprot id: A0A2K8QJR1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1778540:CVE23 RS18775
gene id: 1778540:CVE23_RS18775
uniprot id: A0A2K8QQP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-Me-Phe pilin family.
messages: Membrane

1778540:CVE23 RS20680
gene id: 1778540:CVE23_RS20680
uniprot id: A0A2K8QRX4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1778540:CVE23 RS02580
gene id: 1778540:CVE23_RS02580
uniprot id: A0A2K8QJQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

1778540:CVE23 RS04690
gene id: 1778540:CVE23_RS04690
uniprot id: A0A2K8QIS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1778540:CVE23 RS20075
gene id: 1778540:CVE23_RS20075
uniprot id: A0A2K8QRD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1778540:CVE23 RS11060
gene id: 1778540:CVE23_RS11060
uniprot id: A0A2K8QV47
names: Similarity
messages: Belongs to the peptidase S49 family.

1778540:CVE23 RS12300
gene id: 1778540:CVE23_RS12300
uniprot id: A0A2K8QPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS04190
gene id: 1778540:CVE23_RS04190
uniprot id: A0A2K8QIB2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1778540:CVE23 RS16705
gene id: 1778540:CVE23_RS16705
uniprot id: A0A2K8QQW9
names: Similarity
messages: Belongs to the CdaR family.

1778540:CVE23 RS13505
gene id: 1778540:CVE23_RS13505
uniprot id: A0A2K8QN16
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1778540:CVE23 RS17545
gene id: 1778540:CVE23_RS17545
uniprot id: A0A2K8QRA4
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS19365
gene id: 1778540:CVE23_RS19365
uniprot id: A0A2K8QQZ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1778540:CVE23 RS19255
gene id: 1778540:CVE23_RS19255
uniprot id: A0A2K8QQX3
names: Similarity
messages: Belongs to the threonine synthase family.

1778540:CVE23 RS18895
gene id: 1778540:CVE23_RS18895
uniprot id: A0A2K8QRX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1778540:CVE23 RS07170
gene id: 1778540:CVE23_RS07170
uniprot id: A0A2K8QL77
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1778540:CVE23 RS10965
gene id: 1778540:CVE23_RS10965
uniprot id: A0A2K8QN53
names: Similarity
messages: Belongs to the YciI family.

1778540:CVE23 RS13890
gene id: 1778540:CVE23_RS13890
uniprot id: A0A2K8QNB3
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1778540:CVE23 RS00970
gene id: 1778540:CVE23_RS00970
uniprot id: A0A2K8QGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS14905
gene id: 1778540:CVE23_RS14905
uniprot id: A0A2K8QNR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS20220
gene id: 1778540:CVE23_RS20220
uniprot id: A0A2K8QRG5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1778540:CVE23 RS02520
gene id: 1778540:CVE23_RS02520
uniprot id: A0A2K8QHG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1778540:CVE23 RS03365
gene id: 1778540:CVE23_RS03365
uniprot id: A0A2K8QHX3
names: Similarity
messages: Belongs to the UxaA family.

1778540:CVE23 RS13225
gene id: 1778540:CVE23_RS13225
uniprot id: A0A2K8QT69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1778540:CVE23 RS10210
gene id: 1778540:CVE23_RS10210
uniprot id: A0A2K8QMN2
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS20095
gene id: 1778540:CVE23_RS20095
uniprot id: A0A2K8QRF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1778540:CVE23 RS04585
gene id: 1778540:CVE23_RS04585
uniprot id: A0A2K8QIM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1778540:CVE23 RS20310
gene id: 1778540:CVE23_RS20310
uniprot id: A0A2K8QRI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

1778540:CVE23 RS07210
gene id: 1778540:CVE23_RS07210
uniprot id: A0A2K8QJV8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1778540:CVE23 RS05860
gene id: 1778540:CVE23_RS05860
uniprot id: A0A2K8QJF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1778540:CVE23 RS06485
gene id: 1778540:CVE23_RS06485
uniprot id: A0A2K8QJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

1778540:CVE23 RS13585
gene id: 1778540:CVE23_RS13585
uniprot id: A0A2K8QPG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1778540:CVE23 RS04665
gene id: 1778540:CVE23_RS04665
uniprot id: A0A2K8QIJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1778540:CVE23 RS16550
gene id: 1778540:CVE23_RS16550
uniprot id: A0A2K8QPN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1778540:CVE23 RS04415
gene id: 1778540:CVE23_RS04415
uniprot id: A0A2K8QIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1778540:CVE23 RS13295
gene id: 1778540:CVE23_RS13295
uniprot id: A0A2K8QP63
names: Similarity
messages: Belongs to the CFA/CMAS family.

1778540:CVE23 RS05090
gene id: 1778540:CVE23_RS05090
uniprot id: A0A2K8QIT0
names: Similarity
messages: Belongs to the CcdB toxin family.

1778540:CVE23 RS01490
gene id: 1778540:CVE23_RS01490
uniprot id: A0A2K8QJ42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1778540:CVE23 RS01455
gene id: 1778540:CVE23_RS01455
uniprot id: A0A2K8QH09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1778540:CVE23 RS14240
gene id: 1778540:CVE23_RS14240
uniprot id: A0A2K8QPU1
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1778540:CVE23 RS04035
gene id: 1778540:CVE23_RS04035
uniprot id: A0A2K8QKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS16065
gene id: 1778540:CVE23_RS16065
uniprot id: A0A2K8QUD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS15040
gene id: 1778540:CVE23_RS15040
uniprot id: A0A2K8QNT1
names: Similarity
messages: Belongs to the MlaA family.

1778540:CVE23 RS10670
gene id: 1778540:CVE23_RS10670
uniprot id: A0A2K8QLY5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS18545
gene id: 1778540:CVE23_RS18545
uniprot id: A0A2K8QQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS19470
gene id: 1778540:CVE23_RS19470
uniprot id: A0A2K8QT54
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1778540:CVE23 RS14150
gene id: 1778540:CVE23_RS14150
uniprot id: A0A2K8QQM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1778540:CVE23 RS02740
gene id: 1778540:CVE23_RS02740
uniprot id: A0A2K8QHJ7
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS20520
gene id: 1778540:CVE23_RS20520
uniprot id: A0A2K8QRM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1778540:CVE23 RS16595
gene id: 1778540:CVE23_RS16595
uniprot id: A0A2K8QRV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1778540:CVE23 RS09560
gene id: 1778540:CVE23_RS09560
uniprot id: A0A2K8QL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS11505
gene id: 1778540:CVE23_RS11505
uniprot id: A0A2K8QT83
names: Similarity
messages: Belongs to the UPF0162 family.

1778540:CVE23 RS04705
gene id: 1778540:CVE23_RS04705
uniprot id: A0A2K8QJU6
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

1778540:CVE23 RS05805
gene id: 1778540:CVE23_RS05805
uniprot id: A0A2K8QJ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1778540:CVE23 RS01265
gene id: 1778540:CVE23_RS01265
uniprot id: A0A2K8QI13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1778540:CVE23 RS02445
gene id: 1778540:CVE23_RS02445
uniprot id: A0A2K8QIM1
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaBAD and rhaT operons.
messages: Binds DNA as a dimer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS15405
gene id: 1778540:CVE23_RS15405
uniprot id: A0A2K8QRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS01425
gene id: 1778540:CVE23_RS01425
uniprot id: A0A2K8QI88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1778540:CVE23 RS17310
gene id: 1778540:CVE23_RS17310
uniprot id: A0A2K8QS49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1778540:CVE23 RS20730
gene id: 1778540:CVE23_RS20730
uniprot id: A0A2K8QRR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Homotetramer.
messages: Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.

1778540:CVE23 RS06010
gene id: 1778540:CVE23_RS06010
uniprot id: A0A2K8QJB9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1778540:CVE23 RS17775
gene id: 1778540:CVE23_RS17775
uniprot id: A0A2K8QTD3
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
messages: Catalyzes the reduction of tatronate semialdehyde to D-glycerate.

1778540:CVE23 RS06985
gene id: 1778540:CVE23_RS06985
uniprot id: A0A2K8QL01
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1778540:CVE23 RS22260
gene id: 1778540:CVE23_RS22260
uniprot id: A0A2K8QTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1778540:CVE23 RS03995
gene id: 1778540:CVE23_RS03995
uniprot id: A0A2K8QIF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

1778540:CVE23 RS19915
gene id: 1778540:CVE23_RS19915
uniprot id: A0A2K8QRA5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1778540:CVE23 RS08825
gene id: 1778540:CVE23_RS08825
uniprot id: A0A2K8QM08
names: Similarity
messages: Belongs to the fabD family.

1778540:CVE23 RS10860
gene id: 1778540:CVE23_RS10860
uniprot id: A0A2K8QN35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1778540:CVE23 RS02065
gene id: 1778540:CVE23_RS02065
uniprot id: A0A2K8QH73
names: Similarity
messages: Belongs to the RutC family.

1778540:CVE23 RS13490
gene id: 1778540:CVE23_RS13490
uniprot id: A0A2K8QQ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

1778540:CVE23 RS19215
gene id: 1778540:CVE23_RS19215
uniprot id: A0A2K8QQZ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1778540:CVE23 RS01415
gene id: 1778540:CVE23_RS01415
uniprot id: A0A2K8QGW0
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

1778540:CVE23 RS16435
gene id: 1778540:CVE23_RS16435
uniprot id: A0A2K8QRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS18315
gene id: 1778540:CVE23_RS18315
uniprot id: A0A2K8QQU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1778540:CVE23 RS16650
gene id: 1778540:CVE23_RS16650
uniprot id: A0A2K8QQW7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1778540:CVE23 RS12065
gene id: 1778540:CVE23_RS12065
uniprot id: A0A2K8QMC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

1778540:CVE23 RS17805
gene id: 1778540:CVE23_RS17805
uniprot id: A0A2K8QQB4
names: Function
names: Similarity
messages: Belongs to the UxaA family.
messages: Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).

1778540:CVE23 RS09515
gene id: 1778540:CVE23_RS09515
uniprot id: A0A2K8QN76
names: Similarity
messages: Belongs to the UPF0352 family.

1778540:CVE23 RS00920
gene id: 1778540:CVE23_RS00920
uniprot id: A0A2K8QTU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

1778540:CVE23 RS14725
gene id: 1778540:CVE23_RS14725
uniprot id: A0A2K8QNP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1778540:CVE23 RS17625
gene id: 1778540:CVE23_RS17625
uniprot id: A0A2K8QQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1778540:CVE23 RS03960
gene id: 1778540:CVE23_RS03960
uniprot id: A0A2K8QI86
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1778540:CVE23 RS17005
gene id: 1778540:CVE23_RS17005
uniprot id: A0A2K8QPS8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1778540:CVE23 RS13265
gene id: 1778540:CVE23_RS13265
uniprot id: A0A2K8QT57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1778540:CVE23 RS10225
gene id: 1778540:CVE23_RS10225
uniprot id: A0A2K8QLB9
names: Similarity
messages: Belongs to the UPF0265 family.

1778540:CVE23 RS16265
gene id: 1778540:CVE23_RS16265
uniprot id: A0A2K8QQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1778540:CVE23 RS18915
gene id: 1778540:CVE23_RS18915
uniprot id: A0A2K8QQQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1778540:CVE23 RS00820
gene id: 1778540:CVE23_RS00820
uniprot id: A0A2K8QGQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1778540:CVE23 RS19360
gene id: 1778540:CVE23_RS19360
uniprot id: A0A2K8QS52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1778540:CVE23 RS00350
gene id: 1778540:CVE23_RS00350
uniprot id: A0A2K8QSM3
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1778540:CVE23 RS01075
gene id: 1778540:CVE23_RS01075
uniprot id: A0A2K8QGR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1778540:CVE23 RS22400
gene id: 1778540:CVE23_RS22400
uniprot id: A0A2K8QSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS08180
gene id: 1778540:CVE23_RS08180
uniprot id: A0A2K8QLK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS18005
gene id: 1778540:CVE23_RS18005
uniprot id: A0A2K8QQD5
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

1778540:CVE23 RS01835
gene id: 1778540:CVE23_RS01835
uniprot id: A0A2K8QH79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

1778540:CVE23 RS04660
gene id: 1778540:CVE23_RS04660
uniprot id: A0A2K8QIK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1778540:CVE23 RS16820
gene id: 1778540:CVE23_RS16820
uniprot id: A0A2K8QPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS17955
gene id: 1778540:CVE23_RS17955
uniprot id: A0A2K8QQB6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1778540:CVE23 RS05925
gene id: 1778540:CVE23_RS05925
uniprot id: A0A2K8QKG5
names: Similarity
messages: Belongs to the UPF0234 family.

1778540:CVE23 RS00930
gene id: 1778540:CVE23_RS00930
uniprot id: A0A2K8QI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1778540:CVE23 RS11030
gene id: 1778540:CVE23_RS11030
uniprot id: A0A2K8QP14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1778540:CVE23 RS00590
gene id: 1778540:CVE23_RS00590
uniprot id: A0A2K8QHU9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1778540:CVE23 RS01485
gene id: 1778540:CVE23_RS01485
uniprot id: A0A2K8QGY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1778540:CVE23 RS04420
gene id: 1778540:CVE23_RS04420
uniprot id: A0A2K8QIF2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1778540:CVE23 RS19330
gene id: 1778540:CVE23_RS19330
uniprot id: A0A2K8QRA0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1778540:CVE23 RS14300
gene id: 1778540:CVE23_RS14300
uniprot id: A0A2K8QNF1
names: Similarity
messages: Belongs to the MotB family.

1778540:CVE23 RS03420
gene id: 1778540:CVE23_RS03420
uniprot id: A0A2K8QK53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1778540:CVE23 RS22435
gene id: 1778540:CVE23_RS22435
uniprot id: A0A2K8QTR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

1778540:CVE23 RS19685
gene id: 1778540:CVE23_RS19685
uniprot id: A0A2K8QSA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

1778540:CVE23 RS17400
gene id: 1778540:CVE23_RS17400
uniprot id: A0A2K8QR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS05325
gene id: 1778540:CVE23_RS05325
uniprot id: A0A2K8QIZ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

1778540:CVE23 RS19510
gene id: 1778540:CVE23_RS19510
uniprot id: A0A2K8QR26
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1778540:CVE23 RS21575
gene id: 1778540:CVE23_RS21575
uniprot id: A0A2K8QS60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1778540:CVE23 RS19460
gene id: 1778540:CVE23_RS19460
uniprot id: A0A2K8QS68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1778540:CVE23 RS20740
gene id: 1778540:CVE23_RS20740
uniprot id: A0A2K8QRX9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1778540:CVE23 RS20885
gene id: 1778540:CVE23_RS20885
uniprot id: A0A2K8QSY8
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1778540:CVE23 RS19970
gene id: 1778540:CVE23_RS19970
uniprot id: A0A2K8QSF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1778540:CVE23 RS20255
gene id: 1778540:CVE23_RS20255
uniprot id: A0A2K8QRM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1778540:CVE23 RS05135
gene id: 1778540:CVE23_RS05135
uniprot id: A0A2K8QIW7
names: Function
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1778540:CVE23 RS04255
gene id: 1778540:CVE23_RS04255
uniprot id: A0A2K8QJQ6
names: Similarity
messages: Belongs to the 2Fe2S plant-type ferredoxin family.

1778540:CVE23 RS10570
gene id: 1778540:CVE23_RS10570
uniprot id: A0A2K8QLW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS01275
gene id: 1778540:CVE23_RS01275
uniprot id: A0A2K8QGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

1778540:CVE23 RS14590
gene id: 1778540:CVE23_RS14590
uniprot id: A0A2K8QNN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1778540:CVE23 RS13955
gene id: 1778540:CVE23_RS13955
uniprot id: A0A2K8QPN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS03390
gene id: 1778540:CVE23_RS03390
uniprot id: A0A2K8QI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1778540:CVE23 RS20750
gene id: 1778540:CVE23_RS20750
uniprot id: A0A2K8QSU5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1778540:CVE23 RS14720
gene id: 1778540:CVE23_RS14720
uniprot id: A0A2K8QQY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1778540:CVE23 RS13600
gene id: 1778540:CVE23_RS13600
uniprot id: A0A2K8QN44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1778540:CVE23 RS01155
gene id: 1778540:CVE23_RS01155
uniprot id: A0A2K8QGV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

1778540:CVE23 RS03265
gene id: 1778540:CVE23_RS03265
uniprot id: A0A2K8QK21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1778540:CVE23 RS19140
gene id: 1778540:CVE23_RS19140
uniprot id: A0A2K8QQT5
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1778540:CVE23 RS02195
gene id: 1778540:CVE23_RS02195
uniprot id: A0A2K8QHI2
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1778540:CVE23 RS06920
gene id: 1778540:CVE23_RS06920
uniprot id: A0A2K8QJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1778540:CVE23 RS20930
gene id: 1778540:CVE23_RS20930
uniprot id: A0A2K8QRV5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1778540:CVE23 RS22025
gene id: 1778540:CVE23_RS22025
uniprot id: A0A2K8QTJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1778540:CVE23 RS05205
gene id: 1778540:CVE23_RS05205
uniprot id: A0A2K8QT14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1778540:CVE23 RS19940
gene id: 1778540:CVE23_RS19940
uniprot id: A0A2K8QRD3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1778540:CVE23 RS11175
gene id: 1778540:CVE23_RS11175
uniprot id: A0A2K8QLU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

1778540:CVE23 RS00155
gene id: 1778540:CVE23_RS00155
uniprot id: A0A2K8QG96
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS19415
gene id: 1778540:CVE23_RS19415
uniprot id: A0A2K8QR03
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1778540:CVE23 RS00015
gene id: 1778540:CVE23_RS00015
uniprot id: A0A2K8QHJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1778540:CVE23 RS03810
gene id: 1778540:CVE23_RS03810
uniprot id: A0A2K8QSU7
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1778540:CVE23 RS04335
gene id: 1778540:CVE23_RS04335
uniprot id: A0A2K8QIH3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1778540:CVE23 RS06265
gene id: 1778540:CVE23_RS06265
uniprot id: A0A2K8QJE1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1778540:CVE23 RS18670
gene id: 1778540:CVE23_RS18670
uniprot id: A0A2K8QQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1778540:CVE23 RS04445
gene id: 1778540:CVE23_RS04445
uniprot id: A0A2K8QUW7
names: Subunit
messages: Homodimer.

1778540:CVE23 RS18695
gene id: 1778540:CVE23_RS18695
uniprot id: A0A2K8QQM3
names: Similarity
messages: Belongs to the UPF0231 family.

1778540:CVE23 RS15500
gene id: 1778540:CVE23_RS15500
uniprot id: A0A2K8QP05
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1778540:CVE23 RS14400
gene id: 1778540:CVE23_RS14400
uniprot id: A0A2K8QNJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1778540:CVE23 RS20940
gene id: 1778540:CVE23_RS20940
uniprot id: A0A2K8QS16
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1778540:CVE23 RS20705
gene id: 1778540:CVE23_RS20705
uniprot id: A0A2K8QRS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1778540:CVE23 RS18265
gene id: 1778540:CVE23_RS18265
uniprot id: A0A2K8QQT0
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS20630
gene id: 1778540:CVE23_RS20630
uniprot id: A0A2K8QRP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1778540:CVE23 RS05310
gene id: 1778540:CVE23_RS05310
uniprot id: A0A2K8QIZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS06050
gene id: 1778540:CVE23_RS06050
uniprot id: A0A2K8QJA2
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS22285
gene id: 1778540:CVE23_RS22285
uniprot id: A0A2K8QSK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1778540:CVE23 RS06930
gene id: 1778540:CVE23_RS06930
uniprot id: A0A2K8QJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1778540:CVE23 RS13535
gene id: 1778540:CVE23_RS13535
uniprot id: A0A2K8QN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1778540:CVE23 RS21240
gene id: 1778540:CVE23_RS21240
uniprot id: A0A2K8QU33
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1778540:CVE23 RS16630
gene id: 1778540:CVE23_RS16630
uniprot id: A0A2K8QPR3
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

1778540:CVE23 RS11965
gene id: 1778540:CVE23_RS11965
uniprot id: A0A2K8QM78
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS14305
gene id: 1778540:CVE23_RS14305
uniprot id: A0A2K8QQQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1778540:CVE23 RS19635
gene id: 1778540:CVE23_RS19635
uniprot id: A0A2K8QR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1778540:CVE23 RS14745
gene id: 1778540:CVE23_RS14745
uniprot id: A0A2K8QNQ8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1778540:CVE23 RS15310
gene id: 1778540:CVE23_RS15310
uniprot id: A0A2K8QQ60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS17350
gene id: 1778540:CVE23_RS17350
uniprot id: A0A2K8QR63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1778540:CVE23 RS16610
gene id: 1778540:CVE23_RS16610
uniprot id: A0A2K8QPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

1778540:CVE23 RS15525
gene id: 1778540:CVE23_RS15525
uniprot id: A0A2K8QP36
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1778540:CVE23 RS18810
gene id: 1778540:CVE23_RS18810
uniprot id: A0A2K8QRU9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1778540:CVE23 RS18860
gene id: 1778540:CVE23_RS18860
uniprot id: A0A2K8QRV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1778540:CVE23 RS00075
gene id: 1778540:CVE23_RS00075
uniprot id: A0A2K8QIE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family. RNase BN subfamily.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.

1778540:CVE23 RS12095
gene id: 1778540:CVE23_RS12095
uniprot id: A0A2K8QMC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1778540:CVE23 RS19135
gene id: 1778540:CVE23_RS19135
uniprot id: A0A2K8QS19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Cell inner membrane
messages: Involved in succinate export with YjjP. Both proteins are required for export.
messages: Membrane
messages: The transporter is composed of YjjB and YjjP.

1778540:CVE23 RS16305
gene id: 1778540:CVE23_RS16305
uniprot id: A0A2K8QPK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1778540:CVE23 RS22465
gene id: 1778540:CVE23_RS22465
uniprot id: A0A2K8QSQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

1778540:CVE23 RS05875
gene id: 1778540:CVE23_RS05875
uniprot id: A0A2K8QKF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1778540:CVE23 RS19160
gene id: 1778540:CVE23_RS19160
uniprot id: A0A2K8QR78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1778540:CVE23 RS13875
gene id: 1778540:CVE23_RS13875
uniprot id: A0A2K8QN83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1778540:CVE23 RS09175
gene id: 1778540:CVE23_RS09175
uniprot id: A0A2K8QKR2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1778540:CVE23 RS16635
gene id: 1778540:CVE23_RS16635
uniprot id: A0A2K8QPN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1778540:CVE23 RS14810
gene id: 1778540:CVE23_RS14810
uniprot id: A0A2K8QNS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1778540:CVE23 RS05375
gene id: 1778540:CVE23_RS05375
uniprot id: A0A2K8QJ06
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1778540:CVE23 RS21460
gene id: 1778540:CVE23_RS21460
uniprot id: A0A2K8QU87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS18345
gene id: 1778540:CVE23_RS18345
uniprot id: A0A2K8QRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1778540:CVE23 RS10240
gene id: 1778540:CVE23_RS10240
uniprot id: A0A2K8QNM0
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS19180
gene id: 1778540:CVE23_RS19180
uniprot id: A0A2K8QS22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1778540:CVE23 RS18060
gene id: 1778540:CVE23_RS18060
uniprot id: A0A2K8QQB1
names: Similarity
messages: Belongs to the YggT family.

1778540:CVE23 RS12925
gene id: 1778540:CVE23_RS12925
uniprot id: A0A2K8QMR7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1778540:CVE23 RS01005
gene id: 1778540:CVE23_RS01005
uniprot id: A0A2K8QGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1778540:CVE23 RS14765
gene id: 1778540:CVE23_RS14765
uniprot id: A0A2K8QQ31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS11935
gene id: 1778540:CVE23_RS11935
uniprot id: A0A2K8QM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS01720
gene id: 1778540:CVE23_RS01720
uniprot id: A0A2K8QH85
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1778540:CVE23 RS10555
gene id: 1778540:CVE23_RS10555
uniprot id: A0A2K8QLI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1778540:CVE23 RS16560
gene id: 1778540:CVE23_RS16560
uniprot id: A0A2K8QPK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1778540:CVE23 RS19650
gene id: 1778540:CVE23_RS19650
uniprot id: A0A2K8QRF3
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

1778540:CVE23 RS07120
gene id: 1778540:CVE23_RS07120
uniprot id: A0A2K8QJT6
names: Similarity
messages: Belongs to the UPF0053 family.

1778540:CVE23 RS14160
gene id: 1778540:CVE23_RS14160
uniprot id: A0A2K8QNQ3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1778540:CVE23 RS20495
gene id: 1778540:CVE23_RS20495
uniprot id: A0A2K8QRU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1778540:CVE23 RS00185
gene id: 1778540:CVE23_RS00185
uniprot id: A0A2K8QGG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1778540:CVE23 RS06885
gene id: 1778540:CVE23_RS06885
uniprot id: A0A2K8QLW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1778540:CVE23 RS03570
gene id: 1778540:CVE23_RS03570
uniprot id: A0A2K8QJD2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1778540:CVE23 RS03500
gene id: 1778540:CVE23_RS03500
uniprot id: A0A2K8QJ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

1778540:CVE23 RS09785
gene id: 1778540:CVE23_RS09785
uniprot id: A0A2K8QL45
names: Similarity
messages: Belongs to the GST superfamily.

1778540:CVE23 RS06990
gene id: 1778540:CVE23_RS06990
uniprot id: A0A2K8QJR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1778540:CVE23 RS04835
gene id: 1778540:CVE23_RS04835
uniprot id: A0A2K8QKW4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1778540:CVE23 RS19630
gene id: 1778540:CVE23_RS19630
uniprot id: A0A2K8QS95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS18245
gene id: 1778540:CVE23_RS18245
uniprot id: A0A2K8QRK3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1778540:CVE23 RS01375
gene id: 1778540:CVE23_RS01375
uniprot id: A0A2K8QJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS14650
gene id: 1778540:CVE23_RS14650
uniprot id: A0A2K8QNP4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1778540:CVE23 RS04765
gene id: 1778540:CVE23_RS04765
uniprot id: A0A2K8QIL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS09755
gene id: 1778540:CVE23_RS09755
uniprot id: A0A2K8QL50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1778540:CVE23 RS15450
gene id: 1778540:CVE23_RS15450
uniprot id: A0A2K8QNZ5
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS15205
gene id: 1778540:CVE23_RS15205
uniprot id: A0A2K8QP00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1778540:CVE23 RS19895
gene id: 1778540:CVE23_RS19895
uniprot id: A0A2K8QSG3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1778540:CVE23 RS17330
gene id: 1778540:CVE23_RS17330
uniprot id: A0A2K8QPY8
names: Similarity
messages: Belongs to the YkuD family.

1778540:CVE23 RS01305
gene id: 1778540:CVE23_RS01305
uniprot id: A0A2K8QGU3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1778540:CVE23 RS21505
gene id: 1778540:CVE23_RS21505
uniprot id: A0A2K8QS61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS06420
gene id: 1778540:CVE23_RS06420
uniprot id: A0A2K8QKT7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1778540:CVE23 RS01450
gene id: 1778540:CVE23_RS01450
uniprot id: A0A2K8QGW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1778540:CVE23 RS07165
gene id: 1778540:CVE23_RS07165
uniprot id: A0A2K8QJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1778540:CVE23 RS13610
gene id: 1778540:CVE23_RS13610
uniprot id: A0A2K8QN33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1778540:CVE23 RS03635
gene id: 1778540:CVE23_RS03635
uniprot id: A0A2K8QJE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1778540:CVE23 RS02005
gene id: 1778540:CVE23_RS02005
uniprot id: A0A2K8QH69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS05890
gene id: 1778540:CVE23_RS05890
uniprot id: A0A2K8QKJ6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1778540:CVE23 RS09960
gene id: 1778540:CVE23_RS09960
uniprot id: A0A2K8QL75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1778540:CVE23 RS18750
gene id: 1778540:CVE23_RS18750
uniprot id: A0A2K8QQN3
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS07640
gene id: 1778540:CVE23_RS07640
uniprot id: A0A2K8QK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1778540:CVE23 RS14225
gene id: 1778540:CVE23_RS14225
uniprot id: A0A2K8QPL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1778540:CVE23 RS19885
gene id: 1778540:CVE23_RS19885
uniprot id: A0A2K8QRB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1778540:CVE23 RS10375
gene id: 1778540:CVE23_RS10375
uniprot id: A0A2K8QLG4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

1778540:CVE23 RS00400
gene id: 1778540:CVE23_RS00400
uniprot id: A0A2K8QGI1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1778540:CVE23 RS03675
gene id: 1778540:CVE23_RS03675
uniprot id: A0A2K8QSR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

1778540:CVE23 RS13220
gene id: 1778540:CVE23_RS13220
uniprot id: A0A2K8QMW8
names: Similarity
messages: Belongs to the GST superfamily.

1778540:CVE23 RS06240
gene id: 1778540:CVE23_RS06240
uniprot id: A0A2K8QKM2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1778540:CVE23 RS21770
gene id: 1778540:CVE23_RS21770
uniprot id: A0A2K8QSB3
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS22195
gene id: 1778540:CVE23_RS22195
uniprot id: A0A2K8QSI4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1778540:CVE23 RS18820
gene id: 1778540:CVE23_RS18820
uniprot id: A0A2K8QSU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

1778540:CVE23 RS20225
gene id: 1778540:CVE23_RS20225
uniprot id: A0A2K8QTJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1778540:CVE23 RS06940
gene id: 1778540:CVE23_RS06940
uniprot id: A0A2K8QJT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1778540:CVE23 RS11130
gene id: 1778540:CVE23_RS11130
uniprot id: A0A2K8QLS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

1778540:CVE23 RS08800
gene id: 1778540:CVE23_RS08800
uniprot id: A0A2K8QKL9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

1778540:CVE23 RS08105
gene id: 1778540:CVE23_RS08105
uniprot id: A0A2K8QKJ9
names: Similarity
messages: Belongs to the peptidase A31 family.

1778540:CVE23 RS14595
gene id: 1778540:CVE23_RS14595
uniprot id: A0A2K8QNJ9
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1778540:CVE23 RS20155
gene id: 1778540:CVE23_RS20155
uniprot id: A0A2K8QRK2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1778540:CVE23 RS20600
gene id: 1778540:CVE23_RS20600
uniprot id: A0A2K8QRP6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1778540:CVE23 RS22450
gene id: 1778540:CVE23_RS22450
uniprot id: A0A2K8QSL0
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

1778540:CVE23 RS17980
gene id: 1778540:CVE23_RS17980
uniprot id: A0A2K8QQ96
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1778540:CVE23 RS16835
gene id: 1778540:CVE23_RS16835
uniprot id: A0A2K8QT96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1778540:CVE23 RS20250
gene id: 1778540:CVE23_RS20250
uniprot id: A0A2K8QSM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1778540:CVE23 RS17840
gene id: 1778540:CVE23_RS17840
uniprot id: A0A2K8QQ71
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1778540:CVE23 RS22010
gene id: 1778540:CVE23_RS22010
uniprot id: A0A2K8QSN6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS03970
gene id: 1778540:CVE23_RS03970
uniprot id: A0A2K8QJK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS20620
gene id: 1778540:CVE23_RS20620
uniprot id: A0A2K8QSV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1778540:CVE23 RS14285
gene id: 1778540:CVE23_RS14285
uniprot id: A0A2K8QNI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1778540:CVE23 RS21295
gene id: 1778540:CVE23_RS21295
uniprot id: A0A2K8QS25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1778540:CVE23 RS14840
gene id: 1778540:CVE23_RS14840
uniprot id: A0A2K8QP21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1778540:CVE23 RS13870
gene id: 1778540:CVE23_RS13870
uniprot id: A0A2K8QNK1
names: Similarity
messages: Belongs to the fabD family.

1778540:CVE23 RS17685
gene id: 1778540:CVE23_RS17685
uniprot id: A0A2K8QRB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS18765
gene id: 1778540:CVE23_RS18765
uniprot id: A0A2K8QR05
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1778540:CVE23 RS16985
gene id: 1778540:CVE23_RS16985
uniprot id: A0A2K8QPR5
names: Subcellular Location Annotation
messages: Cytoplasm

1778540:CVE23 RS16785
gene id: 1778540:CVE23_RS16785
uniprot id: A0A2K8QPP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1778540:CVE23 RS10660
gene id: 1778540:CVE23_RS10660
uniprot id: A0A2K8QNU5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1778540:CVE23 RS12085
gene id: 1778540:CVE23_RS12085
uniprot id: A0A2K8QM97
names: Subcellular Location Annotation
messages: Cell inner membrane

1778540:CVE23 RS12560
gene id: 1778540:CVE23_RS12560
uniprot id: A0A2K8QNT6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS01875
gene id: 1778540:CVE23_RS01875
uniprot id: A0A2K8QHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1778540:CVE23 RS00610
gene id: 1778540:CVE23_RS00610
uniprot id: A0A2K8QGL7
names: Similarity
messages: Belongs to the autoinducer synthase family.

1778540:CVE23 RS16980
gene id: 1778540:CVE23_RS16980
uniprot id: A0A2K8QTC2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1778540:CVE23 RS14145
gene id: 1778540:CVE23_RS14145
uniprot id: A0A2K8QNB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1778540:CVE23 RS19260
gene id: 1778540:CVE23_RS19260
uniprot id: A0A2K8QT25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1778540:CVE23 RS09810
gene id: 1778540:CVE23_RS09810
uniprot id: A0A2K8QL63
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1778540:CVE23 RS07055
gene id: 1778540:CVE23_RS07055
uniprot id: A0A2K8QJR2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1778540:CVE23 RS10705
gene id: 1778540:CVE23_RS10705
uniprot id: A0A2K8QLL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1778540:CVE23 RS01360
gene id: 1778540:CVE23_RS01360
uniprot id: A0A2K8QI78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS14860
gene id: 1778540:CVE23_RS14860
uniprot id: A0A2K8QNT4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS04140
gene id: 1778540:CVE23_RS04140
uniprot id: A0A2K8QJN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0257 family.
messages: Cell membrane

1778540:CVE23 RS16360
gene id: 1778540:CVE23_RS16360
uniprot id: A0A2K8QQS8
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

1778540:CVE23 RS11340
gene id: 1778540:CVE23_RS11340
uniprot id: A0A2K8QNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1778540:CVE23 RS07005
gene id: 1778540:CVE23_RS07005
uniprot id: A0A2K8QJR6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1778540:CVE23 RS00085
gene id: 1778540:CVE23_RS00085
uniprot id: A0A2K8QGE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1778540:CVE23 RS01650
gene id: 1778540:CVE23_RS01650
uniprot id: A0A2K8QJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1778540:CVE23 RS14790
gene id: 1778540:CVE23_RS14790
uniprot id: A0A2K8QP13
names: Similarity
messages: Belongs to the UPF0304 family.

1778540:CVE23 RS20335
gene id: 1778540:CVE23_RS20335
uniprot id: A0A2K8QRR2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1778540:CVE23 RS20580
gene id: 1778540:CVE23_RS20580
uniprot id: A0A2K8QRN1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1778540:CVE23 RS12260
gene id: 1778540:CVE23_RS12260
uniprot id: A0A2K8QMR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS14880
gene id: 1778540:CVE23_RS14880
uniprot id: A0A2K8QR17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1778540:CVE23 RS04060
gene id: 1778540:CVE23_RS04060
uniprot id: A0A2K8QI93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1778540:CVE23 RS05900
gene id: 1778540:CVE23_RS05900
uniprot id: A0A2K8QLD0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1778540:CVE23 RS01440
gene id: 1778540:CVE23_RS01440
uniprot id: A0A2K8QH03
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1778540:CVE23 RS22100
gene id: 1778540:CVE23_RS22100
uniprot id: A0A2K8QSH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1778540:CVE23 RS13575
gene id: 1778540:CVE23_RS13575
uniprot id: A0A2K8QN51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

1778540:CVE23 RS15520
gene id: 1778540:CVE23_RS15520
uniprot id: A0A2K8QRB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1778540:CVE23 RS14705
gene id: 1778540:CVE23_RS14705
uniprot id: A0A2K8QNL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

1778540:CVE23 RS06065
gene id: 1778540:CVE23_RS06065
uniprot id: A0A2K8QJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS16250
gene id: 1778540:CVE23_RS16250
uniprot id: A0A2K8QQR3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1778540:CVE23 RS19450
gene id: 1778540:CVE23_RS19450
uniprot id: A0A2K8QR82
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1778540:CVE23 RS03935
gene id: 1778540:CVE23_RS03935
uniprot id: A0A2K8QIA5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1778540:CVE23 RS04290
gene id: 1778540:CVE23_RS04290
uniprot id: A0A2K8QT03
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS01175
gene id: 1778540:CVE23_RS01175
uniprot id: A0A2K8QI50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1778540:CVE23 RS11120
gene id: 1778540:CVE23_RS11120
uniprot id: A0A2K8QLT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1778540:CVE23 RS09040
gene id: 1778540:CVE23_RS09040
uniprot id: A0A2K8QKT6
names: Similarity
messages: Belongs to the MoaD family.

1778540:CVE23 RS06870
gene id: 1778540:CVE23_RS06870
uniprot id: A0A2K8QJN5
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1778540:CVE23 RS20130
gene id: 1778540:CVE23_RS20130
uniprot id: A0A2K8QRE5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1778540:CVE23 RS00415
gene id: 1778540:CVE23_RS00415
uniprot id: A0A2K8QGH6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1778540:CVE23 RS00795
gene id: 1778540:CVE23_RS00795
uniprot id: A0A2K8QGL2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

1778540:CVE23 RS07795
gene id: 1778540:CVE23_RS07795
uniprot id: A0A2K8QSX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS19440
gene id: 1778540:CVE23_RS19440
uniprot id: A0A2K8QR36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1778540:CVE23 RS08640
gene id: 1778540:CVE23_RS08640
uniprot id: A0A2K8QKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1778540:CVE23 RS06185
gene id: 1778540:CVE23_RS06185
uniprot id: A0A2K8QJF2
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1778540:CVE23 RS21085
gene id: 1778540:CVE23_RS21085
uniprot id: A0A2K8QRY4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS19380
gene id: 1778540:CVE23_RS19380
uniprot id: A0A2K8QRA9
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS14795
gene id: 1778540:CVE23_RS14795
uniprot id: A0A2K8QNP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS01595
gene id: 1778540:CVE23_RS01595
uniprot id: A0A2K8QH02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1778540:CVE23 RS14665
gene id: 1778540:CVE23_RS14665
uniprot id: A0A2K8QNK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1778540:CVE23 RS03415
gene id: 1778540:CVE23_RS03415
uniprot id: A0A2K8QHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1778540:CVE23 RS18780
gene id: 1778540:CVE23_RS18780
uniprot id: A0A2K8QUF8
names: Similarity
messages: Belongs to the GSP E family.

1778540:CVE23 RS06505
gene id: 1778540:CVE23_RS06505
uniprot id: A0A2K8QKS1
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1778540:CVE23 RS13510
gene id: 1778540:CVE23_RS13510
uniprot id: A0A2K8QN39
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1778540:CVE23 RS09655
gene id: 1778540:CVE23_RS09655
uniprot id: A0A2K8QL28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS06190
gene id: 1778540:CVE23_RS06190
uniprot id: A0A2K8QKL2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1778540:CVE23 RS20500
gene id: 1778540:CVE23_RS20500
uniprot id: A0A2K8QRM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1778540:CVE23 RS10560
gene id: 1778540:CVE23_RS10560
uniprot id: A0A2K8QNS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1778540:CVE23 RS08960
gene id: 1778540:CVE23_RS08960
uniprot id: A0A2K8QMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1778540:CVE23 RS21350
gene id: 1778540:CVE23_RS21350
uniprot id: A0A2K8QS40
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

1778540:CVE23 RS10065
gene id: 1778540:CVE23_RS10065
uniprot id: A0A2K8QL93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1778540:CVE23 RS21635
gene id: 1778540:CVE23_RS21635
uniprot id: A0A2K8QS71
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1778540:CVE23 RS00070
gene id: 1778540:CVE23_RS00070
uniprot id: A0A2K8QG78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1778540:CVE23 RS05840
gene id: 1778540:CVE23_RS05840
uniprot id: A0A2K8QKI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1778540:CVE23 RS20115
gene id: 1778540:CVE23_RS20115
uniprot id: A0A2K8QSH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1778540:CVE23 RS22295
gene id: 1778540:CVE23_RS22295
uniprot id: A0A2K8QSH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1778540:CVE23 RS20780
gene id: 1778540:CVE23_RS20780
uniprot id: A0A2K8QRS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

1778540:CVE23 RS21365
gene id: 1778540:CVE23_RS21365
uniprot id: A0A2K8QSB0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1778540:CVE23 RS17520
gene id: 1778540:CVE23_RS17520
uniprot id: A0A2K8QQ47
names: Similarity
messages: Belongs to the thioredoxin family.

1778540:CVE23 RS03775
gene id: 1778540:CVE23_RS03775
uniprot id: A0A2K8QI75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1778540:CVE23 RS08830
gene id: 1778540:CVE23_RS08830
uniprot id: A0A2K8QKM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1778540:CVE23 RS16700
gene id: 1778540:CVE23_RS16700
uniprot id: A0A2K8QPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1778540:CVE23 RS18945
gene id: 1778540:CVE23_RS18945
uniprot id: A0A2K8QRY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1778540:CVE23 RS16690
gene id: 1778540:CVE23_RS16690
uniprot id: A0A2K8QQ34
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1778540:CVE23 RS18875
gene id: 1778540:CVE23_RS18875
uniprot id: A0A2K8QQQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1778540:CVE23 RS00020
gene id: 1778540:CVE23_RS00020
uniprot id: A0A2K8QG66
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1778540:CVE23 RS01505
gene id: 1778540:CVE23_RS01505
uniprot id: A0A2K8QH46
names: Similarity
messages: Belongs to the peptidase U62 family.

1778540:CVE23 RS00055
gene id: 1778540:CVE23_RS00055
uniprot id: A0A2K8QG76
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1778540:CVE23 RS10255
gene id: 1778540:CVE23_RS10255
uniprot id: A0A2K8QLE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1778540:CVE23 RS20475
gene id: 1778540:CVE23_RS20475
uniprot id: A0A2K8QSP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1778540:CVE23 RS05315
gene id: 1778540:CVE23_RS05315
uniprot id: A0A2K8QJ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1778540:CVE23 RS20825
gene id: 1778540:CVE23_RS20825
uniprot id: A0A2K8QRT4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1778540:CVE23 RS15930
gene id: 1778540:CVE23_RS15930
uniprot id: A0A2K8QPE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

1778540:CVE23 RS09200
gene id: 1778540:CVE23_RS09200
uniprot id: A0A2K8QL48
names: Similarity
messages: Belongs to the peptidase S11 family.

1778540:CVE23 RS13770
gene id: 1778540:CVE23_RS13770
uniprot id: A0A2K8QN64
names: Subcellular Location Annotation
messages: Membrane

1778540:CVE23 RS03240
gene id: 1778540:CVE23_RS03240
uniprot id: A0A2K8QJ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1778540:CVE23 RS13735
gene id: 1778540:CVE23_RS13735
uniprot id: A0A2K8QN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1778540:CVE23 RS06275
gene id: 1778540:CVE23_RS06275
uniprot id: A0A2K8QJG6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

1778540:CVE23 RS08590
gene id: 1778540:CVE23_RS08590
uniprot id: A0A2K8QKK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1778540:CVE23 RS16880
gene id: 1778540:CVE23_RS16880
uniprot id: A0A2K8QTC3
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1778540:CVE23 RS00215
gene id: 1778540:CVE23_RS00215
uniprot id: A0A2K8QGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1778540:CVE23 RS01880
gene id: 1778540:CVE23_RS01880
uniprot id: A0A2K8QH39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1778540:CVE23 RS19430
gene id: 1778540:CVE23_RS19430
uniprot id: A0A2K8QRC4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1778540:CVE23 RS02595
gene id: 1778540:CVE23_RS02595
uniprot id: A0A2K8QHP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

1778540:CVE23 RS16020
gene id: 1778540:CVE23_RS16020
uniprot id: A0A2K8QPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1778540:CVE23 RS10030
gene id: 1778540:CVE23_RS10030
uniprot id: A0A2K8QT10
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.