1769779:AUP74 RS06105
gene id: 1769779:AUP74_RS06105
uniprot id: A0A1C9W6C2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS16065
gene id: 1769779:AUP74_RS16065
uniprot id: A0A1C9WBU2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1769779:AUP74 RS06335
gene id: 1769779:AUP74_RS06335
uniprot id: A0A1C9W6F3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1769779:AUP74 RS02240
gene id: 1769779:AUP74_RS02240
uniprot id: A0A1C9W451
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1769779:AUP74 RS13165
gene id: 1769779:AUP74_RS13165
uniprot id: A0A1C9WA68
names: Similarity
messages: Belongs to the DsrF/TusC family.

1769779:AUP74 RS03920
gene id: 1769779:AUP74_RS03920
uniprot id: A0A1C9W535
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS00955
gene id: 1769779:AUP74_RS00955
uniprot id: A0A1C9W3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1769779:AUP74 RS00980
gene id: 1769779:AUP74_RS00980
uniprot id: A0A1C9W3D9
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS08205
gene id: 1769779:AUP74_RS08205
uniprot id: A0A1C9W7H3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1769779:AUP74 RS03145
gene id: 1769779:AUP74_RS03145
uniprot id: A0A1C9W4M2
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS02915
gene id: 1769779:AUP74_RS02915
uniprot id: A0A1C9W4H7
names: Similarity
messages: Belongs to the peptidase S8 family.

1769779:AUP74 RS15555
gene id: 1769779:AUP74_RS15555
uniprot id: A0A1C9WBH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1769779:AUP74 RS09415
gene id: 1769779:AUP74_RS09415
uniprot id: A0A1C9W869
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1769779:AUP74 RS12775
gene id: 1769779:AUP74_RS12775
uniprot id: A0A1C9W9Y8
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1769779:AUP74 RS02270
gene id: 1769779:AUP74_RS02270
uniprot id: A0A1C9W446
names: Similarity
messages: Belongs to the PhzF family.

1769779:AUP74 RS07705
gene id: 1769779:AUP74_RS07705
uniprot id: A0A1C9W779
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1769779:AUP74 RS11480
gene id: 1769779:AUP74_RS11480
uniprot id: A0A1C9W980
names: Similarity
messages: Belongs to the MipA/OmpV family.

1769779:AUP74 RS12475
gene id: 1769779:AUP74_RS12475
uniprot id: A0A1C9W9T9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1769779:AUP74 RS17465
gene id: 1769779:AUP74_RS17465
uniprot id: A0A1C9W479
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1769779:AUP74 RS08260
gene id: 1769779:AUP74_RS08260
uniprot id: A0A1C9W7J1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1769779:AUP74 RS00745
gene id: 1769779:AUP74_RS00745
uniprot id: A0A1C9W3B3
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS15460
gene id: 1769779:AUP74_RS15460
uniprot id: A0A1C9WBE9
names: Similarity
messages: Belongs to the UPF0234 family.

1769779:AUP74 RS09350
gene id: 1769779:AUP74_RS09350
uniprot id: A0A1C9W840
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1769779:AUP74 RS12160
gene id: 1769779:AUP74_RS12160
uniprot id: A0A1C9W9K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1769779:AUP74 RS11995
gene id: 1769779:AUP74_RS11995
uniprot id: A0A1C9W9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1769779:AUP74 RS00580
gene id: 1769779:AUP74_RS00580
uniprot id: A0A1C9W373
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1769779:AUP74 RS08430
gene id: 1769779:AUP74_RS08430
uniprot id: A0A1C9W7K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1769779:AUP74 RS02160
gene id: 1769779:AUP74_RS02160
uniprot id: A0A1C9W422
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1769779:AUP74 RS01965
gene id: 1769779:AUP74_RS01965
uniprot id: A0A1C9W3Z1
names: Similarity
messages: Belongs to the YkuD family.

1769779:AUP74 RS08710
gene id: 1769779:AUP74_RS08710
uniprot id: A0A1C9W7R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1769779:AUP74 RS01495
gene id: 1769779:AUP74_RS01495
uniprot id: A0A1C9W3P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1769779:AUP74 RS01815
gene id: 1769779:AUP74_RS01815
uniprot id: A0A1C9W3V3
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS09055
gene id: 1769779:AUP74_RS09055
uniprot id: A0A1C9W7Y7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1769779:AUP74 RS14170
gene id: 1769779:AUP74_RS14170
uniprot id: A0A1C9WAS3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1769779:AUP74 RS11575
gene id: 1769779:AUP74_RS11575
uniprot id: A0A1C9W9B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1769779:AUP74 RS00200
gene id: 1769779:AUP74_RS00200
uniprot id: A0A1C9W302
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1769779:AUP74 RS14780
gene id: 1769779:AUP74_RS14780
uniprot id: A0A1C9WB22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1769779:AUP74 RS00865
gene id: 1769779:AUP74_RS00865
uniprot id: A0A1C9W3D5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1769779:AUP74 RS13435
gene id: 1769779:AUP74_RS13435
uniprot id: A0A1C9WAH7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1769779:AUP74 RS05030
gene id: 1769779:AUP74_RS05030
uniprot id: A0A1C9W5Q9
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

1769779:AUP74 RS13120
gene id: 1769779:AUP74_RS13120
uniprot id: A0A1C9WA46
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1769779:AUP74 RS16930
gene id: 1769779:AUP74_RS16930
uniprot id: A0A1C9WC82
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1769779:AUP74 RS05950
gene id: 1769779:AUP74_RS05950
uniprot id: A0A1C9W693
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1769779:AUP74 RS06870
gene id: 1769779:AUP74_RS06870
uniprot id: A0A1C9W6P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1769779:AUP74 RS07985
gene id: 1769779:AUP74_RS07985
uniprot id: A0A1C9W7F0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS04365
gene id: 1769779:AUP74_RS04365
uniprot id: A0A1C9W5F1
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS01405
gene id: 1769779:AUP74_RS01405
uniprot id: A0A1C9W3M6
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1769779:AUP74 RS09005
gene id: 1769779:AUP74_RS09005
uniprot id: A0A1C9W7W8
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1769779:AUP74 RS12445
gene id: 1769779:AUP74_RS12445
uniprot id: A0A1C9W9U9
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS08460
gene id: 1769779:AUP74_RS08460
uniprot id: A0A1C9W7L5
names: Similarity
messages: Belongs to the UPF0250 family.

1769779:AUP74 RS06850
gene id: 1769779:AUP74_RS06850
uniprot id: A0A1C9W6R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1769779:AUP74 RS09955
gene id: 1769779:AUP74_RS09955
uniprot id: A0A1C9W8F8
names: Similarity
messages: Belongs to the thioredoxin family.

1769779:AUP74 RS10510
gene id: 1769779:AUP74_RS10510
uniprot id: A0A1C9W8R1
names: Similarity
messages: Belongs to the UPF0270 family.

1769779:AUP74 RS12895
gene id: 1769779:AUP74_RS12895
uniprot id: A0A1C9WA42
names: Cofactor
messages: Can also use Mn(2+) ion.

1769779:AUP74 RS08610
gene id: 1769779:AUP74_RS08610
uniprot id: A0A1C9W7N8
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS13255
gene id: 1769779:AUP74_RS13255
uniprot id: A0A1C9WAA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1769779:AUP74 RS00365
gene id: 1769779:AUP74_RS00365
uniprot id: A0A1C9W322
names: Similarity
messages: Belongs to the PhoH family.

1769779:AUP74 RS11295
gene id: 1769779:AUP74_RS11295
uniprot id: A0A1C9W948
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1769779:AUP74 RS11140
gene id: 1769779:AUP74_RS11140
uniprot id: A0A1C9W922
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1769779:AUP74 RS12235
gene id: 1769779:AUP74_RS12235
uniprot id: A0A1C9W9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1769779:AUP74 RS12595
gene id: 1769779:AUP74_RS12595
uniprot id: A0A1C9W9Y1
names: Similarity
messages: Belongs to the HypD family.

1769779:AUP74 RS10430
gene id: 1769779:AUP74_RS10430
uniprot id: A0A1C9W8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1769779:AUP74 RS13995
gene id: 1769779:AUP74_RS13995
uniprot id: A0A1C9WAN2
names: Similarity
messages: Belongs to the peptidase C40 family.

1769779:AUP74 RS15730
gene id: 1769779:AUP74_RS15730
uniprot id: A0A1C9WBK6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1769779:AUP74 RS12825
gene id: 1769779:AUP74_RS12825
uniprot id: A0A1C9WA00
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1769779:AUP74 RS06385
gene id: 1769779:AUP74_RS06385
uniprot id: A0A1C9W6G0
names: Similarity
messages: Belongs to the UPF0229 family.

1769779:AUP74 RS11665
gene id: 1769779:AUP74_RS11665
uniprot id: A0A1C9W9C2
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1769779:AUP74 RS14340
gene id: 1769779:AUP74_RS14340
uniprot id: A0A1C9WAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS14830
gene id: 1769779:AUP74_RS14830
uniprot id: A0A1C9WB25
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1769779:AUP74 RS04620
gene id: 1769779:AUP74_RS04620
uniprot id: A0A1C9W5I0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1769779:AUP74 RS03970
gene id: 1769779:AUP74_RS03970
uniprot id: A0A1C9W548
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS08945
gene id: 1769779:AUP74_RS08945
uniprot id: A0A1C9W7U3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1769779:AUP74 RS01120
gene id: 1769779:AUP74_RS01120
uniprot id: A0A1C9W3H6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS05485
gene id: 1769779:AUP74_RS05485
uniprot id: A0A1C9W5Z1
names: Similarity
messages: Belongs to the GSP E family.

1769779:AUP74 RS05935
gene id: 1769779:AUP74_RS05935
uniprot id: A0A1C9W695
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1769779:AUP74 RS03940
gene id: 1769779:AUP74_RS03940
uniprot id: A0A1C9W520
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1769779:AUP74 RS04300
gene id: 1769779:AUP74_RS04300
uniprot id: A0A1C9W5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1769779:AUP74 RS13160
gene id: 1769779:AUP74_RS13160
uniprot id: A0A1C9WA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1769779:AUP74 RS03985
gene id: 1769779:AUP74_RS03985
uniprot id: A0A1C9W549
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1769779:AUP74 RS00835
gene id: 1769779:AUP74_RS00835
uniprot id: A0A1C9W3C3
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1769779:AUP74 RS05085
gene id: 1769779:AUP74_RS05085
uniprot id: A0A1C9W5R3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1769779:AUP74 RS12880
gene id: 1769779:AUP74_RS12880
uniprot id: A0A1C9WA29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1769779:AUP74 RS06000
gene id: 1769779:AUP74_RS06000
uniprot id: A0A1C9W6A4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1769779:AUP74 RS03075
gene id: 1769779:AUP74_RS03075
uniprot id: A0A1C9W4L7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1769779:AUP74 RS00205
gene id: 1769779:AUP74_RS00205
uniprot id: A0A1C9W2Z6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1769779:AUP74 RS14640
gene id: 1769779:AUP74_RS14640
uniprot id: A0A1C9WB14
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1769779:AUP74 RS07540
gene id: 1769779:AUP74_RS07540
uniprot id: A0A1C9W745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1769779:AUP74 RS09110
gene id: 1769779:AUP74_RS09110
uniprot id: A0A1C9W7Z4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1769779:AUP74 RS04215
gene id: 1769779:AUP74_RS04215
uniprot id: A0A1C9W586
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1769779:AUP74 RS11340
gene id: 1769779:AUP74_RS11340
uniprot id: A0A1C9W956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS04100
gene id: 1769779:AUP74_RS04100
uniprot id: A0A1C9W561
names: Similarity
messages: Belongs to the RutC family.

1769779:AUP74 RS13465
gene id: 1769779:AUP74_RS13465
uniprot id: A0A1C9WAB8
names: Similarity
messages: Belongs to the SlyX family.

1769779:AUP74 RS15835
gene id: 1769779:AUP74_RS15835
uniprot id: A0A1C9WBM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS09880
gene id: 1769779:AUP74_RS09880
uniprot id: A0A1C9W8E0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1769779:AUP74 RS16045
gene id: 1769779:AUP74_RS16045
uniprot id: A0A1C9WBV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1769779:AUP74 RS09290
gene id: 1769779:AUP74_RS09290
uniprot id: A0A1C9W817
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1769779:AUP74 RS16905
gene id: 1769779:AUP74_RS16905
uniprot id: A0A1C9WC83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1769779:AUP74 RS08185
gene id: 1769779:AUP74_RS08185
uniprot id: A0A1C9W7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1769779:AUP74 RS15550
gene id: 1769779:AUP74_RS15550
uniprot id: A0A1C9WBG9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1769779:AUP74 RS05455
gene id: 1769779:AUP74_RS05455
uniprot id: A0A1C9W5Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1769779:AUP74 RS12405
gene id: 1769779:AUP74_RS12405
uniprot id: A0A1C9W9Q7
names: Similarity
messages: Belongs to the peptidase S41A family.

1769779:AUP74 RS10275
gene id: 1769779:AUP74_RS10275
uniprot id: A0A1C9W8L5
names: Similarity
messages: Belongs to the aspartokinase family.

1769779:AUP74 RS15205
gene id: 1769779:AUP74_RS15205
uniprot id: A0A1C9WBA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS16220
gene id: 1769779:AUP74_RS16220
uniprot id: A0A1C9WBU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1769779:AUP74 RS12790
gene id: 1769779:AUP74_RS12790
uniprot id: A0A1C9W9Y5
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1769779:AUP74 RS12290
gene id: 1769779:AUP74_RS12290
uniprot id: A0A1C9W9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS02590
gene id: 1769779:AUP74_RS02590
uniprot id: A0A1C9W4C8
names: Subcellular Location Annotation
messages: Cytoplasm

1769779:AUP74 RS09170
gene id: 1769779:AUP74_RS09170
uniprot id: A0A1C9W7Z0
names: Similarity
messages: Belongs to the YfgM family.

1769779:AUP74 RS08920
gene id: 1769779:AUP74_RS08920
uniprot id: A0A1C9W7X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1769779:AUP74 RS04000
gene id: 1769779:AUP74_RS04000
uniprot id: A0A1C9W537
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS03995
gene id: 1769779:AUP74_RS03995
uniprot id: A0A1C9W571
names: Similarity
messages: Belongs to the UPF0758 family.

1769779:AUP74 RS04240
gene id: 1769779:AUP74_RS04240
uniprot id: A0A1C9W594
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1769779:AUP74 RS04560
gene id: 1769779:AUP74_RS04560
uniprot id: A0A1C9W5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1769779:AUP74 RS09805
gene id: 1769779:AUP74_RS09805
uniprot id: A0A1C9W8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1769779:AUP74 RS12215
gene id: 1769779:AUP74_RS12215
uniprot id: A0A1C9W9M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1769779:AUP74 RS15260
gene id: 1769779:AUP74_RS15260
uniprot id: A0A1C9WBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS14895
gene id: 1769779:AUP74_RS14895
uniprot id: A0A1C9WB36
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1769779:AUP74 RS12650
gene id: 1769779:AUP74_RS12650
uniprot id: A0A1C9W9V6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1769779:AUP74 RS05650
gene id: 1769779:AUP74_RS05650
uniprot id: A0A1C9W620
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1769779:AUP74 RS03000
gene id: 1769779:AUP74_RS03000
uniprot id: A0A1C9W4J4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1769779:AUP74 RS00965
gene id: 1769779:AUP74_RS00965
uniprot id: A0A1C9W3E7
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1769779:AUP74 RS07095
gene id: 1769779:AUP74_RS07095
uniprot id: A0A1C9W6V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1769779:AUP74 RS06090
gene id: 1769779:AUP74_RS06090
uniprot id: A0A1C9W6B1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1769779:AUP74 RS14790
gene id: 1769779:AUP74_RS14790
uniprot id: A0A1C9WB35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1769779:AUP74 RS07905
gene id: 1769779:AUP74_RS07905
uniprot id: A0A1C9W7B3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS07015
gene id: 1769779:AUP74_RS07015
uniprot id: A0A1C9W6S9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1769779:AUP74 RS15705
gene id: 1769779:AUP74_RS15705
uniprot id: A0A1C9WBK4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1769779:AUP74 RS10695
gene id: 1769779:AUP74_RS10695
uniprot id: A0A1C9W8Y8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS08720
gene id: 1769779:AUP74_RS08720
uniprot id: A0A1C9W7R7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1769779:AUP74 RS03755
gene id: 1769779:AUP74_RS03755
uniprot id: A0A1C9W501
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1769779:AUP74 RS12015
gene id: 1769779:AUP74_RS12015
uniprot id: A0A1C9W9P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1769779:AUP74 RS15140
gene id: 1769779:AUP74_RS15140
uniprot id: A0A1C9WBA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1769779:AUP74 RS00905
gene id: 1769779:AUP74_RS00905
uniprot id: A0A1C9W3C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1769779:AUP74 RS04305
gene id: 1769779:AUP74_RS04305
uniprot id: A0A1C9W599
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS06165
gene id: 1769779:AUP74_RS06165
uniprot id: A0A1C9W6F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1769779:AUP74 RS00755
gene id: 1769779:AUP74_RS00755
uniprot id: A0A1C9W389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS02115
gene id: 1769779:AUP74_RS02115
uniprot id: A0A1C9W421
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1769779:AUP74 RS08785
gene id: 1769779:AUP74_RS08785
uniprot id: A0A1C9W7V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS09380
gene id: 1769779:AUP74_RS09380
uniprot id: A0A1C9W842
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1769779:AUP74 RS02905
gene id: 1769779:AUP74_RS02905
uniprot id: A0A1C9W4I1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS10485
gene id: 1769779:AUP74_RS10485
uniprot id: A0A1C9W8R0
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1769779:AUP74 RS04400
gene id: 1769779:AUP74_RS04400
uniprot id: A0A1C9W5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1769779:AUP74 RS15970
gene id: 1769779:AUP74_RS15970
uniprot id: A0A1C9WBP8
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS11265
gene id: 1769779:AUP74_RS11265
uniprot id: A0A1C9W962
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1769779:AUP74 RS00715
gene id: 1769779:AUP74_RS00715
uniprot id: A0A1C9W385
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS05800
gene id: 1769779:AUP74_RS05800
uniprot id: A0A1C9W657
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1769779:AUP74 RS02425
gene id: 1769779:AUP74_RS02425
uniprot id: A0A1C9W472
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS02260
gene id: 1769779:AUP74_RS02260
uniprot id: A0A1C9W440
names: Similarity
messages: Belongs to the UPF0111 family.

1769779:AUP74 RS09080
gene id: 1769779:AUP74_RS09080
uniprot id: A0A1C9W7Z9
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS08715
gene id: 1769779:AUP74_RS08715
uniprot id: A0A1C9W7T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1769779:AUP74 RS11050
gene id: 1769779:AUP74_RS11050
uniprot id: A0A1C9W913
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1769779:AUP74 RS07345
gene id: 1769779:AUP74_RS07345
uniprot id: A0A1C9W6Z7
names: Similarity
messages: Belongs to the peptidase M24B family.

1769779:AUP74 RS16110
gene id: 1769779:AUP74_RS16110
uniprot id: A0A1C9WBU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS15070
gene id: 1769779:AUP74_RS15070
uniprot id: A0A1C9WB81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1769779:AUP74 RS02950
gene id: 1769779:AUP74_RS02950
uniprot id: A0A1C9W4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS11200
gene id: 1769779:AUP74_RS11200
uniprot id: A0A1C9W928
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1769779:AUP74 RS15435
gene id: 1769779:AUP74_RS15435
uniprot id: A0A1C9WBF1
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1769779:AUP74 RS06765
gene id: 1769779:AUP74_RS06765
uniprot id: A0A1C9W6N3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1769779:AUP74 RS04005
gene id: 1769779:AUP74_RS04005
uniprot id: A0A1C9W557
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1769779:AUP74 RS16545
gene id: 1769779:AUP74_RS16545
uniprot id: A0A1C9WC48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1769779:AUP74 RS13185
gene id: 1769779:AUP74_RS13185
uniprot id: A0A1C9WAC9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1769779:AUP74 RS11085
gene id: 1769779:AUP74_RS11085
uniprot id: A0A1C9W916
names: Similarity
messages: Belongs to the SufE family.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1769779:AUP74 RS01530
gene id: 1769779:AUP74_RS01530
uniprot id: A0A1C9W3Q3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1769779:AUP74 RS05960
gene id: 1769779:AUP74_RS05960
uniprot id: A0A1C9W692
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1769779:AUP74 RS01705
gene id: 1769779:AUP74_RS01705
uniprot id: A0A1C9W3X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1769779:AUP74 RS06950
gene id: 1769779:AUP74_RS06950
uniprot id: A0A1C9W6S5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1769779:AUP74 RS07725
gene id: 1769779:AUP74_RS07725
uniprot id: A0A1C9W768
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1769779:AUP74 RS06425
gene id: 1769779:AUP74_RS06425
uniprot id: A0A1C9W6K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1769779:AUP74 RS09095
gene id: 1769779:AUP74_RS09095
uniprot id: A0A1C9W7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS07040
gene id: 1769779:AUP74_RS07040
uniprot id: A0A1C9W6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1769779:AUP74 RS13965
gene id: 1769779:AUP74_RS13965
uniprot id: A0A1C9WAN3
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS09360
gene id: 1769779:AUP74_RS09360
uniprot id: A0A1C9W858
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1769779:AUP74 RS04545
gene id: 1769779:AUP74_RS04545
uniprot id: A0A1C9W5I7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1769779:AUP74 RS05720
gene id: 1769779:AUP74_RS05720
uniprot id: A0A1C9W649
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1769779:AUP74 RS03205
gene id: 1769779:AUP74_RS03205
uniprot id: A0A1C9W4P4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1769779:AUP74 RS12615
gene id: 1769779:AUP74_RS12615
uniprot id: A0A1C9W9V7
names: Similarity
messages: Belongs to the peptidase A31 family.

1769779:AUP74 RS16205
gene id: 1769779:AUP74_RS16205
uniprot id: A0A1C9WBU9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1769779:AUP74 RS05395
gene id: 1769779:AUP74_RS05395
uniprot id: A0A1C9W606
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS13065
gene id: 1769779:AUP74_RS13065
uniprot id: A0A1C9WA49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1769779:AUP74 RS00700
gene id: 1769779:AUP74_RS00700
uniprot id: A0A1C9W386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS09930
gene id: 1769779:AUP74_RS09930
uniprot id: A0A1C9W8E9
names: Similarity
messages: Belongs to the peptidase S8 family.

1769779:AUP74 RS08950
gene id: 1769779:AUP74_RS08950
uniprot id: A0A1C9W7W3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1769779:AUP74 RS15335
gene id: 1769779:AUP74_RS15335
uniprot id: A0A1C9WBD3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1769779:AUP74 RS12600
gene id: 1769779:AUP74_RS12600
uniprot id: A0A1C9W9V0
names: Similarity
messages: Belongs to the HupF/HypC family.

1769779:AUP74 RS16915
gene id: 1769779:AUP74_RS16915
uniprot id: A0A1C9WC97
names: Similarity
messages: Belongs to the BolA/IbaG family.

1769779:AUP74 RS09510
gene id: 1769779:AUP74_RS09510
uniprot id: A0A1C9W874
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1769779:AUP74 RS02360
gene id: 1769779:AUP74_RS02360
uniprot id: A0A1C9W470
names: Similarity
messages: Belongs to the YkuD family.

1769779:AUP74 RS08550
gene id: 1769779:AUP74_RS08550
uniprot id: A0A1C9W7N3
names: Similarity
messages: Belongs to the peptidase S9A family.

1769779:AUP74 RS07690
gene id: 1769779:AUP74_RS07690
uniprot id: A0A1C9W770
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1769779:AUP74 RS08075
gene id: 1769779:AUP74_RS08075
uniprot id: A0A1C9W7C9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1769779:AUP74 RS00855
gene id: 1769779:AUP74_RS00855
uniprot id: A0A1C9W3C9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1769779:AUP74 RS03875
gene id: 1769779:AUP74_RS03875
uniprot id: A0A1C9W550
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1769779:AUP74 RS15855
gene id: 1769779:AUP74_RS15855
uniprot id: A0A1C9WBM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1769779:AUP74 RS12530
gene id: 1769779:AUP74_RS12530
uniprot id: A0A1C9W9T5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1769779:AUP74 RS02990
gene id: 1769779:AUP74_RS02990
uniprot id: A0A1C9W4L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1769779:AUP74 RS13525
gene id: 1769779:AUP74_RS13525
uniprot id: A0A1C9WAD7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS07660
gene id: 1769779:AUP74_RS07660
uniprot id: A0A1C9W751
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS03085
gene id: 1769779:AUP74_RS03085
uniprot id: A0A1C9W4K5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1769779:AUP74 RS08040
gene id: 1769779:AUP74_RS08040
uniprot id: A0A1C9W7D7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1769779:AUP74 RS13430
gene id: 1769779:AUP74_RS13430
uniprot id: A0A1C9WAD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

1769779:AUP74 RS16795
gene id: 1769779:AUP74_RS16795
uniprot id: A0A1C9WC47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1769779:AUP74 RS09035
gene id: 1769779:AUP74_RS09035
uniprot id: A0A1C9W7X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1769779:AUP74 RS12705
gene id: 1769779:AUP74_RS12705
uniprot id: A0A1C9W9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1769779:AUP74 RS06745
gene id: 1769779:AUP74_RS06745
uniprot id: A0A1C9W6P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1769779:AUP74 RS11890
gene id: 1769779:AUP74_RS11890
uniprot id: A0A1C9W9H8
names: Subcellular Location Annotation
messages: Cytoplasm

1769779:AUP74 RS12995
gene id: 1769779:AUP74_RS12995
uniprot id: A0A1C9WA60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1769779:AUP74 RS00920
gene id: 1769779:AUP74_RS00920
uniprot id: A0A1C9W3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1769779:AUP74 RS16910
gene id: 1769779:AUP74_RS16910
uniprot id: A0A1C9WC75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS12850
gene id: 1769779:AUP74_RS12850
uniprot id: A0A1C9W9Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS15770
gene id: 1769779:AUP74_RS15770
uniprot id: A0A1C9WBM0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1769779:AUP74 RS03845
gene id: 1769779:AUP74_RS03845
uniprot id: A0A1C9W538
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1769779:AUP74 RS11175
gene id: 1769779:AUP74_RS11175
uniprot id: A0A1C9W926
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1769779:AUP74 RS01770
gene id: 1769779:AUP74_RS01770
uniprot id: A0A1C9W3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS08290
gene id: 1769779:AUP74_RS08290
uniprot id: A0A1C9W7G9
names: Similarity
messages: Belongs to the SfsA family.

1769779:AUP74 RS09190
gene id: 1769779:AUP74_RS09190
uniprot id: A0A1C9W824
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1769779:AUP74 RS09130
gene id: 1769779:AUP74_RS09130
uniprot id: A0A1C9W805
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1769779:AUP74 RS08425
gene id: 1769779:AUP74_RS08425
uniprot id: A0A1C9W7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1769779:AUP74 RS02865
gene id: 1769779:AUP74_RS02865
uniprot id: A0A1C9W4H0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1769779:AUP74 RS03585
gene id: 1769779:AUP74_RS03585
uniprot id: A0A1C9W4Y1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS16580
gene id: 1769779:AUP74_RS16580
uniprot id: A0A1C9WC36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1769779:AUP74 RS03490
gene id: 1769779:AUP74_RS03490
uniprot id: A0A1C9W4W3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1769779:AUP74 RS13510
gene id: 1769779:AUP74_RS13510
uniprot id: A0A1C9WAD1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS05560
gene id: 1769779:AUP74_RS05560
uniprot id: A0A1C9W628
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1769779:AUP74 RS14585
gene id: 1769779:AUP74_RS14585
uniprot id: A0A1C9WAZ2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1769779:AUP74 RS16820
gene id: 1769779:AUP74_RS16820
uniprot id: A0A1C9WCA6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1769779:AUP74 RS01180
gene id: 1769779:AUP74_RS01180
uniprot id: A0A1C9W3I1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS10440
gene id: 1769779:AUP74_RS10440
uniprot id: A0A1C9W8R5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1769779:AUP74 RS04255
gene id: 1769779:AUP74_RS04255
uniprot id: A0A1C9W592
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1769779:AUP74 RS10095
gene id: 1769779:AUP74_RS10095
uniprot id: A0A1C9W8K5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1769779:AUP74 RS07125
gene id: 1769779:AUP74_RS07125
uniprot id: A0A1C9W6W4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS10040
gene id: 1769779:AUP74_RS10040
uniprot id: A0A1C9W8H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1769779:AUP74 RS13220
gene id: 1769779:AUP74_RS13220
uniprot id: A0A1C9WA67
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1769779:AUP74 RS06315
gene id: 1769779:AUP74_RS06315
uniprot id: A0A1C9W6F8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1769779:AUP74 RS05965
gene id: 1769779:AUP74_RS05965
uniprot id: A0A1C9W666
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1769779:AUP74 RS06975
gene id: 1769779:AUP74_RS06975
uniprot id: A0A1C9W6U4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1769779:AUP74 RS00565
gene id: 1769779:AUP74_RS00565
uniprot id: A0A1C9W377
names: Similarity
messages: Belongs to the UPF0276 family.

1769779:AUP74 RS00040
gene id: 1769779:AUP74_RS00040
uniprot id: A0A1C9W2W1
names: Subcellular Location Annotation
messages: Cytoplasm

1769779:AUP74 RS04140
gene id: 1769779:AUP74_RS04140
uniprot id: A0A1C9W564
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1769779:AUP74 RS16280
gene id: 1769779:AUP74_RS16280
uniprot id: A0A1C9WBX7
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

1769779:AUP74 RS06885
gene id: 1769779:AUP74_RS06885
uniprot id: A0A1C9W6Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1769779:AUP74 RS02750
gene id: 1769779:AUP74_RS02750
uniprot id: A0A1C9W4F2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS04695
gene id: 1769779:AUP74_RS04695
uniprot id: A0A1C9W5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1769779:AUP74 RS06600
gene id: 1769779:AUP74_RS06600
uniprot id: A0A1C9W6L2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS00995
gene id: 1769779:AUP74_RS00995
uniprot id: A0A1C9W3F0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS02055
gene id: 1769779:AUP74_RS02055
uniprot id: A0A1C9W442
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1769779:AUP74 RS06230
gene id: 1769779:AUP74_RS06230
uniprot id: A0A1C9W6D1
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS02480
gene id: 1769779:AUP74_RS02480
uniprot id: A0A1C9W486
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1769779:AUP74 RS07180
gene id: 1769779:AUP74_RS07180
uniprot id: A0A1C9W6Y9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1769779:AUP74 RS10570
gene id: 1769779:AUP74_RS10570
uniprot id: A0A1C9W8W7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1769779:AUP74 RS01690
gene id: 1769779:AUP74_RS01690
uniprot id: A0A1C9W3S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1769779:AUP74 RS14475
gene id: 1769779:AUP74_RS14475
uniprot id: A0A1C9WAW2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1769779:AUP74 RS10240
gene id: 1769779:AUP74_RS10240
uniprot id: A0A1C9W8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1769779:AUP74 RS06645
gene id: 1769779:AUP74_RS06645
uniprot id: A0A1C9W6L8
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS12590
gene id: 1769779:AUP74_RS12590
uniprot id: A0A1C9W9U8
names: Similarity
messages: Belongs to the HypE family.

1769779:AUP74 RS10000
gene id: 1769779:AUP74_RS10000
uniprot id: A0A1C9W8I7
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS03225
gene id: 1769779:AUP74_RS03225
uniprot id: A0A1C9W4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1769779:AUP74 RS01545
gene id: 1769779:AUP74_RS01545
uniprot id: A0A1C9W3Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1769779:AUP74 RS06115
gene id: 1769779:AUP74_RS06115
uniprot id: A0A1C9W6E3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1769779:AUP74 RS11000
gene id: 1769779:AUP74_RS11000
uniprot id: A0A1C9W8Z6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS09025
gene id: 1769779:AUP74_RS09025
uniprot id: A0A1C9W804
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1769779:AUP74 RS15565
gene id: 1769779:AUP74_RS15565
uniprot id: A0A1C9WBH1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1769779:AUP74 RS15075
gene id: 1769779:AUP74_RS15075
uniprot id: A0A1C9WB82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

1769779:AUP74 RS09275
gene id: 1769779:AUP74_RS09275
uniprot id: A0A1C9W827
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1769779:AUP74 RS02625
gene id: 1769779:AUP74_RS02625
uniprot id: A0A1C9W4B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS06255
gene id: 1769779:AUP74_RS06255
uniprot id: A0A1C9W6E5
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1769779:AUP74 RS05685
gene id: 1769779:AUP74_RS05685
uniprot id: A0A1C9W645
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1769779:AUP74 RS14940
gene id: 1769779:AUP74_RS14940
uniprot id: A0A1C9WB64
names: Similarity
messages: Belongs to the glutamine synthetase family.

1769779:AUP74 RS06070
gene id: 1769779:AUP74_RS06070
uniprot id: A0A1C9W6E0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS16855
gene id: 1769779:AUP74_RS16855
uniprot id: A0A1C9WC76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1769779:AUP74 RS04465
gene id: 1769779:AUP74_RS04465
uniprot id: A0A1C9W5D8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1769779:AUP74 RS01265
gene id: 1769779:AUP74_RS01265
uniprot id: A0A1C9W3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS04015
gene id: 1769779:AUP74_RS04015
uniprot id: A0A1C9W547
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1769779:AUP74 RS02980
gene id: 1769779:AUP74_RS02980
uniprot id: A0A1C9W4I8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1769779:AUP74 RS00250
gene id: 1769779:AUP74_RS00250
uniprot id: A0A1C9W307
names: Similarity
messages: Belongs to the pyruvate kinase family.

1769779:AUP74 RS06510
gene id: 1769779:AUP74_RS06510
uniprot id: A0A1C9W6I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1769779:AUP74 RS16755
gene id: 1769779:AUP74_RS16755
uniprot id: A0A1C9WC46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1769779:AUP74 RS14560
gene id: 1769779:AUP74_RS14560
uniprot id: A0A1C9WAX4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1769779:AUP74 RS12065
gene id: 1769779:AUP74_RS12065
uniprot id: A0A1C9W9L9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1769779:AUP74 RS04855
gene id: 1769779:AUP74_RS04855
uniprot id: A0A1C9W5M3
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS05135
gene id: 1769779:AUP74_RS05135
uniprot id: A0A1C9W5S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1769779:AUP74 RS01490
gene id: 1769779:AUP74_RS01490
uniprot id: A0A1C9W3N8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1769779:AUP74 RS02725
gene id: 1769779:AUP74_RS02725
uniprot id: A0A1C9W4G9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1769779:AUP74 RS03240
gene id: 1769779:AUP74_RS03240
uniprot id: A0A1C9W4P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1769779:AUP74 RS16190
gene id: 1769779:AUP74_RS16190
uniprot id: A0A1C9WBU6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1769779:AUP74 RS02095
gene id: 1769779:AUP74_RS02095
uniprot id: A0A1C9W419
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1769779:AUP74 RS06790
gene id: 1769779:AUP74_RS06790
uniprot id: A0A1C9W6R6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1769779:AUP74 RS08960
gene id: 1769779:AUP74_RS08960
uniprot id: A0A1C9W7W4
names: Subcellular Location Annotation
messages: Cytoplasm

1769779:AUP74 RS12805
gene id: 1769779:AUP74_RS12805
uniprot id: A0A1C9W9Z3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1769779:AUP74 RS04525
gene id: 1769779:AUP74_RS04525
uniprot id: A0A1C9W5H1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1769779:AUP74 RS12165
gene id: 1769779:AUP74_RS12165
uniprot id: A0A1C9W9L8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1769779:AUP74 RS14155
gene id: 1769779:AUP74_RS14155
uniprot id: A0A1C9WAR6
names: Similarity
messages: Belongs to the TPP enzyme family.

1769779:AUP74 RS01880
gene id: 1769779:AUP74_RS01880
uniprot id: A0A1C9W3W9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1769779:AUP74 RS09245
gene id: 1769779:AUP74_RS09245
uniprot id: A0A1C9W835
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS00875
gene id: 1769779:AUP74_RS00875
uniprot id: A0A1C9W3C2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1769779:AUP74 RS09125
gene id: 1769779:AUP74_RS09125
uniprot id: A0A1C9W828
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1769779:AUP74 RS16000
gene id: 1769779:AUP74_RS16000
uniprot id: A0A1C9WBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1769779:AUP74 RS03890
gene id: 1769779:AUP74_RS03890
uniprot id: A0A1C9W508
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

1769779:AUP74 RS07170
gene id: 1769779:AUP74_RS07170
uniprot id: A0A1C9W6X7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS04710
gene id: 1769779:AUP74_RS04710
uniprot id: A0A1C9W5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1769779:AUP74 RS08360
gene id: 1769779:AUP74_RS08360
uniprot id: A0A1C9W7K4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1769779:AUP74 RS02365
gene id: 1769779:AUP74_RS02365
uniprot id: A0A1C9W481
names: Similarity
messages: Belongs to the YkuD family.

1769779:AUP74 RS12240
gene id: 1769779:AUP74_RS12240
uniprot id: A0A1C9W9M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1769779:AUP74 RS00890
gene id: 1769779:AUP74_RS00890
uniprot id: A0A1C9W3D4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1769779:AUP74 RS03895
gene id: 1769779:AUP74_RS03895
uniprot id: A0A1C9W546
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1769779:AUP74 RS00090
gene id: 1769779:AUP74_RS00090
uniprot id: A0A1C9W2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1769779:AUP74 RS02345
gene id: 1769779:AUP74_RS02345
uniprot id: A0A1C9W468
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS04565
gene id: 1769779:AUP74_RS04565
uniprot id: A0A1C9W5F3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1769779:AUP74 RS01855
gene id: 1769779:AUP74_RS01855
uniprot id: A0A1C9W3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1769779:AUP74 RS16490
gene id: 1769779:AUP74_RS16490
uniprot id: A0A1C9WC00
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1769779:AUP74 RS11730
gene id: 1769779:AUP74_RS11730
uniprot id: A0A1C9W9C6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1769779:AUP74 RS12125
gene id: 1769779:AUP74_RS12125
uniprot id: A0A1C9W9Q3
names: Similarity
messages: Belongs to the AHA1 family.

1769779:AUP74 RS14735
gene id: 1769779:AUP74_RS14735
uniprot id: A0A1C9WB12
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS02320
gene id: 1769779:AUP74_RS02320
uniprot id: A0A1C9W452
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1769779:AUP74 RS00930
gene id: 1769779:AUP74_RS00930
uniprot id: A0A1C9W3C8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1769779:AUP74 RS03080
gene id: 1769779:AUP74_RS03080
uniprot id: A0A1C9W4L2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1769779:AUP74 RS07045
gene id: 1769779:AUP74_RS07045
uniprot id: A0A1C9W6U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS09745
gene id: 1769779:AUP74_RS09745
uniprot id: A0A1C9W8D4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1769779:AUP74 RS02405
gene id: 1769779:AUP74_RS02405
uniprot id: A0A1C9W482
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1769779:AUP74 RS04245
gene id: 1769779:AUP74_RS04245
uniprot id: A0A1C9W587
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1769779:AUP74 RS01795
gene id: 1769779:AUP74_RS01795
uniprot id: A0A1C9W3V6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1769779:AUP74 RS16255
gene id: 1769779:AUP74_RS16255
uniprot id: A0A1C9WBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS12500
gene id: 1769779:AUP74_RS12500
uniprot id: A0A1C9W9T3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1769779:AUP74 RS07005
gene id: 1769779:AUP74_RS07005
uniprot id: A0A1C9W6T2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1769779:AUP74 RS06260
gene id: 1769779:AUP74_RS06260
uniprot id: A0A1C9W6E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS11410
gene id: 1769779:AUP74_RS11410
uniprot id: A0A1C9W999
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1769779:AUP74 RS16070
gene id: 1769779:AUP74_RS16070
uniprot id: A0A1C9WBR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1769779:AUP74 RS08995
gene id: 1769779:AUP74_RS08995
uniprot id: A0A1C9W7W0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1769779:AUP74 RS14545
gene id: 1769779:AUP74_RS14545
uniprot id: A0A1C9WAX1
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS04470
gene id: 1769779:AUP74_RS04470
uniprot id: A0A1C9W5E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1769779:AUP74 RS02000
gene id: 1769779:AUP74_RS02000
uniprot id: A0A1C9W435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1769779:AUP74 RS08930
gene id: 1769779:AUP74_RS08930
uniprot id: A0A1C9W7Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1769779:AUP74 RS00535
gene id: 1769779:AUP74_RS00535
uniprot id: A0A1C9W353
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1769779:AUP74 RS06865
gene id: 1769779:AUP74_RS06865
uniprot id: A0A1C9W6Q3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1769779:AUP74 RS11955
gene id: 1769779:AUP74_RS11955
uniprot id: A0A1C9W9N8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1769779:AUP74 RS04200
gene id: 1769779:AUP74_RS04200
uniprot id: A0A1C9W579
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS11205
gene id: 1769779:AUP74_RS11205
uniprot id: A0A1C9W946
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1769779:AUP74 RS08450
gene id: 1769779:AUP74_RS08450
uniprot id: A0A1C9W7L8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1769779:AUP74 RS03525
gene id: 1769779:AUP74_RS03525
uniprot id: A0A1C9W4W6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1769779:AUP74 RS13405
gene id: 1769779:AUP74_RS13405
uniprot id: A0A1C9WAC2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS11735
gene id: 1769779:AUP74_RS11735
uniprot id: A0A1C9W9D4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1769779:AUP74 RS05945
gene id: 1769779:AUP74_RS05945
uniprot id: A0A1C9W683
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1769779:AUP74 RS02350
gene id: 1769779:AUP74_RS02350
uniprot id: A0A1C9W489
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1769779:AUP74 RS01560
gene id: 1769779:AUP74_RS01560
uniprot id: A0A1C9W3R9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1769779:AUP74 RS02370
gene id: 1769779:AUP74_RS02370
uniprot id: A0A1C9W461
names: Similarity
messages: Belongs to the YkuD family.

1769779:AUP74 RS12170
gene id: 1769779:AUP74_RS12170
uniprot id: A0A1C9W9T2
names: Similarity
messages: Belongs to the PrpD family.

1769779:AUP74 RS02760
gene id: 1769779:AUP74_RS02760
uniprot id: A0A1C9W4E0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS02765
gene id: 1769779:AUP74_RS02765
uniprot id: A0A1C9W4E7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1769779:AUP74 RS05265
gene id: 1769779:AUP74_RS05265
uniprot id: A0A1C9W5V9
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS09140
gene id: 1769779:AUP74_RS09140
uniprot id: A0A1C9W814
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1769779:AUP74 RS13320
gene id: 1769779:AUP74_RS13320
uniprot id: A0A1C9WA87
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1769779:AUP74 RS03685
gene id: 1769779:AUP74_RS03685
uniprot id: A0A1C9W4X5
names: Similarity
messages: Belongs to the peptidase S9A family.

1769779:AUP74 RS01205
gene id: 1769779:AUP74_RS01205
uniprot id: A0A1C9W3K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS02910
gene id: 1769779:AUP74_RS02910
uniprot id: A0A1C9W4H9
names: Similarity
messages: Belongs to the peptidase M16 family.

1769779:AUP74 RS16675
gene id: 1769779:AUP74_RS16675
uniprot id: A0A1C9WC33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1769779:AUP74 RS15635
gene id: 1769779:AUP74_RS15635
uniprot id: A0A1C9WBJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS15270
gene id: 1769779:AUP74_RS15270
uniprot id: A0A1C9WBB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS07225
gene id: 1769779:AUP74_RS07225
uniprot id: A0A1C9W6Y3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS12355
gene id: 1769779:AUP74_RS12355
uniprot id: A0A1C9W9P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS15765
gene id: 1769779:AUP74_RS15765
uniprot id: A0A1C9WBL8
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS02340
gene id: 1769779:AUP74_RS02340
uniprot id: A0A1C9W474
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1769779:AUP74 RS00945
gene id: 1769779:AUP74_RS00945
uniprot id: A0A1C9W3E0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1769779:AUP74 RS13060
gene id: 1769779:AUP74_RS13060
uniprot id: A0A1C9WA43
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1769779:AUP74 RS06615
gene id: 1769779:AUP74_RS06615
uniprot id: A0A1C9W6L6
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS16140
gene id: 1769779:AUP74_RS16140
uniprot id: A0A1C9WBS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1769779:AUP74 RS03790
gene id: 1769779:AUP74_RS03790
uniprot id: A0A1C9W4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1769779:AUP74 RS04510
gene id: 1769779:AUP74_RS04510
uniprot id: A0A1C9W5I2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1769779:AUP74 RS04150
gene id: 1769779:AUP74_RS04150
uniprot id: A0A1C9W567
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1769779:AUP74 RS15470
gene id: 1769779:AUP74_RS15470
uniprot id: A0A1C9WBE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1769779:AUP74 RS06325
gene id: 1769779:AUP74_RS06325
uniprot id: A0A1C9W6H9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1769779:AUP74 RS12115
gene id: 1769779:AUP74_RS12115
uniprot id: A0A1C9W9S5
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS14345
gene id: 1769779:AUP74_RS14345
uniprot id: A0A1C9WAT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1769779:AUP74 RS06395
gene id: 1769779:AUP74_RS06395
uniprot id: A0A1C9W6H3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1769779:AUP74 RS08815
gene id: 1769779:AUP74_RS08815
uniprot id: A0A1C9W7T4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1769779:AUP74 RS00740
gene id: 1769779:AUP74_RS00740
uniprot id: A0A1C9W3A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

1769779:AUP74 RS05310
gene id: 1769779:AUP74_RS05310
uniprot id: A0A1C9W5W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1769779:AUP74 RS01700
gene id: 1769779:AUP74_RS01700
uniprot id: A0A1C9W3T3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1769779:AUP74 RS11300
gene id: 1769779:AUP74_RS11300
uniprot id: A0A1C9W953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1769779:AUP74 RS16260
gene id: 1769779:AUP74_RS16260
uniprot id: A0A1C9WBX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1769779:AUP74 RS05860
gene id: 1769779:AUP74_RS05860
uniprot id: A0A1C9W697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1769779:AUP74 RS06840
gene id: 1769779:AUP74_RS06840
uniprot id: A0A1C9W6S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1769779:AUP74 RS16175
gene id: 1769779:AUP74_RS16175
uniprot id: A0A1C9WBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1769779:AUP74 RS06040
gene id: 1769779:AUP74_RS06040
uniprot id: A0A1C9W6A2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1769779:AUP74 RS06485
gene id: 1769779:AUP74_RS06485
uniprot id: A0A1C9W6I3
names: Similarity
messages: Belongs to the GARS family.

1769779:AUP74 RS06640
gene id: 1769779:AUP74_RS06640
uniprot id: A0A1C9W6P2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1769779:AUP74 RS12335
gene id: 1769779:AUP74_RS12335
uniprot id: A0A1C9W9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS08865
gene id: 1769779:AUP74_RS08865
uniprot id: A0A1C9W7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1769779:AUP74 RS12845
gene id: 1769779:AUP74_RS12845
uniprot id: A0A1C9WA32
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1769779:AUP74 RS00975
gene id: 1769779:AUP74_RS00975
uniprot id: A0A1C9W3E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1769779:AUP74 RS02740
gene id: 1769779:AUP74_RS02740
uniprot id: A0A1C9W4F8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1769779:AUP74 RS04950
gene id: 1769779:AUP74_RS04950
uniprot id: A0A1C9W5P4
names: Similarity
messages: Belongs to the PspA/IM30 family.

1769779:AUP74 RS04095
gene id: 1769779:AUP74_RS04095
uniprot id: A0A1C9W593
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1769779:AUP74 RS13135
gene id: 1769779:AUP74_RS13135
uniprot id: A0A1C9WAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS04025
gene id: 1769779:AUP74_RS04025
uniprot id: A0A1C9W577
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1769779:AUP74 RS13345
gene id: 1769779:AUP74_RS13345
uniprot id: A0A1C9WAC0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1769779:AUP74 RS07155
gene id: 1769779:AUP74_RS07155
uniprot id: A0A1C9W6W5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS09870
gene id: 1769779:AUP74_RS09870
uniprot id: A0A1C9W8F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1769779:AUP74 RS06895
gene id: 1769779:AUP74_RS06895
uniprot id: A0A1C9W6Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1769779:AUP74 RS08250
gene id: 1769779:AUP74_RS08250
uniprot id: A0A1C9W7G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1769779:AUP74 RS15320
gene id: 1769779:AUP74_RS15320
uniprot id: A0A1C9WBC0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1769779:AUP74 RS04320
gene id: 1769779:AUP74_RS04320
uniprot id: A0A1C9W5A8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1769779:AUP74 RS01875
gene id: 1769779:AUP74_RS01875
uniprot id: A0A1C9W3X3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1769779:AUP74 RS01485
gene id: 1769779:AUP74_RS01485
uniprot id: A0A1C9W3P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1769779:AUP74 RS09675
gene id: 1769779:AUP74_RS09675
uniprot id: A0A1C9W8A1
names: Similarity
messages: Belongs to the catalase family.

1769779:AUP74 RS16470
gene id: 1769779:AUP74_RS16470
uniprot id: A0A1C9WBZ7
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS11065
gene id: 1769779:AUP74_RS11065
uniprot id: A0A1C9W934
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1769779:AUP74 RS02085
gene id: 1769779:AUP74_RS02085
uniprot id: A0A1C9W406
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1769779:AUP74 RS05425
gene id: 1769779:AUP74_RS05425
uniprot id: A0A1C9W604
names: Similarity
messages: Belongs to the P(II) protein family.

1769779:AUP74 RS15580
gene id: 1769779:AUP74_RS15580
uniprot id: A0A1C9WBH2
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS16765
gene id: 1769779:AUP74_RS16765
uniprot id: A0A1C9WC95
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1769779:AUP74 RS15340
gene id: 1769779:AUP74_RS15340
uniprot id: A0A1C9WBD2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1769779:AUP74 RS15615
gene id: 1769779:AUP74_RS15615
uniprot id: A0A1C9WBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1769779:AUP74 RS13705
gene id: 1769779:AUP74_RS13705
uniprot id: A0A1C9WAH3
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1769779:AUP74 RS07085
gene id: 1769779:AUP74_RS07085
uniprot id: A0A1C9W6V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1769779:AUP74 RS02250
gene id: 1769779:AUP74_RS02250
uniprot id: A0A1C9W477
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1769779:AUP74 RS08615
gene id: 1769779:AUP74_RS08615
uniprot id: A0A1C9W7R8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1769779:AUP74 RS03640
gene id: 1769779:AUP74_RS03640
uniprot id: A0A1C9W4Z7
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS10895
gene id: 1769779:AUP74_RS10895
uniprot id: A0A1C9W8Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1769779:AUP74 RS06995
gene id: 1769779:AUP74_RS06995
uniprot id: A0A1C9W6T7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1769779:AUP74 RS09260
gene id: 1769779:AUP74_RS09260
uniprot id: A0A1C9W834
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1769779:AUP74 RS07565
gene id: 1769779:AUP74_RS07565
uniprot id: A0A1C9W730
names: Similarity
messages: Belongs to the UPF0145 family.

1769779:AUP74 RS08085
gene id: 1769779:AUP74_RS08085
uniprot id: A0A1C9W7D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1769779:AUP74 RS09990
gene id: 1769779:AUP74_RS09990
uniprot id: A0A1C9W8G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS05675
gene id: 1769779:AUP74_RS05675
uniprot id: A0A1C9W653
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1769779:AUP74 RS06925
gene id: 1769779:AUP74_RS06925
uniprot id: A0A1C9W6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1769779:AUP74 RS10220
gene id: 1769779:AUP74_RS10220
uniprot id: A0A1C9W8L8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1769779:AUP74 RS09220
gene id: 1769779:AUP74_RS09220
uniprot id: A0A1C9W813
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

1769779:AUP74 RS03990
gene id: 1769779:AUP74_RS03990
uniprot id: A0A1C9W531
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1769779:AUP74 RS06495
gene id: 1769779:AUP74_RS06495
uniprot id: A0A1C9W6J1
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1769779:AUP74 RS14525
gene id: 1769779:AUP74_RS14525
uniprot id: A0A1C9WAX6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1769779:AUP74 RS04110
gene id: 1769779:AUP74_RS04110
uniprot id: A0A1C9W5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1769779:AUP74 RS10225
gene id: 1769779:AUP74_RS10225
uniprot id: A0A1C9W8K6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1769779:AUP74 RS12905
gene id: 1769779:AUP74_RS12905
uniprot id: A0A1C9WA20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1769779:AUP74 RS07370
gene id: 1769779:AUP74_RS07370
uniprot id: A0A1C9W703
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1769779:AUP74 RS05070
gene id: 1769779:AUP74_RS05070
uniprot id: A0A1C9W5T0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1769779:AUP74 RS07505
gene id: 1769779:AUP74_RS07505
uniprot id: A0A1C9W727
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1769779:AUP74 RS14335
gene id: 1769779:AUP74_RS14335
uniprot id: A0A1C9WAS9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1769779:AUP74 RS05680
gene id: 1769779:AUP74_RS05680
uniprot id: A0A1C9W623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1769779:AUP74 RS13175
gene id: 1769779:AUP74_RS13175
uniprot id: A0A1C9WA70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1769779:AUP74 RS00490
gene id: 1769779:AUP74_RS00490
uniprot id: A0A1C9W345
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1769779:AUP74 RS00255
gene id: 1769779:AUP74_RS00255
uniprot id: A0A1C9W304
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1769779:AUP74 RS02025
gene id: 1769779:AUP74_RS02025
uniprot id: A0A1C9W3Z2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1769779:AUP74 RS16430
gene id: 1769779:AUP74_RS16430
uniprot id: A0A1C9WC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1769779:AUP74 RS16685
gene id: 1769779:AUP74_RS16685
uniprot id: A0A1C9WC51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1769779:AUP74 RS02215
gene id: 1769779:AUP74_RS02215
uniprot id: A0A1C9W439
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1769779:AUP74 RS06770
gene id: 1769779:AUP74_RS06770
uniprot id: A0A1C9W6N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1769779:AUP74 RS12620
gene id: 1769779:AUP74_RS12620
uniprot id: A0A1C9W9V9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1769779:AUP74 RS00100
gene id: 1769779:AUP74_RS00100
uniprot id: A0A1C9W2X1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1769779:AUP74 RS16285
gene id: 1769779:AUP74_RS16285
uniprot id: A0A1C9WBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1769779:AUP74 RS04530
gene id: 1769779:AUP74_RS04530
uniprot id: A0A1C9W5E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1769779:AUP74 RS04135
gene id: 1769779:AUP74_RS04135
uniprot id: A0A1C9W575
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS14570
gene id: 1769779:AUP74_RS14570
uniprot id: A0A1C9WAZ3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.
messages: Belongs to the rubredoxin family.

1769779:AUP74 RS00195
gene id: 1769779:AUP74_RS00195
uniprot id: A0A1C9W2Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1769779:AUP74 RS00245
gene id: 1769779:AUP74_RS00245
uniprot id: A0A1C9W2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS03505
gene id: 1769779:AUP74_RS03505
uniprot id: A0A1C9W4T8
names: Similarity
messages: Belongs to the HSP15 family.

1769779:AUP74 RS09160
gene id: 1769779:AUP74_RS09160
uniprot id: A0A1C9W812
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1769779:AUP74 RS02620
gene id: 1769779:AUP74_RS02620
uniprot id: A0A1C9W4B6
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS04235
gene id: 1769779:AUP74_RS04235
uniprot id: A0A1C9W574
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1769779:AUP74 RS07700
gene id: 1769779:AUP74_RS07700
uniprot id: A0A1C9W752
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1769779:AUP74 RS00280
gene id: 1769779:AUP74_RS00280
uniprot id: A0A1C9W308
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1769779:AUP74 RS05450
gene id: 1769779:AUP74_RS05450
uniprot id: A0A1C9W600
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS06055
gene id: 1769779:AUP74_RS06055
uniprot id: A0A1C9W6B0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1769779:AUP74 RS11590
gene id: 1769779:AUP74_RS11590
uniprot id: A0A1C9W9E0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1769779:AUP74 RS11860
gene id: 1769779:AUP74_RS11860
uniprot id: A0A1C9W9H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1769779:AUP74 RS15040
gene id: 1769779:AUP74_RS15040
uniprot id: A0A1C9WB93
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1769779:AUP74 RS14715
gene id: 1769779:AUP74_RS14715
uniprot id: A0A1C9WB06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1769779:AUP74 RS13970
gene id: 1769779:AUP74_RS13970
uniprot id: A0A1C9WAN6
names: Similarity
messages: Belongs to the peptidase S66 family.

1769779:AUP74 RS07295
gene id: 1769779:AUP74_RS07295
uniprot id: A0A1C9W6Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1769779:AUP74 RS05205
gene id: 1769779:AUP74_RS05205
uniprot id: A0A1C9W5V6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1769779:AUP74 RS10765
gene id: 1769779:AUP74_RS10765
uniprot id: A0A1C9W8U9
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS09840
gene id: 1769779:AUP74_RS09840
uniprot id: A0A1C9W8D5
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1769779:AUP74 RS15385
gene id: 1769779:AUP74_RS15385
uniprot id: A0A1C9WBE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1769779:AUP74 RS03855
gene id: 1769779:AUP74_RS03855
uniprot id: A0A1C9W533
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1769779:AUP74 RS16925
gene id: 1769779:AUP74_RS16925
uniprot id: A0A1C9WC98
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS09890
gene id: 1769779:AUP74_RS09890
uniprot id: A0A1C9W8E3
names: Similarity
messages: Belongs to the TlyA family.

1769779:AUP74 RS15985
gene id: 1769779:AUP74_RS15985
uniprot id: A0A1C9WBR6
names: Similarity
messages: Belongs to the ArsC family.

1769779:AUP74 RS03565
gene id: 1769779:AUP74_RS03565
uniprot id: A0A1C9W4W0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1769779:AUP74 RS10070
gene id: 1769779:AUP74_RS10070
uniprot id: A0A1C9W8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1769779:AUP74 RS09090
gene id: 1769779:AUP74_RS09090
uniprot id: A0A1C9W806
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1769779:AUP74 RS15420
gene id: 1769779:AUP74_RS15420
uniprot id: A0A1C9WBE0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1769779:AUP74 RS08280
gene id: 1769779:AUP74_RS08280
uniprot id: A0A1C9W7H6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS01970
gene id: 1769779:AUP74_RS01970
uniprot id: A0A1C9W3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS08380
gene id: 1769779:AUP74_RS08380
uniprot id: A0A1C9W7L0
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS12900
gene id: 1769779:AUP74_RS12900
uniprot id: A0A1C9WA06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1769779:AUP74 RS13070
gene id: 1769779:AUP74_RS13070
uniprot id: A0A1C9WA33
names: Similarity
messages: Belongs to the fabD family.

1769779:AUP74 RS16750
gene id: 1769779:AUP74_RS16750
uniprot id: A0A1C9WC59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS16050
gene id: 1769779:AUP74_RS16050
uniprot id: A0A1C9WBQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS14975
gene id: 1769779:AUP74_RS14975
uniprot id: A0A1C9WB65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS12810
gene id: 1769779:AUP74_RS12810
uniprot id: A0A1C9W9Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1769779:AUP74 RS03730
gene id: 1769779:AUP74_RS03730
uniprot id: A0A1C9W4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1769779:AUP74 RS03945
gene id: 1769779:AUP74_RS03945
uniprot id: A0A1C9W558
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1769779:AUP74 RS12425
gene id: 1769779:AUP74_RS12425
uniprot id: A0A1C9W9Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS04810
gene id: 1769779:AUP74_RS04810
uniprot id: A0A1C9W5N3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1769779:AUP74 RS06880
gene id: 1769779:AUP74_RS06880
uniprot id: A0A1C9W6T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1769779:AUP74 RS09010
gene id: 1769779:AUP74_RS09010
uniprot id: A0A1C9W7X6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1769779:AUP74 RS04355
gene id: 1769779:AUP74_RS04355
uniprot id: A0A1C9W5B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1769779:AUP74 RS09000
gene id: 1769779:AUP74_RS09000
uniprot id: A0A1C9W7X2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1769779:AUP74 RS13285
gene id: 1769779:AUP74_RS13285
uniprot id: A0A1C9WAF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1769779:AUP74 RS12210
gene id: 1769779:AUP74_RS12210
uniprot id: A0A1C9W9M1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1769779:AUP74 RS12740
gene id: 1769779:AUP74_RS12740
uniprot id: A0A1C9W9X8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1769779:AUP74 RS04180
gene id: 1769779:AUP74_RS04180
uniprot id: A0A1C9W566
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1769779:AUP74 RS16680
gene id: 1769779:AUP74_RS16680
uniprot id: A0A1C9WC62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1769779:AUP74 RS15775
gene id: 1769779:AUP74_RS15775
uniprot id: A0A1C9WBL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS03925
gene id: 1769779:AUP74_RS03925
uniprot id: A0A1C9W563
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1769779:AUP74 RS04640
gene id: 1769779:AUP74_RS04640
uniprot id: A0A1C9W5H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS12795
gene id: 1769779:AUP74_RS12795
uniprot id: A0A1C9WA21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1769779:AUP74 RS04050
gene id: 1769779:AUP74_RS04050
uniprot id: A0A1C9W551
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1769779:AUP74 RS12540
gene id: 1769779:AUP74_RS12540
uniprot id: A0A1C9W9U1
names: Similarity
messages: Belongs to the TPP enzyme family.

1769779:AUP74 RS14080
gene id: 1769779:AUP74_RS14080
uniprot id: A0A1C9WAR3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS13680
gene id: 1769779:AUP74_RS13680
uniprot id: A0A1C9WAI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1769779:AUP74 RS08395
gene id: 1769779:AUP74_RS08395
uniprot id: A0A1C9W7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS11215
gene id: 1769779:AUP74_RS11215
uniprot id: A0A1C9W955
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1769779:AUP74 RS08240
gene id: 1769779:AUP74_RS08240
uniprot id: A0A1C9W7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1769779:AUP74 RS06415
gene id: 1769779:AUP74_RS06415
uniprot id: A0A1C9W6I5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1769779:AUP74 RS05760
gene id: 1769779:AUP74_RS05760
uniprot id: A0A1C9W673
names: Similarity
messages: Belongs to the glutamate synthase family.

1769779:AUP74 RS05820
gene id: 1769779:AUP74_RS05820
uniprot id: A0A1C9W671
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1769779:AUP74 RS14310
gene id: 1769779:AUP74_RS14310
uniprot id: A0A1C9WAS2
names: Similarity
messages: Belongs to the PucC family.

1769779:AUP74 RS05180
gene id: 1769779:AUP74_RS05180
uniprot id: A0A1C9W5T1
names: Similarity
messages: Belongs to the LOG family.

1769779:AUP74 RS08420
gene id: 1769779:AUP74_RS08420
uniprot id: A0A1C9W7M5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1769779:AUP74 RS16510
gene id: 1769779:AUP74_RS16510
uniprot id: A0A1C9WC26
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1769779:AUP74 RS05175
gene id: 1769779:AUP74_RS05175
uniprot id: A0A1C9W5T2
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1769779:AUP74 RS06875
gene id: 1769779:AUP74_RS06875
uniprot id: A0A1C9W6S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1769779:AUP74 RS16525
gene id: 1769779:AUP74_RS16525
uniprot id: A0A1C9WC01
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1769779:AUP74 RS02395
gene id: 1769779:AUP74_RS02395
uniprot id: A0A1C9W480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1769779:AUP74 RS08475
gene id: 1769779:AUP74_RS08475
uniprot id: A0A1C9W7K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS12025
gene id: 1769779:AUP74_RS12025
uniprot id: A0A1C9W9I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1769779:AUP74 RS10665
gene id: 1769779:AUP74_RS10665
uniprot id: A0A1C9W8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS00420
gene id: 1769779:AUP74_RS00420
uniprot id: A0A1C9W338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1769779:AUP74 RS02770
gene id: 1769779:AUP74_RS02770
uniprot id: A0A1C9W4F4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS06775
gene id: 1769779:AUP74_RS06775
uniprot id: A0A1C9W6Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1769779:AUP74 RS16900
gene id: 1769779:AUP74_RS16900
uniprot id: A0A1C9WCD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1769779:AUP74 RS06635
gene id: 1769779:AUP74_RS06635
uniprot id: A0A1C9W6M4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1769779:AUP74 RS12715
gene id: 1769779:AUP74_RS12715
uniprot id: A0A1C9W9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1769779:AUP74 RS03745
gene id: 1769779:AUP74_RS03745
uniprot id: A0A1C9W526
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS09530
gene id: 1769779:AUP74_RS09530
uniprot id: A0A1C9W870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS16700
gene id: 1769779:AUP74_RS16700
uniprot id: A0A1C9WC49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1769779:AUP74 RS10280
gene id: 1769779:AUP74_RS10280
uniprot id: A0A1C9W8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1769779:AUP74 RS00940
gene id: 1769779:AUP74_RS00940
uniprot id: A0A1C9W3E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1769779:AUP74 RS03885
gene id: 1769779:AUP74_RS03885
uniprot id: A0A1C9W534
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS00010
gene id: 1769779:AUP74_RS00010
uniprot id: A0A1C9W2W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1769779:AUP74 RS13930
gene id: 1769779:AUP74_RS13930
uniprot id: A0A1C9WAM1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1769779:AUP74 RS03095
gene id: 1769779:AUP74_RS03095
uniprot id: A0A1C9W4L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1769779:AUP74 RS11705
gene id: 1769779:AUP74_RS11705
uniprot id: A0A1C9W9I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS15650
gene id: 1769779:AUP74_RS15650
uniprot id: A0A1C9WBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1769779:AUP74 RS06940
gene id: 1769779:AUP74_RS06940
uniprot id: A0A1C9W6U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1769779:AUP74 RS04350
gene id: 1769779:AUP74_RS04350
uniprot id: A0A1C9W5D5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1769779:AUP74 RS00860
gene id: 1769779:AUP74_RS00860
uniprot id: A0A1C9W3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1769779:AUP74 RS00620
gene id: 1769779:AUP74_RS00620
uniprot id: A0A1C9W372
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1769779:AUP74 RS04385
gene id: 1769779:AUP74_RS04385
uniprot id: A0A1C9W5B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1769779:AUP74 RS00800
gene id: 1769779:AUP74_RS00800
uniprot id: A0A1C9W3A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1769779:AUP74 RS10080
gene id: 1769779:AUP74_RS10080
uniprot id: A0A1C9W8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1769779:AUP74 RS08645
gene id: 1769779:AUP74_RS08645
uniprot id: A0A1C9W7P8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS16440
gene id: 1769779:AUP74_RS16440
uniprot id: A0A1C9WBZ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1769779:AUP74 RS01330
gene id: 1769779:AUP74_RS01330
uniprot id: A0A1C9W3L2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1769779:AUP74 RS15610
gene id: 1769779:AUP74_RS15610
uniprot id: A0A1C9WBI4
names: Similarity
messages: Belongs to the Skp family.

1769779:AUP74 RS06185
gene id: 1769779:AUP74_RS06185
uniprot id: A0A1C9W6C3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS06795
gene id: 1769779:AUP74_RS06795
uniprot id: A0A1C9W6P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1769779:AUP74 RS16340
gene id: 1769779:AUP74_RS16340
uniprot id: A0A1C9WBW9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1769779:AUP74 RS05090
gene id: 1769779:AUP74_RS05090
uniprot id: A0A1C9W5T8
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1769779:AUP74 RS11100
gene id: 1769779:AUP74_RS11100
uniprot id: A0A1C9W932
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1769779:AUP74 RS14025
gene id: 1769779:AUP74_RS14025
uniprot id: A0A1C9WAP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1769779:AUP74 RS04585
gene id: 1769779:AUP74_RS04585
uniprot id: A0A1C9W5G2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1769779:AUP74 RS07100
gene id: 1769779:AUP74_RS07100
uniprot id: A0A1C9W6V6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS01620
gene id: 1769779:AUP74_RS01620
uniprot id: A0A1C9W3T1
names: Similarity
messages: Belongs to the HIBADH-related family.

1769779:AUP74 RS05385
gene id: 1769779:AUP74_RS05385
uniprot id: A0A1C9W5X0
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1769779:AUP74 RS02265
gene id: 1769779:AUP74_RS02265
uniprot id: A0A1C9W449
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1769779:AUP74 RS10065
gene id: 1769779:AUP74_RS10065
uniprot id: A0A1C9W8K0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS06855
gene id: 1769779:AUP74_RS06855
uniprot id: A0A1C9W6Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1769779:AUP74 RS04370
gene id: 1769779:AUP74_RS04370
uniprot id: A0A1C9W5B3
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS14745
gene id: 1769779:AUP74_RS14745
uniprot id: A0A1C9WB20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1769779:AUP74 RS03265
gene id: 1769779:AUP74_RS03265
uniprot id: A0A1C9W4Q0
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1769779:AUP74 RS00160
gene id: 1769779:AUP74_RS00160
uniprot id: A0A1C9W2Z1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1769779:AUP74 RS10235
gene id: 1769779:AUP74_RS10235
uniprot id: A0A1C9W8L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1769779:AUP74 RS13235
gene id: 1769779:AUP74_RS13235
uniprot id: A0A1C9WAE3
names: Similarity
messages: Belongs to the thioredoxin family.

1769779:AUP74 RS16520
gene id: 1769779:AUP74_RS16520
uniprot id: A0A1C9WC11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1769779:AUP74 RS00295
gene id: 1769779:AUP74_RS00295
uniprot id: A0A1C9W309
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1769779:AUP74 RS04890
gene id: 1769779:AUP74_RS04890
uniprot id: A0A1C9W5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1769779:AUP74 RS00525
gene id: 1769779:AUP74_RS00525
uniprot id: A0A1C9W354
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1769779:AUP74 RS06935
gene id: 1769779:AUP74_RS06935
uniprot id: A0A1C9W6R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1769779:AUP74 RS01470
gene id: 1769779:AUP74_RS01470
uniprot id: A0A1C9W3N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1769779:AUP74 RS16610
gene id: 1769779:AUP74_RS16610
uniprot id: A0A1C9WC54
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1769779:AUP74 RS04035
gene id: 1769779:AUP74_RS04035
uniprot id: A0A1C9W555
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1769779:AUP74 RS00370
gene id: 1769779:AUP74_RS00370
uniprot id: A0A1C9W331
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1769779:AUP74 RS11360
gene id: 1769779:AUP74_RS11360
uniprot id: A0A1C9W986
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1769779:AUP74 RS16715
gene id: 1769779:AUP74_RS16715
uniprot id: A0A1C9WC86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1769779:AUP74 RS07020
gene id: 1769779:AUP74_RS07020
uniprot id: A0A1C9W6T5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1769779:AUP74 RS15630
gene id: 1769779:AUP74_RS15630
uniprot id: A0A1C9WBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1769779:AUP74 RS15885
gene id: 1769779:AUP74_RS15885
uniprot id: A0A1C9WBP0
names: Similarity
messages: Belongs to the glutamate synthase family.

1769779:AUP74 RS15645
gene id: 1769779:AUP74_RS15645
uniprot id: A0A1C9WBL4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS10115
gene id: 1769779:AUP74_RS10115
uniprot id: A0A1C9W8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1769779:AUP74 RS06800
gene id: 1769779:AUP74_RS06800
uniprot id: A0A1C9W6Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1769779:AUP74 RS03980
gene id: 1769779:AUP74_RS03980
uniprot id: A0A1C9W539
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1769779:AUP74 RS16355
gene id: 1769779:AUP74_RS16355
uniprot id: A0A1C9WBY2
names: Similarity
messages: Belongs to the peptidase C40 family.

1769779:AUP74 RS01720
gene id: 1769779:AUP74_RS01720
uniprot id: A0A1C9W3U8
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1769779:AUP74 RS02870
gene id: 1769779:AUP74_RS02870
uniprot id: A0A1C9W4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1769779:AUP74 RS00615
gene id: 1769779:AUP74_RS00615
uniprot id: A0A1C9W387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1769779:AUP74 RS02475
gene id: 1769779:AUP74_RS02475
uniprot id: A0A1C9W478
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1769779:AUP74 RS08915
gene id: 1769779:AUP74_RS08915
uniprot id: A0A1C9W7V5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1769779:AUP74 RS13040
gene id: 1769779:AUP74_RS13040
uniprot id: A0A1C9WA39
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1769779:AUP74 RS09830
gene id: 1769779:AUP74_RS09830
uniprot id: A0A1C9W8D3
names: Similarity
messages: Belongs to the DnaA family.

1769779:AUP74 RS07785
gene id: 1769779:AUP74_RS07785
uniprot id: A0A1C9W7B0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1769779:AUP74 RS06410
gene id: 1769779:AUP74_RS06410
uniprot id: A0A1C9W6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1769779:AUP74 RS12345
gene id: 1769779:AUP74_RS12345
uniprot id: A0A1C9W9T0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1769779:AUP74 RS03760
gene id: 1769779:AUP74_RS03760
uniprot id: A0A1C9W528
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS08685
gene id: 1769779:AUP74_RS08685
uniprot id: A0A1C9W7Q4
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS04940
gene id: 1769779:AUP74_RS04940
uniprot id: A0A1C9W5M6
names: Similarity
messages: Belongs to the NAPRTase family.

1769779:AUP74 RS03230
gene id: 1769779:AUP74_RS03230
uniprot id: A0A1C9W4P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1769779:AUP74 RS05325
gene id: 1769779:AUP74_RS05325
uniprot id: A0A1C9W5W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1769779:AUP74 RS01565
gene id: 1769779:AUP74_RS01565
uniprot id: A0A1C9W3Q9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1769779:AUP74 RS09250
gene id: 1769779:AUP74_RS09250
uniprot id: A0A1C9W818
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1769779:AUP74 RS05670
gene id: 1769779:AUP74_RS05670
uniprot id: A0A1C9W631
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1769779:AUP74 RS15395
gene id: 1769779:AUP74_RS15395
uniprot id: A0A1C9WBG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap.

1769779:AUP74 RS15940
gene id: 1769779:AUP74_RS15940
uniprot id: A0A1C9WBQ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS12585
gene id: 1769779:AUP74_RS12585
uniprot id: A0A1C9WA13
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS12985
gene id: 1769779:AUP74_RS12985
uniprot id: A0A1C9WAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS05415
gene id: 1769779:AUP74_RS05415
uniprot id: A0A1C9W5X8
names: Similarity
messages: Belongs to the P(II) protein family.

1769779:AUP74 RS06075
gene id: 1769779:AUP74_RS06075
uniprot id: A0A1C9W6A9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1769779:AUP74 RS16555
gene id: 1769779:AUP74_RS16555
uniprot id: A0A1C9WC19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1769779:AUP74 RS01650
gene id: 1769779:AUP74_RS01650
uniprot id: A0A1C9W3S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS06785
gene id: 1769779:AUP74_RS06785
uniprot id: A0A1C9W6N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1769779:AUP74 RS10905
gene id: 1769779:AUP74_RS10905
uniprot id: A0A1C9W8Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1769779:AUP74 RS10335
gene id: 1769779:AUP74_RS10335
uniprot id: A0A1C9W8P6
names: Similarity
messages: Belongs to the Dps family.

1769779:AUP74 RS14075
gene id: 1769779:AUP74_RS14075
uniprot id: A0A1C9WAP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS10260
gene id: 1769779:AUP74_RS10260
uniprot id: A0A1C9W8P5
names: Similarity
messages: Belongs to the UPF0434 family.

1769779:AUP74 RS07750
gene id: 1769779:AUP74_RS07750
uniprot id: A0A1C9W766
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1769779:AUP74 RS15045
gene id: 1769779:AUP74_RS15045
uniprot id: A0A1C9WB74
names: Subcellular Location Annotation
messages: Cytoplasm

1769779:AUP74 RS14050
gene id: 1769779:AUP74_RS14050
uniprot id: A0A1C9WAP3
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1769779:AUP74 RS13960
gene id: 1769779:AUP74_RS13960
uniprot id: A0A1C9WAP0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1769779:AUP74 RS10420
gene id: 1769779:AUP74_RS10420
uniprot id: A0A1C9W8N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1769779:AUP74 RS12205
gene id: 1769779:AUP74_RS12205
uniprot id: A0A1C9W9N4
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS16710
gene id: 1769779:AUP74_RS16710
uniprot id: A0A1C9WC66
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1769779:AUP74 RS00165
gene id: 1769779:AUP74_RS00165
uniprot id: A0A1C9W2Y5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1769779:AUP74 RS14720
gene id: 1769779:AUP74_RS14720
uniprot id: A0A1C9WB01
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1769779:AUP74 RS06480
gene id: 1769779:AUP74_RS06480
uniprot id: A0A1C9W6L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1769779:AUP74 RS04475
gene id: 1769779:AUP74_RS04475
uniprot id: A0A1C9W5F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1769779:AUP74 RS03805
gene id: 1769779:AUP74_RS03805
uniprot id: A0A1C9W519
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1769779:AUP74 RS08045
gene id: 1769779:AUP74_RS08045
uniprot id: A0A1C9W7F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1769779:AUP74 RS07920
gene id: 1769779:AUP74_RS07920
uniprot id: A0A1C9W796
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS03580
gene id: 1769779:AUP74_RS03580
uniprot id: A0A1C9W4V2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1769779:AUP74 RS15690
gene id: 1769779:AUP74_RS15690
uniprot id: A0A1C9WBK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1769779:AUP74 RS12780
gene id: 1769779:AUP74_RS12780
uniprot id: A0A1C9WA08
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS12325
gene id: 1769779:AUP74_RS12325
uniprot id: A0A1C9W9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1769779:AUP74 RS04980
gene id: 1769779:AUP74_RS04980
uniprot id: A0A1C9W5N9
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS12020
gene id: 1769779:AUP74_RS12020
uniprot id: A0A1C9W9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1769779:AUP74 RS07935
gene id: 1769779:AUP74_RS07935
uniprot id: A0A1C9W7D8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1769779:AUP74 RS08925
gene id: 1769779:AUP74_RS08925
uniprot id: A0A1C9W7U4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1769779:AUP74 RS10250
gene id: 1769779:AUP74_RS10250
uniprot id: A0A1C9W8L3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1769779:AUP74 RS12925
gene id: 1769779:AUP74_RS12925
uniprot id: A0A1C9WA22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1769779:AUP74 RS04520
gene id: 1769779:AUP74_RS04520
uniprot id: A0A1C9W5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1769779:AUP74 RS04415
gene id: 1769779:AUP74_RS04415
uniprot id: A0A1C9W5G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1769779:AUP74 RS16130
gene id: 1769779:AUP74_RS16130
uniprot id: A0A1C9WBU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS07840
gene id: 1769779:AUP74_RS07840
uniprot id: A0A1C9W793
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1769779:AUP74 RS14630
gene id: 1769779:AUP74_RS14630
uniprot id: A0A1C9WAZ7
names: Similarity
messages: Belongs to the PrpD family.

1769779:AUP74 RS01780
gene id: 1769779:AUP74_RS01780
uniprot id: A0A1C9W3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS03810
gene id: 1769779:AUP74_RS03810
uniprot id: A0A1C9W543
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1769779:AUP74 RS04550
gene id: 1769779:AUP74_RS04550
uniprot id: A0A1C9W5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1769779:AUP74 RS10205
gene id: 1769779:AUP74_RS10205
uniprot id: A0A1C9W8N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1769779:AUP74 RS01630
gene id: 1769779:AUP74_RS01630
uniprot id: A0A1C9W3S8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1769779:AUP74 RS04580
gene id: 1769779:AUP74_RS04580
uniprot id: A0A1C9W5F2
names: Similarity
messages: Belongs to the DprA/Smf family.

1769779:AUP74 RS16665
gene id: 1769779:AUP74_RS16665
uniprot id: A0A1C9WC80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1769779:AUP74 RS04725
gene id: 1769779:AUP74_RS04725
uniprot id: A0A1C9W5K7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1769779:AUP74 RS09185
gene id: 1769779:AUP74_RS09185
uniprot id: A0A1C9W802
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1769779:AUP74 RS04485
gene id: 1769779:AUP74_RS04485
uniprot id: A0A1C9W5E7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1769779:AUP74 RS09180
gene id: 1769779:AUP74_RS09180
uniprot id: A0A1C9W810
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1769779:AUP74 RS07950
gene id: 1769779:AUP74_RS07950
uniprot id: A0A1C9W7A7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1769779:AUP74 RS15660
gene id: 1769779:AUP74_RS15660
uniprot id: A0A1C9WBJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1769779:AUP74 RS06910
gene id: 1769779:AUP74_RS06910
uniprot id: A0A1C9W6R1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1769779:AUP74 RS15350
gene id: 1769779:AUP74_RS15350
uniprot id: A0A1C9WBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1769779:AUP74 RS03335
gene id: 1769779:AUP74_RS03335
uniprot id: A0A1C9W4U3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1769779:AUP74 RS11055
gene id: 1769779:AUP74_RS11055
uniprot id: A0A1C9W918
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS01550
gene id: 1769779:AUP74_RS01550
uniprot id: A0A1C9W3Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1769779:AUP74 RS00105
gene id: 1769779:AUP74_RS00105
uniprot id: A0A1C9W2Y6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1769779:AUP74 RS09325
gene id: 1769779:AUP74_RS09325
uniprot id: A0A1C9W836
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1769779:AUP74 RS16825
gene id: 1769779:AUP74_RS16825
uniprot id: A0A1C9WC81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1769779:AUP74 RS05665
gene id: 1769779:AUP74_RS05665
uniprot id: A0A1C9W642
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1769779:AUP74 RS13195
gene id: 1769779:AUP74_RS13195
uniprot id: A0A1C9WA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS00270
gene id: 1769779:AUP74_RS00270
uniprot id: A0A1C9W310
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS06175
gene id: 1769779:AUP74_RS06175
uniprot id: A0A1C9W6C7
names: Similarity
messages: Belongs to the YkuD family.

1769779:AUP74 RS17490
gene id: 1769779:AUP74_RS17490
uniprot id: A0A1C9WC25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS01365
gene id: 1769779:AUP74_RS01365
uniprot id: A0A1C9W3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1769779:AUP74 RS07050
gene id: 1769779:AUP74_RS07050
uniprot id: A0A1C9W6U1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1769779:AUP74 RS12515
gene id: 1769779:AUP74_RS12515
uniprot id: A0A1C9W9U3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1769779:AUP74 RS15590
gene id: 1769779:AUP74_RS15590
uniprot id: A0A1C9WBJ2
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1769779:AUP74 RS02635
gene id: 1769779:AUP74_RS02635
uniprot id: A0A1C9W4B9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS12330
gene id: 1769779:AUP74_RS12330
uniprot id: A0A1C9W9P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1769779:AUP74 RS01130
gene id: 1769779:AUP74_RS01130
uniprot id: A0A1C9W3H2
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS05465
gene id: 1769779:AUP74_RS05465
uniprot id: A0A1C9W5Y8
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1769779:AUP74 RS11580
gene id: 1769779:AUP74_RS11580
uniprot id: A0A1C9W9G7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1769779:AUP74 RS06755
gene id: 1769779:AUP74_RS06755
uniprot id: A0A1C9W6N5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS15595
gene id: 1769779:AUP74_RS15595
uniprot id: A0A1C9WBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1769779:AUP74 RS01805
gene id: 1769779:AUP74_RS01805
uniprot id: A0A1C9W3Y8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1769779:AUP74 RS15665
gene id: 1769779:AUP74_RS15665
uniprot id: A0A1C9WBI8
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1769779:AUP74 RS09790
gene id: 1769779:AUP74_RS09790
uniprot id: A0A1C9W8C4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1769779:AUP74 RS11710
gene id: 1769779:AUP74_RS11710
uniprot id: A0A1C9W9D0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1769779:AUP74 RS05805
gene id: 1769779:AUP74_RS05805
uniprot id: A0A1C9W650
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS11185
gene id: 1769779:AUP74_RS11185
uniprot id: A0A1C9W927
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1769779:AUP74 RS02735
gene id: 1769779:AUP74_RS02735
uniprot id: A0A1C9W4E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS08230
gene id: 1769779:AUP74_RS08230
uniprot id: A0A1C9W7G3
names: Similarity
messages: Belongs to the Gfa family.

1769779:AUP74 RS05855
gene id: 1769779:AUP74_RS05855
uniprot id: A0A1C9W656
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1769779:AUP74 RS15530
gene id: 1769779:AUP74_RS15530
uniprot id: A0A1C9WBG4
names: Similarity
messages: Belongs to the threonine synthase family.

1769779:AUP74 RS11565
gene id: 1769779:AUP74_RS11565
uniprot id: A0A1C9W9C5
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1769779:AUP74 RS15525
gene id: 1769779:AUP74_RS15525
uniprot id: A0A1C9WBH5
names: Similarity
messages: Belongs to the RecJ family.

1769779:AUP74 RS00020
gene id: 1769779:AUP74_RS00020
uniprot id: A0A1C9W2V8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1769779:AUP74 RS09030
gene id: 1769779:AUP74_RS09030
uniprot id: A0A1C9W7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS13280
gene id: 1769779:AUP74_RS13280
uniprot id: A0A1C9WAA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS09255
gene id: 1769779:AUP74_RS09255
uniprot id: A0A1C9W830
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1769779:AUP74 RS12350
gene id: 1769779:AUP74_RS12350
uniprot id: A0A1C9W9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS01785
gene id: 1769779:AUP74_RS01785
uniprot id: A0A1C9W3W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1769779:AUP74 RS10165
gene id: 1769779:AUP74_RS10165
uniprot id: A0A1C9W8M2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS16870
gene id: 1769779:AUP74_RS16870
uniprot id: A0A1C9WCB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1769779:AUP74 RS08365
gene id: 1769779:AUP74_RS08365
uniprot id: A0A1C9W7J9
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1769779:AUP74 RS06860
gene id: 1769779:AUP74_RS06860
uniprot id: A0A1C9W6Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1769779:AUP74 RS05780
gene id: 1769779:AUP74_RS05780
uniprot id: A0A1C9W639
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1769779:AUP74 RS00735
gene id: 1769779:AUP74_RS00735
uniprot id: A0A1C9W3A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1769779:AUP74 RS06920
gene id: 1769779:AUP74_RS06920
uniprot id: A0A1C9W6R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1769779:AUP74 RS08005
gene id: 1769779:AUP74_RS08005
uniprot id: A0A1C9W7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS13785
gene id: 1769779:AUP74_RS13785
uniprot id: A0A1C9WAN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1769779:AUP74 RS04925
gene id: 1769779:AUP74_RS04925
uniprot id: A0A1C9W5P9
names: Similarity
messages: Belongs to the peptidase U62 family.

1769779:AUP74 RS16720
gene id: 1769779:AUP74_RS16720
uniprot id: A0A1C9WC55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1769779:AUP74 RS08235
gene id: 1769779:AUP74_RS08235
uniprot id: A0A1C9W7G7
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1769779:AUP74 RS14725
gene id: 1769779:AUP74_RS14725
uniprot id: A0A1C9WB16
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1769779:AUP74 RS10355
gene id: 1769779:AUP74_RS10355
uniprot id: A0A1C9W8M9
names: Subcellular Location Annotation
messages: Cell outer membrane

1769779:AUP74 RS12835
gene id: 1769779:AUP74_RS12835
uniprot id: A0A1C9WA65
names: Subcellular Location Annotation
messages: Cytoplasm

1769779:AUP74 RS09310
gene id: 1769779:AUP74_RS09310
uniprot id: A0A1C9W849
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1769779:AUP74 RS06820
gene id: 1769779:AUP74_RS06820
uniprot id: A0A1C9W6N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1769779:AUP74 RS03650
gene id: 1769779:AUP74_RS03650
uniprot id: A0A1C9W4X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1769779:AUP74 RS16660
gene id: 1769779:AUP74_RS16660
uniprot id: A0A1C9WC64
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1769779:AUP74 RS08595
gene id: 1769779:AUP74_RS08595
uniprot id: A0A1C9W7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1769779:AUP74 RS12980
gene id: 1769779:AUP74_RS12980
uniprot id: A0A1C9WA50
names: Similarity
messages: Belongs to the glutamine synthetase family.

1769779:AUP74 RS15025
gene id: 1769779:AUP74_RS15025
uniprot id: A0A1C9WB72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1769779:AUP74 RS12710
gene id: 1769779:AUP74_RS12710
uniprot id: A0A1C9W9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1769779:AUP74 RS15410
gene id: 1769779:AUP74_RS15410
uniprot id: A0A1C9WBD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1769779:AUP74 RS13690
gene id: 1769779:AUP74_RS13690
uniprot id: A0A1C9WAG2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS09370
gene id: 1769779:AUP74_RS09370
uniprot id: A0A1C9W877
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1769779:AUP74 RS04500
gene id: 1769779:AUP74_RS04500
uniprot id: A0A1C9W5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS02575
gene id: 1769779:AUP74_RS02575
uniprot id: A0A1C9W4A9
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS11845
gene id: 1769779:AUP74_RS11845
uniprot id: A0A1C9W9F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1769779:AUP74 RS05840
gene id: 1769779:AUP74_RS05840
uniprot id: A0A1C9W674
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1769779:AUP74 RS04410
gene id: 1769779:AUP74_RS04410
uniprot id: A0A1C9W5D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1769779:AUP74 RS00180
gene id: 1769779:AUP74_RS00180
uniprot id: A0A1C9W2Z0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1769779:AUP74 RS09240
gene id: 1769779:AUP74_RS09240
uniprot id: A0A1C9W807
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1769779:AUP74 RS16835
gene id: 1769779:AUP74_RS16835
uniprot id: A0A1C9WC89
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS02520
gene id: 1769779:AUP74_RS02520
uniprot id: A0A1C9W4A7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS10965
gene id: 1769779:AUP74_RS10965
uniprot id: A0A1C9W912
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1769779:AUP74 RS10215
gene id: 1769779:AUP74_RS10215
uniprot id: A0A1C9W8P2
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS10085
gene id: 1769779:AUP74_RS10085
uniprot id: A0A1C9W8I9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1769779:AUP74 RS04205
gene id: 1769779:AUP74_RS04205
uniprot id: A0A1C9W596
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1769779:AUP74 RS05790
gene id: 1769779:AUP74_RS05790
uniprot id: A0A1C9W663
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1769779:AUP74 RS15680
gene id: 1769779:AUP74_RS15680
uniprot id: A0A1C9WBJ0
names: Similarity
messages: Belongs to the ArsC family.

1769779:AUP74 RS02135
gene id: 1769779:AUP74_RS02135
uniprot id: A0A1C9W420
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1769779:AUP74 RS00795
gene id: 1769779:AUP74_RS00795
uniprot id: A0A1C9W3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1769779:AUP74 RS04420
gene id: 1769779:AUP74_RS04420
uniprot id: A0A1C9W5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1769779:AUP74 RS07980
gene id: 1769779:AUP74_RS07980
uniprot id: A0A1C9W7C2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1769779:AUP74 RS08520
gene id: 1769779:AUP74_RS08520
uniprot id: A0A1C9W7P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1769779:AUP74 RS16585
gene id: 1769779:AUP74_RS16585
uniprot id: A0A1C9WC22
names: Similarity
messages: Belongs to the citrate synthase family.

1769779:AUP74 RS12760
gene id: 1769779:AUP74_RS12760
uniprot id: A0A1C9W9Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS14355
gene id: 1769779:AUP74_RS14355
uniprot id: A0A1C9WAU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS04090
gene id: 1769779:AUP74_RS04090
uniprot id: A0A1C9W552
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1769779:AUP74 RS04340
gene id: 1769779:AUP74_RS04340
uniprot id: A0A1C9W5B7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1769779:AUP74 RS07665
gene id: 1769779:AUP74_RS07665
uniprot id: A0A1C9W748
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS08805
gene id: 1769779:AUP74_RS08805
uniprot id: A0A1C9W7T2
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS00260
gene id: 1769779:AUP74_RS00260
uniprot id: A0A1C9W318
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1769779:AUP74 RS04010
gene id: 1769779:AUP74_RS04010
uniprot id: A0A1C9W590
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1769779:AUP74 RS00830
gene id: 1769779:AUP74_RS00830
uniprot id: A0A1C9W3C4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1769779:AUP74 RS10985
gene id: 1769779:AUP74_RS10985
uniprot id: A0A1C9W8Z0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1769779:AUP74 RS05235
gene id: 1769779:AUP74_RS05235
uniprot id: A0A1C9W5U4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1769779:AUP74 RS01080
gene id: 1769779:AUP74_RS01080
uniprot id: A0A1C9W3G3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS02640
gene id: 1769779:AUP74_RS02640
uniprot id: A0A1C9W4D6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS16565
gene id: 1769779:AUP74_RS16565
uniprot id: A0A1C9WC52
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1769779:AUP74 RS02255
gene id: 1769779:AUP74_RS02255
uniprot id: A0A1C9W455
names: Similarity
messages: Belongs to the GSP E family.

1769779:AUP74 RS11925
gene id: 1769779:AUP74_RS11925
uniprot id: A0A1C9W9G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1769779:AUP74 RS07080
gene id: 1769779:AUP74_RS07080
uniprot id: A0A1C9W6W6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1769779:AUP74 RS01515
gene id: 1769779:AUP74_RS01515
uniprot id: A0A1C9W3P6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1769779:AUP74 RS06525
gene id: 1769779:AUP74_RS06525
uniprot id: A0A1C9W6L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1769779:AUP74 RS11310
gene id: 1769779:AUP74_RS11310
uniprot id: A0A1C9W978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1769779:AUP74 RS06760
gene id: 1769779:AUP74_RS06760
uniprot id: A0A1C9W6N1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1769779:AUP74 RS06310
gene id: 1769779:AUP74_RS06310
uniprot id: A0A1C9W6F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1769779:AUP74 RS13260
gene id: 1769779:AUP74_RS13260
uniprot id: A0A1C9WA89
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1769779:AUP74 RS06405
gene id: 1769779:AUP74_RS06405
uniprot id: A0A1C9W6G7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1769779:AUP74 RS14905
gene id: 1769779:AUP74_RS14905
uniprot id: A0A1C9WB44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1769779:AUP74 RS07035
gene id: 1769779:AUP74_RS07035
uniprot id: A0A1C9W6U9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1769779:AUP74 RS03930
gene id: 1769779:AUP74_RS03930
uniprot id: A0A1C9W530
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1769779:AUP74 RS05490
gene id: 1769779:AUP74_RS05490
uniprot id: A0A1C9W5Y9
names: Similarity
messages: Belongs to the GSP E family.

1769779:AUP74 RS00150
gene id: 1769779:AUP74_RS00150
uniprot id: A0A1C9W2Y1
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS16630
gene id: 1769779:AUP74_RS16630
uniprot id: A0A1C9WC45
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS09985
gene id: 1769779:AUP74_RS09985
uniprot id: A0A1C9W8K3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1769779:AUP74 RS06810
gene id: 1769779:AUP74_RS06810
uniprot id: A0A1C9W6P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1769779:AUP74 RS04880
gene id: 1769779:AUP74_RS04880
uniprot id: A0A1C9W5L5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS12055
gene id: 1769779:AUP74_RS12055
uniprot id: A0A1C9W9R7
names: Similarity
messages: Belongs to the citrate synthase family.

1769779:AUP74 RS08665
gene id: 1769779:AUP74_RS08665
uniprot id: A0A1C9W7S6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1769779:AUP74 RS12440
gene id: 1769779:AUP74_RS12440
uniprot id: A0A1C9W9S8
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS05755
gene id: 1769779:AUP74_RS05755
uniprot id: A0A1C9W643
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1769779:AUP74 RS15300
gene id: 1769779:AUP74_RS15300
uniprot id: A0A1C9WBC3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS09340
gene id: 1769779:AUP74_RS09340
uniprot id: A0A1C9W831
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS11330
gene id: 1769779:AUP74_RS11330
uniprot id: A0A1C9W952
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1769779:AUP74 RS14970
gene id: 1769779:AUP74_RS14970
uniprot id: A0A1C9WB52
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS06890
gene id: 1769779:AUP74_RS06890
uniprot id: A0A1C9W6T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1769779:AUP74 RS12390
gene id: 1769779:AUP74_RS12390
uniprot id: A0A1C9W9R8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1769779:AUP74 RS12890
gene id: 1769779:AUP74_RS12890
uniprot id: A0A1C9WA10
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS14705
gene id: 1769779:AUP74_RS14705
uniprot id: A0A1C9WB04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1769779:AUP74 RS07310
gene id: 1769779:AUP74_RS07310
uniprot id: A0A1C9W6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1769779:AUP74 RS09225
gene id: 1769779:AUP74_RS09225
uniprot id: A0A1C9W820
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS10150
gene id: 1769779:AUP74_RS10150
uniprot id: A0A1C9W8J2
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1769779:AUP74 RS15355
gene id: 1769779:AUP74_RS15355
uniprot id: A0A1C9WBD5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1769779:AUP74 RS15865
gene id: 1769779:AUP74_RS15865
uniprot id: A0A1C9WBN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1769779:AUP74 RS12365
gene id: 1769779:AUP74_RS12365
uniprot id: A0A1C9W9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1769779:AUP74 RS01200
gene id: 1769779:AUP74_RS01200
uniprot id: A0A1C9W3I2
names: Similarity
messages: Belongs to the GbsR family.

1769779:AUP74 RS03195
gene id: 1769779:AUP74_RS03195
uniprot id: A0A1C9W4P3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1769779:AUP74 RS15495
gene id: 1769779:AUP74_RS15495
uniprot id: A0A1C9WBI6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS13815
gene id: 1769779:AUP74_RS13815
uniprot id: A0A1C9WAK5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1769779:AUP74 RS03540
gene id: 1769779:AUP74_RS03540
uniprot id: A0A1C9W4X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1769779:AUP74 RS16550
gene id: 1769779:AUP74_RS16550
uniprot id: A0A1C9WC20
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1769779:AUP74 RS14030
gene id: 1769779:AUP74_RS14030
uniprot id: A0A1C9WAQ3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1769779:AUP74 RS15800
gene id: 1769779:AUP74_RS15800
uniprot id: A0A1C9WBM6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1769779:AUP74 RS08125
gene id: 1769779:AUP74_RS08125
uniprot id: A0A1C9W7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1769779:AUP74 RS07495
gene id: 1769779:AUP74_RS07495
uniprot id: A0A1C9W728
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1769779:AUP74 RS06515
gene id: 1769779:AUP74_RS06515
uniprot id: A0A1C9W6K5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1769779:AUP74 RS05470
gene id: 1769779:AUP74_RS05470
uniprot id: A0A1C9W601
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1769779:AUP74 RS13515
gene id: 1769779:AUP74_RS13515
uniprot id: A0A1C9WAD2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1769779:AUP74 RS15655
gene id: 1769779:AUP74_RS15655
uniprot id: A0A1C9WBK2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1769779:AUP74 RS07325
gene id: 1769779:AUP74_RS07325
uniprot id: A0A1C9W6Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1769779:AUP74 RS07075
gene id: 1769779:AUP74_RS07075
uniprot id: A0A1C9W6V9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1769779:AUP74 RS02150
gene id: 1769779:AUP74_RS02150
uniprot id: A0A1C9W462
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1769779:AUP74 RS04460
gene id: 1769779:AUP74_RS04460
uniprot id: A0A1C9W5H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1769779:AUP74 RS01315
gene id: 1769779:AUP74_RS01315
uniprot id: A0A1C9W3K5
names: Similarity
messages: Belongs to the Gfa family.

1769779:AUP74 RS02435
gene id: 1769779:AUP74_RS02435
uniprot id: A0A1C9W473
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1769779:AUP74 RS15825
gene id: 1769779:AUP74_RS15825
uniprot id: A0A1C9WBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS10360
gene id: 1769779:AUP74_RS10360
uniprot id: A0A1C9W8S9
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS04730
gene id: 1769779:AUP74_RS04730
uniprot id: A0A1C9W5I8
names: Similarity
messages: Belongs to the SCO1/2 family.

1769779:AUP74 RS10625
gene id: 1769779:AUP74_RS10625
uniprot id: A0A1C9W8U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS04190
gene id: 1769779:AUP74_RS04190
uniprot id: A0A1C9W578
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1769779:AUP74 RS00290
gene id: 1769779:AUP74_RS00290
uniprot id: A0A1C9W301
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1769779:AUP74 RS09585
gene id: 1769779:AUP74_RS09585
uniprot id: A0A1C9W885
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1769779:AUP74 RS09440
gene id: 1769779:AUP74_RS09440
uniprot id: A0A1C9W875
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1769779:AUP74 RS10340
gene id: 1769779:AUP74_RS10340
uniprot id: A0A1C9W8P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS12735
gene id: 1769779:AUP74_RS12735
uniprot id: A0A1C9WA44
names: Similarity
messages: Belongs to the pirin family.

1769779:AUP74 RS13530
gene id: 1769779:AUP74_RS13530
uniprot id: A0A1C9WAF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS08275
gene id: 1769779:AUP74_RS08275
uniprot id: A0A1C9W7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1769779:AUP74 RS04825
gene id: 1769779:AUP74_RS04825
uniprot id: A0A1C9W5M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1769779:AUP74 RS09845
gene id: 1769779:AUP74_RS09845
uniprot id: A0A1C9W8D6
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1769779:AUP74 RS11920
gene id: 1769779:AUP74_RS11920
uniprot id: A0A1C9W9G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1769779:AUP74 RS12070
gene id: 1769779:AUP74_RS12070
uniprot id: A0A1C9W9P9
names: Similarity
messages: Belongs to the PrpF family.

1769779:AUP74 RS15390
gene id: 1769779:AUP74_RS15390
uniprot id: A0A1C9WBD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1769779:AUP74 RS13200
gene id: 1769779:AUP74_RS13200
uniprot id: A0A1C9WA77
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1769779:AUP74 RS10970
gene id: 1769779:AUP74_RS10970
uniprot id: A0A1C9W903
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS02245
gene id: 1769779:AUP74_RS02245
uniprot id: A0A1C9W448
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS10745
gene id: 1769779:AUP74_RS10745
uniprot id: A0A1C9W8Z7
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1769779:AUP74 RS06370
gene id: 1769779:AUP74_RS06370
uniprot id: A0A1C9W6G6
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1769779:AUP74 RS08675
gene id: 1769779:AUP74_RS08675
uniprot id: A0A1C9W7S1
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1769779:AUP74 RS06340
gene id: 1769779:AUP74_RS06340
uniprot id: A0A1C9W6I0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1769779:AUP74 RS03615
gene id: 1769779:AUP74_RS03615
uniprot id: A0A1C9W4Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1769779:AUP74 RS16670
gene id: 1769779:AUP74_RS16670
uniprot id: A0A1C9WC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS05505
gene id: 1769779:AUP74_RS05505
uniprot id: A0A1C9W603
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1769779:AUP74 RS15065
gene id: 1769779:AUP74_RS15065
uniprot id: A0A1C9WB79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1769779:AUP74 RS06990
gene id: 1769779:AUP74_RS06990
uniprot id: A0A1C9W6V2
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS09405
gene id: 1769779:AUP74_RS09405
uniprot id: A0A1C9W848
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1769779:AUP74 RS01410
gene id: 1769779:AUP74_RS01410
uniprot id: A0A1C9W3P9
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1769779:AUP74 RS07010
gene id: 1769779:AUP74_RS07010
uniprot id: A0A1C9W6T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1769779:AUP74 RS06460
gene id: 1769779:AUP74_RS06460
uniprot id: A0A1C9W6H8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS06845
gene id: 1769779:AUP74_RS06845
uniprot id: A0A1C9W6P7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1769779:AUP74 RS00430
gene id: 1769779:AUP74_RS00430
uniprot id: A0A1C9W336
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS10795
gene id: 1769779:AUP74_RS10795
uniprot id: A0A1C9W904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS11070
gene id: 1769779:AUP74_RS11070
uniprot id: A0A1C9W931
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1769779:AUP74 RS16150
gene id: 1769779:AUP74_RS16150
uniprot id: A0A1C9WBT4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1769779:AUP74 RS13850
gene id: 1769779:AUP74_RS13850
uniprot id: A0A1C9WAK8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1769779:AUP74 RS00625
gene id: 1769779:AUP74_RS00625
uniprot id: A0A1C9W381
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1769779:AUP74 RS15560
gene id: 1769779:AUP74_RS15560
uniprot id: A0A1C9WBH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1769779:AUP74 RS13180
gene id: 1769779:AUP74_RS13180
uniprot id: A0A1C9WA91
names: Similarity
messages: Belongs to the UPF0047 family.

1769779:AUP74 RS11940
gene id: 1769779:AUP74_RS11940
uniprot id: A0A1C9W9I4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1769779:AUP74 RS04570
gene id: 1769779:AUP74_RS04570
uniprot id: A0A1C9W5G9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1769779:AUP74 RS09045
gene id: 1769779:AUP74_RS09045
uniprot id: A0A1C9W7W9
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS09330
gene id: 1769779:AUP74_RS09330
uniprot id: A0A1C9W832
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1769779:AUP74 RS06985
gene id: 1769779:AUP74_RS06985
uniprot id: A0A1C9W6T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1769779:AUP74 RS10645
gene id: 1769779:AUP74_RS10645
uniprot id: A0A1C9W8T6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1769779:AUP74 RS12605
gene id: 1769779:AUP74_RS12605
uniprot id: A0A1C9W9V5
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1769779:AUP74 RS06445
gene id: 1769779:AUP74_RS06445
uniprot id: A0A1C9W6I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1769779:AUP74 RS00770
gene id: 1769779:AUP74_RS00770
uniprot id: A0A1C9W3B6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1769779:AUP74 RS02460
gene id: 1769779:AUP74_RS02460
uniprot id: A0A1C9W484
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1769779:AUP74 RS15810
gene id: 1769779:AUP74_RS15810
uniprot id: A0A1C9WBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1769779:AUP74 RS05810
gene id: 1769779:AUP74_RS05810
uniprot id: A0A1C9W681
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1769779:AUP74 RS00275
gene id: 1769779:AUP74_RS00275
uniprot id: A0A1C9W306
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1769779:AUP74 RS11210
gene id: 1769779:AUP74_RS11210
uniprot id: A0A1C9W950
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1769779:AUP74 RS00650
gene id: 1769779:AUP74_RS00650
uniprot id: A0A1C9W367
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS16480
gene id: 1769779:AUP74_RS16480
uniprot id: A0A1C9WC09
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS14945
gene id: 1769779:AUP74_RS14945
uniprot id: A0A1C9WB49
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS15675
gene id: 1769779:AUP74_RS15675
uniprot id: A0A1C9WBK1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS09455
gene id: 1769779:AUP74_RS09455
uniprot id: A0A1C9W859
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1769779:AUP74 RS02400
gene id: 1769779:AUP74_RS02400
uniprot id: A0A1C9W498
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1769779:AUP74 RS15305
gene id: 1769779:AUP74_RS15305
uniprot id: A0A1C9WBC2
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1769779:AUP74 RS01190
gene id: 1769779:AUP74_RS01190
uniprot id: A0A1C9W3J6
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS16540
gene id: 1769779:AUP74_RS16540
uniprot id: A0A1C9WC08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1769779:AUP74 RS09270
gene id: 1769779:AUP74_RS09270
uniprot id: A0A1C9W852
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

1769779:AUP74 RS04660
gene id: 1769779:AUP74_RS04660
uniprot id: A0A1C9W5L1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1769779:AUP74 RS13480
gene id: 1769779:AUP74_RS13480
uniprot id: A0A1C9WAE0
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS07220
gene id: 1769779:AUP74_RS07220
uniprot id: A0A1C9W6Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1769779:AUP74 RS07910
gene id: 1769779:AUP74_RS07910
uniprot id: A0A1C9W7A8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1769779:AUP74 RS02975
gene id: 1769779:AUP74_RS02975
uniprot id: A0A1C9W4K9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1769779:AUP74 RS09335
gene id: 1769779:AUP74_RS09335
uniprot id: A0A1C9W855
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1769779:AUP74 RS08305
gene id: 1769779:AUP74_RS08305
uniprot id: A0A1C9W7K3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS11785
gene id: 1769779:AUP74_RS11785
uniprot id: A0A1C9W9E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1769779:AUP74 RS08210
gene id: 1769779:AUP74_RS08210
uniprot id: A0A1C9W7I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1769779:AUP74 RS15570
gene id: 1769779:AUP74_RS15570
uniprot id: A0A1C9WBH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1769779:AUP74 RS06610
gene id: 1769779:AUP74_RS06610
uniprot id: A0A1C9W6M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1769779:AUP74 RS07925
gene id: 1769779:AUP74_RS07925
uniprot id: A0A1C9W7A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1769779:AUP74 RS06555
gene id: 1769779:AUP74_RS06555
uniprot id: A0A1C9W6J7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1769779:AUP74 RS04820
gene id: 1769779:AUP74_RS04820
uniprot id: A0A1C9W5L0
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1769779:AUP74 RS16055
gene id: 1769779:AUP74_RS16055
uniprot id: A0A1C9WBR2
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS08065
gene id: 1769779:AUP74_RS08065
uniprot id: A0A1C9W7E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1769779:AUP74 RS12470
gene id: 1769779:AUP74_RS12470
uniprot id: A0A1C9W9T7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1769779:AUP74 RS16125
gene id: 1769779:AUP74_RS16125
uniprot id: A0A1C9WBT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1769779:AUP74 RS04625
gene id: 1769779:AUP74_RS04625
uniprot id: A0A1C9W5J5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS10960
gene id: 1769779:AUP74_RS10960
uniprot id: A0A1C9W909
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1769779:AUP74 RS00155
gene id: 1769779:AUP74_RS00155
uniprot id: A0A1C9W2Z4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1769779:AUP74 RS08080
gene id: 1769779:AUP74_RS08080
uniprot id: A0A1C9W7D4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1769779:AUP74 RS10325
gene id: 1769779:AUP74_RS10325
uniprot id: A0A1C9W8M7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1769779:AUP74 RS11795
gene id: 1769779:AUP74_RS11795
uniprot id: A0A1C9W9F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1769779:AUP74 RS08350
gene id: 1769779:AUP74_RS08350
uniprot id: A0A1C9W7J0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1769779:AUP74 RS04065
gene id: 1769779:AUP74_RS04065
uniprot id: A0A1C9W560
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1769779:AUP74 RS08705
gene id: 1769779:AUP74_RS08705
uniprot id: A0A1C9W7Q5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1769779:AUP74 RS00870
gene id: 1769779:AUP74_RS00870
uniprot id: A0A1C9W3C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1769779:AUP74 RS09120
gene id: 1769779:AUP74_RS09120
uniprot id: A0A1C9W7Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1769779:AUP74 RS12815
gene id: 1769779:AUP74_RS12815
uniprot id: A0A1C9W9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1769779:AUP74 RS08340
gene id: 1769779:AUP74_RS08340
uniprot id: A0A1C9W7I7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1769779:AUP74 RS07090
gene id: 1769779:AUP74_RS07090
uniprot id: A0A1C9W6X2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1769779:AUP74 RS01735
gene id: 1769779:AUP74_RS01735
uniprot id: A0A1C9W3V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1769779:AUP74 RS09445
gene id: 1769779:AUP74_RS09445
uniprot id: A0A1C9W857
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1769779:AUP74 RS15585
gene id: 1769779:AUP74_RS15585
uniprot id: A0A1C9WBH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1769779:AUP74 RS06440
gene id: 1769779:AUP74_RS06440
uniprot id: A0A1C9W6K3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1769779:AUP74 RS08790
gene id: 1769779:AUP74_RS08790
uniprot id: A0A1C9W7S5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1769779:AUP74 RS09785
gene id: 1769779:AUP74_RS09785
uniprot id: A0A1C9W8C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1769779:AUP74 RS06650
gene id: 1769779:AUP74_RS06650
uniprot id: A0A1C9W6M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS10380
gene id: 1769779:AUP74_RS10380
uniprot id: A0A1C9W8N2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS03670
gene id: 1769779:AUP74_RS03670
uniprot id: A0A1C9W515
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1769779:AUP74 RS03180
gene id: 1769779:AUP74_RS03180
uniprot id: A0A1C9W4P0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1769779:AUP74 RS03690
gene id: 1769779:AUP74_RS03690
uniprot id: A0A1C9W514
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS03215
gene id: 1769779:AUP74_RS03215
uniprot id: A0A1C9W4P1
names: Similarity
messages: Belongs to the peptidase S41A family.

1769779:AUP74 RS03960
gene id: 1769779:AUP74_RS03960
uniprot id: A0A1C9W581
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1769779:AUP74 RS07800
gene id: 1769779:AUP74_RS07800
uniprot id: A0A1C9W776
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1769779:AUP74 RS02885
gene id: 1769779:AUP74_RS02885
uniprot id: A0A1C9W4G8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1769779:AUP74 RS07030
gene id: 1769779:AUP74_RS07030
uniprot id: A0A1C9W6V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1769779:AUP74 RS11885
gene id: 1769779:AUP74_RS11885
uniprot id: A0A1C9W9G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1769779:AUP74 RS00075
gene id: 1769779:AUP74_RS00075
uniprot id: A0A1C9W2W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1769779:AUP74 RS03820
gene id: 1769779:AUP74_RS03820
uniprot id: A0A1C9W517
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1769779:AUP74 RS11830
gene id: 1769779:AUP74_RS11830
uniprot id: A0A1C9W9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1769779:AUP74 RS11245
gene id: 1769779:AUP74_RS11245
uniprot id: A0A1C9W936
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1769779:AUP74 RS08725
gene id: 1769779:AUP74_RS08725
uniprot id: A0A1C9W7V0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1769779:AUP74 RS08090
gene id: 1769779:AUP74_RS08090
uniprot id: A0A1C9W7E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1769779:AUP74 RS10410
gene id: 1769779:AUP74_RS10410
uniprot id: A0A1C9W8P0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

1769779:AUP74 RS08975
gene id: 1769779:AUP74_RS08975
uniprot id: A0A1C9W7Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS15080
gene id: 1769779:AUP74_RS15080
uniprot id: A0A1C9WB80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS05420
gene id: 1769779:AUP74_RS05420
uniprot id: A0A1C9W5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1769779:AUP74 RS14500
gene id: 1769779:AUP74_RS14500
uniprot id: A0A1C9WAX5
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS12050
gene id: 1769779:AUP74_RS12050
uniprot id: A0A1C9W9K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1769779:AUP74 RS16080
gene id: 1769779:AUP74_RS16080
uniprot id: A0A1C9WBT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1769779:AUP74 RS05845
gene id: 1769779:AUP74_RS05845
uniprot id: A0A1C9W669
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1769779:AUP74 RS00925
gene id: 1769779:AUP74_RS00925
uniprot id: A0A1C9W3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1769779:AUP74 RS08355
gene id: 1769779:AUP74_RS08355
uniprot id: A0A1C9W7K8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1769779:AUP74 RS00765
gene id: 1769779:AUP74_RS00765
uniprot id: A0A1C9W399
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1769779:AUP74 RS15545
gene id: 1769779:AUP74_RS15545
uniprot id: A0A1C9WBJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1769779:AUP74 RS11915
gene id: 1769779:AUP74_RS11915
uniprot id: A0A1C9W9M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1769779:AUP74 RS01095
gene id: 1769779:AUP74_RS01095
uniprot id: A0A1C9W3H3
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS04590
gene id: 1769779:AUP74_RS04590
uniprot id: A0A1C9W5G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1769779:AUP74 RS06465
gene id: 1769779:AUP74_RS06465
uniprot id: A0A1C9W6J8
names: Similarity
messages: Belongs to the TrpC family.

1769779:AUP74 RS16775
gene id: 1769779:AUP74_RS16775
uniprot id: A0A1C9WC53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1769779:AUP74 RS08215
gene id: 1769779:AUP74_RS08215
uniprot id: A0A1C9W7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1769779:AUP74 RS04060
gene id: 1769779:AUP74_RS04060
uniprot id: A0A1C9W5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1769779:AUP74 RS06520
gene id: 1769779:AUP74_RS06520
uniprot id: A0A1C9W6J6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1769779:AUP74 RS10900
gene id: 1769779:AUP74_RS10900
uniprot id: A0A1C9W8Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS15815
gene id: 1769779:AUP74_RS15815
uniprot id: A0A1C9WBM9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1769779:AUP74 RS16210
gene id: 1769779:AUP74_RS16210
uniprot id: A0A1C9WBV6
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1769779:AUP74 RS12305
gene id: 1769779:AUP74_RS12305
uniprot id: A0A1C9W9N7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1769779:AUP74 RS09690
gene id: 1769779:AUP74_RS09690
uniprot id: A0A1C9W8A2
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS12525
gene id: 1769779:AUP74_RS12525
uniprot id: A0A1C9W9U5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1769779:AUP74 RS13080
gene id: 1769779:AUP74_RS13080
uniprot id: A0A1C9WA71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1769779:AUP74 RS00695
gene id: 1769779:AUP74_RS00695
uniprot id: A0A1C9W3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS14130
gene id: 1769779:AUP74_RS14130
uniprot id: A0A1C9WAT2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1769779:AUP74 RS00015
gene id: 1769779:AUP74_RS00015
uniprot id: A0A1C9W2W7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1769779:AUP74 RS12955
gene id: 1769779:AUP74_RS12955
uniprot id: A0A1C9WA23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS03770
gene id: 1769779:AUP74_RS03770
uniprot id: A0A1C9W510
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS14805
gene id: 1769779:AUP74_RS14805
uniprot id: A0A1C9WB18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1769779:AUP74 RS08455
gene id: 1769779:AUP74_RS08455
uniprot id: A0A1C9W7M3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1769779:AUP74 RS11250
gene id: 1769779:AUP74_RS11250
uniprot id: A0A1C9W938
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1769779:AUP74 RS03955
gene id: 1769779:AUP74_RS03955
uniprot id: A0A1C9W553
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1769779:AUP74 RS15325
gene id: 1769779:AUP74_RS15325
uniprot id: A0A1C9WBD4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1769779:AUP74 RS14350
gene id: 1769779:AUP74_RS14350
uniprot id: A0A1C9WAV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS02615
gene id: 1769779:AUP74_RS02615
uniprot id: A0A1C9W4C1
names: Similarity
messages: Belongs to the peptidase S58 family.

1769779:AUP74 RS16865
gene id: 1769779:AUP74_RS16865
uniprot id: A0A1C9WC87
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1769779:AUP74 RS07475
gene id: 1769779:AUP74_RS07475
uniprot id: A0A1C9W718
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1769779:AUP74 RS11865
gene id: 1769779:AUP74_RS11865
uniprot id: A0A1C9W9L3
names: Similarity
messages: Belongs to the LOG family.

1769779:AUP74 RS11190
gene id: 1769779:AUP74_RS11190
uniprot id: A0A1C9W929
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1769779:AUP74 RS05140
gene id: 1769779:AUP74_RS05140
uniprot id: A0A1C9W5V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1769779:AUP74 RS12940
gene id: 1769779:AUP74_RS12940
uniprot id: A0A1C9WA17
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1769779:AUP74 RS11400
gene id: 1769779:AUP74_RS11400
uniprot id: A0A1C9W974
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1769779:AUP74 RS01540
gene id: 1769779:AUP74_RS01540
uniprot id: A0A1C9W3Q0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1769779:AUP74 RS01085
gene id: 1769779:AUP74_RS01085
uniprot id: A0A1C9W3G6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS16075
gene id: 1769779:AUP74_RS16075
uniprot id: A0A1C9WBS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1769779:AUP74 RS11275
gene id: 1769779:AUP74_RS11275
uniprot id: A0A1C9W988
names: Similarity
messages: Belongs to the peptidase S49 family.

1769779:AUP74 RS12400
gene id: 1769779:AUP74_RS12400
uniprot id: A0A1C9W9R2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1769779:AUP74 RS14795
gene id: 1769779:AUP74_RS14795
uniprot id: A0A1C9WB23
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1769779:AUP74 RS11450
gene id: 1769779:AUP74_RS11450
uniprot id: A0A1C9W983
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1769779:AUP74 RS01275
gene id: 1769779:AUP74_RS01275
uniprot id: A0A1C9W3K6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS03865
gene id: 1769779:AUP74_RS03865
uniprot id: A0A1C9W516
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1769779:AUP74 RS08330
gene id: 1769779:AUP74_RS08330
uniprot id: A0A1C9W7J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1769779:AUP74 RS09775
gene id: 1769779:AUP74_RS09775
uniprot id: A0A1C9W8C3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1769779:AUP74 RS13155
gene id: 1769779:AUP74_RS13155
uniprot id: A0A1C9WA64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1769779:AUP74 RS12200
gene id: 1769779:AUP74_RS12200
uniprot id: A0A1C9W9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1769779:AUP74 RS09450
gene id: 1769779:AUP74_RS09450
uniprot id: A0A1C9W882
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1769779:AUP74 RS02850
gene id: 1769779:AUP74_RS02850
uniprot id: A0A1C9W4H5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1769779:AUP74 RS05850
gene id: 1769779:AUP74_RS05850
uniprot id: A0A1C9W675
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1769779:AUP74 RS10480
gene id: 1769779:AUP74_RS10480
uniprot id: A0A1C9W8P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1769779:AUP74 RS04935
gene id: 1769779:AUP74_RS04935
uniprot id: A0A1C9W5P1
names: Similarity
messages: Belongs to the peptidase U62 family.

1769779:AUP74 RS03950
gene id: 1769779:AUP74_RS03950
uniprot id: A0A1C9W522
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1769779:AUP74 RS07185
gene id: 1769779:AUP74_RS07185
uniprot id: A0A1C9W6X9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1769779:AUP74 RS05365
gene id: 1769779:AUP74_RS05365
uniprot id: A0A1C9W5X2
names: Similarity
messages: Belongs to the UPF0178 family.

1769779:AUP74 RS09175
gene id: 1769779:AUP74_RS09175
uniprot id: A0A1C9W839
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1769779:AUP74 RS08200
gene id: 1769779:AUP74_RS08200
uniprot id: A0A1C9W7F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1769779:AUP74 RS01325
gene id: 1769779:AUP74_RS01325
uniprot id: A0A1C9W3L5
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1769779:AUP74 RS07315
gene id: 1769779:AUP74_RS07315
uniprot id: A0A1C9W6Y6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1769779:AUP74 RS14315
gene id: 1769779:AUP74_RS14315
uniprot id: A0A1C9WAS5
names: Similarity
messages: Belongs to the PucC family.

1769779:AUP74 RS01570
gene id: 1769779:AUP74_RS01570
uniprot id: A0A1C9W3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1769779:AUP74 RS13825
gene id: 1769779:AUP74_RS13825
uniprot id: A0A1C9WAK3
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1769779:AUP74 RS09860
gene id: 1769779:AUP74_RS09860
uniprot id: A0A1C9W8F6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1769779:AUP74 RS05830
gene id: 1769779:AUP74_RS05830
uniprot id: A0A1C9W658
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1769779:AUP74 RS11645
gene id: 1769779:AUP74_RS11645
uniprot id: A0A1C9W9C1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS08195
gene id: 1769779:AUP74_RS08195
uniprot id: A0A1C9W7F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1769779:AUP74 RS14815
gene id: 1769779:AUP74_RS14815
uniprot id: A0A1C9WB19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS07535
gene id: 1769779:AUP74_RS07535
uniprot id: A0A1C9W755
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1769779:AUP74 RS12460
gene id: 1769779:AUP74_RS12460
uniprot id: A0A1C9W9R5
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS11355
gene id: 1769779:AUP74_RS11355
uniprot id: A0A1C9W969
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1769779:AUP74 RS16085
gene id: 1769779:AUP74_RS16085
uniprot id: A0A1C9WBT6
names: Similarity
messages: Belongs to the TrpF family.

1769779:AUP74 RS04120
gene id: 1769779:AUP74_RS04120
uniprot id: A0A1C9W580
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1769779:AUP74 RS05975
gene id: 1769779:AUP74_RS05975
uniprot id: A0A1C9W6C0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1769779:AUP74 RS06905
gene id: 1769779:AUP74_RS06905
uniprot id: A0A1C9W6R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1769779:AUP74 RS14980
gene id: 1769779:AUP74_RS14980
uniprot id: A0A1C9WB62
names: Similarity
messages: Belongs to the peptidase S51 family.

1769779:AUP74 RS02315
gene id: 1769779:AUP74_RS02315
uniprot id: A0A1C9W463
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1769779:AUP74 RS02195
gene id: 1769779:AUP74_RS02195
uniprot id: A0A1C9W436
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1769779:AUP74 RS08030
gene id: 1769779:AUP74_RS08030
uniprot id: A0A1C9W7C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS15760
gene id: 1769779:AUP74_RS15760
uniprot id: A0A1C9WBK9
names: Similarity
messages: Belongs to the YciI family.

1769779:AUP74 RS14810
gene id: 1769779:AUP74_RS14810
uniprot id: A0A1C9WB43
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1769779:AUP74 RS03735
gene id: 1769779:AUP74_RS03735
uniprot id: A0A1C9W4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1769779:AUP74 RS02325
gene id: 1769779:AUP74_RS02325
uniprot id: A0A1C9W458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1769779:AUP74 RS03190
gene id: 1769779:AUP74_RS03190
uniprot id: A0A1C9W4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1769779:AUP74 RS00935
gene id: 1769779:AUP74_RS00935
uniprot id: A0A1C9W3D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1769779:AUP74 RS00960
gene id: 1769779:AUP74_RS00960
uniprot id: A0A1C9W3D0
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1769779:AUP74 RS00410
gene id: 1769779:AUP74_RS00410
uniprot id: A0A1C9W352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1769779:AUP74 RS13925
gene id: 1769779:AUP74_RS13925
uniprot id: A0A1C9WAM2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1769779:AUP74 RS07190
gene id: 1769779:AUP74_RS07190
uniprot id: A0A1C9W6Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1769779:AUP74 RS04815
gene id: 1769779:AUP74_RS04815
uniprot id: A0A1C9W5L3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1769779:AUP74 RS08285
gene id: 1769779:AUP74_RS08285
uniprot id: A0A1C9W7H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1769779:AUP74 RS06010
gene id: 1769779:AUP74_RS06010
uniprot id: A0A1C9W6A3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS14635
gene id: 1769779:AUP74_RS14635
uniprot id: A0A1C9WAZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1769779:AUP74 RS06930
gene id: 1769779:AUP74_RS06930
uniprot id: A0A1C9W6U3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1769779:AUP74 RS03965
gene id: 1769779:AUP74_RS03965
uniprot id: A0A1C9W536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1769779:AUP74 RS04330
gene id: 1769779:AUP74_RS04330
uniprot id: A0A1C9W5D6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS04445
gene id: 1769779:AUP74_RS04445
uniprot id: A0A1C9W5D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1769779:AUP74 RS11220
gene id: 1769779:AUP74_RS11220
uniprot id: A0A1C9W954
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1769779:AUP74 RS15400
gene id: 1769779:AUP74_RS15400
uniprot id: A0A1C9WBF0
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1769779:AUP74 RS13420
gene id: 1769779:AUP74_RS13420
uniprot id: A0A1C9WAA5
names: Similarity
messages: Belongs to the peptidase M16 family.

1769779:AUP74 RS16230
gene id: 1769779:AUP74_RS16230
uniprot id: A0A1C9WBV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1769779:AUP74 RS08660
gene id: 1769779:AUP74_RS08660
uniprot id: A0A1C9W7Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1769779:AUP74 RS12700
gene id: 1769779:AUP74_RS12700
uniprot id: A0A1C9W9W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1769779:AUP74 RS09235
gene id: 1769779:AUP74_RS09235
uniprot id: A0A1C9W837
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1769779:AUP74 RS15640
gene id: 1769779:AUP74_RS15640
uniprot id: A0A1C9WBK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1769779:AUP74 RS02665
gene id: 1769779:AUP74_RS02665
uniprot id: A0A1C9W4C7
names: Similarity
messages: Belongs to the peptidase M1 family.

1769779:AUP74 RS04115
gene id: 1769779:AUP74_RS04115
uniprot id: A0A1C9W570
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1769779:AUP74 RS04605
gene id: 1769779:AUP74_RS04605
uniprot id: A0A1C9W5H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1769779:AUP74 RS05545
gene id: 1769779:AUP74_RS05545
uniprot id: A0A1C9W632
names: Similarity
messages: Belongs to the thioredoxin family.

1769779:AUP74 RS03520
gene id: 1769779:AUP74_RS03520
uniprot id: A0A1C9W4V3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1769779:AUP74 RS15540
gene id: 1769779:AUP74_RS15540
uniprot id: A0A1C9WBH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1769779:AUP74 RS16645
gene id: 1769779:AUP74_RS16645
uniprot id: A0A1C9WC70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1769779:AUP74 RS05510
gene id: 1769779:AUP74_RS05510
uniprot id: A0A1C9W613
names: Similarity
messages: Belongs to the YggT family.

1769779:AUP74 RS01100
gene id: 1769779:AUP74_RS01100
uniprot id: A0A1C9W3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS15860
gene id: 1769779:AUP74_RS15860
uniprot id: A0A1C9WBP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1769779:AUP74 RS08470
gene id: 1769779:AUP74_RS08470
uniprot id: A0A1C9W7N7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1769779:AUP74 RS13990
gene id: 1769779:AUP74_RS13990
uniprot id: A0A1C9WAN4
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1769779:AUP74 RS04310
gene id: 1769779:AUP74_RS04310
uniprot id: A0A1C9W5B2
names: Similarity
messages: Belongs to the pirin family.

1769779:AUP74 RS02945
gene id: 1769779:AUP74_RS02945
uniprot id: A0A1C9W4J3
names: Similarity
messages: Belongs to the peptidase S8 family.

1769779:AUP74 RS10670
gene id: 1769779:AUP74_RS10670
uniprot id: A0A1C9W8U5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1769779:AUP74 RS15600
gene id: 1769779:AUP74_RS15600
uniprot id: A0A1C9WBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1769779:AUP74 RS06830
gene id: 1769779:AUP74_RS06830
uniprot id: A0A1C9W6T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1769779:AUP74 RS03725
gene id: 1769779:AUP74_RS03725
uniprot id: A0A1C9W524
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1769779:AUP74 RS00775
gene id: 1769779:AUP74_RS00775
uniprot id: A0A1C9W3A1
names: Similarity
messages: Belongs to the universal stress protein A family.

1769779:AUP74 RS16460
gene id: 1769779:AUP74_RS16460
uniprot id: A0A1C9WC17
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS02430
gene id: 1769779:AUP74_RS02430
uniprot id: A0A1C9W4A8
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS04170
gene id: 1769779:AUP74_RS04170
uniprot id: A0A1C9W588
names: Similarity
messages: Belongs to the UPF0246 family.

1769779:AUP74 RS06945
gene id: 1769779:AUP74_RS06945
uniprot id: A0A1C9W6R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1769779:AUP74 RS04700
gene id: 1769779:AUP74_RS04700
uniprot id: A0A1C9W5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS01975
gene id: 1769779:AUP74_RS01975
uniprot id: A0A1C9W3Y6
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS11695
gene id: 1769779:AUP74_RS11695
uniprot id: A0A1C9W9D7
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1769779:AUP74 RS00720
gene id: 1769779:AUP74_RS00720
uniprot id: A0A1C9W3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS13625
gene id: 1769779:AUP74_RS13625
uniprot id: A0A1C9WAG4
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1769779:AUP74 RS15155
gene id: 1769779:AUP74_RS15155
uniprot id: A0A1C9WB91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1769779:AUP74 RS09950
gene id: 1769779:AUP74_RS09950
uniprot id: A0A1C9W8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1769779:AUP74 RS01615
gene id: 1769779:AUP74_RS01615
uniprot id: A0A1C9W3R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

1769779:AUP74 RS02235
gene id: 1769779:AUP74_RS02235
uniprot id: A0A1C9W441
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS07940
gene id: 1769779:AUP74_RS07940
uniprot id: A0A1C9W7B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1769779:AUP74 RS01165
gene id: 1769779:AUP74_RS01165
uniprot id: A0A1C9W3H9
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1769779:AUP74 RS05400
gene id: 1769779:AUP74_RS05400
uniprot id: A0A1C9W5Y7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1769779:AUP74 RS08300
gene id: 1769779:AUP74_RS08300
uniprot id: A0A1C9W7I2
names: Similarity
messages: Belongs to the peptidase S1C family.

1769779:AUP74 RS00380
gene id: 1769779:AUP74_RS00380
uniprot id: A0A1C9W325
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS12110
gene id: 1769779:AUP74_RS12110
uniprot id: A0A1C9W9L1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1769779:AUP74 RS05540
gene id: 1769779:AUP74_RS05540
uniprot id: A0A1C9W5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1769779:AUP74 RS14445
gene id: 1769779:AUP74_RS14445
uniprot id: A0A1C9WAV0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1769779:AUP74 RS02880
gene id: 1769779:AUP74_RS02880
uniprot id: A0A1C9W4H8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1769779:AUP74 RS11350
gene id: 1769779:AUP74_RS11350
uniprot id: A0A1C9W961
names: Subcellular Location Annotation
messages: Secreted

1769779:AUP74 RS03235
gene id: 1769779:AUP74_RS03235
uniprot id: A0A1C9W4R2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1769779:AUP74 RS07685
gene id: 1769779:AUP74_RS07685
uniprot id: A0A1C9W781
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1769779:AUP74 RS13655
gene id: 1769779:AUP74_RS13655
uniprot id: A0A1C9WAG6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1769779:AUP74 RS16570
gene id: 1769779:AUP74_RS16570
uniprot id: A0A1C9WC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS09020
gene id: 1769779:AUP74_RS09020
uniprot id: A0A1C9W7W6
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS02530
gene id: 1769779:AUP74_RS02530
uniprot id: A0A1C9W494
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1769779:AUP74 RS04275
gene id: 1769779:AUP74_RS04275
uniprot id: A0A1C9W5A9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1769779:AUP74 RS04540
gene id: 1769779:AUP74_RS04540
uniprot id: A0A1C9W5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1769779:AUP74 RS11935
gene id: 1769779:AUP74_RS11935
uniprot id: A0A1C9W9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1769779:AUP74 RS01255
gene id: 1769779:AUP74_RS01255
uniprot id: A0A1C9W3M1
names: Similarity
messages: Belongs to the selenium-binding protein family.

1769779:AUP74 RS09105
gene id: 1769779:AUP74_RS09105
uniprot id: A0A1C9W7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1769779:AUP74 RS12990
gene id: 1769779:AUP74_RS12990
uniprot id: A0A1C9WA30
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1769779:AUP74 RS00895
gene id: 1769779:AUP74_RS00895
uniprot id: A0A1C9W3D3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS13385
gene id: 1769779:AUP74_RS13385
uniprot id: A0A1C9WAG9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1769779:AUP74 RS11160
gene id: 1769779:AUP74_RS11160
uniprot id: A0A1C9W943
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1769779:AUP74 RS11230
gene id: 1769779:AUP74_RS11230
uniprot id: A0A1C9W933
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1769779:AUP74 RS13085
gene id: 1769779:AUP74_RS13085
uniprot id: A0A1C9WAB4
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1769779:AUP74 RS16780
gene id: 1769779:AUP74_RS16780
uniprot id: A0A1C9WC84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1769779:AUP74 RS09975
gene id: 1769779:AUP74_RS09975
uniprot id: A0A1C9W8H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1769779:AUP74 RS06710
gene id: 1769779:AUP74_RS06710
uniprot id: A0A1C9W6M8
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1769779:AUP74 RS07945
gene id: 1769779:AUP74_RS07945
uniprot id: A0A1C9W7D5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1769779:AUP74 RS01090
gene id: 1769779:AUP74_RS01090
uniprot id: A0A1C9W3H1
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS07965
gene id: 1769779:AUP74_RS07965
uniprot id: A0A1C9W7A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1769779:AUP74 RS09485
gene id: 1769779:AUP74_RS09485
uniprot id: A0A1C9W866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1769779:AUP74 RS08985
gene id: 1769779:AUP74_RS08985
uniprot id: A0A1C9W7V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1769779:AUP74 RS14450
gene id: 1769779:AUP74_RS14450
uniprot id: A0A1C9WAW8
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS16145
gene id: 1769779:AUP74_RS16145
uniprot id: A0A1C9WBW8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1769779:AUP74 RS00225
gene id: 1769779:AUP74_RS00225
uniprot id: A0A1C9W2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS07490
gene id: 1769779:AUP74_RS07490
uniprot id: A0A1C9W734
names: Similarity
messages: Belongs to the peptidase M13 family.

1769779:AUP74 RS06060
gene id: 1769779:AUP74_RS06060
uniprot id: A0A1C9W689
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1769779:AUP74 RS10075
gene id: 1769779:AUP74_RS10075
uniprot id: A0A1C9W8I4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1769779:AUP74 RS13090
gene id: 1769779:AUP74_RS13090
uniprot id: A0A1C9WA47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1769779:AUP74 RS13360
gene id: 1769779:AUP74_RS13360
uniprot id: A0A1C9WA98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1769779:AUP74 RS08130
gene id: 1769779:AUP74_RS08130
uniprot id: A0A1C9W7D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1769779:AUP74 RS06955
gene id: 1769779:AUP74_RS06955
uniprot id: A0A1C9W6S8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1769779:AUP74 RS01925
gene id: 1769779:AUP74_RS01925
uniprot id: A0A1C9W3Y4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1769779:AUP74 RS00970
gene id: 1769779:AUP74_RS00970
uniprot id: A0A1C9W3E1
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS13425
gene id: 1769779:AUP74_RS13425
uniprot id: A0A1C9WAB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS12220
gene id: 1769779:AUP74_RS12220
uniprot id: A0A1C9W9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1769779:AUP74 RS01900
gene id: 1769779:AUP74_RS01900
uniprot id: A0A1C9W3X6
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS06170
gene id: 1769779:AUP74_RS06170
uniprot id: A0A1C9W6G4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1769779:AUP74 RS05355
gene id: 1769779:AUP74_RS05355
uniprot id: A0A1C9W5X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1769779:AUP74 RS08910
gene id: 1769779:AUP74_RS08910
uniprot id: A0A1C9W7U7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1769779:AUP74 RS09580
gene id: 1769779:AUP74_RS09580
uniprot id: A0A1C9W879
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1769779:AUP74 RS05705
gene id: 1769779:AUP74_RS05705
uniprot id: A0A1C9W637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1769779:AUP74 RS09915
gene id: 1769779:AUP74_RS09915
uniprot id: A0A1C9W8F1
names: Similarity
messages: Belongs to the peptidase C69 family.

1769779:AUP74 RS01355
gene id: 1769779:AUP74_RS01355
uniprot id: A0A1C9W3P2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1769779:AUP74 RS05115
gene id: 1769779:AUP74_RS05115
uniprot id: A0A1C9W5S7
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1769779:AUP74 RS00095
gene id: 1769779:AUP74_RS00095
uniprot id: A0A1C9W2X3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1769779:AUP74 RS10750
gene id: 1769779:AUP74_RS10750
uniprot id: A0A1C9W8V6
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1769779:AUP74 RS04425
gene id: 1769779:AUP74_RS04425
uniprot id: A0A1C9W5E0
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS02190
gene id: 1769779:AUP74_RS02190
uniprot id: A0A1C9W437
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1769779:AUP74 RS08335
gene id: 1769779:AUP74_RS08335
uniprot id: A0A1C9W7I1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1769779:AUP74 RS13015
gene id: 1769779:AUP74_RS13015
uniprot id: A0A1C9WA38
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1769779:AUP74 RS13485
gene id: 1769779:AUP74_RS13485
uniprot id: A0A1C9WAI7
names: Similarity
messages: Belongs to the SUI1 family.

1769779:AUP74 RS11930
gene id: 1769779:AUP74_RS11930
uniprot id: A0A1C9W9G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1769779:AUP74 RS01580
gene id: 1769779:AUP74_RS01580
uniprot id: A0A1C9W3R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS14490
gene id: 1769779:AUP74_RS14490
uniprot id: A0A1C9WAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS02660
gene id: 1769779:AUP74_RS02660
uniprot id: A0A1C9W4C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1769779:AUP74 RS12310
gene id: 1769779:AUP74_RS12310
uniprot id: A0A1C9W9P7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1769779:AUP74 RS00080
gene id: 1769779:AUP74_RS00080
uniprot id: A0A1C9W2X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1769779:AUP74 RS15840
gene id: 1769779:AUP74_RS15840
uniprot id: A0A1C9WBN3
names: Similarity
messages: Belongs to the TPP enzyme family.

1769779:AUP74 RS09115
gene id: 1769779:AUP74_RS09115
uniprot id: A0A1C9W811
names: Similarity
messages: Belongs to the HesB/IscA family.

1769779:AUP74 RS00390
gene id: 1769779:AUP74_RS00390
uniprot id: A0A1C9W330
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1769779:AUP74 RS06715
gene id: 1769779:AUP74_RS06715
uniprot id: A0A1C9W6Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1769779:AUP74 RS00465
gene id: 1769779:AUP74_RS00465
uniprot id: A0A1C9W348
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1769779:AUP74 RS15990
gene id: 1769779:AUP74_RS15990
uniprot id: A0A1C9WBR3
names: Similarity
messages: Belongs to the WrbA family.

1769779:AUP74 RS04390
gene id: 1769779:AUP74_RS04390
uniprot id: A0A1C9W5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1769779:AUP74 RS04930
gene id: 1769779:AUP74_RS04930
uniprot id: A0A1C9W5M9
names: Similarity
messages: Belongs to the peptidase U62 family.

1769779:AUP74 RS10270
gene id: 1769779:AUP74_RS10270
uniprot id: A0A1C9W8M0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1769779:AUP74 RS15805
gene id: 1769779:AUP74_RS15805
uniprot id: A0A1C9WBM1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1769779:AUP74 RS04405
gene id: 1769779:AUP74_RS04405
uniprot id: A0A1C9W5C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1769779:AUP74 RS03260
gene id: 1769779:AUP74_RS03260
uniprot id: A0A1C9W4S8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1769779:AUP74 RS10495
gene id: 1769779:AUP74_RS10495
uniprot id: A0A1C9W8S4
names: Subcellular Location Annotation
messages: Cytoplasm

1769779:AUP74 RS03150
gene id: 1769779:AUP74_RS03150
uniprot id: A0A1C9W4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1769779:AUP74 RS00815
gene id: 1769779:AUP74_RS00815
uniprot id: A0A1C9W3B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

1769779:AUP74 RS00655
gene id: 1769779:AUP74_RS00655
uniprot id: A0A1C9W388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS06705
gene id: 1769779:AUP74_RS06705
uniprot id: A0A1C9W6R9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1769779:AUP74 RS04785
gene id: 1769779:AUP74_RS04785
uniprot id: A0A1C9W5K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1769779:AUP74 RS14150
gene id: 1769779:AUP74_RS14150
uniprot id: A0A1C9WAR5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS07350
gene id: 1769779:AUP74_RS07350
uniprot id: A0A1C9W6Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1769779:AUP74 RS05915
gene id: 1769779:AUP74_RS05915
uniprot id: A0A1C9W698
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1769779:AUP74 RS03020
gene id: 1769779:AUP74_RS03020
uniprot id: A0A1C9W4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1769779:AUP74 RS11155
gene id: 1769779:AUP74_RS11155
uniprot id: A0A1C9W945
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1769779:AUP74 RS14625
gene id: 1769779:AUP74_RS14625
uniprot id: A0A1C9WAZ5
names: Similarity
messages: Belongs to the PrpD family.

1769779:AUP74 RS15315
gene id: 1769779:AUP74_RS15315
uniprot id: A0A1C9WBC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1769779:AUP74 RS11520
gene id: 1769779:AUP74_RS11520
uniprot id: A0A1C9W9B6
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1769779:AUP74 RS01295
gene id: 1769779:AUP74_RS01295
uniprot id: A0A1C9W3K1
names: Similarity
messages: Belongs to the pirin family.

1769779:AUP74 RS16090
gene id: 1769779:AUP74_RS16090
uniprot id: A0A1C9WBS7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS12450
gene id: 1769779:AUP74_RS12450
uniprot id: A0A1C9W9S2
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS02510
gene id: 1769779:AUP74_RS02510
uniprot id: A0A1C9W4A0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1769779:AUP74 RS12265
gene id: 1769779:AUP74_RS12265
uniprot id: A0A1C9W9P2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1769779:AUP74 RS05990
gene id: 1769779:AUP74_RS05990
uniprot id: A0A1C9W682
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1769779:AUP74 RS01740
gene id: 1769779:AUP74_RS01740
uniprot id: A0A1C9W3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS05835
gene id: 1769779:AUP74_RS05835
uniprot id: A0A1C9W672
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1769779:AUP74 RS04395
gene id: 1769779:AUP74_RS04395
uniprot id: A0A1C9W5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1769779:AUP74 RS04595
gene id: 1769779:AUP74_RS04595
uniprot id: A0A1C9W5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1769779:AUP74 RS04430
gene id: 1769779:AUP74_RS04430
uniprot id: A0A1C9W5F5
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1769779:AUP74 RS09755
gene id: 1769779:AUP74_RS09755
uniprot id: A0A1C9W8D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS13915
gene id: 1769779:AUP74_RS13915
uniprot id: A0A1C9WAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1769779:AUP74 RS06180
gene id: 1769779:AUP74_RS06180
uniprot id: A0A1C9W6E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS16180
gene id: 1769779:AUP74_RS16180
uniprot id: A0A1C9WBU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1769779:AUP74 RS03665
gene id: 1769779:AUP74_RS03665
uniprot id: A0A1C9W4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS15445
gene id: 1769779:AUP74_RS15445
uniprot id: A0A1C9WBI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1769779:AUP74 RS13230
gene id: 1769779:AUP74_RS13230
uniprot id: A0A1C9WA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1769779:AUP74 RS12630
gene id: 1769779:AUP74_RS12630
uniprot id: A0A1C9W9X5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1769779:AUP74 RS08190
gene id: 1769779:AUP74_RS08190
uniprot id: A0A1C9W7E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1769779:AUP74 RS06240
gene id: 1769779:AUP74_RS06240
uniprot id: A0A1C9W6E8
names: Similarity
messages: Belongs to the peptidase M17 family.

1769779:AUP74 RS14800
gene id: 1769779:AUP74_RS14800
uniprot id: A0A1C9WB33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1769779:AUP74 RS10890
gene id: 1769779:AUP74_RS10890
uniprot id: A0A1C9W901
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1769779:AUP74 RS08570
gene id: 1769779:AUP74_RS08570
uniprot id: A0A1C9W7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1769779:AUP74 RS06565
gene id: 1769779:AUP74_RS06565
uniprot id: A0A1C9W6L1
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS16860
gene id: 1769779:AUP74_RS16860
uniprot id: A0A1C9WC72
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1769779:AUP74 RS11455
gene id: 1769779:AUP74_RS11455
uniprot id: A0A1C9W989
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

1769779:AUP74 RS10885
gene id: 1769779:AUP74_RS10885
uniprot id: A0A1C9W8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1769779:AUP74 RS03720
gene id: 1769779:AUP74_RS03720
uniprot id: A0A1C9W506
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1769779:AUP74 RS10375
gene id: 1769779:AUP74_RS10375
uniprot id: A0A1C9W8N8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1769779:AUP74 RS15620
gene id: 1769779:AUP74_RS15620
uniprot id: A0A1C9WBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1769779:AUP74 RS01460
gene id: 1769779:AUP74_RS01460
uniprot id: A0A1C9W3R0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1769779:AUP74 RS10460
gene id: 1769779:AUP74_RS10460
uniprot id: A0A1C9W8P7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1769779:AUP74 RS09295
gene id: 1769779:AUP74_RS09295
uniprot id: A0A1C9W856
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1769779:AUP74 RS16575
gene id: 1769779:AUP74_RS16575
uniprot id: A0A1C9WC13
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1769779:AUP74 RS16760
gene id: 1769779:AUP74_RS16760
uniprot id: A0A1C9WC74
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS07620
gene id: 1769779:AUP74_RS07620
uniprot id: A0A1C9W754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1769779:AUP74 RS01535
gene id: 1769779:AUP74_RS01535
uniprot id: A0A1C9W3Q7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1769779:AUP74 RS15380
gene id: 1769779:AUP74_RS15380
uniprot id: A0A1C9WBE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1769779:AUP74 RS00635
gene id: 1769779:AUP74_RS00635
uniprot id: A0A1C9W374
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1769779:AUP74 RS04220
gene id: 1769779:AUP74_RS04220
uniprot id: A0A1C9W5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1769779:AUP74 RS07215
gene id: 1769779:AUP74_RS07215
uniprot id: A0A1C9W6X6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1769779:AUP74 RS01675
gene id: 1769779:AUP74_RS01675
uniprot id: A0A1C9W3T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1769779:AUP74 RS06835
gene id: 1769779:AUP74_RS06835
uniprot id: A0A1C9W6P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1769779:AUP74 RS16120
gene id: 1769779:AUP74_RS16120
uniprot id: A0A1C9WBS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1769779:AUP74 RS04690
gene id: 1769779:AUP74_RS04690
uniprot id: A0A1C9W5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1769779:AUP74 RS04265
gene id: 1769779:AUP74_RS04265
uniprot id: A0A1C9W5D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1769779:AUP74 RS13355
gene id: 1769779:AUP74_RS13355
uniprot id: A0A1C9WAB6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS14375
gene id: 1769779:AUP74_RS14375
uniprot id: A0A1C9WAU6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1769779:AUP74 RS08435
gene id: 1769779:AUP74_RS08435
uniprot id: A0A1C9W7L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1769779:AUP74 RS12545
gene id: 1769779:AUP74_RS12545
uniprot id: A0A1C9W9X1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1769779:AUP74 RS00035
gene id: 1769779:AUP74_RS00035
uniprot id: A0A1C9W2W0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1769779:AUP74 RS14965
gene id: 1769779:AUP74_RS14965
uniprot id: A0A1C9WB51
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1769779:AUP74 RS13105
gene id: 1769779:AUP74_RS13105
uniprot id: A0A1C9WA53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1769779:AUP74 RS10500
gene id: 1769779:AUP74_RS10500
uniprot id: A0A1C9W8R9
names: Similarity
messages: Belongs to the UPF0045 family.

1769779:AUP74 RS05305
gene id: 1769779:AUP74_RS05305
uniprot id: A0A1C9W5X6
names: Similarity
messages: Belongs to the peptidase M16 family.

1769779:AUP74 RS16745
gene id: 1769779:AUP74_RS16745
uniprot id: A0A1C9WCA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1769779:AUP74 RS03160
gene id: 1769779:AUP74_RS03160
uniprot id: A0A1C9W4R4
names: Similarity
messages: Belongs to the pyruvate kinase family.

1769779:AUP74 RS06900
gene id: 1769779:AUP74_RS06900
uniprot id: A0A1C9W6S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1769779:AUP74 RS07990
gene id: 1769779:AUP74_RS07990
uniprot id: A0A1C9W7C3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1769779:AUP74 RS12665
gene id: 1769779:AUP74_RS12665
uniprot id: A0A1C9W9W7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1769779:AUP74 RS06490
gene id: 1769779:AUP74_RS06490
uniprot id: A0A1C9W6L0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1769779:AUP74 RS01845
gene id: 1769779:AUP74_RS01845
uniprot id: A0A1C9W3W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1769779:AUP74 RS07025
gene id: 1769779:AUP74_RS07025
uniprot id: A0A1C9W6U8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1769779:AUP74 RS15605
gene id: 1769779:AUP74_RS15605
uniprot id: A0A1C9WBI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1769779:AUP74 RS16515
gene id: 1769779:AUP74_RS16515
uniprot id: A0A1C9WC34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1769779:AUP74 RS04885
gene id: 1769779:AUP74_RS04885
uniprot id: A0A1C9W5N4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1769779:AUP74 RS03825
gene id: 1769779:AUP74_RS03825
uniprot id: A0A1C9W541
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1769779:AUP74 RS05645
gene id: 1769779:AUP74_RS05645
uniprot id: A0A1C9W617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS14710
gene id: 1769779:AUP74_RS14710
uniprot id: A0A1C9WB02
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1769779:AUP74 RS09820
gene id: 1769779:AUP74_RS09820
uniprot id: A0A1C9W8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1769779:AUP74 RS12830
gene id: 1769779:AUP74_RS12830
uniprot id: A0A1C9WA14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1769779:AUP74 RS09815
gene id: 1769779:AUP74_RS09815
uniprot id: A0A1C9W8D1
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1769779:AUP74 RS06780
gene id: 1769779:AUP74_RS06780
uniprot id: A0A1C9W6S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1769779:AUP74 RS03800
gene id: 1769779:AUP74_RS03800
uniprot id: A0A1C9W504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS05375
gene id: 1769779:AUP74_RS05375
uniprot id: A0A1C9W5Z4
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

1769779:AUP74 RS03750
gene id: 1769779:AUP74_RS03750
uniprot id: A0A1C9W4Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1769779:AUP74 RS10320
gene id: 1769779:AUP74_RS10320
uniprot id: A0A1C9W8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS12725
gene id: 1769779:AUP74_RS12725
uniprot id: A0A1C9W9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1769779:AUP74 RS09980
gene id: 1769779:AUP74_RS09980
uniprot id: A0A1C9W8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1769779:AUP74 RS14825
gene id: 1769779:AUP74_RS14825
uniprot id: A0A1C9WB39
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS10490
gene id: 1769779:AUP74_RS10490
uniprot id: A0A1C9W8Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1769779:AUP74 RS02295
gene id: 1769779:AUP74_RS02295
uniprot id: A0A1C9W457
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1769779:AUP74 RS12785
gene id: 1769779:AUP74_RS12785
uniprot id: A0A1C9WA55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1769779:AUP74 RS12860
gene id: 1769779:AUP74_RS12860
uniprot id: A0A1C9WA07
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1769779:AUP74 RS05495
gene id: 1769779:AUP74_RS05495
uniprot id: A0A1C9W621
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1769779:AUP74 RS04765
gene id: 1769779:AUP74_RS04765
uniprot id: A0A1C9W5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1769779:AUP74 RS10140
gene id: 1769779:AUP74_RS10140
uniprot id: A0A1C9W8J1
names: Similarity
messages: Belongs to the peptidase M1 family.

1769779:AUP74 RS12675
gene id: 1769779:AUP74_RS12675
uniprot id: A0A1C9W9X6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1769779:AUP74 RS05770
gene id: 1769779:AUP74_RS05770
uniprot id: A0A1C9W662
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS06825
gene id: 1769779:AUP74_RS06825
uniprot id: A0A1C9W6R4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1769779:AUP74 RS09145
gene id: 1769779:AUP74_RS09145
uniprot id: A0A1C9W7Z1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1769779:AUP74 RS13115
gene id: 1769779:AUP74_RS13115
uniprot id: A0A1C9WA59
names: Subcellular Location Annotation
messages: Membrane

1769779:AUP74 RS04455
gene id: 1769779:AUP74_RS04455
uniprot id: A0A1C9W5D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1769779:AUP74 RS02300
gene id: 1769779:AUP74_RS02300
uniprot id: A0A1C9W487
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1769779:AUP74 RS10620
gene id: 1769779:AUP74_RS10620
uniprot id: A0A1C9W8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1769779:AUP74 RS08175
gene id: 1769779:AUP74_RS08175
uniprot id: A0A1C9W7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1769779:AUP74 RS11835
gene id: 1769779:AUP74_RS11835
uniprot id: A0A1C9W9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1769779:AUP74 RS07850
gene id: 1769779:AUP74_RS07850
uniprot id: A0A1C9W784
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1769779:AUP74 RS00605
gene id: 1769779:AUP74_RS00605
uniprot id: A0A1C9W378
names: Similarity
messages: Belongs to the UPF0260 family.