1765967:BW247 RS02225
gene id: 1765967:BW247_RS02225
uniprot id: A0A1P8UDW6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1765967:BW247 RS15110
gene id: 1765967:BW247_RS15110
uniprot id: A0A1P8UK95
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1765967:BW247 RS13965
gene id: 1765967:BW247_RS13965
uniprot id: A0A1P8UJX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1765967:BW247 RS13160
gene id: 1765967:BW247_RS13160
uniprot id: A0A1P8UJF8
names: Similarity
messages: Belongs to the ArsC family.

1765967:BW247 RS09760
gene id: 1765967:BW247_RS09760
uniprot id: A0A1P8UHN8
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS05230
gene id: 1765967:BW247_RS05230
uniprot id: A0A1P8UFF4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1765967:BW247 RS03425
gene id: 1765967:BW247_RS03425
uniprot id: A0A1P8UL34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

1765967:BW247 RS13290
gene id: 1765967:BW247_RS13290
uniprot id: A0A1P8UJG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1765967:BW247 RS14335
gene id: 1765967:BW247_RS14335
uniprot id: A0A1P8UJU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1765967:BW247 RS11395
gene id: 1765967:BW247_RS11395
uniprot id: A0A1P8UIF4
names: Similarity
messages: Belongs to the threonine synthase family.

1765967:BW247 RS14730
gene id: 1765967:BW247_RS14730
uniprot id: A0A1P8UK32
names: Similarity
messages: Belongs to the GARS family.

1765967:BW247 RS15295
gene id: 1765967:BW247_RS15295
uniprot id: A0A1P8UKC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1765967:BW247 RS11915
gene id: 1765967:BW247_RS11915
uniprot id: A0A1P8UIQ7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1765967:BW247 RS05905
gene id: 1765967:BW247_RS05905
uniprot id: A0A1P8UFS9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS04875
gene id: 1765967:BW247_RS04875
uniprot id: A0A1P8UFH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1765967:BW247 RS11035
gene id: 1765967:BW247_RS11035
uniprot id: A0A1P8UI99
names: Similarity
messages: Belongs to the YggT family.

1765967:BW247 RS15840
gene id: 1765967:BW247_RS15840
uniprot id: A0A1P8UKK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1765967:BW247 RS07800
gene id: 1765967:BW247_RS07800
uniprot id: A0A1P8UGP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS11210
gene id: 1765967:BW247_RS11210
uniprot id: A0A1P8UIB3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1765967:BW247 RS11610
gene id: 1765967:BW247_RS11610
uniprot id: A0A1P8UIM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1765967:BW247 RS12765
gene id: 1765967:BW247_RS12765
uniprot id: A0A1P8UJ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1765967:BW247 RS11560
gene id: 1765967:BW247_RS11560
uniprot id: A0A1P8UIH9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1765967:BW247 RS04060
gene id: 1765967:BW247_RS04060
uniprot id: A0A1P8UEX5
names: Similarity
messages: Belongs to the CFA/CMAS family.

1765967:BW247 RS14700
gene id: 1765967:BW247_RS14700
uniprot id: A0A1P8UK20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1765967:BW247 RS06520
gene id: 1765967:BW247_RS06520
uniprot id: A0A1P8UG02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS09140
gene id: 1765967:BW247_RS09140
uniprot id: A0A1P8UHB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1765967:BW247 RS03410
gene id: 1765967:BW247_RS03410
uniprot id: A0A1P8UEH7
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS13760
gene id: 1765967:BW247_RS13760
uniprot id: A0A1P8UJL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1765967:BW247 RS00905
gene id: 1765967:BW247_RS00905
uniprot id: A0A1P8UDI9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1765967:BW247 RS06030
gene id: 1765967:BW247_RS06030
uniprot id: A0A1P8UFW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1765967:BW247 RS16100
gene id: 1765967:BW247_RS16100
uniprot id: A0A1P8UKT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1765967:BW247 RS13870
gene id: 1765967:BW247_RS13870
uniprot id: A0A1P8UJM6
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1765967:BW247 RS10950
gene id: 1765967:BW247_RS10950
uniprot id: A0A1P8UIF2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1765967:BW247 RS11960
gene id: 1765967:BW247_RS11960
uniprot id: A0A1P8UIQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1765967:BW247 RS12810
gene id: 1765967:BW247_RS12810
uniprot id: A0A1P8UJ41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS11470
gene id: 1765967:BW247_RS11470
uniprot id: A0A1P8UIG0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS01915
gene id: 1765967:BW247_RS01915
uniprot id: A0A1P8UDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS08245
gene id: 1765967:BW247_RS08245
uniprot id: A0A1P8UGV9
names: Similarity
messages: Belongs to the UPF0166 family.

1765967:BW247 RS01485
gene id: 1765967:BW247_RS01485
uniprot id: A0A1P8UDL1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1765967:BW247 RS11500
gene id: 1765967:BW247_RS11500
uniprot id: A0A1P8UIK7
names: Similarity
messages: Belongs to the peptidase M17 family.

1765967:BW247 RS00395
gene id: 1765967:BW247_RS00395
uniprot id: A0A1P8UD06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1765967:BW247 RS06355
gene id: 1765967:BW247_RS06355
uniprot id: A0A1P8UG68
names: Similarity
messages: Belongs to the peptidase U62 family.

1765967:BW247 RS00035
gene id: 1765967:BW247_RS00035
uniprot id: A0A1P8UCW1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1765967:BW247 RS09225
gene id: 1765967:BW247_RS09225
uniprot id: A0A1P8UHE5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1765967:BW247 RS14615
gene id: 1765967:BW247_RS14615
uniprot id: A0A1P8ULM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS03035
gene id: 1765967:BW247_RS03035
uniprot id: A0A1P8UEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1765967:BW247 RS02060
gene id: 1765967:BW247_RS02060
uniprot id: A0A1P8UDU0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1765967:BW247 RS11600
gene id: 1765967:BW247_RS11600
uniprot id: A0A1P8UIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1765967:BW247 RS00935
gene id: 1765967:BW247_RS00935
uniprot id: A0A1P8UDB3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1765967:BW247 RS10785
gene id: 1765967:BW247_RS10785
uniprot id: A0A1P8UI43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1765967:BW247 RS07190
gene id: 1765967:BW247_RS07190
uniprot id: A0A1P8UGH1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1765967:BW247 RS06290
gene id: 1765967:BW247_RS06290
uniprot id: A0A1P8UG03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1765967:BW247 RS10220
gene id: 1765967:BW247_RS10220
uniprot id: A0A1P8UHX1
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1765967:BW247 RS08065
gene id: 1765967:BW247_RS08065
uniprot id: A0A1P8ULC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1765967:BW247 RS10790
gene id: 1765967:BW247_RS10790
uniprot id: A0A1P8UI98
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS12655
gene id: 1765967:BW247_RS12655
uniprot id: A0A1P8UJ11
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1765967:BW247 RS05790
gene id: 1765967:BW247_RS05790
uniprot id: A0A1P8UFQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1765967:BW247 RS06015
gene id: 1765967:BW247_RS06015
uniprot id: A0A1P8UFT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1765967:BW247 RS07105
gene id: 1765967:BW247_RS07105
uniprot id: A0A1P8UGB1
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS02810
gene id: 1765967:BW247_RS02810
uniprot id: A0A1P8UEB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS09985
gene id: 1765967:BW247_RS09985
uniprot id: A0A1P8UHT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1765967:BW247 RS01400
gene id: 1765967:BW247_RS01400
uniprot id: A0A1P8UDJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS07675
gene id: 1765967:BW247_RS07675
uniprot id: A0A1P8UGL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1765967:BW247 RS15520
gene id: 1765967:BW247_RS15520
uniprot id: A0A1P8UKF1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1765967:BW247 RS07065
gene id: 1765967:BW247_RS07065
uniprot id: A0A1P8UGA6
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1765967:BW247 RS00740
gene id: 1765967:BW247_RS00740
uniprot id: A0A1P8UD56
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1765967:BW247 RS00015
gene id: 1765967:BW247_RS00015
uniprot id: A0A1P8UD21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1765967:BW247 RS08170
gene id: 1765967:BW247_RS08170
uniprot id: A0A1P8UGW8
names: Similarity
messages: Belongs to the YfgM family.

1765967:BW247 RS08925
gene id: 1765967:BW247_RS08925
uniprot id: A0A1P8UH95
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1765967:BW247 RS02275
gene id: 1765967:BW247_RS02275
uniprot id: A0A1P8UDX5
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS11225
gene id: 1765967:BW247_RS11225
uniprot id: A0A1P8UID0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1765967:BW247 RS13950
gene id: 1765967:BW247_RS13950
uniprot id: A0A1P8UJQ2
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1765967:BW247 RS16140
gene id: 1765967:BW247_RS16140
uniprot id: A0A1P8UKW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS03505
gene id: 1765967:BW247_RS03505
uniprot id: A0A1P8UEL0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS02570
gene id: 1765967:BW247_RS02570
uniprot id: A0A1P8UE80
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1765967:BW247 RS15335
gene id: 1765967:BW247_RS15335
uniprot id: A0A1P8UKF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1765967:BW247 RS12255
gene id: 1765967:BW247_RS12255
uniprot id: A0A1P8UIW0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1765967:BW247 RS15515
gene id: 1765967:BW247_RS15515
uniprot id: A0A1P8UKI5
names: Similarity
messages: Belongs to the glutamate synthase family.

1765967:BW247 RS12850
gene id: 1765967:BW247_RS12850
uniprot id: A0A1P8UJ51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1765967:BW247 RS14620
gene id: 1765967:BW247_RS14620
uniprot id: A0A1P8ULP5
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS09265
gene id: 1765967:BW247_RS09265
uniprot id: A0A1P8UHF0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1765967:BW247 RS13530
gene id: 1765967:BW247_RS13530
uniprot id: A0A1P8UJH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1765967:BW247 RS00340
gene id: 1765967:BW247_RS00340
uniprot id: A0A1P8UD43
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS09565
gene id: 1765967:BW247_RS09565
uniprot id: A0A1P8UHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1765967:BW247 RS07915
gene id: 1765967:BW247_RS07915
uniprot id: A0A1P8UGQ4
names: Similarity
messages: Belongs to the MotB family.

1765967:BW247 RS01515
gene id: 1765967:BW247_RS01515
uniprot id: A0A1P8UDL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1765967:BW247 RS00990
gene id: 1765967:BW247_RS00990
uniprot id: A0A1P8UDH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1765967:BW247 RS09580
gene id: 1765967:BW247_RS09580
uniprot id: A0A1P8UHM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1765967:BW247 RS05825
gene id: 1765967:BW247_RS05825
uniprot id: A0A1P8UFR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1765967:BW247 RS03605
gene id: 1765967:BW247_RS03605
uniprot id: A0A1P8UEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1765967:BW247 RS12955
gene id: 1765967:BW247_RS12955
uniprot id: A0A1P8UJ85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1765967:BW247 RS00530
gene id: 1765967:BW247_RS00530
uniprot id: A0A1P8UD32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1765967:BW247 RS16090
gene id: 1765967:BW247_RS16090
uniprot id: A0A1P8UKS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1765967:BW247 RS13300
gene id: 1765967:BW247_RS13300
uniprot id: A0A1P8UJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1765967:BW247 RS01760
gene id: 1765967:BW247_RS01760
uniprot id: A0A1P8UDX4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS13840
gene id: 1765967:BW247_RS13840
uniprot id: A0A1P8UJQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1765967:BW247 RS04555
gene id: 1765967:BW247_RS04555
uniprot id: A0A1P8UF88
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1765967:BW247 RS09965
gene id: 1765967:BW247_RS09965
uniprot id: A0A1P8UHU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1765967:BW247 RS07865
gene id: 1765967:BW247_RS07865
uniprot id: A0A1P8UGM9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1765967:BW247 RS03730
gene id: 1765967:BW247_RS03730
uniprot id: A0A1P8UEU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS13765
gene id: 1765967:BW247_RS13765
uniprot id: A0A1P8UJL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1765967:BW247 RS04030
gene id: 1765967:BW247_RS04030
uniprot id: A0A1P8UEW2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1765967:BW247 RS13895
gene id: 1765967:BW247_RS13895
uniprot id: A0A1P8ULM3
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS01240
gene id: 1765967:BW247_RS01240
uniprot id: A0A1P8UDF2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1765967:BW247 RS02915
gene id: 1765967:BW247_RS02915
uniprot id: A0A1P8UE82
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclic amide hydrolase (CyAH) family.
messages: Homotetramer.
messages: Inhibited by barbituric acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.
messages: The monomer structure is formed from three repeating units (RUs) that share the same structure as one another. The monomer, the active site and substrate all possess threefold rotational symmetry, to the extent that the active site possesses three potential Ser-Lys catalytic dyads. It is possible that any or all of the three active-site serines may act as nucleophile (albeit only one can do so per catalytic cycle).

1765967:BW247 RS09155
gene id: 1765967:BW247_RS09155
uniprot id: A0A1P8UHB2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1765967:BW247 RS06250
gene id: 1765967:BW247_RS06250
uniprot id: A0A1P8UG64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1765967:BW247 RS04630
gene id: 1765967:BW247_RS04630
uniprot id: A0A1P8UF95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1765967:BW247 RS13185
gene id: 1765967:BW247_RS13185
uniprot id: A0A1P8ULK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1765967:BW247 RS10820
gene id: 1765967:BW247_RS10820
uniprot id: A0A1P8ULN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1765967:BW247 RS10505
gene id: 1765967:BW247_RS10505
uniprot id: A0A1P8UHY9
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1765967:BW247 RS10730
gene id: 1765967:BW247_RS10730
uniprot id: A0A1P8UI44
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1765967:BW247 RS03800
gene id: 1765967:BW247_RS03800
uniprot id: A0A1P8UET5
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS14750
gene id: 1765967:BW247_RS14750
uniprot id: A0A1P8UK33
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1765967:BW247 RS04390
gene id: 1765967:BW247_RS04390
uniprot id: A0A1P8UF00
names: Similarity
messages: Belongs to the GST superfamily. Omega family.

1765967:BW247 RS14705
gene id: 1765967:BW247_RS14705
uniprot id: A0A1P8UKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1765967:BW247 RS02625
gene id: 1765967:BW247_RS02625
uniprot id: A0A1P8UE40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1765967:BW247 RS02045
gene id: 1765967:BW247_RS02045
uniprot id: A0A1P8UE17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1765967:BW247 RS07455
gene id: 1765967:BW247_RS07455
uniprot id: A0A1P8UGG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1765967:BW247 RS04405
gene id: 1765967:BW247_RS04405
uniprot id: A0A1P8UEZ8
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS02380
gene id: 1765967:BW247_RS02380
uniprot id: A0A1P8UE91
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1765967:BW247 RS06510
gene id: 1765967:BW247_RS06510
uniprot id: A0A1P8UG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS06955
gene id: 1765967:BW247_RS06955
uniprot id: A0A1P8UG82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1765967:BW247 RS05795
gene id: 1765967:BW247_RS05795
uniprot id: A0A1P8UL52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1765967:BW247 RS10375
gene id: 1765967:BW247_RS10375
uniprot id: A0A1P8UI54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1765967:BW247 RS00085
gene id: 1765967:BW247_RS00085
uniprot id: A0A1P8UCX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1765967:BW247 RS02975
gene id: 1765967:BW247_RS02975
uniprot id: A0A1P8UL00
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1765967:BW247 RS14190
gene id: 1765967:BW247_RS14190
uniprot id: A0A1P8UJW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1765967:BW247 RS15625
gene id: 1765967:BW247_RS15625
uniprot id: A0A1P8UKI9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1765967:BW247 RS07655
gene id: 1765967:BW247_RS07655
uniprot id: A0A1P8UGK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1765967:BW247 RS15860
gene id: 1765967:BW247_RS15860
uniprot id: A0A1P8UKK8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1765967:BW247 RS07855
gene id: 1765967:BW247_RS07855
uniprot id: A0A1P8UGP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1765967:BW247 RS13720
gene id: 1765967:BW247_RS13720
uniprot id: A0A1P8UJK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1765967:BW247 RS07195
gene id: 1765967:BW247_RS07195
uniprot id: A0A1P8UGJ2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1765967:BW247 RS12835
gene id: 1765967:BW247_RS12835
uniprot id: A0A1P8UJ87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS15510
gene id: 1765967:BW247_RS15510
uniprot id: A0A1P8UKJ7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1765967:BW247 RS13565
gene id: 1765967:BW247_RS13565
uniprot id: A0A1P8UJJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1765967:BW247 RS08960
gene id: 1765967:BW247_RS08960
uniprot id: A0A1P8UH85
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1765967:BW247 RS03615
gene id: 1765967:BW247_RS03615
uniprot id: A0A1P8UET1
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1765967:BW247 RS01470
gene id: 1765967:BW247_RS01470
uniprot id: A0A1P8UDI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS05215
gene id: 1765967:BW247_RS05215
uniprot id: A0A1P8UFI9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1765967:BW247 RS07780
gene id: 1765967:BW247_RS07780
uniprot id: A0A1P8UGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1765967:BW247 RS00025
gene id: 1765967:BW247_RS00025
uniprot id: A0A1P8UD28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1765967:BW247 RS07385
gene id: 1765967:BW247_RS07385
uniprot id: A0A1P8UGP2
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

1765967:BW247 RS02970
gene id: 1765967:BW247_RS02970
uniprot id: A0A1P8UE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1765967:BW247 RS09525
gene id: 1765967:BW247_RS09525
uniprot id: A0A1P8UHL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1765967:BW247 RS11295
gene id: 1765967:BW247_RS11295
uniprot id: A0A1P8UID4
names: Similarity
messages: Belongs to the citrate synthase family.

1765967:BW247 RS00010
gene id: 1765967:BW247_RS00010
uniprot id: A0A1P8UD17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1765967:BW247 RS01295
gene id: 1765967:BW247_RS01295
uniprot id: A0A1P8UDI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1765967:BW247 RS12800
gene id: 1765967:BW247_RS12800
uniprot id: A0A1P8UJ62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS11455
gene id: 1765967:BW247_RS11455
uniprot id: A0A1P8UIG5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1765967:BW247 RS02990
gene id: 1765967:BW247_RS02990
uniprot id: A0A1P8UEB1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1765967:BW247 RS00550
gene id: 1765967:BW247_RS00550
uniprot id: A0A1P8UDC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1765967:BW247 RS02780
gene id: 1765967:BW247_RS02780
uniprot id: A0A1P8UE98
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1765967:BW247 RS14305
gene id: 1765967:BW247_RS14305
uniprot id: A0A1P8UJV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1765967:BW247 RS11020
gene id: 1765967:BW247_RS11020
uniprot id: A0A1P8UID8
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS03475
gene id: 1765967:BW247_RS03475
uniprot id: A0A1P8UEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1765967:BW247 RS01755
gene id: 1765967:BW247_RS01755
uniprot id: A0A1P8UDN2
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS00965
gene id: 1765967:BW247_RS00965
uniprot id: A0A1P8UD96
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1765967:BW247 RS07660
gene id: 1765967:BW247_RS07660
uniprot id: A0A1P8UGT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1765967:BW247 RS02465
gene id: 1765967:BW247_RS02465
uniprot id: A0A1P8UE06
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1765967:BW247 RS10765
gene id: 1765967:BW247_RS10765
uniprot id: A0A1P8UI60
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1765967:BW247 RS12785
gene id: 1765967:BW247_RS12785
uniprot id: A0A1P8UJ33
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS02960
gene id: 1765967:BW247_RS02960
uniprot id: A0A1P8UED3
names: Similarity
messages: Belongs to the UPF0260 family.

1765967:BW247 RS04340
gene id: 1765967:BW247_RS04340
uniprot id: A0A1P8UEZ4
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1765967:BW247 RS09995
gene id: 1765967:BW247_RS09995
uniprot id: A0A1P8UHQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1765967:BW247 RS00715
gene id: 1765967:BW247_RS00715
uniprot id: A0A1P8UD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS02310
gene id: 1765967:BW247_RS02310
uniprot id: A0A1P8UE22
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1765967:BW247 RS04845
gene id: 1765967:BW247_RS04845
uniprot id: A0A1P8UFD0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1765967:BW247 RS03560
gene id: 1765967:BW247_RS03560
uniprot id: A0A1P8UEP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1765967:BW247 RS13970
gene id: 1765967:BW247_RS13970
uniprot id: A0A1P8UJP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1765967:BW247 RS15835
gene id: 1765967:BW247_RS15835
uniprot id: A0A1P8UKK4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1765967:BW247 RS08090
gene id: 1765967:BW247_RS08090
uniprot id: A0A1P8UGU8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1765967:BW247 RS02755
gene id: 1765967:BW247_RS02755
uniprot id: A0A1P8UE72
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1765967:BW247 RS06525
gene id: 1765967:BW247_RS06525
uniprot id: A0A1P8UG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1765967:BW247 RS13685
gene id: 1765967:BW247_RS13685
uniprot id: A0A1P8UJP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS08145
gene id: 1765967:BW247_RS08145
uniprot id: A0A1P8UGV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1765967:BW247 RS09605
gene id: 1765967:BW247_RS09605
uniprot id: A0A1P8UHL0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1765967:BW247 RS00235
gene id: 1765967:BW247_RS00235
uniprot id: A0A1P8UD58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1765967:BW247 RS11830
gene id: 1765967:BW247_RS11830
uniprot id: A0A1P8UIR0
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS13615
gene id: 1765967:BW247_RS13615
uniprot id: A0A1P8UJJ4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS00075
gene id: 1765967:BW247_RS00075
uniprot id: A0A1P8UCW4
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1765967:BW247 RS07785
gene id: 1765967:BW247_RS07785
uniprot id: A0A1P8UGM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1765967:BW247 RS13475
gene id: 1765967:BW247_RS13475
uniprot id: A0A1P8UJE9
names: Similarity
messages: Belongs to the glyoxalase I family.

1765967:BW247 RS04240
gene id: 1765967:BW247_RS04240
uniprot id: A0A1P8UF23
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1765967:BW247 RS03355
gene id: 1765967:BW247_RS03355
uniprot id: A0A1P8UEL1
names: Similarity
messages: Belongs to the group II decarboxylase family.

1765967:BW247 RS09970
gene id: 1765967:BW247_RS09970
uniprot id: A0A1P8UHQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS10840
gene id: 1765967:BW247_RS10840
uniprot id: A0A1P8UI66
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1765967:BW247 RS07100
gene id: 1765967:BW247_RS07100
uniprot id: A0A1P8UGA5
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1765967:BW247 RS03030
gene id: 1765967:BW247_RS03030
uniprot id: A0A1P8UEA3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1765967:BW247 RS09630
gene id: 1765967:BW247_RS09630
uniprot id: A0A1P8UHK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1765967:BW247 RS17195
gene id: 1765967:BW247_RS17195
uniprot id: A0A1P8UEB7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1765967:BW247 RS14740
gene id: 1765967:BW247_RS14740
uniprot id: A0A1P8UK30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1765967:BW247 RS00485
gene id: 1765967:BW247_RS00485
uniprot id: A0A1P8UD16
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1765967:BW247 RS02085
gene id: 1765967:BW247_RS02085
uniprot id: A0A1P8UDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1765967:BW247 RS11540
gene id: 1765967:BW247_RS11540
uniprot id: A0A1P8UIP9
names: Similarity
messages: Belongs to the PrpD family.

1765967:BW247 RS03965
gene id: 1765967:BW247_RS03965
uniprot id: A0A1P8UEW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1765967:BW247 RS07480
gene id: 1765967:BW247_RS07480
uniprot id: A0A1P8UGI7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS12065
gene id: 1765967:BW247_RS12065
uniprot id: A0A1P8ULI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS12775
gene id: 1765967:BW247_RS12775
uniprot id: A0A1P8UJ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS14960
gene id: 1765967:BW247_RS14960
uniprot id: A0A1P8UK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS03485
gene id: 1765967:BW247_RS03485
uniprot id: A0A1P8UEI4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1765967:BW247 RS06315
gene id: 1765967:BW247_RS06315
uniprot id: A0A1P8ULE3
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS04505
gene id: 1765967:BW247_RS04505
uniprot id: A0A1P8UF71
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1765967:BW247 RS00245
gene id: 1765967:BW247_RS00245
uniprot id: A0A1P8UD69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1765967:BW247 RS09060
gene id: 1765967:BW247_RS09060
uniprot id: A0A1P8UHA1
names: Similarity
messages: Belongs to the UPF0276 family.

1765967:BW247 RS15230
gene id: 1765967:BW247_RS15230
uniprot id: A0A1P8UKB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS06430
gene id: 1765967:BW247_RS06430
uniprot id: A0A1P8UG91
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1765967:BW247 RS15035
gene id: 1765967:BW247_RS15035
uniprot id: A0A1P8UKF4
names: Similarity
messages: Belongs to the fructosamine kinase family.

1765967:BW247 RS13310
gene id: 1765967:BW247_RS13310
uniprot id: A0A1P8UJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS03275
gene id: 1765967:BW247_RS03275
uniprot id: A0A1P8UEN3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1765967:BW247 RS07450
gene id: 1765967:BW247_RS07450
uniprot id: A0A1P8UGI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1765967:BW247 RS03815
gene id: 1765967:BW247_RS03815
uniprot id: A0A1P8UEP3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1765967:BW247 RS09700
gene id: 1765967:BW247_RS09700
uniprot id: A0A1P8UHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1765967:BW247 RS00775
gene id: 1765967:BW247_RS00775
uniprot id: A0A1P8UD67
names: Similarity
messages: Belongs to the asparagine synthetase family.

1765967:BW247 RS00870
gene id: 1765967:BW247_RS00870
uniprot id: A0A1P8UDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1765967:BW247 RS14485
gene id: 1765967:BW247_RS14485
uniprot id: A0A1P8UJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1765967:BW247 RS09840
gene id: 1765967:BW247_RS09840
uniprot id: A0A1P8UHN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1765967:BW247 RS15255
gene id: 1765967:BW247_RS15255
uniprot id: A0A1P8UKB8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1765967:BW247 RS14550
gene id: 1765967:BW247_RS14550
uniprot id: A0A1P8ULN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS10390
gene id: 1765967:BW247_RS10390
uniprot id: A0A1P8UI22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1765967:BW247 RS06660
gene id: 1765967:BW247_RS06660
uniprot id: A0A1P8UG45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1765967:BW247 RS11430
gene id: 1765967:BW247_RS11430
uniprot id: A0A1P8UIN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1765967:BW247 RS11760
gene id: 1765967:BW247_RS11760
uniprot id: A0A1P8UIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS13115
gene id: 1765967:BW247_RS13115
uniprot id: A0A1P8UJA9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1765967:BW247 RS04470
gene id: 1765967:BW247_RS04470
uniprot id: A0A1P8UF05
names: Cofactor
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1765967:BW247 RS09705
gene id: 1765967:BW247_RS09705
uniprot id: A0A1P8UHR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1765967:BW247 RS02865
gene id: 1765967:BW247_RS02865
uniprot id: A0A1P8UE94
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1765967:BW247 RS09500
gene id: 1765967:BW247_RS09500
uniprot id: A0A1P8UHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1765967:BW247 RS08075
gene id: 1765967:BW247_RS08075
uniprot id: A0A1P8UGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1765967:BW247 RS14105
gene id: 1765967:BW247_RS14105
uniprot id: A0A1P8UJS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1765967:BW247 RS02690
gene id: 1765967:BW247_RS02690
uniprot id: A0A1P8UE49
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1765967:BW247 RS10650
gene id: 1765967:BW247_RS10650
uniprot id: A0A1P8UIA4
names: Similarity
messages: Belongs to the FemABX family.

1765967:BW247 RS14690
gene id: 1765967:BW247_RS14690
uniprot id: A0A1P8UK26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Binds zinc. Could be an important component of the zinc-balancing mechanism.
messages: Periplasm

1765967:BW247 RS03710
gene id: 1765967:BW247_RS03710
uniprot id: A0A1P8UEV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1765967:BW247 RS14365
gene id: 1765967:BW247_RS14365
uniprot id: A0A1P8UJW7
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS15775
gene id: 1765967:BW247_RS15775
uniprot id: A0A1P8ULP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS02775
gene id: 1765967:BW247_RS02775
uniprot id: A0A1P8UEC7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1765967:BW247 RS08275
gene id: 1765967:BW247_RS08275
uniprot id: A0A1P8ULB3
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS03170
gene id: 1765967:BW247_RS03170
uniprot id: A0A1P8UEI1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS01720
gene id: 1765967:BW247_RS01720
uniprot id: A0A1P8UDS8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1765967:BW247 RS11770
gene id: 1765967:BW247_RS11770
uniprot id: A0A1P8UIM0
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS13735
gene id: 1765967:BW247_RS13735
uniprot id: A0A1P8UJT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1765967:BW247 RS04640
gene id: 1765967:BW247_RS04640
uniprot id: A0A1P8UF32
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1765967:BW247 RS05890
gene id: 1765967:BW247_RS05890
uniprot id: A0A1P8UFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS01335
gene id: 1765967:BW247_RS01335
uniprot id: A0A1P8UL02
names: Similarity
messages: Belongs to the CFA/CMAS family.

1765967:BW247 RS09895
gene id: 1765967:BW247_RS09895
uniprot id: A0A1P8UHU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1765967:BW247 RS08225
gene id: 1765967:BW247_RS08225
uniprot id: A0A1P8UGX6
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1765967:BW247 RS15445
gene id: 1765967:BW247_RS15445
uniprot id: A0A1P8UKI6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1765967:BW247 RS15170
gene id: 1765967:BW247_RS15170
uniprot id: A0A1P8UKC2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1765967:BW247 RS00040
gene id: 1765967:BW247_RS00040
uniprot id: A0A1P8UCW5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1765967:BW247 RS10985
gene id: 1765967:BW247_RS10985
uniprot id: A0A1P8UI89
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1765967:BW247 RS11735
gene id: 1765967:BW247_RS11735
uniprot id: A0A1P8UIN5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS11985
gene id: 1765967:BW247_RS11985
uniprot id: A0A1P8UIR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS11260
gene id: 1765967:BW247_RS11260
uniprot id: A0A1P8UIC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1765967:BW247 RS05460
gene id: 1765967:BW247_RS05460
uniprot id: A0A1P8UFP8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS04200
gene id: 1765967:BW247_RS04200
uniprot id: A0A1P8UEZ0
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1765967:BW247 RS02070
gene id: 1765967:BW247_RS02070
uniprot id: A0A1P8UDX8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1765967:BW247 RS08025
gene id: 1765967:BW247_RS08025
uniprot id: A0A1P8UGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS14865
gene id: 1765967:BW247_RS14865
uniprot id: A0A1P8UK56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS01630
gene id: 1765967:BW247_RS01630
uniprot id: A0A1P8UDU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS08080
gene id: 1765967:BW247_RS08080
uniprot id: A0A1P8UGT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1765967:BW247 RS00090
gene id: 1765967:BW247_RS00090
uniprot id: A0A1P8UCX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1765967:BW247 RS10780
gene id: 1765967:BW247_RS10780
uniprot id: A0A1P8UI58
names: Similarity
messages: Belongs to the MlaA family.

1765967:BW247 RS14325
gene id: 1765967:BW247_RS14325
uniprot id: A0A1P8UJX5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1765967:BW247 RS09105
gene id: 1765967:BW247_RS09105
uniprot id: A0A1P8UHD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1765967:BW247 RS07060
gene id: 1765967:BW247_RS07060
uniprot id: A0A1P8UGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1765967:BW247 RS13325
gene id: 1765967:BW247_RS13325
uniprot id: A0A1P8UJI3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1765967:BW247 RS06275
gene id: 1765967:BW247_RS06275
uniprot id: A0A1P8UFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS15525
gene id: 1765967:BW247_RS15525
uniprot id: A0A1P8UKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1765967:BW247 RS13085
gene id: 1765967:BW247_RS13085
uniprot id: A0A1P8UJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1765967:BW247 RS13780
gene id: 1765967:BW247_RS13780
uniprot id: A0A1P8UJN5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1765967:BW247 RS09380
gene id: 1765967:BW247_RS09380
uniprot id: A0A1P8UHH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS15360
gene id: 1765967:BW247_RS15360
uniprot id: A0A1P8UKD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1765967:BW247 RS13835
gene id: 1765967:BW247_RS13835
uniprot id: A0A1P8UJQ0
names: Similarity
messages: Belongs to the thioredoxin family.

1765967:BW247 RS07895
gene id: 1765967:BW247_RS07895
uniprot id: A0A1P8UGY0
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1765967:BW247 RS15320
gene id: 1765967:BW247_RS15320
uniprot id: A0A1P8UKJ9
names: Similarity
messages: Belongs to the GSP E family.

1765967:BW247 RS00330
gene id: 1765967:BW247_RS00330
uniprot id: A0A1P8UCZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1765967:BW247 RS01375
gene id: 1765967:BW247_RS01375
uniprot id: A0A1P8UDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1765967:BW247 RS03720
gene id: 1765967:BW247_RS03720
uniprot id: A0A1P8UER8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1765967:BW247 RS02910
gene id: 1765967:BW247_RS02910
uniprot id: A0A1P8UEB0
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS13175
gene id: 1765967:BW247_RS13175
uniprot id: A0A1P8UJE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1765967:BW247 RS10885
gene id: 1765967:BW247_RS10885
uniprot id: A0A1P8UI67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1765967:BW247 RS13490
gene id: 1765967:BW247_RS13490
uniprot id: A0A1P8UJF9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1765967:BW247 RS11425
gene id: 1765967:BW247_RS11425
uniprot id: A0A1P8UIF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1765967:BW247 RS07870
gene id: 1765967:BW247_RS07870
uniprot id: A0A1P8UGS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1765967:BW247 RS03735
gene id: 1765967:BW247_RS03735
uniprot id: A0A1P8UES5
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1765967:BW247 RS03975
gene id: 1765967:BW247_RS03975
uniprot id: A0A1P8UEV2
names: Similarity
messages: Belongs to the Gfa family.

1765967:BW247 RS14260
gene id: 1765967:BW247_RS14260
uniprot id: A0A1P8ULL7
names: Similarity
messages: Belongs to the UPF0250 family.

1765967:BW247 RS15900
gene id: 1765967:BW247_RS15900
uniprot id: A0A1P8UKP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS15855
gene id: 1765967:BW247_RS15855
uniprot id: A0A1P8UKL8
names: Similarity
messages: Belongs to the Smg family.

1765967:BW247 RS13545
gene id: 1765967:BW247_RS13545
uniprot id: A0A1P8UJH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1765967:BW247 RS03660
gene id: 1765967:BW247_RS03660
uniprot id: A0A1P8UEL6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1765967:BW247 RS05720
gene id: 1765967:BW247_RS05720
uniprot id: A0A1P8UFQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1765967:BW247 RS15975
gene id: 1765967:BW247_RS15975
uniprot id: A0A1P8UKP9
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS00880
gene id: 1765967:BW247_RS00880
uniprot id: A0A1P8UD86
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1765967:BW247 RS03245
gene id: 1765967:BW247_RS03245
uniprot id: A0A1P8UEL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1765967:BW247 RS09335
gene id: 1765967:BW247_RS09335
uniprot id: A0A1P8UHL7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclic amide hydrolase (CyAH) family.
messages: Cyclic amide hydrolase of unknown substrate specificity. Catalyzes the hydrolytic ring-opening of a cyclic amide. Does not act on cyanuric acid nor barbituric acid.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The monomer structure is formed from three repeating units (RUs) that share the same structure as one another. The monomer and the active site possess nearly threefold rotational symmetry, to the extent that the active site possesses three potential Ser-Lys catalytic dyads, but one of the 3 active site surfaces varies in composition suggesting it is involved in confering substrate specificity.

1765967:BW247 RS08070
gene id: 1765967:BW247_RS08070
uniprot id: A0A1P8UGZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1765967:BW247 RS13880
gene id: 1765967:BW247_RS13880
uniprot id: A0A1P8UJP4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1765967:BW247 RS00670
gene id: 1765967:BW247_RS00670
uniprot id: A0A1P8UDE1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1765967:BW247 RS00490
gene id: 1765967:BW247_RS00490
uniprot id: A0A1P8UKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1765967:BW247 RS14065
gene id: 1765967:BW247_RS14065
uniprot id: A0A1P8UJT9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1765967:BW247 RS01105
gene id: 1765967:BW247_RS01105
uniprot id: A0A1P8UDC9
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS05830
gene id: 1765967:BW247_RS05830
uniprot id: A0A1P8UFQ5
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1765967:BW247 RS15165
gene id: 1765967:BW247_RS15165
uniprot id: A0A1P8UKE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1765967:BW247 RS13985
gene id: 1765967:BW247_RS13985
uniprot id: A0A1P8UJR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1765967:BW247 RS03360
gene id: 1765967:BW247_RS03360
uniprot id: A0A1P8UEG9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS00875
gene id: 1765967:BW247_RS00875
uniprot id: A0A1P8UDG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1765967:BW247 RS07885
gene id: 1765967:BW247_RS07885
uniprot id: A0A1P8UGR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1765967:BW247 RS02385
gene id: 1765967:BW247_RS02385
uniprot id: A0A1P8UKX0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1765967:BW247 RS09415
gene id: 1765967:BW247_RS09415
uniprot id: A0A1P8UHH7
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1765967:BW247 RS14345
gene id: 1765967:BW247_RS14345
uniprot id: A0A1P8UJX3
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1765967:BW247 RS13710
gene id: 1765967:BW247_RS13710
uniprot id: A0A1P8UJK7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1765967:BW247 RS04275
gene id: 1765967:BW247_RS04275
uniprot id: A0A1P8UEY2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1765967:BW247 RS02655
gene id: 1765967:BW247_RS02655
uniprot id: A0A1P8UE71
names: Similarity
messages: Belongs to the UPF0102 family.

1765967:BW247 RS03075
gene id: 1765967:BW247_RS03075
uniprot id: A0A1P8UEE7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1765967:BW247 RS06650
gene id: 1765967:BW247_RS06650
uniprot id: A0A1P8UG75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1765967:BW247 RS06980
gene id: 1765967:BW247_RS06980
uniprot id: A0A1P8UG87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1765967:BW247 RS02235
gene id: 1765967:BW247_RS02235
uniprot id: A0A1P8UE42
names: Subunit
messages: Monomer.

1765967:BW247 RS02860
gene id: 1765967:BW247_RS02860
uniprot id: A0A1P8UEH9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1765967:BW247 RS04185
gene id: 1765967:BW247_RS04185
uniprot id: A0A1P8UF18
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS14085
gene id: 1765967:BW247_RS14085
uniprot id: A0A1P8UJU7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1765967:BW247 RS03500
gene id: 1765967:BW247_RS03500
uniprot id: A0A1P8UEL2
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS14055
gene id: 1765967:BW247_RS14055
uniprot id: A0A1P8UJS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1765967:BW247 RS00940
gene id: 1765967:BW247_RS00940
uniprot id: A0A1P8UDH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1765967:BW247 RS05745
gene id: 1765967:BW247_RS05745
uniprot id: A0A1P8UFN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1765967:BW247 RS10055
gene id: 1765967:BW247_RS10055
uniprot id: A0A1P8UHT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS07525
gene id: 1765967:BW247_RS07525
uniprot id: A0A1P8UGL7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1765967:BW247 RS12815
gene id: 1765967:BW247_RS12815
uniprot id: A0A1P8UJ69
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1765967:BW247 RS14225
gene id: 1765967:BW247_RS14225
uniprot id: A0A1P8UJT3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS13865
gene id: 1765967:BW247_RS13865
uniprot id: A0A1P8UJP5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1765967:BW247 RS05190
gene id: 1765967:BW247_RS05190
uniprot id: A0A1P8UFN7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1765967:BW247 RS13520
gene id: 1765967:BW247_RS13520
uniprot id: A0A1P8UJL7
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS01130
gene id: 1765967:BW247_RS01130
uniprot id: A0A1P8UDD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS10030
gene id: 1765967:BW247_RS10030
uniprot id: A0A1P8UHQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1765967:BW247 RS05770
gene id: 1765967:BW247_RS05770
uniprot id: A0A1P8UFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1765967:BW247 RS14435
gene id: 1765967:BW247_RS14435
uniprot id: A0A1P8UK43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS15660
gene id: 1765967:BW247_RS15660
uniprot id: A0A1P8UKL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1765967:BW247 RS09540
gene id: 1765967:BW247_RS09540
uniprot id: A0A1P8UHK9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1765967:BW247 RS13335
gene id: 1765967:BW247_RS13335
uniprot id: A0A1P8UJE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1765967:BW247 RS05520
gene id: 1765967:BW247_RS05520
uniprot id: A0A1P8UFK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1765967:BW247 RS11590
gene id: 1765967:BW247_RS11590
uniprot id: A0A1P8UIJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1765967:BW247 RS08900
gene id: 1765967:BW247_RS08900
uniprot id: A0A1P8UHD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1765967:BW247 RS10805
gene id: 1765967:BW247_RS10805
uniprot id: A0A1P8UI55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1765967:BW247 RS08130
gene id: 1765967:BW247_RS08130
uniprot id: A0A1P8UGV0
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1765967:BW247 RS11085
gene id: 1765967:BW247_RS11085
uniprot id: A0A1P8UI97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS00455
gene id: 1765967:BW247_RS00455
uniprot id: A0A1P8UD90
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1765967:BW247 RS06940
gene id: 1765967:BW247_RS06940
uniprot id: A0A1P8UG92
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS12595
gene id: 1765967:BW247_RS12595
uniprot id: A0A1P8UJ28
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1765967:BW247 RS09045
gene id: 1765967:BW247_RS09045
uniprot id: A0A1P8UHH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1765967:BW247 RS11290
gene id: 1765967:BW247_RS11290
uniprot id: A0A1P8UID3
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS15875
gene id: 1765967:BW247_RS15875
uniprot id: A0A1P8UKU1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1765967:BW247 RS06025
gene id: 1765967:BW247_RS06025
uniprot id: A0A1P8UL74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1765967:BW247 RS11640
gene id: 1765967:BW247_RS11640
uniprot id: A0A1P8UIK3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1765967:BW247 RS05855
gene id: 1765967:BW247_RS05855
uniprot id: A0A1P8UFT3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1765967:BW247 RS10340
gene id: 1765967:BW247_RS10340
uniprot id: A0A1P8UI08
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1765967:BW247 RS15120
gene id: 1765967:BW247_RS15120
uniprot id: A0A1P8UKB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1765967:BW247 RS12665
gene id: 1765967:BW247_RS12665
uniprot id: A0A1P8UJ45
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1765967:BW247 RS01640
gene id: 1765967:BW247_RS01640
uniprot id: A0A1P8UDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1765967:BW247 RS01795
gene id: 1765967:BW247_RS01795
uniprot id: A0A1P8UDR1
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1765967:BW247 RS14095
gene id: 1765967:BW247_RS14095
uniprot id: A0A1P8UJR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1765967:BW247 RS00225
gene id: 1765967:BW247_RS00225
uniprot id: A0A1P8UCZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1765967:BW247 RS10760
gene id: 1765967:BW247_RS10760
uniprot id: A0A1P8UI49
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1765967:BW247 RS01280
gene id: 1765967:BW247_RS01280
uniprot id: A0A1P8UDG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1765967:BW247 RS08185
gene id: 1765967:BW247_RS08185
uniprot id: A0A1P8UH10
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1765967:BW247 RS09815
gene id: 1765967:BW247_RS09815
uniprot id: A0A1P8UHP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS10245
gene id: 1765967:BW247_RS10245
uniprot id: A0A1P8UHV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1765967:BW247 RS00735
gene id: 1765967:BW247_RS00735
uniprot id: A0A1P8UD87
names: Similarity
messages: Belongs to the YjdM family.

1765967:BW247 RS11445
gene id: 1765967:BW247_RS11445
uniprot id: A0A1P8UIJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1765967:BW247 RS10370
gene id: 1765967:BW247_RS10370
uniprot id: A0A1P8UHX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1765967:BW247 RS06035
gene id: 1765967:BW247_RS06035
uniprot id: A0A1P8UFW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS04280
gene id: 1765967:BW247_RS04280
uniprot id: A0A1P8UEZ6
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS01405
gene id: 1765967:BW247_RS01405
uniprot id: A0A1P8UDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1765967:BW247 RS09130
gene id: 1765967:BW247_RS09130
uniprot id: A0A1P8UHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1765967:BW247 RS02330
gene id: 1765967:BW247_RS02330
uniprot id: A0A1P8UE45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1765967:BW247 RS01380
gene id: 1765967:BW247_RS01380
uniprot id: A0A1P8UDH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS09825
gene id: 1765967:BW247_RS09825
uniprot id: A0A1P8UHP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1765967:BW247 RS00720
gene id: 1765967:BW247_RS00720
uniprot id: A0A1P8UDA2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1765967:BW247 RS07170
gene id: 1765967:BW247_RS07170
uniprot id: A0A1P8UGD7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS02470
gene id: 1765967:BW247_RS02470
uniprot id: A0A1P8UE74
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS07745
gene id: 1765967:BW247_RS07745
uniprot id: A0A1P8UL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1765967:BW247 RS00865
gene id: 1765967:BW247_RS00865
uniprot id: A0A1P8UDF9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1765967:BW247 RS15680
gene id: 1765967:BW247_RS15680
uniprot id: A0A1P8UKJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1765967:BW247 RS04475
gene id: 1765967:BW247_RS04475
uniprot id: A0A1P8UF97
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS16000
gene id: 1765967:BW247_RS16000
uniprot id: A0A1P8UKM9
names: Similarity
messages: Belongs to the pirin family.

1765967:BW247 RS06885
gene id: 1765967:BW247_RS06885
uniprot id: A0A1P8UG73
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1765967:BW247 RS13675
gene id: 1765967:BW247_RS13675
uniprot id: A0A1P8UJK6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1765967:BW247 RS06020
gene id: 1765967:BW247_RS06020
uniprot id: A0A1P8UFU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1765967:BW247 RS09075
gene id: 1765967:BW247_RS09075
uniprot id: A0A1P8UHA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1765967:BW247 RS08905
gene id: 1765967:BW247_RS08905
uniprot id: A0A1P8UH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1765967:BW247 RS05375
gene id: 1765967:BW247_RS05375
uniprot id: A0A1P8UFH6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS05960
gene id: 1765967:BW247_RS05960
uniprot id: A0A1P8UFV8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1765967:BW247 RS04800
gene id: 1765967:BW247_RS04800
uniprot id: A0A1P8UFC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1765967:BW247 RS08310
gene id: 1765967:BW247_RS08310
uniprot id: A0A1P8UGY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Gfa family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.

1765967:BW247 RS09810
gene id: 1765967:BW247_RS09810
uniprot id: A0A1P8UHP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS13610
gene id: 1765967:BW247_RS13610
uniprot id: A0A1P8UJI6
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS07445
gene id: 1765967:BW247_RS07445
uniprot id: A0A1P8ULG7
names: Similarity
messages: Belongs to the TrpF family.

1765967:BW247 RS11220
gene id: 1765967:BW247_RS11220
uniprot id: A0A1P8UID6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1765967:BW247 RS10185
gene id: 1765967:BW247_RS10185
uniprot id: A0A1P8ULE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1765967:BW247 RS10960
gene id: 1765967:BW247_RS10960
uniprot id: A0A1P8UI71
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1765967:BW247 RS13040
gene id: 1765967:BW247_RS13040
uniprot id: A0A1P8UJ76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1765967:BW247 RS11965
gene id: 1765967:BW247_RS11965
uniprot id: A0A1P8UIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS16070
gene id: 1765967:BW247_RS16070
uniprot id: A0A1P8UKS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1765967:BW247 RS02290
gene id: 1765967:BW247_RS02290
uniprot id: A0A1P8UE19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1765967:BW247 RS09395
gene id: 1765967:BW247_RS09395
uniprot id: A0A1P8UHG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1765967:BW247 RS10355
gene id: 1765967:BW247_RS10355
uniprot id: A0A1P8UHZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1765967:BW247 RS14280
gene id: 1765967:BW247_RS14280
uniprot id: A0A1P8UJV7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1765967:BW247 RS04765
gene id: 1765967:BW247_RS04765
uniprot id: A0A1P8UFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1765967:BW247 RS07860
gene id: 1765967:BW247_RS07860
uniprot id: A0A1P8UGP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1765967:BW247 RS10530
gene id: 1765967:BW247_RS10530
uniprot id: A0A1P8UI19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1765967:BW247 RS03260
gene id: 1765967:BW247_RS03260
uniprot id: A0A1P8UEH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS09490
gene id: 1765967:BW247_RS09490
uniprot id: A0A1P8UHR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1765967:BW247 RS13340
gene id: 1765967:BW247_RS13340
uniprot id: A0A1P8UJH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1765967:BW247 RS14745
gene id: 1765967:BW247_RS14745
uniprot id: A0A1P8UK35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1765967:BW247 RS03405
gene id: 1765967:BW247_RS03405
uniprot id: A0A1P8UL98
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS01765
gene id: 1765967:BW247_RS01765
uniprot id: A0A1P8UDW2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1765967:BW247 RS08375
gene id: 1765967:BW247_RS08375
uniprot id: A0A1P8UH38
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1765967:BW247 RS05970
gene id: 1765967:BW247_RS05970
uniprot id: A0A1P8UFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS14140
gene id: 1765967:BW247_RS14140
uniprot id: A0A1P8UJU3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1765967:BW247 RS11630
gene id: 1765967:BW247_RS11630
uniprot id: A0A1P8UIJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1765967:BW247 RS07520
gene id: 1765967:BW247_RS07520
uniprot id: A0A1P8UGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1765967:BW247 RS12915
gene id: 1765967:BW247_RS12915
uniprot id: A0A1P8UJ59
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS14350
gene id: 1765967:BW247_RS14350
uniprot id: A0A1P8UJW1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1765967:BW247 RS13975
gene id: 1765967:BW247_RS13975
uniprot id: A0A1P8UJT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1765967:BW247 RS01465
gene id: 1765967:BW247_RS01465
uniprot id: A0A1P8UDP9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1765967:BW247 RS00230
gene id: 1765967:BW247_RS00230
uniprot id: A0A1P8UD51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS05840
gene id: 1765967:BW247_RS05840
uniprot id: A0A1P8UFS3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1765967:BW247 RS10640
gene id: 1765967:BW247_RS10640
uniprot id: A0A1P8UI35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1765967:BW247 RS01735
gene id: 1765967:BW247_RS01735
uniprot id: A0A1P8UDS7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1765967:BW247 RS02680
gene id: 1765967:BW247_RS02680
uniprot id: A0A1P8UE96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1765967:BW247 RS01290
gene id: 1765967:BW247_RS01290
uniprot id: A0A1P8UDP3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1765967:BW247 RS09325
gene id: 1765967:BW247_RS09325
uniprot id: A0A1P8UHF9
names: Subunit
messages: Homodimer.

1765967:BW247 RS13165
gene id: 1765967:BW247_RS13165
uniprot id: A0A1P8UJE5
names: Similarity
messages: Belongs to the WrbA family.

1765967:BW247 RS01055
gene id: 1765967:BW247_RS01055
uniprot id: A0A1P8UDL4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS03490
gene id: 1765967:BW247_RS03490
uniprot id: A0A1P8UER3
names: Similarity
messages: Belongs to the asparagine synthetase family.

1765967:BW247 RS14090
gene id: 1765967:BW247_RS14090
uniprot id: A0A1P8UJT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1765967:BW247 RS14025
gene id: 1765967:BW247_RS14025
uniprot id: A0A1P8ULL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1765967:BW247 RS07465
gene id: 1765967:BW247_RS07465
uniprot id: A0A1P8UGK8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1765967:BW247 RS04430
gene id: 1765967:BW247_RS04430
uniprot id: A0A1P8UF01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1765967:BW247 RS07425
gene id: 1765967:BW247_RS07425
uniprot id: A0A1P8UGH4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS15405
gene id: 1765967:BW247_RS15405
uniprot id: A0A1P8UKE6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1765967:BW247 RS09120
gene id: 1765967:BW247_RS09120
uniprot id: A0A1P8UH98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1765967:BW247 RS14275
gene id: 1765967:BW247_RS14275
uniprot id: A0A1P8UJW3
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1765967:BW247 RS11950
gene id: 1765967:BW247_RS11950
uniprot id: A0A1P8UIS8
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1765967:BW247 RS00045
gene id: 1765967:BW247_RS00045
uniprot id: A0A1P8UD54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1765967:BW247 RS06735
gene id: 1765967:BW247_RS06735
uniprot id: A0A1P8UG84
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1765967:BW247 RS08135
gene id: 1765967:BW247_RS08135
uniprot id: A0A1P8UGU2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1765967:BW247 RS11725
gene id: 1765967:BW247_RS11725
uniprot id: A0A1P8UIL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1765967:BW247 RS12200
gene id: 1765967:BW247_RS12200
uniprot id: A0A1P8UIW9
names: Similarity
messages: Belongs to the allantoicase family.

1765967:BW247 RS15800
gene id: 1765967:BW247_RS15800
uniprot id: A0A1P8ULR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1765967:BW247 RS01500
gene id: 1765967:BW247_RS01500
uniprot id: A0A1P8UDK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1765967:BW247 RS13755
gene id: 1765967:BW247_RS13755
uniprot id: A0A1P8UJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1765967:BW247 RS05555
gene id: 1765967:BW247_RS05555
uniprot id: A0A1P8UFM4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS14925
gene id: 1765967:BW247_RS14925
uniprot id: A0A1P8UK62
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1765967:BW247 RS08125
gene id: 1765967:BW247_RS08125
uniprot id: A0A1P8UH01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1765967:BW247 RS05815
gene id: 1765967:BW247_RS05815
uniprot id: A0A1P8UFP5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS05565
gene id: 1765967:BW247_RS05565
uniprot id: A0A1P8UFR3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1765967:BW247 RS00205
gene id: 1765967:BW247_RS00205
uniprot id: A0A1P8UD84
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1765967:BW247 RS15750
gene id: 1765967:BW247_RS15750
uniprot id: A0A1P8UKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1765967:BW247 RS11930
gene id: 1765967:BW247_RS11930
uniprot id: A0A1P8ULQ9
names: Similarity
messages: Belongs to the peptidase M24B family.

1765967:BW247 RS03250
gene id: 1765967:BW247_RS03250
uniprot id: A0A1P8UEK9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS03285
gene id: 1765967:BW247_RS03285
uniprot id: A0A1P8UEK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1765967:BW247 RS13990
gene id: 1765967:BW247_RS13990
uniprot id: A0A1P8UJP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1765967:BW247 RS09035
gene id: 1765967:BW247_RS09035
uniprot id: A0A1P8UHC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1765967:BW247 RS00350
gene id: 1765967:BW247_RS00350
uniprot id: A0A1P8UD30
names: Similarity
messages: Belongs to the UPF0178 family.

1765967:BW247 RS07700
gene id: 1765967:BW247_RS07700
uniprot id: A0A1P8UGN7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1765967:BW247 RS15235
gene id: 1765967:BW247_RS15235
uniprot id: A0A1P8UKB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS01285
gene id: 1765967:BW247_RS01285
uniprot id: A0A1P8UDN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1765967:BW247 RS03685
gene id: 1765967:BW247_RS03685
uniprot id: A0A1P8UER4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1765967:BW247 RS07515
gene id: 1765967:BW247_RS07515
uniprot id: A0A1P8UGH8
names: Similarity
messages: Belongs to the creatininase superfamily.

1765967:BW247 RS09505
gene id: 1765967:BW247_RS09505
uniprot id: A0A1P8UHQ0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS13725
gene id: 1765967:BW247_RS13725
uniprot id: A0A1P8UJL9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1765967:BW247 RS06600
gene id: 1765967:BW247_RS06600
uniprot id: A0A1P8UGA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS15735
gene id: 1765967:BW247_RS15735
uniprot id: A0A1P8UKL4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS07120
gene id: 1765967:BW247_RS07120
uniprot id: A0A1P8UGG3
names: Subcellular Location Annotation
messages: Cytoplasm

1765967:BW247 RS02250
gene id: 1765967:BW247_RS02250
uniprot id: A0A1P8UDX1
names: Similarity
messages: Belongs to the MipA/OmpV family.

1765967:BW247 RS15180
gene id: 1765967:BW247_RS15180
uniprot id: A0A1P8UKA6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1765967:BW247 RS06595
gene id: 1765967:BW247_RS06595
uniprot id: A0A1P8UG59
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1765967:BW247 RS02125
gene id: 1765967:BW247_RS02125
uniprot id: A0A1P8UDV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1765967:BW247 RS06365
gene id: 1765967:BW247_RS06365
uniprot id: A0A1P8UFY3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1765967:BW247 RS06900
gene id: 1765967:BW247_RS06900
uniprot id: A0A1P8UG88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1765967:BW247 RS12920
gene id: 1765967:BW247_RS12920
uniprot id: A0A1P8UJ93
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1765967:BW247 RS04820
gene id: 1765967:BW247_RS04820
uniprot id: A0A1P8UFG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1765967:BW247 RS10000
gene id: 1765967:BW247_RS10000
uniprot id: A0A1P8UHT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1765967:BW247 RS15635
gene id: 1765967:BW247_RS15635
uniprot id: A0A1P8UKH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1765967:BW247 RS14390
gene id: 1765967:BW247_RS14390
uniprot id: A0A1P8UK07
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1765967:BW247 RS02730
gene id: 1765967:BW247_RS02730
uniprot id: A0A1P8UE51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1765967:BW247 RS15685
gene id: 1765967:BW247_RS15685
uniprot id: A0A1P8UKK6
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS15070
gene id: 1765967:BW247_RS15070
uniprot id: A0A1P8UK79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1765967:BW247 RS02395
gene id: 1765967:BW247_RS02395
uniprot id: A0A1P8UE18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1765967:BW247 RS09370
gene id: 1765967:BW247_RS09370
uniprot id: A0A1P8UHF1
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1765967:BW247 RS08795
gene id: 1765967:BW247_RS08795
uniprot id: A0A1P8UH60
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS03530
gene id: 1765967:BW247_RS03530
uniprot id: A0A1P8UEJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1765967:BW247 RS01560
gene id: 1765967:BW247_RS01560
uniprot id: A0A1P8UDV3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1765967:BW247 RS00155
gene id: 1765967:BW247_RS00155
uniprot id: A0A1P8UKQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1765967:BW247 RS14030
gene id: 1765967:BW247_RS14030
uniprot id: A0A1P8UJU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1765967:BW247 RS02520
gene id: 1765967:BW247_RS02520
uniprot id: A0A1P8UE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS14255
gene id: 1765967:BW247_RS14255
uniprot id: A0A1P8UK16
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1765967:BW247 RS03330
gene id: 1765967:BW247_RS03330
uniprot id: A0A1P8UEG5
names: Similarity
messages: Belongs to the aspartokinase family.

1765967:BW247 RS09585
gene id: 1765967:BW247_RS09585
uniprot id: A0A1P8UHJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1765967:BW247 RS09010
gene id: 1765967:BW247_RS09010
uniprot id: A0A1P8UHG3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1765967:BW247 RS11625
gene id: 1765967:BW247_RS11625
uniprot id: A0A1P8UIL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS11235
gene id: 1765967:BW247_RS11235
uniprot id: A0A1P8UIC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1765967:BW247 RS12205
gene id: 1765967:BW247_RS12205
uniprot id: A0A1P8UIU2
names: Subunit
messages: Homodimer.

1765967:BW247 RS14525
gene id: 1765967:BW247_RS14525
uniprot id: A0A1P8UK03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1765967:BW247 RS03770
gene id: 1765967:BW247_RS03770
uniprot id: A0A1P8UEW4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1765967:BW247 RS07875
gene id: 1765967:BW247_RS07875
uniprot id: A0A1P8UGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1765967:BW247 RS06625
gene id: 1765967:BW247_RS06625
uniprot id: A0A1P8UG44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS02485
gene id: 1765967:BW247_RS02485
uniprot id: A0A1P8UE54
names: Similarity
messages: Belongs to the glutamine synthetase family.

1765967:BW247 RS14920
gene id: 1765967:BW247_RS14920
uniprot id: A0A1P8UK58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1765967:BW247 RS05785
gene id: 1765967:BW247_RS05785
uniprot id: A0A1P8UFY8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1765967:BW247 RS03400
gene id: 1765967:BW247_RS03400
uniprot id: A0A1P8UEP8
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS10345
gene id: 1765967:BW247_RS10345
uniprot id: A0A1P8UHV9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1765967:BW247 RS15415
gene id: 1765967:BW247_RS15415
uniprot id: A0A1P8UKF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1765967:BW247 RS09425
gene id: 1765967:BW247_RS09425
uniprot id: A0A1P8UHF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS03210
gene id: 1765967:BW247_RS03210
uniprot id: A0A1P8UEE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1765967:BW247 RS03380
gene id: 1765967:BW247_RS03380
uniprot id: A0A1P8UEJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS07890
gene id: 1765967:BW247_RS07890
uniprot id: A0A1P8UGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1765967:BW247 RS03175
gene id: 1765967:BW247_RS03175
uniprot id: A0A1P8UEE2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS11030
gene id: 1765967:BW247_RS11030
uniprot id: A0A1P8UI87
names: Similarity
messages: Belongs to the UPF0235 family.

1765967:BW247 RS00240
gene id: 1765967:BW247_RS00240
uniprot id: A0A1P8UD02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1765967:BW247 RS12890
gene id: 1765967:BW247_RS12890
uniprot id: A0A1P8UJA1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS00680
gene id: 1765967:BW247_RS00680
uniprot id: A0A1P8UD45
names: Similarity
messages: Belongs to the peptidase C56 family.

1765967:BW247 RS07050
gene id: 1765967:BW247_RS07050
uniprot id: A0A1P8UGD1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1765967:BW247 RS05290
gene id: 1765967:BW247_RS05290
uniprot id: A0A1P8UFG4
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

1765967:BW247 RS11405
gene id: 1765967:BW247_RS11405
uniprot id: A0A1P8UIF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1765967:BW247 RS06170
gene id: 1765967:BW247_RS06170
uniprot id: A0A1P8UFV5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS06325
gene id: 1765967:BW247_RS06325
uniprot id: A0A1P8UG13
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1765967:BW247 RS09240
gene id: 1765967:BW247_RS09240
uniprot id: A0A1P8UHD1
names: Similarity
messages: Belongs to the UPF0145 family.

1765967:BW247 RS14035
gene id: 1765967:BW247_RS14035
uniprot id: A0A1P8UJU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1765967:BW247 RS15175
gene id: 1765967:BW247_RS15175
uniprot id: A0A1P8UK97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1765967:BW247 RS02535
gene id: 1765967:BW247_RS02535
uniprot id: A0A1P8UE89
names: Similarity
messages: Belongs to the peptidase S66 family.

1765967:BW247 RS13850
gene id: 1765967:BW247_RS13850
uniprot id: A0A1P8UJN6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1765967:BW247 RS02410
gene id: 1765967:BW247_RS02410
uniprot id: A0A1P8UE68
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS09450
gene id: 1765967:BW247_RS09450
uniprot id: A0A1P8UHH8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS05105
gene id: 1765967:BW247_RS05105
uniprot id: A0A1P8UFC5
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1765967:BW247 RS14735
gene id: 1765967:BW247_RS14735
uniprot id: A0A1P8UK28
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1765967:BW247 RS07740
gene id: 1765967:BW247_RS07740
uniprot id: A0A1P8UGM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1765967:BW247 RS03580
gene id: 1765967:BW247_RS03580
uniprot id: A0A1P8UEK0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1765967:BW247 RS14300
gene id: 1765967:BW247_RS14300
uniprot id: A0A1P8UJU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1765967:BW247 RS03970
gene id: 1765967:BW247_RS03970
uniprot id: A0A1P8UEU6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1765967:BW247 RS08955
gene id: 1765967:BW247_RS08955
uniprot id: A0A1P8UHE9
names: Similarity
messages: Belongs to the peptidase S24 family.

1765967:BW247 RS13045
gene id: 1765967:BW247_RS13045
uniprot id: A0A1P8UJC5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1765967:BW247 RS07000
gene id: 1765967:BW247_RS07000
uniprot id: A0A1P8ULB1
names: Similarity
messages: Belongs to the YciI family.

1765967:BW247 RS04040
gene id: 1765967:BW247_RS04040
uniprot id: A0A1P8UET3
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS04595
gene id: 1765967:BW247_RS04595
uniprot id: A0A1P8UL21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1765967:BW247 RS09085
gene id: 1765967:BW247_RS09085
uniprot id: A0A1P8UHC7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1765967:BW247 RS04080
gene id: 1765967:BW247_RS04080
uniprot id: A0A1P8UEW3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1765967:BW247 RS15265
gene id: 1765967:BW247_RS15265
uniprot id: A0A1P8UKI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS04350
gene id: 1765967:BW247_RS04350
uniprot id: A0A1P8UF68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1765967:BW247 RS03535
gene id: 1765967:BW247_RS03535
uniprot id: A0A1P8UEN5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1765967:BW247 RS11450
gene id: 1765967:BW247_RS11450
uniprot id: A0A1P8UIG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1765967:BW247 RS10480
gene id: 1765967:BW247_RS10480
uniprot id: A0A1P8UHZ6
names: Similarity
messages: Belongs to the RecJ family.

1765967:BW247 RS14100
gene id: 1765967:BW247_RS14100
uniprot id: A0A1P8UJR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1765967:BW247 RS02055
gene id: 1765967:BW247_RS02055
uniprot id: A0A1P8UDY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1765967:BW247 RS06605
gene id: 1765967:BW247_RS06605
uniprot id: A0A1P8UG33
names: Similarity
messages: Belongs to the thioredoxin family.

1765967:BW247 RS04205
gene id: 1765967:BW247_RS04205
uniprot id: A0A1P8UEW5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1765967:BW247 RS03000
gene id: 1765967:BW247_RS03000
uniprot id: A0A1P8UEB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1765967:BW247 RS12040
gene id: 1765967:BW247_RS12040
uniprot id: A0A1P8UIS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1765967:BW247 RS07730
gene id: 1765967:BW247_RS07730
uniprot id: A0A1P8UGN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1765967:BW247 RS03100
gene id: 1765967:BW247_RS03100
uniprot id: A0A1P8UEL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS04170
gene id: 1765967:BW247_RS04170
uniprot id: A0A1P8UEX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1765967:BW247 RS00595
gene id: 1765967:BW247_RS00595
uniprot id: A0A1P8UDB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1765967:BW247 RS07950
gene id: 1765967:BW247_RS07950
uniprot id: A0A1P8UGZ3
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1765967:BW247 RS15985
gene id: 1765967:BW247_RS15985
uniprot id: A0A1P8UKR7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1765967:BW247 RS03370
gene id: 1765967:BW247_RS03370
uniprot id: A0A1P8UEM7
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1765967:BW247 RS12820
gene id: 1765967:BW247_RS12820
uniprot id: A0A1P8UJA4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1765967:BW247 RS02000
gene id: 1765967:BW247_RS02000
uniprot id: A0A1P8UDT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1765967:BW247 RS09260
gene id: 1765967:BW247_RS09260
uniprot id: A0A1P8UHD6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1765967:BW247 RS09365
gene id: 1765967:BW247_RS09365
uniprot id: A0A1P8UHI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1765967:BW247 RS15190
gene id: 1765967:BW247_RS15190
uniprot id: A0A1P8UKA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1765967:BW247 RS13220
gene id: 1765967:BW247_RS13220
uniprot id: A0A1P8UJF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1765967:BW247 RS15940
gene id: 1765967:BW247_RS15940
uniprot id: A0A1P8UKM4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS07475
gene id: 1765967:BW247_RS07475
uniprot id: A0A1P8UGP7
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS10930
gene id: 1765967:BW247_RS10930
uniprot id: A0A1P8UI86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS03320
gene id: 1765967:BW247_RS03320
uniprot id: A0A1P8UEI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1765967:BW247 RS01355
gene id: 1765967:BW247_RS01355
uniprot id: A0A1P8UL43
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1765967:BW247 RS16095
gene id: 1765967:BW247_RS16095
uniprot id: A0A1P8UKZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1765967:BW247 RS06635
gene id: 1765967:BW247_RS06635
uniprot id: A0A1P8ULF3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1765967:BW247 RS03335
gene id: 1765967:BW247_RS03335
uniprot id: A0A1P8UEG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1765967:BW247 RS09090
gene id: 1765967:BW247_RS09090
uniprot id: A0A1P8UHA7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1765967:BW247 RS06630
gene id: 1765967:BW247_RS06630
uniprot id: A0A1P8UG23
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1765967:BW247 RS16105
gene id: 1765967:BW247_RS16105
uniprot id: A0A1P8UKQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1765967:BW247 RS13800
gene id: 1765967:BW247_RS13800
uniprot id: A0A1P8UJN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1765967:BW247 RS00555
gene id: 1765967:BW247_RS00555
uniprot id: A0A1P8UD60
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1765967:BW247 RS10415
gene id: 1765967:BW247_RS10415
uniprot id: A0A1P8UHZ5
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1765967:BW247 RS14135
gene id: 1765967:BW247_RS14135
uniprot id: A0A1P8UJV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1765967:BW247 RS02735
gene id: 1765967:BW247_RS02735
uniprot id: A0A1P8UE58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1765967:BW247 RS16075
gene id: 1765967:BW247_RS16075
uniprot id: A0A1P8UKR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1765967:BW247 RS14285
gene id: 1765967:BW247_RS14285
uniprot id: A0A1P8UJT8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1765967:BW247 RS14070
gene id: 1765967:BW247_RS14070
uniprot id: A0A1P8UJZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1765967:BW247 RS07705
gene id: 1765967:BW247_RS07705
uniprot id: A0A1P8UGL8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1765967:BW247 RS15315
gene id: 1765967:BW247_RS15315
uniprot id: A0A1P8UKC9
names: Similarity
messages: Belongs to the GSP E family.

1765967:BW247 RS12780
gene id: 1765967:BW247_RS12780
uniprot id: A0A1P8UJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1765967:BW247 RS15150
gene id: 1765967:BW247_RS15150
uniprot id: A0A1P8UKA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS08150
gene id: 1765967:BW247_RS08150
uniprot id: A0A1P8ULB7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1765967:BW247 RS04425
gene id: 1765967:BW247_RS04425
uniprot id: A0A1P8UF33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1765967:BW247 RS10495
gene id: 1765967:BW247_RS10495
uniprot id: A0A1P8UHY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS14355
gene id: 1765967:BW247_RS14355
uniprot id: A0A1P8UJV4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1765967:BW247 RS01540
gene id: 1765967:BW247_RS01540
uniprot id: A0A1P8UDM0
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 2 family.

1765967:BW247 RS13875
gene id: 1765967:BW247_RS13875
uniprot id: A0A1P8UJN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1765967:BW247 RS06320
gene id: 1765967:BW247_RS06320
uniprot id: A0A1P8UG69
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1765967:BW247 RS07300
gene id: 1765967:BW247_RS07300
uniprot id: A0A1P8UGL0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1765967:BW247 RS00890
gene id: 1765967:BW247_RS00890
uniprot id: A0A1P8UKV5
names: Function
names: Subunit
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

1765967:BW247 RS01600
gene id: 1765967:BW247_RS01600
uniprot id: A0A1P8UDM4
names: Similarity
messages: Belongs to the histone deacetylase family.

1765967:BW247 RS02650
gene id: 1765967:BW247_RS02650
uniprot id: A0A1P8UE38
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1765967:BW247 RS02355
gene id: 1765967:BW247_RS02355
uniprot id: A0A1P8UKX2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1765967:BW247 RS00565
gene id: 1765967:BW247_RS00565
uniprot id: A0A1P8UD35
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1765967:BW247 RS11460
gene id: 1765967:BW247_RS11460
uniprot id: A0A1P8UII7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1765967:BW247 RS00390
gene id: 1765967:BW247_RS00390
uniprot id: A0A1P8UKS7
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1765967:BW247 RS00105
gene id: 1765967:BW247_RS00105
uniprot id: A0A1P8UCW7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS01450
gene id: 1765967:BW247_RS01450
uniprot id: A0A1P8UDT1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1765967:BW247 RS13845
gene id: 1765967:BW247_RS13845
uniprot id: A0A1P8UJV2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1765967:BW247 RS08100
gene id: 1765967:BW247_RS08100
uniprot id: A0A1P8UGT6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1765967:BW247 RS12610
gene id: 1765967:BW247_RS12610
uniprot id: A0A1P8UJ08
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS11840
gene id: 1765967:BW247_RS11840
uniprot id: A0A1P8UIN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS14715
gene id: 1765967:BW247_RS14715
uniprot id: A0A1P8UK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS01205
gene id: 1765967:BW247_RS01205
uniprot id: A0A1P8UDG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1765967:BW247 RS10290
gene id: 1765967:BW247_RS10290
uniprot id: A0A1P8UHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1765967:BW247 RS09275
gene id: 1765967:BW247_RS09275
uniprot id: A0A1P8UHG1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1765967:BW247 RS12930
gene id: 1765967:BW247_RS12930
uniprot id: A0A1P8UJ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1765967:BW247 RS13625
gene id: 1765967:BW247_RS13625
uniprot id: A0A1P8UJK3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1765967:BW247 RS12490
gene id: 1765967:BW247_RS12490
uniprot id: A0A1P8UJ07
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1765967:BW247 RS14130
gene id: 1765967:BW247_RS14130
uniprot id: A0A1P8UJX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1765967:BW247 RS13590
gene id: 1765967:BW247_RS13590
uniprot id: A0A1P8UJM9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1765967:BW247 RS09455
gene id: 1765967:BW247_RS09455
uniprot id: A0A1P8UHP0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS12340
gene id: 1765967:BW247_RS12340
uniprot id: A0A1P8UIV4
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1765967:BW247 RS02750
gene id: 1765967:BW247_RS02750
uniprot id: A0A1P8UEF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1765967:BW247 RS07285
gene id: 1765967:BW247_RS07285
uniprot id: A0A1P8UGD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1765967:BW247 RS13980
gene id: 1765967:BW247_RS13980
uniprot id: A0A1P8UJN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1765967:BW247 RS12245
gene id: 1765967:BW247_RS12245
uniprot id: A0A1P8UIV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1765967:BW247 RS06330
gene id: 1765967:BW247_RS06330
uniprot id: A0A1P8UFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1765967:BW247 RS04520
gene id: 1765967:BW247_RS04520
uniprot id: A0A1P8UF27
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS01505
gene id: 1765967:BW247_RS01505
uniprot id: A0A1P8UDP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1765967:BW247 RS09245
gene id: 1765967:BW247_RS09245
uniprot id: A0A1P8UHD5
names: Similarity
messages: Belongs to the UPF0145 family.

1765967:BW247 RS08280
gene id: 1765967:BW247_RS08280
uniprot id: A0A1P8UGW4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS12950
gene id: 1765967:BW247_RS12950
uniprot id: A0A1P8UJ66
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1765967:BW247 RS06645
gene id: 1765967:BW247_RS06645
uniprot id: A0A1P8UG53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1765967:BW247 RS11165
gene id: 1765967:BW247_RS11165
uniprot id: A0A1P8UIC1
names: Similarity
messages: Belongs to the glutamate synthase family.

1765967:BW247 RS14505
gene id: 1765967:BW247_RS14505
uniprot id: A0A1P8UK27
names: Subcellular Location Annotation
messages: Cytoplasm

1765967:BW247 RS04000
gene id: 1765967:BW247_RS04000
uniprot id: A0A1P8UEW7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1765967:BW247 RS14855
gene id: 1765967:BW247_RS14855
uniprot id: A0A1P8UK49
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1765967:BW247 RS13665
gene id: 1765967:BW247_RS13665
uniprot id: A0A1P8UJJ6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1765967:BW247 RS03315
gene id: 1765967:BW247_RS03315
uniprot id: A0A1P8UL03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1765967:BW247 RS14000
gene id: 1765967:BW247_RS14000
uniprot id: A0A1P8UJR0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1765967:BW247 RS12510
gene id: 1765967:BW247_RS12510
uniprot id: A0A1P8UJ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

1765967:BW247 RS09110
gene id: 1765967:BW247_RS09110
uniprot id: A0A1P8UHI0
names: Similarity
messages: Belongs to the skp family.

1765967:BW247 RS09190
gene id: 1765967:BW247_RS09190
uniprot id: A0A1P8UHC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1765967:BW247 RS02925
gene id: 1765967:BW247_RS02925
uniprot id: A0A1P8UEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS08345
gene id: 1765967:BW247_RS08345
uniprot id: A0A1P8UGY5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1765967:BW247 RS13955
gene id: 1765967:BW247_RS13955
uniprot id: A0A1P8UJR2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1765967:BW247 RS14360
gene id: 1765967:BW247_RS14360
uniprot id: A0A1P8UJU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1765967:BW247 RS15965
gene id: 1765967:BW247_RS15965
uniprot id: A0A1P8UKN5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1765967:BW247 RS13210
gene id: 1765967:BW247_RS13210
uniprot id: A0A1P8UJF1
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS11685
gene id: 1765967:BW247_RS11685
uniprot id: A0A1P8UIL1
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1765967:BW247 RS00120
gene id: 1765967:BW247_RS00120
uniprot id: A0A1P8UD39
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1765967:BW247 RS09145
gene id: 1765967:BW247_RS09145
uniprot id: A0A1P8UHB6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS02545
gene id: 1765967:BW247_RS02545
uniprot id: A0A1P8UE21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1765967:BW247 RS14370
gene id: 1765967:BW247_RS14370
uniprot id: A0A1P8UJW9
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS16155
gene id: 1765967:BW247_RS16155
uniprot id: A0A1P8UL05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1765967:BW247 RS06820
gene id: 1765967:BW247_RS06820
uniprot id: A0A1P8UGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1765967:BW247 RS07695
gene id: 1765967:BW247_RS07695
uniprot id: A0A1P8UGT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1765967:BW247 RS15220
gene id: 1765967:BW247_RS15220
uniprot id: A0A1P8UKD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1765967:BW247 RS13515
gene id: 1765967:BW247_RS13515
uniprot id: A0A1P8UJH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 100 family.

1765967:BW247 RS05835
gene id: 1765967:BW247_RS05835
uniprot id: A0A1P8UFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS05695
gene id: 1765967:BW247_RS05695
uniprot id: A0A1P8UFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1765967:BW247 RS15785
gene id: 1765967:BW247_RS15785
uniprot id: A0A1P8UKJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1765967:BW247 RS01960
gene id: 1765967:BW247_RS01960
uniprot id: A0A1P8UDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1765967:BW247 RS04370
gene id: 1765967:BW247_RS04370
uniprot id: A0A1P8UEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS02610
gene id: 1765967:BW247_RS02610
uniprot id: A0A1P8UED4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1765967:BW247 RS06880
gene id: 1765967:BW247_RS06880
uniprot id: A0A1P8UG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1765967:BW247 RS07670
gene id: 1765967:BW247_RS07670
uniprot id: A0A1P8UGM5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1765967:BW247 RS06460
gene id: 1765967:BW247_RS06460
uniprot id: A0A1P8UFZ6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1765967:BW247 RS11620
gene id: 1765967:BW247_RS11620
uniprot id: A0A1P8UIJ5
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1765967:BW247 RS14710
gene id: 1765967:BW247_RS14710
uniprot id: A0A1P8UK19
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1765967:BW247 RS01940
gene id: 1765967:BW247_RS01940
uniprot id: A0A1P8UDZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1765967:BW247 RS00955
gene id: 1765967:BW247_RS00955
uniprot id: A0A1P8UDJ7
names: Similarity
messages: Belongs to the TrpC family.

1765967:BW247 RS14250
gene id: 1765967:BW247_RS14250
uniprot id: A0A1P8UJW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1765967:BW247 RS15310
gene id: 1765967:BW247_RS15310
uniprot id: A0A1P8UKD3
names: Similarity
messages: Belongs to the GSP E family.

1765967:BW247 RS16065
gene id: 1765967:BW247_RS16065
uniprot id: A0A1P8UKQ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS11075
gene id: 1765967:BW247_RS11075
uniprot id: A0A1P8UI91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1765967:BW247 RS02350
gene id: 1765967:BW247_RS02350
uniprot id: A0A1P8UE29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1765967:BW247 RS07930
gene id: 1765967:BW247_RS07930
uniprot id: A0A1P8UGU7
names: Similarity
messages: Belongs to the type III secretion exporter family.

1765967:BW247 RS12185
gene id: 1765967:BW247_RS12185
uniprot id: A0A1P8UIZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS03265
gene id: 1765967:BW247_RS03265
uniprot id: A0A1P8UEF3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1765967:BW247 RS06670
gene id: 1765967:BW247_RS06670
uniprot id: A0A1P8UGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1765967:BW247 RS00345
gene id: 1765967:BW247_RS00345
uniprot id: A0A1P8UD99
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1765967:BW247 RS15210
gene id: 1765967:BW247_RS15210
uniprot id: A0A1P8UKB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1765967:BW247 RS07955
gene id: 1765967:BW247_RS07955
uniprot id: A0A1P8UGS7
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1765967:BW247 RS07685
gene id: 1765967:BW247_RS07685
uniprot id: A0A1P8UGP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1765967:BW247 RS03255
gene id: 1765967:BW247_RS03255
uniprot id: A0A1P8UEH6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1765967:BW247 RS08005
gene id: 1765967:BW247_RS08005
uniprot id: A0A1P8UGR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS02365
gene id: 1765967:BW247_RS02365
uniprot id: A0A1P8UDZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1765967:BW247 RS02105
gene id: 1765967:BW247_RS02105
uniprot id: A0A1P8UE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS08260
gene id: 1765967:BW247_RS08260
uniprot id: A0A1P8UGX0
names: Similarity
messages: Belongs to the FrhG family.

1765967:BW247 RS10755
gene id: 1765967:BW247_RS10755
uniprot id: A0A1P8UI59
names: Similarity
messages: Belongs to the CsoS2 family.

1765967:BW247 RS09205
gene id: 1765967:BW247_RS09205
uniprot id: A0A1P8UHC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1765967:BW247 RS09025
gene id: 1765967:BW247_RS09025
uniprot id: A0A1P8UHB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1765967:BW247 RS13660
gene id: 1765967:BW247_RS13660
uniprot id: A0A1P8UJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS08335
gene id: 1765967:BW247_RS08335
uniprot id: A0A1P8UGY1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1765967:BW247 RS05765
gene id: 1765967:BW247_RS05765
uniprot id: A0A1P8UFQ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1765967:BW247 RS07485
gene id: 1765967:BW247_RS07485
uniprot id: A0A1P8UGI1
names: Similarity
messages: Belongs to the YkuD family.

1765967:BW247 RS12505
gene id: 1765967:BW247_RS12505
uniprot id: A0A1P8UIY7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1765967:BW247 RS07015
gene id: 1765967:BW247_RS07015
uniprot id: A0A1P8UGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS07910
gene id: 1765967:BW247_RS07910
uniprot id: A0A1P8UGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1765967:BW247 RS00635
gene id: 1765967:BW247_RS00635
uniprot id: A0A1P8UDB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1765967:BW247 RS12860
gene id: 1765967:BW247_RS12860
uniprot id: A0A1P8UJ55
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1765967:BW247 RS00170
gene id: 1765967:BW247_RS00170
uniprot id: A0A1P8UCY2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1765967:BW247 RS00355
gene id: 1765967:BW247_RS00355
uniprot id: A0A1P8UD05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1765967:BW247 RS00250
gene id: 1765967:BW247_RS00250
uniprot id: A0A1P8UCZ2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1765967:BW247 RS11475
gene id: 1765967:BW247_RS11475
uniprot id: A0A1P8UIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1765967:BW247 RS08120
gene id: 1765967:BW247_RS08120
uniprot id: A0A1P8UGX2
names: Similarity
messages: Belongs to the HesB/IscA family.

1765967:BW247 RS04150
gene id: 1765967:BW247_RS04150
uniprot id: A0A1P8UEV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1765967:BW247 RS11780
gene id: 1765967:BW247_RS11780
uniprot id: A0A1P8UIL6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1765967:BW247 RS06380
gene id: 1765967:BW247_RS06380
uniprot id: A0A1P8UG09
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1765967:BW247 RS01970
gene id: 1765967:BW247_RS01970
uniprot id: A0A1P8UDT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1765967:BW247 RS10040
gene id: 1765967:BW247_RS10040
uniprot id: A0A1P8UHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1765967:BW247 RS09560
gene id: 1765967:BW247_RS09560
uniprot id: A0A1P8UHQ6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1765967:BW247 RS10490
gene id: 1765967:BW247_RS10490
uniprot id: A0A1P8UI03
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1765967:BW247 RS02430
gene id: 1765967:BW247_RS02430
uniprot id: A0A1P8UE00
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1765967:BW247 RS09210
gene id: 1765967:BW247_RS09210
uniprot id: A0A1P8UHE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1765967:BW247 RS10235
gene id: 1765967:BW247_RS10235
uniprot id: A0A1P8UI37
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1765967:BW247 RS11535
gene id: 1765967:BW247_RS11535
uniprot id: A0A1P8UII4
names: Similarity
messages: Belongs to the citrate synthase family.

1765967:BW247 RS15395
gene id: 1765967:BW247_RS15395
uniprot id: A0A1P8UKD1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1765967:BW247 RS00800
gene id: 1765967:BW247_RS00800
uniprot id: A0A1P8UD65
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS13485
gene id: 1765967:BW247_RS13485
uniprot id: A0A1P8UJG3
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1765967:BW247 RS10970
gene id: 1765967:BW247_RS10970
uniprot id: A0A1P8UI75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1765967:BW247 RS03565
gene id: 1765967:BW247_RS03565
uniprot id: A0A1P8UEM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1765967:BW247 RS00505
gene id: 1765967:BW247_RS00505
uniprot id: A0A1P8UD49
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1765967:BW247 RS02230
gene id: 1765967:BW247_RS02230
uniprot id: A0A1P8UE46
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS12805
gene id: 1765967:BW247_RS12805
uniprot id: A0A1P8UJ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1765967:BW247 RS11160
gene id: 1765967:BW247_RS11160
uniprot id: A0A1P8UIB4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1765967:BW247 RS13270
gene id: 1765967:BW247_RS13270
uniprot id: A0A1P8UJH8
names: Subcellular Location Annotation
messages: Cytoplasm

1765967:BW247 RS13960
gene id: 1765967:BW247_RS13960
uniprot id: A0A1P8UJS1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1765967:BW247 RS02945
gene id: 1765967:BW247_RS02945
uniprot id: A0A1P8UEA6
names: Similarity
messages: Belongs to the HSP15 family.

1765967:BW247 RS10035
gene id: 1765967:BW247_RS10035
uniprot id: A0A1P8UHR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1765967:BW247 RS14565
gene id: 1765967:BW247_RS14565
uniprot id: A0A1P8UJZ7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1765967:BW247 RS15275
gene id: 1765967:BW247_RS15275
uniprot id: A0A1P8UKC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1765967:BW247 RS01430
gene id: 1765967:BW247_RS01430
uniprot id: A0A1P8UDK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1765967:BW247 RS04805
gene id: 1765967:BW247_RS04805
uniprot id: A0A1P8UF63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS02375
gene id: 1765967:BW247_RS02375
uniprot id: A0A1P8UE31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS10430
gene id: 1765967:BW247_RS10430
uniprot id: A0A1P8UI62
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1765967:BW247 RS11130
gene id: 1765967:BW247_RS11130
uniprot id: A0A1P8UIA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1765967:BW247 RS03070
gene id: 1765967:BW247_RS03070
uniprot id: A0A1P8UEH5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS03280
gene id: 1765967:BW247_RS03280
uniprot id: A0A1P8UEF6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1765967:BW247 RS14270
gene id: 1765967:BW247_RS14270
uniprot id: A0A1P8UJY5
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1765967:BW247 RS15325
gene id: 1765967:BW247_RS15325
uniprot id: A0A1P8UKD9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1765967:BW247 RS03510
gene id: 1765967:BW247_RS03510
uniprot id: A0A1P8UEJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1765967:BW247 RS11255
gene id: 1765967:BW247_RS11255
uniprot id: A0A1P8UIG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1765967:BW247 RS10630
gene id: 1765967:BW247_RS10630
uniprot id: A0A1P8UI36
names: Similarity
messages: Belongs to the asparagine synthetase family.

1765967:BW247 RS11605
gene id: 1765967:BW247_RS11605
uniprot id: A0A1P8UIJ1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1765967:BW247 RS13305
gene id: 1765967:BW247_RS13305
uniprot id: A0A1P8UJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1765967:BW247 RS15105
gene id: 1765967:BW247_RS15105
uniprot id: A0A1P8UKF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1765967:BW247 RS14125
gene id: 1765967:BW247_RS14125
uniprot id: A0A1P8UJS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1765967:BW247 RS07380
gene id: 1765967:BW247_RS07380
uniprot id: A0A1P8UGG4
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1765967:BW247 RS12670
gene id: 1765967:BW247_RS12670
uniprot id: A0A1P8UJ27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1765967:BW247 RS01670
gene id: 1765967:BW247_RS01670
uniprot id: A0A1P8UDR3
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS13855
gene id: 1765967:BW247_RS13855
uniprot id: A0A1P8UJR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1765967:BW247 RS09030
gene id: 1765967:BW247_RS09030
uniprot id: A0A1P8UH99
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1765967:BW247 RS02185
gene id: 1765967:BW247_RS02185
uniprot id: A0A1P8UDW0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1765967:BW247 RS06715
gene id: 1765967:BW247_RS06715
uniprot id: A0A1P8UGB9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1765967:BW247 RS13705
gene id: 1765967:BW247_RS13705
uniprot id: A0A1P8UJK9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1765967:BW247 RS06705
gene id: 1765967:BW247_RS06705
uniprot id: A0A1P8UG62
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1765967:BW247 RS06370
gene id: 1765967:BW247_RS06370
uniprot id: A0A1P8UG81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1765967:BW247 RS15270
gene id: 1765967:BW247_RS15270
uniprot id: A0A1P8ULP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS11900
gene id: 1765967:BW247_RS11900
uniprot id: A0A1P8UIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1765967:BW247 RS03890
gene id: 1765967:BW247_RS03890
uniprot id: A0A1P8UER6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1765967:BW247 RS07645
gene id: 1765967:BW247_RS07645
uniprot id: A0A1P8UGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1765967:BW247 RS03895
gene id: 1765967:BW247_RS03895
uniprot id: A0A1P8UEX9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1765967:BW247 RS03880
gene id: 1765967:BW247_RS03880
uniprot id: A0A1P8UES0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1765967:BW247 RS14240
gene id: 1765967:BW247_RS14240
uniprot id: A0A1P8UJV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS14020
gene id: 1765967:BW247_RS14020
uniprot id: A0A1P8UJQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1765967:BW247 RS08460
gene id: 1765967:BW247_RS08460
uniprot id: A0A1P8UH62
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1765967:BW247 RS10965
gene id: 1765967:BW247_RS10965
uniprot id: A0A1P8UIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1765967:BW247 RS14080
gene id: 1765967:BW247_RS14080
uniprot id: A0A1P8UJW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1765967:BW247 RS14145
gene id: 1765967:BW247_RS14145
uniprot id: A0A1P8UJS2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1765967:BW247 RS07840
gene id: 1765967:BW247_RS07840
uniprot id: A0A1P8UGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1765967:BW247 RS12540
gene id: 1765967:BW247_RS12540
uniprot id: A0A1P8UJ18
names: Similarity
messages: Belongs to the asparagine synthetase family.

1765967:BW247 RS12825
gene id: 1765967:BW247_RS12825
uniprot id: A0A1P8UJ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS05920
gene id: 1765967:BW247_RS05920
uniprot id: A0A1P8UG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1765967:BW247 RS12480
gene id: 1765967:BW247_RS12480
uniprot id: A0A1P8UJ43
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1765967:BW247 RS15710
gene id: 1765967:BW247_RS15710
uniprot id: A0A1P8UKP3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1765967:BW247 RS10605
gene id: 1765967:BW247_RS10605
uniprot id: A0A1P8UI70
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS04160
gene id: 1765967:BW247_RS04160
uniprot id: A0A1P8UEV1
names: Similarity
messages: Belongs to the thioredoxin family.

1765967:BW247 RS03365
gene id: 1765967:BW247_RS03365
uniprot id: A0A1P8UEP5
names: Function
names: Similarity
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.

1765967:BW247 RS11170
gene id: 1765967:BW247_RS11170
uniprot id: A0A1P8UIB2
names: Similarity
messages: Belongs to the TPP enzyme family.

1765967:BW247 RS15460
gene id: 1765967:BW247_RS15460
uniprot id: A0A1P8UKF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS08400
gene id: 1765967:BW247_RS08400
uniprot id: A0A1P8ULC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1765967:BW247 RS04180
gene id: 1765967:BW247_RS04180
uniprot id: A0A1P8UEV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1765967:BW247 RS14075
gene id: 1765967:BW247_RS14075
uniprot id: A0A1P8UJR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1765967:BW247 RS01900
gene id: 1765967:BW247_RS01900
uniprot id: A0A1P8UE14
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1765967:BW247 RS05140
gene id: 1765967:BW247_RS05140
uniprot id: A0A1P8UFM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1765967:BW247 RS13315
gene id: 1765967:BW247_RS13315
uniprot id: A0A1P8UJC3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1765967:BW247 RS04100
gene id: 1765967:BW247_RS04100
uniprot id: A0A1P8UEU3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS03550
gene id: 1765967:BW247_RS03550
uniprot id: A0A1P8UL30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1765967:BW247 RS13200
gene id: 1765967:BW247_RS13200
uniprot id: A0A1P8UJB0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1765967:BW247 RS08115
gene id: 1765967:BW247_RS08115
uniprot id: A0A1P8UGW1
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1765967:BW247 RS09835
gene id: 1765967:BW247_RS09835
uniprot id: A0A1P8UHT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS11040
gene id: 1765967:BW247_RS11040
uniprot id: A0A1P8UIB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1765967:BW247 RS07115
gene id: 1765967:BW247_RS07115
uniprot id: A0A1P8UGD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS02215
gene id: 1765967:BW247_RS02215
uniprot id: A0A1P8UDY4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1765967:BW247 RS05700
gene id: 1765967:BW247_RS05700
uniprot id: A0A1P8UFW5
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS13080
gene id: 1765967:BW247_RS13080
uniprot id: A0A1P8UJ91
names: Similarity
messages: Belongs to the PhoH family.

1765967:BW247 RS13255
gene id: 1765967:BW247_RS13255
uniprot id: A0A1P8UJB5
names: Similarity
messages: Belongs to the HPrK/P family.

1765967:BW247 RS01785
gene id: 1765967:BW247_RS01785
uniprot id: A0A1P8UDT6
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1765967:BW247 RS14060
gene id: 1765967:BW247_RS14060
uniprot id: A0A1P8UJS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1765967:BW247 RS00560
gene id: 1765967:BW247_RS00560
uniprot id: A0A1P8UD26
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1765967:BW247 RS05680
gene id: 1765967:BW247_RS05680
uniprot id: A0A1P8UFP7
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS03145
gene id: 1765967:BW247_RS03145
uniprot id: A0A1P8UEC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

1765967:BW247 RS07790
gene id: 1765967:BW247_RS07790
uniprot id: A0A1P8UGV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1765967:BW247 RS00285
gene id: 1765967:BW247_RS00285
uniprot id: A0A1P8UD04
names: Similarity
messages: Belongs to the LOG family.

1765967:BW247 RS07430
gene id: 1765967:BW247_RS07430
uniprot id: A0A1P8UGH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1765967:BW247 RS09620
gene id: 1765967:BW247_RS09620
uniprot id: A0A1P8UHQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

1765967:BW247 RS06340
gene id: 1765967:BW247_RS06340
uniprot id: A0A1P8UFX9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1765967:BW247 RS15720
gene id: 1765967:BW247_RS15720
uniprot id: A0A1P8UKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1765967:BW247 RS03640
gene id: 1765967:BW247_RS03640
uniprot id: A0A1P8UEL4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS11065
gene id: 1765967:BW247_RS11065
uniprot id: A0A1P8UIH1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1765967:BW247 RS14915
gene id: 1765967:BW247_RS14915
uniprot id: A0A1P8UK55
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1765967:BW247 RS11825
gene id: 1765967:BW247_RS11825
uniprot id: A0A1P8UIM5
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS14110
gene id: 1765967:BW247_RS14110
uniprot id: A0A1P8UJU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1765967:BW247 RS14045
gene id: 1765967:BW247_RS14045
uniprot id: A0A1P8UJQ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1765967:BW247 RS05065
gene id: 1765967:BW247_RS05065
uniprot id: A0A1P8UFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1765967:BW247 RS06995
gene id: 1765967:BW247_RS06995
uniprot id: A0A1P8UGG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1765967:BW247 RS07255
gene id: 1765967:BW247_RS07255
uniprot id: A0A1P8UGD8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1765967:BW247 RS04455
gene id: 1765967:BW247_RS04455
uniprot id: A0A1P8UF13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1765967:BW247 RS09830
gene id: 1765967:BW247_RS09830
uniprot id: A0A1P8UHN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1765967:BW247 RS09800
gene id: 1765967:BW247_RS09800
uniprot id: A0A1P8UHQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS00745
gene id: 1765967:BW247_RS00745
uniprot id: A0A1P8UD61
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1765967:BW247 RS08250
gene id: 1765967:BW247_RS08250
uniprot id: A0A1P8UH40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1765967:BW247 RS05710
gene id: 1765967:BW247_RS05710
uniprot id: A0A1P8UFP0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1765967:BW247 RS12905
gene id: 1765967:BW247_RS12905
uniprot id: A0A1P8UJ82
names: Similarity
messages: Belongs to the UPF0758 family.

1765967:BW247 RS02585
gene id: 1765967:BW247_RS02585
uniprot id: A0A1P8UE95
names: Similarity
messages: Belongs to the GSP E family.

1765967:BW247 RS05490
gene id: 1765967:BW247_RS05490
uniprot id: A0A1P8UFJ5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1765967:BW247 RS10895
gene id: 1765967:BW247_RS10895
uniprot id: A0A1P8UI63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1765967:BW247 RS04575
gene id: 1765967:BW247_RS04575
uniprot id: A0A1P8UL17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1765967:BW247 RS15430
gene id: 1765967:BW247_RS15430
uniprot id: A0A1P8UKL1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1765967:BW247 RS02705
gene id: 1765967:BW247_RS02705
uniprot id: A0A1P8UEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS16715
gene id: 1765967:BW247_RS16715
uniprot id: A0A1P8UKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1765967:BW247 RS01165
gene id: 1765967:BW247_RS01165
uniprot id: A0A1P8UDH5
names: Similarity
messages: Belongs to the UPF0162 family.

1765967:BW247 RS03385
gene id: 1765967:BW247_RS03385
uniprot id: A0A1P8UEJ2
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS04540
gene id: 1765967:BW247_RS04540
uniprot id: A0A1P8UF50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1765967:BW247 RS11925
gene id: 1765967:BW247_RS11925
uniprot id: A0A1P8UIQ8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1765967:BW247 RS08980
gene id: 1765967:BW247_RS08980
uniprot id: A0A1P8UHA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1765967:BW247 RS08940
gene id: 1765967:BW247_RS08940
uniprot id: A0A1P8UH74
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1765967:BW247 RS13260
gene id: 1765967:BW247_RS13260
uniprot id: A0A1P8UJB7
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1765967:BW247 RS13995
gene id: 1765967:BW247_RS13995
uniprot id: A0A1P8UJQ1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1765967:BW247 RS12985
gene id: 1765967:BW247_RS12985
uniprot id: A0A1P8UJ95
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1765967:BW247 RS05085
gene id: 1765967:BW247_RS05085
uniprot id: A0A1P8UFB7
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1765967:BW247 RS10265
gene id: 1765967:BW247_RS10265
uniprot id: A0A1P8UHW0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS04020
gene id: 1765967:BW247_RS04020
uniprot id: A0A1P8UEX7
names: Cofactor
names: Miscellaneous
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1765967:BW247 RS06465
gene id: 1765967:BW247_RS06465
uniprot id: A0A1P8UFZ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1765967:BW247 RS00930
gene id: 1765967:BW247_RS00930
uniprot id: A0A1P8UDH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1765967:BW247 RS15665
gene id: 1765967:BW247_RS15665
uniprot id: A0A1P8UKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS12925
gene id: 1765967:BW247_RS12925
uniprot id: A0A1P8UJC8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1765967:BW247 RS10815
gene id: 1765967:BW247_RS10815
uniprot id: A0A1P8UI56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1765967:BW247 RS01425
gene id: 1765967:BW247_RS01425
uniprot id: A0A1P8UDQ7
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS00655
gene id: 1765967:BW247_RS00655
uniprot id: A0A1P8UDB8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1765967:BW247 RS06655
gene id: 1765967:BW247_RS06655
uniprot id: A0A1P8UGB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1765967:BW247 RS08810
gene id: 1765967:BW247_RS08810
uniprot id: A0A1P8UH78
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS04050
gene id: 1765967:BW247_RS04050
uniprot id: A0A1P8UF17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1765967:BW247 RS00660
gene id: 1765967:BW247_RS00660
uniprot id: A0A1P8UD46
names: Similarity
messages: Belongs to the glutamine synthetase family.

1765967:BW247 RS02115
gene id: 1765967:BW247_RS02115
uniprot id: A0A1P8UE23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1765967:BW247 RS02405
gene id: 1765967:BW247_RS02405
uniprot id: A0A1P8UDZ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1765967:BW247 RS01990
gene id: 1765967:BW247_RS01990
uniprot id: A0A1P8UE03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1765967:BW247 RS15390
gene id: 1765967:BW247_RS15390
uniprot id: A0A1P8UKG7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1765967:BW247 RS03820
gene id: 1765967:BW247_RS03820
uniprot id: A0A1P8UEN8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1765967:BW247 RS07205
gene id: 1765967:BW247_RS07205
uniprot id: A0A1P8UGC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1765967:BW247 RS15280
gene id: 1765967:BW247_RS15280
uniprot id: A0A1P8UKG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS13420
gene id: 1765967:BW247_RS13420
uniprot id: A0A1P8UJF2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1765967:BW247 RS03960
gene id: 1765967:BW247_RS03960
uniprot id: A0A1P8UEY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1765967:BW247 RS05870
gene id: 1765967:BW247_RS05870
uniprot id: A0A1P8UFR0
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1765967:BW247 RS04615
gene id: 1765967:BW247_RS04615
uniprot id: A0A1P8UF93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS02630
gene id: 1765967:BW247_RS02630
uniprot id: A0A1P8UEA0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1765967:BW247 RS06675
gene id: 1765967:BW247_RS06675
uniprot id: A0A1P8UG74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1765967:BW247 RS03875
gene id: 1765967:BW247_RS03875
uniprot id: A0A1P8UEZ3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1765967:BW247 RS02195
gene id: 1765967:BW247_RS02195
uniprot id: A0A1P8UDW5
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS15620
gene id: 1765967:BW247_RS15620
uniprot id: A0A1P8UKJ5
names: Similarity
messages: Belongs to the CTP synthase family.

1765967:BW247 RS02505
gene id: 1765967:BW247_RS02505
uniprot id: A0A1P8UEB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1765967:BW247 RS00605
gene id: 1765967:BW247_RS00605
uniprot id: A0A1P8UD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1765967:BW247 RS00640
gene id: 1765967:BW247_RS00640
uniprot id: A0A1P8UDC2
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS01460
gene id: 1765967:BW247_RS01460
uniprot id: A0A1P8UDK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1765967:BW247 RS11690
gene id: 1765967:BW247_RS11690
uniprot id: A0A1P8UIK2
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1765967:BW247 RS07160
gene id: 1765967:BW247_RS07160
uniprot id: A0A1P8UL81
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1765967:BW247 RS14330
gene id: 1765967:BW247_RS14330
uniprot id: A0A1P8UK24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1765967:BW247 RS16120
gene id: 1765967:BW247_RS16120
uniprot id: A0A1P8UKU0
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1765967:BW247 RS14695
gene id: 1765967:BW247_RS14695
uniprot id: A0A1P8UK22
names: Subcellular Location Annotation
messages: Cytoplasm

1765967:BW247 RS02700
gene id: 1765967:BW247_RS02700
uniprot id: A0A1P8UEA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1765967:BW247 RS07510
gene id: 1765967:BW247_RS07510
uniprot id: A0A1P8UGJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS14950
gene id: 1765967:BW247_RS14950
uniprot id: A0A1P8UK75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1765967:BW247 RS10975
gene id: 1765967:BW247_RS10975
uniprot id: A0A1P8UI90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1765967:BW247 RS06395
gene id: 1765967:BW247_RS06395
uniprot id: A0A1P8UG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1765967:BW247 RS11365
gene id: 1765967:BW247_RS11365
uniprot id: A0A1P8UIE5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1765967:BW247 RS15725
gene id: 1765967:BW247_RS15725
uniprot id: A0A1P8UKI4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1765967:BW247 RS05845
gene id: 1765967:BW247_RS05845
uniprot id: A0A1P8UFU5
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1765967:BW247 RS05310
gene id: 1765967:BW247_RS05310
uniprot id: A0A1P8UFG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1765967:BW247 RS02300
gene id: 1765967:BW247_RS02300
uniprot id: A0A1P8UL64
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1765967:BW247 RS11845
gene id: 1765967:BW247_RS11845
uniprot id: A0A1P8UIQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1765967:BW247 RS01270
gene id: 1765967:BW247_RS01270
uniprot id: A0A1P8UDH6
names: Similarity
messages: Belongs to the peptidase S41A family.

1765967:BW247 RS11565
gene id: 1765967:BW247_RS11565
uniprot id: A0A1P8UII5
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1765967:BW247 RS14770
gene id: 1765967:BW247_RS14770
uniprot id: A0A1P8UK31
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1765967:BW247 RS11230
gene id: 1765967:BW247_RS11230
uniprot id: A0A1P8UIC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1765967:BW247 RS12840
gene id: 1765967:BW247_RS12840
uniprot id: A0A1P8UJ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS15805
gene id: 1765967:BW247_RS15805
uniprot id: A0A1P8UKL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1765967:BW247 RS00470
gene id: 1765967:BW247_RS00470
uniprot id: A0A1P8UD23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS01730
gene id: 1765967:BW247_RS01730
uniprot id: A0A1P8UDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1765967:BW247 RS11185
gene id: 1765967:BW247_RS11185
uniprot id: A0A1P8UIB9
names: Similarity
messages: Belongs to the group II decarboxylase family.

1765967:BW247 RS03105
gene id: 1765967:BW247_RS03105
uniprot id: A0A1P8UEC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1765967:BW247 RS11520
gene id: 1765967:BW247_RS11520
uniprot id: A0A1P8UIJ6
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1765967:BW247 RS08110
gene id: 1765967:BW247_RS08110
uniprot id: A0A1P8UGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1765967:BW247 RS10900
gene id: 1765967:BW247_RS10900
uniprot id: A0A1P8UIE6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1765967:BW247 RS03945
gene id: 1765967:BW247_RS03945
uniprot id: A0A1P8UET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1765967:BW247 RS11835
gene id: 1765967:BW247_RS11835
uniprot id: A0A1P8UIM7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1765967:BW247 RS03715
gene id: 1765967:BW247_RS03715
uniprot id: A0A1P8UEM3
names: Similarity
messages: Belongs to the PhoH family.

1765967:BW247 RS14585
gene id: 1765967:BW247_RS14585
uniprot id: A0A1P8UK02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1765967:BW247 RS04625
gene id: 1765967:BW247_RS04625
uniprot id: A0A1P8UL20
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1765967:BW247 RS14005
gene id: 1765967:BW247_RS14005
uniprot id: A0A1P8UJR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1765967:BW247 RS07710
gene id: 1765967:BW247_RS07710
uniprot id: A0A1P8UGU3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1765967:BW247 RS13065
gene id: 1765967:BW247_RS13065
uniprot id: A0A1P8UJA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1765967:BW247 RS05665
gene id: 1765967:BW247_RS05665
uniprot id: A0A1P8UFP3
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1765967:BW247 RS05965
gene id: 1765967:BW247_RS05965
uniprot id: A0A1P8UL80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS15065
gene id: 1765967:BW247_RS15065
uniprot id: A0A1P8UK93
names: Similarity
messages: Belongs to the thioredoxin family.

1765967:BW247 RS13005
gene id: 1765967:BW247_RS13005
uniprot id: A0A1P8UJ94
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1765967:BW247 RS02285
gene id: 1765967:BW247_RS02285
uniprot id: A0A1P8UE50
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS05715
gene id: 1765967:BW247_RS05715
uniprot id: A0A1P8UFP1
names: Similarity
messages: Belongs to the UPF0434 family.

1765967:BW247 RS11525
gene id: 1765967:BW247_RS11525
uniprot id: A0A1P8UIH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1765967:BW247 RS14050
gene id: 1765967:BW247_RS14050
uniprot id: A0A1P8UJQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1765967:BW247 RS03870
gene id: 1765967:BW247_RS03870
uniprot id: A0A1P8UEP7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1765967:BW247 RS15365
gene id: 1765967:BW247_RS15365
uniprot id: A0A1P8UKE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1765967:BW247 RS14400
gene id: 1765967:BW247_RS14400
uniprot id: A0A1P8UJX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1765967:BW247 RS14015
gene id: 1765967:BW247_RS14015
uniprot id: A0A1P8UJZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1765967:BW247 RS01780
gene id: 1765967:BW247_RS01780
uniprot id: A0A1P8UDP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1765967:BW247 RS03810
gene id: 1765967:BW247_RS03810
uniprot id: A0A1P8UER9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1765967:BW247 RS08085
gene id: 1765967:BW247_RS08085
uniprot id: A0A1P8UH11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1765967:BW247 RS14115
gene id: 1765967:BW247_RS14115
uniprot id: A0A1P8UJV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1765967:BW247 RS14515
gene id: 1765967:BW247_RS14515
uniprot id: A0A1P8UJZ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1765967:BW247 RS02500
gene id: 1765967:BW247_RS02500
uniprot id: A0A1P8UE48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1765967:BW247 RS00840
gene id: 1765967:BW247_RS00840
uniprot id: A0A1P8UDH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS01060
gene id: 1765967:BW247_RS01060
uniprot id: A0A1P8UKY1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1765967:BW247 RS12875
gene id: 1765967:BW247_RS12875
uniprot id: A0A1P8UJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1765967:BW247 RS02620
gene id: 1765967:BW247_RS02620
uniprot id: A0A1P8UE88
names: Similarity
messages: Belongs to the CutA family.

1765967:BW247 RS12965
gene id: 1765967:BW247_RS12965
uniprot id: A0A1P8UJ72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1765967:BW247 RS11705
gene id: 1765967:BW247_RS11705
uniprot id: A0A1P8UIT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1765967:BW247 RS15215
gene id: 1765967:BW247_RS15215
uniprot id: A0A1P8UKF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS03525
gene id: 1765967:BW247_RS03525
uniprot id: A0A1P8UER5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1765967:BW247 RS14310
gene id: 1765967:BW247_RS14310
uniprot id: A0A1P8UJV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1765967:BW247 RS08270
gene id: 1765967:BW247_RS08270
uniprot id: A0A1P8UGX4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS01310
gene id: 1765967:BW247_RS01310
uniprot id: A0A1P8UDL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS03910
gene id: 1765967:BW247_RS03910
uniprot id: A0A1P8UEU1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1765967:BW247 RS11920
gene id: 1765967:BW247_RS11920
uniprot id: A0A1P8UIW4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1765967:BW247 RS00065
gene id: 1765967:BW247_RS00065
uniprot id: A0A1P8UD27
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1765967:BW247 RS02295
gene id: 1765967:BW247_RS02295
uniprot id: A0A1P8UDX9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1765967:BW247 RS00770
gene id: 1765967:BW247_RS00770
uniprot id: A0A1P8UDE4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1765967:BW247 RS03235
gene id: 1765967:BW247_RS03235
uniprot id: A0A1P8UEF1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1765967:BW247 RS15245
gene id: 1765967:BW247_RS15245
uniprot id: A0A1P8UKB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1765967:BW247 RS13035
gene id: 1765967:BW247_RS13035
uniprot id: A0A1P8UJ89
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1765967:BW247 RS11175
gene id: 1765967:BW247_RS11175
uniprot id: A0A1P8UII9
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS14040
gene id: 1765967:BW247_RS14040
uniprot id: A0A1P8UJS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1765967:BW247 RS14160
gene id: 1765967:BW247_RS14160
uniprot id: A0A1P8UJT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1765967:BW247 RS03010
gene id: 1765967:BW247_RS03010
uniprot id: A0A1P8UL96
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1765967:BW247 RS05690
gene id: 1765967:BW247_RS05690
uniprot id: A0A1P8UFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1765967:BW247 RS14185
gene id: 1765967:BW247_RS14185
uniprot id: A0A1P8UJU5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1765967:BW247 RS11415
gene id: 1765967:BW247_RS11415
uniprot id: A0A1P8UIG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1765967:BW247 RS00950
gene id: 1765967:BW247_RS00950
uniprot id: A0A1P8UDD5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS12460
gene id: 1765967:BW247_RS12460
uniprot id: A0A1P8UIZ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1765967:BW247 RS01390
gene id: 1765967:BW247_RS01390
uniprot id: A0A1P8UDM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1765967:BW247 RS09390
gene id: 1765967:BW247_RS09390
uniprot id: A0A1P8UHH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1765967:BW247 RS07145
gene id: 1765967:BW247_RS07145
uniprot id: A0A1P8UGC3
names: Cofactor
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1765967:BW247 RS05540
gene id: 1765967:BW247_RS05540
uniprot id: A0A1P8UFJ5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1765967:BW247 RS07045
gene id: 1765967:BW247_RS07045
uniprot id: A0A1P8UG99
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1765967:BW247 RS10025
gene id: 1765967:BW247_RS10025
uniprot id: A0A1P8UHV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1765967:BW247 RS07095
gene id: 1765967:BW247_RS07095
uniprot id: A0A1P8UGC7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1765967:BW247 RS07275
gene id: 1765967:BW247_RS07275
uniprot id: A0A1P8UGE1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1765967:BW247 RS00760
gene id: 1765967:BW247_RS00760
uniprot id: A0A1P8UD74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1765967:BW247 RS00280
gene id: 1765967:BW247_RS00280
uniprot id: A0A1P8UCZ6
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1765967:BW247 RS07775
gene id: 1765967:BW247_RS07775
uniprot id: A0A1P8ULA3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1765967:BW247 RS02360
gene id: 1765967:BW247_RS02360
uniprot id: A0A1P8UDZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS08300
gene id: 1765967:BW247_RS08300
uniprot id: A0A1P8UH03
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1765967:BW247 RS14205
gene id: 1765967:BW247_RS14205
uniprot id: A0A1P8UJY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

1765967:BW247 RS13465
gene id: 1765967:BW247_RS13465
uniprot id: A0A1P8UJG4
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1765967:BW247 RS00835
gene id: 1765967:BW247_RS00835
uniprot id: A0A1P8UDB7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS07270
gene id: 1765967:BW247_RS07270
uniprot id: A0A1P8UGF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1765967:BW247 RS00535
gene id: 1765967:BW247_RS00535
uniprot id: A0A1P8UDA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1765967:BW247 RS15595
gene id: 1765967:BW247_RS15595
uniprot id: A0A1P8UKJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1765967:BW247 RS02675
gene id: 1765967:BW247_RS02675
uniprot id: A0A1P8UE63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1765967:BW247 RS09550
gene id: 1765967:BW247_RS09550
uniprot id: A0A1P8UHK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1765967:BW247 RS09230
gene id: 1765967:BW247_RS09230
uniprot id: A0A1P8UHC8
names: Similarity
messages: Belongs to the phosphorylase b kinase regulatory chain family.

1765967:BW247 RS16080
gene id: 1765967:BW247_RS16080
uniprot id: A0A1P8UKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1765967:BW247 RS01625
gene id: 1765967:BW247_RS01625
uniprot id: A0A1P8UDL5
names: Similarity
messages: Belongs to the P(II) protein family.

1765967:BW247 RS15935
gene id: 1765967:BW247_RS15935
uniprot id: A0A1P8UKM7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1765967:BW247 RS14760
gene id: 1765967:BW247_RS14760
uniprot id: A0A1P8UKB1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1765967:BW247 RS15285
gene id: 1765967:BW247_RS15285
uniprot id: A0A1P8UKE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1765967:BW247 RS07020
gene id: 1765967:BW247_RS07020
uniprot id: A0A1P8UGC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS13480
gene id: 1765967:BW247_RS13480
uniprot id: A0A1P8UJG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1765967:BW247 RS10720
gene id: 1765967:BW247_RS10720
uniprot id: A0A1P8UI38
names: Similarity
messages: Belongs to the bacterioferritin family.

1765967:BW247 RS09160
gene id: 1765967:BW247_RS09160
uniprot id: A0A1P8UHD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1765967:BW247 RS08485
gene id: 1765967:BW247_RS08485
uniprot id: A0A1P8UH15
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1765967:BW247 RS08180
gene id: 1765967:BW247_RS08180
uniprot id: A0A1P8UL99
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1765967:BW247 RS13915
gene id: 1765967:BW247_RS13915
uniprot id: A0A1P8UJM7
names: Similarity
messages: Belongs to the BolA/IbaG family.

1765967:BW247 RS07650
gene id: 1765967:BW247_RS07650
uniprot id: A0A1P8UGM0
names: Similarity
messages: Belongs to the MotB family.

1765967:BW247 RS00415
gene id: 1765967:BW247_RS00415
uniprot id: A0A1P8UKS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1765967:BW247 RS13135
gene id: 1765967:BW247_RS13135
uniprot id: A0A1P8UJB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS00590
gene id: 1765967:BW247_RS00590
uniprot id: A0A1P8UD48
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1765967:BW247 RS12885
gene id: 1765967:BW247_RS12885
uniprot id: A0A1P8UJ75
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1765967:BW247 RS04895
gene id: 1765967:BW247_RS04895
uniprot id: A0A1P8UFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1765967:BW247 RS01275
gene id: 1765967:BW247_RS01275
uniprot id: A0A1P8UDM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1765967:BW247 RS09485
gene id: 1765967:BW247_RS09485
uniprot id: A0A1P8UHJ8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1765967:BW247 RS12645
gene id: 1765967:BW247_RS12645
uniprot id: A0A1P8UJ38
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS09385
gene id: 1765967:BW247_RS09385
uniprot id: A0A1P8UHM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1765967:BW247 RS06065
gene id: 1765967:BW247_RS06065
uniprot id: A0A1P8UG26
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS05605
gene id: 1765967:BW247_RS05605
uniprot id: A0A1P8UFN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1765967:BW247 RS00260
gene id: 1765967:BW247_RS00260
uniprot id: A0A1P8UD37
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1765967:BW247 RS11360
gene id: 1765967:BW247_RS11360
uniprot id: A0A1P8UIF3
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1765967:BW247 RS14120
gene id: 1765967:BW247_RS14120
uniprot id: A0A1P8UK06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1765967:BW247 RS09870
gene id: 1765967:BW247_RS09870
uniprot id: A0A1P8UHR1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1765967:BW247 RS01710
gene id: 1765967:BW247_RS01710
uniprot id: A0A1P8UDV1
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1765967:BW247 RS05755
gene id: 1765967:BW247_RS05755
uniprot id: A0A1P8UFP2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1765967:BW247 RS03020
gene id: 1765967:BW247_RS03020
uniprot id: A0A1P8UEE1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1765967:BW247 RS02845
gene id: 1765967:BW247_RS02845
uniprot id: A0A1P8UL01
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1765967:BW247 RS11125
gene id: 1765967:BW247_RS11125
uniprot id: A0A1P8UIB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1765967:BW247 RS12760
gene id: 1765967:BW247_RS12760
uniprot id: A0A1P8UJ96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1765967:BW247 RS00580
gene id: 1765967:BW247_RS00580
uniprot id: A0A1P8UDB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1765967:BW247 RS15090
gene id: 1765967:BW247_RS15090
uniprot id: A0A1P8UK91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1765967:BW247 RS11265
gene id: 1765967:BW247_RS11265
uniprot id: A0A1P8ULK0
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS10445
gene id: 1765967:BW247_RS10445
uniprot id: A0A1P8UI33
names: Similarity
messages: Belongs to the RelE toxin family.

1765967:BW247 RS15500
gene id: 1765967:BW247_RS15500
uniprot id: A0A1P8UKM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1765967:BW247 RS06910
gene id: 1765967:BW247_RS06910
uniprot id: A0A1P8UG76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1765967:BW247 RS08815
gene id: 1765967:BW247_RS08815
uniprot id: A0A1P8UH89
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1765967:BW247 RS09125
gene id: 1765967:BW247_RS09125
uniprot id: A0A1P8UHB1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS00785
gene id: 1765967:BW247_RS00785
uniprot id: A0A1P8UDA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1765967:BW247 RS15640
gene id: 1765967:BW247_RS15640
uniprot id: A0A1P8UKN9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1765967:BW247 RS09200
gene id: 1765967:BW247_RS09200
uniprot id: A0A1P8UHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1765967:BW247 RS00465
gene id: 1765967:BW247_RS00465
uniprot id: A0A1P8UKU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1765967:BW247 RS04330
gene id: 1765967:BW247_RS04330
uniprot id: A0A1P8UEZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1765967:BW247 RS11545
gene id: 1765967:BW247_RS11545
uniprot id: A0A1P8UII2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1765967:BW247 RS04880
gene id: 1765967:BW247_RS04880
uniprot id: A0A1P8UF91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1765967:BW247 RS14675
gene id: 1765967:BW247_RS14675
uniprot id: A0A1P8UK15
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1765967:BW247 RS04215
gene id: 1765967:BW247_RS04215
uniprot id: A0A1P8UF51
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1765967:BW247 RS13730
gene id: 1765967:BW247_RS13730
uniprot id: A0A1P8UJP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS15605
gene id: 1765967:BW247_RS15605
uniprot id: A0A1P8UKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS07945
gene id: 1765967:BW247_RS07945
uniprot id: A0A1P8UGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1765967:BW247 RS00290
gene id: 1765967:BW247_RS00290
uniprot id: A0A1P8UD63
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1765967:BW247 RS00790
gene id: 1765967:BW247_RS00790
uniprot id: A0A1P8UDG7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1765967:BW247 RS00005
gene id: 1765967:BW247_RS00005
uniprot id: A0A1P8UCT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1765967:BW247 RS03585
gene id: 1765967:BW247_RS03585
uniprot id: A0A1P8UEK5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1765967:BW247 RS06620
gene id: 1765967:BW247_RS06620
uniprot id: A0A1P8UG66
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1765967:BW247 RS12485
gene id: 1765967:BW247_RS12485
uniprot id: A0A1P8UJ03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1765967:BW247 RS07665
gene id: 1765967:BW247_RS07665
uniprot id: A0A1P8UGN0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1765967:BW247 RS07230
gene id: 1765967:BW247_RS07230
uniprot id: A0A1P8UGC4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1765967:BW247 RS01615
gene id: 1765967:BW247_RS01615
uniprot id: A0A1P8UDN5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1765967:BW247 RS10005
gene id: 1765967:BW247_RS10005
uniprot id: A0A1P8UHS5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1765967:BW247 RS10315
gene id: 1765967:BW247_RS10315
uniprot id: A0A1P8UHX9
names: Similarity
messages: Belongs to the HsdR family.

1765967:BW247 RS00830
gene id: 1765967:BW247_RS00830
uniprot id: A0A1P8UD78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1765967:BW247 RS17090
gene id: 1765967:BW247_RS17090
uniprot id: A0A1P8UJE3
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1765967:BW247 RS02065
gene id: 1765967:BW247_RS02065
uniprot id: A0A1P8UDU4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1765967:BW247 RS03775
gene id: 1765967:BW247_RS03775
uniprot id: A0A1P8UEP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1765967:BW247 RS07240
gene id: 1765967:BW247_RS07240
uniprot id: A0A1P8UGI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1765967:BW247 RS02605
gene id: 1765967:BW247_RS02605
uniprot id: A0A1P8UE66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1765967:BW247 RS11275
gene id: 1765967:BW247_RS11275
uniprot id: A0A1P8UIE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1765967:BW247 RS03905
gene id: 1765967:BW247_RS03905
uniprot id: A0A1P8UET9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1765967:BW247 RS12745
gene id: 1765967:BW247_RS12745
uniprot id: A0A1P8UJ31
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1765967:BW247 RS06515
gene id: 1765967:BW247_RS06515
uniprot id: A0A1P8UG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS02785
gene id: 1765967:BW247_RS02785
uniprot id: A0A1P8UE60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1765967:BW247 RS01255
gene id: 1765967:BW247_RS01255
uniprot id: A0A1P8UDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1765967:BW247 RS12935
gene id: 1765967:BW247_RS12935
uniprot id: A0A1P8UJ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1765967:BW247 RS01945
gene id: 1765967:BW247_RS01945
uniprot id: A0A1P8UDW4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1765967:BW247 RS10800
gene id: 1765967:BW247_RS10800
uniprot id: A0A1P8UI41
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1765967:BW247 RS06990
gene id: 1765967:BW247_RS06990
uniprot id: A0A1P8UGE6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1765967:BW247 RS12830
gene id: 1765967:BW247_RS12830
uniprot id: A0A1P8UJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS03270
gene id: 1765967:BW247_RS03270
uniprot id: A0A1P8UEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1765967:BW247 RS13235
gene id: 1765967:BW247_RS13235
uniprot id: A0A1P8UJC1
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1765967:BW247 RS13540
gene id: 1765967:BW247_RS13540
uniprot id: A0A1P8UJH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS07495
gene id: 1765967:BW247_RS07495
uniprot id: A0A1P8UGK3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS02800
gene id: 1765967:BW247_RS02800
uniprot id: A0A1P8UEG6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1765967:BW247 RS04815
gene id: 1765967:BW247_RS04815
uniprot id: A0A1P8UF66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS10160
gene id: 1765967:BW247_RS10160
uniprot id: A0A1P8UHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS09250
gene id: 1765967:BW247_RS09250
uniprot id: A0A1P8UHG2
names: Similarity
messages: Belongs to the PspA/IM30 family.

1765967:BW247 RS07185
gene id: 1765967:BW247_RS07185
uniprot id: A0A1P8UGF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1765967:BW247 RS05110
gene id: 1765967:BW247_RS05110
uniprot id: A0A1P8UFF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1765967:BW247 RS12600
gene id: 1765967:BW247_RS12600
uniprot id: A0A1P8UJ40
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1765967:BW247 RS15435
gene id: 1765967:BW247_RS15435
uniprot id: A0A1P8UKF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1765967:BW247 RS05250
gene id: 1765967:BW247_RS05250
uniprot id: A0A1P8UFF3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1765967:BW247 RS09410
gene id: 1765967:BW247_RS09410
uniprot id: A0A1P8UHG5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1765967:BW247 RS06470
gene id: 1765967:BW247_RS06470
uniprot id: A0A1P8UG22
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1765967:BW247 RS02435
gene id: 1765967:BW247_RS02435
uniprot id: A0A1P8UE41
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS15005
gene id: 1765967:BW247_RS15005
uniprot id: A0A1P8UK70
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS12870
gene id: 1765967:BW247_RS12870
uniprot id: A0A1P8UJ81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1765967:BW247 RS12790
gene id: 1765967:BW247_RS12790
uniprot id: A0A1P8UJ39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS15830
gene id: 1765967:BW247_RS15830
uniprot id: A0A1P8UKQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1765967:BW247 RS13100
gene id: 1765967:BW247_RS13100
uniprot id: A0A1P8UJD3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS03950
gene id: 1765967:BW247_RS03950
uniprot id: A0A1P8UEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS08175
gene id: 1765967:BW247_RS08175
uniprot id: A0A1P8UGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1765967:BW247 RS02850
gene id: 1765967:BW247_RS02850
uniprot id: A0A1P8UE77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1765967:BW247 RS15205
gene id: 1765967:BW247_RS15205
uniprot id: A0A1P8UKI2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1765967:BW247 RS12585
gene id: 1765967:BW247_RS12585
uniprot id: A0A1P8UJ24
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1765967:BW247 RS05760
gene id: 1765967:BW247_RS05760
uniprot id: A0A1P8UFP6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1765967:BW247 RS06090
gene id: 1765967:BW247_RS06090
uniprot id: A0A1P8UFU6
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1765967:BW247 RS03135
gene id: 1765967:BW247_RS03135
uniprot id: A0A1P8UEG0
names: Similarity
messages: Belongs to the peptidase M1 family.

1765967:BW247 RS12750
gene id: 1765967:BW247_RS12750
uniprot id: A0A1P8UJ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1765967:BW247 RS14340
gene id: 1765967:BW247_RS14340
uniprot id: A0A1P8UJZ6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1765967:BW247 RS07370
gene id: 1765967:BW247_RS07370
uniprot id: A0A1P8ULC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS11580
gene id: 1765967:BW247_RS11580
uniprot id: A0A1P8UII6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1765967:BW247 RS15225
gene id: 1765967:BW247_RS15225
uniprot id: A0A1P8UKA5
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS09040
gene id: 1765967:BW247_RS09040
uniprot id: A0A1P8UHC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1765967:BW247 RS09095
gene id: 1765967:BW247_RS09095
uniprot id: A0A1P8UHC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1765967:BW247 RS14655
gene id: 1765967:BW247_RS14655
uniprot id: A0A1P8UK87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1765967:BW247 RS14440
gene id: 1765967:BW247_RS14440
uniprot id: A0A1P8UJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS08340
gene id: 1765967:BW247_RS08340
uniprot id: A0A1P8UGX5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1765967:BW247 RS14150
gene id: 1765967:BW247_RS14150
uniprot id: A0A1P8UJS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS03310
gene id: 1765967:BW247_RS03310
uniprot id: A0A1P8UEI5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1765967:BW247 RS10115
gene id: 1765967:BW247_RS10115
uniprot id: A0A1P8UHV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1765967:BW247 RS14765
gene id: 1765967:BW247_RS14765
uniprot id: A0A1P8ULN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1765967:BW247 RS01965
gene id: 1765967:BW247_RS01965
uniprot id: A0A1P8UE25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1765967:BW247 RS04525
gene id: 1765967:BW247_RS04525
uniprot id: A0A1P8UF14
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1765967:BW247 RS03745
gene id: 1765967:BW247_RS03745
uniprot id: A0A1P8UL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1765967:BW247 RS07880
gene id: 1765967:BW247_RS07880
uniprot id: A0A1P8UGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1765967:BW247 RS11440
gene id: 1765967:BW247_RS11440
uniprot id: A0A1P8UIF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS04635
gene id: 1765967:BW247_RS04635
uniprot id: A0A1P8UF41
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1765967:BW247 RS06825
gene id: 1765967:BW247_RS06825
uniprot id: A0A1P8UGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1765967:BW247 RS06730
gene id: 1765967:BW247_RS06730
uniprot id: A0A1P8UGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS02635
gene id: 1765967:BW247_RS02635
uniprot id: A0A1P8UEA8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1765967:BW247 RS07680
gene id: 1765967:BW247_RS07680
uniprot id: A0A1P8UGJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1765967:BW247 RS06960
gene id: 1765967:BW247_RS06960
uniprot id: A0A1P8UGH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1765967:BW247 RS16160
gene id: 1765967:BW247_RS16160
uniprot id: A0A1P8UKV2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1765967:BW247 RS09175
gene id: 1765967:BW247_RS09175
uniprot id: A0A1P8UHC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1765967:BW247 RS16115
gene id: 1765967:BW247_RS16115
uniprot id: A0A1P8UKR0
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS05985
gene id: 1765967:BW247_RS05985
uniprot id: A0A1P8UFS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1765967:BW247 RS03220
gene id: 1765967:BW247_RS03220
uniprot id: A0A1P8UEE5
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1765967:BW247 RS13510
gene id: 1765967:BW247_RS13510
uniprot id: A0A1P8UJJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1765967:BW247 RS01750
gene id: 1765967:BW247_RS01750
uniprot id: A0A1P8UDU5
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1765967:BW247 RS06815
gene id: 1765967:BW247_RS06815
uniprot id: A0A1P8UG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS05135
gene id: 1765967:BW247_RS05135
uniprot id: A0A1P8UFD7
names: Similarity
messages: Belongs to the GSP E family.

1765967:BW247 RS08985
gene id: 1765967:BW247_RS08985
uniprot id: A0A1P8ULJ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS12270
gene id: 1765967:BW247_RS12270
uniprot id: A0A1P8ULI4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1765967:BW247 RS10735
gene id: 1765967:BW247_RS10735
uniprot id: A0A1P8UI34
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1765967:BW247 RS03575
gene id: 1765967:BW247_RS03575
uniprot id: A0A1P8UEL7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1765967:BW247 RS07460
gene id: 1765967:BW247_RS07460
uniprot id: A0A1P8UGF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1765967:BW247 RS11595
gene id: 1765967:BW247_RS11595
uniprot id: A0A1P8UIQ9
names: Similarity
messages: Belongs to the fabD family.

1765967:BW247 RS09980
gene id: 1765967:BW247_RS09980
uniprot id: A0A1P8UHQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1765967:BW247 RS11055
gene id: 1765967:BW247_RS11055
uniprot id: A0A1P8UIA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1765967:BW247 RS13435
gene id: 1765967:BW247_RS13435
uniprot id: A0A1P8UJI4
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS11435
gene id: 1765967:BW247_RS11435
uniprot id: A0A1P8UIG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1765967:BW247 RS09185
gene id: 1765967:BW247_RS09185
uniprot id: A0A1P8UHJ4
names: Similarity
messages: Belongs to the ArsC family.

1765967:BW247 RS02345
gene id: 1765967:BW247_RS02345
uniprot id: A0A1P8UE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1765967:BW247 RS11585
gene id: 1765967:BW247_RS11585
uniprot id: A0A1P8UII3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1765967:BW247 RS03940
gene id: 1765967:BW247_RS03940
uniprot id: A0A1P8UF03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS14830
gene id: 1765967:BW247_RS14830
uniprot id: A0A1P8UK78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1765967:BW247 RS02335
gene id: 1765967:BW247_RS02335
uniprot id: A0A1P8UDY7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS08635
gene id: 1765967:BW247_RS08635
uniprot id: A0A1P8UH36
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1765967:BW247 RS09150
gene id: 1765967:BW247_RS09150
uniprot id: A0A1P8UHD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1765967:BW247 RS10250
gene id: 1765967:BW247_RS10250
uniprot id: A0A1P8UHZ9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS02100
gene id: 1765967:BW247_RS02100
uniprot id: A0A1P8UDU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS13215
gene id: 1765967:BW247_RS13215
uniprot id: A0A1P8UJG8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1765967:BW247 RS02440
gene id: 1765967:BW247_RS02440
uniprot id: A0A1P8UE99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1765967:BW247 RS14460
gene id: 1765967:BW247_RS14460
uniprot id: A0A1P8UJY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1765967:BW247 RS11745
gene id: 1765967:BW247_RS11745
uniprot id: A0A1P8UIK8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1765967:BW247 RS00175
gene id: 1765967:BW247_RS00175
uniprot id: A0A1P8UD41
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1765967:BW247 RS03480
gene id: 1765967:BW247_RS03480
uniprot id: A0A1P8UEM8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1765967:BW247 RS13700
gene id: 1765967:BW247_RS13700
uniprot id: A0A1P8UJK0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1765967:BW247 RS00020
gene id: 1765967:BW247_RS00020
uniprot id: A0A1P8UCV4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1765967:BW247 RS03595
gene id: 1765967:BW247_RS03595
uniprot id: A0A1P8UEK8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS09555
gene id: 1765967:BW247_RS09555
uniprot id: A0A1P8UHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1765967:BW247 RS16145
gene id: 1765967:BW247_RS16145
uniprot id: A0A1P8UKS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1765967:BW247 RS09660
gene id: 1765967:BW247_RS09660
uniprot id: A0A1P8ULE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

1765967:BW247 RS09635
gene id: 1765967:BW247_RS09635
uniprot id: A0A1P8UHL2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS06200
gene id: 1765967:BW247_RS06200
uniprot id: A0A1P8UFX7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1765967:BW247 RS01510
gene id: 1765967:BW247_RS01510
uniprot id: A0A1P8UDU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS15970
gene id: 1765967:BW247_RS15970
uniprot id: A0A1P8UKT8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1765967:BW247 RS15585
gene id: 1765967:BW247_RS15585
uniprot id: A0A1P8UKM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS02805
gene id: 1765967:BW247_RS02805
uniprot id: A0A1P8UE87
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS16110
gene id: 1765967:BW247_RS16110
uniprot id: A0A1P8UKQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1765967:BW247 RS01930
gene id: 1765967:BW247_RS01930
uniprot id: A0A1P8UKV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1765967:BW247 RS10725
gene id: 1765967:BW247_RS10725
uniprot id: A0A1P8UIB8
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1765967:BW247 RS15195
gene id: 1765967:BW247_RS15195
uniprot id: A0A1P8UKB2
names: Similarity
messages: Belongs to the pyruvate kinase family.

1765967:BW247 RS01480
gene id: 1765967:BW247_RS01480
uniprot id: A0A1P8UDR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1765967:BW247 RS12635
gene id: 1765967:BW247_RS12635
uniprot id: A0A1P8UJ77
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

1765967:BW247 RS13935
gene id: 1765967:BW247_RS13935
uniprot id: A0A1P8UJP1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS00080
gene id: 1765967:BW247_RS00080
uniprot id: A0A1P8UD36
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1765967:BW247 RS00855
gene id: 1765967:BW247_RS00855
uniprot id: A0A1P8UD83
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS10285
gene id: 1765967:BW247_RS10285
uniprot id: A0A1P8UHW5
names: Similarity
messages: Belongs to the UPF0145 family.

1765967:BW247 RS15745
gene id: 1765967:BW247_RS15745
uniprot id: A0A1P8UKI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1765967:BW247 RS01235
gene id: 1765967:BW247_RS01235
uniprot id: A0A1P8UDH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1765967:BW247 RS09495
gene id: 1765967:BW247_RS09495
uniprot id: A0A1P8UHI9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1765967:BW247 RS13695
gene id: 1765967:BW247_RS13695
uniprot id: A0A1P8UJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS02580
gene id: 1765967:BW247_RS02580
uniprot id: A0A1P8UE90
names: Similarity
messages: Belongs to the GSP E family.

1765967:BW247 RS07260
gene id: 1765967:BW247_RS07260
uniprot id: A0A1P8UGM4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1765967:BW247 RS01530
gene id: 1765967:BW247_RS01530
uniprot id: A0A1P8UDS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1765967:BW247 RS15305
gene id: 1765967:BW247_RS15305
uniprot id: A0A1P8UKC4
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1765967:BW247 RS11975
gene id: 1765967:BW247_RS11975
uniprot id: A0A1P8UIQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1765967:BW247 RS02640
gene id: 1765967:BW247_RS02640
uniprot id: A0A1P8UE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS03240
gene id: 1765967:BW247_RS03240
uniprot id: A0A1P8UL22
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1765967:BW247 RS01490
gene id: 1765967:BW247_RS01490
uniprot id: A0A1P8UKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1765967:BW247 RS07570
gene id: 1765967:BW247_RS07570
uniprot id: A0A1P8UGH9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1765967:BW247 RS02770
gene id: 1765967:BW247_RS02770
uniprot id: A0A1P8UEB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1765967:BW247 RS09655
gene id: 1765967:BW247_RS09655
uniprot id: A0A1P8UHM2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1765967:BW247 RS13190
gene id: 1765967:BW247_RS13190
uniprot id: A0A1P8UJA7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1765967:BW247 RS05775
gene id: 1765967:BW247_RS05775
uniprot id: A0A1P8UFT9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1765967:BW247 RS04105
gene id: 1765967:BW247_RS04105
uniprot id: A0A1P8UF26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1765967:BW247 RS12795
gene id: 1765967:BW247_RS12795
uniprot id: A0A1P8ULJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1765967:BW247 RS14635
gene id: 1765967:BW247_RS14635
uniprot id: A0A1P8UK01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1765967:BW247 RS06965
gene id: 1765967:BW247_RS06965
uniprot id: A0A1P8UGB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1765967:BW247 RS04140
gene id: 1765967:BW247_RS04140
uniprot id: A0A1P8UEX3
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS09530
gene id: 1765967:BW247_RS09530
uniprot id: A0A1P8UHJ0
names: Subcellular Location Annotation
messages: Cytoplasm

1765967:BW247 RS00370
gene id: 1765967:BW247_RS00370
uniprot id: A0A1P8UD77
names: Similarity
messages: Belongs to the peptidase S41A family.

1765967:BW247 RS07005
gene id: 1765967:BW247_RS07005
uniprot id: A0A1P8UGA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1765967:BW247 RS16085
gene id: 1765967:BW247_RS16085
uniprot id: A0A1P8UKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1765967:BW247 RS13120
gene id: 1765967:BW247_RS13120
uniprot id: A0A1P8UJD7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1765967:BW247 RS11765
gene id: 1765967:BW247_RS11765
uniprot id: A0A1P8UIN0
names: Similarity
messages: Belongs to the universal stress protein A family.

1765967:BW247 RS08775
gene id: 1765967:BW247_RS08775
uniprot id: A0A1P8ULB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1765967:BW247 RS10980
gene id: 1765967:BW247_RS10980
uniprot id: A0A1P8UI96
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1765967:BW247 RS13050
gene id: 1765967:BW247_RS13050
uniprot id: A0A1P8UJE0
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1765967:BW247 RS15850
gene id: 1765967:BW247_RS15850
uniprot id: A0A1P8UKN0
names: Similarity
messages: Belongs to the DprA/Smf family.

1765967:BW247 RS01365
gene id: 1765967:BW247_RS01365
uniprot id: A0A1P8UDN9
names: Similarity
messages: Belongs to the GppA/Ppx family.

1765967:BW247 RS01370
gene id: 1765967:BW247_RS01370
uniprot id: A0A1P8UDQ1
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS07175
gene id: 1765967:BW247_RS07175
uniprot id: A0A1P8UGB5
names: Similarity
messages: Belongs to the P(II) protein family.

1765967:BW247 RS15200
gene id: 1765967:BW247_RS15200
uniprot id: A0A1P8UKA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1765967:BW247 RS14625
gene id: 1765967:BW247_RS14625
uniprot id: A0A1P8UK11
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1765967:BW247 RS07235
gene id: 1765967:BW247_RS07235
uniprot id: A0A1P8UGF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1765967:BW247 RS06390
gene id: 1765967:BW247_RS06390
uniprot id: A0A1P8UFY9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1765967:BW247 RS11635
gene id: 1765967:BW247_RS11635
uniprot id: A0A1P8UIJ2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1765967:BW247 RS13030
gene id: 1765967:BW247_RS13030
uniprot id: A0A1P8ULK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1765967:BW247 RS14295
gene id: 1765967:BW247_RS14295
uniprot id: A0A1P8ULM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1765967:BW247 RS13440
gene id: 1765967:BW247_RS13440
uniprot id: A0A1P8UJJ7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1765967:BW247 RS14840
gene id: 1765967:BW247_RS14840
uniprot id: A0A1P8UK39
names: Function
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1765967:BW247 RS14010
gene id: 1765967:BW247_RS14010
uniprot id: A0A1P8UJT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1765967:BW247 RS12495
gene id: 1765967:BW247_RS12495
uniprot id: A0A1P8UJ20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1765967:BW247 RS16010
gene id: 1765967:BW247_RS16010
uniprot id: A0A1P8UKR4
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1765967:BW247 RS05975
gene id: 1765967:BW247_RS05975
uniprot id: A0A1P8UG10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS06985
gene id: 1765967:BW247_RS06985
uniprot id: A0A1P8UGB8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1765967:BW247 RS15505
gene id: 1765967:BW247_RS15505
uniprot id: A0A1P8UKG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1765967:BW247 RS09165
gene id: 1765967:BW247_RS09165
uniprot id: A0A1P8UHD9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1765967:BW247 RS12345
gene id: 1765967:BW247_RS12345
uniprot id: A0A1P8UIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1765967:BW247 RS03700
gene id: 1765967:BW247_RS03700
uniprot id: A0A1P8UEM2
names: Similarity
messages: Belongs to the UPF0229 family.

1765967:BW247 RS01385
gene id: 1765967:BW247_RS01385
uniprot id: A0A1P8UDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS15440
gene id: 1765967:BW247_RS15440
uniprot id: A0A1P8ULT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1765967:BW247 RS04130
gene id: 1765967:BW247_RS04130
uniprot id: A0A1P8UEZ5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1765967:BW247 RS15290
gene id: 1765967:BW247_RS15290
uniprot id: A0A1P8UKB4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1765967:BW247 RS03860
gene id: 1765967:BW247_RS03860
uniprot id: A0A1P8UES8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1765967:BW247 RS10945
gene id: 1765967:BW247_RS10945
uniprot id: A0A1P8UI73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1765967:BW247 RS03520
gene id: 1765967:BW247_RS03520
uniprot id: A0A1P8UEJ1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS12855
gene id: 1765967:BW247_RS12855
uniprot id: A0A1P8UJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1765967:BW247 RS15425
gene id: 1765967:BW247_RS15425
uniprot id: A0A1P8UKE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1765967:BW247 RS09180
gene id: 1765967:BW247_RS09180
uniprot id: A0A1P8UHB3
names: Subcellular Location Annotation
messages: Cell inner membrane

1765967:BW247 RS12660
gene id: 1765967:BW247_RS12660
uniprot id: A0A1P8UJ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1765967:BW247 RS11645
gene id: 1765967:BW247_RS11645
uniprot id: A0A1P8ULH4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1765967:BW247 RS10880
gene id: 1765967:BW247_RS10880
uniprot id: A0A1P8UI76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1765967:BW247 RS12240
gene id: 1765967:BW247_RS12240
uniprot id: A0A1P8UIT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1765967:BW247 RS03225
gene id: 1765967:BW247_RS03225
uniprot id: A0A1P8UKZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1765967:BW247 RS01525
gene id: 1765967:BW247_RS01525
uniprot id: A0A1P8UDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1765967:BW247 RS08380
gene id: 1765967:BW247_RS08380
uniprot id: A0A1P8UGZ1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1765967:BW247 RS12970
gene id: 1765967:BW247_RS12970
uniprot id: A0A1P8UJ65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1765967:BW247 RS08165
gene id: 1765967:BW247_RS08165
uniprot id: A0A1P8UGV6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1765967:BW247 RS00165
gene id: 1765967:BW247_RS00165
uniprot id: A0A1P8UKR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1765967:BW247 RS04445
gene id: 1765967:BW247_RS04445
uniprot id: A0A1P8UF54
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1765967:BW247 RS07290
gene id: 1765967:BW247_RS07290
uniprot id: A0A1P8UGG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1765967:BW247 RS14940
gene id: 1765967:BW247_RS14940
uniprot id: A0A1P8UK61
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1765967:BW247 RS10770
gene id: 1765967:BW247_RS10770
uniprot id: A0A1P8UI50
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1765967:BW247 RS12160
gene id: 1765967:BW247_RS12160
uniprot id: A0A1P8UIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1765967:BW247 RS07245
gene id: 1765967:BW247_RS07245
uniprot id: A0A1P8UGK2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1765967:BW247 RS01245
gene id: 1765967:BW247_RS01245
uniprot id: A0A1P8UDG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1765967:BW247 RS03230
gene id: 1765967:BW247_RS03230
uniprot id: A0A1P8UEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1765967:BW247 RS12755
gene id: 1765967:BW247_RS12755
uniprot id: A0A1P8ULK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1765967:BW247 RS02895
gene id: 1765967:BW247_RS02895
uniprot id: A0A1P8UEE8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS03545
gene id: 1765967:BW247_RS03545
uniprot id: A0A1P8UEJ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1765967:BW247 RS06615
gene id: 1765967:BW247_RS06615
uniprot id: A0A1P8UGB2
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1765967:BW247 RS00315
gene id: 1765967:BW247_RS00315
uniprot id: A0A1P8UD11
names: Similarity
messages: Belongs to the RutC family.

1765967:BW247 RS11000
gene id: 1765967:BW247_RS11000
uniprot id: A0A1P8UI85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1765967:BW247 RS08965
gene id: 1765967:BW247_RS08965
uniprot id: A0A1P8UH84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1765967:BW247 RS04675
gene id: 1765967:BW247_RS04675
uniprot id: A0A1P8UFA1
names: Subcellular Location Annotation
messages: Membrane

1765967:BW247 RS11490
gene id: 1765967:BW247_RS11490
uniprot id: A0A1P8UIH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1765967:BW247 RS06080
gene id: 1765967:BW247_RS06080
uniprot id: A0A1P8UFU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1765967:BW247 RS06345
gene id: 1765967:BW247_RS06345
uniprot id: A0A1P8UG08
names: Similarity
messages: Belongs to the peptidase U62 family.

1765967:BW247 RS02325
gene id: 1765967:BW247_RS02325
uniprot id: A0A1P8UE08
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1765967:BW247 RS02575
gene id: 1765967:BW247_RS02575
uniprot id: A0A1P8UE27
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.