1758689:SGUI RS14905
gene id: 1758689:SGUI_RS14905
uniprot id: A0A1B1NFW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1758689:SGUI RS13175
gene id: 1758689:SGUI_RS13175
uniprot id: A0A1B1NEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1758689:SGUI RS15620
gene id: 1758689:SGUI_RS15620
uniprot id: A0A1B1NG98
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1758689:SGUI RS16210
gene id: 1758689:SGUI_RS16210
uniprot id: A0A1B1NGM3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1758689:SGUI RS06460
gene id: 1758689:SGUI_RS06460
uniprot id: A0A1B1NB61
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1758689:SGUI RS03755
gene id: 1758689:SGUI_RS03755
uniprot id: A0A1B1N9P2
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1758689:SGUI RS14230
gene id: 1758689:SGUI_RS14230
uniprot id: A0A1B1NFN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1758689:SGUI RS11140
gene id: 1758689:SGUI_RS11140
uniprot id: A0A1B1NDT6
names: Similarity
messages: Belongs to the malic enzymes family.

1758689:SGUI RS10295
gene id: 1758689:SGUI_RS10295
uniprot id: A0A1B1NDB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1758689:SGUI RS00925
gene id: 1758689:SGUI_RS00925
uniprot id: A0A1B1N826
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS03590
gene id: 1758689:SGUI_RS03590
uniprot id: A0A1B1N9J4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1758689:SGUI RS12590
gene id: 1758689:SGUI_RS12590
uniprot id: A0A1B1NEK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS14200
gene id: 1758689:SGUI_RS14200
uniprot id: A0A1B1NFI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS06780
gene id: 1758689:SGUI_RS06780
uniprot id: A0A1B1NBD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1758689:SGUI RS02115
gene id: 1758689:SGUI_RS02115
uniprot id: A0A1B1N8Q0
names: Similarity
messages: Belongs to the SufE family.

1758689:SGUI RS00120
gene id: 1758689:SGUI_RS00120
uniprot id: A0A1B1N7L7
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS16130
gene id: 1758689:SGUI_RS16130
uniprot id: A0A1B1NGK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1758689:SGUI RS16835
gene id: 1758689:SGUI_RS16835
uniprot id: A0A1B1NGX1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS11365
gene id: 1758689:SGUI_RS11365
uniprot id: A0A1B1NDV4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1758689:SGUI RS07095
gene id: 1758689:SGUI_RS07095
uniprot id: A0A1B1NBJ6
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS06995
gene id: 1758689:SGUI_RS06995
uniprot id: A0A1B1NBK2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1758689:SGUI RS01480
gene id: 1758689:SGUI_RS01480
uniprot id: A0A1B1N8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS06265
gene id: 1758689:SGUI_RS06265
uniprot id: A0A1B1NB14
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1758689:SGUI RS12005
gene id: 1758689:SGUI_RS12005
uniprot id: A0A1B1NEA4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1758689:SGUI RS08440
gene id: 1758689:SGUI_RS08440
uniprot id: A0A1B1NCA0
names: Similarity
messages: Belongs to the CsoR family.

1758689:SGUI RS16635
gene id: 1758689:SGUI_RS16635
uniprot id: A0A1B1NGS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1758689:SGUI RS08585
gene id: 1758689:SGUI_RS08585
uniprot id: A0A1B1NCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS00645
gene id: 1758689:SGUI_RS00645
uniprot id: A0A1B1N7X5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1758689:SGUI RS01055
gene id: 1758689:SGUI_RS01055
uniprot id: A0A1B1N845
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS04990
gene id: 1758689:SGUI_RS04990
uniprot id: A0A1B1NAA3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS12350
gene id: 1758689:SGUI_RS12350
uniprot id: A0A1B1NEM9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1758689:SGUI RS05530
gene id: 1758689:SGUI_RS05530
uniprot id: A0A1B1NAU2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS15505
gene id: 1758689:SGUI_RS15505
uniprot id: A0A1B1NG87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1758689:SGUI RS01070
gene id: 1758689:SGUI_RS01070
uniprot id: A0A1B1N844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS13960
gene id: 1758689:SGUI_RS13960
uniprot id: A0A1B1NFA6
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1758689:SGUI RS02750
gene id: 1758689:SGUI_RS02750
uniprot id: A0A1B1N929
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1758689:SGUI RS00070
gene id: 1758689:SGUI_RS00070
uniprot id: A0A1B1N7K5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1758689:SGUI RS07880
gene id: 1758689:SGUI_RS07880
uniprot id: A0A1B1NBZ3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1758689:SGUI RS11685
gene id: 1758689:SGUI_RS11685
uniprot id: A0A1B1NE41
names: Similarity
messages: Belongs to the carbamate kinase family.

1758689:SGUI RS10490
gene id: 1758689:SGUI_RS10490
uniprot id: A0A1B1NDM6
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS08575
gene id: 1758689:SGUI_RS08575
uniprot id: A0A1B1NCB9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS00325
gene id: 1758689:SGUI_RS00325
uniprot id: A0A1B1N7Q2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1758689:SGUI RS00010
gene id: 1758689:SGUI_RS00010
uniprot id: A0A1B1N7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS01295
gene id: 1758689:SGUI_RS01295
uniprot id: A0A1B1N8D2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1758689:SGUI RS03345
gene id: 1758689:SGUI_RS03345
uniprot id: A0A1B1N9E5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS05315
gene id: 1758689:SGUI_RS05315
uniprot id: A0A1B1NAI1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1758689:SGUI RS12625
gene id: 1758689:SGUI_RS12625
uniprot id: A0A1B1NEP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1758689:SGUI RS12260
gene id: 1758689:SGUI_RS12260
uniprot id: A0A1B1NEH7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1758689:SGUI RS03760
gene id: 1758689:SGUI_RS03760
uniprot id: A0A1B1N9R9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1758689:SGUI RS11535
gene id: 1758689:SGUI_RS11535
uniprot id: A0A1B1NE14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS13100
gene id: 1758689:SGUI_RS13100
uniprot id: A0A1B1NEW9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1758689:SGUI RS07160
gene id: 1758689:SGUI_RS07160
uniprot id: A0A1B1NBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS00580
gene id: 1758689:SGUI_RS00580
uniprot id: A0A1B1N7V3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1758689:SGUI RS07795
gene id: 1758689:SGUI_RS07795
uniprot id: A0A1B1NBY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1758689:SGUI RS09150
gene id: 1758689:SGUI_RS09150
uniprot id: A0A1B1NCQ7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1758689:SGUI RS14080
gene id: 1758689:SGUI_RS14080
uniprot id: A0A1B1NFD8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1758689:SGUI RS03245
gene id: 1758689:SGUI_RS03245
uniprot id: A0A1B1N9B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS11530
gene id: 1758689:SGUI_RS11530
uniprot id: A0A1B1NE01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1758689:SGUI RS16105
gene id: 1758689:SGUI_RS16105
uniprot id: A0A1B1NGL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1758689:SGUI RS14735
gene id: 1758689:SGUI_RS14735
uniprot id: A0A1B1NFS9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1758689:SGUI RS04410
gene id: 1758689:SGUI_RS04410
uniprot id: A0A1B1NA32
names: Subcellular Location Annotation
messages: Cytoplasm

1758689:SGUI RS02250
gene id: 1758689:SGUI_RS02250
uniprot id: A0A1B1N8T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1758689:SGUI RS10785
gene id: 1758689:SGUI_RS10785
uniprot id: A0A1B1NDL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1758689:SGUI RS15320
gene id: 1758689:SGUI_RS15320
uniprot id: A0A1B1NG32
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1758689:SGUI RS04920
gene id: 1758689:SGUI_RS04920
uniprot id: A0A1B1NAB4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1758689:SGUI RS03965
gene id: 1758689:SGUI_RS03965
uniprot id: A0A1B1N9T2
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1758689:SGUI RS03985
gene id: 1758689:SGUI_RS03985
uniprot id: A0A1B1N9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS12865
gene id: 1758689:SGUI_RS12865
uniprot id: A0A1B1NEQ2
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS07745
gene id: 1758689:SGUI_RS07745
uniprot id: A0A1B1NBX2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1758689:SGUI RS05440
gene id: 1758689:SGUI_RS05440
uniprot id: A0A1B1NAK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1758689:SGUI RS00805
gene id: 1758689:SGUI_RS00805
uniprot id: A0A1B1N7Z9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

1758689:SGUI RS01830
gene id: 1758689:SGUI_RS01830
uniprot id: A0A1B1N8J6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1758689:SGUI RS00935
gene id: 1758689:SGUI_RS00935
uniprot id: A0A1B1N817
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1758689:SGUI RS13800
gene id: 1758689:SGUI_RS13800
uniprot id: A0A1B1NFC2
names: Similarity
messages: Belongs to the group II decarboxylase family.

1758689:SGUI RS15405
gene id: 1758689:SGUI_RS15405
uniprot id: A0A1B1NG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1758689:SGUI RS09805
gene id: 1758689:SGUI_RS09805
uniprot id: A0A1B1ND24
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1758689:SGUI RS14525
gene id: 1758689:SGUI_RS14525
uniprot id: A0A1B1NFS4
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

1758689:SGUI RS16745
gene id: 1758689:SGUI_RS16745
uniprot id: A0A1B1NGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1758689:SGUI RS14750
gene id: 1758689:SGUI_RS14750
uniprot id: A0A1B1NFT7
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS01335
gene id: 1758689:SGUI_RS01335
uniprot id: A0A1B1N897
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1758689:SGUI RS07935
gene id: 1758689:SGUI_RS07935
uniprot id: A0A1B1NBY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1758689:SGUI RS00245
gene id: 1758689:SGUI_RS00245
uniprot id: A0A1B1N7Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1758689:SGUI RS14910
gene id: 1758689:SGUI_RS14910
uniprot id: A0A1B1NFY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1758689:SGUI RS15960
gene id: 1758689:SGUI_RS15960
uniprot id: A0A1B1NGH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1758689:SGUI RS13985
gene id: 1758689:SGUI_RS13985
uniprot id: A0A1B1NFB8
names: Similarity
messages: Belongs to the WXG100 family.

1758689:SGUI RS14945
gene id: 1758689:SGUI_RS14945
uniprot id: A0A1B1NFX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1758689:SGUI RS05695
gene id: 1758689:SGUI_RS05695
uniprot id: A0A1B1NAQ9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1758689:SGUI RS05660
gene id: 1758689:SGUI_RS05660
uniprot id: A0A1B1NAR7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1758689:SGUI RS12240
gene id: 1758689:SGUI_RS12240
uniprot id: A0A1B1NEC8
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS06080
gene id: 1758689:SGUI_RS06080
uniprot id: A0A1B1NAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS08450
gene id: 1758689:SGUI_RS08450
uniprot id: A0A1B1NCB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1758689:SGUI RS01705
gene id: 1758689:SGUI_RS01705
uniprot id: A0A1B1N8G5
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS01300
gene id: 1758689:SGUI_RS01300
uniprot id: A0A1B1N895
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1758689:SGUI RS14420
gene id: 1758689:SGUI_RS14420
uniprot id: A0A1B1NFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS07415
gene id: 1758689:SGUI_RS07415
uniprot id: A0A1B1NBQ5
names: Subcellular Location Annotation
messages: Mitochondrion

1758689:SGUI RS12970
gene id: 1758689:SGUI_RS12970
uniprot id: A0A1B1NEZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1758689:SGUI RS02075
gene id: 1758689:SGUI_RS02075
uniprot id: A0A1B1N8U4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1758689:SGUI RS07205
gene id: 1758689:SGUI_RS07205
uniprot id: A0A1B1NBN9
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS07990
gene id: 1758689:SGUI_RS07990
uniprot id: A0A1B1NBZ6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1758689:SGUI RS07240
gene id: 1758689:SGUI_RS07240
uniprot id: A0A1B1NBN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1758689:SGUI RS15895
gene id: 1758689:SGUI_RS15895
uniprot id: A0A1B1NGI0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1758689:SGUI RS02295
gene id: 1758689:SGUI_RS02295
uniprot id: A0A1B1N8V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1758689:SGUI RS01040
gene id: 1758689:SGUI_RS01040
uniprot id: A0A1B1N850
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1758689:SGUI RS10030
gene id: 1758689:SGUI_RS10030
uniprot id: A0A1B1ND64
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS07255
gene id: 1758689:SGUI_RS07255
uniprot id: A0A1B1NBP9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1758689:SGUI RS11660
gene id: 1758689:SGUI_RS11660
uniprot id: A0A1B1NE21
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS02990
gene id: 1758689:SGUI_RS02990
uniprot id: A0A1B1N9C7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1758689:SGUI RS14690
gene id: 1758689:SGUI_RS14690
uniprot id: A0A1B1NFR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1758689:SGUI RS17660
gene id: 1758689:SGUI_RS17660
uniprot id: A0A1B1NC70
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS15605
gene id: 1758689:SGUI_RS15605
uniprot id: A0A1B1NGB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1758689:SGUI RS07385
gene id: 1758689:SGUI_RS07385
uniprot id: A0A1B1NBN1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1758689:SGUI RS01050
gene id: 1758689:SGUI_RS01050
uniprot id: A0A1B1N841
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS11620
gene id: 1758689:SGUI_RS11620
uniprot id: A0A1B1NE67
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1758689:SGUI RS06360
gene id: 1758689:SGUI_RS06360
uniprot id: A0A1B1NB34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1758689:SGUI RS15210
gene id: 1758689:SGUI_RS15210
uniprot id: A0A1B1NG35
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1758689:SGUI RS02510
gene id: 1758689:SGUI_RS02510
uniprot id: A0A1B1N906
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS13650
gene id: 1758689:SGUI_RS13650
uniprot id: A0A1B1NF89
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1758689:SGUI RS10135
gene id: 1758689:SGUI_RS10135
uniprot id: A0A1B1ND46
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1758689:SGUI RS01305
gene id: 1758689:SGUI_RS01305
uniprot id: A0A1B1N893
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1758689:SGUI RS07195
gene id: 1758689:SGUI_RS07195
uniprot id: A0A1B1NBL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1758689:SGUI RS15425
gene id: 1758689:SGUI_RS15425
uniprot id: A0A1B1NG70
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1758689:SGUI RS10160
gene id: 1758689:SGUI_RS10160
uniprot id: A0A1B1ND87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS02745
gene id: 1758689:SGUI_RS02745
uniprot id: A0A1B1N947
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1758689:SGUI RS15630
gene id: 1758689:SGUI_RS15630
uniprot id: A0A1B1NG91
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS03750
gene id: 1758689:SGUI_RS03750
uniprot id: A0A1B1N9K8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1758689:SGUI RS01195
gene id: 1758689:SGUI_RS01195
uniprot id: A0A1B1N881
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS05470
gene id: 1758689:SGUI_RS05470
uniprot id: A0A1B1NAL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1758689:SGUI RS04325
gene id: 1758689:SGUI_RS04325
uniprot id: A0A1B1NA10
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1758689:SGUI RS16000
gene id: 1758689:SGUI_RS16000
uniprot id: A0A1B1NGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1758689:SGUI RS10190
gene id: 1758689:SGUI_RS10190
uniprot id: A0A1B1ND82
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS10250
gene id: 1758689:SGUI_RS10250
uniprot id: A0A1B1NDB4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1758689:SGUI RS11155
gene id: 1758689:SGUI_RS11155
uniprot id: A0A1B1NDS2
names: Similarity
messages: Belongs to the HIBADH-related family.

1758689:SGUI RS07000
gene id: 1758689:SGUI_RS07000
uniprot id: A0A1B1NBM1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1758689:SGUI RS09950
gene id: 1758689:SGUI_RS09950
uniprot id: A0A1B1ND32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1758689:SGUI RS01310
gene id: 1758689:SGUI_RS01310
uniprot id: A0A1B1N8A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1758689:SGUI RS13965
gene id: 1758689:SGUI_RS13965
uniprot id: A0A1B1NFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1758689:SGUI RS06575
gene id: 1758689:SGUI_RS06575
uniprot id: A0A1B1NB93
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1758689:SGUI RS06065
gene id: 1758689:SGUI_RS06065
uniprot id: A0A1B1NAX5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1758689:SGUI RS00830
gene id: 1758689:SGUI_RS00830
uniprot id: A0A1B1N812
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1758689:SGUI RS10180
gene id: 1758689:SGUI_RS10180
uniprot id: A0A1B1ND58
names: Similarity
messages: Belongs to the YciI family.

1758689:SGUI RS13020
gene id: 1758689:SGUI_RS13020
uniprot id: A0A1B1NF01
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1758689:SGUI RS05215
gene id: 1758689:SGUI_RS05215
uniprot id: A0A1B1NAF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

1758689:SGUI RS01425
gene id: 1758689:SGUI_RS01425
uniprot id: A0A1B1N8B9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS09380
gene id: 1758689:SGUI_RS09380
uniprot id: A0A1B1NCR8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1758689:SGUI RS10325
gene id: 1758689:SGUI_RS10325
uniprot id: A0A1B1NDA6
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1758689:SGUI RS13475
gene id: 1758689:SGUI_RS13475
uniprot id: A0A1B1NF25
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1758689:SGUI RS00200
gene id: 1758689:SGUI_RS00200
uniprot id: A0A1B1N7M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1758689:SGUI RS03890
gene id: 1758689:SGUI_RS03890
uniprot id: A0A1B1N9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS00870
gene id: 1758689:SGUI_RS00870
uniprot id: A0A1B1N802
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS02435
gene id: 1758689:SGUI_RS02435
uniprot id: A0A1B1N8W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS14260
gene id: 1758689:SGUI_RS14260
uniprot id: A0A1B1NFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS01760
gene id: 1758689:SGUI_RS01760
uniprot id: A0A1B1N8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1758689:SGUI RS10875
gene id: 1758689:SGUI_RS10875
uniprot id: A0A1B1NDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1758689:SGUI RS12025
gene id: 1758689:SGUI_RS12025
uniprot id: A0A1B1NEB7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1758689:SGUI RS16090
gene id: 1758689:SGUI_RS16090
uniprot id: A0A1B1NGK7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS18300
gene id: 1758689:SGUI_RS18300
uniprot id: A0A1B1NCC5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1758689:SGUI RS05935
gene id: 1758689:SGUI_RS05935
uniprot id: A0A1B1NAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1758689:SGUI RS14845
gene id: 1758689:SGUI_RS14845
uniprot id: A0A1B1NFU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1758689:SGUI RS12275
gene id: 1758689:SGUI_RS12275
uniprot id: A0A1B1NEL6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1758689:SGUI RS14790
gene id: 1758689:SGUI_RS14790
uniprot id: A0A1B1NFU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1758689:SGUI RS03785
gene id: 1758689:SGUI_RS03785
uniprot id: A0A1B1N9K3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1758689:SGUI RS11120
gene id: 1758689:SGUI_RS11120
uniprot id: A0A1B1NDS9
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

1758689:SGUI RS15995
gene id: 1758689:SGUI_RS15995
uniprot id: A0A1B1NGK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1758689:SGUI RS07450
gene id: 1758689:SGUI_RS07450
uniprot id: A0A1B1NBQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS14940
gene id: 1758689:SGUI_RS14940
uniprot id: A0A1B1NFZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1758689:SGUI RS05850
gene id: 1758689:SGUI_RS05850
uniprot id: A0A1B1NAT8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1758689:SGUI RS03960
gene id: 1758689:SGUI_RS03960
uniprot id: A0A1B1N9R0
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS12080
gene id: 1758689:SGUI_RS12080
uniprot id: A0A1B1NEC5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1758689:SGUI RS04815
gene id: 1758689:SGUI_RS04815
uniprot id: A0A1B1NA82
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS00760
gene id: 1758689:SGUI_RS00760
uniprot id: A0A1B1N7Y3
names: Similarity
messages: Belongs to the Fur family.

1758689:SGUI RS12675
gene id: 1758689:SGUI_RS12675
uniprot id: A0A1B1NEM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS02170
gene id: 1758689:SGUI_RS02170
uniprot id: A0A1B1N8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1758689:SGUI RS14850
gene id: 1758689:SGUI_RS14850
uniprot id: A0A1B1NFV9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1758689:SGUI RS09000
gene id: 1758689:SGUI_RS09000
uniprot id: A0A1B1NCM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS03695
gene id: 1758689:SGUI_RS03695
uniprot id: A0A1B1N9M7
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1758689:SGUI RS10050
gene id: 1758689:SGUI_RS10050
uniprot id: A0A1B1ND54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1758689:SGUI RS01695
gene id: 1758689:SGUI_RS01695
uniprot id: A0A1B1N8L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1758689:SGUI RS06470
gene id: 1758689:SGUI_RS06470
uniprot id: A0A1B1NB56
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS10880
gene id: 1758689:SGUI_RS10880
uniprot id: A0A1B1NDM0
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1758689:SGUI RS15020
gene id: 1758689:SGUI_RS15020
uniprot id: A0A1B1NFY4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1758689:SGUI RS00265
gene id: 1758689:SGUI_RS00265
uniprot id: A0A1B1N7R0
names: Similarity
messages: Belongs to the malate synthase family.

1758689:SGUI RS16845
gene id: 1758689:SGUI_RS16845
uniprot id: A0A1B1NGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1758689:SGUI RS15610
gene id: 1758689:SGUI_RS15610
uniprot id: A0A1B1NGA7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1758689:SGUI RS04215
gene id: 1758689:SGUI_RS04215
uniprot id: A0A1B1N9Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS14770
gene id: 1758689:SGUI_RS14770
uniprot id: A0A1B1NFU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1758689:SGUI RS12770
gene id: 1758689:SGUI_RS12770
uniprot id: A0A1B1NEN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1758689:SGUI RS12845
gene id: 1758689:SGUI_RS12845
uniprot id: A0A1B1NEP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1758689:SGUI RS02885
gene id: 1758689:SGUI_RS02885
uniprot id: A0A1B1N973
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS03990
gene id: 1758689:SGUI_RS03990
uniprot id: A0A1B1N9Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS16095
gene id: 1758689:SGUI_RS16095
uniprot id: A0A1B1NGM1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1758689:SGUI RS11950
gene id: 1758689:SGUI_RS11950
uniprot id: A0A1B1NEG6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1758689:SGUI RS05990
gene id: 1758689:SGUI_RS05990
uniprot id: A0A1B1NAV8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1758689:SGUI RS04490
gene id: 1758689:SGUI_RS04490
uniprot id: A0A1B1NA27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1758689:SGUI RS02205
gene id: 1758689:SGUI_RS02205
uniprot id: A0A1B1N8S2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1758689:SGUI RS13770
gene id: 1758689:SGUI_RS13770
uniprot id: A0A1B1NFC0
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS16750
gene id: 1758689:SGUI_RS16750
uniprot id: A0A1B1NGX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1758689:SGUI RS16850
gene id: 1758689:SGUI_RS16850
uniprot id: A0A1B1NGZ3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1758689:SGUI RS14995
gene id: 1758689:SGUI_RS14995
uniprot id: A0A1B1NFX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1758689:SGUI RS11060
gene id: 1758689:SGUI_RS11060
uniprot id: A0A1B1NDQ2
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS05705
gene id: 1758689:SGUI_RS05705
uniprot id: A0A1B1NAR1
names: Similarity
messages: Belongs to the peptidase M1 family.

1758689:SGUI RS17940
gene id: 1758689:SGUI_RS17940
uniprot id: A0A1B1NA21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1758689:SGUI RS05495
gene id: 1758689:SGUI_RS05495
uniprot id: A0A1B1NAN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS00960
gene id: 1758689:SGUI_RS00960
uniprot id: A0A1B1N834
names: Similarity
messages: Belongs to the peptidase A24 family.

1758689:SGUI RS14885
gene id: 1758689:SGUI_RS14885
uniprot id: A0A1B1NFV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1758689:SGUI RS06625
gene id: 1758689:SGUI_RS06625
uniprot id: A0A1B1NBA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1758689:SGUI RS06640
gene id: 1758689:SGUI_RS06640
uniprot id: A0A1B1NBD2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1758689:SGUI RS08040
gene id: 1758689:SGUI_RS08040
uniprot id: A0A1B1NC53
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1758689:SGUI RS03660
gene id: 1758689:SGUI_RS03660
uniprot id: A0A1B1N9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS13245
gene id: 1758689:SGUI_RS13245
uniprot id: A0A1B1NEX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1758689:SGUI RS16640
gene id: 1758689:SGUI_RS16640
uniprot id: A0A1B1NGU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1758689:SGUI RS00985
gene id: 1758689:SGUI_RS00985
uniprot id: A0A1B1N827
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1758689:SGUI RS06180
gene id: 1758689:SGUI_RS06180
uniprot id: A0A1B1NB13
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1758689:SGUI RS01015
gene id: 1758689:SGUI_RS01015
uniprot id: A0A1B1N839
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS11935
gene id: 1758689:SGUI_RS11935
uniprot id: A0A1B1NE83
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS00060
gene id: 1758689:SGUI_RS00060
uniprot id: A0A1B1N7K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS00360
gene id: 1758689:SGUI_RS00360
uniprot id: A0A1B1N7R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1758689:SGUI RS13260
gene id: 1758689:SGUI_RS13260
uniprot id: A0A1B1NF02
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1758689:SGUI RS09575
gene id: 1758689:SGUI_RS09575
uniprot id: A0A1B1NCW6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1758689:SGUI RS00400
gene id: 1758689:SGUI_RS00400
uniprot id: A0A1B1N7V9
names: Similarity
messages: Belongs to the Fur family.

1758689:SGUI RS15025
gene id: 1758689:SGUI_RS15025
uniprot id: A0A1B1NFZ4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1758689:SGUI RS06925
gene id: 1758689:SGUI_RS06925
uniprot id: A0A1B1NBH7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1758689:SGUI RS01805
gene id: 1758689:SGUI_RS01805
uniprot id: A0A1B1N8I4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1758689:SGUI RS07725
gene id: 1758689:SGUI_RS07725
uniprot id: A0A1B1NBW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1758689:SGUI RS13645
gene id: 1758689:SGUI_RS13645
uniprot id: A0A1B1NF70
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1758689:SGUI RS14560
gene id: 1758689:SGUI_RS14560
uniprot id: A0A1B1NFQ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1758689:SGUI RS03260
gene id: 1758689:SGUI_RS03260
uniprot id: A0A1B1N9B3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1758689:SGUI RS05290
gene id: 1758689:SGUI_RS05290
uniprot id: A0A1B1NAK9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1758689:SGUI RS03115
gene id: 1758689:SGUI_RS03115
uniprot id: A0A1B1N9A7
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1758689:SGUI RS16480
gene id: 1758689:SGUI_RS16480
uniprot id: A0A1B1NGT1
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS03180
gene id: 1758689:SGUI_RS03180
uniprot id: A0A1B1N9A5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1758689:SGUI RS14890
gene id: 1758689:SGUI_RS14890
uniprot id: A0A1B1NFX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1758689:SGUI RS09760
gene id: 1758689:SGUI_RS09760
uniprot id: A0A1B1ND11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS14225
gene id: 1758689:SGUI_RS14225
uniprot id: A0A1B1NFG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS15340
gene id: 1758689:SGUI_RS15340
uniprot id: A0A1B1NG42
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1758689:SGUI RS02725
gene id: 1758689:SGUI_RS02725
uniprot id: A0A1B1N957
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1758689:SGUI RS07090
gene id: 1758689:SGUI_RS07090
uniprot id: A0A1B1NBK5
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS03530
gene id: 1758689:SGUI_RS03530
uniprot id: A0A1B1N9H5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1758689:SGUI RS16065
gene id: 1758689:SGUI_RS16065
uniprot id: A0A1B1NGJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1758689:SGUI RS14930
gene id: 1758689:SGUI_RS14930
uniprot id: A0A1B1NFX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1758689:SGUI RS11380
gene id: 1758689:SGUI_RS11380
uniprot id: A0A1B1NE17
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1758689:SGUI RS02195
gene id: 1758689:SGUI_RS02195
uniprot id: A0A1B1N8T9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1758689:SGUI RS01145
gene id: 1758689:SGUI_RS01145
uniprot id: A0A1B1N8A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1758689:SGUI RS09285
gene id: 1758689:SGUI_RS09285
uniprot id: A0A1B1NCV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1758689:SGUI RS18290
gene id: 1758689:SGUI_RS18290
uniprot id: A0A1B1N9A0
names: Subcellular Location Annotation
messages: Cytoplasm

1758689:SGUI RS02330
gene id: 1758689:SGUI_RS02330
uniprot id: A0A1B1N8Z9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS05235
gene id: 1758689:SGUI_RS05235
uniprot id: A0A1B1NAG1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1758689:SGUI RS04035
gene id: 1758689:SGUI_RS04035
uniprot id: A0A1B1N9R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1758689:SGUI RS14210
gene id: 1758689:SGUI_RS14210
uniprot id: A0A1B1NFH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS15695
gene id: 1758689:SGUI_RS15695
uniprot id: A0A1B1NGC1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS04025
gene id: 1758689:SGUI_RS04025
uniprot id: A0A1B1N9U6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1758689:SGUI RS05960
gene id: 1758689:SGUI_RS05960
uniprot id: A0A1B1NAY3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1758689:SGUI RS11675
gene id: 1758689:SGUI_RS11675
uniprot id: A0A1B1NE30
names: Similarity
messages: Belongs to the YciI family.

1758689:SGUI RS16655
gene id: 1758689:SGUI_RS16655
uniprot id: A0A1B1NGX7
names: Similarity
messages: Belongs to the acylphosphatase family.

1758689:SGUI RS11505
gene id: 1758689:SGUI_RS11505
uniprot id: A0A1B1NDZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1758689:SGUI RS11465
gene id: 1758689:SGUI_RS11465
uniprot id: A0A1B1NDX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1758689:SGUI RS06920
gene id: 1758689:SGUI_RS06920
uniprot id: A0A1B1NBE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1758689:SGUI RS07920
gene id: 1758689:SGUI_RS07920
uniprot id: A0A1B1NC05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1758689:SGUI RS08115
gene id: 1758689:SGUI_RS08115
uniprot id: A0A1B1NC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1758689:SGUI RS09520
gene id: 1758689:SGUI_RS09520
uniprot id: A0A1B1NCV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1758689:SGUI RS06405
gene id: 1758689:SGUI_RS06405
uniprot id: A0A1B1NB52
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1758689:SGUI RS12630
gene id: 1758689:SGUI_RS12630
uniprot id: A0A1B1NEL0
names: Similarity
messages: Belongs to the peptidase S58 family.

1758689:SGUI RS03710
gene id: 1758689:SGUI_RS03710
uniprot id: A0A1B1N9N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1758689:SGUI RS06760
gene id: 1758689:SGUI_RS06760
uniprot id: A0A1B1NBB8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1758689:SGUI RS16830
gene id: 1758689:SGUI_RS16830
uniprot id: A0A1B1NGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1758689:SGUI RS00390
gene id: 1758689:SGUI_RS00390
uniprot id: A0A1B1N7R5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1758689:SGUI RS04945
gene id: 1758689:SGUI_RS04945
uniprot id: A0A1B1NA98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1758689:SGUI RS06580
gene id: 1758689:SGUI_RS06580
uniprot id: A0A1B1NB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1758689:SGUI RS01725
gene id: 1758689:SGUI_RS01725
uniprot id: A0A1B1N8I5
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1758689:SGUI RS03700
gene id: 1758689:SGUI_RS03700
uniprot id: A0A1B1N9J7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1758689:SGUI RS13010
gene id: 1758689:SGUI_RS13010
uniprot id: A0A1B1NEW4
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS14265
gene id: 1758689:SGUI_RS14265
uniprot id: A0A1B1NFI3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1758689:SGUI RS00100
gene id: 1758689:SGUI_RS00100
uniprot id: A0A1B1N7K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1758689:SGUI RS10495
gene id: 1758689:SGUI_RS10495
uniprot id: A0A1B1NDG1
names: Similarity
messages: Belongs to the citrate synthase family.

1758689:SGUI RS14195
gene id: 1758689:SGUI_RS14195
uniprot id: A0A1B1NFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS13105
gene id: 1758689:SGUI_RS13105
uniprot id: A0A1B1NEV0
names: Similarity
messages: Belongs to the pirin family.

1758689:SGUI RS12790
gene id: 1758689:SGUI_RS12790
uniprot id: A0A1B1NEP4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1758689:SGUI RS12050
gene id: 1758689:SGUI_RS12050
uniprot id: A0A1B1NEI2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS02230
gene id: 1758689:SGUI_RS02230
uniprot id: A0A1B1N8X8
names: Similarity
messages: Belongs to the peptidase M18 family.

1758689:SGUI RS06350
gene id: 1758689:SGUI_RS06350
uniprot id: A0A1B1NB36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1758689:SGUI RS07925
gene id: 1758689:SGUI_RS07925
uniprot id: A0A1B1NBZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1758689:SGUI RS07560
gene id: 1758689:SGUI_RS07560
uniprot id: A0A1B1NBY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1758689:SGUI RS04020
gene id: 1758689:SGUI_RS04020
uniprot id: A0A1B1N9Q3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1758689:SGUI RS01100
gene id: 1758689:SGUI_RS01100
uniprot id: A0A1B1N853
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1758689:SGUI RS14620
gene id: 1758689:SGUI_RS14620
uniprot id: A0A1B1NFQ7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1758689:SGUI RS16320
gene id: 1758689:SGUI_RS16320
uniprot id: A0A1B1NGR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1758689:SGUI RS11165
gene id: 1758689:SGUI_RS11165
uniprot id: A0A1B1NDX8
names: Subunit
messages: Homotetramer.

1758689:SGUI RS01380
gene id: 1758689:SGUI_RS01380
uniprot id: A0A1B1N8A4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1758689:SGUI RS11185
gene id: 1758689:SGUI_RS11185
uniprot id: A0A1B1NE16
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS07660
gene id: 1758689:SGUI_RS07660
uniprot id: A0A1B1NBV4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1758689:SGUI RS11480
gene id: 1758689:SGUI_RS11480
uniprot id: A0A1B1NE37
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS15290
gene id: 1758689:SGUI_RS15290
uniprot id: A0A1B1NG30
names: Similarity
messages: Belongs to the citrate synthase family.

1758689:SGUI RS00520
gene id: 1758689:SGUI_RS00520
uniprot id: A0A1B1N7U1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1758689:SGUI RS03275
gene id: 1758689:SGUI_RS03275
uniprot id: A0A1B1N9D6
names: Similarity
messages: Belongs to the YciI family.

1758689:SGUI RS05260
gene id: 1758689:SGUI_RS05260
uniprot id: A0A1B1NAI5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1758689:SGUI RS12620
gene id: 1758689:SGUI_RS12620
uniprot id: A0A1B1NEL3
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1758689:SGUI RS02590
gene id: 1758689:SGUI_RS02590
uniprot id: A0A1B1N908
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1758689:SGUI RS06400
gene id: 1758689:SGUI_RS06400
uniprot id: A0A1B1NB48
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1758689:SGUI RS09730
gene id: 1758689:SGUI_RS09730
uniprot id: A0A1B1NCZ9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS05460
gene id: 1758689:SGUI_RS05460
uniprot id: A0A1B1NAN0
names: Similarity
messages: Belongs to the FPG family.

1758689:SGUI RS02705
gene id: 1758689:SGUI_RS02705
uniprot id: A0A1B1N916
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1758689:SGUI RS02000
gene id: 1758689:SGUI_RS02000
uniprot id: A0A1B1N8M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1758689:SGUI RS04690
gene id: 1758689:SGUI_RS04690
uniprot id: A0A1B1NA83
names: Similarity
messages: Belongs to the TelA family.

1758689:SGUI RS14875
gene id: 1758689:SGUI_RS14875
uniprot id: A0A1B1NFW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1758689:SGUI RS00185
gene id: 1758689:SGUI_RS00185
uniprot id: A0A1B1N7M3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1758689:SGUI RS01150
gene id: 1758689:SGUI_RS01150
uniprot id: A0A1B1N863
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1758689:SGUI RS16575
gene id: 1758689:SGUI_RS16575
uniprot id: A0A1B1NGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1758689:SGUI RS04540
gene id: 1758689:SGUI_RS04540
uniprot id: A0A1B1NA37
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS10080
gene id: 1758689:SGUI_RS10080
uniprot id: A0A1B1NDA5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS11655
gene id: 1758689:SGUI_RS11655
uniprot id: A0A1B1NE15
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1758689:SGUI RS14965
gene id: 1758689:SGUI_RS14965
uniprot id: A0A1B1NFX2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS14475
gene id: 1758689:SGUI_RS14475
uniprot id: A0A1B1NFS0
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS00500
gene id: 1758689:SGUI_RS00500
uniprot id: A0A1B1N7T8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1758689:SGUI RS09525
gene id: 1758689:SGUI_RS09525
uniprot id: A0A1B1NCV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1758689:SGUI RS13035
gene id: 1758689:SGUI_RS13035
uniprot id: A0A1B1NEV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1758689:SGUI RS02165
gene id: 1758689:SGUI_RS02165
uniprot id: A0A1B1N8Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1758689:SGUI RS07265
gene id: 1758689:SGUI_RS07265
uniprot id: A0A1B1NBM4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1758689:SGUI RS06235
gene id: 1758689:SGUI_RS06235
uniprot id: A0A1B1NB21
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1758689:SGUI RS14950
gene id: 1758689:SGUI_RS14950
uniprot id: A0A1B1NFX9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1758689:SGUI RS00235
gene id: 1758689:SGUI_RS00235
uniprot id: A0A1B1N7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1758689:SGUI RS08535
gene id: 1758689:SGUI_RS08535
uniprot id: A0A1B1NCA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1758689:SGUI RS15725
gene id: 1758689:SGUI_RS15725
uniprot id: A0A1B1NGC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1758689:SGUI RS10890
gene id: 1758689:SGUI_RS10890
uniprot id: A0A1B1NDN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1758689:SGUI RS02265
gene id: 1758689:SGUI_RS02265
uniprot id: A0A1B1N8S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1758689:SGUI RS05175
gene id: 1758689:SGUI_RS05175
uniprot id: A0A1B1NAH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1758689:SGUI RS14900
gene id: 1758689:SGUI_RS14900
uniprot id: A0A1B1NFW3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1758689:SGUI RS09195
gene id: 1758689:SGUI_RS09195
uniprot id: A0A1B1NCP9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1758689:SGUI RS11410
gene id: 1758689:SGUI_RS11410
uniprot id: A0A1B1NDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS03330
gene id: 1758689:SGUI_RS03330
uniprot id: A0A1B1N9E7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1758689:SGUI RS15055
gene id: 1758689:SGUI_RS15055
uniprot id: A0A1B1NG15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1758689:SGUI RS17670
gene id: 1758689:SGUI_RS17670
uniprot id: A0A1B1NCJ3
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS05285
gene id: 1758689:SGUI_RS05285
uniprot id: A0A1B1NAH2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1758689:SGUI RS01095
gene id: 1758689:SGUI_RS01095
uniprot id: A0A1B1N891
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1758689:SGUI RS11990
gene id: 1758689:SGUI_RS11990
uniprot id: A0A1B1NEC3
names: Similarity
messages: Belongs to the YciI family.

1758689:SGUI RS06015
gene id: 1758689:SGUI_RS06015
uniprot id: A0A1B1NB28
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS03215
gene id: 1758689:SGUI_RS03215
uniprot id: A0A1B1N9E2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS00130
gene id: 1758689:SGUI_RS00130
uniprot id: A0A1B1N7L1
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1758689:SGUI RS07210
gene id: 1758689:SGUI_RS07210
uniprot id: A0A1B1NBR2
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS06330
gene id: 1758689:SGUI_RS06330
uniprot id: A0A1B1NB41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1758689:SGUI RS01505
gene id: 1758689:SGUI_RS01505
uniprot id: A0A1B1N8C8
names: Similarity
messages: Belongs to the UPF0098 family.

1758689:SGUI RS13905
gene id: 1758689:SGUI_RS13905
uniprot id: A0A1B1NFD6
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS04290
gene id: 1758689:SGUI_RS04290
uniprot id: A0A1B1N9Y9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1758689:SGUI RS09955
gene id: 1758689:SGUI_RS09955
uniprot id: A0A1B1ND12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1758689:SGUI RS14780
gene id: 1758689:SGUI_RS14780
uniprot id: A0A1B1NFU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1758689:SGUI RS09545
gene id: 1758689:SGUI_RS09545
uniprot id: A0A1B1NCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1758689:SGUI RS15015
gene id: 1758689:SGUI_RS15015
uniprot id: A0A1B1NFY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1758689:SGUI RS06990
gene id: 1758689:SGUI_RS06990
uniprot id: A0A1B1NBH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1758689:SGUI RS07695
gene id: 1758689:SGUI_RS07695
uniprot id: A0A1B1NBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS06175
gene id: 1758689:SGUI_RS06175
uniprot id: A0A1B1NAZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1758689:SGUI RS09920
gene id: 1758689:SGUI_RS09920
uniprot id: A0A1B1ND31
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS14470
gene id: 1758689:SGUI_RS14470
uniprot id: A0A1B1NFM1
names: Similarity
messages: Belongs to the UPF0234 family.

1758689:SGUI RS04545
gene id: 1758689:SGUI_RS04545
uniprot id: A0A1B1NA25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1758689:SGUI RS14815
gene id: 1758689:SGUI_RS14815
uniprot id: A0A1B1NFV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1758689:SGUI RS07950
gene id: 1758689:SGUI_RS07950
uniprot id: A0A1B1NC11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1758689:SGUI RS10140
gene id: 1758689:SGUI_RS10140
uniprot id: A0A1B1NDB6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS03860
gene id: 1758689:SGUI_RS03860
uniprot id: A0A1B1N9U1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1758689:SGUI RS10280
gene id: 1758689:SGUI_RS10280
uniprot id: A0A1B1ND80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1758689:SGUI RS02405
gene id: 1758689:SGUI_RS02405
uniprot id: A0A1B1N8V9
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS03610
gene id: 1758689:SGUI_RS03610
uniprot id: A0A1B1N9H6
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1758689:SGUI RS10605
gene id: 1758689:SGUI_RS10605
uniprot id: A0A1B1NDG4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1758689:SGUI RS16735
gene id: 1758689:SGUI_RS16735
uniprot id: A0A1B1NGV0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1758689:SGUI RS06195
gene id: 1758689:SGUI_RS06195
uniprot id: A0A1B1NB37
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1758689:SGUI RS03885
gene id: 1758689:SGUI_RS03885
uniprot id: A0A1B1N9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS00965
gene id: 1758689:SGUI_RS00965
uniprot id: A0A1B1N829
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1758689:SGUI RS12785
gene id: 1758689:SGUI_RS12785
uniprot id: A0A1B1NER5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1758689:SGUI RS09440
gene id: 1758689:SGUI_RS09440
uniprot id: A0A1B1NCY6
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1758689:SGUI RS03355
gene id: 1758689:SGUI_RS03355
uniprot id: A0A1B1N9H0
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1758689:SGUI RS08355
gene id: 1758689:SGUI_RS08355
uniprot id: A0A1B1NCD9
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS13600
gene id: 1758689:SGUI_RS13600
uniprot id: A0A1B1NF84
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1758689:SGUI RS14160
gene id: 1758689:SGUI_RS14160
uniprot id: A0A1B1NFG1
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1758689:SGUI RS07540
gene id: 1758689:SGUI_RS07540
uniprot id: A0A1B1NBV1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1758689:SGUI RS08270
gene id: 1758689:SGUI_RS08270
uniprot id: A0A1B1NC62
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1758689:SGUI RS15635
gene id: 1758689:SGUI_RS15635
uniprot id: A0A1B1NGA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1758689:SGUI RS09485
gene id: 1758689:SGUI_RS09485
uniprot id: A0A1B1NCU0
names: Similarity
messages: Belongs to the universal stress protein A family.

1758689:SGUI RS06865
gene id: 1758689:SGUI_RS06865
uniprot id: A0A1B1NBE2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1758689:SGUI RS13915
gene id: 1758689:SGUI_RS13915
uniprot id: A0A1B1NFA8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1758689:SGUI RS07460
gene id: 1758689:SGUI_RS07460
uniprot id: A0A1B1NBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1758689:SGUI RS00865
gene id: 1758689:SGUI_RS00865
uniprot id: A0A1B1N809
names: Similarity
messages: Belongs to the TlyA family.

1758689:SGUI RS05310
gene id: 1758689:SGUI_RS05310
uniprot id: A0A1B1NAJ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1758689:SGUI RS00355
gene id: 1758689:SGUI_RS00355
uniprot id: A0A1B1N7Q3
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS03715
gene id: 1758689:SGUI_RS03715
uniprot id: A0A1B1N9Q5
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

1758689:SGUI RS00155
gene id: 1758689:SGUI_RS00155
uniprot id: A0A1B1N7M5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1758689:SGUI RS14740
gene id: 1758689:SGUI_RS14740
uniprot id: A0A1B1NFT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1758689:SGUI RS16390
gene id: 1758689:SGUI_RS16390
uniprot id: A0A1B1NGQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1758689:SGUI RS15000
gene id: 1758689:SGUI_RS15000
uniprot id: A0A1B1NFX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1758689:SGUI RS09070
gene id: 1758689:SGUI_RS09070
uniprot id: A0A1B1NCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1758689:SGUI RS15930
gene id: 1758689:SGUI_RS15930
uniprot id: A0A1B1NGG8
names: Similarity
messages: Belongs to the AHA1 family.

1758689:SGUI RS06340
gene id: 1758689:SGUI_RS06340
uniprot id: A0A1B1NB67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1758689:SGUI RS05630
gene id: 1758689:SGUI_RS05630
uniprot id: A0A1B1NAW2
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS00605
gene id: 1758689:SGUI_RS00605
uniprot id: A0A1B1N7Z5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1758689:SGUI RS07175
gene id: 1758689:SGUI_RS07175
uniprot id: A0A1B1NBI9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS16880
gene id: 1758689:SGUI_RS16880
uniprot id: A0A1B1NH14
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1758689:SGUI RS09170
gene id: 1758689:SGUI_RS09170
uniprot id: A0A1B1NCP1
names: Similarity
messages: Belongs to the citrate synthase family.

1758689:SGUI RS13455
gene id: 1758689:SGUI_RS13455
uniprot id: A0A1B1NF19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS05395
gene id: 1758689:SGUI_RS05395
uniprot id: A0A1B1NAK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1758689:SGUI RS09425
gene id: 1758689:SGUI_RS09425
uniprot id: A0A1B1NCT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1758689:SGUI RS10175
gene id: 1758689:SGUI_RS10175
uniprot id: A0A1B1ND73
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1758689:SGUI RS02700
gene id: 1758689:SGUI_RS02700
uniprot id: A0A1B1N938
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1758689:SGUI RS02185
gene id: 1758689:SGUI_RS02185
uniprot id: A0A1B1N8S6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1758689:SGUI RS01075
gene id: 1758689:SGUI_RS01075
uniprot id: A0A1B1N855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS04430
gene id: 1758689:SGUI_RS04430
uniprot id: A0A1B1NA30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1758689:SGUI RS16740
gene id: 1758689:SGUI_RS16740
uniprot id: A0A1B1NGW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1758689:SGUI RS14860
gene id: 1758689:SGUI_RS14860
uniprot id: A0A1B1NFW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1758689:SGUI RS09275
gene id: 1758689:SGUI_RS09275
uniprot id: A0A1B1NCP8
names: Similarity
messages: Belongs to the AHA1 family.

1758689:SGUI RS09765
gene id: 1758689:SGUI_RS09765
uniprot id: A0A1B1ND29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1758689:SGUI RS05900
gene id: 1758689:SGUI_RS05900
uniprot id: A0A1B1NAX3
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS04550
gene id: 1758689:SGUI_RS04550
uniprot id: A0A1B1NA48
names: Similarity
messages: Belongs to the universal stress protein A family.

1758689:SGUI RS14795
gene id: 1758689:SGUI_RS14795
uniprot id: A0A1B1NFU4
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS13695
gene id: 1758689:SGUI_RS13695
uniprot id: A0A1B1NF81
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS16690
gene id: 1758689:SGUI_RS16690
uniprot id: A0A1B1NGV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1758689:SGUI RS10095
gene id: 1758689:SGUI_RS10095
uniprot id: A0A1B1ND88
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1758689:SGUI RS02910
gene id: 1758689:SGUI_RS02910
uniprot id: A0A1B1N984
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1758689:SGUI RS00090
gene id: 1758689:SGUI_RS00090
uniprot id: A0A1B1N7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1758689:SGUI RS14410
gene id: 1758689:SGUI_RS14410
uniprot id: A0A1B1NFM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1758689:SGUI RS05970
gene id: 1758689:SGUI_RS05970
uniprot id: A0A1B1NAV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1758689:SGUI RS05790
gene id: 1758689:SGUI_RS05790
uniprot id: A0A1B1NAV6
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS10970
gene id: 1758689:SGUI_RS10970
uniprot id: A0A1B1NDM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1758689:SGUI RS10985
gene id: 1758689:SGUI_RS10985
uniprot id: A0A1B1NDQ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1758689:SGUI RS14830
gene id: 1758689:SGUI_RS14830
uniprot id: A0A1B1NFV6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1758689:SGUI RS10500
gene id: 1758689:SGUI_RS10500
uniprot id: A0A1B1NDE1
names: Similarity
messages: Belongs to the citrate synthase family.

1758689:SGUI RS00140
gene id: 1758689:SGUI_RS00140
uniprot id: A0A1B1N7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS12660
gene id: 1758689:SGUI_RS12660
uniprot id: A0A1B1NEL1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1758689:SGUI RS13680
gene id: 1758689:SGUI_RS13680
uniprot id: A0A1B1NFE0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1758689:SGUI RS01990
gene id: 1758689:SGUI_RS01990
uniprot id: A0A1B1N8P5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1758689:SGUI RS16760
gene id: 1758689:SGUI_RS16760
uniprot id: A0A1B1NGX8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1758689:SGUI RS06320
gene id: 1758689:SGUI_RS06320
uniprot id: A0A1B1NB30
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1758689:SGUI RS14445
gene id: 1758689:SGUI_RS14445
uniprot id: A0A1B1NFM6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS07380
gene id: 1758689:SGUI_RS07380
uniprot id: A0A1B1NBM7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1758689:SGUI RS13380
gene id: 1758689:SGUI_RS13380
uniprot id: A0A1B1NF60
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1758689:SGUI RS06965
gene id: 1758689:SGUI_RS06965
uniprot id: A0A1B1NBF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1758689:SGUI RS15250
gene id: 1758689:SGUI_RS15250
uniprot id: A0A1B1NG41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS00950
gene id: 1758689:SGUI_RS00950
uniprot id: A0A1B1N819
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1758689:SGUI RS02270
gene id: 1758689:SGUI_RS02270
uniprot id: A0A1B1N8S7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1758689:SGUI RS06030
gene id: 1758689:SGUI_RS06030
uniprot id: A0A1B1NAW7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS05120
gene id: 1758689:SGUI_RS05120
uniprot id: A0A1B1NAC9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1758689:SGUI RS06610
gene id: 1758689:SGUI_RS06610
uniprot id: A0A1B1NB85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS05220
gene id: 1758689:SGUI_RS05220
uniprot id: A0A1B1NAF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS01320
gene id: 1758689:SGUI_RS01320
uniprot id: A0A1B1N892
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS00115
gene id: 1758689:SGUI_RS00115
uniprot id: A0A1B1N7L2
names: Similarity
messages: Belongs to the ribF family.

1758689:SGUI RS11580
gene id: 1758689:SGUI_RS11580
uniprot id: A0A1B1NE11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1758689:SGUI RS06215
gene id: 1758689:SGUI_RS06215
uniprot id: A0A1B1NB05
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1758689:SGUI RS01840
gene id: 1758689:SGUI_RS01840
uniprot id: A0A1B1N8P6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1758689:SGUI RS13950
gene id: 1758689:SGUI_RS13950
uniprot id: A0A1B1NFE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1758689:SGUI RS04350
gene id: 1758689:SGUI_RS04350
uniprot id: A0A1B1N9Z9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1758689:SGUI RS03925
gene id: 1758689:SGUI_RS03925
uniprot id: A0A1B1N9R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1758689:SGUI RS10885
gene id: 1758689:SGUI_RS10885
uniprot id: A0A1B1NDM8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1758689:SGUI RS01030
gene id: 1758689:SGUI_RS01030
uniprot id: A0A1B1N835
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1758689:SGUI RS14110
gene id: 1758689:SGUI_RS14110
uniprot id: A0A1B1NFE9
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS03405
gene id: 1758689:SGUI_RS03405
uniprot id: A0A1B1N9G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1758689:SGUI RS07190
gene id: 1758689:SGUI_RS07190
uniprot id: A0A1B1NBM5
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS06635
gene id: 1758689:SGUI_RS06635
uniprot id: A0A1B1NBA2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1758689:SGUI RS12290
gene id: 1758689:SGUI_RS12290
uniprot id: A0A1B1NED9
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS06900
gene id: 1758689:SGUI_RS06900
uniprot id: A0A1B1NBK1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1758689:SGUI RS06810
gene id: 1758689:SGUI_RS06810
uniprot id: A0A1B1NBC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1758689:SGUI RS08705
gene id: 1758689:SGUI_RS08705
uniprot id: A0A1B1NCE5
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS14855
gene id: 1758689:SGUI_RS14855
uniprot id: A0A1B1NFU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1758689:SGUI RS04995
gene id: 1758689:SGUI_RS04995
uniprot id: A0A1B1NAA9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1758689:SGUI RS00835
gene id: 1758689:SGUI_RS00835
uniprot id: A0A1B1N843
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS02690
gene id: 1758689:SGUI_RS02690
uniprot id: A0A1B1N931
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS16530
gene id: 1758689:SGUI_RS16530
uniprot id: A0A1B1NGT0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1758689:SGUI RS01000
gene id: 1758689:SGUI_RS01000
uniprot id: A0A1B1N828
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1758689:SGUI RS00335
gene id: 1758689:SGUI_RS00335
uniprot id: A0A1B1N7Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1758689:SGUI RS14760
gene id: 1758689:SGUI_RS14760
uniprot id: A0A1B1NFT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1758689:SGUI RS05825
gene id: 1758689:SGUI_RS05825
uniprot id: A0A1B1NAS5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1758689:SGUI RS07595
gene id: 1758689:SGUI_RS07595
uniprot id: A0A1B1NBU3
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS05095
gene id: 1758689:SGUI_RS05095
uniprot id: A0A1B1NAI9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1758689:SGUI RS10590
gene id: 1758689:SGUI_RS10590
uniprot id: A0A1B1NDI8
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS00940
gene id: 1758689:SGUI_RS00940
uniprot id: A0A1B1N832
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1758689:SGUI RS05715
gene id: 1758689:SGUI_RS05715
uniprot id: A0A1B1NAQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1758689:SGUI RS09770
gene id: 1758689:SGUI_RS09770
uniprot id: A0A1B1ND79
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS12575
gene id: 1758689:SGUI_RS12575
uniprot id: A0A1B1NEN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1758689:SGUI RS13825
gene id: 1758689:SGUI_RS13825
uniprot id: A0A1B1NF91
names: Similarity
messages: Belongs to the manganese catalase family.

1758689:SGUI RS15530
gene id: 1758689:SGUI_RS15530
uniprot id: A0A1B1NG86
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1758689:SGUI RS15080
gene id: 1758689:SGUI_RS15080
uniprot id: A0A1B1NFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS00330
gene id: 1758689:SGUI_RS00330
uniprot id: A0A1B1N7R8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1758689:SGUI RS12920
gene id: 1758689:SGUI_RS12920
uniprot id: A0A1B1NEY9
names: Similarity
messages: Belongs to the IMPACT family.

1758689:SGUI RS15010
gene id: 1758689:SGUI_RS15010
uniprot id: A0A1B1NFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1758689:SGUI RS01090
gene id: 1758689:SGUI_RS01090
uniprot id: A0A1B1N861
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1758689:SGUI RS05325
gene id: 1758689:SGUI_RS05325
uniprot id: A0A1B1NAK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1758689:SGUI RS01700
gene id: 1758689:SGUI_RS01700
uniprot id: A0A1B1N8H9
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1758689:SGUI RS11900
gene id: 1758689:SGUI_RS11900
uniprot id: A0A1B1NEF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1758689:SGUI RS02235
gene id: 1758689:SGUI_RS02235
uniprot id: A0A1B1N8U1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1758689:SGUI RS03020
gene id: 1758689:SGUI_RS03020
uniprot id: A0A1B1N9A9
names: Similarity
messages: Belongs to the thymidine kinase family.

1758689:SGUI RS16110
gene id: 1758689:SGUI_RS16110
uniprot id: A0A1B1NGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1758689:SGUI RS07750
gene id: 1758689:SGUI_RS07750
uniprot id: A0A1B1NBW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1758689:SGUI RS13295
gene id: 1758689:SGUI_RS13295
uniprot id: A0A1B1NEY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1758689:SGUI RS00440
gene id: 1758689:SGUI_RS00440
uniprot id: A0A1B1N7S4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1758689:SGUI RS06820
gene id: 1758689:SGUI_RS06820
uniprot id: A0A1B1NBD1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS16695
gene id: 1758689:SGUI_RS16695
uniprot id: A0A1B1NGW3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS07260
gene id: 1758689:SGUI_RS07260
uniprot id: A0A1B1NBS2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1758689:SGUI RS08995
gene id: 1758689:SGUI_RS08995
uniprot id: A0A1B1NCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS12990
gene id: 1758689:SGUI_RS12990
uniprot id: A0A1B1NEU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1758689:SGUI RS07810
gene id: 1758689:SGUI_RS07810
uniprot id: A0A1B1NC32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1758689:SGUI RS15190
gene id: 1758689:SGUI_RS15190
uniprot id: A0A1B1NG10
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1758689:SGUI RS06225
gene id: 1758689:SGUI_RS06225
uniprot id: A0A1B1NB09
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1758689:SGUI RS08325
gene id: 1758689:SGUI_RS08325
uniprot id: A0A1B1NC65
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS02825
gene id: 1758689:SGUI_RS02825
uniprot id: A0A1B1N974
names: Similarity
messages: Belongs to the universal stress protein A family.

1758689:SGUI RS10760
gene id: 1758689:SGUI_RS10760
uniprot id: A0A1B1NDI7
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS10570
gene id: 1758689:SGUI_RS10570
uniprot id: A0A1B1NDG3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1758689:SGUI RS02275
gene id: 1758689:SGUI_RS02275
uniprot id: A0A1B1N8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1758689:SGUI RS05300
gene id: 1758689:SGUI_RS05300
uniprot id: A0A1B1NAH8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1758689:SGUI RS07605
gene id: 1758689:SGUI_RS07605
uniprot id: A0A1B1NBW5
names: Similarity
messages: Belongs to the GSP E family.

1758689:SGUI RS16405
gene id: 1758689:SGUI_RS16405
uniprot id: A0A1B1NGQ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1758689:SGUI RS00825
gene id: 1758689:SGUI_RS00825
uniprot id: A0A1B1N7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1758689:SGUI RS15150
gene id: 1758689:SGUI_RS15150
uniprot id: A0A1B1NG22
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1758689:SGUI RS08010
gene id: 1758689:SGUI_RS08010
uniprot id: A0A1B1NC37
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS00020
gene id: 1758689:SGUI_RS00020
uniprot id: A0A1B1N7H8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS08930
gene id: 1758689:SGUI_RS08930
uniprot id: A0A1B1NCI2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1758689:SGUI RS01085
gene id: 1758689:SGUI_RS01085
uniprot id: A0A1B1N847
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1758689:SGUI RS14095
gene id: 1758689:SGUI_RS14095
uniprot id: A0A1B1NFG0
names: Function
names: Similarity
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1758689:SGUI RS05635
gene id: 1758689:SGUI_RS05635
uniprot id: A0A1B1NAP8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1758689:SGUI RS15045
gene id: 1758689:SGUI_RS15045
uniprot id: A0A1B1NFZ2
names: Similarity
messages: Belongs to the FBPase class 2 family.

1758689:SGUI RS02180
gene id: 1758689:SGUI_RS02180
uniprot id: A0A1B1N8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1758689:SGUI RS14820
gene id: 1758689:SGUI_RS14820
uniprot id: A0A1B1NFV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1758689:SGUI RS02090
gene id: 1758689:SGUI_RS02090
uniprot id: A0A1B1N8R7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1758689:SGUI RS14895
gene id: 1758689:SGUI_RS14895
uniprot id: A0A1B1NFW1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1758689:SGUI RS15110
gene id: 1758689:SGUI_RS15110
uniprot id: A0A1B1NG09
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS09720
gene id: 1758689:SGUI_RS09720
uniprot id: A0A1B1ND62
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1758689:SGUI RS12720
gene id: 1758689:SGUI_RS12720
uniprot id: A0A1B1NEN8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1758689:SGUI RS02005
gene id: 1758689:SGUI_RS02005
uniprot id: A0A1B1N8Q1
names: Similarity
messages: Belongs to the UPF0749 family.

1758689:SGUI RS09590
gene id: 1758689:SGUI_RS09590
uniprot id: A0A1B1ND13
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS06790
gene id: 1758689:SGUI_RS06790
uniprot id: A0A1B1NBF4
names: Similarity
messages: Belongs to the PspA/IM30 family.

1758689:SGUI RS06615
gene id: 1758689:SGUI_RS06615
uniprot id: A0A1B1NB83
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS18270
gene id: 1758689:SGUI_RS18270
uniprot id: A0A1B1NB70
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1758689:SGUI RS07985
gene id: 1758689:SGUI_RS07985
uniprot id: A0A1B1NC01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1758689:SGUI RS08590
gene id: 1758689:SGUI_RS08590
uniprot id: A0A1B1NC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS12140
gene id: 1758689:SGUI_RS12140
uniprot id: A0A1B1NEB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1758689:SGUI RS01915
gene id: 1758689:SGUI_RS01915
uniprot id: A0A1B1N8L2
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS14775
gene id: 1758689:SGUI_RS14775
uniprot id: A0A1B1NFU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1758689:SGUI RS08940
gene id: 1758689:SGUI_RS08940
uniprot id: A0A1B1NCN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1758689:SGUI RS06385
gene id: 1758689:SGUI_RS06385
uniprot id: A0A1B1NB47
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS04340
gene id: 1758689:SGUI_RS04340
uniprot id: A0A1B1N9Y7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1758689:SGUI RS05025
gene id: 1758689:SGUI_RS05025
uniprot id: A0A1B1NAE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1758689:SGUI RS00810
gene id: 1758689:SGUI_RS00810
uniprot id: A0A1B1N7Z3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1758689:SGUI RS07085
gene id: 1758689:SGUI_RS07085
uniprot id: A0A1B1NBH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1758689:SGUI RS09675
gene id: 1758689:SGUI_RS09675
uniprot id: A0A1B1NCY8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1758689:SGUI RS01945
gene id: 1758689:SGUI_RS01945
uniprot id: A0A1B1N8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS04860
gene id: 1758689:SGUI_RS04860
uniprot id: A0A1B1NA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS13040
gene id: 1758689:SGUI_RS13040
uniprot id: A0A1B1NET6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS11315
gene id: 1758689:SGUI_RS11315
uniprot id: A0A1B1NDV3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS10200
gene id: 1758689:SGUI_RS10200
uniprot id: A0A1B1NDA4
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS00915
gene id: 1758689:SGUI_RS00915
uniprot id: A0A1B1N818
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1758689:SGUI RS16705
gene id: 1758689:SGUI_RS16705
uniprot id: A0A1B1NGY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1758689:SGUI RS03930
gene id: 1758689:SGUI_RS03930
uniprot id: A0A1B1N9Q4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1758689:SGUI RS16070
gene id: 1758689:SGUI_RS16070
uniprot id: A0A1B1NGJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS08735
gene id: 1758689:SGUI_RS08735
uniprot id: A0A1B1NCE6
names: Similarity
messages: Belongs to the FPG family.

1758689:SGUI RS18310
gene id: 1758689:SGUI_RS18310
uniprot id: A0A1B1NF30
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1758689:SGUI RS13170
gene id: 1758689:SGUI_RS13170
uniprot id: A0A1B1NEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1758689:SGUI RS17635
gene id: 1758689:SGUI_RS17635
uniprot id: A0A1B1NB23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1758689:SGUI RS05075
gene id: 1758689:SGUI_RS05075
uniprot id: A0A1B1NAG2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1758689:SGUI RS00385
gene id: 1758689:SGUI_RS00385
uniprot id: A0A1B1N7R3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1758689:SGUI RS04485
gene id: 1758689:SGUI_RS04485
uniprot id: A0A1B1NA72
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS02190
gene id: 1758689:SGUI_RS02190
uniprot id: A0A1B1N8R4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1758689:SGUI RS14755
gene id: 1758689:SGUI_RS14755
uniprot id: A0A1B1NFU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1758689:SGUI RS02710
gene id: 1758689:SGUI_RS02710
uniprot id: A0A1B1N948
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1758689:SGUI RS10345
gene id: 1758689:SGUI_RS10345
uniprot id: A0A1B1NDD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1758689:SGUI RS00755
gene id: 1758689:SGUI_RS00755
uniprot id: A0A1B1N7Y4
names: Similarity
messages: Belongs to the catalase family.

1758689:SGUI RS06345
gene id: 1758689:SGUI_RS06345
uniprot id: A0A1B1NB87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1758689:SGUI RS04700
gene id: 1758689:SGUI_RS04700
uniprot id: A0A1B1NA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1758689:SGUI RS07685
gene id: 1758689:SGUI_RS07685
uniprot id: A0A1B1NBT8
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS06510
gene id: 1758689:SGUI_RS06510
uniprot id: A0A1B1NB71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1758689:SGUI RS13235
gene id: 1758689:SGUI_RS13235
uniprot id: A0A1B1NEW7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1758689:SGUI RS12200
gene id: 1758689:SGUI_RS12200
uniprot id: A0A1B1NEA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1758689:SGUI RS15400
gene id: 1758689:SGUI_RS15400
uniprot id: A0A1B1NG64
names: Similarity
messages: Belongs to the DEAD box helicase family.

1758689:SGUI RS15580
gene id: 1758689:SGUI_RS15580
uniprot id: A0A1B1NG82
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS11125
gene id: 1758689:SGUI_RS11125
uniprot id: A0A1B1NDT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1758689:SGUI RS06110
gene id: 1758689:SGUI_RS06110
uniprot id: A0A1B1NAY5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1758689:SGUI RS14440
gene id: 1758689:SGUI_RS14440
uniprot id: A0A1B1NFM9
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS02965
gene id: 1758689:SGUI_RS02965
uniprot id: A0A1B1N960
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1758689:SGUI RS08830
gene id: 1758689:SGUI_RS08830
uniprot id: A0A1B1NCG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS14655
gene id: 1758689:SGUI_RS14655
uniprot id: A0A1B1NFR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1758689:SGUI RS11280
gene id: 1758689:SGUI_RS11280
uniprot id: A0A1B1NDV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1758689:SGUI RS15600
gene id: 1758689:SGUI_RS15600
uniprot id: A0A1B1NGA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1758689:SGUI RS16810
gene id: 1758689:SGUI_RS16810
uniprot id: A0A1B1NGY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1758689:SGUI RS00780
gene id: 1758689:SGUI_RS00780
uniprot id: A0A1B1N803
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1758689:SGUI RS06335
gene id: 1758689:SGUI_RS06335
uniprot id: A0A1B1NB39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1758689:SGUI RS14460
gene id: 1758689:SGUI_RS14460
uniprot id: A0A1B1NFN2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1758689:SGUI RS11095
gene id: 1758689:SGUI_RS11095
uniprot id: A0A1B1NDS7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1758689:SGUI RS11325
gene id: 1758689:SGUI_RS11325
uniprot id: A0A1B1NE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS12580
gene id: 1758689:SGUI_RS12580
uniprot id: A0A1B1NEJ9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1758689:SGUI RS11305
gene id: 1758689:SGUI_RS11305
uniprot id: A0A1B1NDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1758689:SGUI RS12095
gene id: 1758689:SGUI_RS12095
uniprot id: A0A1B1NEE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1758689:SGUI RS12945
gene id: 1758689:SGUI_RS12945
uniprot id: A0A1B1NER6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1758689:SGUI RS02640
gene id: 1758689:SGUI_RS02640
uniprot id: A0A1B1N919
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1758689:SGUI RS09630
gene id: 1758689:SGUI_RS09630
uniprot id: A0A1B1NCX7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1758689:SGUI RS01815
gene id: 1758689:SGUI_RS01815
uniprot id: A0A1B1N8J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS15790
gene id: 1758689:SGUI_RS15790
uniprot id: A0A1B1NGG0
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS14870
gene id: 1758689:SGUI_RS14870
uniprot id: A0A1B1NFW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1758689:SGUI RS03645
gene id: 1758689:SGUI_RS03645
uniprot id: A0A1B1N9H3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS07395
gene id: 1758689:SGUI_RS07395
uniprot id: A0A1B1NBQ3
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS01270
gene id: 1758689:SGUI_RS01270
uniprot id: A0A1B1N883
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1758689:SGUI RS17645
gene id: 1758689:SGUI_RS17645
uniprot id: A0A1B1NBJ1
names: Similarity
messages: Belongs to the peptidase C40 family.

1758689:SGUI RS08855
gene id: 1758689:SGUI_RS08855
uniprot id: A0A1B1NCJ5
names: Similarity
messages: Belongs to the CFA/CMAS family.

1758689:SGUI RS04500
gene id: 1758689:SGUI_RS04500
uniprot id: A0A1B1NA40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1758689:SGUI RS10565
gene id: 1758689:SGUI_RS10565
uniprot id: A0A1B1NDK5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1758689:SGUI RS02685
gene id: 1758689:SGUI_RS02685
uniprot id: A0A1B1N963
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

1758689:SGUI RS11995
gene id: 1758689:SGUI_RS11995
uniprot id: A0A1B1NEA3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1758689:SGUI RS04475
gene id: 1758689:SGUI_RS04475
uniprot id: A0A1B1NA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1758689:SGUI RS14840
gene id: 1758689:SGUI_RS14840
uniprot id: A0A1B1NFV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1758689:SGUI RS06365
gene id: 1758689:SGUI_RS06365
uniprot id: A0A1B1NB38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1758689:SGUI RS16230
gene id: 1758689:SGUI_RS16230
uniprot id: A0A1B1NGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1758689:SGUI RS09740
gene id: 1758689:SGUI_RS09740
uniprot id: A0A1B1NCZ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1758689:SGUI RS00905
gene id: 1758689:SGUI_RS00905
uniprot id: A0A1B1N811
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS01285
gene id: 1758689:SGUI_RS01285
uniprot id: A0A1B1N887
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1758689:SGUI RS01875
gene id: 1758689:SGUI_RS01875
uniprot id: A0A1B1N8K4
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS08895
gene id: 1758689:SGUI_RS08895
uniprot id: A0A1B1NCI5
names: Similarity
messages: Belongs to the CFA/CMAS family.

1758689:SGUI RS04590
gene id: 1758689:SGUI_RS04590
uniprot id: A0A1B1NA36
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS15890
gene id: 1758689:SGUI_RS15890
uniprot id: A0A1B1NGG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1758689:SGUI RS07320
gene id: 1758689:SGUI_RS07320
uniprot id: A0A1B1NBM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

1758689:SGUI RS16595
gene id: 1758689:SGUI_RS16595
uniprot id: A0A1B1NGT9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1758689:SGUI RS14535
gene id: 1758689:SGUI_RS14535
uniprot id: A0A1B1NFP2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1758689:SGUI RS13935
gene id: 1758689:SGUI_RS13935
uniprot id: A0A1B1NFH9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1758689:SGUI RS00375
gene id: 1758689:SGUI_RS00375
uniprot id: A0A1B1N7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
messages: Cytoplasm

1758689:SGUI RS07110
gene id: 1758689:SGUI_RS07110
uniprot id: A0A1B1NBP2
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1758689:SGUI RS02095
gene id: 1758689:SGUI_RS02095
uniprot id: A0A1B1N8R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1758689:SGUI RS09990
gene id: 1758689:SGUI_RS09990
uniprot id: A0A1B1ND55
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS16680
gene id: 1758689:SGUI_RS16680
uniprot id: A0A1B1NGU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1758689:SGUI RS14425
gene id: 1758689:SGUI_RS14425
uniprot id: A0A1B1NFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS16660
gene id: 1758689:SGUI_RS16660
uniprot id: A0A1B1NGV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1758689:SGUI RS09985
gene id: 1758689:SGUI_RS09985
uniprot id: A0A1B1NDB8
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS09735
gene id: 1758689:SGUI_RS09735
uniprot id: A0A1B1NCZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1758689:SGUI RS04840
gene id: 1758689:SGUI_RS04840
uniprot id: A0A1B1NA77
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1758689:SGUI RS16770
gene id: 1758689:SGUI_RS16770
uniprot id: A0A1B1NGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1758689:SGUI RS10935
gene id: 1758689:SGUI_RS10935
uniprot id: A0A1B1NDN8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1758689:SGUI RS16825
gene id: 1758689:SGUI_RS16825
uniprot id: A0A1B1NGZ0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1758689:SGUI RS14600
gene id: 1758689:SGUI_RS14600
uniprot id: A0A1B1NFS6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS04310
gene id: 1758689:SGUI_RS04310
uniprot id: A0A1B1NA04
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1758689:SGUI RS09530
gene id: 1758689:SGUI_RS09530
uniprot id: A0A1B1NCV1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1758689:SGUI RS01045
gene id: 1758689:SGUI_RS01045
uniprot id: A0A1B1N880
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1758689:SGUI RS15655
gene id: 1758689:SGUI_RS15655
uniprot id: A0A1B1NGC7
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS07325
gene id: 1758689:SGUI_RS07325
uniprot id: A0A1B1NBM0
names: Similarity
messages: Belongs to the Nth/MutY family.

1758689:SGUI RS09570
gene id: 1758689:SGUI_RS09570
uniprot id: A0A1B1NCW5
names: Similarity
messages: Belongs to the thioredoxin family.

1758689:SGUI RS09895
gene id: 1758689:SGUI_RS09895
uniprot id: A0A1B1ND27
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1758689:SGUI RS09175
gene id: 1758689:SGUI_RS09175
uniprot id: A0A1B1NCN2
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1758689:SGUI RS00165
gene id: 1758689:SGUI_RS00165
uniprot id: A0A1B1N7M4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1758689:SGUI RS02030
gene id: 1758689:SGUI_RS02030
uniprot id: A0A1B1N8P8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1758689:SGUI RS01010
gene id: 1758689:SGUI_RS01010
uniprot id: A0A1B1N838
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1758689:SGUI RS05785
gene id: 1758689:SGUI_RS05785
uniprot id: A0A1B1NAS3
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS14920
gene id: 1758689:SGUI_RS14920
uniprot id: A0A1B1NFY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1758689:SGUI RS02790
gene id: 1758689:SGUI_RS02790
uniprot id: A0A1B1N932
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1758689:SGUI RS03535
gene id: 1758689:SGUI_RS03535
uniprot id: A0A1B1N9H2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1758689:SGUI RS02210
gene id: 1758689:SGUI_RS02210
uniprot id: A0A1B1N8U2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1758689:SGUI RS14240
gene id: 1758689:SGUI_RS14240
uniprot id: A0A1B1NFI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS16160
gene id: 1758689:SGUI_RS16160
uniprot id: A0A1B1NGL3
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS01670
gene id: 1758689:SGUI_RS01670
uniprot id: A0A1B1N8F9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1758689:SGUI RS02850
gene id: 1758689:SGUI_RS02850
uniprot id: A0A1B1N950
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1758689:SGUI RS05160
gene id: 1758689:SGUI_RS05160
uniprot id: A0A1B1NAG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1758689:SGUI RS09515
gene id: 1758689:SGUI_RS09515
uniprot id: A0A1B1NCW8
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1758689:SGUI RS10755
gene id: 1758689:SGUI_RS10755
uniprot id: A0A1B1NDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS15680
gene id: 1758689:SGUI_RS15680
uniprot id: A0A1B1NGC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1758689:SGUI RS09750
gene id: 1758689:SGUI_RS09750
uniprot id: A0A1B1ND45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS00945
gene id: 1758689:SGUI_RS00945
uniprot id: A0A1B1N859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1758689:SGUI RS14340
gene id: 1758689:SGUI_RS14340
uniprot id: A0A1B1NFK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1758689:SGUI RS11760
gene id: 1758689:SGUI_RS11760
uniprot id: A0A1B1NE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1758689:SGUI RS18305
gene id: 1758689:SGUI_RS18305
uniprot id: A0A1B1NCM3
names: Similarity
messages: Belongs to the peptidase S8 family.

1758689:SGUI RS04455
gene id: 1758689:SGUI_RS04455
uniprot id: A0A1B1NA20
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1758689:SGUI RS04495
gene id: 1758689:SGUI_RS04495
uniprot id: A0A1B1NA13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS10620
gene id: 1758689:SGUI_RS10620
uniprot id: A0A1B1NDH1
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS12700
gene id: 1758689:SGUI_RS12700
uniprot id: A0A1B1NEM4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS06740
gene id: 1758689:SGUI_RS06740
uniprot id: A0A1B1NBC1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1758689:SGUI RS06145
gene id: 1758689:SGUI_RS06145
uniprot id: A0A1B1NAZ6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1758689:SGUI RS05320
gene id: 1758689:SGUI_RS05320
uniprot id: A0A1B1NAH4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS00895
gene id: 1758689:SGUI_RS00895
uniprot id: A0A1B1N852
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS13420
gene id: 1758689:SGUI_RS13420
uniprot id: A0A1B1NF38
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1758689:SGUI RS05525
gene id: 1758689:SGUI_RS05525
uniprot id: A0A1B1NAQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1758689:SGUI RS04865
gene id: 1758689:SGUI_RS04865
uniprot id: A0A1B1NA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS16890
gene id: 1758689:SGUI_RS16890
uniprot id: A0A1B1NGZ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS04465
gene id: 1758689:SGUI_RS04465
uniprot id: A0A1B1NA39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1758689:SGUI RS05445
gene id: 1758689:SGUI_RS05445
uniprot id: A0A1B1NAM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1758689:SGUI RS07505
gene id: 1758689:SGUI_RS07505
uniprot id: A0A1B1NBU4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1758689:SGUI RS03000
gene id: 1758689:SGUI_RS03000
uniprot id: A0A1B1N975
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1758689:SGUI RS16015
gene id: 1758689:SGUI_RS16015
uniprot id: A0A1B1NGI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1758689:SGUI RS02845
gene id: 1758689:SGUI_RS02845
uniprot id: A0A1B1N967
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS12690
gene id: 1758689:SGUI_RS12690
uniprot id: A0A1B1NEU4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1758689:SGUI RS01720
gene id: 1758689:SGUI_RS01720
uniprot id: A0A1B1N8G9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1758689:SGUI RS01735
gene id: 1758689:SGUI_RS01735
uniprot id: A0A1B1N8H2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1758689:SGUI RS08410
gene id: 1758689:SGUI_RS08410
uniprot id: A0A1B1NC99
names: Similarity
messages: Belongs to the barstar family.

1758689:SGUI RS04810
gene id: 1758689:SGUI_RS04810
uniprot id: A0A1B1NA95
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS07105
gene id: 1758689:SGUI_RS07105
uniprot id: A0A1B1NBM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1758689:SGUI RS07250
gene id: 1758689:SGUI_RS07250
uniprot id: A0A1B1NBL7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1758689:SGUI RS03795
gene id: 1758689:SGUI_RS03795
uniprot id: A0A1B1N9L8
names: Similarity
messages: Belongs to the TPP enzyme family.

1758689:SGUI RS13335
gene id: 1758689:SGUI_RS13335
uniprot id: A0A1B1NEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1758689:SGUI RS07940
gene id: 1758689:SGUI_RS07940
uniprot id: A0A1B1NBY5
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS04460
gene id: 1758689:SGUI_RS04460
uniprot id: A0A1B1N9Z3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1758689:SGUI RS13470
gene id: 1758689:SGUI_RS13470
uniprot id: A0A1B1NF82
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1758689:SGUI RS00220
gene id: 1758689:SGUI_RS00220
uniprot id: A0A1B1N7N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1758689:SGUI RS15615
gene id: 1758689:SGUI_RS15615
uniprot id: A0A1B1NG94
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1758689:SGUI RS00105
gene id: 1758689:SGUI_RS00105
uniprot id: A0A1B1N7L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1758689:SGUI RS09555
gene id: 1758689:SGUI_RS09555
uniprot id: A0A1B1NCY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1758689:SGUI RS05225
gene id: 1758689:SGUI_RS05225
uniprot id: A0A1B1NAI7
names: Similarity
messages: Belongs to the PGI/PMI family.

1758689:SGUI RS02675
gene id: 1758689:SGUI_RS02675
uniprot id: A0A1B1N903
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1758689:SGUI RS05920
gene id: 1758689:SGUI_RS05920
uniprot id: A0A1B1NAU9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1758689:SGUI RS16895
gene id: 1758689:SGUI_RS16895
uniprot id: A0A1B1NGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1758689:SGUI RS02255
gene id: 1758689:SGUI_RS02255
uniprot id: A0A1B1N8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1758689:SGUI RS01445
gene id: 1758689:SGUI_RS01445
uniprot id: A0A1B1N8G8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1758689:SGUI RS11510
gene id: 1758689:SGUI_RS11510
uniprot id: A0A1B1NDY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1758689:SGUI RS14100
gene id: 1758689:SGUI_RS14100
uniprot id: A0A1B1NFG3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS13280
gene id: 1758689:SGUI_RS13280
uniprot id: A0A1B1NF16
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1758689:SGUI RS13620
gene id: 1758689:SGUI_RS13620
uniprot id: A0A1B1NF87
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1758689:SGUI RS14245
gene id: 1758689:SGUI_RS14245
uniprot id: A0A1B1NFJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1758689:SGUI RS16165
gene id: 1758689:SGUI_RS16165
uniprot id: A0A1B1NGL7
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS15640
gene id: 1758689:SGUI_RS15640
uniprot id: A0A1B1NGB0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1758689:SGUI RS08925
gene id: 1758689:SGUI_RS08925
uniprot id: A0A1B1NCI9
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS06115
gene id: 1758689:SGUI_RS06115
uniprot id: A0A1B1NAY9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1758689:SGUI RS06680
gene id: 1758689:SGUI_RS06680
uniprot id: A0A1B1NBB4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1758689:SGUI RS01385
gene id: 1758689:SGUI_RS01385
uniprot id: A0A1B1N8A7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1758689:SGUI RS00575
gene id: 1758689:SGUI_RS00575
uniprot id: A0A1B1N7V1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1758689:SGUI RS02480
gene id: 1758689:SGUI_RS02480
uniprot id: A0A1B1N8Y8
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS03955
gene id: 1758689:SGUI_RS03955
uniprot id: A0A1B1N9R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS04765
gene id: 1758689:SGUI_RS04765
uniprot id: A0A1B1NA74
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS10915
gene id: 1758689:SGUI_RS10915
uniprot id: A0A1B1NDM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1758689:SGUI RS09650
gene id: 1758689:SGUI_RS09650
uniprot id: A0A1B1NCY1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1758689:SGUI RS08330
gene id: 1758689:SGUI_RS08330
uniprot id: A0A1B1NC50
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS00970
gene id: 1758689:SGUI_RS00970
uniprot id: A0A1B1N823
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1758689:SGUI RS02560
gene id: 1758689:SGUI_RS02560
uniprot id: A0A1B1N8Z0
names: Similarity
messages: Belongs to the peptidase S1B family.

1758689:SGUI RS08825
gene id: 1758689:SGUI_RS08825
uniprot id: A0A1B1NCH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS08320
gene id: 1758689:SGUI_RS08320
uniprot id: A0A1B1NC72
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1758689:SGUI RS14220
gene id: 1758689:SGUI_RS14220
uniprot id: A0A1B1NFJ0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1758689:SGUI RS12975
gene id: 1758689:SGUI_RS12975
uniprot id: A0A1B1NES4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1758689:SGUI RS04450
gene id: 1758689:SGUI_RS04450
uniprot id: A0A1B1NA26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1758689:SGUI RS06355
gene id: 1758689:SGUI_RS06355
uniprot id: A0A1B1NB42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1758689:SGUI RS13685
gene id: 1758689:SGUI_RS13685
uniprot id: A0A1B1NF67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1758689:SGUI RS13410
gene id: 1758689:SGUI_RS13410
uniprot id: A0A1B1NF23
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1758689:SGUI RS04445
gene id: 1758689:SGUI_RS04445
uniprot id: A0A1B1NA07
names: Similarity
messages: Belongs to the YggT family.

1758689:SGUI RS02125
gene id: 1758689:SGUI_RS02125
uniprot id: A0A1B1N8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1758689:SGUI RS04380
gene id: 1758689:SGUI_RS04380
uniprot id: A0A1B1NA52
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1758689:SGUI RS01965
gene id: 1758689:SGUI_RS01965
uniprot id: A0A1B1N8L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1758689:SGUI RS04515
gene id: 1758689:SGUI_RS04515
uniprot id: A0A1B1NA51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1758689:SGUI RS02695
gene id: 1758689:SGUI_RS02695
uniprot id: A0A1B1N912
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1758689:SGUI RS06305
gene id: 1758689:SGUI_RS06305
uniprot id: A0A1B1NB32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1758689:SGUI RS09475
gene id: 1758689:SGUI_RS09475
uniprot id: A0A1B1NCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1758689:SGUI RS15950
gene id: 1758689:SGUI_RS15950
uniprot id: A0A1B1NGH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1758689:SGUI RS13980
gene id: 1758689:SGUI_RS13980
uniprot id: A0A1B1NFI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1758689:SGUI RS15260
gene id: 1758689:SGUI_RS15260
uniprot id: A0A1B1NG47
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1758689:SGUI RS08075
gene id: 1758689:SGUI_RS08075
uniprot id: A0A1B1NC26
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1758689:SGUI RS06035
gene id: 1758689:SGUI_RS06035
uniprot id: A0A1B1NAX0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1758689:SGUI RS04335
gene id: 1758689:SGUI_RS04335
uniprot id: A0A1B1NA00
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS01365
gene id: 1758689:SGUI_RS01365
uniprot id: A0A1B1N8B1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1758689:SGUI RS07680
gene id: 1758689:SGUI_RS07680
uniprot id: A0A1B1NBT5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1758689:SGUI RS08970
gene id: 1758689:SGUI_RS08970
uniprot id: A0A1B1NCJ8
names: Similarity
messages: Belongs to the FPG family.

1758689:SGUI RS04825
gene id: 1758689:SGUI_RS04825
uniprot id: A0A1B1NAB1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1758689:SGUI RS13045
gene id: 1758689:SGUI_RS13045
uniprot id: A0A1B1NEW2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS00995
gene id: 1758689:SGUI_RS00995
uniprot id: A0A1B1N870
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1758689:SGUI RS06530
gene id: 1758689:SGUI_RS06530
uniprot id: A0A1B1NB82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1758689:SGUI RS13625
gene id: 1758689:SGUI_RS13625
uniprot id: A0A1B1NF52
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1758689:SGUI RS10525
gene id: 1758689:SGUI_RS10525
uniprot id: A0A1B1NDF3
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS06410
gene id: 1758689:SGUI_RS06410
uniprot id: A0A1B1NB45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1758689:SGUI RS00540
gene id: 1758689:SGUI_RS00540
uniprot id: A0A1B1N7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS09670
gene id: 1758689:SGUI_RS09670
uniprot id: A0A1B1NCZ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1758689:SGUI RS06105
gene id: 1758689:SGUI_RS06105
uniprot id: A0A1B1NB43
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1758689:SGUI RS05645
gene id: 1758689:SGUI_RS05645
uniprot id: A0A1B1NAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1758689:SGUI RS03220
gene id: 1758689:SGUI_RS03220
uniprot id: A0A1B1N9G9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1758689:SGUI RS16115
gene id: 1758689:SGUI_RS16115
uniprot id: A0A1B1NGK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1758689:SGUI RS16765
gene id: 1758689:SGUI_RS16765
uniprot id: A0A1B1NGX6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1758689:SGUI RS15035
gene id: 1758689:SGUI_RS15035
uniprot id: A0A1B1NG01
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1758689:SGUI RS04315
gene id: 1758689:SGUI_RS04315
uniprot id: A0A1B1N9Y1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1758689:SGUI RS05080
gene id: 1758689:SGUI_RS05080
uniprot id: A0A1B1NAC2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1758689:SGUI RS02535
gene id: 1758689:SGUI_RS02535
uniprot id: A0A1B1N8Y2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1758689:SGUI RS16840
gene id: 1758689:SGUI_RS16840
uniprot id: A0A1B1NGY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1758689:SGUI RS08375
gene id: 1758689:SGUI_RS08375
uniprot id: A0A1B1NC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1758689:SGUI RS06525
gene id: 1758689:SGUI_RS06525
uniprot id: A0A1B1NB75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1758689:SGUI RS03270
gene id: 1758689:SGUI_RS03270
uniprot id: A0A1B1N9I3
names: Similarity
messages: Belongs to the YciI family.

1758689:SGUI RS15775
gene id: 1758689:SGUI_RS15775
uniprot id: A0A1B1NGD8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1758689:SGUI RS07435
gene id: 1758689:SGUI_RS07435
uniprot id: A0A1B1NBP1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

1758689:SGUI RS00145
gene id: 1758689:SGUI_RS00145
uniprot id: A0A1B1N7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS11160
gene id: 1758689:SGUI_RS11160
uniprot id: A0A1B1NDR4
names: Similarity
messages: Belongs to the TPP enzyme family.

1758689:SGUI RS05965
gene id: 1758689:SGUI_RS05965
uniprot id: A0A1B1NB16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1758689:SGUI RS08380
gene id: 1758689:SGUI_RS08380
uniprot id: A0A1B1NC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1758689:SGUI RS15175
gene id: 1758689:SGUI_RS15175
uniprot id: A0A1B1NG28
names: Similarity
messages: Belongs to the group II decarboxylase family.

1758689:SGUI RS10995
gene id: 1758689:SGUI_RS10995
uniprot id: A0A1B1NDR2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1758689:SGUI RS14490
gene id: 1758689:SGUI_RS14490
uniprot id: A0A1B1NFN9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1758689:SGUI RS08235
gene id: 1758689:SGUI_RS08235
uniprot id: A0A1B1NC56
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1758689:SGUI RS05065
gene id: 1758689:SGUI_RS05065
uniprot id: A0A1B1NAD1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1758689:SGUI RS03655
gene id: 1758689:SGUI_RS03655
uniprot id: A0A1B1N9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1758689:SGUI RS12890
gene id: 1758689:SGUI_RS12890
uniprot id: A0A1B1NER9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1758689:SGUI RS12900
gene id: 1758689:SGUI_RS12900
uniprot id: A0A1B1NET8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1758689:SGUI RS12500
gene id: 1758689:SGUI_RS12500
uniprot id: A0A1B1NEH1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1758689:SGUI RS02175
gene id: 1758689:SGUI_RS02175
uniprot id: A0A1B1N8T3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1758689:SGUI RS13015
gene id: 1758689:SGUI_RS13015
uniprot id: A0A1B1NET0
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS08890
gene id: 1758689:SGUI_RS08890
uniprot id: A0A1B1NCM4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1758689:SGUI RS18065
gene id: 1758689:SGUI_RS18065
uniprot id: A0A1B1NDJ9
names: Similarity
messages: Belongs to the peptidase C40 family.

1758689:SGUI RS08570
gene id: 1758689:SGUI_RS08570
uniprot id: A0A1B1NCC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1758689:SGUI RS14325
gene id: 1758689:SGUI_RS14325
uniprot id: A0A1B1NFI1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1758689:SGUI RS08070
gene id: 1758689:SGUI_RS08070
uniprot id: A0A1B1NC33
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

1758689:SGUI RS01165
gene id: 1758689:SGUI_RS01165
uniprot id: A0A1B1N867
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1758689:SGUI RS06165
gene id: 1758689:SGUI_RS06165
uniprot id: A0A1B1NAZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS09185
gene id: 1758689:SGUI_RS09185
uniprot id: A0A1B1NCT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1758689:SGUI RS14825
gene id: 1758689:SGUI_RS14825
uniprot id: A0A1B1NFV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1758689:SGUI RS07420
gene id: 1758689:SGUI_RS07420
uniprot id: A0A1B1NBP8
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1758689:SGUI RS12555
gene id: 1758689:SGUI_RS12555
uniprot id: A0A1B1NEK9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1758689:SGUI RS09510
gene id: 1758689:SGUI_RS09510
uniprot id: A0A1B1ND25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1758689:SGUI RS00205
gene id: 1758689:SGUI_RS00205
uniprot id: A0A1B1N7N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1758689:SGUI RS07020
gene id: 1758689:SGUI_RS07020
uniprot id: A0A1B1NBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1758689:SGUI RS18195
gene id: 1758689:SGUI_RS18195
uniprot id: A0A1B1NDR5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1758689:SGUI RS13630
gene id: 1758689:SGUI_RS13630
uniprot id: A0A1B1NFC5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1758689:SGUI RS07740
gene id: 1758689:SGUI_RS07740
uniprot id: A0A1B1NBZ0
names: Similarity
messages: Belongs to the GARS family.

1758689:SGUI RS13110
gene id: 1758689:SGUI_RS13110
uniprot id: A0A1B1NEX3
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1758689:SGUI RS18255
gene id: 1758689:SGUI_RS18255
uniprot id: A0A1B1N8I3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS16580
gene id: 1758689:SGUI_RS16580
uniprot id: A0A1B1NGT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1758689:SGUI RS16900
gene id: 1758689:SGUI_RS16900
uniprot id: A0A1B1NH01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1758689:SGUI RS14865
gene id: 1758689:SGUI_RS14865
uniprot id: A0A1B1NFW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1758689:SGUI RS05625
gene id: 1758689:SGUI_RS05625
uniprot id: A0A1B1NAS4
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS00030
gene id: 1758689:SGUI_RS00030
uniprot id: A0A1B1N7K9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1758689:SGUI RS13355
gene id: 1758689:SGUI_RS13355
uniprot id: A0A1B1NF09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS00350
gene id: 1758689:SGUI_RS00350
uniprot id: A0A1B1N7V0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1758689:SGUI RS01355
gene id: 1758689:SGUI_RS01355
uniprot id: A0A1B1N8A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1758689:SGUI RS14365
gene id: 1758689:SGUI_RS14365
uniprot id: A0A1B1NFL7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1758689:SGUI RS12100
gene id: 1758689:SGUI_RS12100
uniprot id: A0A1B1NEC7
names: Similarity
messages: Belongs to the DapB family.

1758689:SGUI RS05925
gene id: 1758689:SGUI_RS05925
uniprot id: A0A1B1NAU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1758689:SGUI RS11865
gene id: 1758689:SGUI_RS11865
uniprot id: A0A1B1NE58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1758689:SGUI RS15835
gene id: 1758689:SGUI_RS15835
uniprot id: A0A1B1NGF0
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS15705
gene id: 1758689:SGUI_RS15705
uniprot id: A0A1B1NGC2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1758689:SGUI RS03105
gene id: 1758689:SGUI_RS03105
uniprot id: A0A1B1N996
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1758689:SGUI RS07035
gene id: 1758689:SGUI_RS07035
uniprot id: A0A1B1NBJ5
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS05340
gene id: 1758689:SGUI_RS05340
uniprot id: A0A1B1NAL7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1758689:SGUI RS04425
gene id: 1758689:SGUI_RS04425
uniprot id: A0A1B1N9Z7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1758689:SGUI RS07300
gene id: 1758689:SGUI_RS07300
uniprot id: A0A1B1NBM9
names: Cofactor
messages: Binds 1 FAD per subunit.

1758689:SGUI RS11700
gene id: 1758689:SGUI_RS11700
uniprot id: A0A1B1NE33
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1758689:SGUI RS05595
gene id: 1758689:SGUI_RS05595
uniprot id: A0A1B1NAP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1758689:SGUI RS02240
gene id: 1758689:SGUI_RS02240
uniprot id: A0A1B1N8S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1758689:SGUI RS06570
gene id: 1758689:SGUI_RS06570
uniprot id: A0A1B1NB84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1758689:SGUI RS03935
gene id: 1758689:SGUI_RS03935
uniprot id: A0A1B1N9N3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1758689:SGUI RS00980
gene id: 1758689:SGUI_RS00980
uniprot id: A0A1B1N824
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1758689:SGUI RS00535
gene id: 1758689:SGUI_RS00535
uniprot id: A0A1B1N7U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS01330
gene id: 1758689:SGUI_RS01330
uniprot id: A0A1B1N894
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1758689:SGUI RS02385
gene id: 1758689:SGUI_RS02385
uniprot id: A0A1B1N8X1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1758689:SGUI RS04585
gene id: 1758689:SGUI_RS04585
uniprot id: A0A1B1NA46
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1758689:SGUI RS14785
gene id: 1758689:SGUI_RS14785
uniprot id: A0A1B1NFU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1758689:SGUI RS10625
gene id: 1758689:SGUI_RS10625
uniprot id: A0A1B1NDJ0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1758689:SGUI RS07335
gene id: 1758689:SGUI_RS07335
uniprot id: A0A1B1NBM3
names: Similarity
messages: Belongs to the FemABX family.

1758689:SGUI RS15265
gene id: 1758689:SGUI_RS15265
uniprot id: A0A1B1NG11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1758689:SGUI RS01005
gene id: 1758689:SGUI_RS01005
uniprot id: A0A1B1N830
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1758689:SGUI RS15300
gene id: 1758689:SGUI_RS15300
uniprot id: A0A1B1NG51
names: Similarity
messages: Belongs to the LOG family.

1758689:SGUI RS07545
gene id: 1758689:SGUI_RS07545
uniprot id: A0A1B1NBT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1758689:SGUI RS11825
gene id: 1758689:SGUI_RS11825
uniprot id: A0A1B1NE46
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1758689:SGUI RS02085
gene id: 1758689:SGUI_RS02085
uniprot id: A0A1B1N8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1758689:SGUI RS15735
gene id: 1758689:SGUI_RS15735
uniprot id: A0A1B1NGD4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1758689:SGUI RS00730
gene id: 1758689:SGUI_RS00730
uniprot id: A0A1B1N7Z2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1758689:SGUI RS02650
gene id: 1758689:SGUI_RS02650
uniprot id: A0A1B1N925
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS09785
gene id: 1758689:SGUI_RS09785
uniprot id: A0A1B1ND05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS12665
gene id: 1758689:SGUI_RS12665
uniprot id: A0A1B1NEP1
names: Similarity
messages: Belongs to the CutA family.

1758689:SGUI RS05490
gene id: 1758689:SGUI_RS05490
uniprot id: A0A1B1NAL6
names: Similarity
messages: Belongs to the MreC family.

1758689:SGUI RS16235
gene id: 1758689:SGUI_RS16235
uniprot id: A0A1B1NGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1758689:SGUI RS16250
gene id: 1758689:SGUI_RS16250
uniprot id: A0A1B1NGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1758689:SGUI RS04845
gene id: 1758689:SGUI_RS04845
uniprot id: A0A1B1NAC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1758689:SGUI RS16815
gene id: 1758689:SGUI_RS16815
uniprot id: A0A1B1NGY6
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS16730
gene id: 1758689:SGUI_RS16730
uniprot id: A0A1B1NGV6
names: Cofactor
messages: Can also use Mn(2+) ion.

1758689:SGUI RS15470
gene id: 1758689:SGUI_RS15470
uniprot id: A0A1B1NG55
names: Similarity
messages: Belongs to the peptidase S16 family.

1758689:SGUI RS00860
gene id: 1758689:SGUI_RS00860
uniprot id: A0A1B1N801
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1758689:SGUI RS04225
gene id: 1758689:SGUI_RS04225
uniprot id: A0A1B1N9V6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS02585
gene id: 1758689:SGUI_RS02585
uniprot id: A0A1B1N942
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS15815
gene id: 1758689:SGUI_RS15815
uniprot id: A0A1B1NGE5
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1758689:SGUI RS15575
gene id: 1758689:SGUI_RS15575
uniprot id: A0A1B1NG93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1758689:SGUI RS09665
gene id: 1758689:SGUI_RS09665
uniprot id: A0A1B1ND52
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1758689:SGUI RS15940
gene id: 1758689:SGUI_RS15940
uniprot id: A0A1B1NGH8
names: Similarity
messages: Belongs to the peptidase S9C family.

1758689:SGUI RS05730
gene id: 1758689:SGUI_RS05730
uniprot id: A0A1B1NAR4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1758689:SGUI RS05450
gene id: 1758689:SGUI_RS05450
uniprot id: A0A1B1NAL9
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1758689:SGUI RS09155
gene id: 1758689:SGUI_RS09155
uniprot id: A0A1B1NCU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1758689:SGUI RS15215
gene id: 1758689:SGUI_RS15215
uniprot id: A0A1B1NG06
names: Similarity
messages: Belongs to the universal stress protein A family.

1758689:SGUI RS03250
gene id: 1758689:SGUI_RS03250
uniprot id: A0A1B1N9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS04895
gene id: 1758689:SGUI_RS04895
uniprot id: A0A1B1NA86
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1758689:SGUI RS03495
gene id: 1758689:SGUI_RS03495
uniprot id: A0A1B1N9H4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1758689:SGUI RS01290
gene id: 1758689:SGUI_RS01290
uniprot id: A0A1B1N898
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1758689:SGUI RS00585
gene id: 1758689:SGUI_RS00585
uniprot id: A0A1B1N7X0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1758689:SGUI RS01405
gene id: 1758689:SGUI_RS01405
uniprot id: A0A1B1N8A8
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS12750
gene id: 1758689:SGUI_RS12750
uniprot id: A0A1B1NER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1758689:SGUI RS12495
gene id: 1758689:SGUI_RS12495
uniprot id: A0A1B1NEI3
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1758689:SGUI RS04580
gene id: 1758689:SGUI_RS04580
uniprot id: A0A1B1NA96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

1758689:SGUI RS07465
gene id: 1758689:SGUI_RS07465
uniprot id: A0A1B1NBQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1758689:SGUI RS00300
gene id: 1758689:SGUI_RS00300
uniprot id: A0A1B1N7T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1758689:SGUI RS03680
gene id: 1758689:SGUI_RS03680
uniprot id: A0A1B1N9L4
names: Similarity
messages: Belongs to the TPP enzyme family.

1758689:SGUI RS11815
gene id: 1758689:SGUI_RS11815
uniprot id: A0A1B1NE48
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1758689:SGUI RS04235
gene id: 1758689:SGUI_RS04235
uniprot id: A0A1B1NA17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1758689:SGUI RS09015
gene id: 1758689:SGUI_RS09015
uniprot id: A0A1B1NCK9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1758689:SGUI RS07700
gene id: 1758689:SGUI_RS07700
uniprot id: A0A1B1NBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1758689:SGUI RS06565
gene id: 1758689:SGUI_RS06565
uniprot id: A0A1B1NB76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1758689:SGUI RS16790
gene id: 1758689:SGUI_RS16790
uniprot id: A0A1B1NGX4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1758689:SGUI RS15060
gene id: 1758689:SGUI_RS15060
uniprot id: A0A1B1NFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1758689:SGUI RS16155
gene id: 1758689:SGUI_RS16155
uniprot id: A0A1B1NGL9
names: Similarity
messages: Belongs to the GSP E family.

1758689:SGUI RS04030
gene id: 1758689:SGUI_RS04030
uniprot id: A0A1B1N9S2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1758689:SGUI RS18150
gene id: 1758689:SGUI_RS18150
uniprot id: A0A1B1NFS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1758689:SGUI RS12740
gene id: 1758689:SGUI_RS12740
uniprot id: A0A1B1NEQ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1758689:SGUI RS10210
gene id: 1758689:SGUI_RS10210
uniprot id: A0A1B1ND98
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1758689:SGUI RS03950
gene id: 1758689:SGUI_RS03950
uniprot id: A0A1B1N9V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1758689:SGUI RS16620
gene id: 1758689:SGUI_RS16620
uniprot id: A0A1B1NGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1758689:SGUI RS16630
gene id: 1758689:SGUI_RS16630
uniprot id: A0A1B1NGU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1758689:SGUI RS07005
gene id: 1758689:SGUI_RS07005
uniprot id: A0A1B1NBH6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1758689:SGUI RS17285
gene id: 1758689:SGUI_RS17285
uniprot id: A0A1B1N7Y1
names: Similarity
messages: Belongs to the HisA/HisF family.

1758689:SGUI RS12270
gene id: 1758689:SGUI_RS12270
uniprot id: A0A1B1NEF2
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS03980
gene id: 1758689:SGUI_RS03980
uniprot id: A0A1B1N9T4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1758689:SGUI RS14330
gene id: 1758689:SGUI_RS14330
uniprot id: A0A1B1NFP7
names: Similarity
messages: Belongs to the fructosamine kinase family.

1758689:SGUI RS15115
gene id: 1758689:SGUI_RS15115
uniprot id: A0A1B1NFZ8
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS02245
gene id: 1758689:SGUI_RS02245
uniprot id: A0A1B1N8U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1758689:SGUI RS10275
gene id: 1758689:SGUI_RS10275
uniprot id: A0A1B1ND96
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1758689:SGUI RS14935
gene id: 1758689:SGUI_RS14935
uniprot id: A0A1B1NFW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1758689:SGUI RS15675
gene id: 1758689:SGUI_RS15675
uniprot id: A0A1B1NGA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1758689:SGUI RS00180
gene id: 1758689:SGUI_RS00180
uniprot id: A0A1B1N7M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1758689:SGUI RS01230
gene id: 1758689:SGUI_RS01230
uniprot id: A0A1B1N886
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1758689:SGUI RS06805
gene id: 1758689:SGUI_RS06805
uniprot id: A0A1B1NBC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1758689:SGUI RS06765
gene id: 1758689:SGUI_RS06765
uniprot id: A0A1B1NBB6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1758689:SGUI RS06515
gene id: 1758689:SGUI_RS06515
uniprot id: A0A1B1NB66
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1758689:SGUI RS15360
gene id: 1758689:SGUI_RS15360
uniprot id: A0A1B1NG71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1758689:SGUI RS15910
gene id: 1758689:SGUI_RS15910
uniprot id: A0A1B1NGG6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1758689:SGUI RS06020
gene id: 1758689:SGUI_RS06020
uniprot id: A0A1B1NAW6
names: Subcellular Location Annotation
messages: Membrane

1758689:SGUI RS03190
gene id: 1758689:SGUI_RS03190
uniprot id: A0A1B1N9B7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1758689:SGUI RS15830
gene id: 1758689:SGUI_RS15830
uniprot id: A0A1B1NGE8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1758689:SGUI RS14035
gene id: 1758689:SGUI_RS14035
uniprot id: A0A1B1NFC8
names: Similarity
messages: Belongs to the UPF0045 family.

1758689:SGUI RS14730
gene id: 1758689:SGUI_RS14730
uniprot id: A0A1B1NFT6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1758689:SGUI RS13225
gene id: 1758689:SGUI_RS13225
uniprot id: A0A1B1NEX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane