1743168:A8O14 RS02560
gene id: 1743168:A8O14_RS02560
uniprot id: A0A191UDE4
names: Similarity
messages: Belongs to the RecJ family.

1743168:A8O14 RS11060
gene id: 1743168:A8O14_RS11060
uniprot id: A0A191UI35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1743168:A8O14 RS05395
gene id: 1743168:A8O14_RS05395
uniprot id: A0A191UEW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1743168:A8O14 RS09680
gene id: 1743168:A8O14_RS09680
uniprot id: A0A191UH33
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS05365
gene id: 1743168:A8O14_RS05365
uniprot id: A0A191UF82
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1743168:A8O14 RS09690
gene id: 1743168:A8O14_RS09690
uniprot id: A0A191UHE4
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS00320
gene id: 1743168:A8O14_RS00320
uniprot id: A0A191UCI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1743168:A8O14 RS06240
gene id: 1743168:A8O14_RS06240
uniprot id: A0A191UFA1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1743168:A8O14 RS09805
gene id: 1743168:A8O14_RS09805
uniprot id: A0A191UHG5
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1743168:A8O14 RS02805
gene id: 1743168:A8O14_RS02805
uniprot id: A0A191UDZ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1743168:A8O14 RS02250
gene id: 1743168:A8O14_RS02250
uniprot id: A0A191UD92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1743168:A8O14 RS09820
gene id: 1743168:A8O14_RS09820
uniprot id: A0A191UH56
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1743168:A8O14 RS07185
gene id: 1743168:A8O14_RS07185
uniprot id: A0A191UFS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1743168:A8O14 RS00620
gene id: 1743168:A8O14_RS00620
uniprot id: A0A191UCX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1743168:A8O14 RS11260
gene id: 1743168:A8O14_RS11260
uniprot id: A0A191UI73
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1743168:A8O14 RS03045
gene id: 1743168:A8O14_RS03045
uniprot id: A0A191UE45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1743168:A8O14 RS04790
gene id: 1743168:A8O14_RS04790
uniprot id: A0A191UEZ0
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS11070
gene id: 1743168:A8O14_RS11070
uniprot id: A0A191UHU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1743168:A8O14 RS09115
gene id: 1743168:A8O14_RS09115
uniprot id: A0A191UGT2
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1743168:A8O14 RS06265
gene id: 1743168:A8O14_RS06265
uniprot id: A0A191UFA6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1743168:A8O14 RS09665
gene id: 1743168:A8O14_RS09665
uniprot id: A0A191UH64
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1743168:A8O14 RS11185
gene id: 1743168:A8O14_RS11185
uniprot id: A0A191UHV8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1743168:A8O14 RS00925
gene id: 1743168:A8O14_RS00925
uniprot id: A0A191UCU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1743168:A8O14 RS08265
gene id: 1743168:A8O14_RS08265
uniprot id: A0A191UGH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

1743168:A8O14 RS00285
gene id: 1743168:A8O14_RS00285
uniprot id: A0A191UCQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1743168:A8O14 RS00310
gene id: 1743168:A8O14_RS00310
uniprot id: A0A191UCQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1743168:A8O14 RS09715
gene id: 1743168:A8O14_RS09715
uniprot id: A0A191UHG3
names: Subcellular Location Annotation
messages: Cytoplasm

1743168:A8O14 RS00510
gene id: 1743168:A8O14_RS00510
uniprot id: A0A191UCT6
names: Similarity
messages: Belongs to the glutamate synthase family.

1743168:A8O14 RS07375
gene id: 1743168:A8O14_RS07375
uniprot id: A0A191UG22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1743168:A8O14 RS01180
gene id: 1743168:A8O14_RS01180
uniprot id: A0A191UCT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1743168:A8O14 RS04560
gene id: 1743168:A8O14_RS04560
uniprot id: A0A191UEI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1743168:A8O14 RS11120
gene id: 1743168:A8O14_RS11120
uniprot id: A0A191UHV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1743168:A8O14 RS03920
gene id: 1743168:A8O14_RS03920
uniprot id: A0A191UI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1743168:A8O14 RS11395
gene id: 1743168:A8O14_RS11395
uniprot id: A0A191UHY3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1743168:A8O14 RS01835
gene id: 1743168:A8O14_RS01835
uniprot id: A0A191UDH5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1743168:A8O14 RS11225
gene id: 1743168:A8O14_RS11225
uniprot id: A0A191UHW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1743168:A8O14 RS06430
gene id: 1743168:A8O14_RS06430
uniprot id: A0A191UFE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1743168:A8O14 RS09650
gene id: 1743168:A8O14_RS09650
uniprot id: A0A191UH28
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS09000
gene id: 1743168:A8O14_RS09000
uniprot id: A0A191UIQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1743168:A8O14 RS00425
gene id: 1743168:A8O14_RS00425
uniprot id: A0A191UCD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1743168:A8O14 RS03975
gene id: 1743168:A8O14_RS03975
uniprot id: A0A191UE33
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1743168:A8O14 RS08805
gene id: 1743168:A8O14_RS08805
uniprot id: A0A191UGR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1743168:A8O14 RS05905
gene id: 1743168:A8O14_RS05905
uniprot id: A0A191UFH4
names: Similarity
messages: Belongs to the peptidase C59 family.

1743168:A8O14 RS01665
gene id: 1743168:A8O14_RS01665
uniprot id: A0A191UCZ0
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS08405
gene id: 1743168:A8O14_RS08405
uniprot id: A0A191UGK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1743168:A8O14 RS00470
gene id: 1743168:A8O14_RS00470
uniprot id: A0A191UCT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1743168:A8O14 RS03950
gene id: 1743168:A8O14_RS03950
uniprot id: A0A191UE79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1743168:A8O14 RS05860
gene id: 1743168:A8O14_RS05860
uniprot id: A0A191UFG6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

1743168:A8O14 RS09745
gene id: 1743168:A8O14_RS09745
uniprot id: A0A191UHF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1743168:A8O14 RS00360
gene id: 1743168:A8O14_RS00360
uniprot id: A0A191UCR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1743168:A8O14 RS10695
gene id: 1743168:A8O14_RS10695
uniprot id: A0A191UHP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1743168:A8O14 RS06850
gene id: 1743168:A8O14_RS06850
uniprot id: A0A191UFT6
names: Similarity
messages: Belongs to the UxaA family.

1743168:A8O14 RS05600
gene id: 1743168:A8O14_RS05600
uniprot id: A0A191UEZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS10685
gene id: 1743168:A8O14_RS10685
uniprot id: A0A191UHY5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1743168:A8O14 RS10550
gene id: 1743168:A8O14_RS10550
uniprot id: A0A191UHI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS00730
gene id: 1743168:A8O14_RS00730
uniprot id: A0A191UCR3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1743168:A8O14 RS03715
gene id: 1743168:A8O14_RS03715
uniprot id: A0A191UEB2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1743168:A8O14 RS01190
gene id: 1743168:A8O14_RS01190
uniprot id: A0A191UD69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1743168:A8O14 RS03210
gene id: 1743168:A8O14_RS03210
uniprot id: A0A191UE14
names: Similarity
messages: Belongs to the leucine-binding protein family.

1743168:A8O14 RS09670
gene id: 1743168:A8O14_RS09670
uniprot id: A0A191UIR0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1743168:A8O14 RS07355
gene id: 1743168:A8O14_RS07355
uniprot id: A0A191UFV5
names: Similarity
messages: Belongs to the GARS family.

1743168:A8O14 RS00350
gene id: 1743168:A8O14_RS00350
uniprot id: A0A191UCB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1743168:A8O14 RS03935
gene id: 1743168:A8O14_RS03935
uniprot id: A0A191UEJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1743168:A8O14 RS03480
gene id: 1743168:A8O14_RS03480
uniprot id: A0A191UE09
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1743168:A8O14 RS02365
gene id: 1743168:A8O14_RS02365
uniprot id: A0A191UDK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1743168:A8O14 RS08510
gene id: 1743168:A8O14_RS08510
uniprot id: A0A191UGR9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1743168:A8O14 RS04695
gene id: 1743168:A8O14_RS04695
uniprot id: A0A191UEH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1743168:A8O14 RS08580
gene id: 1743168:A8O14_RS08580
uniprot id: A0A191UGJ8
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1743168:A8O14 RS03095
gene id: 1743168:A8O14_RS03095
uniprot id: A0A191UE52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1743168:A8O14 RS00560
gene id: 1743168:A8O14_RS00560
uniprot id: A0A191UCU6
names: Similarity
messages: Belongs to the BolA/IbaG family.

1743168:A8O14 RS09825
gene id: 1743168:A8O14_RS09825
uniprot id: A0A191UHI4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1743168:A8O14 RS05405
gene id: 1743168:A8O14_RS05405
uniprot id: A0A191UF86
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1743168:A8O14 RS00900
gene id: 1743168:A8O14_RS00900
uniprot id: A0A191UCU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS06880
gene id: 1743168:A8O14_RS06880
uniprot id: A0A191UFM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

1743168:A8O14 RS01490
gene id: 1743168:A8O14_RS01490
uniprot id: A0A191UD46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS00335
gene id: 1743168:A8O14_RS00335
uniprot id: A0A191UCQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1743168:A8O14 RS09320
gene id: 1743168:A8O14_RS09320
uniprot id: A0A191UGX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1743168:A8O14 RS02170
gene id: 1743168:A8O14_RS02170
uniprot id: A0A191UDH6
names: Similarity
messages: Belongs to the PhoH family.

1743168:A8O14 RS05695
gene id: 1743168:A8O14_RS05695
uniprot id: A0A191UFD6
names: Similarity
messages: Belongs to the aspartokinase family.

1743168:A8O14 RS05300
gene id: 1743168:A8O14_RS05300
uniprot id: A0A191UF74
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1743168:A8O14 RS01185
gene id: 1743168:A8O14_RS01185
uniprot id: A0A191UD58
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1743168:A8O14 RS09760
gene id: 1743168:A8O14_RS09760
uniprot id: A0A191UH47
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1743168:A8O14 RS00325
gene id: 1743168:A8O14_RS00325
uniprot id: A0A191UCB3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1743168:A8O14 RS02550
gene id: 1743168:A8O14_RS02550
uniprot id: A0A191UDP1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS08785
gene id: 1743168:A8O14_RS08785
uniprot id: A0A191UGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1743168:A8O14 RS09075
gene id: 1743168:A8O14_RS09075
uniprot id: A0A191UH44
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1743168:A8O14 RS00570
gene id: 1743168:A8O14_RS00570
uniprot id: A0A191UCN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1743168:A8O14 RS08585
gene id: 1743168:A8O14_RS08585
uniprot id: A0A191UGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1743168:A8O14 RS09105
gene id: 1743168:A8O14_RS09105
uniprot id: A0A191UH40
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1743168:A8O14 RS11335
gene id: 1743168:A8O14_RS11335
uniprot id: A0A191UHX9
names: Similarity
messages: Belongs to the MipA/OmpV family.

1743168:A8O14 RS09495
gene id: 1743168:A8O14_RS09495
uniprot id: A0A191UHA7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1743168:A8O14 RS01850
gene id: 1743168:A8O14_RS01850
uniprot id: A0A191UD51
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1743168:A8O14 RS01230
gene id: 1743168:A8O14_RS01230
uniprot id: A0A191UCU7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1743168:A8O14 RS10885
gene id: 1743168:A8O14_RS10885
uniprot id: A0A191UI18
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1743168:A8O14 RS08965
gene id: 1743168:A8O14_RS08965
uniprot id: A0A191UH22
names: Similarity
messages: Belongs to the histone deacetylase family.

1743168:A8O14 RS07990
gene id: 1743168:A8O14_RS07990
uniprot id: A0A191UGD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1743168:A8O14 RS00115
gene id: 1743168:A8O14_RS00115
uniprot id: A0A191UCM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1743168:A8O14 RS06905
gene id: 1743168:A8O14_RS06905
uniprot id: A0A191UFM7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1743168:A8O14 RS08415
gene id: 1743168:A8O14_RS08415
uniprot id: A0A191UGF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
messages: Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB.

1743168:A8O14 RS11055
gene id: 1743168:A8O14_RS11055
uniprot id: A0A191UIR9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1743168:A8O14 RS09685
gene id: 1743168:A8O14_RS09685
uniprot id: A0A191UHF8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1743168:A8O14 RS00395
gene id: 1743168:A8O14_RS00395
uniprot id: A0A191UCK0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1743168:A8O14 RS03305
gene id: 1743168:A8O14_RS03305
uniprot id: A0A191UE90
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1743168:A8O14 RS01975
gene id: 1743168:A8O14_RS01975
uniprot id: A0A191UDK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1743168:A8O14 RS07150
gene id: 1743168:A8O14_RS07150
uniprot id: A0A191UFR9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1743168:A8O14 RS00275
gene id: 1743168:A8O14_RS00275
uniprot id: A0A191UCC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1743168:A8O14 RS00670
gene id: 1743168:A8O14_RS00670
uniprot id: A0A191UCY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1743168:A8O14 RS08575
gene id: 1743168:A8O14_RS08575
uniprot id: A0A191UGJ3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1743168:A8O14 RS10855
gene id: 1743168:A8O14_RS10855
uniprot id: A0A191UHQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1743168:A8O14 RS06450
gene id: 1743168:A8O14_RS06450
uniprot id: A0A191UFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1743168:A8O14 RS10745
gene id: 1743168:A8O14_RS10745
uniprot id: A0A191UHX6
names: Similarity
messages: Belongs to the peptidase M16 family.

1743168:A8O14 RS09810
gene id: 1743168:A8O14_RS09810
uniprot id: A0A191UH86
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1743168:A8O14 RS00050
gene id: 1743168:A8O14_RS00050
uniprot id: A0A191UCE6
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS07655
gene id: 1743168:A8O14_RS07655
uniprot id: A0A191UG13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1743168:A8O14 RS10895
gene id: 1743168:A8O14_RS10895
uniprot id: A0A191UHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS09975
gene id: 1743168:A8O14_RS09975
uniprot id: A0A191UH79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1743168:A8O14 RS01945
gene id: 1743168:A8O14_RS01945
uniprot id: A0A191UI40
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1743168:A8O14 RS08485
gene id: 1743168:A8O14_RS08485
uniprot id: A0A191UIG3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1743168:A8O14 RS01865
gene id: 1743168:A8O14_RS01865
uniprot id: A0A191UDI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1743168:A8O14 RS00590
gene id: 1743168:A8O14_RS00590
uniprot id: A0A191UCV1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1743168:A8O14 RS01755
gene id: 1743168:A8O14_RS01755
uniprot id: A0A191UD37
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1743168:A8O14 RS10620
gene id: 1743168:A8O14_RS10620
uniprot id: A0A191UHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS10470
gene id: 1743168:A8O14_RS10470
uniprot id: A0A191UHU0
names: Similarity
messages: Belongs to the peptidase M24B family.

1743168:A8O14 RS06660
gene id: 1743168:A8O14_RS06660
uniprot id: A0A191UFI3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1743168:A8O14 RS02405
gene id: 1743168:A8O14_RS02405
uniprot id: A0A191UDS7
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1743168:A8O14 RS06000
gene id: 1743168:A8O14_RS06000
uniprot id: A0A191UF61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1743168:A8O14 RS08165
gene id: 1743168:A8O14_RS08165
uniprot id: A0A191UIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS05820
gene id: 1743168:A8O14_RS05820
uniprot id: A0A191UF17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1743168:A8O14 RS01200
gene id: 1743168:A8O14_RS01200
uniprot id: A0A191UCR5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1743168:A8O14 RS04845
gene id: 1743168:A8O14_RS04845
uniprot id: A0A191UF16
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1743168:A8O14 RS09765
gene id: 1743168:A8O14_RS09765
uniprot id: A0A191UH46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1743168:A8O14 RS09490
gene id: 1743168:A8O14_RS09490
uniprot id: A0A191UHC0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS04255
gene id: 1743168:A8O14_RS04255
uniprot id: A0A191UEQ1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1743168:A8O14 RS07070
gene id: 1743168:A8O14_RS07070
uniprot id: A0A191UG10
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS03200
gene id: 1743168:A8O14_RS03200
uniprot id: A0A191UE71
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS05755
gene id: 1743168:A8O14_RS05755
uniprot id: A0A191UFB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1743168:A8O14 RS04565
gene id: 1743168:A8O14_RS04565
uniprot id: A0A191UEV0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1743168:A8O14 RS10650
gene id: 1743168:A8O14_RS10650
uniprot id: A0A191UHL2
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1743168:A8O14 RS01215
gene id: 1743168:A8O14_RS01215
uniprot id: A0A191UD74
names: Similarity
messages: Belongs to the barstar family.

1743168:A8O14 RS04400
gene id: 1743168:A8O14_RS04400
uniprot id: A0A191UEM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1743168:A8O14 RS10015
gene id: 1743168:A8O14_RS10015
uniprot id: A0A191UHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1743168:A8O14 RS05580
gene id: 1743168:A8O14_RS05580
uniprot id: A0A191UFB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1743168:A8O14 RS05735
gene id: 1743168:A8O14_RS05735
uniprot id: A0A191UIB1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1743168:A8O14 RS10170
gene id: 1743168:A8O14_RS10170
uniprot id: A0A191UHL6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1743168:A8O14 RS10810
gene id: 1743168:A8O14_RS10810
uniprot id: A0A191UHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1743168:A8O14 RS01990
gene id: 1743168:A8O14_RS01990
uniprot id: A0A191UD78
names: Similarity
messages: Belongs to the peptidase S49 family.

1743168:A8O14 RS09705
gene id: 1743168:A8O14_RS09705
uniprot id: A0A191UH30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1743168:A8O14 RS07380
gene id: 1743168:A8O14_RS07380
uniprot id: A0A191UFV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1743168:A8O14 RS09560
gene id: 1743168:A8O14_RS09560
uniprot id: A0A191UII9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1743168:A8O14 RS07310
gene id: 1743168:A8O14_RS07310
uniprot id: A0A191UG55
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1743168:A8O14 RS07095
gene id: 1743168:A8O14_RS07095
uniprot id: A0A191UFQ7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1743168:A8O14 RS09775
gene id: 1743168:A8O14_RS09775
uniprot id: A0A191UIJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS10370
gene id: 1743168:A8O14_RS10370
uniprot id: A0A191UHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1743168:A8O14 RS01525
gene id: 1743168:A8O14_RS01525
uniprot id: A0A191UCZ7
names: Similarity
messages: Belongs to the UPF0434 family.

1743168:A8O14 RS10610
gene id: 1743168:A8O14_RS10610
uniprot id: A0A191UHU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1743168:A8O14 RS04725
gene id: 1743168:A8O14_RS04725
uniprot id: A0A191UEL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1743168:A8O14 RS02810
gene id: 1743168:A8O14_RS02810
uniprot id: A0A191UDZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1743168:A8O14 RS10350
gene id: 1743168:A8O14_RS10350
uniprot id: A0A191UHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1743168:A8O14 RS00750
gene id: 1743168:A8O14_RS00750
uniprot id: A0A191UCZ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1743168:A8O14 RS08270
gene id: 1743168:A8O14_RS08270
uniprot id: A0A191UGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1743168:A8O14 RS07290
gene id: 1743168:A8O14_RS07290
uniprot id: A0A191UG06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1743168:A8O14 RS05660
gene id: 1743168:A8O14_RS05660
uniprot id: A0A191UFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS02410
gene id: 1743168:A8O14_RS02410
uniprot id: A0A191UDT3
names: Similarity
messages: Belongs to the class-I fumarase family.

1743168:A8O14 RS01255
gene id: 1743168:A8O14_RS01255
uniprot id: A0A191UD03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1743168:A8O14 RS08705
gene id: 1743168:A8O14_RS08705
uniprot id: A0A191UGL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1743168:A8O14 RS07780
gene id: 1743168:A8O14_RS07780
uniprot id: A0A191UG91
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1743168:A8O14 RS05170
gene id: 1743168:A8O14_RS05170
uniprot id: A0A191UF54
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1743168:A8O14 RS07720
gene id: 1743168:A8O14_RS07720
uniprot id: A0A191UGC6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1743168:A8O14 RS08330
gene id: 1743168:A8O14_RS08330
uniprot id: A0A191UGD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

1743168:A8O14 RS08110
gene id: 1743168:A8O14_RS08110
uniprot id: A0A191UGK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1743168:A8O14 RS10980
gene id: 1743168:A8O14_RS10980
uniprot id: A0A191UHS3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1743168:A8O14 RS04520
gene id: 1743168:A8O14_RS04520
uniprot id: A0A191UEE1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1743168:A8O14 RS08335
gene id: 1743168:A8O14_RS08335
uniprot id: A0A191UGQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS04800
gene id: 1743168:A8O14_RS04800
uniprot id: A0A191UEV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1743168:A8O14 RS11465
gene id: 1743168:A8O14_RS11465
uniprot id: A0A191UIN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS07325
gene id: 1743168:A8O14_RS07325
uniprot id: A0A191UFV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1743168:A8O14 RS07250
gene id: 1743168:A8O14_RS07250
uniprot id: A0A191UG39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS10515
gene id: 1743168:A8O14_RS10515
uniprot id: A0A191UIQ7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1743168:A8O14 RS10835
gene id: 1743168:A8O14_RS10835
uniprot id: A0A191UI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1743168:A8O14 RS01365
gene id: 1743168:A8O14_RS01365
uniprot id: A0A191UD25
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1743168:A8O14 RS03820
gene id: 1743168:A8O14_RS03820
uniprot id: A0A191UE62
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1743168:A8O14 RS10045
gene id: 1743168:A8O14_RS10045
uniprot id: A0A191UH91
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1743168:A8O14 RS08290
gene id: 1743168:A8O14_RS08290
uniprot id: A0A191UGI1
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

1743168:A8O14 RS09985
gene id: 1743168:A8O14_RS09985
uniprot id: A0A191UHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1743168:A8O14 RS06810
gene id: 1743168:A8O14_RS06810
uniprot id: A0A191UID2
names: Similarity
messages: Belongs to the pirin family.

1743168:A8O14 RS04770
gene id: 1743168:A8O14_RS04770
uniprot id: A0A191UEU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1743168:A8O14 RS00445
gene id: 1743168:A8O14_RS00445
uniprot id: A0A191UCL2
names: Similarity
messages: Belongs to the CutA family.

1743168:A8O14 RS00390
gene id: 1743168:A8O14_RS00390
uniprot id: A0A191UCS9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1743168:A8O14 RS04740
gene id: 1743168:A8O14_RS04740
uniprot id: A0A191UEZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1743168:A8O14 RS05840
gene id: 1743168:A8O14_RS05840
uniprot id: A0A191UFC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS08875
gene id: 1743168:A8O14_RS08875
uniprot id: A0A191UGQ3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1743168:A8O14 RS03705
gene id: 1743168:A8O14_RS03705
uniprot id: A0A191UEF6
names: Similarity
messages: Belongs to the DapA family.

1743168:A8O14 RS09615
gene id: 1743168:A8O14_RS09615
uniprot id: A0A191UH12
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS08765
gene id: 1743168:A8O14_RS08765
uniprot id: A0A191UGN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1743168:A8O14 RS06750
gene id: 1743168:A8O14_RS06750
uniprot id: A0A191UFW3
names: Similarity
messages: Belongs to the PrpD family.

1743168:A8O14 RS05150
gene id: 1743168:A8O14_RS05150
uniprot id: A0A191UF62
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS00410
gene id: 1743168:A8O14_RS00410
uniprot id: A0A191UCS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1743168:A8O14 RS02795
gene id: 1743168:A8O14_RS02795
uniprot id: A0A191UDI2
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1743168:A8O14 RS01060
gene id: 1743168:A8O14_RS01060
uniprot id: A0A191UCP0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1743168:A8O14 RS04285
gene id: 1743168:A8O14_RS04285
uniprot id: A0A191UEQ4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1743168:A8O14 RS11090
gene id: 1743168:A8O14_RS11090
uniprot id: A0A191UHV1
names: Subcellular Location Annotation
messages: Mitochondrion

1743168:A8O14 RS04605
gene id: 1743168:A8O14_RS04605
uniprot id: A0A191UES0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1743168:A8O14 RS02765
gene id: 1743168:A8O14_RS02765
uniprot id: A0A191UDS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1743168:A8O14 RS00295
gene id: 1743168:A8O14_RS00295
uniprot id: A0A191UCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1743168:A8O14 RS10480
gene id: 1743168:A8O14_RS10480
uniprot id: A0A191UHK1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1743168:A8O14 RS00060
gene id: 1743168:A8O14_RS00060
uniprot id: A0A191UCA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1743168:A8O14 RS08890
gene id: 1743168:A8O14_RS08890
uniprot id: A0A191UGS5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1743168:A8O14 RS07955
gene id: 1743168:A8O14_RS07955
uniprot id: A0A191UGH4
names: Similarity
messages: Belongs to the pirin family.

1743168:A8O14 RS04685
gene id: 1743168:A8O14_RS04685
uniprot id: A0A191UEY8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1743168:A8O14 RS03885
gene id: 1743168:A8O14_RS03885
uniprot id: A0A191UE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1743168:A8O14 RS05295
gene id: 1743168:A8O14_RS05295
uniprot id: A0A191UEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1743168:A8O14 RS11110
gene id: 1743168:A8O14_RS11110
uniprot id: A0A191UI43
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1743168:A8O14 RS04005
gene id: 1743168:A8O14_RS04005
uniprot id: A0A191UE91
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS07710
gene id: 1743168:A8O14_RS07710
uniprot id: A0A191UG18
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1743168:A8O14 RS01600
gene id: 1743168:A8O14_RS01600
uniprot id: A0A191UD68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

1743168:A8O14 RS09710
gene id: 1743168:A8O14_RS09710
uniprot id: A0A191UH35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1743168:A8O14 RS07145
gene id: 1743168:A8O14_RS07145
uniprot id: A0A191UFY2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1743168:A8O14 RS09945
gene id: 1743168:A8O14_RS09945
uniprot id: A0A191UHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1743168:A8O14 RS03025
gene id: 1743168:A8O14_RS03025
uniprot id: A0A191UDX7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1743168:A8O14 RS03850
gene id: 1743168:A8O14_RS03850
uniprot id: A0A191UE15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1743168:A8O14 RS04305
gene id: 1743168:A8O14_RS04305
uniprot id: A0A191UEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS02080
gene id: 1743168:A8O14_RS02080
uniprot id: A0A191UDG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1743168:A8O14 RS05420
gene id: 1743168:A8O14_RS05420
uniprot id: A0A191UEU6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1743168:A8O14 RS09375
gene id: 1743168:A8O14_RS09375
uniprot id: A0A191UH85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1743168:A8O14 RS11095
gene id: 1743168:A8O14_RS11095
uniprot id: A0A191UHU6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1743168:A8O14 RS04550
gene id: 1743168:A8O14_RS04550
uniprot id: A0A191UEQ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1743168:A8O14 RS08235
gene id: 1743168:A8O14_RS08235
uniprot id: A0A191UGH0
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1743168:A8O14 RS10795
gene id: 1743168:A8O14_RS10795
uniprot id: A0A191UHN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS03745
gene id: 1743168:A8O14_RS03745
uniprot id: A0A191UE00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS01105
gene id: 1743168:A8O14_RS01105
uniprot id: A0A191UD55
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1743168:A8O14 RS10925
gene id: 1743168:A8O14_RS10925
uniprot id: A0A191UHS0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1743168:A8O14 RS10400
gene id: 1743168:A8O14_RS10400
uniprot id: A0A191UHF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1743168:A8O14 RS04940
gene id: 1743168:A8O14_RS04940
uniprot id: A0A191UF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS03760
gene id: 1743168:A8O14_RS03760
uniprot id: A0A191UEG6
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS00960
gene id: 1743168:A8O14_RS00960
uniprot id: A0A191UCP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1743168:A8O14 RS05810
gene id: 1743168:A8O14_RS05810
uniprot id: A0A191UFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1743168:A8O14 RS10705
gene id: 1743168:A8O14_RS10705
uniprot id: A0A191UHM1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1743168:A8O14 RS07120
gene id: 1743168:A8O14_RS07120
uniprot id: A0A191UFR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1743168:A8O14 RS10760
gene id: 1743168:A8O14_RS10760
uniprot id: A0A191UHN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1743168:A8O14 RS11000
gene id: 1743168:A8O14_RS11000
uniprot id: A0A191UI24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1743168:A8O14 RS08725
gene id: 1743168:A8O14_RS08725
uniprot id: A0A191UGQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1743168:A8O14 RS01110
gene id: 1743168:A8O14_RS01110
uniprot id: A0A191UCX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1743168:A8O14 RS05570
gene id: 1743168:A8O14_RS05570
uniprot id: A0A191UEZ1
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1743168:A8O14 RS04675
gene id: 1743168:A8O14_RS04675
uniprot id: A0A191UEK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1743168:A8O14 RS01965
gene id: 1743168:A8O14_RS01965
uniprot id: A0A191UD72
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1743168:A8O14 RS01530
gene id: 1743168:A8O14_RS01530
uniprot id: A0A191UDB5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1743168:A8O14 RS10255
gene id: 1743168:A8O14_RS10255
uniprot id: A0A191UHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1743168:A8O14 RS03525
gene id: 1743168:A8O14_RS03525
uniprot id: A0A191UED1
names: Similarity
messages: Belongs to the FeoA family.

1743168:A8O14 RS04215
gene id: 1743168:A8O14_RS04215
uniprot id: A0A191UEJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1743168:A8O14 RS06685
gene id: 1743168:A8O14_RS06685
uniprot id: A0A191UFI7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1743168:A8O14 RS03265
gene id: 1743168:A8O14_RS03265
uniprot id: A0A191UE26
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1743168:A8O14 RS11065
gene id: 1743168:A8O14_RS11065
uniprot id: A0A191UHU2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS02125
gene id: 1743168:A8O14_RS02125
uniprot id: A0A191UI49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1743168:A8O14 RS02475
gene id: 1743168:A8O14_RS02475
uniprot id: A0A191UDD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1743168:A8O14 RS05145
gene id: 1743168:A8O14_RS05145
uniprot id: A0A191UF52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1743168:A8O14 RS00800
gene id: 1743168:A8O14_RS00800
uniprot id: A0A191UCY8
names: Similarity
messages: Belongs to the TrpC family.

1743168:A8O14 RS04110
gene id: 1743168:A8O14_RS04110
uniprot id: A0A191UEH6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1743168:A8O14 RS01010
gene id: 1743168:A8O14_RS01010
uniprot id: A0A191UCQ7
names: Similarity
messages: Belongs to the GSP E family.

1743168:A8O14 RS02775
gene id: 1743168:A8O14_RS02775
uniprot id: A0A191UDL6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS04890
gene id: 1743168:A8O14_RS04890
uniprot id: A0A191UF20
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS05795
gene id: 1743168:A8O14_RS05795
uniprot id: A0A191UF13
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1743168:A8O14 RS01470
gene id: 1743168:A8O14_RS01470
uniprot id: A0A191UCV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1743168:A8O14 RS07975
gene id: 1743168:A8O14_RS07975
uniprot id: A0A191UG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS10770
gene id: 1743168:A8O14_RS10770
uniprot id: A0A191UHY6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1743168:A8O14 RS05160
gene id: 1743168:A8O14_RS05160
uniprot id: A0A191UEQ6
names: Similarity
messages: Belongs to the BolA/IbaG family.

1743168:A8O14 RS03355
gene id: 1743168:A8O14_RS03355
uniprot id: A0A191UDY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1743168:A8O14 RS10095
gene id: 1743168:A8O14_RS10095
uniprot id: A0A191UH99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1743168:A8O14 RS02380
gene id: 1743168:A8O14_RS02380
uniprot id: A0A191UDS2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1743168:A8O14 RS07665
gene id: 1743168:A8O14_RS07665
uniprot id: A0A191UGC2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1743168:A8O14 RS00665
gene id: 1743168:A8O14_RS00665
uniprot id: A0A191UCW8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1743168:A8O14 RS07390
gene id: 1743168:A8O14_RS07390
uniprot id: A0A191UG68
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS08835
gene id: 1743168:A8O14_RS08835
uniprot id: A0A191UGN4
names: Similarity
messages: Belongs to the nitroreductase family.

1743168:A8O14 RS04315
gene id: 1743168:A8O14_RS04315
uniprot id: A0A191UER6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1743168:A8O14 RS00605
gene id: 1743168:A8O14_RS00605
uniprot id: A0A191UCG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS05130
gene id: 1743168:A8O14_RS05130
uniprot id: A0A191UF11
names: Similarity
messages: Belongs to the WrbA family.

1743168:A8O14 RS05260
gene id: 1743168:A8O14_RS05260
uniprot id: A0A191UF69
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS05310
gene id: 1743168:A8O14_RS05310
uniprot id: A0A191UF38
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS03505
gene id: 1743168:A8O14_RS03505
uniprot id: A0A191UDW2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1743168:A8O14 RS02035
gene id: 1743168:A8O14_RS02035
uniprot id: A0A191UD54
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1743168:A8O14 RS05325
gene id: 1743168:A8O14_RS05325
uniprot id: A0A191UEV9
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1743168:A8O14 RS10875
gene id: 1743168:A8O14_RS10875
uniprot id: A0A191UHP6
names: Subcellular Location Annotation
messages: Cytoplasm

1743168:A8O14 RS09835
gene id: 1743168:A8O14_RS09835
uniprot id: A0A191UH92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1743168:A8O14 RS00240
gene id: 1743168:A8O14_RS00240
uniprot id: A0A191UCH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS09340
gene id: 1743168:A8O14_RS09340
uniprot id: A0A191UH78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1743168:A8O14 RS04055
gene id: 1743168:A8O14_RS04055
uniprot id: A0A191UE50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1743168:A8O14 RS07335
gene id: 1743168:A8O14_RS07335
uniprot id: A0A191UG61
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS07160
gene id: 1743168:A8O14_RS07160
uniprot id: A0A191UG24
names: Similarity
messages: Belongs to the DEAD box helicase family.

1743168:A8O14 RS05645
gene id: 1743168:A8O14_RS05645
uniprot id: A0A191UF93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS05000
gene id: 1743168:A8O14_RS05000
uniprot id: A0A191UEM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS00100
gene id: 1743168:A8O14_RS00100
uniprot id: A0A191UCF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1743168:A8O14 RS11445
gene id: 1743168:A8O14_RS11445
uniprot id: A0A191UIA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1743168:A8O14 RS00375
gene id: 1743168:A8O14_RS00375
uniprot id: A0A191UCC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1743168:A8O14 RS05360
gene id: 1743168:A8O14_RS05360
uniprot id: A0A191UEW5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1743168:A8O14 RS08230
gene id: 1743168:A8O14_RS08230
uniprot id: A0A191UGL4
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1743168:A8O14 RS00555
gene id: 1743168:A8O14_RS00555
uniprot id: A0A191UCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS09610
gene id: 1743168:A8O14_RS09610
uniprot id: A0A191UH54
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS02490
gene id: 1743168:A8O14_RS02490
uniprot id: A0A191UDU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1743168:A8O14 RS04970
gene id: 1743168:A8O14_RS04970
uniprot id: A0A191UF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS04555
gene id: 1743168:A8O14_RS04555
uniprot id: A0A191UEE7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1743168:A8O14 RS00415
gene id: 1743168:A8O14_RS00415
uniprot id: A0A191UCT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1743168:A8O14 RS03475
gene id: 1743168:A8O14_RS03475
uniprot id: A0A191UDV7
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1743168:A8O14 RS02150
gene id: 1743168:A8O14_RS02150
uniprot id: A0A191UD75
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1743168:A8O14 RS00105
gene id: 1743168:A8O14_RS00105
uniprot id: A0A191UC83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1743168:A8O14 RS00880
gene id: 1743168:A8O14_RS00880
uniprot id: A0A191UCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1743168:A8O14 RS07630
gene id: 1743168:A8O14_RS07630
uniprot id: A0A191UGB0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1743168:A8O14 RS04200
gene id: 1743168:A8O14_RS04200
uniprot id: A0A191UEC7
names: Similarity
messages: Belongs to the peptidase S11 family.

1743168:A8O14 RS00090
gene id: 1743168:A8O14_RS00090
uniprot id: A0A191UCM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1743168:A8O14 RS04375
gene id: 1743168:A8O14_RS04375
uniprot id: A0A191UEA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1743168:A8O14 RS10585
gene id: 1743168:A8O14_RS10585
uniprot id: A0A191UHU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1743168:A8O14 RS01740
gene id: 1743168:A8O14_RS01740
uniprot id: A0A191UDG0
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1743168:A8O14 RS05835
gene id: 1743168:A8O14_RS05835
uniprot id: A0A191UFG1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1743168:A8O14 RS10295
gene id: 1743168:A8O14_RS10295
uniprot id: A0A191UHD7
names: Subcellular Location Annotation
messages: Periplasm

1743168:A8O14 RS02360
gene id: 1743168:A8O14_RS02360
uniprot id: A0A191UDS3
names: Similarity
messages: Belongs to the HesB/IscA family.

1743168:A8O14 RS06710
gene id: 1743168:A8O14_RS06710
uniprot id: A0A191UFJ2
names: Similarity
messages: Belongs to the peptidase C40 family.

1743168:A8O14 RS09060
gene id: 1743168:A8O14_RS09060
uniprot id: A0A191UGV7
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS07650
gene id: 1743168:A8O14_RS07650
uniprot id: A0A191UG09
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1743168:A8O14 RS04935
gene id: 1743168:A8O14_RS04935
uniprot id: A0A191UEQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1743168:A8O14 RS04710
gene id: 1743168:A8O14_RS04710
uniprot id: A0A191UEZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1743168:A8O14 RS07915
gene id: 1743168:A8O14_RS07915
uniprot id: A0A191UGB6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1743168:A8O14 RS04600
gene id: 1743168:A8O14_RS04600
uniprot id: A0A191UEX2
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1743168:A8O14 RS06270
gene id: 1743168:A8O14_RS06270
uniprot id: A0A191UFA5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1743168:A8O14 RS05305
gene id: 1743168:A8O14_RS05305
uniprot id: A0A191UF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1743168:A8O14 RS07005
gene id: 1743168:A8O14_RS07005
uniprot id: A0A191UFP1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1743168:A8O14 RS03065
gene id: 1743168:A8O14_RS03065
uniprot id: A0A191UDS6
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS04020
gene id: 1743168:A8O14_RS04020
uniprot id: A0A191UEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1743168:A8O14 RS01770
gene id: 1743168:A8O14_RS01770
uniprot id: A0A191UDG5
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS04310
gene id: 1743168:A8O14_RS04310
uniprot id: A0A191UEQ9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1743168:A8O14 RS04960
gene id: 1743168:A8O14_RS04960
uniprot id: A0A191UEM2
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1743168:A8O14 RS06635
gene id: 1743168:A8O14_RS06635
uniprot id: A0A191UFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS04910
gene id: 1743168:A8O14_RS04910
uniprot id: A0A191UF12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1743168:A8O14 RS00085
gene id: 1743168:A8O14_RS00085
uniprot id: A0A191UCA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1743168:A8O14 RS04515
gene id: 1743168:A8O14_RS04515
uniprot id: A0A191UEP9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1743168:A8O14 RS00910
gene id: 1743168:A8O14_RS00910
uniprot id: A0A191UCN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1743168:A8O14 RS00755
gene id: 1743168:A8O14_RS00755
uniprot id: A0A191UCR8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1743168:A8O14 RS04355
gene id: 1743168:A8O14_RS04355
uniprot id: A0A191UEF9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS06845
gene id: 1743168:A8O14_RS06845
uniprot id: A0A191UFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS00835
gene id: 1743168:A8O14_RS00835
uniprot id: A0A191UCS8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1743168:A8O14 RS00950
gene id: 1743168:A8O14_RS00950
uniprot id: A0A191UCV0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1743168:A8O14 RS00935
gene id: 1743168:A8O14_RS00935
uniprot id: A0A191UCP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1743168:A8O14 RS00450
gene id: 1743168:A8O14_RS00450
uniprot id: A0A191UCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS02495
gene id: 1743168:A8O14_RS02495
uniprot id: A0A191UDN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1743168:A8O14 RS09565
gene id: 1743168:A8O14_RS09565
uniprot id: A0A191UH04
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1743168:A8O14 RS09900
gene id: 1743168:A8O14_RS09900
uniprot id: A0A191UHH9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1743168:A8O14 RS04980
gene id: 1743168:A8O14_RS04980
uniprot id: A0A191UF32
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1743168:A8O14 RS07730
gene id: 1743168:A8O14_RS07730
uniprot id: A0A191UG82
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1743168:A8O14 RS10755
gene id: 1743168:A8O14_RS10755
uniprot id: A0A191UHM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1743168:A8O14 RS01650
gene id: 1743168:A8O14_RS01650
uniprot id: A0A191UDE8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1743168:A8O14 RS04775
gene id: 1743168:A8O14_RS04775
uniprot id: A0A191UEI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1743168:A8O14 RS09830
gene id: 1743168:A8O14_RS09830
uniprot id: A0A191UHG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1743168:A8O14 RS06425
gene id: 1743168:A8O14_RS06425
uniprot id: A0A191UFL8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS02240
gene id: 1743168:A8O14_RS02240
uniprot id: A0A191UDQ5
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1743168:A8O14 RS02570
gene id: 1743168:A8O14_RS02570
uniprot id: A0A191UDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1743168:A8O14 RS00990
gene id: 1743168:A8O14_RS00990
uniprot id: A0A191UD23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1743168:A8O14 RS00745
gene id: 1743168:A8O14_RS00745
uniprot id: A0A191UCY3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1743168:A8O14 RS05825
gene id: 1743168:A8O14_RS05825
uniprot id: A0A191UF33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1743168:A8O14 RS09080
gene id: 1743168:A8O14_RS09080
uniprot id: A0A191UH36
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1743168:A8O14 RS09390
gene id: 1743168:A8O14_RS09390
uniprot id: A0A191UGX3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1743168:A8O14 RS02480
gene id: 1743168:A8O14_RS02480
uniprot id: A0A191UDG9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1743168:A8O14 RS00820
gene id: 1743168:A8O14_RS00820
uniprot id: A0A191UCM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1743168:A8O14 RS00905
gene id: 1743168:A8O14_RS00905
uniprot id: A0A191UCL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1743168:A8O14 RS03580
gene id: 1743168:A8O14_RS03580
uniprot id: A0A191UE24
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS01950
gene id: 1743168:A8O14_RS01950
uniprot id: A0A191UDJ6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1743168:A8O14 RS01510
gene id: 1743168:A8O14_RS01510
uniprot id: A0A191UDC3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS00725
gene id: 1743168:A8O14_RS00725
uniprot id: A0A191UCZ1
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS08055
gene id: 1743168:A8O14_RS08055
uniprot id: A0A191UGJ2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1743168:A8O14 RS00430
gene id: 1743168:A8O14_RS00430
uniprot id: A0A191UCG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1743168:A8O14 RS03085
gene id: 1743168:A8O14_RS03085
uniprot id: A0A191UDN4
names: Similarity
messages: Belongs to the UPF0111 family.

1743168:A8O14 RS10955
gene id: 1743168:A8O14_RS10955
uniprot id: A0A191UHR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS01000
gene id: 1743168:A8O14_RS01000
uniprot id: A0A191UCW0
names: Similarity
messages: Belongs to the peptidase A24 family.

1743168:A8O14 RS01035
gene id: 1743168:A8O14_RS01035
uniprot id: A0A191UCN5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1743168:A8O14 RS04780
gene id: 1743168:A8O14_RS04780
uniprot id: A0A191UEM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1743168:A8O14 RS07660
gene id: 1743168:A8O14_RS07660
uniprot id: A0A191UGB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1743168:A8O14 RS06665
gene id: 1743168:A8O14_RS06665
uniprot id: A0A191UFU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1743168:A8O14 RS11455
gene id: 1743168:A8O14_RS11455
uniprot id: A0A191UIA2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1743168:A8O14 RS10490
gene id: 1743168:A8O14_RS10490
uniprot id: A0A191UHH0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1743168:A8O14 RS06545
gene id: 1743168:A8O14_RS06545
uniprot id: A0A191UFS8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1743168:A8O14 RS01960
gene id: 1743168:A8O14_RS01960
uniprot id: A0A191UD39
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1743168:A8O14 RS08745
gene id: 1743168:A8O14_RS08745
uniprot id: A0A191UGZ3
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS09260
gene id: 1743168:A8O14_RS09260
uniprot id: A0A191UH67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1743168:A8O14 RS08140
gene id: 1743168:A8O14_RS08140
uniprot id: A0A191UGJ9
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS04175
gene id: 1743168:A8O14_RS04175
uniprot id: A0A191UEC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS05425
gene id: 1743168:A8O14_RS05425
uniprot id: A0A191UEX0
names: Subcellular Location Annotation
messages: Cytoplasm

1743168:A8O14 RS00265
gene id: 1743168:A8O14_RS00265
uniprot id: A0A191UCH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1743168:A8O14 RS01890
gene id: 1743168:A8O14_RS01890
uniprot id: A0A191UDI5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1743168:A8O14 RS08185
gene id: 1743168:A8O14_RS08185
uniprot id: A0A191UGB9
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1743168:A8O14 RS05475
gene id: 1743168:A8O14_RS05475
uniprot id: A0A191UEX6
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.

1743168:A8O14 RS04130
gene id: 1743168:A8O14_RS04130
uniprot id: A0A191UEM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1743168:A8O14 RS06865
gene id: 1743168:A8O14_RS06865
uniprot id: A0A191UFY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1743168:A8O14 RS11145
gene id: 1743168:A8O14_RS11145
uniprot id: A0A191UI53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1743168:A8O14 RS04035
gene id: 1743168:A8O14_RS04035
uniprot id: A0A191UE94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1743168:A8O14 RS05850
gene id: 1743168:A8O14_RS05850
uniprot id: A0A191UF42
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1743168:A8O14 RS02005
gene id: 1743168:A8O14_RS02005
uniprot id: A0A191UDE0
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1743168:A8O14 RS09940
gene id: 1743168:A8O14_RS09940
uniprot id: A0A191UH73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1743168:A8O14 RS06250
gene id: 1743168:A8O14_RS06250
uniprot id: A0A191UFN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1743168:A8O14 RS04415
gene id: 1743168:A8O14_RS04415
uniprot id: A0A191UEG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1743168:A8O14 RS08465
gene id: 1743168:A8O14_RS08465
uniprot id: A0A191UGH3
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS01515
gene id: 1743168:A8O14_RS01515
uniprot id: A0A191UD52
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1743168:A8O14 RS01560
gene id: 1743168:A8O14_RS01560
uniprot id: A0A191UDC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1743168:A8O14 RS08040
gene id: 1743168:A8O14_RS08040
uniprot id: A0A191UGE0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1743168:A8O14 RS08780
gene id: 1743168:A8O14_RS08780
uniprot id: A0A191UGQ9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1743168:A8O14 RS08460
gene id: 1743168:A8O14_RS08460
uniprot id: A0A191UGH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1743168:A8O14 RS00280
gene id: 1743168:A8O14_RS00280
uniprot id: A0A191UCP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1743168:A8O14 RS03020
gene id: 1743168:A8O14_RS03020
uniprot id: A0A191UE40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS02135
gene id: 1743168:A8O14_RS02135
uniprot id: A0A191UDM8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1743168:A8O14 RS02870
gene id: 1743168:A8O14_RS02870
uniprot id: A0A191UDU7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1743168:A8O14 RS11150
gene id: 1743168:A8O14_RS11150
uniprot id: A0A191UHV7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1743168:A8O14 RS05065
gene id: 1743168:A8O14_RS05065
uniprot id: A0A191UES1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS09160
gene id: 1743168:A8O14_RS09160
uniprot id: A0A191UH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1743168:A8O14 RS04625
gene id: 1743168:A8O14_RS04625
uniprot id: A0A191UEX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS01555
gene id: 1743168:A8O14_RS01555
uniprot id: A0A191UD02
names: Similarity
messages: Belongs to the YoeB family.

1743168:A8O14 RS00600
gene id: 1743168:A8O14_RS00600
uniprot id: A0A191UCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1743168:A8O14 RS00340
gene id: 1743168:A8O14_RS00340
uniprot id: A0A191UCR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1743168:A8O14 RS01245
gene id: 1743168:A8O14_RS01245
uniprot id: A0A191UI44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1743168:A8O14 RS00500
gene id: 1743168:A8O14_RS00500
uniprot id: A0A191UCE4
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1743168:A8O14 RS02460
gene id: 1743168:A8O14_RS02460
uniprot id: A0A191UDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1743168:A8O14 RS05255
gene id: 1743168:A8O14_RS05255
uniprot id: A0A191UEV1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1743168:A8O14 RS03560
gene id: 1743168:A8O14_RS03560
uniprot id: A0A191UED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS09880
gene id: 1743168:A8O14_RS09880
uniprot id: A0A191UH65
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1743168:A8O14 RS07685
gene id: 1743168:A8O14_RS07685
uniprot id: A0A191UG20
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1743168:A8O14 RS08210
gene id: 1743168:A8O14_RS08210
uniprot id: A0A191UGC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1743168:A8O14 RS07635
gene id: 1743168:A8O14_RS07635
uniprot id: A0A191UGB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1743168:A8O14 RS00435
gene id: 1743168:A8O14_RS00435
uniprot id: A0A191UCS6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1743168:A8O14 RS07920
gene id: 1743168:A8O14_RS07920
uniprot id: A0A191UG60
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1743168:A8O14 RS07455
gene id: 1743168:A8O14_RS07455
uniprot id: A0A191UFX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1743168:A8O14 RS02100
gene id: 1743168:A8O14_RS02100
uniprot id: A0A191UDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1743168:A8O14 RS05165
gene id: 1743168:A8O14_RS05165
uniprot id: A0A191UET7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1743168:A8O14 RS08135
gene id: 1743168:A8O14_RS08135
uniprot id: A0A191UGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1743168:A8O14 RS00580
gene id: 1743168:A8O14_RS00580
uniprot id: A0A191UCI7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1743168:A8O14 RS00385
gene id: 1743168:A8O14_RS00385
uniprot id: A0A191UCR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1743168:A8O14 RS02535
gene id: 1743168:A8O14_RS02535
uniprot id: A0A191UI68
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1743168:A8O14 RS09550
gene id: 1743168:A8O14_RS09550
uniprot id: A0A191UHB9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1743168:A8O14 RS01380
gene id: 1743168:A8O14_RS01380
uniprot id: A0A191UCX2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1743168:A8O14 RS01910
gene id: 1743168:A8O14_RS01910
uniprot id: A0A191UDI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1743168:A8O14 RS05285
gene id: 1743168:A8O14_RS05285
uniprot id: A0A191UF36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1743168:A8O14 RS01265
gene id: 1743168:A8O14_RS01265
uniprot id: A0A191UCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1743168:A8O14 RS09655
gene id: 1743168:A8O14_RS09655
uniprot id: A0A191UHF1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS09660
gene id: 1743168:A8O14_RS09660
uniprot id: A0A191UHD9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1743168:A8O14 RS07000
gene id: 1743168:A8O14_RS07000
uniprot id: A0A191UFP3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1743168:A8O14 RS06590
gene id: 1743168:A8O14_RS06590
uniprot id: A0A191UFP2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1743168:A8O14 RS05985
gene id: 1743168:A8O14_RS05985
uniprot id: A0A191UFI9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1743168:A8O14 RS03455
gene id: 1743168:A8O14_RS03455
uniprot id: A0A191UE03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1743168:A8O14 RS08205
gene id: 1743168:A8O14_RS08205
uniprot id: A0A191UGG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1743168:A8O14 RS04345
gene id: 1743168:A8O14_RS04345
uniprot id: A0A191UEL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS10560
gene id: 1743168:A8O14_RS10560
uniprot id: A0A191UHU1
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS09150
gene id: 1743168:A8O14_RS09150
uniprot id: A0A191UGV1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1743168:A8O14 RS06680
gene id: 1743168:A8O14_RS06680
uniprot id: A0A191UIE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1743168:A8O14 RS10815
gene id: 1743168:A8O14_RS10815
uniprot id: A0A191UHN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Periplasm
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1743168:A8O14 RS01005
gene id: 1743168:A8O14_RS01005
uniprot id: A0A191UCN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1743168:A8O14 RS00135
gene id: 1743168:A8O14_RS00135
uniprot id: A0A191UCB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1743168:A8O14 RS07015
gene id: 1743168:A8O14_RS07015
uniprot id: A0A191UG01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1743168:A8O14 RS10920
gene id: 1743168:A8O14_RS10920
uniprot id: A0A191UI12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1743168:A8O14 RS03030
gene id: 1743168:A8O14_RS03030
uniprot id: A0A191UDM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1743168:A8O14 RS09645
gene id: 1743168:A8O14_RS09645
uniprot id: A0A191UH14
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1743168:A8O14 RS02320
gene id: 1743168:A8O14_RS02320
uniprot id: A0A191UDE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1743168:A8O14 RS05800
gene id: 1743168:A8O14_RS05800
uniprot id: A0A191UF29
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1743168:A8O14 RS06015
gene id: 1743168:A8O14_RS06015
uniprot id: A0A191UFJ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1743168:A8O14 RS10080
gene id: 1743168:A8O14_RS10080
uniprot id: A0A191UHM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1743168:A8O14 RS02510
gene id: 1743168:A8O14_RS02510
uniprot id: A0A191UDU6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1743168:A8O14 RS01935
gene id: 1743168:A8O14_RS01935
uniprot id: A0A191UD67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS08660
gene id: 1743168:A8O14_RS08660
uniprot id: A0A191UGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS00775
gene id: 1743168:A8O14_RS00775
uniprot id: A0A191UI15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1743168:A8O14 RS08190
gene id: 1743168:A8O14_RS08190
uniprot id: A0A191UGB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS01395
gene id: 1743168:A8O14_RS01395
uniprot id: A0A191UD30
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1743168:A8O14 RS08015
gene id: 1743168:A8O14_RS08015
uniprot id: A0A191UGD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS00370
gene id: 1743168:A8O14_RS00370
uniprot id: A0A191UCJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1743168:A8O14 RS04390
gene id: 1743168:A8O14_RS04390
uniprot id: A0A191UES3
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS06785
gene id: 1743168:A8O14_RS06785
uniprot id: A0A191UFS6
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS03730
gene id: 1743168:A8O14_RS03730
uniprot id: A0A191UEG2
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1743168:A8O14 RS02025
gene id: 1743168:A8O14_RS02025
uniprot id: A0A191UDL2
names: Similarity
messages: Belongs to the fabD family.

1743168:A8O14 RS10870
gene id: 1743168:A8O14_RS10870
uniprot id: A0A191UHR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1743168:A8O14 RS02090
gene id: 1743168:A8O14_RS02090
uniprot id: A0A191UDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1743168:A8O14 RS10030
gene id: 1743168:A8O14_RS10030
uniprot id: A0A191UHL4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1743168:A8O14 RS10805
gene id: 1743168:A8O14_RS10805
uniprot id: A0A191UHZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1743168:A8O14 RS02760
gene id: 1743168:A8O14_RS02760
uniprot id: A0A191UDZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1743168:A8O14 RS00575
gene id: 1743168:A8O14_RS00575
uniprot id: A0A191UCF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1743168:A8O14 RS00075
gene id: 1743168:A8O14_RS00075
uniprot id: A0A191UCF0
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1743168:A8O14 RS01860
gene id: 1743168:A8O14_RS01860
uniprot id: A0A191UDH3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1743168:A8O14 RS03395
gene id: 1743168:A8O14_RS03395
uniprot id: A0A191UE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS10505
gene id: 1743168:A8O14_RS10505
uniprot id: A0A191UHK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1743168:A8O14 RS08850
gene id: 1743168:A8O14_RS08850
uniprot id: A0A191UH06
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1743168:A8O14 RS00345
gene id: 1743168:A8O14_RS00345
uniprot id: A0A191UCI9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1743168:A8O14 RS02925
gene id: 1743168:A8O14_RS02925
uniprot id: A0A191UDK6
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1743168:A8O14 RS01295
gene id: 1743168:A8O14_RS01295
uniprot id: A0A191UD76
names: Similarity
messages: Belongs to the DNA photolyase family.

1743168:A8O14 RS10910
gene id: 1743168:A8O14_RS10910
uniprot id: A0A191UIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1743168:A8O14 RS11125
gene id: 1743168:A8O14_RS11125
uniprot id: A0A191UHU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1743168:A8O14 RS07100
gene id: 1743168:A8O14_RS07100
uniprot id: A0A191UIF9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS11115
gene id: 1743168:A8O14_RS11115
uniprot id: A0A191UHV4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1743168:A8O14 RS00015
gene id: 1743168:A8O14_RS00015
uniprot id: A0A191UCL9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1743168:A8O14 RS06760
gene id: 1743168:A8O14_RS06760
uniprot id: A0A191UFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS03075
gene id: 1743168:A8O14_RS03075
uniprot id: A0A191UE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1743168:A8O14 RS02755
gene id: 1743168:A8O14_RS02755
uniprot id: A0A191UDY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1743168:A8O14 RS00735
gene id: 1743168:A8O14_RS00735
uniprot id: A0A191UCI8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1743168:A8O14 RS07360
gene id: 1743168:A8O14_RS07360
uniprot id: A0A191UIE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1743168:A8O14 RS04170
gene id: 1743168:A8O14_RS04170
uniprot id: A0A191UE68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS08990
gene id: 1743168:A8O14_RS08990
uniprot id: A0A191UH25
names: Similarity
messages: Belongs to the UPF0173 family.

1743168:A8O14 RS03625
gene id: 1743168:A8O14_RS03625
uniprot id: A0A191UEE5
names: Similarity
messages: Belongs to the thioredoxin family.

1743168:A8O14 RS04735
gene id: 1743168:A8O14_RS04735
uniprot id: A0A191UEX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1743168:A8O14 RS04795
gene id: 1743168:A8O14_RS04795
uniprot id: A0A191UF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1743168:A8O14 RS03980
gene id: 1743168:A8O14_RS03980
uniprot id: A0A191UE87
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1743168:A8O14 RS00460
gene id: 1743168:A8O14_RS00460
uniprot id: A0A191UCG7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1743168:A8O14 RS09990
gene id: 1743168:A8O14_RS09990
uniprot id: A0A191UHB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1743168:A8O14 RS01410
gene id: 1743168:A8O14_RS01410
uniprot id: A0A191UCX6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1743168:A8O14 RS09770
gene id: 1743168:A8O14_RS09770
uniprot id: A0A191UHH4
names: Similarity
messages: Belongs to the UPF0162 family.

1743168:A8O14 RS09865
gene id: 1743168:A8O14_RS09865
uniprot id: A0A191UHH5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1743168:A8O14 RS06890
gene id: 1743168:A8O14_RS06890
uniprot id: A0A191UFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS01145
gene id: 1743168:A8O14_RS01145
uniprot id: A0A191UCT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1743168:A8O14 RS00895
gene id: 1743168:A8O14_RS00895
uniprot id: A0A191UD16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1743168:A8O14 RS10035
gene id: 1743168:A8O14_RS10035
uniprot id: A0A191UHJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1743168:A8O14 RS00915
gene id: 1743168:A8O14_RS00915
uniprot id: A0A191UD09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS09640
gene id: 1743168:A8O14_RS09640
uniprot id: A0A191UH60
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1743168:A8O14 RS02500
gene id: 1743168:A8O14_RS02500
uniprot id: A0A191UDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1743168:A8O14 RS09845
gene id: 1743168:A8O14_RS09845
uniprot id: A0A191UIK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS09625
gene id: 1743168:A8O14_RS09625
uniprot id: A0A191UHE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1743168:A8O14 RS01765
gene id: 1743168:A8O14_RS01765
uniprot id: A0A191UDF8
names: Similarity
messages: Belongs to the leucine-binding protein family.

1743168:A8O14 RS11190
gene id: 1743168:A8O14_RS11190
uniprot id: A0A191UHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1743168:A8O14 RS06740
gene id: 1743168:A8O14_RS06740
uniprot id: A0A191UFJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1743168:A8O14 RS08475
gene id: 1743168:A8O14_RS08475
uniprot id: A0A191UGR4
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

1743168:A8O14 RS05040
gene id: 1743168:A8O14_RS05040
uniprot id: A0A191UF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1743168:A8O14 RS10680
gene id: 1743168:A8O14_RS10680
uniprot id: A0A191UHL5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1743168:A8O14 RS02875
gene id: 1743168:A8O14_RS02875
uniprot id: A0A191UDJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1743168:A8O14 RS09905
gene id: 1743168:A8O14_RS09905
uniprot id: A0A191UH98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1743168:A8O14 RS02370
gene id: 1743168:A8O14_RS02370
uniprot id: A0A191UDB1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1743168:A8O14 RS04690
gene id: 1743168:A8O14_RS04690
uniprot id: A0A191UET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1743168:A8O14 RS03555
gene id: 1743168:A8O14_RS03555
uniprot id: A0A191UED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS01220
gene id: 1743168:A8O14_RS01220
uniprot id: A0A191UCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1743168:A8O14 RS05375
gene id: 1743168:A8O14_RS05375
uniprot id: A0A191UF49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1743168:A8O14 RS01885
gene id: 1743168:A8O14_RS01885
uniprot id: A0A191UDH8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1743168:A8O14 RS04680
gene id: 1743168:A8O14_RS04680
uniprot id: A0A191UEW8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS10635
gene id: 1743168:A8O14_RS10635
uniprot id: A0A191UHV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1743168:A8O14 RS00805
gene id: 1743168:A8O14_RS00805
uniprot id: A0A191UD01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS01155
gene id: 1743168:A8O14_RS01155
uniprot id: A0A191UD64
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1743168:A8O14 RS02865
gene id: 1743168:A8O14_RS02865
uniprot id: A0A191UE08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1743168:A8O14 RS03660
gene id: 1743168:A8O14_RS03660
uniprot id: A0A191UEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS07030
gene id: 1743168:A8O14_RS07030
uniprot id: A0A191UFP8
names: Similarity
messages: Belongs to the P(II) protein family.

1743168:A8O14 RS01250
gene id: 1743168:A8O14_RS01250
uniprot id: A0A191UD79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1743168:A8O14 RS07350
gene id: 1743168:A8O14_RS07350
uniprot id: A0A191UFV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1743168:A8O14 RS07985
gene id: 1743168:A8O14_RS07985
uniprot id: A0A191UGH1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1743168:A8O14 RS10525
gene id: 1743168:A8O14_RS10525
uniprot id: A0A191UHV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1743168:A8O14 RS07125
gene id: 1743168:A8O14_RS07125
uniprot id: A0A191UFR2
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1743168:A8O14 RS06985
gene id: 1743168:A8O14_RS06985
uniprot id: A0A191UG07
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS02065
gene id: 1743168:A8O14_RS02065
uniprot id: A0A191UD96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1743168:A8O14 RS10475
gene id: 1743168:A8O14_RS10475
uniprot id: A0A191UHS7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1743168:A8O14 RS07745
gene id: 1743168:A8O14_RS07745
uniprot id: A0A191UGD2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1743168:A8O14 RS09045
gene id: 1743168:A8O14_RS09045
uniprot id: A0A191UH38
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1743168:A8O14 RS08610
gene id: 1743168:A8O14_RS08610
uniprot id: A0A191UGW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS01550
gene id: 1743168:A8O14_RS01550
uniprot id: A0A191UCX1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1743168:A8O14 RS04100
gene id: 1743168:A8O14_RS04100
uniprot id: A0A191UEM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1743168:A8O14 RS00610
gene id: 1743168:A8O14_RS00610
uniprot id: A0A191UCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1743168:A8O14 RS09895
gene id: 1743168:A8O14_RS09895
uniprot id: A0A191UHJ0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1743168:A8O14 RS04430
gene id: 1743168:A8O14_RS04430
uniprot id: A0A191UEN4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1743168:A8O14 RS01545
gene id: 1743168:A8O14_RS01545
uniprot id: A0A191UD57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1743168:A8O14 RS07765
gene id: 1743168:A8O14_RS07765
uniprot id: A0A191UG34
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1743168:A8O14 RS00405
gene id: 1743168:A8O14_RS00405
uniprot id: A0A191UCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1743168:A8O14 RS02890
gene id: 1743168:A8O14_RS02890
uniprot id: A0A191UE13
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1743168:A8O14 RS01030
gene id: 1743168:A8O14_RS01030
uniprot id: A0A191UI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1743168:A8O14 RS01235
gene id: 1743168:A8O14_RS01235
uniprot id: A0A191UI28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS07450
gene id: 1743168:A8O14_RS07450
uniprot id: A0A191UG37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1743168:A8O14 RS03035
gene id: 1743168:A8O14_RS03035
uniprot id: A0A191UDR9
names: Similarity
messages: Belongs to the peptidase S66 family.

1743168:A8O14 RS03060
gene id: 1743168:A8O14_RS03060
uniprot id: A0A191UDM9
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS04455
gene id: 1743168:A8O14_RS04455
uniprot id: A0A191UEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1743168:A8O14 RS01055
gene id: 1743168:A8O14_RS01055
uniprot id: A0A191UCW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1743168:A8O14 RS02255
gene id: 1743168:A8O14_RS02255
uniprot id: A0A191UDD2
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS09785
gene id: 1743168:A8O14_RS09785
uniprot id: A0A191UH80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1743168:A8O14 RS02205
gene id: 1743168:A8O14_RS02205
uniprot id: A0A191UDC2
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS10440
gene id: 1743168:A8O14_RS10440
uniprot id: A0A191UHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1743168:A8O14 RS00455
gene id: 1743168:A8O14_RS00455
uniprot id: A0A191UIB2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1743168:A8O14 RS00940
gene id: 1743168:A8O14_RS00940
uniprot id: A0A191UD13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1743168:A8O14 RS05245
gene id: 1743168:A8O14_RS05245
uniprot id: A0A191UF31
names: Similarity
messages: Belongs to the hyi family.

1743168:A8O14 RS05585
gene id: 1743168:A8O14_RS05585
uniprot id: A0A191UF85
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS08045
gene id: 1743168:A8O14_RS08045
uniprot id: A0A191UG90
names: Similarity
messages: Belongs to the DapA family.

1743168:A8O14 RS05485
gene id: 1743168:A8O14_RS05485
uniprot id: A0A191UFA3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1743168:A8O14 RS08200
gene id: 1743168:A8O14_RS08200
uniprot id: A0A191UGK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1743168:A8O14 RS04895
gene id: 1743168:A8O14_RS04895
uniprot id: A0A191UEX1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1743168:A8O14 RS02430
gene id: 1743168:A8O14_RS02430
uniprot id: A0A191UDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS02915
gene id: 1743168:A8O14_RS02915
uniprot id: A0A191UE20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1743168:A8O14 RS01620
gene id: 1743168:A8O14_RS01620
uniprot id: A0A191UDD1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1743168:A8O14 RS08180
gene id: 1743168:A8O14_RS08180
uniprot id: A0A191UGG3
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1743168:A8O14 RS03925
gene id: 1743168:A8O14_RS03925
uniprot id: A0A191UEJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1743168:A8O14 RS03755
gene id: 1743168:A8O14_RS03755
uniprot id: A0A191UE51
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS05745
gene id: 1743168:A8O14_RS05745
uniprot id: A0A191UFE3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1743168:A8O14 RS03955
gene id: 1743168:A8O14_RS03955
uniprot id: A0A191UEK0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1743168:A8O14 RS02225
gene id: 1743168:A8O14_RS02225
uniprot id: A0A191UD88
names: Similarity
messages: Belongs to the threonine synthase family.

1743168:A8O14 RS08720
gene id: 1743168:A8O14_RS08720
uniprot id: A0A191UGW1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1743168:A8O14 RS09935
gene id: 1743168:A8O14_RS09935
uniprot id: A0A191UH77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1743168:A8O14 RS01050
gene id: 1743168:A8O14_RS01050
uniprot id: A0A191UD45
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1743168:A8O14 RS02930
gene id: 1743168:A8O14_RS02930
uniprot id: A0A191UDP9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1743168:A8O14 RS02540
gene id: 1743168:A8O14_RS02540
uniprot id: A0A191UDV1
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS04300
gene id: 1743168:A8O14_RS04300
uniprot id: A0A191UE97
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1743168:A8O14 RS07485
gene id: 1743168:A8O14_RS07485
uniprot id: A0A191UFX8
names: Similarity
messages: Belongs to the TPP enzyme family.

1743168:A8O14 RS10640
gene id: 1743168:A8O14_RS10640
uniprot id: A0A191UHM8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1743168:A8O14 RS10340
gene id: 1743168:A8O14_RS10340
uniprot id: A0A191UHQ0
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS02050
gene id: 1743168:A8O14_RS02050
uniprot id: A0A191UDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1743168:A8O14 RS08615
gene id: 1743168:A8O14_RS08615
uniprot id: A0A191UGT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1743168:A8O14 RS10100
gene id: 1743168:A8O14_RS10100
uniprot id: A0A191UHA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1743168:A8O14 RS07490
gene id: 1743168:A8O14_RS07490
uniprot id: A0A191UFY0
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

1743168:A8O14 RS05135
gene id: 1743168:A8O14_RS05135
uniprot id: A0A191UEQ0
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS06440
gene id: 1743168:A8O14_RS06440
uniprot id: A0A191UFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1743168:A8O14 RS05175
gene id: 1743168:A8O14_RS05175
uniprot id: A0A191UF66
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1743168:A8O14 RS02355
gene id: 1743168:A8O14_RS02355
uniprot id: A0A191UDR7
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1743168:A8O14 RS09700
gene id: 1743168:A8O14_RS09700
uniprot id: A0A191UH69
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

1743168:A8O14 RS06480
gene id: 1743168:A8O14_RS06480
uniprot id: A0A191UFE7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1743168:A8O14 RS09875
gene id: 1743168:A8O14_RS09875
uniprot id: A0A191UH95
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1743168:A8O14 RS11010
gene id: 1743168:A8O14_RS11010
uniprot id: A0A191UHS8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1743168:A8O14 RS05440
gene id: 1743168:A8O14_RS05440
uniprot id: A0A191UIC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1743168:A8O14 RS05805
gene id: 1743168:A8O14_RS05805
uniprot id: A0A191UFF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1743168:A8O14 RS09840
gene id: 1743168:A8O14_RS09840
uniprot id: A0A191UH57
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1743168:A8O14 RS10510
gene id: 1743168:A8O14_RS10510
uniprot id: A0A191UHH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS11470
gene id: 1743168:A8O14_RS11470
uniprot id: A0A191UHZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1743168:A8O14 RS03990
gene id: 1743168:A8O14_RS03990
uniprot id: A0A191UEK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1743168:A8O14 RS07700
gene id: 1743168:A8O14_RS07700
uniprot id: A0A191UG79
names: Similarity
messages: Belongs to the histone deacetylase family.

1743168:A8O14 RS03985
gene id: 1743168:A8O14_RS03985
uniprot id: A0A191UEK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1743168:A8O14 RS00625
gene id: 1743168:A8O14_RS00625
uniprot id: A0A191UCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1743168:A8O14 RS04295
gene id: 1743168:A8O14_RS04295
uniprot id: A0A191UEL0
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1743168:A8O14 RS06550
gene id: 1743168:A8O14_RS06550
uniprot id: A0A191UFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS05370
gene id: 1743168:A8O14_RS05370
uniprot id: A0A191UF94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1743168:A8O14 RS10765
gene id: 1743168:A8O14_RS10765
uniprot id: A0A191UHZ4
names: Similarity
messages: Belongs to the SCO1/2 family.

1743168:A8O14 RS06385
gene id: 1743168:A8O14_RS06385
uniprot id: A0A191UFP9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1743168:A8O14 RS08425
gene id: 1743168:A8O14_RS08425
uniprot id: A0A191UGP8
names: Similarity
messages: Belongs to the PucC family.

1743168:A8O14 RS08320
gene id: 1743168:A8O14_RS08320
uniprot id: A0A191UGI6
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

1743168:A8O14 RS05035
gene id: 1743168:A8O14_RS05035
uniprot id: A0A191UF30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1743168:A8O14 RS02935
gene id: 1743168:A8O14_RS02935
uniprot id: A0A191UE22
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1743168:A8O14 RS06670
gene id: 1743168:A8O14_RS06670
uniprot id: A0A191UFU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1743168:A8O14 RS10715
gene id: 1743168:A8O14_RS10715
uniprot id: A0A191UHZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1743168:A8O14 RS04950
gene id: 1743168:A8O14_RS04950
uniprot id: A0A191UF28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1743168:A8O14 RS10965
gene id: 1743168:A8O14_RS10965
uniprot id: A0A191UI32
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1743168:A8O14 RS04825
gene id: 1743168:A8O14_RS04825
uniprot id: A0A191UEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS07235
gene id: 1743168:A8O14_RS07235
uniprot id: A0A191UFZ7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1743168:A8O14 RS08480
gene id: 1743168:A8O14_RS08480
uniprot id: A0A191UGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1743168:A8O14 RS00765
gene id: 1743168:A8O14_RS00765
uniprot id: A0A191UIB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1743168:A8O14 RS07460
gene id: 1743168:A8O14_RS07460
uniprot id: A0A191UFX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1743168:A8O14 RS04065
gene id: 1743168:A8O14_RS04065
uniprot id: A0A191UEL8
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1743168:A8O14 RS04150
gene id: 1743168:A8O14_RS04150
uniprot id: A0A191UEB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1743168:A8O14 RS09480
gene id: 1743168:A8O14_RS09480
uniprot id: A0A191UGY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1743168:A8O14 RS01465
gene id: 1743168:A8O14_RS01465
uniprot id: A0A191UD40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1743168:A8O14 RS01580
gene id: 1743168:A8O14_RS01580
uniprot id: A0A191UD07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1743168:A8O14 RS00305
gene id: 1743168:A8O14_RS00305
uniprot id: A0A191UI21
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1743168:A8O14 RS02920
gene id: 1743168:A8O14_RS02920
uniprot id: A0A191UDV9
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1743168:A8O14 RS01085
gene id: 1743168:A8O14_RS01085
uniprot id: A0A191UCP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS10360
gene id: 1743168:A8O14_RS10360
uniprot id: A0A191UHS1
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS08555
gene id: 1743168:A8O14_RS08555
uniprot id: A0A191UGU7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1743168:A8O14 RS07295
gene id: 1743168:A8O14_RS07295
uniprot id: A0A191UFU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1743168:A8O14 RS09595
gene id: 1743168:A8O14_RS09595
uniprot id: A0A191UH20
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1743168:A8O14 RS08355
gene id: 1743168:A8O14_RS08355
uniprot id: A0A191UGE5
names: Function
names: PTM
messages: Binds 4 heme groups per subunit.
messages: The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.

1743168:A8O14 RS09485
gene id: 1743168:A8O14_RS09485
uniprot id: A0A191UGZ8
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1743168:A8O14 RS07240
gene id: 1743168:A8O14_RS07240
uniprot id: A0A191UFT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS01090
gene id: 1743168:A8O14_RS01090
uniprot id: A0A191UCS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1743168:A8O14 RS02860
gene id: 1743168:A8O14_RS02860
uniprot id: A0A191UE07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1743168:A8O14 RS01495
gene id: 1743168:A8O14_RS01495
uniprot id: A0A191UCW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1743168:A8O14 RS01520
gene id: 1743168:A8O14_RS01520
uniprot id: A0A191UCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1743168:A8O14 RS08945
gene id: 1743168:A8O14_RS08945
uniprot id: A0A191UGU0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1743168:A8O14 RS04955
gene id: 1743168:A8O14_RS04955
uniprot id: A0A191UEY0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1743168:A8O14 RS07205
gene id: 1743168:A8O14_RS07205
uniprot id: A0A191UFZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS00855
gene id: 1743168:A8O14_RS00855
uniprot id: A0A191UD11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS08375
gene id: 1743168:A8O14_RS08375
uniprot id: A0A191UGN8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1743168:A8O14 RS03845
gene id: 1743168:A8O14_RS03845
uniprot id: A0A191UED0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1743168:A8O14 RS05740
gene id: 1743168:A8O14_RS05740
uniprot id: A0A191UF19
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1743168:A8O14 RS01420
gene id: 1743168:A8O14_RS01420
uniprot id: A0A191UDA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1743168:A8O14 RS08000
gene id: 1743168:A8O14_RS08000
uniprot id: A0A191UG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS08470
gene id: 1743168:A8O14_RS08470
uniprot id: A0A191UGT3
names: Similarity
messages: Belongs to the PucC family.

1743168:A8O14 RS01675
gene id: 1743168:A8O14_RS01675
uniprot id: A0A191UIE9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1743168:A8O14 RS06695
gene id: 1743168:A8O14_RS06695
uniprot id: A0A191UFV1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS04985
gene id: 1743168:A8O14_RS04985
uniprot id: A0A191UEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS02840
gene id: 1743168:A8O14_RS02840
uniprot id: A0A191UE04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1743168:A8O14 RS00130
gene id: 1743168:A8O14_RS00130
uniprot id: A0A191UC88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1743168:A8O14 RS03695
gene id: 1743168:A8O14_RS03695
uniprot id: A0A191UDY9
names: Similarity
messages: Belongs to the UxaA family.

1743168:A8O14 RS04335
gene id: 1743168:A8O14_RS04335
uniprot id: A0A191UER2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1743168:A8O14 RS07140
gene id: 1743168:A8O14_RS07140
uniprot id: A0A191UG31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS03470
gene id: 1743168:A8O14_RS03470
uniprot id: A0A191UE70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1743168:A8O14 RS02785
gene id: 1743168:A8O14_RS02785
uniprot id: A0A191UDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS07040
gene id: 1743168:A8O14_RS07040
uniprot id: A0A191UG05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS00565
gene id: 1743168:A8O14_RS00565
uniprot id: A0A191UCV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS07115
gene id: 1743168:A8O14_RS07115
uniprot id: A0A191UFX7
names: Similarity
messages: Belongs to the peptidase M1 family.

1743168:A8O14 RS06720
gene id: 1743168:A8O14_RS06720
uniprot id: A0A191UFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS01875
gene id: 1743168:A8O14_RS01875
uniprot id: A0A191UD24
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1743168:A8O14 RS10425
gene id: 1743168:A8O14_RS10425
uniprot id: A0A191UHJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1743168:A8O14 RS00380
gene id: 1743168:A8O14_RS00380
uniprot id: A0A191UCF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1743168:A8O14 RS05830
gene id: 1743168:A8O14_RS05830
uniprot id: A0A191UFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1743168:A8O14 RS10010
gene id: 1743168:A8O14_RS10010
uniprot id: A0A191UHJ3
names: Similarity
messages: Belongs to the peptidase S13 family.

1743168:A8O14 RS10840
gene id: 1743168:A8O14_RS10840
uniprot id: A0A191UHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1743168:A8O14 RS09525
gene id: 1743168:A8O14_RS09525
uniprot id: A0A191UH37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1743168:A8O14 RS05110
gene id: 1743168:A8O14_RS05110
uniprot id: A0A191UEP6
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS02395
gene id: 1743168:A8O14_RS02395
uniprot id: A0A191UDB6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1743168:A8O14 RS07280
gene id: 1743168:A8O14_RS07280
uniprot id: A0A191UG44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS11205
gene id: 1743168:A8O14_RS11205
uniprot id: A0A191UI65
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1743168:A8O14 RS04050
gene id: 1743168:A8O14_RS04050
uniprot id: A0A191UEG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1743168:A8O14 RS03710
gene id: 1743168:A8O14_RS03710
uniprot id: A0A191UEG0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1743168:A8O14 RS10355
gene id: 1743168:A8O14_RS10355
uniprot id: A0A191UHE8
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1743168:A8O14 RS03875
gene id: 1743168:A8O14_RS03875
uniprot id: A0A191UED3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1743168:A8O14 RS09930
gene id: 1743168:A8O14_RS09930
uniprot id: A0A191UHA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1743168:A8O14 RS02415
gene id: 1743168:A8O14_RS02415
uniprot id: A0A191UDL7
names: Similarity
messages: Belongs to the class-I fumarase family.

1743168:A8O14 RS04210
gene id: 1743168:A8O14_RS04210
uniprot id: A0A191UEP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1743168:A8O14 RS06355
gene id: 1743168:A8O14_RS06355
uniprot id: A0A191UFP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1743168:A8O14 RS05550
gene id: 1743168:A8O14_RS05550
uniprot id: A0A191UF76
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS01320
gene id: 1743168:A8O14_RS01320
uniprot id: A0A191UCW1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

1743168:A8O14 RS00290
gene id: 1743168:A8O14_RS00290
uniprot id: A0A191UCI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1743168:A8O14 RS05100
gene id: 1743168:A8O14_RS05100
uniprot id: A0A191UF53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1743168:A8O14 RS09630
gene id: 1743168:A8O14_RS09630
uniprot id: A0A191UHD5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1743168:A8O14 RS04360
gene id: 1743168:A8O14_RS04360
uniprot id: A0A191UER8
names: Similarity
messages: Belongs to the TrpF family.

1743168:A8O14 RS00245
gene id: 1743168:A8O14_RS00245
uniprot id: A0A191UC98
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1743168:A8O14 RS06655
gene id: 1743168:A8O14_RS06655
uniprot id: A0A191UFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1743168:A8O14 RS04635
gene id: 1743168:A8O14_RS04635
uniprot id: A0A191UES5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1743168:A8O14 RS00355
gene id: 1743168:A8O14_RS00355
uniprot id: A0A191UCE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1743168:A8O14 RS01360
gene id: 1743168:A8O14_RS01360
uniprot id: A0A191UD98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1743168:A8O14 RS00255
gene id: 1743168:A8O14_RS00255
uniprot id: A0A191UCP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1743168:A8O14 RS08245
gene id: 1743168:A8O14_RS08245
uniprot id: A0A191UGD6
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS00660
gene id: 1743168:A8O14_RS00660
uniprot id: A0A191UCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1743168:A8O14 RS04060
gene id: 1743168:A8O14_RS04060
uniprot id: A0A191UE99
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1743168:A8O14 RS03725
gene id: 1743168:A8O14_RS03725
uniprot id: A0A191UE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS11255
gene id: 1743168:A8O14_RS11255
uniprot id: A0A191UHX4
names: Similarity
messages: Belongs to the UPF0235 family.

1743168:A8O14 RS09110
gene id: 1743168:A8O14_RS09110
uniprot id: A0A191UGW6
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1743168:A8O14 RS03270
gene id: 1743168:A8O14_RS03270
uniprot id: A0A191UDR8
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1743168:A8O14 RS00010
gene id: 1743168:A8O14_RS00010
uniprot id: A0A191UCK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1743168:A8O14 RS09915
gene id: 1743168:A8O14_RS09915
uniprot id: A0A191UH68
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1743168:A8O14 RS05075
gene id: 1743168:A8O14_RS05075
uniprot id: A0A191UF46
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1743168:A8O14 RS10025
gene id: 1743168:A8O14_RS10025
uniprot id: A0A191UH88
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1743168:A8O14 RS10520
gene id: 1743168:A8O14_RS10520
uniprot id: A0A191UHH2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

1743168:A8O14 RS10645
gene id: 1743168:A8O14_RS10645
uniprot id: A0A191UHK5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1743168:A8O14 RS08345
gene id: 1743168:A8O14_RS08345
uniprot id: A0A191UGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Membrane
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

1743168:A8O14 RS04395
gene id: 1743168:A8O14_RS04395
uniprot id: A0A191UET4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS05200
gene id: 1743168:A8O14_RS05200
uniprot id: A0A191UF63
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1743168:A8O14 RS03685
gene id: 1743168:A8O14_RS03685
uniprot id: A0A191UEF5
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS04705
gene id: 1743168:A8O14_RS04705
uniprot id: A0A191UEX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1743168:A8O14 RS04610
gene id: 1743168:A8O14_RS04610
uniprot id: A0A191UEF7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1743168:A8O14 RS00585
gene id: 1743168:A8O14_RS00585
uniprot id: A0A191UIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1743168:A8O14 RS10845
gene id: 1743168:A8O14_RS10845
uniprot id: A0A191UHQ9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1743168:A8O14 RS03540
gene id: 1743168:A8O14_RS03540
uniprot id: A0A191UE21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS11345
gene id: 1743168:A8O14_RS11345
uniprot id: A0A191UHZ6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1743168:A8O14 RS05750
gene id: 1743168:A8O14_RS05750
uniprot id: A0A191UFE8
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS08195
gene id: 1743168:A8O14_RS08195
uniprot id: A0A191UGM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1743168:A8O14 RS07600
gene id: 1743168:A8O14_RS07600
uniprot id: A0A191UGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS05335
gene id: 1743168:A8O14_RS05335
uniprot id: A0A191UF79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1743168:A8O14 RS03280
gene id: 1743168:A8O14_RS03280
uniprot id: A0A191UE85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1743168:A8O14 RS01290
gene id: 1743168:A8O14_RS01290
uniprot id: A0A191UCV6
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1743168:A8O14 RS02200
gene id: 1743168:A8O14_RS02200
uniprot id: A0A191UD85
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1743168:A8O14 RS08790
gene id: 1743168:A8O14_RS08790
uniprot id: A0A191UGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1743168:A8O14 RS10990
gene id: 1743168:A8O14_RS10990
uniprot id: A0A191UI37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1743168:A8O14 RS04040
gene id: 1743168:A8O14_RS04040
uniprot id: A0A191UEL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1743168:A8O14 RS05445
gene id: 1743168:A8O14_RS05445
uniprot id: A0A191UIK8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1743168:A8O14 RS05210
gene id: 1743168:A8O14_RS05210
uniprot id: A0A191UF24
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1743168:A8O14 RS01930
gene id: 1743168:A8O14_RS01930
uniprot id: A0A191UD34
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1743168:A8O14 RS03680
gene id: 1743168:A8O14_RS03680
uniprot id: A0A191UEF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS02825
gene id: 1743168:A8O14_RS02825
uniprot id: A0A191UDI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1743168:A8O14 RS08980
gene id: 1743168:A8O14_RS08980
uniprot id: A0A191UGS7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1743168:A8O14 RS09855
gene id: 1743168:A8O14_RS09855
uniprot id: A0A191UHI8
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1743168:A8O14 RS03940
gene id: 1743168:A8O14_RS03940
uniprot id: A0A191UEE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS07790
gene id: 1743168:A8O14_RS07790
uniprot id: A0A191UG41
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1743168:A8O14 RS08880
gene id: 1743168:A8O14_RS08880
uniprot id: A0A191UH13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS05540
gene id: 1743168:A8O14_RS05540
uniprot id: A0A191UFA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1743168:A8O14 RS00595
gene id: 1743168:A8O14_RS00595
uniprot id: A0A191UCW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1743168:A8O14 RS11210
gene id: 1743168:A8O14_RS11210
uniprot id: A0A191UHW3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1743168:A8O14 RS02830
gene id: 1743168:A8O14_RS02830
uniprot id: A0A191UDM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1743168:A8O14 RS05715
gene id: 1743168:A8O14_RS05715
uniprot id: A0A191UFD8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1743168:A8O14 RS00785
gene id: 1743168:A8O14_RS00785
uniprot id: A0A191UCL7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1743168:A8O14 RS04320
gene id: 1743168:A8O14_RS04320
uniprot id: A0A191UEL5
names: Similarity
messages: Belongs to the citrate synthase family.

1743168:A8O14 RS02800
gene id: 1743168:A8O14_RS02800
uniprot id: A0A191UDM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1743168:A8O14 RS02000
gene id: 1743168:A8O14_RS02000
uniprot id: A0A191UDK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1743168:A8O14 RS09815
gene id: 1743168:A8O14_RS09815
uniprot id: A0A191UH52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1743168:A8O14 RS06735
gene id: 1743168:A8O14_RS06735
uniprot id: A0A191UFJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1743168:A8O14 RS03430
gene id: 1743168:A8O14_RS03430
uniprot id: A0A191UE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS10860
gene id: 1743168:A8O14_RS10860
uniprot id: A0A191UI13
names: Similarity
messages: Belongs to the peptidase S41A family.

1743168:A8O14 RS00420
gene id: 1743168:A8O14_RS00420
uniprot id: A0A191UCK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1743168:A8O14 RS08490
gene id: 1743168:A8O14_RS08490
uniprot id: A0A191UIH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1743168:A8O14 RS04540
gene id: 1743168:A8O14_RS04540
uniprot id: A0A191UEW0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS11175
gene id: 1743168:A8O14_RS11175
uniprot id: A0A191UI60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1743168:A8O14 RS01205
gene id: 1743168:A8O14_RS01205
uniprot id: A0A191UCU2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1743168:A8O14 RS06170
gene id: 1743168:A8O14_RS06170
uniprot id: A0A191UFH1
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS06990
gene id: 1743168:A8O14_RS06990
uniprot id: A0A191UFV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1743168:A8O14 RS03125
gene id: 1743168:A8O14_RS03125
uniprot id: A0A191UE59
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1743168:A8O14 RS00095
gene id: 1743168:A8O14_RS00095
uniprot id: A0A191UCN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1743168:A8O14 RS07750
gene id: 1743168:A8O14_RS07750
uniprot id: A0A191UGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1743168:A8O14 RS00230
gene id: 1743168:A8O14_RS00230
uniprot id: A0A191UCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1743168:A8O14 RS05705
gene id: 1743168:A8O14_RS05705
uniprot id: A0A191UEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1743168:A8O14 RS10630
gene id: 1743168:A8O14_RS10630
uniprot id: A0A191UHX8
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS09580
gene id: 1743168:A8O14_RS09580
uniprot id: A0A191UHC5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1743168:A8O14 RS08650
gene id: 1743168:A8O14_RS08650
uniprot id: A0A191UGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS01610
gene id: 1743168:A8O14_RS01610
uniprot id: A0A191UCY0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1743168:A8O14 RS07615
gene id: 1743168:A8O14_RS07615
uniprot id: A0A191UG04
names: Similarity
messages: Belongs to the peptidase U62 family.

1743168:A8O14 RS09380
gene id: 1743168:A8O14_RS09380
uniprot id: A0A191UH08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1743168:A8O14 RS07735
gene id: 1743168:A8O14_RS07735
uniprot id: A0A191UG23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1743168:A8O14 RS06535
gene id: 1743168:A8O14_RS06535
uniprot id: A0A191UFF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS05565
gene id: 1743168:A8O14_RS05565
uniprot id: A0A191UEX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1743168:A8O14 RS00125
gene id: 1743168:A8O14_RS00125
uniprot id: A0A191UCG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS00440
gene id: 1743168:A8O14_RS00440
uniprot id: A0A191UCT9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1743168:A8O14 RS03435
gene id: 1743168:A8O14_RS03435
uniprot id: A0A191UEB5
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

1743168:A8O14 RS03855
gene id: 1743168:A8O14_RS03855
uniprot id: A0A191UE67
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1743168:A8O14 RS10495
gene id: 1743168:A8O14_RS10495
uniprot id: A0A191UHU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1743168:A8O14 RS03945
gene id: 1743168:A8O14_RS03945
uniprot id: A0A191UE28
names: Similarity
messages: Belongs to the YfgM family.

1743168:A8O14 RS09345
gene id: 1743168:A8O14_RS09345
uniprot id: A0A191UH01
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1743168:A8O14 RS10420
gene id: 1743168:A8O14_RS10420
uniprot id: A0A191UHR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1743168:A8O14 RS08795
gene id: 1743168:A8O14_RS08795
uniprot id: A0A191UH03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1743168:A8O14 RS10720
gene id: 1743168:A8O14_RS10720
uniprot id: A0A191UHX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1743168:A8O14 RS07640
gene id: 1743168:A8O14_RS07640
uniprot id: A0A191UG72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1743168:A8O14 RS11380
gene id: 1743168:A8O14_RS11380
uniprot id: A0A191UI92
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1743168:A8O14 RS09020
gene id: 1743168:A8O14_RS09020
uniprot id: A0A191UH29
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS04145
gene id: 1743168:A8O14_RS04145
uniprot id: A0A191UE63
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1743168:A8O14 RS00815
gene id: 1743168:A8O14_RS00815
uniprot id: A0A191UCJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1743168:A8O14 RS07170
gene id: 1743168:A8O14_RS07170
uniprot id: A0A191UFY7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1743168:A8O14 RS02040
gene id: 1743168:A8O14_RS02040
uniprot id: A0A191UD91
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1743168:A8O14 RS09555
gene id: 1743168:A8O14_RS09555
uniprot id: A0A191UH43
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1743168:A8O14 RS00870
gene id: 1743168:A8O14_RS00870
uniprot id: A0A191UI23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1743168:A8O14 RS09920
gene id: 1743168:A8O14_RS09920
uniprot id: A0A191UHJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1743168:A8O14 RS08740
gene id: 1743168:A8O14_RS08740
uniprot id: A0A191UGN1
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS10700
gene id: 1743168:A8O14_RS10700
uniprot id: A0A191UHL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1743168:A8O14 RS02375
gene id: 1743168:A8O14_RS02375
uniprot id: A0A191UDF1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1743168:A8O14 RS02530
gene id: 1743168:A8O14_RS02530
uniprot id: A0A191UDH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS02095
gene id: 1743168:A8O14_RS02095
uniprot id: A0A191UDM3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1743168:A8O14 RS08775
gene id: 1743168:A8O14_RS08775
uniprot id: A0A191UGX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1743168:A8O14 RS03870
gene id: 1743168:A8O14_RS03870
uniprot id: A0A191UEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

1743168:A8O14 RS09535
gene id: 1743168:A8O14_RS09535
uniprot id: A0A191UGZ5
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1743168:A8O14 RS08010
gene id: 1743168:A8O14_RS08010
uniprot id: A0A191UGH5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1743168:A8O14 RS07020
gene id: 1743168:A8O14_RS07020
uniprot id: A0A191UG12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1743168:A8O14 RS00065
gene id: 1743168:A8O14_RS00065
uniprot id: A0A191UCL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1743168:A8O14 RS01615
gene id: 1743168:A8O14_RS01615
uniprot id: A0A191UD12
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS08125
gene id: 1743168:A8O14_RS08125
uniprot id: A0A191UGA5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1743168:A8O14 RS04155
gene id: 1743168:A8O14_RS04155
uniprot id: A0A191UEN2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1743168:A8O14 RS10595
gene id: 1743168:A8O14_RS10595
uniprot id: A0A191UHJ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1743168:A8O14 RS00865
gene id: 1743168:A8O14_RS00865
uniprot id: A0A191UI14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1743168:A8O14 RS01540
gene id: 1743168:A8O14_RS01540
uniprot id: A0A191UDC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1743168:A8O14 RS03740
gene id: 1743168:A8O14_RS03740
uniprot id: A0A191UEB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS02885
gene id: 1743168:A8O14_RS02885
uniprot id: A0A191UE12
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1743168:A8O14 RS00045
gene id: 1743168:A8O14_RS00045
uniprot id: A0A191UCM4
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS08255
gene id: 1743168:A8O14_RS08255
uniprot id: A0A191UGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS07025
gene id: 1743168:A8O14_RS07025
uniprot id: A0A191UFW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS06835
gene id: 1743168:A8O14_RS06835
uniprot id: A0A191UFL2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1743168:A8O14 RS05410
gene id: 1743168:A8O14_RS05410
uniprot id: A0A191UF95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1743168:A8O14 RS07610
gene id: 1743168:A8O14_RS07610
uniprot id: A0A191UG70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1743168:A8O14 RS05385
gene id: 1743168:A8O14_RS05385
uniprot id: A0A191UIJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS09475
gene id: 1743168:A8O14_RS09475
uniprot id: A0A191UH26
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1743168:A8O14 RS08950
gene id: 1743168:A8O14_RS08950
uniprot id: A0A191UGQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1743168:A8O14 RS00300
gene id: 1743168:A8O14_RS00300
uniprot id: A0A191UCD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1743168:A8O14 RS07165
gene id: 1743168:A8O14_RS07165
uniprot id: A0A191UG35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1743168:A8O14 RS08760
gene id: 1743168:A8O14_RS08760
uniprot id: A0A191UGM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1743168:A8O14 RS02145
gene id: 1743168:A8O14_RS02145
uniprot id: A0A191UDH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1743168:A8O14 RS00525
gene id: 1743168:A8O14_RS00525
uniprot id: A0A191UCE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS04245
gene id: 1743168:A8O14_RS04245
uniprot id: A0A191UE86
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1743168:A8O14 RS02220
gene id: 1743168:A8O14_RS02220
uniprot id: A0A191UDI6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1743168:A8O14 RS03250
gene id: 1743168:A8O14_RS03250
uniprot id: A0A191UE81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1743168:A8O14 RS01710
gene id: 1743168:A8O14_RS01710
uniprot id: A0A191UDF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS09070
gene id: 1743168:A8O14_RS09070
uniprot id: A0A191UGT9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1743168:A8O14 RS05430
gene id: 1743168:A8O14_RS05430
uniprot id: A0A191UF91
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1743168:A8O14 RS00165
gene id: 1743168:A8O14_RS00165
uniprot id: A0A191UCP4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1743168:A8O14 RS10930
gene id: 1743168:A8O14_RS10930
uniprot id: A0A191UHR3
names: Similarity
messages: Belongs to the UPF0250 family.

1743168:A8O14 RS02545
gene id: 1743168:A8O14_RS02545
uniprot id: A0A191UDV8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1743168:A8O14 RS03960
gene id: 1743168:A8O14_RS03960
uniprot id: A0A191UEJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1743168:A8O14 RS11270
gene id: 1743168:A8O14_RS11270
uniprot id: A0A191UHX0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1743168:A8O14 RS01845
gene id: 1743168:A8O14_RS01845
uniprot id: A0A191UD20
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS01585
gene id: 1743168:A8O14_RS01585
uniprot id: A0A191UDC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1743168:A8O14 RS00680
gene id: 1743168:A8O14_RS00680
uniprot id: A0A191UCH9
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1743168:A8O14 RS06080
gene id: 1743168:A8O14_RS06080
uniprot id: A0A191UFG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1743168:A8O14 RS03890
gene id: 1743168:A8O14_RS03890
uniprot id: A0A191UE72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1743168:A8O14 RS02295
gene id: 1743168:A8O14_RS02295
uniprot id: A0A191UDJ9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1743168:A8O14 RS06520
gene id: 1743168:A8O14_RS06520
uniprot id: A0A191UFS3
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS11075
gene id: 1743168:A8O14_RS11075
uniprot id: A0A191UHT4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1743168:A8O14 RS11440
gene id: 1743168:A8O14_RS11440
uniprot id: A0A191UI10
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1743168:A8O14 RS07995
gene id: 1743168:A8O14_RS07995
uniprot id: A0A191UG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1743168:A8O14 RS01270
gene id: 1743168:A8O14_RS01270
uniprot id: A0A191UD71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1743168:A8O14 RS03610
gene id: 1743168:A8O14_RS03610
uniprot id: A0A191UDX8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1743168:A8O14 RS02140
gene id: 1743168:A8O14_RS02140
uniprot id: A0A191UDN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

1743168:A8O14 RS02060
gene id: 1743168:A8O14_RS02060
uniprot id: A0A191UD60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1743168:A8O14 RS01980
gene id: 1743168:A8O14_RS01980
uniprot id: A0A191UDD5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1743168:A8O14 RS07980
gene id: 1743168:A8O14_RS07980
uniprot id: A0A191UGH6
names: Similarity
messages: Belongs to the PrpD family.

1743168:A8O14 RS08595
gene id: 1743168:A8O14_RS08595
uniprot id: A0A191UGN0
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1743168:A8O14 RS09100
gene id: 1743168:A8O14_RS09100
uniprot id: A0A191UH50
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1743168:A8O14 RS09500
gene id: 1743168:A8O14_RS09500
uniprot id: A0A191UH34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1743168:A8O14 RS07690
gene id: 1743168:A8O14_RS07690
uniprot id: A0A191UGC0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1743168:A8O14 RS00920
gene id: 1743168:A8O14_RS00920
uniprot id: A0A191UD21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1743168:A8O14 RS00110
gene id: 1743168:A8O14_RS00110
uniprot id: A0A191UCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1743168:A8O14 RS08520
gene id: 1743168:A8O14_RS08520
uniprot id: A0A191UGI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1743168:A8O14 RS05700
gene id: 1743168:A8O14_RS05700
uniprot id: A0A191UFA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1743168:A8O14 RS04365
gene id: 1743168:A8O14_RS04365
uniprot id: A0A191UES8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1743168:A8O14 RS07970
gene id: 1743168:A8O14_RS07970
uniprot id: A0A191UG74
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1743168:A8O14 RS10040
gene id: 1743168:A8O14_RS10040
uniprot id: A0A191UHC2
names: Similarity
messages: Belongs to the pyruvate kinase family.

1743168:A8O14 RS06940
gene id: 1743168:A8O14_RS06940
uniprot id: A0A191UIN7
names: Similarity
messages: Belongs to the YjdM family.

1743168:A8O14 RS01790
gene id: 1743168:A8O14_RS01790
uniprot id: A0A191UD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS05630
gene id: 1743168:A8O14_RS05630
uniprot id: A0A191UEZ9
names: Similarity
messages: Belongs to the IlvD/Edd family.

1743168:A8O14 RS00630
gene id: 1743168:A8O14_RS00630
uniprot id: A0A191UCG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1743168:A8O14 RS09120
gene id: 1743168:A8O14_RS09120
uniprot id: A0A191UGU6
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1743168:A8O14 RS02850
gene id: 1743168:A8O14_RS02850
uniprot id: A0A191UDJ2
names: Similarity
messages: Belongs to the skp family.

1743168:A8O14 RS02470
gene id: 1743168:A8O14_RS02470
uniprot id: A0A191UDM7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1743168:A8O14 RS07265
gene id: 1743168:A8O14_RS07265
uniprot id: A0A191UFU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1743168:A8O14 RS09960
gene id: 1743168:A8O14_RS09960
uniprot id: A0A191UIL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS05030
gene id: 1743168:A8O14_RS05030
uniprot id: A0A191UER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1743168:A8O14 RS07195
gene id: 1743168:A8O14_RS07195
uniprot id: A0A191UG38
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1743168:A8O14 RS01015
gene id: 1743168:A8O14_RS01015
uniprot id: A0A191UD28
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS10105
gene id: 1743168:A8O14_RS10105
uniprot id: A0A191UHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1743168:A8O14 RS00270
gene id: 1743168:A8O14_RS00270
uniprot id: A0A191UCA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1743168:A8O14 RS07740
gene id: 1743168:A8O14_RS07740
uniprot id: A0A191UG30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1743168:A8O14 RS06675
gene id: 1743168:A8O14_RS06675
uniprot id: A0A191UFQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1743168:A8O14 RS10690
gene id: 1743168:A8O14_RS10690
uniprot id: A0A191UHW4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1743168:A8O14 RS11165
gene id: 1743168:A8O14_RS11165
uniprot id: A0A191UI66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1743168:A8O14 RS03615
gene id: 1743168:A8O14_RS03615
uniprot id: A0A191UE29
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS07965
gene id: 1743168:A8O14_RS07965
uniprot id: A0A191UGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS08035
gene id: 1743168:A8O14_RS08035
uniprot id: A0A191UGH9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1743168:A8O14 RS00055
gene id: 1743168:A8O14_RS00055
uniprot id: A0A191UC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS10830
gene id: 1743168:A8O14_RS10830
uniprot id: A0A191UHP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1743168:A8O14 RS04755
gene id: 1743168:A8O14_RS04755
uniprot id: A0A191UEM0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1743168:A8O14 RS01080
gene id: 1743168:A8O14_RS01080
uniprot id: A0A191UCX4
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1743168:A8O14 RS01280
gene id: 1743168:A8O14_RS01280
uniprot id: A0A191UD08
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1743168:A8O14 RS08830
gene id: 1743168:A8O14_RS08830
uniprot id: A0A191UGR8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1743168:A8O14 RS01455
gene id: 1743168:A8O14_RS01455
uniprot id: A0A191UDB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1743168:A8O14 RS00400
gene id: 1743168:A8O14_RS00400
uniprot id: A0A191UCD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1743168:A8O14 RS04885
gene id: 1743168:A8O14_RS04885
uniprot id: A0A191UIJ7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1743168:A8O14 RS08505
gene id: 1743168:A8O14_RS08505
uniprot id: A0A191UGT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS08285
gene id: 1743168:A8O14_RS08285
uniprot id: A0A191UGM5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1743168:A8O14 RS01210
gene id: 1743168:A8O14_RS01210
uniprot id: A0A191UD61
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1743168:A8O14 RS09910
gene id: 1743168:A8O14_RS09910
uniprot id: A0A191UH72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1743168:A8O14 RS04480
gene id: 1743168:A8O14_RS04480
uniprot id: A0A191UEV3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1743168:A8O14 RS09965
gene id: 1743168:A8O14_RS09965
uniprot id: A0A191UHA8
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1743168:A8O14 RS01225
gene id: 1743168:A8O14_RS01225
uniprot id: A0A191UCS0
names: Similarity
messages: Belongs to the transketolase family.

1743168:A8O14 RS01310
gene id: 1743168:A8O14_RS01310
uniprot id: A0A191UD14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1743168:A8O14 RS10900
gene id: 1743168:A8O14_RS10900
uniprot id: A0A191UHQ1
names: Similarity
messages: Belongs to the P(II) protein family.

1743168:A8O14 RS01240
gene id: 1743168:A8O14_RS01240
uniprot id: A0A191UD66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1743168:A8O14 RS10430
gene id: 1743168:A8O14_RS10430
uniprot id: A0A191UHG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

1743168:A8O14 RS07680
gene id: 1743168:A8O14_RS07680
uniprot id: A0A191UG14
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1743168:A8O14 RS07330
gene id: 1743168:A8O14_RS07330
uniprot id: A0A191UG57
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1743168:A8O14 RS04325
gene id: 1743168:A8O14_RS04325
uniprot id: A0A191UEA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1743168:A8O14 RS00845
gene id: 1743168:A8O14_RS00845
uniprot id: A0A191UCM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS02075
gene id: 1743168:A8O14_RS02075
uniprot id: A0A191UDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1743168:A8O14 RS09545
gene id: 1743168:A8O14_RS09545
uniprot id: A0A191UHC8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1743168:A8O14 RS04670
gene id: 1743168:A8O14_RS04670
uniprot id: A0A191UEG7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1743168:A8O14 RS04760
gene id: 1743168:A8O14_RS04760
uniprot id: A0A191UEY5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1743168:A8O14 RS02055
gene id: 1743168:A8O14_RS02055
uniprot id: A0A191UDF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1743168:A8O14 RS02260
gene id: 1743168:A8O14_RS02260
uniprot id: A0A191UDQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1743168:A8O14 RS01345
gene id: 1743168:A8O14_RS01345
uniprot id: A0A191UCT8
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

1743168:A8O14 RS01140
gene id: 1743168:A8O14_RS01140
uniprot id: A0A191UCQ5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1743168:A8O14 RS06445
gene id: 1743168:A8O14_RS06445
uniprot id: A0A191UFR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1743168:A8O14 RS06465
gene id: 1743168:A8O14_RS06465
uniprot id: A0A191UIC1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1743168:A8O14 RS08450
gene id: 1743168:A8O14_RS08450
uniprot id: A0A191UGR0
names: Function
names: Similarity
messages: Belongs to the AcsF family.
messages: Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).

1743168:A8O14 RS03180
gene id: 1743168:A8O14_RS03180
uniprot id: A0A191UE69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1743168:A8O14 RS01355
gene id: 1743168:A8O14_RS01355
uniprot id: A0A191UD86
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1743168:A8O14 RS03720
gene id: 1743168:A8O14_RS03720
uniprot id: A0A191UDZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS00945
gene id: 1743168:A8O14_RS00945
uniprot id: A0A191UD26
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1743168:A8O14 RS01065
gene id: 1743168:A8O14_RS01065
uniprot id: A0A191UCR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1743168:A8O14 RS00885
gene id: 1743168:A8O14_RS00885
uniprot id: A0A191UCN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1743168:A8O14 RS06485
gene id: 1743168:A8O14_RS06485
uniprot id: A0A191UFR8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1743168:A8O14 RS10050
gene id: 1743168:A8O14_RS10050
uniprot id: A0A191UH96
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1743168:A8O14 RS10020
gene id: 1743168:A8O14_RS10020
uniprot id: A0A191UH87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1743168:A8O14 RS02020
gene id: 1743168:A8O14_RS02020
uniprot id: A0A191UDK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1743168:A8O14 RS08305
gene id: 1743168:A8O14_RS08305
uniprot id: A0A191UGP9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1743168:A8O14 RS02280
gene id: 1743168:A8O14_RS02280
uniprot id: A0A191UDD7
names: Cofactor
messages: Can also use Mn(2+) ion.

1743168:A8O14 RS01565
gene id: 1743168:A8O14_RS01565
uniprot id: A0A191UDD3
names: Similarity
messages: Belongs to the UPF0234 family.

1743168:A8O14 RS07085
gene id: 1743168:A8O14_RS07085
uniprot id: A0A191UFX1
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS04370
gene id: 1743168:A8O14_RS04370
uniprot id: A0A191UEM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1743168:A8O14 RS04270
gene id: 1743168:A8O14_RS04270
uniprot id: A0A191UEK6
names: Similarity
messages: Belongs to the UPF0246 family.

1743168:A8O14 RS04440
gene id: 1743168:A8O14_RS04440
uniprot id: A0A191UEH0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1743168:A8O14 RS01445
gene id: 1743168:A8O14_RS01445
uniprot id: A0A191UIE2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1743168:A8O14 RS11235
gene id: 1743168:A8O14_RS11235
uniprot id: A0A191UI70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1743168:A8O14 RS04925
gene id: 1743168:A8O14_RS04925
uniprot id: A0A191UEX5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1743168:A8O14 RS09395
gene id: 1743168:A8O14_RS09395
uniprot id: A0A191UGY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1743168:A8O14 RS10570
gene id: 1743168:A8O14_RS10570
uniprot id: A0A191UHI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS01970
gene id: 1743168:A8O14_RS01970
uniprot id: A0A191UDJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1743168:A8O14 RS08020
gene id: 1743168:A8O14_RS08020
uniprot id: A0A191UG85
names: PTM
messages: Binds 1 heme group per subunit.

1743168:A8O14 RS05725
gene id: 1743168:A8O14_RS05725
uniprot id: A0A191UFA9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1743168:A8O14 RS01775
gene id: 1743168:A8O14_RS01775
uniprot id: A0A191UI42
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS01400
gene id: 1743168:A8O14_RS01400
uniprot id: A0A191UI31
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS04450
gene id: 1743168:A8O14_RS04450
uniprot id: A0A191UET3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1743168:A8O14 RS11460
gene id: 1743168:A8O14_RS11460
uniprot id: A0A191UHZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1743168:A8O14 RS02085
gene id: 1743168:A8O14_RS02085
uniprot id: A0A191UD65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1743168:A8O14 RS08400
gene id: 1743168:A8O14_RS08400
uniprot id: A0A191UGP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1743168:A8O14 RS00120
gene id: 1743168:A8O14_RS00120
uniprot id: A0A191UCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1743168:A8O14 RS01480
gene id: 1743168:A8O14_RS01480
uniprot id: A0A191UDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1743168:A8O14 RS04750
gene id: 1743168:A8O14_RS04750
uniprot id: A0A191UEI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1743168:A8O14 RS03665
gene id: 1743168:A8O14_RS03665
uniprot id: A0A191UDY5
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1743168:A8O14 RS07315
gene id: 1743168:A8O14_RS07315
uniprot id: A0A191UG11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1743168:A8O14 RS07060
gene id: 1743168:A8O14_RS07060
uniprot id: A0A191UFQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1743168:A8O14 RS01385
gene id: 1743168:A8O14_RS01385
uniprot id: A0A191UD90
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS02070
gene id: 1743168:A8O14_RS02070
uniprot id: A0A191UDL8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1743168:A8O14 RS02520
gene id: 1743168:A8O14_RS02520
uniprot id: A0A191UDN6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1743168:A8O14 RS03970
gene id: 1743168:A8O14_RS03970
uniprot id: A0A191UEE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1743168:A8O14 RS04505
gene id: 1743168:A8O14_RS04505
uniprot id: A0A191UEU3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1743168:A8O14 RS06435
gene id: 1743168:A8O14_RS06435
uniprot id: A0A191UIL8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1743168:A8O14 RS09970
gene id: 1743168:A8O14_RS09970
uniprot id: A0A191UH81
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1743168:A8O14 RS08665
gene id: 1743168:A8O14_RS08665
uniprot id: A0A191UGU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1743168:A8O14 RS08070
gene id: 1743168:A8O14_RS08070
uniprot id: A0A191UG94
names: Similarity
messages: Belongs to the universal stress protein A family.

1743168:A8O14 RS00875
gene id: 1743168:A8O14_RS00875
uniprot id: A0A191UCT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1743168:A8O14 RS09780
gene id: 1743168:A8O14_RS09780
uniprot id: A0A191UHF7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1743168:A8O14 RS09465
gene id: 1743168:A8O14_RS09465
uniprot id: A0A191UHB4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1743168:A8O14 RS07230
gene id: 1743168:A8O14_RS07230
uniprot id: A0A191UG43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1743168:A8O14 RS07770
gene id: 1743168:A8O14_RS07770
uniprot id: A0A191UGD4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1743168:A8O14 RS11285
gene id: 1743168:A8O14_RS11285
uniprot id: A0A191UHY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1743168:A8O14 RS01135
gene id: 1743168:A8O14_RS01135
uniprot id: A0A191UCY4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1743168:A8O14 RS02745
gene id: 1743168:A8O14_RS02745
uniprot id: A0A191UDH2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1743168:A8O14 RS03170
gene id: 1743168:A8O14_RS03170
uniprot id: A0A191UDU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

1743168:A8O14 RS00365
gene id: 1743168:A8O14_RS00365
uniprot id: A0A191UCS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1743168:A8O14 RS11215
gene id: 1743168:A8O14_RS11215
uniprot id: A0A191UHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1743168:A8O14 RS00975
gene id: 1743168:A8O14_RS00975
uniprot id: A0A191UCV5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1743168:A8O14 RS02015
gene id: 1743168:A8O14_RS02015
uniprot id: A0A191UD82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1743168:A8O14 RS03450
gene id: 1743168:A8O14_RS03450
uniprot id: A0A191UDV3
names: Similarity
messages: Belongs to the HIBADH-related family.

1743168:A8O14 RS10455
gene id: 1743168:A8O14_RS10455
uniprot id: A0A191UHK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1743168:A8O14 RS06300
gene id: 1743168:A8O14_RS06300
uniprot id: A0A191UFP0
names: Similarity
messages: Belongs to the YciI family.

1743168:A8O14 RS05070
gene id: 1743168:A8O14_RS05070
uniprot id: A0A191UF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1743168:A8O14 RS04930
gene id: 1743168:A8O14_RS04930
uniprot id: A0A191UEL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1743168:A8O14 RS10500
gene id: 1743168:A8O14_RS10500
uniprot id: A0A191UHT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1743168:A8O14 RS07775
gene id: 1743168:A8O14_RS07775
uniprot id: A0A191UGD3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS05390
gene id: 1743168:A8O14_RS05390
uniprot id: A0A191UEU2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1743168:A8O14 RS02435
gene id: 1743168:A8O14_RS02435
uniprot id: A0A191UDT2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1743168:A8O14 RS05730
gene id: 1743168:A8O14_RS05730
uniprot id: A0A191UF01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS05020
gene id: 1743168:A8O14_RS05020
uniprot id: A0A191UEY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1743168:A8O14 RS10485
gene id: 1743168:A8O14_RS10485
uniprot id: A0A191UHH1
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1743168:A8O14 RS02105
gene id: 1743168:A8O14_RS02105
uniprot id: A0A191UDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1743168:A8O14 RS01485
gene id: 1743168:A8O14_RS01485
uniprot id: A0A191UDB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1743168:A8O14 RS01415
gene id: 1743168:A8O14_RS01415
uniprot id: A0A191UD95
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1743168:A8O14 RS06515
gene id: 1743168:A8O14_RS06515
uniprot id: A0A191UFF2
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS02855
gene id: 1743168:A8O14_RS02855
uniprot id: A0A191UDN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1743168:A8O14 RS09925
gene id: 1743168:A8O14_RS09925
uniprot id: A0A191UHI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1743168:A8O14 RS09130
gene id: 1743168:A8O14_RS09130
uniprot id: A0A191UH42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1743168:A8O14 RS07190
gene id: 1743168:A8O14_RS07190
uniprot id: A0A191UG28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1743168:A8O14 RS00160
gene id: 1743168:A8O14_RS00160
uniprot id: A0A191UI01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1743168:A8O14 RS04590
gene id: 1743168:A8O14_RS04590
uniprot id: A0A191UEJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1743168:A8O14 RS04220
gene id: 1743168:A8O14_RS04220
uniprot id: A0A191UE80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1743168:A8O14 RS02010
gene id: 1743168:A8O14_RS02010
uniprot id: A0A191UD49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1743168:A8O14 RS04915
gene id: 1743168:A8O14_RS04915
uniprot id: A0A191UF23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS02845
gene id: 1743168:A8O14_RS02845
uniprot id: A0A191UDU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1743168:A8O14 RS10725
gene id: 1743168:A8O14_RS10725
uniprot id: A0A191UHP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1743168:A8O14 RS02335
gene id: 1743168:A8O14_RS02335
uniprot id: A0A191UDK4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1743168:A8O14 RS09675
gene id: 1743168:A8O14_RS09675
uniprot id: A0A191UH18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1743168:A8O14 RS04765
gene id: 1743168:A8O14_RS04765
uniprot id: A0A191UF02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1743168:A8O14 RS00315
gene id: 1743168:A8O14_RS00315
uniprot id: A0A191UCR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1743168:A8O14 RS03910
gene id: 1743168:A8O14_RS03910
uniprot id: A0A191UE23
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1743168:A8O14 RS08005
gene id: 1743168:A8O14_RS08005
uniprot id: A0A191UGI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1743168:A8O14 RS01920
gene id: 1743168:A8O14_RS01920
uniprot id: A0A191UDJ1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1743168:A8O14 RS11665
gene id: 1743168:A8O14_RS11665
uniprot id: A0A191UHT8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1743168:A8O14 RS01285
gene id: 1743168:A8O14_RS01285
uniprot id: A0A191UCT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1743168:A8O14 RS02030
gene id: 1743168:A8O14_RS02030
uniprot id: A0A191UDE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1743168:A8O14 RS04860
gene id: 1743168:A8O14_RS04860
uniprot id: A0A191UEK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1743168:A8O14 RS02790
gene id: 1743168:A8O14_RS02790
uniprot id: A0A191UDT0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1743168:A8O14 RS10625
gene id: 1743168:A8O14_RS10625
uniprot id: A0A191UHK7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1743168:A8O14 RS08145
gene id: 1743168:A8O14_RS08145
uniprot id: A0A191UGF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1743168:A8O14 RS07180
gene id: 1743168:A8O14_RS07180
uniprot id: A0A191UFS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1743168:A8O14 RS03675
gene id: 1743168:A8O14_RS03675
uniprot id: A0A191UE39
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1743168:A8O14 RS11200
gene id: 1743168:A8O14_RS11200
uniprot id: A0A191UIM9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1743168:A8O14 RS00250
gene id: 1743168:A8O14_RS00250
uniprot id: A0A191UCC2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1743168:A8O14 RS02820
gene id: 1743168:A8O14_RS02820
uniprot id: A0A191UDT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1743168:A8O14 RS04340
gene id: 1743168:A8O14_RS04340
uniprot id: A0A191UES2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1743168:A8O14 RS03565
gene id: 1743168:A8O14_RS03565
uniprot id: A0A191UI55
names: Subcellular Location Annotation
messages: Membrane

1743168:A8O14 RS09850
gene id: 1743168:A8O14_RS09850
uniprot id: A0A191UH61
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1743168:A8O14 RS10735
gene id: 1743168:A8O14_RS10735
uniprot id: A0A191UHN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1743168:A8O14 RS07340
gene id: 1743168:A8O14_RS07340
uniprot id: A0A191UG17
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1743168:A8O14 RS04745
gene id: 1743168:A8O14_RS04745
uniprot id: A0A191UEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1743168:A8O14 RS04125
gene id: 1743168:A8O14_RS04125
uniprot id: A0A191UEB1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1743168:A8O14 RS03140
gene id: 1743168:A8O14_RS03140
uniprot id: A0A191UDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1743168:A8O14 RS04485
gene id: 1743168:A8O14_RS04485
uniprot id: A0A191UEP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.