172713:B4V02 RS17770
gene id: 172713:B4V02_RS17770
uniprot id: A0A222WQZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS21245
gene id: 172713:B4V02_RS21245
uniprot id: A0A222WTJ5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

172713:B4V02 RS22885
gene id: 172713:B4V02_RS22885
uniprot id: A0A222WS41
names: Similarity
messages: Belongs to the UPF0045 family.

172713:B4V02 RS09960
gene id: 172713:B4V02_RS09960
uniprot id: A0A222WMG2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

172713:B4V02 RS07485
gene id: 172713:B4V02_RS07485
uniprot id: A0A222WL54
names: Similarity
messages: Belongs to the MoaD family.

172713:B4V02 RS02750
gene id: 172713:B4V02_RS02750
uniprot id: A0A222WI96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

172713:B4V02 RS06060
gene id: 172713:B4V02_RS06060
uniprot id: A0A222WKF6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

172713:B4V02 RS22460
gene id: 172713:B4V02_RS22460
uniprot id: A0A222WRR1
names: Similarity
messages: Belongs to the RutC family.

172713:B4V02 RS10050
gene id: 172713:B4V02_RS10050
uniprot id: A0A222WKI7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

172713:B4V02 RS11205
gene id: 172713:B4V02_RS11205
uniprot id: A0A222WMT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

172713:B4V02 RS02910
gene id: 172713:B4V02_RS02910
uniprot id: A0A222WI12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

172713:B4V02 RS04500
gene id: 172713:B4V02_RS04500
uniprot id: A0A222WVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

172713:B4V02 RS10115
gene id: 172713:B4V02_RS10115
uniprot id: A0A222WMP2
names: Similarity
messages: Belongs to the thymidine kinase family.

172713:B4V02 RS02260
gene id: 172713:B4V02_RS02260
uniprot id: A0A222WGX7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

172713:B4V02 RS13485
gene id: 172713:B4V02_RS13485
uniprot id: A0A222WNB7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

172713:B4V02 RS06170
gene id: 172713:B4V02_RS06170
uniprot id: A0A222WKJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

172713:B4V02 RS09955
gene id: 172713:B4V02_RS09955
uniprot id: A0A222WLU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

172713:B4V02 RS03010
gene id: 172713:B4V02_RS03010
uniprot id: A0A222WI32
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

172713:B4V02 RS15765
gene id: 172713:B4V02_RS15765
uniprot id: A0A222WQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

172713:B4V02 RS15415
gene id: 172713:B4V02_RS15415
uniprot id: A0A222WPZ9
names: Similarity
messages: Belongs to the UPF0102 family.

172713:B4V02 RS07165
gene id: 172713:B4V02_RS07165
uniprot id: A0A222WKJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS15025
gene id: 172713:B4V02_RS15025
uniprot id: A0A222WN60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

172713:B4V02 RS02950
gene id: 172713:B4V02_RS02950
uniprot id: A0A222WID3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

172713:B4V02 RS18095
gene id: 172713:B4V02_RS18095
uniprot id: A0A222WS08
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS14605
gene id: 172713:B4V02_RS14605
uniprot id: A0A222WMU8
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

172713:B4V02 RS16920
gene id: 172713:B4V02_RS16920
uniprot id: A0A222WR51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

172713:B4V02 RS14965
gene id: 172713:B4V02_RS14965
uniprot id: A0A222WPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

172713:B4V02 RS15160
gene id: 172713:B4V02_RS15160
uniprot id: A0A222WPG9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS17520
gene id: 172713:B4V02_RS17520
uniprot id: A0A222WRL6
names: Similarity
messages: Belongs to the glutamine synthetase family.

172713:B4V02 RS17795
gene id: 172713:B4V02_RS17795
uniprot id: A0A222WRW1
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS03625
gene id: 172713:B4V02_RS03625
uniprot id: A0A222WIP4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

172713:B4V02 RS17815
gene id: 172713:B4V02_RS17815
uniprot id: A0A222WQI6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

172713:B4V02 RS02245
gene id: 172713:B4V02_RS02245
uniprot id: A0A222WI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

172713:B4V02 RS17775
gene id: 172713:B4V02_RS17775
uniprot id: A0A222WPK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

172713:B4V02 RS15435
gene id: 172713:B4V02_RS15435
uniprot id: A0A222WPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

172713:B4V02 RS07160
gene id: 172713:B4V02_RS07160
uniprot id: A0A222WKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS18910
gene id: 172713:B4V02_RS18910
uniprot id: A0A222WRI6
names: Similarity
messages: Belongs to the AHA1 family.

172713:B4V02 RS07075
gene id: 172713:B4V02_RS07075
uniprot id: A0A222WKF2
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS04280
gene id: 172713:B4V02_RS04280
uniprot id: A0A222WIP0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

172713:B4V02 RS24510
gene id: 172713:B4V02_RS24510
uniprot id: A0A222WUZ6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

172713:B4V02 RS25050
gene id: 172713:B4V02_RS25050
uniprot id: A0A222WV90
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

172713:B4V02 RS09005
gene id: 172713:B4V02_RS09005
uniprot id: A0A222WTH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

172713:B4V02 RS24320
gene id: 172713:B4V02_RS24320
uniprot id: A0A222WSK5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

172713:B4V02 RS15120
gene id: 172713:B4V02_RS15120
uniprot id: A0A222WN53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

172713:B4V02 RS18835
gene id: 172713:B4V02_RS18835
uniprot id: A0A222WRH6
names: Similarity
messages: Belongs to the GbsR family.

172713:B4V02 RS03930
gene id: 172713:B4V02_RS03930
uniprot id: A0A222WIT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

172713:B4V02 RS10525
gene id: 172713:B4V02_RS10525
uniprot id: A0A222WM48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

172713:B4V02 RS24335
gene id: 172713:B4V02_RS24335
uniprot id: A0A222WUD8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

172713:B4V02 RS02935
gene id: 172713:B4V02_RS02935
uniprot id: A0A222WIZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

172713:B4V02 RS02305
gene id: 172713:B4V02_RS02305
uniprot id: A0A222WHL0
names: Subcellular Location Annotation
messages: Cytoplasm

172713:B4V02 RS00370
gene id: 172713:B4V02_RS00370
uniprot id: A0A222WFT0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

172713:B4V02 RS17765
gene id: 172713:B4V02_RS17765
uniprot id: A0A222WPF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

172713:B4V02 RS04465
gene id: 172713:B4V02_RS04465
uniprot id: A0A222WIE4
names: Similarity
messages: Belongs to the PspA/IM30 family.

172713:B4V02 RS02210
gene id: 172713:B4V02_RS02210
uniprot id: A0A222WGW8
names: Similarity
messages: Belongs to the bacterial flagellin family.

172713:B4V02 RS08780
gene id: 172713:B4V02_RS08780
uniprot id: A0A222WJV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

172713:B4V02 RS06030
gene id: 172713:B4V02_RS06030
uniprot id: A0A222WJX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

172713:B4V02 RS21400
gene id: 172713:B4V02_RS21400
uniprot id: A0A222WSW1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

172713:B4V02 RS15320
gene id: 172713:B4V02_RS15320
uniprot id: A0A222WPB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS01825
gene id: 172713:B4V02_RS01825
uniprot id: A0A222WHB4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

172713:B4V02 RS24565
gene id: 172713:B4V02_RS24565
uniprot id: A0A222WV11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

172713:B4V02 RS20045
gene id: 172713:B4V02_RS20045
uniprot id: A0A222WS26
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity.

172713:B4V02 RS05040
gene id: 172713:B4V02_RS05040
uniprot id: A0A222WJZ3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

172713:B4V02 RS25265
gene id: 172713:B4V02_RS25265
uniprot id: A0A222WT10
names: Similarity
messages: Belongs to the ParB family.

172713:B4V02 RS18995
gene id: 172713:B4V02_RS18995
uniprot id: A0A222WRK1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

172713:B4V02 RS07840
gene id: 172713:B4V02_RS07840
uniprot id: A0A222WKD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

172713:B4V02 RS03160
gene id: 172713:B4V02_RS03160
uniprot id: A0A222WH86
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

172713:B4V02 RS06930
gene id: 172713:B4V02_RS06930
uniprot id: A0A222WKY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

172713:B4V02 RS15325
gene id: 172713:B4V02_RS15325
uniprot id: A0A222WN90
names: Subcellular Location Annotation
messages: Cytoplasm

172713:B4V02 RS02945
gene id: 172713:B4V02_RS02945
uniprot id: A0A222WIX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

172713:B4V02 RS12965
gene id: 172713:B4V02_RS12965
uniprot id: A0A222WNZ5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

172713:B4V02 RS01905
gene id: 172713:B4V02_RS01905
uniprot id: A0A222WUN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

172713:B4V02 RS17465
gene id: 172713:B4V02_RS17465
uniprot id: A0A222WR41
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

172713:B4V02 RS05905
gene id: 172713:B4V02_RS05905
uniprot id: A0A222WTF0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

172713:B4V02 RS25255
gene id: 172713:B4V02_RS25255
uniprot id: A0A222WTA5
names: Similarity
messages: Belongs to the ParB family.

172713:B4V02 RS22115
gene id: 172713:B4V02_RS22115
uniprot id: A0A222WT97
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS25225
gene id: 172713:B4V02_RS25225
uniprot id: A0A222WVD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

172713:B4V02 RS17065
gene id: 172713:B4V02_RS17065
uniprot id: A0A222WP38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

172713:B4V02 RS02325
gene id: 172713:B4V02_RS02325
uniprot id: A0A222WGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

172713:B4V02 RS25215
gene id: 172713:B4V02_RS25215
uniprot id: A0A222WVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

172713:B4V02 RS06920
gene id: 172713:B4V02_RS06920
uniprot id: A0A222WJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

172713:B4V02 RS02985
gene id: 172713:B4V02_RS02985
uniprot id: A0A222WIZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

172713:B4V02 RS24775
gene id: 172713:B4V02_RS24775
uniprot id: A0A222WV42
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

172713:B4V02 RS09680
gene id: 172713:B4V02_RS09680
uniprot id: A0A222WMC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

172713:B4V02 RS25335
gene id: 172713:B4V02_RS25335
uniprot id: A0A222WUV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS15730
gene id: 172713:B4V02_RS15730
uniprot id: A0A222WQA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

172713:B4V02 RS20990
gene id: 172713:B4V02_RS20990
uniprot id: A0A222WS25
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

172713:B4V02 RS03500
gene id: 172713:B4V02_RS03500
uniprot id: A0A222WHD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS10030
gene id: 172713:B4V02_RS10030
uniprot id: A0A222WLK6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

172713:B4V02 RS09265
gene id: 172713:B4V02_RS09265
uniprot id: A0A222WL61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS16165
gene id: 172713:B4V02_RS16165
uniprot id: A0A222WQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

172713:B4V02 RS08435
gene id: 172713:B4V02_RS08435
uniprot id: A0A222WKP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

172713:B4V02 RS21225
gene id: 172713:B4V02_RS21225
uniprot id: A0A222WR33
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

172713:B4V02 RS20070
gene id: 172713:B4V02_RS20070
uniprot id: A0A222WQF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS02900
gene id: 172713:B4V02_RS02900
uniprot id: A0A222WIC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

172713:B4V02 RS11505
gene id: 172713:B4V02_RS11505
uniprot id: A0A222WLD1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

172713:B4V02 RS00535
gene id: 172713:B4V02_RS00535
uniprot id: A0A222WFW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS20420
gene id: 172713:B4V02_RS20420
uniprot id: A0A222WSL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

172713:B4V02 RS10460
gene id: 172713:B4V02_RS10460
uniprot id: A0A222WKQ8
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

172713:B4V02 RS17820
gene id: 172713:B4V02_RS17820
uniprot id: A0A222WPG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

172713:B4V02 RS21515
gene id: 172713:B4V02_RS21515
uniprot id: A0A222WTK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

172713:B4V02 RS09375
gene id: 172713:B4V02_RS09375
uniprot id: A0A222WM63
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

172713:B4V02 RS08480
gene id: 172713:B4V02_RS08480
uniprot id: A0A222WL85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

172713:B4V02 RS22010
gene id: 172713:B4V02_RS22010
uniprot id: A0A222WTH3
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

172713:B4V02 RS14845
gene id: 172713:B4V02_RS14845
uniprot id: A0A222WPK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

172713:B4V02 RS05990
gene id: 172713:B4V02_RS05990
uniprot id: A0A222WKH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

172713:B4V02 RS15350
gene id: 172713:B4V02_RS15350
uniprot id: A0A222WPX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

172713:B4V02 RS02875
gene id: 172713:B4V02_RS02875
uniprot id: A0A222WH63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

172713:B4V02 RS24330
gene id: 172713:B4V02_RS24330
uniprot id: A0A222WUZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

172713:B4V02 RS24700
gene id: 172713:B4V02_RS24700
uniprot id: A0A222WSZ1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

172713:B4V02 RS15255
gene id: 172713:B4V02_RS15255
uniprot id: A0A222WQA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

172713:B4V02 RS02745
gene id: 172713:B4V02_RS02745
uniprot id: A0A222WIS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

172713:B4V02 RS21445
gene id: 172713:B4V02_RS21445
uniprot id: A0A222WR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS08795
gene id: 172713:B4V02_RS08795
uniprot id: A0A222WL83
names: Subcellular Location Annotation
messages: Cytoplasm

172713:B4V02 RS24710
gene id: 172713:B4V02_RS24710
uniprot id: A0A222WSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

172713:B4V02 RS15510
gene id: 172713:B4V02_RS15510
uniprot id: A0A222WQG4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

172713:B4V02 RS01805
gene id: 172713:B4V02_RS01805
uniprot id: A0A222WIC5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

172713:B4V02 RS21505
gene id: 172713:B4V02_RS21505
uniprot id: A0A222WR84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

172713:B4V02 RS02940
gene id: 172713:B4V02_RS02940
uniprot id: A0A222WI94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

172713:B4V02 RS08075
gene id: 172713:B4V02_RS08075
uniprot id: A0A222WKY5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

172713:B4V02 RS01665
gene id: 172713:B4V02_RS01665
uniprot id: A0A222WHD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

172713:B4V02 RS11625
gene id: 172713:B4V02_RS11625
uniprot id: A0A222WLD2
names: Similarity
messages: Belongs to the PspA/IM30 family.

172713:B4V02 RS02870
gene id: 172713:B4V02_RS02870
uniprot id: A0A222WI95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

172713:B4V02 RS05925
gene id: 172713:B4V02_RS05925
uniprot id: A0A222WIJ0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

172713:B4V02 RS17225
gene id: 172713:B4V02_RS17225
uniprot id: A0A222WQN2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

172713:B4V02 RS20075
gene id: 172713:B4V02_RS20075
uniprot id: A0A222WSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS21975
gene id: 172713:B4V02_RS21975
uniprot id: A0A222WRF0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

172713:B4V02 RS10690
gene id: 172713:B4V02_RS10690
uniprot id: A0A222WN00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

172713:B4V02 RS23935
gene id: 172713:B4V02_RS23935
uniprot id: A0A222WS77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS17230
gene id: 172713:B4V02_RS17230
uniprot id: A0A222WPB8
names: Similarity
messages: Belongs to the Dps family.

172713:B4V02 RS12365
gene id: 172713:B4V02_RS12365
uniprot id: A0A222WLP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

172713:B4V02 RS00880
gene id: 172713:B4V02_RS00880
uniprot id: A0A222WHX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS17695
gene id: 172713:B4V02_RS17695
uniprot id: A0A222WQH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

172713:B4V02 RS10400
gene id: 172713:B4V02_RS10400
uniprot id: A0A222WKT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

172713:B4V02 RS17760
gene id: 172713:B4V02_RS17760
uniprot id: A0A222WQH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

172713:B4V02 RS01935
gene id: 172713:B4V02_RS01935
uniprot id: A0A222WHD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

172713:B4V02 RS06540
gene id: 172713:B4V02_RS06540
uniprot id: A0A222WKR6
names: Similarity
messages: Belongs to the UPF0297 family.

172713:B4V02 RS25030
gene id: 172713:B4V02_RS25030
uniprot id: A0A222WUK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

172713:B4V02 RS15250
gene id: 172713:B4V02_RS15250
uniprot id: A0A222WPV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

172713:B4V02 RS15445
gene id: 172713:B4V02_RS15445
uniprot id: A0A222WN72
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

172713:B4V02 RS10450
gene id: 172713:B4V02_RS10450
uniprot id: A0A222WKU5
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS14795
gene id: 172713:B4V02_RS14795
uniprot id: A0A222WPJ9
names: Similarity
messages: Belongs to the WXG100 family.

172713:B4V02 RS15370
gene id: 172713:B4V02_RS15370
uniprot id: A0A222WPL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

172713:B4V02 RS00495
gene id: 172713:B4V02_RS00495
uniprot id: A0A222WH62
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

172713:B4V02 RS02995
gene id: 172713:B4V02_RS02995
uniprot id: A0A222WIY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

172713:B4V02 RS08490
gene id: 172713:B4V02_RS08490
uniprot id: A0A222WKS9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

172713:B4V02 RS25520
gene id: 172713:B4V02_RS25520
uniprot id: A0A222WUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

172713:B4V02 RS23360
gene id: 172713:B4V02_RS23360
uniprot id: A0A222WS36
names: Similarity
messages: Belongs to the UDPGP type 2 family.

172713:B4V02 RS17720
gene id: 172713:B4V02_RS17720
uniprot id: A0A222WVJ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

172713:B4V02 RS09660
gene id: 172713:B4V02_RS09660
uniprot id: A0A222WKE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

172713:B4V02 RS11045
gene id: 172713:B4V02_RS11045
uniprot id: A0A222WM53
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

172713:B4V02 RS24270
gene id: 172713:B4V02_RS24270
uniprot id: A0A222WUY3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

172713:B4V02 RS05145
gene id: 172713:B4V02_RS05145
uniprot id: A0A222WI63
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

172713:B4V02 RS08195
gene id: 172713:B4V02_RS08195
uniprot id: A0A222WKW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

172713:B4V02 RS14425
gene id: 172713:B4V02_RS14425
uniprot id: A0A222WPP9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

172713:B4V02 RS17045
gene id: 172713:B4V02_RS17045
uniprot id: A0A222WRC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

172713:B4V02 RS25055
gene id: 172713:B4V02_RS25055
uniprot id: A0A222WUQ8
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

172713:B4V02 RS02730
gene id: 172713:B4V02_RS02730
uniprot id: A0A222WH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

172713:B4V02 RS20305
gene id: 172713:B4V02_RS20305
uniprot id: A0A222WSK0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

172713:B4V02 RS24325
gene id: 172713:B4V02_RS24325
uniprot id: A0A222WSH7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

172713:B4V02 RS22745
gene id: 172713:B4V02_RS22745
uniprot id: A0A222WRR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

172713:B4V02 RS15385
gene id: 172713:B4V02_RS15385
uniprot id: A0A222WPP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

172713:B4V02 RS06050
gene id: 172713:B4V02_RS06050
uniprot id: A0A222WKI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

172713:B4V02 RS11320
gene id: 172713:B4V02_RS11320
uniprot id: A0A222WMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

172713:B4V02 RS00150
gene id: 172713:B4V02_RS00150
uniprot id: A0A222WHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

172713:B4V02 RS02195
gene id: 172713:B4V02_RS02195
uniprot id: A0A222WHZ2
names: Similarity
messages: Belongs to the FlgM family.

172713:B4V02 RS15970
gene id: 172713:B4V02_RS15970
uniprot id: A0A222WNP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS16650
gene id: 172713:B4V02_RS16650
uniprot id: A0A222WQT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

172713:B4V02 RS10510
gene id: 172713:B4V02_RS10510
uniprot id: A0A222WKS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

172713:B4V02 RS02510
gene id: 172713:B4V02_RS02510
uniprot id: A0A222WI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

172713:B4V02 RS08675
gene id: 172713:B4V02_RS08675
uniprot id: A0A222WJU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

172713:B4V02 RS02970
gene id: 172713:B4V02_RS02970
uniprot id: A0A222WIB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

172713:B4V02 RS03950
gene id: 172713:B4V02_RS03950
uniprot id: A0A222WIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

172713:B4V02 RS02790
gene id: 172713:B4V02_RS02790
uniprot id: A0A222WI64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

172713:B4V02 RS09885
gene id: 172713:B4V02_RS09885
uniprot id: A0A222WLV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

172713:B4V02 RS24930
gene id: 172713:B4V02_RS24930
uniprot id: A0A222WST7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

172713:B4V02 RS17645
gene id: 172713:B4V02_RS17645
uniprot id: A0A222WQG1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

172713:B4V02 RS24255
gene id: 172713:B4V02_RS24255
uniprot id: A0A222WU86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

172713:B4V02 RS24380
gene id: 172713:B4V02_RS24380
uniprot id: A0A222WTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

172713:B4V02 RS15345
gene id: 172713:B4V02_RS15345
uniprot id: A0A222WQB9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

172713:B4V02 RS18485
gene id: 172713:B4V02_RS18485
uniprot id: A0A222WPW9
names: Similarity
messages: Belongs to the IMPACT family.

172713:B4V02 RS03030
gene id: 172713:B4V02_RS03030
uniprot id: A0A222WHB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

172713:B4V02 RS05790
gene id: 172713:B4V02_RS05790
uniprot id: A0A222WJG1
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

172713:B4V02 RS22450
gene id: 172713:B4V02_RS22450
uniprot id: A0A222WRT6
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS10060
gene id: 172713:B4V02_RS10060
uniprot id: A0A222WLW4
names: Similarity
messages: Belongs to the TlyA family.

172713:B4V02 RS01955
gene id: 172713:B4V02_RS01955
uniprot id: A0A222WGS0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

172713:B4V02 RS22015
gene id: 172713:B4V02_RS22015
uniprot id: A0A222WT75
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

172713:B4V02 RS10940
gene id: 172713:B4V02_RS10940
uniprot id: A0A222WL36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

172713:B4V02 RS03635
gene id: 172713:B4V02_RS03635
uniprot id: A0A222WI13
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

172713:B4V02 RS00085
gene id: 172713:B4V02_RS00085
uniprot id: A0A222WFT3
names: Similarity
messages: Belongs to the YjdM family.

172713:B4V02 RS00900
gene id: 172713:B4V02_RS00900
uniprot id: A0A222WGT2
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

172713:B4V02 RS25220
gene id: 172713:B4V02_RS25220
uniprot id: A0A222WT09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

172713:B4V02 RS04825
gene id: 172713:B4V02_RS04825
uniprot id: A0A222WHZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

172713:B4V02 RS11340
gene id: 172713:B4V02_RS11340
uniprot id: A0A222WMA4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

172713:B4V02 RS15040
gene id: 172713:B4V02_RS15040
uniprot id: A0A222WPR7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS09525
gene id: 172713:B4V02_RS09525
uniprot id: A0A222WK91
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS03170
gene id: 172713:B4V02_RS03170
uniprot id: A0A222WJ22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

172713:B4V02 RS15295
gene id: 172713:B4V02_RS15295
uniprot id: A0A222WQA9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

172713:B4V02 RS21015
gene id: 172713:B4V02_RS21015
uniprot id: A0A222WTA8
names: Subcellular Location Annotation
messages: Cell membrane

172713:B4V02 RS05820
gene id: 172713:B4V02_RS05820
uniprot id: A0A222WJP4
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

172713:B4V02 RS11220
gene id: 172713:B4V02_RS11220
uniprot id: A0A222WL82
names: Similarity
messages: Belongs to the glutamine synthetase family.

172713:B4V02 RS11000
gene id: 172713:B4V02_RS11000
uniprot id: A0A222WL46
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS04455
gene id: 172713:B4V02_RS04455
uniprot id: A0A222WJL9
names: Similarity
messages: Belongs to the PspA/IM30 family.

172713:B4V02 RS15410
gene id: 172713:B4V02_RS15410
uniprot id: A0A222WQD9
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

172713:B4V02 RS02965
gene id: 172713:B4V02_RS02965
uniprot id: A0A222WH80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

172713:B4V02 RS10220
gene id: 172713:B4V02_RS10220
uniprot id: A0A222WMR4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

172713:B4V02 RS22755
gene id: 172713:B4V02_RS22755
uniprot id: A0A222WTM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

172713:B4V02 RS00375
gene id: 172713:B4V02_RS00375
uniprot id: A0A222WHQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS02700
gene id: 172713:B4V02_RS02700
uniprot id: A0A222WI87
names: Similarity
messages: Belongs to the CtsR family.

172713:B4V02 RS04505
gene id: 172713:B4V02_RS04505
uniprot id: A0A222WJP9
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

172713:B4V02 RS05835
gene id: 172713:B4V02_RS05835
uniprot id: A0A222WJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS08670
gene id: 172713:B4V02_RS08670
uniprot id: A0A222WJU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

172713:B4V02 RS20120
gene id: 172713:B4V02_RS20120
uniprot id: A0A222WQG9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

172713:B4V02 RS02090
gene id: 172713:B4V02_RS02090
uniprot id: A0A222WHT5
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS08250
gene id: 172713:B4V02_RS08250
uniprot id: A0A222WJM3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

172713:B4V02 RS16420
gene id: 172713:B4V02_RS16420
uniprot id: A0A222WQG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

172713:B4V02 RS22355
gene id: 172713:B4V02_RS22355
uniprot id: A0A222WRP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

172713:B4V02 RS04945
gene id: 172713:B4V02_RS04945
uniprot id: A0A222WJC9
names: Similarity
messages: Belongs to the thioredoxin family.

172713:B4V02 RS09445
gene id: 172713:B4V02_RS09445
uniprot id: A0A222WL77
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

172713:B4V02 RS01385
gene id: 172713:B4V02_RS01385
uniprot id: A0A222WHT7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

172713:B4V02 RS02085
gene id: 172713:B4V02_RS02085
uniprot id: A0A222WTJ8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

172713:B4V02 RS24730
gene id: 172713:B4V02_RS24730
uniprot id: A0A222WV33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

172713:B4V02 RS15465
gene id: 172713:B4V02_RS15465
uniprot id: A0A222WQ09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

172713:B4V02 RS01810
gene id: 172713:B4V02_RS01810
uniprot id: A0A222WHQ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

172713:B4V02 RS14895
gene id: 172713:B4V02_RS14895
uniprot id: A0A222WPL9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

172713:B4V02 RS01855
gene id: 172713:B4V02_RS01855
uniprot id: A0A222WGP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS25250
gene id: 172713:B4V02_RS25250
uniprot id: A0A222WUC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

172713:B4V02 RS08420
gene id: 172713:B4V02_RS08420
uniprot id: A0A222WL10
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

172713:B4V02 RS02850
gene id: 172713:B4V02_RS02850
uniprot id: A0A222WIB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

172713:B4V02 RS14925
gene id: 172713:B4V02_RS14925
uniprot id: A0A222WMX5
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

172713:B4V02 RS02895
gene id: 172713:B4V02_RS02895
uniprot id: A0A222WIW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

172713:B4V02 RS25230
gene id: 172713:B4V02_RS25230
uniprot id: A0A222WUT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

172713:B4V02 RS10675
gene id: 172713:B4V02_RS10675
uniprot id: A0A222WMB5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

172713:B4V02 RS01580
gene id: 172713:B4V02_RS01580
uniprot id: A0A222WGJ6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

172713:B4V02 RS02845
gene id: 172713:B4V02_RS02845
uniprot id: A0A222WIU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

172713:B4V02 RS25465
gene id: 172713:B4V02_RS25465
uniprot id: A0A222WUH5
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

172713:B4V02 RS02825
gene id: 172713:B4V02_RS02825
uniprot id: A0A222WH58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

172713:B4V02 RS20020
gene id: 172713:B4V02_RS20020
uniprot id: A0A222WQE8
names: Similarity
messages: Belongs to the NifX/NifY family.

172713:B4V02 RS08285
gene id: 172713:B4V02_RS08285
uniprot id: A0A222WJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

172713:B4V02 RS10180
gene id: 172713:B4V02_RS10180
uniprot id: A0A222WMJ3
names: Similarity
messages: Belongs to the Fur family.

172713:B4V02 RS02715
gene id: 172713:B4V02_RS02715
uniprot id: A0A222WH48
names: Similarity
messages: Belongs to the ClpA/ClpB family.

172713:B4V02 RS10155
gene id: 172713:B4V02_RS10155
uniprot id: A0A222WM15
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

172713:B4V02 RS25380
gene id: 172713:B4V02_RS25380
uniprot id: A0A222WT27
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

172713:B4V02 RS25385
gene id: 172713:B4V02_RS25385
uniprot id: A0A222WT36
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

172713:B4V02 RS15400
gene id: 172713:B4V02_RS15400
uniprot id: A0A222WQC4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

172713:B4V02 RS03650
gene id: 172713:B4V02_RS03650
uniprot id: A0A222WHH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

172713:B4V02 RS00270
gene id: 172713:B4V02_RS00270
uniprot id: A0A222WGY1
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS04005
gene id: 172713:B4V02_RS04005
uniprot id: A0A222WJE9
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS24545
gene id: 172713:B4V02_RS24545
uniprot id: A0A222WSP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS18490
gene id: 172713:B4V02_RS18490
uniprot id: A0A222WPQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS15305
gene id: 172713:B4V02_RS15305
uniprot id: A0A222WQB7
names: Similarity
messages: Belongs to the FlgD family.

172713:B4V02 RS19830
gene id: 172713:B4V02_RS19830
uniprot id: A0A222WRI9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

172713:B4V02 RS19310
gene id: 172713:B4V02_RS19310
uniprot id: A0A222WQ82
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

172713:B4V02 RS00295
gene id: 172713:B4V02_RS00295
uniprot id: A0A222WFY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

172713:B4V02 RS03165
gene id: 172713:B4V02_RS03165
uniprot id: A0A222WHC4
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

172713:B4V02 RS22095
gene id: 172713:B4V02_RS22095
uniprot id: A0A222WRJ3
names: Subcellular Location Annotation
messages: Cytoplasm

172713:B4V02 RS25375
gene id: 172713:B4V02_RS25375
uniprot id: A0A222WUS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

172713:B4V02 RS22090
gene id: 172713:B4V02_RS22090
uniprot id: A0A222WT96
names: Subcellular Location Annotation
messages: Cytoplasm

172713:B4V02 RS02800
gene id: 172713:B4V02_RS02800
uniprot id: A0A222WIA5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

172713:B4V02 RS25320
gene id: 172713:B4V02_RS25320
uniprot id: A0A222WT18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

172713:B4V02 RS15565
gene id: 172713:B4V02_RS15565
uniprot id: A0A222WQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

172713:B4V02 RS01350
gene id: 172713:B4V02_RS01350
uniprot id: A0A222WH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS01990
gene id: 172713:B4V02_RS01990
uniprot id: A0A222WHI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

172713:B4V02 RS09920
gene id: 172713:B4V02_RS09920
uniprot id: A0A222WLG2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

172713:B4V02 RS15500
gene id: 172713:B4V02_RS15500
uniprot id: A0A222WQE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

172713:B4V02 RS16305
gene id: 172713:B4V02_RS16305
uniprot id: A0A222WNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

172713:B4V02 RS02000
gene id: 172713:B4V02_RS02000
uniprot id: A0A222WHQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

172713:B4V02 RS09615
gene id: 172713:B4V02_RS09615
uniprot id: A0A222WLQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

172713:B4V02 RS02840
gene id: 172713:B4V02_RS02840
uniprot id: A0A222WI72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

172713:B4V02 RS10275
gene id: 172713:B4V02_RS10275
uniprot id: A0A222WM00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

172713:B4V02 RS08200
gene id: 172713:B4V02_RS08200
uniprot id: A0A222WLI4
names: Similarity
messages: Belongs to the CvfB family.

172713:B4V02 RS06010
gene id: 172713:B4V02_RS06010
uniprot id: A0A222WJ89
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

172713:B4V02 RS25040
gene id: 172713:B4V02_RS25040
uniprot id: A0A222WW99
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

172713:B4V02 RS15075
gene id: 172713:B4V02_RS15075
uniprot id: A0A222WPH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

172713:B4V02 RS08895
gene id: 172713:B4V02_RS08895
uniprot id: A0A222WJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS13760
gene id: 172713:B4V02_RS13760
uniprot id: A0A222WNU8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

172713:B4V02 RS14670
gene id: 172713:B4V02_RS14670
uniprot id: A0A222WMS8
names: Subcellular Location Annotation
messages: Cytoplasm

172713:B4V02 RS08715
gene id: 172713:B4V02_RS08715
uniprot id: A0A222WL98
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS09520
gene id: 172713:B4V02_RS09520
uniprot id: A0A222WK85
names: Similarity
messages: Belongs to the asp23 family.

172713:B4V02 RS08330
gene id: 172713:B4V02_RS08330
uniprot id: A0A222WKM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

172713:B4V02 RS02990
gene id: 172713:B4V02_RS02990
uniprot id: A0A222WIA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

172713:B4V02 RS14970
gene id: 172713:B4V02_RS14970
uniprot id: A0A222WN49
names: Similarity
messages: Belongs to the UPF0234 family.

172713:B4V02 RS12265
gene id: 172713:B4V02_RS12265
uniprot id: A0A222WMM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

172713:B4V02 RS15170
gene id: 172713:B4V02_RS15170
uniprot id: A0A222WN59
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

172713:B4V02 RS06180
gene id: 172713:B4V02_RS06180
uniprot id: A0A222WKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

172713:B4V02 RS24530
gene id: 172713:B4V02_RS24530
uniprot id: A0A222WTY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

172713:B4V02 RS19065
gene id: 172713:B4V02_RS19065
uniprot id: A0A222WRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

172713:B4V02 RS20705
gene id: 172713:B4V02_RS20705
uniprot id: A0A222WSI9
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS02220
gene id: 172713:B4V02_RS02220
uniprot id: A0A222WGV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

172713:B4V02 RS24285
gene id: 172713:B4V02_RS24285
uniprot id: A0A222WUP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

172713:B4V02 RS20395
gene id: 172713:B4V02_RS20395
uniprot id: A0A222WQL2
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

172713:B4V02 RS21030
gene id: 172713:B4V02_RS21030
uniprot id: A0A222WSX1
names: Similarity
messages: Belongs to the UPF0111 family.

172713:B4V02 RS15355
gene id: 172713:B4V02_RS15355
uniprot id: A0A222WQC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

172713:B4V02 RS01985
gene id: 172713:B4V02_RS01985
uniprot id: A0A222WHE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

172713:B4V02 RS07080
gene id: 172713:B4V02_RS07080
uniprot id: A0A222WJ32
names: Similarity
messages: Belongs to the ABC transporter superfamily.

172713:B4V02 RS17510
gene id: 172713:B4V02_RS17510
uniprot id: A0A222WRG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS12260
gene id: 172713:B4V02_RS12260
uniprot id: A0A222WNB3
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

172713:B4V02 RS09565
gene id: 172713:B4V02_RS09565
uniprot id: A0A222WLQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

172713:B4V02 RS16225
gene id: 172713:B4V02_RS16225
uniprot id: A0A222WNP4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

172713:B4V02 RS11345
gene id: 172713:B4V02_RS11345
uniprot id: A0A222WLA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

172713:B4V02 RS21010
gene id: 172713:B4V02_RS21010
uniprot id: A0A222WQV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

172713:B4V02 RS24935
gene id: 172713:B4V02_RS24935
uniprot id: A0A222WSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

172713:B4V02 RS08130
gene id: 172713:B4V02_RS08130
uniprot id: A0A222WJK1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

172713:B4V02 RS15470
gene id: 172713:B4V02_RS15470
uniprot id: A0A222WPP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

172713:B4V02 RS20385
gene id: 172713:B4V02_RS20385
uniprot id: A0A222WSB8
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

172713:B4V02 RS24875
gene id: 172713:B4V02_RS24875
uniprot id: A0A222WUI3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

172713:B4V02 RS02880
gene id: 172713:B4V02_RS02880
uniprot id: A0A222WH92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

172713:B4V02 RS22640
gene id: 172713:B4V02_RS22640
uniprot id: A0A222WRQ4
names: Similarity
messages: Belongs to the UPF0045 family.

172713:B4V02 RS18215
gene id: 172713:B4V02_RS18215
uniprot id: A0A222WPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

172713:B4V02 RS25310
gene id: 172713:B4V02_RS25310
uniprot id: A0A222WTB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

172713:B4V02 RS10245
gene id: 172713:B4V02_RS10245
uniprot id: A0A222WLP2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

172713:B4V02 RS10395
gene id: 172713:B4V02_RS10395
uniprot id: A0A222WLS1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

172713:B4V02 RS01975
gene id: 172713:B4V02_RS01975
uniprot id: A0A222WIE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

172713:B4V02 RS22250
gene id: 172713:B4V02_RS22250
uniprot id: A0A222WRM7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

172713:B4V02 RS11575
gene id: 172713:B4V02_RS11575
uniprot id: A0A222WLC3
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS22245
gene id: 172713:B4V02_RS22245
uniprot id: A0A222WTC5
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

172713:B4V02 RS18510
gene id: 172713:B4V02_RS18510
uniprot id: A0A222WRS7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

172713:B4V02 RS15055
gene id: 172713:B4V02_RS15055
uniprot id: A0A222WP96
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

172713:B4V02 RS02010
gene id: 172713:B4V02_RS02010
uniprot id: A0A222WGR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

172713:B4V02 RS01995
gene id: 172713:B4V02_RS01995
uniprot id: A0A222WGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

172713:B4V02 RS02855
gene id: 172713:B4V02_RS02855
uniprot id: A0A222WHQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

172713:B4V02 RS24850
gene id: 172713:B4V02_RS24850
uniprot id: A0A222WV55
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

172713:B4V02 RS17220
gene id: 172713:B4V02_RS17220
uniprot id: A0A222WP66
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

172713:B4V02 RS25110
gene id: 172713:B4V02_RS25110
uniprot id: A0A222WVA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

172713:B4V02 RS06340
gene id: 172713:B4V02_RS06340
uniprot id: A0A222WK45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

172713:B4V02 RS25625
gene id: 172713:B4V02_RS25625
uniprot id: A0A222WV30
names: Similarity
messages: Belongs to the MQO family.

172713:B4V02 RS21790
gene id: 172713:B4V02_RS21790
uniprot id: A0A222WT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS24720
gene id: 172713:B4V02_RS24720
uniprot id: A0A222WV32
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

172713:B4V02 RS23375
gene id: 172713:B4V02_RS23375
uniprot id: A0A222WTW8
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

172713:B4V02 RS23845
gene id: 172713:B4V02_RS23845
uniprot id: A0A222WUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

172713:B4V02 RS05870
gene id: 172713:B4V02_RS05870
uniprot id: A0A222WKF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

172713:B4V02 RS10640
gene id: 172713:B4V02_RS10640
uniprot id: A0A222WMZ2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

172713:B4V02 RS09605
gene id: 172713:B4V02_RS09605
uniprot id: A0A222WLC0
names: Similarity
messages: Belongs to the RemA family.

172713:B4V02 RS15115
gene id: 172713:B4V02_RS15115
uniprot id: A0A222WP73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

172713:B4V02 RS16285
gene id: 172713:B4V02_RS16285
uniprot id: A0A222WQ60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

172713:B4V02 RS10070
gene id: 172713:B4V02_RS10070
uniprot id: A0A222WTI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

172713:B4V02 RS00620
gene id: 172713:B4V02_RS00620
uniprot id: A0A222WGS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS01160
gene id: 172713:B4V02_RS01160
uniprot id: A0A222WHB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

172713:B4V02 RS08605
gene id: 172713:B4V02_RS08605
uniprot id: A0A222WKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

172713:B4V02 RS02860
gene id: 172713:B4V02_RS02860
uniprot id: A0A222WI02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

172713:B4V02 RS19545
gene id: 172713:B4V02_RS19545
uniprot id: A0A222WSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

172713:B4V02 RS21165
gene id: 172713:B4V02_RS21165
uniprot id: A0A222WSR5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

172713:B4V02 RS11145
gene id: 172713:B4V02_RS11145
uniprot id: A0A222WV76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

172713:B4V02 RS00610
gene id: 172713:B4V02_RS00610
uniprot id: A0A222WGQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS15095
gene id: 172713:B4V02_RS15095
uniprot id: A0A222WPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

172713:B4V02 RS15365
gene id: 172713:B4V02_RS15365
uniprot id: A0A222WVE8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

172713:B4V02 RS08515
gene id: 172713:B4V02_RS08515
uniprot id: A0A222WJR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

172713:B4V02 RS16275
gene id: 172713:B4V02_RS16275
uniprot id: A0A222WPT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

172713:B4V02 RS06835
gene id: 172713:B4V02_RS06835
uniprot id: A0A222WJP8
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS24985
gene id: 172713:B4V02_RS24985
uniprot id: A0A222WSX3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

172713:B4V02 RS25475
gene id: 172713:B4V02_RS25475
uniprot id: A0A222WUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS04795
gene id: 172713:B4V02_RS04795
uniprot id: A0A222WIK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS19205
gene id: 172713:B4V02_RS19205
uniprot id: A0A222WQ65
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS11605
gene id: 172713:B4V02_RS11605
uniprot id: A0A222WMF5
names: Subcellular Location Annotation
messages: Cell membrane

172713:B4V02 RS10520
gene id: 172713:B4V02_RS10520
uniprot id: A0A222WMX3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

172713:B4V02 RS06185
gene id: 172713:B4V02_RS06185
uniprot id: A0A222WK12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

172713:B4V02 RS02810
gene id: 172713:B4V02_RS02810
uniprot id: A0A222WHZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

172713:B4V02 RS09515
gene id: 172713:B4V02_RS09515
uniprot id: A0A222WLP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

172713:B4V02 RS17035
gene id: 172713:B4V02_RS17035
uniprot id: A0A222WR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS02915
gene id: 172713:B4V02_RS02915
uniprot id: A0A222WH75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

172713:B4V02 RS21230
gene id: 172713:B4V02_RS21230
uniprot id: A0A222WQZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

172713:B4V02 RS15460
gene id: 172713:B4V02_RS15460
uniprot id: A0A222WQF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

172713:B4V02 RS12900
gene id: 172713:B4V02_RS12900
uniprot id: A0A222WV95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

172713:B4V02 RS15280
gene id: 172713:B4V02_RS15280
uniprot id: A0A222WPM0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

172713:B4V02 RS08265
gene id: 172713:B4V02_RS08265
uniprot id: A0A222WLJ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

172713:B4V02 RS24765
gene id: 172713:B4V02_RS24765
uniprot id: A0A222WSR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

172713:B4V02 RS25020
gene id: 172713:B4V02_RS25020
uniprot id: A0A222WU71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

172713:B4V02 RS01980
gene id: 172713:B4V02_RS01980
uniprot id: A0A222WHQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

172713:B4V02 RS02720
gene id: 172713:B4V02_RS02720
uniprot id: A0A222WI67
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

172713:B4V02 RS06970
gene id: 172713:B4V02_RS06970
uniprot id: A0A222WKD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS17205
gene id: 172713:B4V02_RS17205
uniprot id: A0A222WR59
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

172713:B4V02 RS02960
gene id: 172713:B4V02_RS02960
uniprot id: A0A222WI22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

172713:B4V02 RS02795
gene id: 172713:B4V02_RS02795
uniprot id: A0A222WIT7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

172713:B4V02 RS09880
gene id: 172713:B4V02_RS09880
uniprot id: A0A222WKI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

172713:B4V02 RS16925
gene id: 172713:B4V02_RS16925
uniprot id: A0A222WQP9
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

172713:B4V02 RS10210
gene id: 172713:B4V02_RS10210
uniprot id: A0A222WKL4
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

172713:B4V02 RS05325
gene id: 172713:B4V02_RS05325
uniprot id: A0A222WJK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS08495
gene id: 172713:B4V02_RS08495
uniprot id: A0A222WJU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

172713:B4V02 RS10020
gene id: 172713:B4V02_RS10020
uniprot id: A0A222WM16
names: Similarity
messages: Belongs to the asp23 family.

172713:B4V02 RS21255
gene id: 172713:B4V02_RS21255
uniprot id: A0A222WVD8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

172713:B4V02 RS08300
gene id: 172713:B4V02_RS08300
uniprot id: A0A222WJN1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

172713:B4V02 RS17600
gene id: 172713:B4V02_RS17600
uniprot id: A0A222WPC8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

172713:B4V02 RS15130
gene id: 172713:B4V02_RS15130
uniprot id: A0A222WN83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

172713:B4V02 RS08760
gene id: 172713:B4V02_RS08760
uniprot id: A0A222WKV2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

172713:B4V02 RS02905
gene id: 172713:B4V02_RS02905
uniprot id: A0A222WHR5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

172713:B4V02 RS13475
gene id: 172713:B4V02_RS13475
uniprot id: A0A222WNX2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

172713:B4V02 RS15165
gene id: 172713:B4V02_RS15165
uniprot id: A0A222WP85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

172713:B4V02 RS02755
gene id: 172713:B4V02_RS02755
uniprot id: A0A222WHN6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

172713:B4V02 RS14290
gene id: 172713:B4V02_RS14290
uniprot id: A0A222WMP6
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS18755
gene id: 172713:B4V02_RS18755
uniprot id: A0A222WQ05
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

172713:B4V02 RS17105
gene id: 172713:B4V02_RS17105
uniprot id: A0A222WQP4
names: Similarity
messages: Belongs to the UPF0342 family.

172713:B4V02 RS16730
gene id: 172713:B4V02_RS16730
uniprot id: A0A222WP26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

172713:B4V02 RS08665
gene id: 172713:B4V02_RS08665
uniprot id: A0A222WL88
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

172713:B4V02 RS02925
gene id: 172713:B4V02_RS02925
uniprot id: A0A222WH72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

172713:B4V02 RS23045
gene id: 172713:B4V02_RS23045
uniprot id: A0A222WTR5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

172713:B4V02 RS15135
gene id: 172713:B4V02_RS15135
uniprot id: A0A222WN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

172713:B4V02 RS03630
gene id: 172713:B4V02_RS03630
uniprot id: A0A222WUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

172713:B4V02 RS02005
gene id: 172713:B4V02_RS02005
uniprot id: A0A222WGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

172713:B4V02 RS20390
gene id: 172713:B4V02_RS20390
uniprot id: A0A222WQQ4
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

172713:B4V02 RS14235
gene id: 172713:B4V02_RS14235
uniprot id: A0A222WNQ9
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS07170
gene id: 172713:B4V02_RS07170
uniprot id: A0A222WK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS10920
gene id: 172713:B4V02_RS10920
uniprot id: A0A222WMX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

172713:B4V02 RS05045
gene id: 172713:B4V02_RS05045
uniprot id: A0A222WJB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

172713:B4V02 RS06005
gene id: 172713:B4V02_RS06005
uniprot id: A0A222WJY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

172713:B4V02 RS02025
gene id: 172713:B4V02_RS02025
uniprot id: A0A222WHT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS00440
gene id: 172713:B4V02_RS00440
uniprot id: A0A222WH25
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

172713:B4V02 RS13505
gene id: 172713:B4V02_RS13505
uniprot id: A0A222WM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

172713:B4V02 RS15020
gene id: 172713:B4V02_RS15020
uniprot id: A0A222WPG6
names: Similarity
messages: Belongs to the peptidase S14 family.

172713:B4V02 RS06160
gene id: 172713:B4V02_RS06160
uniprot id: A0A222WIN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

172713:B4V02 RS06670
gene id: 172713:B4V02_RS06670
uniprot id: A0A222WJL8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

172713:B4V02 RS15260
gene id: 172713:B4V02_RS15260
uniprot id: A0A222WPW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

172713:B4V02 RS06040
gene id: 172713:B4V02_RS06040
uniprot id: A0A222WIL0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

172713:B4V02 RS09500
gene id: 172713:B4V02_RS09500
uniprot id: A0A222WL89
names: Similarity
messages: Belongs to the peptidase M29 family.

172713:B4V02 RS01245
gene id: 172713:B4V02_RS01245
uniprot id: A0A222WH93
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS03715
gene id: 172713:B4V02_RS03715
uniprot id: A0A222WIN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS14945
gene id: 172713:B4V02_RS14945
uniprot id: A0A222WPM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

172713:B4V02 RS10425
gene id: 172713:B4V02_RS10425
uniprot id: A0A222WM31
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

172713:B4V02 RS16335
gene id: 172713:B4V02_RS16335
uniprot id: A0A222WQ54
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS13465
gene id: 172713:B4V02_RS13465
uniprot id: A0A222WNR8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

172713:B4V02 RS06545
gene id: 172713:B4V02_RS06545
uniprot id: A0A222WK23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

172713:B4V02 RS10360
gene id: 172713:B4V02_RS10360
uniprot id: A0A222WKN6
names: Similarity
messages: Belongs to the MecA family.

172713:B4V02 RS03915
gene id: 172713:B4V02_RS03915
uniprot id: A0A222WI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS06235
gene id: 172713:B4V02_RS06235
uniprot id: A0A222WK22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

172713:B4V02 RS00720
gene id: 172713:B4V02_RS00720
uniprot id: A0A222WGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

172713:B4V02 RS10455
gene id: 172713:B4V02_RS10455
uniprot id: A0A222WM76
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

172713:B4V02 RS01045
gene id: 172713:B4V02_RS01045
uniprot id: A0A222WHZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS24540
gene id: 172713:B4V02_RS24540
uniprot id: A0A222WUB7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS02930
gene id: 172713:B4V02_RS02930
uniprot id: A0A222WH97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

172713:B4V02 RS12080
gene id: 172713:B4V02_RS12080
uniprot id: A0A222WLP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

172713:B4V02 RS13715
gene id: 172713:B4V02_RS13715
uniprot id: A0A222WMC9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

172713:B4V02 RS04615
gene id: 172713:B4V02_RS04615
uniprot id: A0A222WJR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

172713:B4V02 RS24560
gene id: 172713:B4V02_RS24560
uniprot id: A0A222WUH0
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

172713:B4V02 RS04315
gene id: 172713:B4V02_RS04315
uniprot id: A0A222WJK9
names: Similarity
messages: Belongs to the Fur family.

172713:B4V02 RS08505
gene id: 172713:B4V02_RS08505
uniprot id: A0A222WJR6
names: Similarity
messages: Belongs to the UPF0178 family.

172713:B4V02 RS14130
gene id: 172713:B4V02_RS14130
uniprot id: A0A222WNN9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

172713:B4V02 RS10725
gene id: 172713:B4V02_RS10725
uniprot id: A0A222WKZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

172713:B4V02 RS11630
gene id: 172713:B4V02_RS11630
uniprot id: A0A222WLE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

172713:B4V02 RS25210
gene id: 172713:B4V02_RS25210
uniprot id: A0A222WT03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

172713:B4V02 RS24915
gene id: 172713:B4V02_RS24915
uniprot id: A0A222WU51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

172713:B4V02 RS08310
gene id: 172713:B4V02_RS08310
uniprot id: A0A222WLM1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

172713:B4V02 RS03025
gene id: 172713:B4V02_RS03025
uniprot id: A0A222WH81
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

172713:B4V02 RS06555
gene id: 172713:B4V02_RS06555
uniprot id: A0A222WK84
names: Similarity
messages: Belongs to the UPF0473 family.

172713:B4V02 RS08325
gene id: 172713:B4V02_RS08325
uniprot id: A0A222WL52
names: Subcellular Location Annotation
messages: Cytoplasm

172713:B4V02 RS03000
gene id: 172713:B4V02_RS03000
uniprot id: A0A222WIE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

172713:B4V02 RS15245
gene id: 172713:B4V02_RS15245
uniprot id: A0A222WQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

172713:B4V02 RS17060
gene id: 172713:B4V02_RS17060
uniprot id: A0A222WQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

172713:B4V02 RS12895
gene id: 172713:B4V02_RS12895
uniprot id: A0A222WLY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

172713:B4V02 RS03955
gene id: 172713:B4V02_RS03955
uniprot id: A0A222WJE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

172713:B4V02 RS06955
gene id: 172713:B4V02_RS06955
uniprot id: A0A222WJR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

172713:B4V02 RS24715
gene id: 172713:B4V02_RS24715
uniprot id: A0A222WSQ8
names: Similarity
messages: Belongs to the MotB family.

172713:B4V02 RS15150
gene id: 172713:B4V02_RS15150
uniprot id: A0A222WQ86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

172713:B4V02 RS09895
gene id: 172713:B4V02_RS09895
uniprot id: A0A222WKG0
names: Similarity
messages: Belongs to the Fur family.

172713:B4V02 RS07910
gene id: 172713:B4V02_RS07910
uniprot id: A0A222WKG3
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

172713:B4V02 RS25075
gene id: 172713:B4V02_RS25075
uniprot id: A0A222WU93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

172713:B4V02 RS09370
gene id: 172713:B4V02_RS09370
uniprot id: A0A222WLI0
names: Similarity
messages: Belongs to the UPF0473 family.

172713:B4V02 RS03535
gene id: 172713:B4V02_RS03535
uniprot id: A0A222WIB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

172713:B4V02 RS10015
gene id: 172713:B4V02_RS10015
uniprot id: A0A222WMH0
names: Similarity
messages: Belongs to the asp23 family.

172713:B4V02 RS03730
gene id: 172713:B4V02_RS03730
uniprot id: A0A222WJC1
names: Similarity
messages: Belongs to the ThiD family.

172713:B4V02 RS08705
gene id: 172713:B4V02_RS08705
uniprot id: A0A222WKW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS15390
gene id: 172713:B4V02_RS15390
uniprot id: A0A222WND6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

172713:B4V02 RS15205
gene id: 172713:B4V02_RS15205
uniprot id: A0A222WQ98
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

172713:B4V02 RS09305
gene id: 172713:B4V02_RS09305
uniprot id: A0A222WLG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS02155
gene id: 172713:B4V02_RS02155
uniprot id: A0A222WGV9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

172713:B4V02 RS04625
gene id: 172713:B4V02_RS04625
uniprot id: A0A222WJQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

172713:B4V02 RS24855
gene id: 172713:B4V02_RS24855
uniprot id: A0A222WUX6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

172713:B4V02 RS02885
gene id: 172713:B4V02_RS02885
uniprot id: A0A222WIX9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

172713:B4V02 RS20230
gene id: 172713:B4V02_RS20230
uniprot id: A0A222WSY4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

172713:B4V02 RS02805
gene id: 172713:B4V02_RS02805
uniprot id: A0A222WHP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

172713:B4V02 RS24160
gene id: 172713:B4V02_RS24160
uniprot id: A0A222WUA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS18870
gene id: 172713:B4V02_RS18870
uniprot id: A0A222WPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS01250
gene id: 172713:B4V02_RS01250
uniprot id: A0A222WGD0
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS15540
gene id: 172713:B4V02_RS15540
uniprot id: A0A222WNF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

172713:B4V02 RS19375
gene id: 172713:B4V02_RS19375
uniprot id: A0A222WS02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

172713:B4V02 RS03005
gene id: 172713:B4V02_RS03005
uniprot id: A0A222WHT6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

172713:B4V02 RS18990
gene id: 172713:B4V02_RS18990
uniprot id: A0A222WVC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

172713:B4V02 RS14400
gene id: 172713:B4V02_RS14400
uniprot id: A0A222WP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS11455
gene id: 172713:B4V02_RS11455
uniprot id: A0A222WLC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

172713:B4V02 RS02865
gene id: 172713:B4V02_RS02865
uniprot id: A0A222WH70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

172713:B4V02 RS01900
gene id: 172713:B4V02_RS01900
uniprot id: A0A222WGR2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

172713:B4V02 RS25200
gene id: 172713:B4V02_RS25200
uniprot id: A0A222WT80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

172713:B4V02 RS11310
gene id: 172713:B4V02_RS11310
uniprot id: A0A222WNC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

172713:B4V02 RS14140
gene id: 172713:B4V02_RS14140
uniprot id: A0A222WMM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

172713:B4V02 RS24845
gene id: 172713:B4V02_RS24845
uniprot id: A0A222WUL5
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS24690
gene id: 172713:B4V02_RS24690
uniprot id: A0A222WUK1
names: Similarity
messages: Belongs to the peptidase C40 family.

172713:B4V02 RS21095
gene id: 172713:B4V02_RS21095
uniprot id: A0A222WSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS01475
gene id: 172713:B4V02_RS01475
uniprot id: A0A222WGI6
names: Similarity
messages: Belongs to the pirin family.

172713:B4V02 RS09485
gene id: 172713:B4V02_RS09485
uniprot id: A0A222WM83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

172713:B4V02 RS17155
gene id: 172713:B4V02_RS17155
uniprot id: A0A222WR46
names: Similarity
messages: Belongs to the manganese catalase family.

172713:B4V02 RS03020
gene id: 172713:B4V02_RS03020
uniprot id: A0A222WIC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

172713:B4V02 RS01435
gene id: 172713:B4V02_RS01435
uniprot id: A0A222WI60
names: Similarity
messages: Belongs to the Fur family.

172713:B4V02 RS18970
gene id: 172713:B4V02_RS18970
uniprot id: A0A222WRY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

172713:B4V02 RS19020
gene id: 172713:B4V02_RS19020
uniprot id: A0A222WSH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

172713:B4V02 RS16350
gene id: 172713:B4V02_RS16350
uniprot id: A0A222WQ67
names: Subcellular Location Annotation
messages: Cytoplasm

172713:B4V02 RS16190
gene id: 172713:B4V02_RS16190
uniprot id: A0A222WNL0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

172713:B4V02 RS24265
gene id: 172713:B4V02_RS24265
uniprot id: A0A222WSF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

172713:B4V02 RS02230
gene id: 172713:B4V02_RS02230
uniprot id: A0A222WIK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

172713:B4V02 RS02955
gene id: 172713:B4V02_RS02955
uniprot id: A0A222WHS4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

172713:B4V02 RS21370
gene id: 172713:B4V02_RS21370
uniprot id: A0A222WSX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS08990
gene id: 172713:B4V02_RS08990
uniprot id: A0A222WLE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

172713:B4V02 RS21375
gene id: 172713:B4V02_RS21375
uniprot id: A0A222WTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

172713:B4V02 RS02395
gene id: 172713:B4V02_RS02395
uniprot id: A0A222WHY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

172713:B4V02 RS02045
gene id: 172713:B4V02_RS02045
uniprot id: A0A222WHI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

172713:B4V02 RS12395
gene id: 172713:B4V02_RS12395
uniprot id: A0A222WNP2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

172713:B4V02 RS11355
gene id: 172713:B4V02_RS11355
uniprot id: A0A222WL72
names: Similarity
messages: Belongs to the FPG family.

172713:B4V02 RS17800
gene id: 172713:B4V02_RS17800
uniprot id: A0A222WRG5
names: Subcellular Location Annotation
messages: Membrane

172713:B4V02 RS10320
gene id: 172713:B4V02_RS10320
uniprot id: A0A222WMT3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

172713:B4V02 RS15155
gene id: 172713:B4V02_RS15155
uniprot id: A0A222WPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

172713:B4V02 RS08815
gene id: 172713:B4V02_RS08815
uniprot id: A0A222WKZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

172713:B4V02 RS23515
gene id: 172713:B4V02_RS23515
uniprot id: A0A222WS51
names: Subcellular Location Annotation
messages: Cytoplasm

172713:B4V02 RS15340
gene id: 172713:B4V02_RS15340
uniprot id: A0A222WN51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

172713:B4V02 RS01445
gene id: 172713:B4V02_RS01445
uniprot id: A0A222WHU5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

172713:B4V02 RS02890
gene id: 172713:B4V02_RS02890
uniprot id: A0A222WI85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

172713:B4V02 RS06550
gene id: 172713:B4V02_RS06550
uniprot id: A0A222WKN2
names: Similarity
messages: Belongs to the UPF0473 family.