1715806:AOB57 RS07020
gene id: 1715806:AOB57_RS07020
uniprot id: A0A660HRZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

1715806:AOB57 RS07360
gene id: 1715806:AOB57_RS07360
uniprot id: A0A660HS53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

1715806:AOB57 RS11420
gene id: 1715806:AOB57_RS11420
uniprot id: A0A660HTS2
names: Similarity
messages: Belongs to the peptidase C56 family.

1715806:AOB57 RS11780
gene id: 1715806:AOB57_RS11780
uniprot id: A0A660HVU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1715806:AOB57 RS01110
gene id: 1715806:AOB57_RS01110
uniprot id: A0A660HP10
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS03955
gene id: 1715806:AOB57_RS03955
uniprot id: A0A660HQB8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1715806:AOB57 RS06715
gene id: 1715806:AOB57_RS06715
uniprot id: A0A660HS33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

1715806:AOB57 RS14265
gene id: 1715806:AOB57_RS14265
uniprot id: A0A660HV89
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS05350
gene id: 1715806:AOB57_RS05350
uniprot id: A0A660HR27
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1715806:AOB57 RS08820
gene id: 1715806:AOB57_RS08820
uniprot id: A0A660HSQ1
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS01710
gene id: 1715806:AOB57_RS01710
uniprot id: A0A660HP77
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1715806:AOB57 RS10940
gene id: 1715806:AOB57_RS10940
uniprot id: A0A660HU48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS10505
gene id: 1715806:AOB57_RS10505
uniprot id: A0A660HTX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1715806:AOB57 RS09970
gene id: 1715806:AOB57_RS09970
uniprot id: A0A660HT25
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1715806:AOB57 RS12010
gene id: 1715806:AOB57_RS12010
uniprot id: A0A660HUN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1715806:AOB57 RS09295
gene id: 1715806:AOB57_RS09295
uniprot id: A0A660HSV3
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1715806:AOB57 RS01375
gene id: 1715806:AOB57_RS01375
uniprot id: A0A660HPQ4
names: Similarity
messages: Belongs to the complex I subunit 3 family.

1715806:AOB57 RS11445
gene id: 1715806:AOB57_RS11445
uniprot id: A0A660HU03
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'-methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'-deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: SAH is a product of SAM methyltransferases and is known to be a feedback inhibitor of these enzymes. As a result of this inhibition, organisms have evolved efficient enzymes to metabolize SAH via different pathways. The pathway found in methanogens differs from the canonical pathway, it uses the deamination of S-adenosyl-L-homocysteine to form S-inosyl-L-homocysteine for the regeneration of SAM from S-adenosyl-L-homocysteine. 5'-deoxyadenosine is a radical SAM enzyme reaction product which strongly inhibits radical SAM enzymes. A pathway for removing this product must be present in methanogens where the MTA/SAH nucleosidase which normally metabolizes this compound is absent.

1715806:AOB57 RS08625
gene id: 1715806:AOB57_RS08625
uniprot id: A0A660HSY5
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1715806:AOB57 RS09865
gene id: 1715806:AOB57_RS09865
uniprot id: A0A660HT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS06010
gene id: 1715806:AOB57_RS06010
uniprot id: A0A660HR94
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

1715806:AOB57 RS12720
gene id: 1715806:AOB57_RS12720
uniprot id: A0A660HV02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS08460
gene id: 1715806:AOB57_RS08460
uniprot id: A0A660HSF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

1715806:AOB57 RS06775
gene id: 1715806:AOB57_RS06775
uniprot id: A0A660HRR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1715806:AOB57 RS10640
gene id: 1715806:AOB57_RS10640
uniprot id: A0A660HTZ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1715806:AOB57 RS09075
gene id: 1715806:AOB57_RS09075
uniprot id: A0A660HSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

1715806:AOB57 RS00340
gene id: 1715806:AOB57_RS00340
uniprot id: A0A660HNL9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

1715806:AOB57 RS02385
gene id: 1715806:AOB57_RS02385
uniprot id: A0A660HPJ1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1715806:AOB57 RS06245
gene id: 1715806:AOB57_RS06245
uniprot id: A0A660HS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1715806:AOB57 RS05680
gene id: 1715806:AOB57_RS05680
uniprot id: A0A660HRQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1715806:AOB57 RS09470
gene id: 1715806:AOB57_RS09470
uniprot id: A0A660HSX6
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS04740
gene id: 1715806:AOB57_RS04740
uniprot id: A0A660HQU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1715806:AOB57 RS07280
gene id: 1715806:AOB57_RS07280
uniprot id: A0A660HS00
names: Subunit
messages: MCR is composed of three subunits: alpha, beta, and gamma. The function of proteins C and D is not known.

1715806:AOB57 RS04745
gene id: 1715806:AOB57_RS04745
uniprot id: A0A660HQS4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1715806:AOB57 RS08300
gene id: 1715806:AOB57_RS08300
uniprot id: A0A660HSH5
names: Similarity
messages: Belongs to the UPF0201 family.

1715806:AOB57 RS06040
gene id: 1715806:AOB57_RS06040
uniprot id: A0A660HRB7
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS08050
gene id: 1715806:AOB57_RS08050
uniprot id: A0A660HSC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1715806:AOB57 RS10735
gene id: 1715806:AOB57_RS10735
uniprot id: A0A660HTD3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1715806:AOB57 RS09465
gene id: 1715806:AOB57_RS09465
uniprot id: A0A660HSX8
names: Similarity
messages: Belongs to the UPF0107 family.

1715806:AOB57 RS12580
gene id: 1715806:AOB57_RS12580
uniprot id: A0A660HUI3
names: Similarity
messages: Belongs to the UPF0210 family.

1715806:AOB57 RS00790
gene id: 1715806:AOB57_RS00790
uniprot id: A0A660HVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1715806:AOB57 RS05390
gene id: 1715806:AOB57_RS05390
uniprot id: A0A660HR06
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1715806:AOB57 RS08845
gene id: 1715806:AOB57_RS08845
uniprot id: A0A660HSN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

1715806:AOB57 RS00960
gene id: 1715806:AOB57_RS00960
uniprot id: A0A660HNW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1715806:AOB57 RS08720
gene id: 1715806:AOB57_RS08720
uniprot id: A0A660HTT4
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1715806:AOB57 RS01325
gene id: 1715806:AOB57_RS01325
uniprot id: A0A660HP14
names: Function
messages: Part of a potassium transport system.

1715806:AOB57 RS10885
gene id: 1715806:AOB57_RS10885
uniprot id: A0A660HU38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

1715806:AOB57 RS08905
gene id: 1715806:AOB57_RS08905
uniprot id: A0A660HSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
messages: Cytoplasm

1715806:AOB57 RS12260
gene id: 1715806:AOB57_RS12260
uniprot id: A0A660HUC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1715806:AOB57 RS03790
gene id: 1715806:AOB57_RS03790
uniprot id: A0A660HQ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1715806:AOB57 RS02230
gene id: 1715806:AOB57_RS02230
uniprot id: A0A660HPX5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS10135
gene id: 1715806:AOB57_RS10135
uniprot id: A0A660HVR0
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS11815
gene id: 1715806:AOB57_RS11815
uniprot id: A0A660HVA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1715806:AOB57 RS08450
gene id: 1715806:AOB57_RS08450
uniprot id: A0A660HSH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1715806:AOB57 RS10635
gene id: 1715806:AOB57_RS10635
uniprot id: A0A660HUQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

1715806:AOB57 RS08830
gene id: 1715806:AOB57_RS08830
uniprot id: A0A660HSP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

1715806:AOB57 RS01885
gene id: 1715806:AOB57_RS01885
uniprot id: A0A660HVW0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine synthase family. Cysteate synthase subfamily.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.

1715806:AOB57 RS01785
gene id: 1715806:AOB57_RS01785
uniprot id: A0A660HP88
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1715806:AOB57 RS02060
gene id: 1715806:AOB57_RS02060
uniprot id: A0A660HPK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1715806:AOB57 RS03600
gene id: 1715806:AOB57_RS03600
uniprot id: A0A7K4AV42
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS07270
gene id: 1715806:AOB57_RS07270
uniprot id: A0A660HSG9
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase beta subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

1715806:AOB57 RS06975
gene id: 1715806:AOB57_RS06975
uniprot id: A0A660HRW6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1715806:AOB57 RS07340
gene id: 1715806:AOB57_RS07340
uniprot id: A0A660HSD1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1715806:AOB57 RS01760
gene id: 1715806:AOB57_RS01760
uniprot id: A0A660HPW0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: In Archaea the pyridoxal phosphate cofactor is not covalently bound to Lys but ligated by other amino acids.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1715806:AOB57 RS06910
gene id: 1715806:AOB57_RS06910
uniprot id: A0A660HRW9
names: Similarity
messages: Belongs to the HdrC family.

1715806:AOB57 RS06540
gene id: 1715806:AOB57_RS06540
uniprot id: A0A660HRN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

1715806:AOB57 RS04070
gene id: 1715806:AOB57_RS04070
uniprot id: A0A660HQE3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1715806:AOB57 RS10565
gene id: 1715806:AOB57_RS10565
uniprot id: A0A660HTA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS08200
gene id: 1715806:AOB57_RS08200
uniprot id: A0A660HSE1
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

1715806:AOB57 RS09160
gene id: 1715806:AOB57_RS09160
uniprot id: A0A660HST0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS11720
gene id: 1715806:AOB57_RS11720
uniprot id: A0A660HXS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS09355
gene id: 1715806:AOB57_RS09355
uniprot id: A0A660HSV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrB family.
messages: Cell membrane
messages: Membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

1715806:AOB57 RS11680
gene id: 1715806:AOB57_RS11680
uniprot id: A0A660HW22
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1715806:AOB57 RS13875
gene id: 1715806:AOB57_RS13875
uniprot id: A0A660HV65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 2 family.
messages: Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1715806:AOB57 RS09510
gene id: 1715806:AOB57_RS09510
uniprot id: A0A7K4AYQ2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS13060
gene id: 1715806:AOB57_RS13060
uniprot id: A0A660HVZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1715806:AOB57 RS05135
gene id: 1715806:AOB57_RS05135
uniprot id: A0A660HQW8
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

1715806:AOB57 RS04400
gene id: 1715806:AOB57_RS04400
uniprot id: A0A660HQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1715806:AOB57 RS12305
gene id: 1715806:AOB57_RS12305
uniprot id: A0A660HVY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1715806:AOB57 RS07705
gene id: 1715806:AOB57_RS07705
uniprot id: A0A660HS38
names: Function
names: Similarity
messages: Belongs to the MfnB family.
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

1715806:AOB57 RS10800
gene id: 1715806:AOB57_RS10800
uniprot id: A0A660HVR8
names: Similarity
messages: Belongs to the FBPase class 2 family.

1715806:AOB57 RS07330
gene id: 1715806:AOB57_RS07330
uniprot id: A0A660HS20
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1715806:AOB57 RS03110
gene id: 1715806:AOB57_RS03110
uniprot id: A0A660HQ13
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

1715806:AOB57 RS13140
gene id: 1715806:AOB57_RS13140
uniprot id: A0A660HUR0
names: Similarity
messages: Belongs to the TrpF family.

1715806:AOB57 RS01145
gene id: 1715806:AOB57_RS01145
uniprot id: A0A660HNZ6
names: Similarity
messages: Belongs to the UPF0111 family.

1715806:AOB57 RS01420
gene id: 1715806:AOB57_RS01420
uniprot id: A0A660HP63
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS12705
gene id: 1715806:AOB57_RS12705
uniprot id: A0A660HUJ6
names: Similarity
messages: Belongs to the CutA family.

1715806:AOB57 RS06075
gene id: 1715806:AOB57_RS06075
uniprot id: A0A660HRE2
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS10170
gene id: 1715806:AOB57_RS10170
uniprot id: A0A660HT70
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS12670
gene id: 1715806:AOB57_RS12670
uniprot id: A0A660HUE5
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

1715806:AOB57 RS05015
gene id: 1715806:AOB57_RS05015
uniprot id: A0A660HQU8
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

1715806:AOB57 RS08735
gene id: 1715806:AOB57_RS08735
uniprot id: A0A660HSM2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1715806:AOB57 RS05590
gene id: 1715806:AOB57_RS05590
uniprot id: A0A660HR83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Monomer and homodimer.

1715806:AOB57 RS12790
gene id: 1715806:AOB57_RS12790
uniprot id: A0A660HUJ1
names: Similarity
messages: Belongs to the oxoprolinase family.

1715806:AOB57 RS08525
gene id: 1715806:AOB57_RS08525
uniprot id: A0A660HSG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS02725
gene id: 1715806:AOB57_RS02725
uniprot id: A0A660HPQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1715806:AOB57 RS05110
gene id: 1715806:AOB57_RS05110
uniprot id: A0A660HQU6
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS10615
gene id: 1715806:AOB57_RS10615
uniprot id: A0A660HTB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1715806:AOB57 RS05195
gene id: 1715806:AOB57_RS05195
uniprot id: A0A660HRH0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1715806:AOB57 RS01330
gene id: 1715806:AOB57_RS01330
uniprot id: A0A660HP26
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS06150
gene id: 1715806:AOB57_RS06150
uniprot id: A0A660HRD4
names: Similarity
messages: Belongs to the FrhG family.

1715806:AOB57 RS00835
gene id: 1715806:AOB57_RS00835
uniprot id: A0A660HNV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1715806:AOB57 RS09300
gene id: 1715806:AOB57_RS09300
uniprot id: A0A660HSU6
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS09965
gene id: 1715806:AOB57_RS09965
uniprot id: A0A660HTM7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1715806:AOB57 RS05190
gene id: 1715806:AOB57_RS05190
uniprot id: A0A660HXA5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1715806:AOB57 RS06435
gene id: 1715806:AOB57_RS06435
uniprot id: A0A660HRL4
names: Domain
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Contains a predicted C4 metal binding domain at the N-terminus, which could be a zinc finger DNA binding domain.
messages: Involved in DNA damage repair.

1715806:AOB57 RS06595
gene id: 1715806:AOB57_RS06595
uniprot id: A0A660HRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1715806:AOB57 RS07765
gene id: 1715806:AOB57_RS07765
uniprot id: A0A660HXG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

1715806:AOB57 RS11700
gene id: 1715806:AOB57_RS11700
uniprot id: A0A660HUH9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1715806:AOB57 RS05940
gene id: 1715806:AOB57_RS05940
uniprot id: A0A660HVH8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS00765
gene id: 1715806:AOB57_RS00765
uniprot id: A0A660HNU2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1715806:AOB57 RS10780
gene id: 1715806:AOB57_RS10780
uniprot id: A0A660HTF4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1715806:AOB57 RS07005
gene id: 1715806:AOB57_RS07005
uniprot id: A0A660HRT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

1715806:AOB57 RS00645
gene id: 1715806:AOB57_RS00645
uniprot id: A0A660HNW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS00370
gene id: 1715806:AOB57_RS00370
uniprot id: A0A660HNL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

1715806:AOB57 RS01165
gene id: 1715806:AOB57_RS01165
uniprot id: A0A660HNZ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1715806:AOB57 RS06865
gene id: 1715806:AOB57_RS06865
uniprot id: A0A660HRU2
names: Similarity
messages: Belongs to the glutamate synthase family.

1715806:AOB57 RS01130
gene id: 1715806:AOB57_RS01130
uniprot id: A0A660HV87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1715806:AOB57 RS03675
gene id: 1715806:AOB57_RS03675
uniprot id: A0A660HQB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1715806:AOB57 RS00755
gene id: 1715806:AOB57_RS00755
uniprot id: A0A660HNU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1715806:AOB57 RS03655
gene id: 1715806:AOB57_RS03655
uniprot id: A0A660HQ74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1715806:AOB57 RS02410
gene id: 1715806:AOB57_RS02410
uniprot id: A0A660HPK4
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1715806:AOB57 RS03170
gene id: 1715806:AOB57_RS03170
uniprot id: A0A660HPX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CbiX family. CbiXS subfamily.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni-sirohydrochlorin.
messages: Homotetramer; dimer of dimers.

1715806:AOB57 RS08395
gene id: 1715806:AOB57_RS08395
uniprot id: A0A660HSU9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS05210
gene id: 1715806:AOB57_RS05210
uniprot id: A0A660HQX6
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

1715806:AOB57 RS03315
gene id: 1715806:AOB57_RS03315
uniprot id: A0A660HPY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

1715806:AOB57 RS07735
gene id: 1715806:AOB57_RS07735
uniprot id: A0A660HS86
names: Function
names: Similarity
messages: Belongs to the MTD family.
messages: Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.

1715806:AOB57 RS10550
gene id: 1715806:AOB57_RS10550
uniprot id: A0A660HTD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1715806:AOB57 RS00470
gene id: 1715806:AOB57_RS00470
uniprot id: A0A660HPB1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS03700
gene id: 1715806:AOB57_RS03700
uniprot id: A0A660HQS1
names: Similarity
messages: Belongs to the UPF0285 family.

1715806:AOB57 RS00710
gene id: 1715806:AOB57_RS00710
uniprot id: A0A660HNT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS08315
gene id: 1715806:AOB57_RS08315
uniprot id: A0A660HWA8
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.

1715806:AOB57 RS07455
gene id: 1715806:AOB57_RS07455
uniprot id: A0A660HS27
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1715806:AOB57 RS07085
gene id: 1715806:AOB57_RS07085
uniprot id: A0A660HRY3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS09340
gene id: 1715806:AOB57_RS09340
uniprot id: A0A660HU30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

1715806:AOB57 RS00165
gene id: 1715806:AOB57_RS00165
uniprot id: A0A660HP64
names: Similarity
messages: Belongs to the LOR family.

1715806:AOB57 RS06850
gene id: 1715806:AOB57_RS06850
uniprot id: A0A660HRN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1715806:AOB57 RS14295
gene id: 1715806:AOB57_RS14295
uniprot id: A0A660HVS6
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS10180
gene id: 1715806:AOB57_RS10180
uniprot id: A0A660HT50
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1715806:AOB57 RS11355
gene id: 1715806:AOB57_RS11355
uniprot id: A0A660HUB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS11195
gene id: 1715806:AOB57_RS11195
uniprot id: A0A660HTU9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1715806:AOB57 RS13870
gene id: 1715806:AOB57_RS13870
uniprot id: A0A660HV29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1715806:AOB57 RS05655
gene id: 1715806:AOB57_RS05655
uniprot id: A0A660HR93
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

1715806:AOB57 RS07980
gene id: 1715806:AOB57_RS07980
uniprot id: A0A660HSB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1715806:AOB57 RS10500
gene id: 1715806:AOB57_RS10500
uniprot id: A0A660HTC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1715806:AOB57 RS04385
gene id: 1715806:AOB57_RS04385
uniprot id: A0A660HQK7
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1715806:AOB57 RS06660
gene id: 1715806:AOB57_RS06660
uniprot id: A0A660HRP4
names: Similarity
messages: Belongs to the UPF0288 family.

1715806:AOB57 RS04075
gene id: 1715806:AOB57_RS04075
uniprot id: A0A660HQE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1715806:AOB57 RS03845
gene id: 1715806:AOB57_RS03845
uniprot id: A0A660HQ70
names: Similarity
messages: Belongs to the UPF0284 family.

1715806:AOB57 RS09255
gene id: 1715806:AOB57_RS09255
uniprot id: A0A660HSR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1715806:AOB57 RS00655
gene id: 1715806:AOB57_RS00655
uniprot id: A0A7K4AWN1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS13695
gene id: 1715806:AOB57_RS13695
uniprot id: A0A660HWC7
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

1715806:AOB57 RS09150
gene id: 1715806:AOB57_RS09150
uniprot id: A0A660HU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS03835
gene id: 1715806:AOB57_RS03835
uniprot id: A0A660HQQ4
names: Similarity
messages: Belongs to the ZPR1 family.

1715806:AOB57 RS10750
gene id: 1715806:AOB57_RS10750
uniprot id: A0A660HTJ1
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1715806:AOB57 RS11820
gene id: 1715806:AOB57_RS11820
uniprot id: A0A660HUJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1715806:AOB57 RS05185
gene id: 1715806:AOB57_RS05185
uniprot id: A0A660HQY1
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS10545
gene id: 1715806:AOB57_RS10545
uniprot id: A0A660HTD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

1715806:AOB57 RS08580
gene id: 1715806:AOB57_RS08580
uniprot id: A0A660HSL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

1715806:AOB57 RS09920
gene id: 1715806:AOB57_RS09920
uniprot id: A0A660HT92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS09585
gene id: 1715806:AOB57_RS09585
uniprot id: A0A660HSZ1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1715806:AOB57 RS05325
gene id: 1715806:AOB57_RS05325
uniprot id: A0A660HQZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS08100
gene id: 1715806:AOB57_RS08100
uniprot id: A0A660HSD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1715806:AOB57 RS08330
gene id: 1715806:AOB57_RS08330
uniprot id: A0A660HST8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR).
messages: Cytoplasm
messages: Homotetramer.

1715806:AOB57 RS14180
gene id: 1715806:AOB57_RS14180
uniprot id: A0A660HVC3
names: Similarity
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.

1715806:AOB57 RS03650
gene id: 1715806:AOB57_RS03650
uniprot id: A0A660HQ73
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS04695
gene id: 1715806:AOB57_RS04695
uniprot id: A0A660HVN4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1715806:AOB57 RS09145
gene id: 1715806:AOB57_RS09145
uniprot id: A0A660HSU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS07400
gene id: 1715806:AOB57_RS07400
uniprot id: A0A660HSD9
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

1715806:AOB57 RS10775
gene id: 1715806:AOB57_RS10775
uniprot id: A0A660HU18
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1715806:AOB57 RS10865
gene id: 1715806:AOB57_RS10865
uniprot id: A0A660HUU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1715806:AOB57 RS09575
gene id: 1715806:AOB57_RS09575
uniprot id: A0A660HTH7
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1715806:AOB57 RS12075
gene id: 1715806:AOB57_RS12075
uniprot id: A0A660HUP8
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1715806:AOB57 RS06210
gene id: 1715806:AOB57_RS06210
uniprot id: A0A660HRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1715806:AOB57 RS05980
gene id: 1715806:AOB57_RS05980
uniprot id: A0A660HRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1715806:AOB57 RS09140
gene id: 1715806:AOB57_RS09140
uniprot id: A0A660HVS2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1715806:AOB57 RS11480
gene id: 1715806:AOB57_RS11480
uniprot id: A0A660HTT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1715806:AOB57 RS10965
gene id: 1715806:AOB57_RS10965
uniprot id: A0A660HTN5
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1715806:AOB57 RS07985
gene id: 1715806:AOB57_RS07985
uniprot id: A0A660HSP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS04530
gene id: 1715806:AOB57_RS04530
uniprot id: A0A660HVD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS03660
gene id: 1715806:AOB57_RS03660
uniprot id: A0A660HQM4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1715806:AOB57 RS12725
gene id: 1715806:AOB57_RS12725
uniprot id: A0A660HUI0
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS11010
gene id: 1715806:AOB57_RS11010
uniprot id: A0A660HTH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1715806:AOB57 RS10000
gene id: 1715806:AOB57_RS10000
uniprot id: A0A660HT67
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS04415
gene id: 1715806:AOB57_RS04415
uniprot id: A0A660HQL7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1715806:AOB57 RS06090
gene id: 1715806:AOB57_RS06090
uniprot id: A0A660HRD7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1715806:AOB57 RS14220
gene id: 1715806:AOB57_RS14220
uniprot id: A0A660HWU2
names: Similarity
messages: Belongs to the AHA1 family.

1715806:AOB57 RS11170
gene id: 1715806:AOB57_RS11170
uniprot id: A0A660HTN7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1715806:AOB57 RS10560
gene id: 1715806:AOB57_RS10560
uniprot id: A0A660HTB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1715806:AOB57 RS07060
gene id: 1715806:AOB57_RS07060
uniprot id: A0A660HVE9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1715806:AOB57 RS06025
gene id: 1715806:AOB57_RS06025
uniprot id: A0A660HRW8
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1715806:AOB57 RS04545
gene id: 1715806:AOB57_RS04545
uniprot id: A0A660HQR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS06915
gene id: 1715806:AOB57_RS06915
uniprot id: A0A660HRV1
names: Similarity
messages: Belongs to the HdrB family.

1715806:AOB57 RS12455
gene id: 1715806:AOB57_RS12455
uniprot id: A0A660HUG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

1715806:AOB57 RS09735
gene id: 1715806:AOB57_RS09735
uniprot id: A0A660HSY1
names: Similarity
messages: Belongs to the tRNA(His) guanylyltransferase family.

1715806:AOB57 RS06190
gene id: 1715806:AOB57_RS06190
uniprot id: A0A660HRZ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

1715806:AOB57 RS03730
gene id: 1715806:AOB57_RS03730
uniprot id: A0A660HQ47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CdhC family.
messages: Binds 1 [Ni-Fe-S] cluster.
messages: Monomer. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex).

1715806:AOB57 RS10255
gene id: 1715806:AOB57_RS10255
uniprot id: A0A660HTA2
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1715806:AOB57 RS05130
gene id: 1715806:AOB57_RS05130
uniprot id: A0A660HQY5
names: Similarity
messages: Belongs to the LarC family.

1715806:AOB57 RS01775
gene id: 1715806:AOB57_RS01775
uniprot id: A0A660HPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1715806:AOB57 RS13215
gene id: 1715806:AOB57_RS13215
uniprot id: A0A660HUN0
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS03910
gene id: 1715806:AOB57_RS03910
uniprot id: A0A660HQA9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.

1715806:AOB57 RS03280
gene id: 1715806:AOB57_RS03280
uniprot id: A0A660HVL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

1715806:AOB57 RS05100
gene id: 1715806:AOB57_RS05100
uniprot id: A0A660HRA2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

1715806:AOB57 RS02390
gene id: 1715806:AOB57_RS02390
uniprot id: A0A660HQ48
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1715806:AOB57 RS01355
gene id: 1715806:AOB57_RS01355
uniprot id: A0A660HVC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofH family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

1715806:AOB57 RS05530
gene id: 1715806:AOB57_RS05530
uniprot id: A0A660HR74
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1715806:AOB57 RS00940
gene id: 1715806:AOB57_RS00940
uniprot id: A0A660HNX5
names: Similarity
messages: Belongs to the catalase family.

1715806:AOB57 RS01685
gene id: 1715806:AOB57_RS01685
uniprot id: A0A660HP95
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

1715806:AOB57 RS12100
gene id: 1715806:AOB57_RS12100
uniprot id: A0A660HU87
names: Similarity
messages: Belongs to the TPP enzyme family.

1715806:AOB57 RS07225
gene id: 1715806:AOB57_RS07225
uniprot id: A0A660HRZ9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1715806:AOB57 RS13585
gene id: 1715806:AOB57_RS13585
uniprot id: A0A660HV26
names: Similarity
messages: Belongs to the peptidase C56 family.

1715806:AOB57 RS01940
gene id: 1715806:AOB57_RS01940
uniprot id: A0A660HPI2
names: Similarity
messages: Belongs to the GARS family.

1715806:AOB57 RS01275
gene id: 1715806:AOB57_RS01275
uniprot id: A0A660HPN7
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1715806:AOB57 RS07385
gene id: 1715806:AOB57_RS07385
uniprot id: A0A660HSI7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1715806:AOB57 RS07035
gene id: 1715806:AOB57_RS07035
uniprot id: A0A660HRT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

1715806:AOB57 RS03555
gene id: 1715806:AOB57_RS03555
uniprot id: A0A660HQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1715806:AOB57 RS02380
gene id: 1715806:AOB57_RS02380
uniprot id: A0A660HPL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS10320
gene id: 1715806:AOB57_RS10320
uniprot id: A0A660HTU3
names: Similarity
messages: Belongs to the NAD synthetase family.

1715806:AOB57 RS09005
gene id: 1715806:AOB57_RS09005
uniprot id: A0A660HSW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1715806:AOB57 RS03085
gene id: 1715806:AOB57_RS03085
uniprot id: A0A660HPX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS09580
gene id: 1715806:AOB57_RS09580
uniprot id: A0A660HSZ3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1715806:AOB57 RS06170
gene id: 1715806:AOB57_RS06170
uniprot id: A0A660HRI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS06720
gene id: 1715806:AOB57_RS06720
uniprot id: A0A660HRN3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1715806:AOB57 RS06970
gene id: 1715806:AOB57_RS06970
uniprot id: A0A660HRV9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1715806:AOB57 RS09690
gene id: 1715806:AOB57_RS09690
uniprot id: A0A660HXM1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1715806:AOB57 RS07615
gene id: 1715806:AOB57_RS07615
uniprot id: A0A660HS59
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1715806:AOB57 RS05120
gene id: 1715806:AOB57_RS05120
uniprot id: A0A660HQT0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS02570
gene id: 1715806:AOB57_RS02570
uniprot id: A0A660HPM4
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

1715806:AOB57 RS03275
gene id: 1715806:AOB57_RS03275
uniprot id: A0A660HVG9
names: Similarity
messages: Belongs to the UPF0179 family.

1715806:AOB57 RS10955
gene id: 1715806:AOB57_RS10955
uniprot id: A0A660HTS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

1715806:AOB57 RS01005
gene id: 1715806:AOB57_RS01005
uniprot id: A0A660HPJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1715806:AOB57 RS01010
gene id: 1715806:AOB57_RS01010
uniprot id: A0A660HNX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1715806:AOB57 RS01320
gene id: 1715806:AOB57_RS01320
uniprot id: A0A660HPP5
names: Function
messages: Part of a potassium transport system.

1715806:AOB57 RS06620
gene id: 1715806:AOB57_RS06620
uniprot id: A0A660HRL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

1715806:AOB57 RS03805
gene id: 1715806:AOB57_RS03805
uniprot id: A0A660HQA6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1715806:AOB57 RS11190
gene id: 1715806:AOB57_RS11190
uniprot id: A0A660HTW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1715806:AOB57 RS00465
gene id: 1715806:AOB57_RS00465
uniprot id: A0A660HNP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1715806:AOB57 RS10025
gene id: 1715806:AOB57_RS10025
uniprot id: A0A660HVV0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1715806:AOB57 RS10600
gene id: 1715806:AOB57_RS10600
uniprot id: A0A660HTE1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1715806:AOB57 RS03150
gene id: 1715806:AOB57_RS03150
uniprot id: A0A660HPX2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP, and cobyrinate or Ni-sirohydrochlorin, and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate and Ni-sirohydrochlorin are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1715806:AOB57 RS02545
gene id: 1715806:AOB57_RS02545
uniprot id: A0A660HPN6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1715806:AOB57 RS10525
gene id: 1715806:AOB57_RS10525
uniprot id: A0A660HTI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS06645
gene id: 1715806:AOB57_RS06645
uniprot id: A0A660HRK9
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS10740
gene id: 1715806:AOB57_RS10740
uniprot id: A0A660HTN2
names: Similarity
messages: Belongs to the HypD family.

1715806:AOB57 RS10630
gene id: 1715806:AOB57_RS10630
uniprot id: A0A660HTG6
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS01160
gene id: 1715806:AOB57_RS01160
uniprot id: A0A660HP03
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS05990
gene id: 1715806:AOB57_RS05990
uniprot id: A0A660HR77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SepCysS family.
messages: Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
messages: Homodimer. Interacts with SepRS.

1715806:AOB57 RS07640
gene id: 1715806:AOB57_RS07640
uniprot id: A0A7K4ATP0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS06330
gene id: 1715806:AOB57_RS06330
uniprot id: A0A660HRJ7
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS06455
gene id: 1715806:AOB57_RS06455
uniprot id: A0A660HRK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1715806:AOB57 RS07290
gene id: 1715806:AOB57_RS07290
uniprot id: A0A660HRY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase alpha subunit family.
messages: Binds 2 coenzyme F430 non-covalently per MCR complex. Coenzyme F430 is a yellow nickel porphinoid. Methyl-coenzyme-M reductase is activated when the enzyme-bound coenzyme F430 is reduced to the Ni(I) oxidation state.
messages: Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

1715806:AOB57 RS02660
gene id: 1715806:AOB57_RS02660
uniprot id: A0A660HPR0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1715806:AOB57 RS07335
gene id: 1715806:AOB57_RS07335
uniprot id: A0A660HS10
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1715806:AOB57 RS01310
gene id: 1715806:AOB57_RS01310
uniprot id: A0A660HP36
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1715806:AOB57 RS07960
gene id: 1715806:AOB57_RS07960
uniprot id: A0A660HSV1
names: Similarity
messages: Belongs to the FwdC/FmdC family.

1715806:AOB57 RS05480
gene id: 1715806:AOB57_RS05480
uniprot id: A0A660HR00
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1715806:AOB57 RS03345
gene id: 1715806:AOB57_RS03345
uniprot id: A0A660HPZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1715806:AOB57 RS09220
gene id: 1715806:AOB57_RS09220
uniprot id: A0A660HST9
names: Similarity
messages: Belongs to the peptidase M24B family.

1715806:AOB57 RS00870
gene id: 1715806:AOB57_RS00870
uniprot id: A0A660HPA5
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1715806:AOB57 RS07710
gene id: 1715806:AOB57_RS07710
uniprot id: A0A660HSA7
names: Similarity
messages: Belongs to the HisA/HisF family.

1715806:AOB57 RS07450
gene id: 1715806:AOB57_RS07450
uniprot id: A0A660HS36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1715806:AOB57 RS01600
gene id: 1715806:AOB57_RS01600
uniprot id: A0A660HP72
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1715806:AOB57 RS11005
gene id: 1715806:AOB57_RS11005
uniprot id: A0A660HTI6
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

1715806:AOB57 RS03525
gene id: 1715806:AOB57_RS03525
uniprot id: A0A660HQP3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1715806:AOB57 RS07365
gene id: 1715806:AOB57_RS07365
uniprot id: A0A660HS37
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

1715806:AOB57 RS03840
gene id: 1715806:AOB57_RS03840
uniprot id: A0A660HQ98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS11915
gene id: 1715806:AOB57_RS11915
uniprot id: A0A660HU51
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS02430
gene id: 1715806:AOB57_RS02430
uniprot id: A0A660HPL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1715806:AOB57 RS00010
gene id: 1715806:AOB57_RS00010
uniprot id: A0A660HVR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

1715806:AOB57 RS05055
gene id: 1715806:AOB57_RS05055
uniprot id: A0A660HQZ5
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

1715806:AOB57 RS07130
gene id: 1715806:AOB57_RS07130
uniprot id: A0A660HS14
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS04370
gene id: 1715806:AOB57_RS04370
uniprot id: A0A660HQK2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

1715806:AOB57 RS11975
gene id: 1715806:AOB57_RS11975
uniprot id: A0A660HU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS11095
gene id: 1715806:AOB57_RS11095
uniprot id: A0A660HU76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbohydrate kinase PfkC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
messages: Cytoplasm

1715806:AOB57 RS05355
gene id: 1715806:AOB57_RS05355
uniprot id: A0A660HR15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1715806:AOB57 RS09995
gene id: 1715806:AOB57_RS09995
uniprot id: A0A660HVY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1715806:AOB57 RS12490
gene id: 1715806:AOB57_RS12490
uniprot id: A0A660HUZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1715806:AOB57 RS02065
gene id: 1715806:AOB57_RS02065
uniprot id: A0A660HPG0
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.

1715806:AOB57 RS04960
gene id: 1715806:AOB57_RS04960
uniprot id: A0A660HQT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity.

1715806:AOB57 RS07015
gene id: 1715806:AOB57_RS07015
uniprot id: A0A660HRR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1715806:AOB57 RS07370
gene id: 1715806:AOB57_RS07370
uniprot id: A0A660HS42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1715806:AOB57 RS00200
gene id: 1715806:AOB57_RS00200
uniprot id: A0A660HNI5
names: Similarity
messages: Belongs to the LOR family.

1715806:AOB57 RS11045
gene id: 1715806:AOB57_RS11045
uniprot id: A0A660HTL1
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS13650
gene id: 1715806:AOB57_RS13650
uniprot id: A0A660HVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1715806:AOB57 RS10140
gene id: 1715806:AOB57_RS10140
uniprot id: A0A660HUF8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1715806:AOB57 RS00865
gene id: 1715806:AOB57_RS00865
uniprot id: A0A660HNU6
names: Function
messages: Probably involved in the biogenesis of the ribosome.

1715806:AOB57 RS03720
gene id: 1715806:AOB57_RS03720
uniprot id: A0A660HQN3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Ni-containing carbon monoxide dehydrogenase family.
messages: Binds 2 [Ni-4Fe-4S] clusters per heterotetramer.
messages: Binds 7 [4Fe-4S] clusters per heterotetramer.
messages: Cluster B is an all-cysteinyl-liganded 4Fe-4S cluster; cluster C is a mixed Ni-Fe-S cluster which is the active site of CO oxidation. Cluster D is also an all-cysteinyl-liganded 4Fe-4S cluster that bridges the two subunits of the CODH dimer. Contains two additional 4Fe-4S clusters, dubbed E and F, that probably transport electrons from ferredoxin to the B cluster.
messages: Heterotetramer of two alpha and two epsilon subunits. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta subunits with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.

1715806:AOB57 RS12365
gene id: 1715806:AOB57_RS12365
uniprot id: A0A7K4AXW5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS08700
gene id: 1715806:AOB57_RS08700
uniprot id: A0A660HVR2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP, and cobyrinate or Ni-sirohydrochlorin, and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate and Ni-sirohydrochlorin are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1715806:AOB57 RS02005
gene id: 1715806:AOB57_RS02005
uniprot id: A0A660HPJ3
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

1715806:AOB57 RS08465
gene id: 1715806:AOB57_RS08465
uniprot id: A0A660HSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1715806:AOB57 RS03300
gene id: 1715806:AOB57_RS03300
uniprot id: A0A660HQ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1715806:AOB57 RS07140
gene id: 1715806:AOB57_RS07140
uniprot id: A0A7K4ASG6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS02070
gene id: 1715806:AOB57_RS02070
uniprot id: A0A660HPG6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

1715806:AOB57 RS13945
gene id: 1715806:AOB57_RS13945
uniprot id: A0A660HWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

1715806:AOB57 RS11845
gene id: 1715806:AOB57_RS11845
uniprot id: A0A660HTY0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1715806:AOB57 RS06100
gene id: 1715806:AOB57_RS06100
uniprot id: A0A660HVQ7
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS11100
gene id: 1715806:AOB57_RS11100
uniprot id: A0A660HTM2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1715806:AOB57 RS11290
gene id: 1715806:AOB57_RS11290
uniprot id: A0A660HVR1
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1715806:AOB57 RS11165
gene id: 1715806:AOB57_RS11165
uniprot id: A0A660HTN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1715806:AOB57 RS12555
gene id: 1715806:AOB57_RS12555
uniprot id: A0A660HV00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS04785
gene id: 1715806:AOB57_RS04785
uniprot id: A0A660HQQ8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1715806:AOB57 RS08090
gene id: 1715806:AOB57_RS08090
uniprot id: A0A660HSX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1715806:AOB57 RS13025
gene id: 1715806:AOB57_RS13025
uniprot id: A0A660HUP3
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS02825
gene id: 1715806:AOB57_RS02825
uniprot id: A0A660HV79
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1715806:AOB57 RS01360
gene id: 1715806:AOB57_RS01360
uniprot id: A0A660HP44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

1715806:AOB57 RS05105
gene id: 1715806:AOB57_RS05105
uniprot id: A0A660HVJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS04915
gene id: 1715806:AOB57_RS04915
uniprot id: A0A660HQR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1715806:AOB57 RS03865
gene id: 1715806:AOB57_RS03865
uniprot id: A0A660HQB7
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

1715806:AOB57 RS09035
gene id: 1715806:AOB57_RS09035
uniprot id: A0A660HTY3
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS07405
gene id: 1715806:AOB57_RS07405
uniprot id: A0A660HS02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1715806:AOB57 RS08570
gene id: 1715806:AOB57_RS08570
uniprot id: A0A660HSH1
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1715806:AOB57 RS14145
gene id: 1715806:AOB57_RS14145
uniprot id: A0A660HV32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

1715806:AOB57 RS06695
gene id: 1715806:AOB57_RS06695
uniprot id: A0A7K4AXN2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS06565
gene id: 1715806:AOB57_RS06565
uniprot id: A0A660HS05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1715806:AOB57 RS04095
gene id: 1715806:AOB57_RS04095
uniprot id: A0A660HQI2
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

1715806:AOB57 RS02295
gene id: 1715806:AOB57_RS02295
uniprot id: A0A660HPI4
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS09395
gene id: 1715806:AOB57_RS09395
uniprot id: A0A660HTF5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1715806:AOB57 RS12255
gene id: 1715806:AOB57_RS12255
uniprot id: A0A660HUE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1715806:AOB57 RS08565
gene id: 1715806:AOB57_RS08565
uniprot id: A0A660HSX4
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

1715806:AOB57 RS05460
gene id: 1715806:AOB57_RS05460
uniprot id: A0A660HQY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1715806:AOB57 RS08575
gene id: 1715806:AOB57_RS08575
uniprot id: A0A660HSP4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1715806:AOB57 RS09450
gene id: 1715806:AOB57_RS09450
uniprot id: A0A660HSZ2
names: Similarity
messages: Belongs to the citrate synthase family.

1715806:AOB57 RS09245
gene id: 1715806:AOB57_RS09245
uniprot id: A0A660HSR9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1715806:AOB57 RS10535
gene id: 1715806:AOB57_RS10535
uniprot id: A0A660HUN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1715806:AOB57 RS08715
gene id: 1715806:AOB57_RS08715
uniprot id: A0A660HSN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1715806:AOB57 RS05335
gene id: 1715806:AOB57_RS05335
uniprot id: A0A660HQY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

1715806:AOB57 RS13370
gene id: 1715806:AOB57_RS13370
uniprot id: A0A660HVB0
names: Similarity
messages: Belongs to the class-I fumarase family.

1715806:AOB57 RS02585
gene id: 1715806:AOB57_RS02585
uniprot id: A0A660HPN8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1715806:AOB57 RS09280
gene id: 1715806:AOB57_RS09280
uniprot id: A0A660HVS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1715806:AOB57 RS13180
gene id: 1715806:AOB57_RS13180
uniprot id: A0A660HUH6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1715806:AOB57 RS03615
gene id: 1715806:AOB57_RS03615
uniprot id: A0A660HQ77
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1715806:AOB57 RS08795
gene id: 1715806:AOB57_RS08795
uniprot id: A0A660HSM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1715806:AOB57 RS00205
gene id: 1715806:AOB57_RS00205
uniprot id: A0A660HNP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1715806:AOB57 RS03340
gene id: 1715806:AOB57_RS03340
uniprot id: A0A660HQK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

1715806:AOB57 RS14165
gene id: 1715806:AOB57_RS14165
uniprot id: A0A660HUZ4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Membrane

1715806:AOB57 RS08750
gene id: 1715806:AOB57_RS08750
uniprot id: A0A660HSK3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

1715806:AOB57 RS03545
gene id: 1715806:AOB57_RS03545
uniprot id: A0A7K4AW46
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Heterotetramer of 2 HacA and 2 HacB proteins.
messages: Hydro-lyase with broad substrate specificity for cis-unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4-tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4-tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS03765
gene id: 1715806:AOB57_RS03765
uniprot id: A0A660HQ94
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

1715806:AOB57 RS08225
gene id: 1715806:AOB57_RS08225
uniprot id: A0A660HSG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

1715806:AOB57 RS09365
gene id: 1715806:AOB57_RS09365
uniprot id: A0A660HST7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrF family.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

1715806:AOB57 RS00100
gene id: 1715806:AOB57_RS00100
uniprot id: A0A660HNI2
names: Similarity
messages: Belongs to the acylphosphatase family.

1715806:AOB57 RS03015
gene id: 1715806:AOB57_RS03015
uniprot id: A0A660HPT5
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS09390
gene id: 1715806:AOB57_RS09390
uniprot id: A0A660HU44
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

1715806:AOB57 RS03135
gene id: 1715806:AOB57_RS03135
uniprot id: A0A660HPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1715806:AOB57 RS02625
gene id: 1715806:AOB57_RS02625
uniprot id: A0A660HPM8
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1715806:AOB57 RS13210
gene id: 1715806:AOB57_RS13210
uniprot id: A0A660HUR3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1715806:AOB57 RS02765
gene id: 1715806:AOB57_RS02765
uniprot id: A0A660HPP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HdrA family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

1715806:AOB57 RS07390
gene id: 1715806:AOB57_RS07390
uniprot id: A0A660HW73
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1715806:AOB57 RS00080
gene id: 1715806:AOB57_RS00080
uniprot id: A0A7K4ATB2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS12545
gene id: 1715806:AOB57_RS12545
uniprot id: A0A660HUF1
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1715806:AOB57 RS13135
gene id: 1715806:AOB57_RS13135
uniprot id: A0A660HUU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1715806:AOB57 RS01945
gene id: 1715806:AOB57_RS01945
uniprot id: A0A660HPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1715806:AOB57 RS04000
gene id: 1715806:AOB57_RS04000
uniprot id: A0A660HQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS09605
gene id: 1715806:AOB57_RS09605
uniprot id: A0A660HSX3
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

1715806:AOB57 RS10595
gene id: 1715806:AOB57_RS10595
uniprot id: A0A660HTD8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1715806:AOB57 RS10755
gene id: 1715806:AOB57_RS10755
uniprot id: A0A660HUS4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1715806:AOB57 RS12475
gene id: 1715806:AOB57_RS12475
uniprot id: A0A660HUE2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1715806:AOB57 RS06815
gene id: 1715806:AOB57_RS06815
uniprot id: A0A660HRT3
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS08990
gene id: 1715806:AOB57_RS08990
uniprot id: A0A660HT39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1715806:AOB57 RS07175
gene id: 1715806:AOB57_RS07175
uniprot id: A0A660HSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS02950
gene id: 1715806:AOB57_RS02950
uniprot id: A0A660HPV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1715806:AOB57 RS05475
gene id: 1715806:AOB57_RS05475
uniprot id: A0A660HR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

1715806:AOB57 RS03920
gene id: 1715806:AOB57_RS03920
uniprot id: A0A660HQC5
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS12460
gene id: 1715806:AOB57_RS12460
uniprot id: A0A660HUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

1715806:AOB57 RS01680
gene id: 1715806:AOB57_RS01680
uniprot id: A0A660HPE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1715806:AOB57 RS04700
gene id: 1715806:AOB57_RS04700
uniprot id: A0A660HX86
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

1715806:AOB57 RS07720
gene id: 1715806:AOB57_RS07720
uniprot id: A0A660HS98
names: Similarity
messages: Belongs to the thymidylate kinase family.

1715806:AOB57 RS11030
gene id: 1715806:AOB57_RS11030
uniprot id: A0A660HUX4
names: Similarity
messages: Belongs to the UPF0228 family.

1715806:AOB57 RS05165
gene id: 1715806:AOB57_RS05165
uniprot id: A0A660HQV7
names: Function
names: Similarity
messages: Belongs to the dCTP deaminase family. Archaeal dUTPase subfamily.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1715806:AOB57 RS10410
gene id: 1715806:AOB57_RS10410
uniprot id: A0A660HVU8
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

1715806:AOB57 RS11055
gene id: 1715806:AOB57_RS11055
uniprot id: A0A660HU68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1715806:AOB57 RS13710
gene id: 1715806:AOB57_RS13710
uniprot id: A0A660HV01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1715806:AOB57 RS09495
gene id: 1715806:AOB57_RS09495
uniprot id: A0A7K4AYJ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS13535
gene id: 1715806:AOB57_RS13535
uniprot id: A0A660HUX6
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS00750
gene id: 1715806:AOB57_RS00750
uniprot id: A0A660HNY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1715806:AOB57 RS05985
gene id: 1715806:AOB57_RS05985
uniprot id: A0A660HR95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1715806:AOB57 RS11040
gene id: 1715806:AOB57_RS11040
uniprot id: A0A660HU61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1715806:AOB57 RS06980
gene id: 1715806:AOB57_RS06980
uniprot id: A0A660HRS2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
messages: Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.

1715806:AOB57 RS06575
gene id: 1715806:AOB57_RS06575
uniprot id: A0A660HRR0
names: Similarity
messages: Belongs to the PurH family.

1715806:AOB57 RS05775
gene id: 1715806:AOB57_RS05775
uniprot id: A0A660HRA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1715806:AOB57 RS03425
gene id: 1715806:AOB57_RS03425
uniprot id: A0A660HQ67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS13720
gene id: 1715806:AOB57_RS13720
uniprot id: A0A660HVJ3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

1715806:AOB57 RS00895
gene id: 1715806:AOB57_RS00895
uniprot id: A0A660HNW3
names: Similarity
messages: Belongs to the Nudix hydrolase family. NudC subfamily.

1715806:AOB57 RS00735
gene id: 1715806:AOB57_RS00735
uniprot id: A0A660HP87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

1715806:AOB57 RS05860
gene id: 1715806:AOB57_RS05860
uniprot id: A0A660HR86
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS07135
gene id: 1715806:AOB57_RS07135
uniprot id: A0A660HRZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS03320
gene id: 1715806:AOB57_RS03320
uniprot id: A0A660HQ50
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

1715806:AOB57 RS11360
gene id: 1715806:AOB57_RS11360
uniprot id: A0A660HTR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1715806:AOB57 RS05955
gene id: 1715806:AOB57_RS05955
uniprot id: A0A660HRC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.

1715806:AOB57 RS08120
gene id: 1715806:AOB57_RS08120
uniprot id: A0A660HSB5
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS01350
gene id: 1715806:AOB57_RS01350
uniprot id: A0A660HP91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofH family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

1715806:AOB57 RS00995
gene id: 1715806:AOB57_RS00995
uniprot id: A0A660HNY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1715806:AOB57 RS01415
gene id: 1715806:AOB57_RS01415
uniprot id: A0A660HP57
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS00290
gene id: 1715806:AOB57_RS00290
uniprot id: A0A660HP84
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS03260
gene id: 1715806:AOB57_RS03260
uniprot id: A0A660HQ39
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1715806:AOB57 RS12495
gene id: 1715806:AOB57_RS12495
uniprot id: A0A660HU91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1715806:AOB57 RS06445
gene id: 1715806:AOB57_RS06445
uniprot id: A0A660HS45
names: Similarity
messages: Belongs to the SUI1 family.

1715806:AOB57 RS10510
gene id: 1715806:AOB57_RS10510
uniprot id: A0A660HTA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1715806:AOB57 RS10010
gene id: 1715806:AOB57_RS10010
uniprot id: A0A660HTP1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1715806:AOB57 RS06265
gene id: 1715806:AOB57_RS06265
uniprot id: A0A660HRE9
names: Similarity
messages: Belongs to the UPF0292 family.

1715806:AOB57 RS07870
gene id: 1715806:AOB57_RS07870
uniprot id: A0A660HS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1715806:AOB57 RS13625
gene id: 1715806:AOB57_RS13625
uniprot id: A0A660HUT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1715806:AOB57 RS10515
gene id: 1715806:AOB57_RS10515
uniprot id: A0A660HT97
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1715806:AOB57 RS02400
gene id: 1715806:AOB57_RS02400
uniprot id: A0A660HPK6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1715806:AOB57 RS13840
gene id: 1715806:AOB57_RS13840
uniprot id: A0A660HVL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

1715806:AOB57 RS10470
gene id: 1715806:AOB57_RS10470
uniprot id: A0A660HTH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1715806:AOB57 RS09755
gene id: 1715806:AOB57_RS09755
uniprot id: A0A660HUA1
names: Similarity
messages: Belongs to the archaeal-type GPI family.

1715806:AOB57 RS10520
gene id: 1715806:AOB57_RS10520
uniprot id: A0A660HTI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1715806:AOB57 RS11000
gene id: 1715806:AOB57_RS11000
uniprot id: A0A660HU58
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

1715806:AOB57 RS00745
gene id: 1715806:AOB57_RS00745
uniprot id: A0A660HNS4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1715806:AOB57 RS05965
gene id: 1715806:AOB57_RS05965
uniprot id: A0A660HRV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS00295
gene id: 1715806:AOB57_RS00295
uniprot id: A0A660HNK2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1715806:AOB57 RS06855
gene id: 1715806:AOB57_RS06855
uniprot id: A0A660HVI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

1715806:AOB57 RS00695
gene id: 1715806:AOB57_RS00695
uniprot id: A0A660HNR6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS12615
gene id: 1715806:AOB57_RS12615
uniprot id: A0A660HV05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1715806:AOB57 RS06930
gene id: 1715806:AOB57_RS06930
uniprot id: A0A660HRR2
names: Similarity
messages: Belongs to the UPF0251 family.

1715806:AOB57 RS10225
gene id: 1715806:AOB57_RS10225
uniprot id: A0A660HTR5
names: Similarity
messages: Belongs to the IMPACT family.

1715806:AOB57 RS05305
gene id: 1715806:AOB57_RS05305
uniprot id: A0A660HR03
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1715806:AOB57 RS10610
gene id: 1715806:AOB57_RS10610
uniprot id: A0A660HTC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1715806:AOB57 RS12210
gene id: 1715806:AOB57_RS12210
uniprot id: A0A660HVH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

1715806:AOB57 RS07535
gene id: 1715806:AOB57_RS07535
uniprot id: A0A660HS67
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1715806:AOB57 RS03530
gene id: 1715806:AOB57_RS03530
uniprot id: A0A660HQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1715806:AOB57 RS01700
gene id: 1715806:AOB57_RS01700
uniprot id: A0A660HV83
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS13150
gene id: 1715806:AOB57_RS13150
uniprot id: A0A660HVY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1715806:AOB57 RS12015
gene id: 1715806:AOB57_RS12015
uniprot id: A0A660HU07
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

1715806:AOB57 RS07300
gene id: 1715806:AOB57_RS07300
uniprot id: A0A660HS44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1715806:AOB57 RS01935
gene id: 1715806:AOB57_RS01935
uniprot id: A0A660HPA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS04720
gene id: 1715806:AOB57_RS04720
uniprot id: A0A660HR45
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

1715806:AOB57 RS11395
gene id: 1715806:AOB57_RS11395
uniprot id: A0A660HTX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1715806:AOB57 RS11380
gene id: 1715806:AOB57_RS11380
uniprot id: A0A660HVN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1715806:AOB57 RS01395
gene id: 1715806:AOB57_RS01395
uniprot id: A0A660HP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: FPO is composed of at least 12 different subunits. Subunits FpoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: FPO shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to quinones in the F(420)H(2):heterodisulfide oxidoreduction chain. The immediate electron acceptor for the enzyme in this species is believed to be methanophenazine. Couples the redox reaction to proton translocation (for every two electrons transferred, 0.9 hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: Membrane

1715806:AOB57 RS12635
gene id: 1715806:AOB57_RS12635
uniprot id: A0A660HUJ2
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

1715806:AOB57 RS10890
gene id: 1715806:AOB57_RS10890
uniprot id: A0A660HTH0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS03325
gene id: 1715806:AOB57_RS03325
uniprot id: A0A660HQ29
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1715806:AOB57 RS05500
gene id: 1715806:AOB57_RS05500
uniprot id: A0A660HVF2
names: Similarity
messages: Belongs to the Ahb/Nir family.

1715806:AOB57 RS07040
gene id: 1715806:AOB57_RS07040
uniprot id: A0A660HSD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1715806:AOB57 RS12180
gene id: 1715806:AOB57_RS12180
uniprot id: A0A660HU36
names: Similarity
messages: Belongs to the UPF0212 family.

1715806:AOB57 RS02620
gene id: 1715806:AOB57_RS02620
uniprot id: A0A660HQ88
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1715806:AOB57 RS04905
gene id: 1715806:AOB57_RS04905
uniprot id: A0A7K4AUS0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS02245
gene id: 1715806:AOB57_RS02245
uniprot id: A0A660HPG3
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS05745
gene id: 1715806:AOB57_RS05745
uniprot id: A0A660HR80
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS14315
gene id: 1715806:AOB57_RS14315
uniprot id: A0A660HV97
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1715806:AOB57 RS06590
gene id: 1715806:AOB57_RS06590
uniprot id: A0A660HRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS07075
gene id: 1715806:AOB57_RS07075
uniprot id: A0A660HS01
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1715806:AOB57 RS02880
gene id: 1715806:AOB57_RS02880
uniprot id: A0A7K4ASL9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS05000
gene id: 1715806:AOB57_RS05000
uniprot id: A0A660HVV0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1715806:AOB57 RS11970
gene id: 1715806:AOB57_RS11970
uniprot id: A0A660HTX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS10805
gene id: 1715806:AOB57_RS10805
uniprot id: A0A660HTK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

1715806:AOB57 RS06510
gene id: 1715806:AOB57_RS06510
uniprot id: A0A660HRL6
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

1715806:AOB57 RS10650
gene id: 1715806:AOB57_RS10650
uniprot id: A0A660HTE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1715806:AOB57 RS05810
gene id: 1715806:AOB57_RS05810
uniprot id: A0A660HRM1
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

1715806:AOB57 RS11400
gene id: 1715806:AOB57_RS11400
uniprot id: A0A660HTV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1715806:AOB57 RS10540
gene id: 1715806:AOB57_RS10540
uniprot id: A0A660HTY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS10660
gene id: 1715806:AOB57_RS10660
uniprot id: A0A660HU02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS11365
gene id: 1715806:AOB57_RS11365
uniprot id: A0A660HTR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1715806:AOB57 RS08075
gene id: 1715806:AOB57_RS08075
uniprot id: A0A660HSE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS00075
gene id: 1715806:AOB57_RS00075
uniprot id: A0A660HNF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

1715806:AOB57 RS05825
gene id: 1715806:AOB57_RS05825
uniprot id: A0A660HR49
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

1715806:AOB57 RS07030
gene id: 1715806:AOB57_RS07030
uniprot id: A0A660HRX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1715806:AOB57 RS05465
gene id: 1715806:AOB57_RS05465
uniprot id: A0A660HR65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS10150
gene id: 1715806:AOB57_RS10150
uniprot id: A0A660HTQ9
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1715806:AOB57 RS04475
gene id: 1715806:AOB57_RS04475
uniprot id: A0A660HQI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1715806:AOB57 RS09375
gene id: 1715806:AOB57_RS09375
uniprot id: A0A660HT18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MtrH family.
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

1715806:AOB57 RS02830
gene id: 1715806:AOB57_RS02830
uniprot id: A0A660HPT2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1715806:AOB57 RS11370
gene id: 1715806:AOB57_RS11370
uniprot id: A0A660HUB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS03870
gene id: 1715806:AOB57_RS03870
uniprot id: A0A660HQ89
names: Similarity
messages: Belongs to the pyruvate kinase family.

1715806:AOB57 RS11440
gene id: 1715806:AOB57_RS11440
uniprot id: A0A660HTP8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: SAH is a product of SAM methyltransferases and is known to be a feedback inhibitor of these enzymes. As a result of this inhibition, organisms have evolved efficient enzymes to metabolize SAH via different pathways. The pathway found in methanogens differs from the canonical pathway, it uses the deamination of S-adenosyl-L-homocysteine to form S-inosyl-L-homocysteine for the regeneration of SAM from S-adenosyl-L-homocysteine.

1715806:AOB57 RS03775
gene id: 1715806:AOB57_RS03775
uniprot id: A0A660HQ93
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1715806:AOB57 RS05315
gene id: 1715806:AOB57_RS05315
uniprot id: A0A660HRJ1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1715806:AOB57 RS08690
gene id: 1715806:AOB57_RS08690
uniprot id: A0A660HSJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS02700
gene id: 1715806:AOB57_RS02700
uniprot id: A0A660HPP0
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1715806:AOB57 RS08755
gene id: 1715806:AOB57_RS08755
uniprot id: A0A660HSJ3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1715806:AOB57 RS00170
gene id: 1715806:AOB57_RS00170
uniprot id: A0A660HNI4
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS02995
gene id: 1715806:AOB57_RS02995
uniprot id: A0A660HPX7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS09930
gene id: 1715806:AOB57_RS09930
uniprot id: A0A660HVN2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1715806:AOB57 RS06570
gene id: 1715806:AOB57_RS06570
uniprot id: A0A660HRK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

1715806:AOB57 RS08840
gene id: 1715806:AOB57_RS08840
uniprot id: A0A660HT65
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1715806:AOB57 RS09915
gene id: 1715806:AOB57_RS09915
uniprot id: A0A660HT94
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS07150
gene id: 1715806:AOB57_RS07150
uniprot id: A0A660HVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1715806:AOB57 RS00820
gene id: 1715806:AOB57_RS00820
uniprot id: A0A660HNT9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1715806:AOB57 RS13230
gene id: 1715806:AOB57_RS13230
uniprot id: A0A660HUM2
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS03620
gene id: 1715806:AOB57_RS03620
uniprot id: A0A660HW04
names: Subcellular Location Annotation
messages: Cytoplasm

1715806:AOB57 RS04090
gene id: 1715806:AOB57_RS04090
uniprot id: A0A660HQB2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1715806:AOB57 RS12005
gene id: 1715806:AOB57_RS12005
uniprot id: A0A660HU21
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

1715806:AOB57 RS09185
gene id: 1715806:AOB57_RS09185
uniprot id: A0A660HSQ4
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.

1715806:AOB57 RS03605
gene id: 1715806:AOB57_RS03605
uniprot id: A0A660HQ32
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1715806:AOB57 RS11550
gene id: 1715806:AOB57_RS11550
uniprot id: A0A660HTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1715806:AOB57 RS05605
gene id: 1715806:AOB57_RS05605
uniprot id: A0A660HR22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS03080
gene id: 1715806:AOB57_RS03080
uniprot id: A0A660HPU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1715806:AOB57 RS09215
gene id: 1715806:AOB57_RS09215
uniprot id: A0A660HSU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1715806:AOB57 RS02055
gene id: 1715806:AOB57_RS02055
uniprot id: A0A660HPC9
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS08665
gene id: 1715806:AOB57_RS08665
uniprot id: A0A660HTS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1715806:AOB57 RS10065
gene id: 1715806:AOB57_RS10065
uniprot id: A0A660HVU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS14285
gene id: 1715806:AOB57_RS14285
uniprot id: A0A660HV90
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS07115
gene id: 1715806:AOB57_RS07115
uniprot id: A0A660HS93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1715806:AOB57 RS04730
gene id: 1715806:AOB57_RS04730
uniprot id: A0A660HQP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1715806:AOB57 RS11375
gene id: 1715806:AOB57_RS11375
uniprot id: A0A660HTP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1715806:AOB57 RS13580
gene id: 1715806:AOB57_RS13580
uniprot id: A0A660HUP6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1715806:AOB57 RS01715
gene id: 1715806:AOB57_RS01715
uniprot id: A0A660HP90
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS05470
gene id: 1715806:AOB57_RS05470
uniprot id: A0A660HR46
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1715806:AOB57 RS07250
gene id: 1715806:AOB57_RS07250
uniprot id: A0A660HS35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1715806:AOB57 RS13635
gene id: 1715806:AOB57_RS13635
uniprot id: A0A660HUZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1715806:AOB57 RS06300
gene id: 1715806:AOB57_RS06300
uniprot id: A0A660HRH1
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS10575
gene id: 1715806:AOB57_RS10575
uniprot id: A0A660HTI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1715806:AOB57 RS01220
gene id: 1715806:AOB57_RS01220
uniprot id: A0A660HP08
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS01855
gene id: 1715806:AOB57_RS01855
uniprot id: A0A660HPB3
names: Similarity
messages: Belongs to the peptidase U62 family.

1715806:AOB57 RS12230
gene id: 1715806:AOB57_RS12230
uniprot id: A0A660HW33
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1715806:AOB57 RS05330
gene id: 1715806:AOB57_RS05330
uniprot id: A0A660HRE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS08640
gene id: 1715806:AOB57_RS08640
uniprot id: A0A660HSI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
messages: Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
messages: Homotetramer. Interacts with SepCysS.

1715806:AOB57 RS11875
gene id: 1715806:AOB57_RS11875
uniprot id: A0A660HVB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1715806:AOB57 RS08870
gene id: 1715806:AOB57_RS08870
uniprot id: A0A660HSK8
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

1715806:AOB57 RS08745
gene id: 1715806:AOB57_RS08745
uniprot id: A0A660HT03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

1715806:AOB57 RS10745
gene id: 1715806:AOB57_RS10745
uniprot id: A0A660HTL8
names: Similarity
messages: Belongs to the HupF/HypC family.

1715806:AOB57 RS05670
gene id: 1715806:AOB57_RS05670
uniprot id: A0A660HVP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS05340
gene id: 1715806:AOB57_RS05340
uniprot id: A0A660HQX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS10580
gene id: 1715806:AOB57_RS10580
uniprot id: A0A660HTF7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1715806:AOB57 RS00840
gene id: 1715806:AOB57_RS00840
uniprot id: A0A660HNV4
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS08520
gene id: 1715806:AOB57_RS08520
uniprot id: A0A660HSH0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS07600
gene id: 1715806:AOB57_RS07600
uniprot id: A0A660HS32
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS04085
gene id: 1715806:AOB57_RS04085
uniprot id: A0A660HQE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS08070
gene id: 1715806:AOB57_RS08070
uniprot id: A0A660HSE5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS00060
gene id: 1715806:AOB57_RS00060
uniprot id: A0A660HNE8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1715806:AOB57 RS03310
gene id: 1715806:AOB57_RS03310
uniprot id: A0A660HQ10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

1715806:AOB57 RS01025
gene id: 1715806:AOB57_RS01025
uniprot id: A0A660HNY4
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

1715806:AOB57 RS06555
gene id: 1715806:AOB57_RS06555
uniprot id: A0A660HRM8
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS13145
gene id: 1715806:AOB57_RS13145
uniprot id: A0A660HUS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS09320
gene id: 1715806:AOB57_RS09320
uniprot id: A0A660HT04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

1715806:AOB57 RS12200
gene id: 1715806:AOB57_RS12200
uniprot id: A0A660HUB2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1715806:AOB57 RS10935
gene id: 1715806:AOB57_RS10935
uniprot id: A0A660HTK0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS14000
gene id: 1715806:AOB57_RS14000
uniprot id: A0A660HWK6
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

1715806:AOB57 RS05370
gene id: 1715806:AOB57_RS05370
uniprot id: A0A660HRK4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1715806:AOB57 RS07010
gene id: 1715806:AOB57_RS07010
uniprot id: A0A660HVH3
names: Similarity
messages: Belongs to the UPF0215 family.

1715806:AOB57 RS09325
gene id: 1715806:AOB57_RS09325
uniprot id: A0A660HWG2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

1715806:AOB57 RS10530
gene id: 1715806:AOB57_RS10530
uniprot id: A0A660HTE8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1715806:AOB57 RS08065
gene id: 1715806:AOB57_RS08065
uniprot id: A0A660HSH8
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

1715806:AOB57 RS06255
gene id: 1715806:AOB57_RS06255
uniprot id: A0A660HRF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1715806:AOB57 RS06165
gene id: 1715806:AOB57_RS06165
uniprot id: A0A660HRA7
names: Similarity
messages: Belongs to the TrpF family.

1715806:AOB57 RS09550
gene id: 1715806:AOB57_RS09550
uniprot id: A0A660HVK2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1715806:AOB57 RS08995
gene id: 1715806:AOB57_RS08995
uniprot id: A0A660HSN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS03250
gene id: 1715806:AOB57_RS03250
uniprot id: A0A660HQ01
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS08355
gene id: 1715806:AOB57_RS08355
uniprot id: A0A660HSK9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1715806:AOB57 RS08740
gene id: 1715806:AOB57_RS08740
uniprot id: A0A660HSM1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1715806:AOB57 RS14140
gene id: 1715806:AOB57_RS14140
uniprot id: A0A660HV70
names: Similarity
messages: Belongs to the glutamine synthetase family.

1715806:AOB57 RS06655
gene id: 1715806:AOB57_RS06655
uniprot id: A0A660HRP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS13725
gene id: 1715806:AOB57_RS13725
uniprot id: A0A660HVV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

1715806:AOB57 RS12165
gene id: 1715806:AOB57_RS12165
uniprot id: A0A660HU86
names: Similarity
messages: Belongs to the glutaredoxin family.

1715806:AOB57 RS03070
gene id: 1715806:AOB57_RS03070
uniprot id: A0A660HPV7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS05320
gene id: 1715806:AOB57_RS05320
uniprot id: A0A660HR11
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1715806:AOB57 RS01465
gene id: 1715806:AOB57_RS01465
uniprot id: A0A660HVV0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1715806:AOB57 RS11390
gene id: 1715806:AOB57_RS11390
uniprot id: A0A660HTZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

1715806:AOB57 RS07760
gene id: 1715806:AOB57_RS07760
uniprot id: A0A660HSA2
names: Subcellular Location Annotation
messages: Cell membrane

1715806:AOB57 RS12855
gene id: 1715806:AOB57_RS12855
uniprot id: A0A660HV45
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS00555
gene id: 1715806:AOB57_RS00555
uniprot id: A0A660HP54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1715806:AOB57 RS11560
gene id: 1715806:AOB57_RS11560
uniprot id: A0A660HTR7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

1715806:AOB57 RS08305
gene id: 1715806:AOB57_RS08305
uniprot id: A0A660HTL4
names: Similarity
messages: Belongs to the UPF0200 family.

1715806:AOB57 RS05535
gene id: 1715806:AOB57_RS05535
uniprot id: A0A660HR58
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS02835
gene id: 1715806:AOB57_RS02835
uniprot id: A0A660HVJ5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1715806:AOB57 RS13770
gene id: 1715806:AOB57_RS13770
uniprot id: A0A660HVJ9
names: Similarity
messages: Belongs to the PspA/IM30 family.

1715806:AOB57 RS00365
gene id: 1715806:AOB57_RS00365
uniprot id: A0A660HNL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HdrA family.
messages: Cytoplasm
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

1715806:AOB57 RS01425
gene id: 1715806:AOB57_RS01425
uniprot id: A0A660HP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1715806:AOB57 RS11075
gene id: 1715806:AOB57_RS11075
uniprot id: A0A660HTU1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

1715806:AOB57 RS12020
gene id: 1715806:AOB57_RS12020
uniprot id: A0A660HTY6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1715806:AOB57 RS07285
gene id: 1715806:AOB57_RS07285
uniprot id: A0A660HSC1
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase gamma subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

1715806:AOB57 RS10725
gene id: 1715806:AOB57_RS10725
uniprot id: A0A660HU11
names: Similarity
messages: Belongs to the HypE family.

1715806:AOB57 RS09345
gene id: 1715806:AOB57_RS09345
uniprot id: A0A660HTE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrD family.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

1715806:AOB57 RS05695
gene id: 1715806:AOB57_RS05695
uniprot id: A0A660HR53
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1715806:AOB57 RS10240
gene id: 1715806:AOB57_RS10240
uniprot id: A0A660HT51
names: Subcellular Location Annotation
messages: Cell membrane

1715806:AOB57 RS08680
gene id: 1715806:AOB57_RS08680
uniprot id: A0A660HSL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1715806:AOB57 RS06710
gene id: 1715806:AOB57_RS06710
uniprot id: A0A660HRQ3
names: Similarity
messages: Belongs to the AOR/FOR family.

1715806:AOB57 RS01235
gene id: 1715806:AOB57_RS01235
uniprot id: A0A660HP71
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1715806:AOB57 RS01305
gene id: 1715806:AOB57_RS01305
uniprot id: A0A660HP81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1715806:AOB57 RS09505
gene id: 1715806:AOB57_RS09505
uniprot id: A0A660HSZ8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1715806:AOB57 RS08320
gene id: 1715806:AOB57_RS08320
uniprot id: A0A660HSG5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS13080
gene id: 1715806:AOB57_RS13080
uniprot id: A0A660HWR6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1715806:AOB57 RS05255
gene id: 1715806:AOB57_RS05255
uniprot id: A0A7K4AS15
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS14115
gene id: 1715806:AOB57_RS14115
uniprot id: A0A660HV68
names: Similarity
messages: Belongs to the UPF0237 family.

1715806:AOB57 RS10495
gene id: 1715806:AOB57_RS10495
uniprot id: A0A660HTC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

1715806:AOB57 RS08590
gene id: 1715806:AOB57_RS08590
uniprot id: A0A660HSL5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

1715806:AOB57 RS13545
gene id: 1715806:AOB57_RS13545
uniprot id: A0A660HUZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS06270
gene id: 1715806:AOB57_RS06270
uniprot id: A0A660HRC6
names: Similarity
messages: Belongs to the UPF0235 family.

1715806:AOB57 RS13665
gene id: 1715806:AOB57_RS13665
uniprot id: A0A660HVI0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1715806:AOB57 RS04390
gene id: 1715806:AOB57_RS04390
uniprot id: A0A660HQJ8
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1715806:AOB57 RS03740
gene id: 1715806:AOB57_RS03740
uniprot id: A0A660HQ96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CdhD family.
messages: Heterodimer of delta and gamma chains. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex.

1715806:AOB57 RS12310
gene id: 1715806:AOB57_RS12310
uniprot id: A0A660HUE8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1715806:AOB57 RS08915
gene id: 1715806:AOB57_RS08915
uniprot id: A0A660HVV0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1715806:AOB57 RS11980
gene id: 1715806:AOB57_RS11980
uniprot id: A0A660HU74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS00065
gene id: 1715806:AOB57_RS00065
uniprot id: A0A660HNF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS09745
gene id: 1715806:AOB57_RS09745
uniprot id: A0A660HT66
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1715806:AOB57 RS04715
gene id: 1715806:AOB57_RS04715
uniprot id: A0A660HQP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

1715806:AOB57 RS09385
gene id: 1715806:AOB57_RS09385
uniprot id: A0A660HSY3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1715806:AOB57 RS05830
gene id: 1715806:AOB57_RS05830
uniprot id: A0A660HRC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1715806:AOB57 RS03725
gene id: 1715806:AOB57_RS03725
uniprot id: A0A660HQ79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CdhB family.
messages: Heterotetramer of two alpha and two epsilon subunits. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta subunits with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation.

1715806:AOB57 RS07160
gene id: 1715806:AOB57_RS07160
uniprot id: A0A660HSF3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1715806:AOB57 RS05375
gene id: 1715806:AOB57_RS05375
uniprot id: A0A660HR21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1715806:AOB57 RS06175
gene id: 1715806:AOB57_RS06175
uniprot id: A0A660HRG9
names: Similarity
messages: Belongs to the PDCD5 family.

1715806:AOB57 RS07525
gene id: 1715806:AOB57_RS07525
uniprot id: A0A660HS04
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1715806:AOB57 RS03895
gene id: 1715806:AOB57_RS03895
uniprot id: A0A660HVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1715806:AOB57 RS08215
gene id: 1715806:AOB57_RS08215
uniprot id: A0A660HSB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

1715806:AOB57 RS11755
gene id: 1715806:AOB57_RS11755
uniprot id: A0A660HVX5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1715806:AOB57 RS10820
gene id: 1715806:AOB57_RS10820
uniprot id: A0A660HTH3
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS01580
gene id: 1715806:AOB57_RS01580
uniprot id: A0A660HP58
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1715806:AOB57 RS10455
gene id: 1715806:AOB57_RS10455
uniprot id: A0A660HTV8
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

1715806:AOB57 RS03105
gene id: 1715806:AOB57_RS03105
uniprot id: A0A660HPU8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

1715806:AOB57 RS09480
gene id: 1715806:AOB57_RS09480
uniprot id: A0A660HSV6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1715806:AOB57 RS08730
gene id: 1715806:AOB57_RS08730
uniprot id: A0A660HT49
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS01860
gene id: 1715806:AOB57_RS01860
uniprot id: A0A660HP98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1715806:AOB57 RS12500
gene id: 1715806:AOB57_RS12500
uniprot id: A0A660HU70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1715806:AOB57 RS01530
gene id: 1715806:AOB57_RS01530
uniprot id: A0A660HP62
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1715806:AOB57 RS11565
gene id: 1715806:AOB57_RS11565
uniprot id: A0A660HU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1715806:AOB57 RS12610
gene id: 1715806:AOB57_RS12610
uniprot id: A0A660HVT5
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

1715806:AOB57 RS06630
gene id: 1715806:AOB57_RS06630
uniprot id: A0A660HRS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

1715806:AOB57 RS02605
gene id: 1715806:AOB57_RS02605
uniprot id: A0A660HPP8
names: Function
messages: Part of a potassium transport system.

1715806:AOB57 RS14130
gene id: 1715806:AOB57_RS14130
uniprot id: A0A660HVN8
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS07880
gene id: 1715806:AOB57_RS07880
uniprot id: A0A660HSB6
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

1715806:AOB57 RS01140
gene id: 1715806:AOB57_RS01140
uniprot id: A0A660HNZ1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

1715806:AOB57 RS10845
gene id: 1715806:AOB57_RS10845
uniprot id: A0A660HTF1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1715806:AOB57 RS08220
gene id: 1715806:AOB57_RS08220
uniprot id: A0A660HSJ1
names: Subcellular Location Annotation
messages: Cytoplasm

1715806:AOB57 RS09730
gene id: 1715806:AOB57_RS09730
uniprot id: A0A660HSZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS00725
gene id: 1715806:AOB57_RS00725
uniprot id: A0A660HNS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1715806:AOB57 RS01590
gene id: 1715806:AOB57_RS01590
uniprot id: A0A660HP70
names: Similarity
messages: Belongs to the UPF0758 family.

1715806:AOB57 RS09980
gene id: 1715806:AOB57_RS09980
uniprot id: A0A660HTA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1715806:AOB57 RS11410
gene id: 1715806:AOB57_RS11410
uniprot id: A0A660HUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1715806:AOB57 RS05690
gene id: 1715806:AOB57_RS05690
uniprot id: A0A660HVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1715806:AOB57 RS09360
gene id: 1715806:AOB57_RS09360
uniprot id: A0A660HTA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrA family.
messages: Binds 1 5-hydroxybenzimidazolylcobamide group.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

1715806:AOB57 RS12095
gene id: 1715806:AOB57_RS12095
uniprot id: A0A660HU93
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1715806:AOB57 RS08455
gene id: 1715806:AOB57_RS08455
uniprot id: A0A660HSV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

1715806:AOB57 RS04455
gene id: 1715806:AOB57_RS04455
uniprot id: A0A660HQK9
names: Similarity
messages: Belongs to the AAA ATPase family.

1715806:AOB57 RS12160
gene id: 1715806:AOB57_RS12160
uniprot id: A0A660HUQ6
names: Subcellular Location Annotation
messages: Cytoplasm

1715806:AOB57 RS05970
gene id: 1715806:AOB57_RS05970
uniprot id: A0A660HRB8
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1715806:AOB57 RS10655
gene id: 1715806:AOB57_RS10655
uniprot id: A0A660HTF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1715806:AOB57 RS02615
gene id: 1715806:AOB57_RS02615
uniprot id: A0A660HPN4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS07740
gene id: 1715806:AOB57_RS07740
uniprot id: A0A660HSL6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1715806:AOB57 RS00640
gene id: 1715806:AOB57_RS00640
uniprot id: A0A660HNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS08800
gene id: 1715806:AOB57_RS08800
uniprot id: A0A660HT12
names: Similarity
messages: Belongs to the aspartokinase family.

1715806:AOB57 RS09985
gene id: 1715806:AOB57_RS09985
uniprot id: A0A660HVT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS06615
gene id: 1715806:AOB57_RS06615
uniprot id: A0A660HS15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1715806:AOB57 RS10015
gene id: 1715806:AOB57_RS10015
uniprot id: A0A660HT46
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1715806:AOB57 RS13715
gene id: 1715806:AOB57_RS13715
uniprot id: A0A660HUW1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1715806:AOB57 RS13220
gene id: 1715806:AOB57_RS13220
uniprot id: A0A660HVR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS06780
gene id: 1715806:AOB57_RS06780
uniprot id: A0A660HRR3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS12850
gene id: 1715806:AOB57_RS12850
uniprot id: A0A660HUH8
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS00220
gene id: 1715806:AOB57_RS00220
uniprot id: A0A660HVA5
names: Similarity
messages: Belongs to the UPF0145 family.

1715806:AOB57 RS09870
gene id: 1715806:AOB57_RS09870
uniprot id: A0A660HT83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS13890
gene id: 1715806:AOB57_RS13890
uniprot id: A0A660HVK0
names: Subcellular Location Annotation
messages: Cell membrane

1715806:AOB57 RS08855
gene id: 1715806:AOB57_RS08855
uniprot id: A0A660HT20
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

1715806:AOB57 RS13750
gene id: 1715806:AOB57_RS13750
uniprot id: A0A660HWE1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

1715806:AOB57 RS12320
gene id: 1715806:AOB57_RS12320
uniprot id: A0A660HUC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1715806:AOB57 RS08385
gene id: 1715806:AOB57_RS08385
uniprot id: A0A660HSH6
names: Similarity
messages: Belongs to the DtxR/MntR family.

1715806:AOB57 RS12065
gene id: 1715806:AOB57_RS12065
uniprot id: A0A660HU62
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1715806:AOB57 RS11110
gene id: 1715806:AOB57_RS11110
uniprot id: A0A660HU78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1715806:AOB57 RS00830
gene id: 1715806:AOB57_RS00830
uniprot id: A0A660HP01
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1715806:AOB57 RS04365
gene id: 1715806:AOB57_RS04365
uniprot id: A0A660HQK6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1715806:AOB57 RS01585
gene id: 1715806:AOB57_RS01585
uniprot id: A0A7K4AVR8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS10125
gene id: 1715806:AOB57_RS10125
uniprot id: A0A660HTB4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1715806:AOB57 RS12630
gene id: 1715806:AOB57_RS12630
uniprot id: A0A660HUL0
names: Similarity
messages: Belongs to the ATPase gamma chain family.

1715806:AOB57 RS12170
gene id: 1715806:AOB57_RS12170
uniprot id: A0A660HU52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

1715806:AOB57 RS10960
gene id: 1715806:AOB57_RS10960
uniprot id: A0A660HTQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1715806:AOB57 RS07260
gene id: 1715806:AOB57_RS07260
uniprot id: A0A660HS19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1715806:AOB57 RS06005
gene id: 1715806:AOB57_RS06005
uniprot id: A0A660HRD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1715806:AOB57 RS05885
gene id: 1715806:AOB57_RS05885
uniprot id: A0A7K4AWJ8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS01335
gene id: 1715806:AOB57_RS01335
uniprot id: A0A660HPI0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

1715806:AOB57 RS12130
gene id: 1715806:AOB57_RS12130
uniprot id: A0A660HU25
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1715806:AOB57 RS02445
gene id: 1715806:AOB57_RS02445
uniprot id: A0A660HQ60
names: Similarity
messages: Belongs to the MtrH family.

1715806:AOB57 RS00285
gene id: 1715806:AOB57_RS00285
uniprot id: A0A660HNK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS01380
gene id: 1715806:AOB57_RS01380
uniprot id: A0A660HP25
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1715806:AOB57 RS07785
gene id: 1715806:AOB57_RS07785
uniprot id: A0A660HS95
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1715806:AOB57 RS00510
gene id: 1715806:AOB57_RS00510
uniprot id: A0A660HNP3
names: Similarity
messages: Belongs to the AOR/FOR family.

1715806:AOB57 RS01545
gene id: 1715806:AOB57_RS01545
uniprot id: A0A660HP46
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS08400
gene id: 1715806:AOB57_RS08400
uniprot id: A0A660HVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

1715806:AOB57 RS13995
gene id: 1715806:AOB57_RS13995
uniprot id: A0A660HV93
names: Similarity
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.

1715806:AOB57 RS00615
gene id: 1715806:AOB57_RS00615
uniprot id: A0A660HNQ0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1715806:AOB57 RS09330
gene id: 1715806:AOB57_RS09330
uniprot id: A0A660HSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1715806:AOB57 RS14060
gene id: 1715806:AOB57_RS14060
uniprot id: A0A660HVA3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1715806:AOB57 RS04685
gene id: 1715806:AOB57_RS04685
uniprot id: A0A660HQM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1715806:AOB57 RS05365
gene id: 1715806:AOB57_RS05365
uniprot id: A0A660HQX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1715806:AOB57 RS07025
gene id: 1715806:AOB57_RS07025
uniprot id: A0A660HRX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1715806:AOB57 RS03905
gene id: 1715806:AOB57_RS03905
uniprot id: A0A660HQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS13065
gene id: 1715806:AOB57_RS13065
uniprot id: A0A660HUI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

1715806:AOB57 RS04810
gene id: 1715806:AOB57_RS04810
uniprot id: A0A660HQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1715806:AOB57 RS00325
gene id: 1715806:AOB57_RS00325
uniprot id: A0A660HWV2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1715806:AOB57 RS02395
gene id: 1715806:AOB57_RS02395
uniprot id: A0A660HPI6
names: Similarity
messages: Belongs to the DMRL synthase family.

1715806:AOB57 RS04380
gene id: 1715806:AOB57_RS04380
uniprot id: A0A660HR38
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1715806:AOB57 RS09940
gene id: 1715806:AOB57_RS09940
uniprot id: A0A660HUD1
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

1715806:AOB57 RS01805
gene id: 1715806:AOB57_RS01805
uniprot id: A0A660HPB9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS06835
gene id: 1715806:AOB57_RS06835
uniprot id: A0A660HRS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS03155
gene id: 1715806:AOB57_RS03155
uniprot id: A0A660HPV8
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

1715806:AOB57 RS12000
gene id: 1715806:AOB57_RS12000
uniprot id: A0A660HU54
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1715806:AOB57 RS03175
gene id: 1715806:AOB57_RS03175
uniprot id: A0A7K4AUD3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS07220
gene id: 1715806:AOB57_RS07220
uniprot id: A0A660HSF7
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1715806:AOB57 RS08430
gene id: 1715806:AOB57_RS08430
uniprot id: A0A660HTN3
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1715806:AOB57 RS14050
gene id: 1715806:AOB57_RS14050
uniprot id: A0A660HV57
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS12420
gene id: 1715806:AOB57_RS12420
uniprot id: A0A660HUU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

1715806:AOB57 RS10855
gene id: 1715806:AOB57_RS10855
uniprot id: A0A660HTN8
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1715806:AOB57 RS00985
gene id: 1715806:AOB57_RS00985
uniprot id: A0A660HP31
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1715806:AOB57 RS12760
gene id: 1715806:AOB57_RS12760
uniprot id: A0A660HUL3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS06215
gene id: 1715806:AOB57_RS06215
uniprot id: A0A660HRB6
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS08095
gene id: 1715806:AOB57_RS08095
uniprot id: A0A660HSE2
names: Function
names: Similarity
messages: Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10-methylenetetrahydromethanopterin.
messages: Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate.
messages: In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
messages: In the N-terminal section; belongs to the formaldehyde-activating enzyme family.

1715806:AOB57 RS05160
gene id: 1715806:AOB57_RS05160
uniprot id: A0A660HRB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

1715806:AOB57 RS05035
gene id: 1715806:AOB57_RS05035
uniprot id: A0A660HQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1715806:AOB57 RS00720
gene id: 1715806:AOB57_RS00720
uniprot id: A0A660HPE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1715806:AOB57 RS02610
gene id: 1715806:AOB57_RS02610
uniprot id: A0A660HPR1
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1715806:AOB57 RS06550
gene id: 1715806:AOB57_RS06550
uniprot id: A0A660HS64
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS02435
gene id: 1715806:AOB57_RS02435
uniprot id: A0A660HPM9
names: Similarity
messages: Belongs to the MtxX family.

1715806:AOB57 RS00825
gene id: 1715806:AOB57_RS00825
uniprot id: A0A660HNT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1715806:AOB57 RS09250
gene id: 1715806:AOB57_RS09250
uniprot id: A0A660HWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1715806:AOB57 RS09370
gene id: 1715806:AOB57_RS09370
uniprot id: A0A660HST2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrG family.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

1715806:AOB57 RS09400
gene id: 1715806:AOB57_RS09400
uniprot id: A0A660HVM3
names: Subunit
messages: Homotetramer.

1715806:AOB57 RS07445
gene id: 1715806:AOB57_RS07445
uniprot id: A0A660HSJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1715806:AOB57 RS11785
gene id: 1715806:AOB57_RS11785
uniprot id: A0A660HUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1715806:AOB57 RS05540
gene id: 1715806:AOB57_RS05540
uniprot id: A0A660HR51
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS02075
gene id: 1715806:AOB57_RS02075
uniprot id: A0A660HQ02
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
messages: Binds 1 Zn(2+) ion per subunit. This ion is coordinated with 2 cysteines, 1 glutamate and a water molecule that dissociates from the zinc ion to allow the coordination of the amino group of the serine substrate, which is essential for catalysis.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is presumably involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS12640
gene id: 1715806:AOB57_RS12640
uniprot id: A0A660HUI8
names: Function
names: Subcellular Location Annotation
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1715806:AOB57 RS08055
gene id: 1715806:AOB57_RS08055
uniprot id: A0A660HSQ3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1715806:AOB57 RS06830
gene id: 1715806:AOB57_RS06830
uniprot id: A0A660HRS8
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS02945
gene id: 1715806:AOB57_RS02945
uniprot id: A0A660HPS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1715806:AOB57 RS01345
gene id: 1715806:AOB57_RS01345
uniprot id: A0A660HP19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

1715806:AOB57 RS10585
gene id: 1715806:AOB57_RS10585
uniprot id: A0A660HUP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1715806:AOB57 RS10605
gene id: 1715806:AOB57_RS10605
uniprot id: A0A660HTZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1715806:AOB57 RS13365
gene id: 1715806:AOB57_RS13365
uniprot id: A0A660HW36
names: Similarity
messages: Belongs to the class-I fumarase family.

1715806:AOB57 RS01515
gene id: 1715806:AOB57_RS01515
uniprot id: A0A660HP60
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS08310
gene id: 1715806:AOB57_RS08310
uniprot id: A0A660HSZ6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1715806:AOB57 RS14230
gene id: 1715806:AOB57_RS14230
uniprot id: A0A660HVR4
names: Similarity
messages: Belongs to the peptidase S8 family.

1715806:AOB57 RS10570
gene id: 1715806:AOB57_RS10570
uniprot id: A0A660HTK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS09350
gene id: 1715806:AOB57_RS09350
uniprot id: A0A660HSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrC family.
messages: Cell membrane
messages: Membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

1715806:AOB57 RS05545
gene id: 1715806:AOB57_RS05545
uniprot id: A0A660HR12
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS00180
gene id: 1715806:AOB57_RS00180
uniprot id: A0A660HNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1715806:AOB57 RS07310
gene id: 1715806:AOB57_RS07310
uniprot id: A0A660HS31
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS10665
gene id: 1715806:AOB57_RS10665
uniprot id: A0A660HTD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Binds 1 [3Fe-4S] cluster.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1715806:AOB57 RS03745
gene id: 1715806:AOB57_RS03745
uniprot id: A0A660HQ97
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of delta and gamma chains. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.

1715806:AOB57 RS09195
gene id: 1715806:AOB57_RS09195
uniprot id: A0A660HSV4
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS09525
gene id: 1715806:AOB57_RS09525
uniprot id: A0A660HSY4
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS12530
gene id: 1715806:AOB57_RS12530
uniprot id: A0A660HVN7
names: Similarity
messages: Belongs to the TlyA family.

1715806:AOB57 RS01630
gene id: 1715806:AOB57_RS01630
uniprot id: A0A660HVC7
names: Similarity
messages: Belongs to the pirin family.

1715806:AOB57 RS04375
gene id: 1715806:AOB57_RS04375
uniprot id: A0A660HQH6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

1715806:AOB57 RS00885
gene id: 1715806:AOB57_RS00885
uniprot id: A0A660HP09
names: Similarity
messages: Belongs to the malic enzymes family.

1715806:AOB57 RS03050
gene id: 1715806:AOB57_RS03050
uniprot id: A0A7K4AX50
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS07305
gene id: 1715806:AOB57_RS07305
uniprot id: A0A660HS24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
messages: Cytoplasm
messages: May catalyze the biosynthesis of dTMP using an unknown cosubstrate.
messages: Monomer.

1715806:AOB57 RS06290
gene id: 1715806:AOB57_RS06290
uniprot id: A0A660HRE1
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

1715806:AOB57 RS08710
gene id: 1715806:AOB57_RS08710
uniprot id: A0A660HSN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

1715806:AOB57 RS09445
gene id: 1715806:AOB57_RS09445
uniprot id: A0A660HT21
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1715806:AOB57 RS09780
gene id: 1715806:AOB57_RS09780
uniprot id: A0A660HVQ3
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1715806:AOB57 RS09240
gene id: 1715806:AOB57_RS09240
uniprot id: A0A660HT80
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1715806:AOB57 RS10590
gene id: 1715806:AOB57_RS10590
uniprot id: A0A660HTZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1715806:AOB57 RS05495
gene id: 1715806:AOB57_RS05495
uniprot id: A0A660HR26
names: Similarity
messages: Belongs to the Ahb/Nir family.

1715806:AOB57 RS10250
gene id: 1715806:AOB57_RS10250
uniprot id: A0A660HTD4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1715806:AOB57 RS05440
gene id: 1715806:AOB57_RS05440
uniprot id: A0A660HR14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

1715806:AOB57 RS03550
gene id: 1715806:AOB57_RS03550
uniprot id: A0A660HQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1715806:AOB57 RS09990
gene id: 1715806:AOB57_RS09990
uniprot id: A0A660HT98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS10555
gene id: 1715806:AOB57_RS10555
uniprot id: A0A660HTY4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1715806:AOB57 RS05790
gene id: 1715806:AOB57_RS05790
uniprot id: A0A660HR52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1715806:AOB57 RS05020
gene id: 1715806:AOB57_RS05020
uniprot id: A0A660HQS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

1715806:AOB57 RS11455
gene id: 1715806:AOB57_RS11455
uniprot id: A0A660HTW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

1715806:AOB57 RS14100
gene id: 1715806:AOB57_RS14100
uniprot id: A0A7K4ASY2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS00185
gene id: 1715806:AOB57_RS00185
uniprot id: A0A660HNI6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1715806:AOB57 RS08545
gene id: 1715806:AOB57_RS08545
uniprot id: A0A660HTQ4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1715806:AOB57 RS10045
gene id: 1715806:AOB57_RS10045
uniprot id: A0A660HTN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

1715806:AOB57 RS07155
gene id: 1715806:AOB57_RS07155
uniprot id: A0A660HRV3
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1715806:AOB57 RS13590
gene id: 1715806:AOB57_RS13590
uniprot id: A0A660HUY5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1715806:AOB57 RS04805
gene id: 1715806:AOB57_RS04805
uniprot id: A0A660HQV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1715806:AOB57 RS09010
gene id: 1715806:AOB57_RS09010
uniprot id: A0A660HSS6
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1715806:AOB57 RS02550
gene id: 1715806:AOB57_RS02550
uniprot id: A0A660HVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1715806:AOB57 RS13600
gene id: 1715806:AOB57_RS13600
uniprot id: A0A660HVF3
names: Similarity
messages: Belongs to the UPF0280 family.

1715806:AOB57 RS04670
gene id: 1715806:AOB57_RS04670
uniprot id: A0A660HVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1715806:AOB57 RS02650
gene id: 1715806:AOB57_RS02650
uniprot id: A0A660HPU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1715806:AOB57 RS05410
gene id: 1715806:AOB57_RS05410
uniprot id: A0A660HR55
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1715806:AOB57 RS03915
gene id: 1715806:AOB57_RS03915
uniprot id: A0A660HQE9
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS00730
gene id: 1715806:AOB57_RS00730
uniprot id: A0A660HNS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1715806:AOB57 RS06160
gene id: 1715806:AOB57_RS06160
uniprot id: A0A660HRC5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1715806:AOB57 RS05345
gene id: 1715806:AOB57_RS05345
uniprot id: A0A660HR47
names: Similarity
messages: Belongs to the MEMO1 family.

1715806:AOB57 RS02690
gene id: 1715806:AOB57_RS02690
uniprot id: A0A660HQ46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1715806:AOB57 RS09835
gene id: 1715806:AOB57_RS09835
uniprot id: A0A660HT26
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1715806:AOB57 RS13735
gene id: 1715806:AOB57_RS13735
uniprot id: A0A660HUS2
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS07100
gene id: 1715806:AOB57_RS07100
uniprot id: A0A660HSE4
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS12970
gene id: 1715806:AOB57_RS12970
uniprot id: A0A660HVV3
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1715806:AOB57 RS11050
gene id: 1715806:AOB57_RS11050
uniprot id: A0A660HTL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1715806:AOB57 RS00330
gene id: 1715806:AOB57_RS00330
uniprot id: A0A660HNL0
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1715806:AOB57 RS05565
gene id: 1715806:AOB57_RS05565
uniprot id: A0A660HR33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1715806:AOB57 RS05085
gene id: 1715806:AOB57_RS05085
uniprot id: A0A660HRE6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1715806:AOB57 RS07045
gene id: 1715806:AOB57_RS07045
uniprot id: A0A660HRW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1715806:AOB57 RS09180
gene id: 1715806:AOB57_RS09180
uniprot id: A0A660HSR0
names: Similarity
messages: Belongs to the HerA family.

1715806:AOB57 RS08230
gene id: 1715806:AOB57_RS08230
uniprot id: A0A660HSG6
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1715806:AOB57 RS06085
gene id: 1715806:AOB57_RS06085
uniprot id: A0A660HRX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1715806:AOB57 RS12325
gene id: 1715806:AOB57_RS12325
uniprot id: A0A660HVJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1715806:AOB57 RS11155
gene id: 1715806:AOB57_RS11155
uniprot id: A0A660HUZ6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1715806:AOB57 RS03390
gene id: 1715806:AOB57_RS03390
uniprot id: A0A660HQ15
names: Similarity
messages: Belongs to the NAD synthetase family.

1715806:AOB57 RS09670
gene id: 1715806:AOB57_RS09670
uniprot id: A0A660HVX7
names: Similarity
messages: Belongs to the catalase family.

1715806:AOB57 RS08850
gene id: 1715806:AOB57_RS08850
uniprot id: A0A660HSN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

1715806:AOB57 RS03455
gene id: 1715806:AOB57_RS03455
uniprot id: A0A660HQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1715806:AOB57 RS08630
gene id: 1715806:AOB57_RS08630
uniprot id: A0A660HSI5
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1715806:AOB57 RS04615
gene id: 1715806:AOB57_RS04615
uniprot id: A0A7K4AWB5
names: Caution
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1715806:AOB57 RS01565
gene id: 1715806:AOB57_RS01565
uniprot id: A0A660HP82
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1715806:AOB57 RS03445
gene id: 1715806:AOB57_RS03445
uniprot id: A0A660HQ45
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

1715806:AOB57 RS12750
gene id: 1715806:AOB57_RS12750
uniprot id: A0A660HUA9
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS00305
gene id: 1715806:AOB57_RS00305
uniprot id: A0A660HP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS08370
gene id: 1715806:AOB57_RS08370
uniprot id: A0A660HVQ2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1715806:AOB57 RS03145
gene id: 1715806:AOB57_RS03145
uniprot id: A0A660HQC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

1715806:AOB57 RS00740
gene id: 1715806:AOB57_RS00740
uniprot id: A0A660HNS8
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1715806:AOB57 RS14290
gene id: 1715806:AOB57_RS14290
uniprot id: A0A660HV53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS06480
gene id: 1715806:AOB57_RS06480
uniprot id: A0A660HRP1
names: Similarity
messages: Belongs to the peptidase S49 family.

1715806:AOB57 RS06765
gene id: 1715806:AOB57_RS06765
uniprot id: A0A660HW60
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1715806:AOB57 RS13400
gene id: 1715806:AOB57_RS13400
uniprot id: A0A660HUQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS05380
gene id: 1715806:AOB57_RS05380
uniprot id: A0A660HVG8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1715806:AOB57 RS00300
gene id: 1715806:AOB57_RS00300
uniprot id: A0A660HNK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS07190
gene id: 1715806:AOB57_RS07190
uniprot id: A0A660HRU0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1715806:AOB57 RS13260
gene id: 1715806:AOB57_RS13260
uniprot id: A0A660HUS3
names: Subcellular Location Annotation
messages: Cell membrane

1715806:AOB57 RS05800
gene id: 1715806:AOB57_RS05800
uniprot id: A0A660HR90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1715806:AOB57 RS05700
gene id: 1715806:AOB57_RS05700
uniprot id: A0A660HRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1715806:AOB57 RS02470
gene id: 1715806:AOB57_RS02470
uniprot id: A0A660HQ12
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS06585
gene id: 1715806:AOB57_RS06585
uniprot id: A0A660HRP8
names: Subcellular Location Annotation
messages: Cell membrane

1715806:AOB57 RS10880
gene id: 1715806:AOB57_RS10880
uniprot id: A0A660HTJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1715806:AOB57 RS06425
gene id: 1715806:AOB57_RS06425
uniprot id: A0A660HRN1
names: Similarity
messages: Belongs to the AAA ATPase family.

1715806:AOB57 RS12185
gene id: 1715806:AOB57_RS12185
uniprot id: A0A660HU13
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1715806:AOB57 RS04395
gene id: 1715806:AOB57_RS04395
uniprot id: A0A660HQZ8
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS00175
gene id: 1715806:AOB57_RS00175
uniprot id: A0A660HNI8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1715806:AOB57 RS03330
gene id: 1715806:AOB57_RS03330
uniprot id: A0A660HQ25
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

1715806:AOB57 RS13410
gene id: 1715806:AOB57_RS13410
uniprot id: A0A660HUM0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1715806:AOB57 RS06380
gene id: 1715806:AOB57_RS06380
uniprot id: A0A660HRM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1715806:AOB57 RS11825
gene id: 1715806:AOB57_RS11825
uniprot id: A0A660HU27
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1715806:AOB57 RS12650
gene id: 1715806:AOB57_RS12650
uniprot id: A0A660HUZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

1715806:AOB57 RS08060
gene id: 1715806:AOB57_RS08060
uniprot id: A0A660HS92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

1715806:AOB57 RS09925
gene id: 1715806:AOB57_RS09925
uniprot id: A0A660HT56
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS00600
gene id: 1715806:AOB57_RS00600
uniprot id: A0A660HNR0
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS03785
gene id: 1715806:AOB57_RS03785
uniprot id: A0A660HQ90
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1715806:AOB57 RS09175
gene id: 1715806:AOB57_RS09175
uniprot id: A0A660HVW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS13485
gene id: 1715806:AOB57_RS13485
uniprot id: A0A660HUY8
names: Similarity
messages: Belongs to the peptidase S1B family.

1715806:AOB57 RS03670
gene id: 1715806:AOB57_RS03670
uniprot id: A0A660HQ42
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1715806:AOB57 RS05485
gene id: 1715806:AOB57_RS05485
uniprot id: A0A660HRM3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1715806:AOB57 RS07245
gene id: 1715806:AOB57_RS07245
uniprot id: A0A660HRU9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

1715806:AOB57 RS12550
gene id: 1715806:AOB57_RS12550
uniprot id: A0A660HUC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1715806:AOB57 RS05765
gene id: 1715806:AOB57_RS05765
uniprot id: A0A660HR40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

1715806:AOB57 RS08160
gene id: 1715806:AOB57_RS08160
uniprot id: A0A660HSF4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1715806:AOB57 RS06810
gene id: 1715806:AOB57_RS06810
uniprot id: A0A660HRV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS06430
gene id: 1715806:AOB57_RS06430
uniprot id: A0A660HRL7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1715806:AOB57 RS07165
gene id: 1715806:AOB57_RS07165
uniprot id: A0A660HRY6
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS06205
gene id: 1715806:AOB57_RS06205
uniprot id: A0A660HRT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1715806:AOB57 RS12385
gene id: 1715806:AOB57_RS12385
uniprot id: A0A660HUW9
names: Similarity
messages: Belongs to the UPF0047 family.

1715806:AOB57 RS14075
gene id: 1715806:AOB57_RS14075
uniprot id: A0A660HV58
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS13490
gene id: 1715806:AOB57_RS13490
uniprot id: A0A660HW63
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1715806:AOB57 RS12055
gene id: 1715806:AOB57_RS12055
uniprot id: A0A660HVE7
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS06115
gene id: 1715806:AOB57_RS06115
uniprot id: A0A660HR97
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1715806:AOB57 RS04620
gene id: 1715806:AOB57_RS04620
uniprot id: A0A660HQL5
names: Similarity
messages: Belongs to the MCM family.

1715806:AOB57 RS11880
gene id: 1715806:AOB57_RS11880
uniprot id: A0A660HUL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1715806:AOB57 RS05755
gene id: 1715806:AOB57_RS05755
uniprot id: A0A660HRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1715806:AOB57 RS12645
gene id: 1715806:AOB57_RS12645
uniprot id: A0A660HVQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

1715806:AOB57 RS00565
gene id: 1715806:AOB57_RS00565
uniprot id: A0A660HNP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1715806:AOB57 RS09285
gene id: 1715806:AOB57_RS09285
uniprot id: A0A660HTD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1715806:AOB57 RS09860
gene id: 1715806:AOB57_RS09860
uniprot id: A0A660HWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1715806:AOB57 RS09895
gene id: 1715806:AOB57_RS09895
uniprot id: A0A660HT36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS12510
gene id: 1715806:AOB57_RS12510
uniprot id: A0A660HVU9
names: Subcellular Location Annotation
messages: Membrane

1715806:AOB57 RS06250
gene id: 1715806:AOB57_RS06250
uniprot id: A0A660HRG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1715806:AOB57 RS06770
gene id: 1715806:AOB57_RS06770
uniprot id: A0A660HSA0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

1715806:AOB57 RS03465
gene id: 1715806:AOB57_RS03465
uniprot id: A0A660HQ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT.
messages: Cytoplasm

1715806:AOB57 RS04355
gene id: 1715806:AOB57_RS04355
uniprot id: A0A660HQM7
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1715806:AOB57 RS09050
gene id: 1715806:AOB57_RS09050
uniprot id: A0A660HVI8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1715806:AOB57 RS06195
gene id: 1715806:AOB57_RS06195
uniprot id: A0A660HRG1
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

1715806:AOB57 RS05750
gene id: 1715806:AOB57_RS05750
uniprot id: A0A660HR66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS03045
gene id: 1715806:AOB57_RS03045
uniprot id: A0A660HPT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1715806:AOB57 RS04750
gene id: 1715806:AOB57_RS04750
uniprot id: A0A660HQQ7
names: Similarity
messages: Belongs to the eIF-2-alpha family.

1715806:AOB57 RS10795
gene id: 1715806:AOB57_RS10795
uniprot id: A0A660HTM8
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

1715806:AOB57 RS11665
gene id: 1715806:AOB57_RS11665
uniprot id: A0A660HTT5
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1715806:AOB57 RS08815
gene id: 1715806:AOB57_RS08815
uniprot id: A0A660HST4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1715806:AOB57 RS01315
gene id: 1715806:AOB57_RS01315
uniprot id: A0A660HP40
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1715806:AOB57 RS12025
gene id: 1715806:AOB57_RS12025
uniprot id: A0A660HUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

1715806:AOB57 RS09795
gene id: 1715806:AOB57_RS09795
uniprot id: A0A660HSY9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

1715806:AOB57 RS08805
gene id: 1715806:AOB57_RS08805
uniprot id: A0A660HSL2
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1715806:AOB57 RS00035
gene id: 1715806:AOB57_RS00035
uniprot id: A0A660HNG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
messages: Cytoplasm