1712410:BR63 RS15735
gene id: 1712410:BR63_RS15735
uniprot id: A0A7G6E684
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1712410:BR63 RS07065
gene id: 1712410:BR63_RS07065
uniprot id: A0A7G6E1Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1712410:BR63 RS01875
gene id: 1712410:BR63_RS01875
uniprot id: A0A7G6DZC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1712410:BR63 RS16675
gene id: 1712410:BR63_RS16675
uniprot id: A0A7G6E6Q0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1712410:BR63 RS12865
gene id: 1712410:BR63_RS12865
uniprot id: A0A7G6E4V8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1712410:BR63 RS02630
gene id: 1712410:BR63_RS02630
uniprot id: A0A7G6DZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS00810
gene id: 1712410:BR63_RS00810
uniprot id: A0A7G6DYT7
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1712410:BR63 RS01765
gene id: 1712410:BR63_RS01765
uniprot id: A0A7G6DZA3
names: Similarity
messages: Belongs to the YggT family.

1712410:BR63 RS07705
gene id: 1712410:BR63_RS07705
uniprot id: A0A7G6E2A0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS10185
gene id: 1712410:BR63_RS10185
uniprot id: A0A7G6E3I1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS12315
gene id: 1712410:BR63_RS12315
uniprot id: A0A7G6E4L0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1712410:BR63 RS01600
gene id: 1712410:BR63_RS01600
uniprot id: A0A7G6DZ74
names: Similarity
messages: Belongs to the EamA transporter family.

1712410:BR63 RS08490
gene id: 1712410:BR63_RS08490
uniprot id: A0A7G6E2P1
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS07230
gene id: 1712410:BR63_RS07230
uniprot id: A0A7G6E213
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1712410:BR63 RS05985
gene id: 1712410:BR63_RS05985
uniprot id: A0A7G6E1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1712410:BR63 RS15975
gene id: 1712410:BR63_RS15975
uniprot id: A0A7G6E6C8
names: Similarity
messages: Belongs to the class-I fumarase family.

1712410:BR63 RS02440
gene id: 1712410:BR63_RS02440
uniprot id: A0A7G6DZL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1712410:BR63 RS00735
gene id: 1712410:BR63_RS00735
uniprot id: A0A7G6DYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS07405
gene id: 1712410:BR63_RS07405
uniprot id: A0A7G6E8C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.

1712410:BR63 RS04400
gene id: 1712410:BR63_RS04400
uniprot id: A0A7G6E0L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1712410:BR63 RS06985
gene id: 1712410:BR63_RS06985
uniprot id: A0A7G6E1X1
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

1712410:BR63 RS10765
gene id: 1712410:BR63_RS10765
uniprot id: A0A7G6E3T5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1712410:BR63 RS11420
gene id: 1712410:BR63_RS11420
uniprot id: A0A7G6E453
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1712410:BR63 RS09460
gene id: 1712410:BR63_RS09460
uniprot id: A0A7G6E360
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1712410:BR63 RS18555
gene id: 1712410:BR63_RS18555
uniprot id: A0A7G6E7N0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1712410:BR63 RS17455
gene id: 1712410:BR63_RS17455
uniprot id: A0A7G6E726
names: Similarity
messages: Belongs to the GerABKA family.

1712410:BR63 RS11070
gene id: 1712410:BR63_RS11070
uniprot id: A0A7G6E3Z2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1712410:BR63 RS00505
gene id: 1712410:BR63_RS00505
uniprot id: A0A7G6DYN4
names: Similarity
messages: Belongs to the EamA transporter family.

1712410:BR63 RS05510
gene id: 1712410:BR63_RS05510
uniprot id: A0A7G6E157
names: Similarity
messages: Belongs to the Fur family.

1712410:BR63 RS14945
gene id: 1712410:BR63_RS14945
uniprot id: A0A7G6E5V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1712410:BR63 RS08955
gene id: 1712410:BR63_RS08955
uniprot id: A0A7G6E2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1712410:BR63 RS14275
gene id: 1712410:BR63_RS14275
uniprot id: A0A7G6E5J0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1712410:BR63 RS02300
gene id: 1712410:BR63_RS02300
uniprot id: A0A7G6DZJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1712410:BR63 RS11905
gene id: 1712410:BR63_RS11905
uniprot id: A0A7G6E4E2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1712410:BR63 RS04840
gene id: 1712410:BR63_RS04840
uniprot id: A0A7G6E0T6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1712410:BR63 RS06070
gene id: 1712410:BR63_RS06070
uniprot id: A0A7G6E1F8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1712410:BR63 RS08190
gene id: 1712410:BR63_RS08190
uniprot id: A0A7G6E8E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1712410:BR63 RS00455
gene id: 1712410:BR63_RS00455
uniprot id: A0A7G6DYM7
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS16210
gene id: 1712410:BR63_RS16210
uniprot id: A0A7G6E6G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1712410:BR63 RS08135
gene id: 1712410:BR63_RS08135
uniprot id: A0A7G6E2H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS18090
gene id: 1712410:BR63_RS18090
uniprot id: A0A7G6E7E2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS05925
gene id: 1712410:BR63_RS05925
uniprot id: A0A7G6E1D3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS06205
gene id: 1712410:BR63_RS06205
uniprot id: A0A7G6E1I3
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1712410:BR63 RS03215
gene id: 1712410:BR63_RS03215
uniprot id: A0A7G6E004
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1712410:BR63 RS11480
gene id: 1712410:BR63_RS11480
uniprot id: A0A7G6E463
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1712410:BR63 RS02510
gene id: 1712410:BR63_RS02510
uniprot id: A0A7G6DZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1712410:BR63 RS00445
gene id: 1712410:BR63_RS00445
uniprot id: A0A7G6DYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1712410:BR63 RS11645
gene id: 1712410:BR63_RS11645
uniprot id: A0A7G6E495
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1712410:BR63 RS09790
gene id: 1712410:BR63_RS09790
uniprot id: A0A7G6E3B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1712410:BR63 RS15010
gene id: 1712410:BR63_RS15010
uniprot id: A0A7G6E5W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1712410:BR63 RS06295
gene id: 1712410:BR63_RS06295
uniprot id: A0A7G6E1J9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1712410:BR63 RS12695
gene id: 1712410:BR63_RS12695
uniprot id: A0A7G6E4S8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1712410:BR63 RS07935
gene id: 1712410:BR63_RS07935
uniprot id: A0A7G6E2E0
names: Similarity
messages: Belongs to the UbiD family.

1712410:BR63 RS15385
gene id: 1712410:BR63_RS15385
uniprot id: A0A7G6E628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1712410:BR63 RS04120
gene id: 1712410:BR63_RS04120
uniprot id: A0A7G6E0G7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1712410:BR63 RS13600
gene id: 1712410:BR63_RS13600
uniprot id: A0A7G6E580
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS04870
gene id: 1712410:BR63_RS04870
uniprot id: A0A7G6E0U2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1712410:BR63 RS16060
gene id: 1712410:BR63_RS16060
uniprot id: A0A7G6E6E2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1712410:BR63 RS17295
gene id: 1712410:BR63_RS17295
uniprot id: A0A7G6E6Z7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1712410:BR63 RS09470
gene id: 1712410:BR63_RS09470
uniprot id: A0A7G6E362
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1712410:BR63 RS17340
gene id: 1712410:BR63_RS17340
uniprot id: A0A7G6E705
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1712410:BR63 RS15600
gene id: 1712410:BR63_RS15600
uniprot id: A0A7G6E659
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1712410:BR63 RS06225
gene id: 1712410:BR63_RS06225
uniprot id: A0A7G6E8B4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1712410:BR63 RS11945
gene id: 1712410:BR63_RS11945
uniprot id: A0A7G6E4F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

1712410:BR63 RS02940
gene id: 1712410:BR63_RS02940
uniprot id: A0A7G6DZV1
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1712410:BR63 RS10255
gene id: 1712410:BR63_RS10255
uniprot id: A0A7G6E3J5
names: Similarity
messages: Belongs to the LOG family.

1712410:BR63 RS00720
gene id: 1712410:BR63_RS00720
uniprot id: A0A7G6DYS1
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1712410:BR63 RS12405
gene id: 1712410:BR63_RS12405
uniprot id: A0A7G6E4M7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1712410:BR63 RS05970
gene id: 1712410:BR63_RS05970
uniprot id: A0A7G6E1E2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1712410:BR63 RS17070
gene id: 1712410:BR63_RS17070
uniprot id: A0A7G6E6W1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1712410:BR63 RS01200
gene id: 1712410:BR63_RS01200
uniprot id: A0A7G6DZ05
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1712410:BR63 RS11490
gene id: 1712410:BR63_RS11490
uniprot id: A0A7G6E465
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1712410:BR63 RS02330
gene id: 1712410:BR63_RS02330
uniprot id: A0A7G6DZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1712410:BR63 RS14830
gene id: 1712410:BR63_RS14830
uniprot id: A0A7G6E5T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1712410:BR63 RS18510
gene id: 1712410:BR63_RS18510
uniprot id: A0A7G6E7M2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS00670
gene id: 1712410:BR63_RS00670
uniprot id: A0A7G6DYR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1712410:BR63 RS05060
gene id: 1712410:BR63_RS05060
uniprot id: A0A7G6E0X7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS10250
gene id: 1712410:BR63_RS10250
uniprot id: A0A7G6E3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1712410:BR63 RS11985
gene id: 1712410:BR63_RS11985
uniprot id: A0A7G6E4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS05305
gene id: 1712410:BR63_RS05305
uniprot id: A0A7G6E123
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1712410:BR63 RS06175
gene id: 1712410:BR63_RS06175
uniprot id: A0A7G6E1H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1712410:BR63 RS18145
gene id: 1712410:BR63_RS18145
uniprot id: A0A7G6E7F3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1712410:BR63 RS02225
gene id: 1712410:BR63_RS02225
uniprot id: A0A7G6E858
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS14935
gene id: 1712410:BR63_RS14935
uniprot id: A0A7G6E5V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1712410:BR63 RS06195
gene id: 1712410:BR63_RS06195
uniprot id: A0A7G6E1I1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1712410:BR63 RS01585
gene id: 1712410:BR63_RS01585
uniprot id: A0A7G6DZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1712410:BR63 RS05045
gene id: 1712410:BR63_RS05045
uniprot id: A0A7G6E0X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1712410:BR63 RS00390
gene id: 1712410:BR63_RS00390
uniprot id: A0A7G6DYL4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS05135
gene id: 1712410:BR63_RS05135
uniprot id: A0A7G6E0Z0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1712410:BR63 RS12650
gene id: 1712410:BR63_RS12650
uniprot id: A0A7G6E8L7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1712410:BR63 RS06510
gene id: 1712410:BR63_RS06510
uniprot id: A0A7G6E1P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1712410:BR63 RS01935
gene id: 1712410:BR63_RS01935
uniprot id: A0A7G6DZD4
names: Similarity
messages: Belongs to the AOR/FOR family.

1712410:BR63 RS02705
gene id: 1712410:BR63_RS02705
uniprot id: A0A7G6DZQ9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1712410:BR63 RS06640
gene id: 1712410:BR63_RS06640
uniprot id: A0A7G6E1R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS15570
gene id: 1712410:BR63_RS15570
uniprot id: A0A7G6E654
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1712410:BR63 RS05640
gene id: 1712410:BR63_RS05640
uniprot id: A0A7G6E183
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS14895
gene id: 1712410:BR63_RS14895
uniprot id: A0A7G6E5U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1712410:BR63 RS06460
gene id: 1712410:BR63_RS06460
uniprot id: A0A7G6E1N1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1712410:BR63 RS17695
gene id: 1712410:BR63_RS17695
uniprot id: A0A7G6E769
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS07820
gene id: 1712410:BR63_RS07820
uniprot id: A0A7G6E2C0
names: Similarity
messages: Belongs to the UPF0045 family.

1712410:BR63 RS04820
gene id: 1712410:BR63_RS04820
uniprot id: A0A7G6E0T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1712410:BR63 RS17855
gene id: 1712410:BR63_RS17855
uniprot id: A0A7G6E799
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1712410:BR63 RS07550
gene id: 1712410:BR63_RS07550
uniprot id: A0A7G6E274
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1712410:BR63 RS06015
gene id: 1712410:BR63_RS06015
uniprot id: A0A7G6E1F0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1712410:BR63 RS13215
gene id: 1712410:BR63_RS13215
uniprot id: A0A7G6E514
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1712410:BR63 RS11165
gene id: 1712410:BR63_RS11165
uniprot id: A0A7G6E410
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1712410:BR63 RS10685
gene id: 1712410:BR63_RS10685
uniprot id: A0A7G6E3S1
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS02385
gene id: 1712410:BR63_RS02385
uniprot id: A0A7G6DZK8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1712410:BR63 RS17535
gene id: 1712410:BR63_RS17535
uniprot id: A0A7G6E740
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1712410:BR63 RS18350
gene id: 1712410:BR63_RS18350
uniprot id: A0A7G6E7J3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS14150
gene id: 1712410:BR63_RS14150
uniprot id: A0A7G6E5G9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1712410:BR63 RS00915
gene id: 1712410:BR63_RS00915
uniprot id: A0A7G6DYV2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1712410:BR63 RS04695
gene id: 1712410:BR63_RS04695
uniprot id: A0A7G6E0Q9
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1712410:BR63 RS11390
gene id: 1712410:BR63_RS11390
uniprot id: A0A7G6E448
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1712410:BR63 RS03860
gene id: 1712410:BR63_RS03860
uniprot id: A0A7G6E0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1712410:BR63 RS10695
gene id: 1712410:BR63_RS10695
uniprot id: A0A7G6E3S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1712410:BR63 RS13150
gene id: 1712410:BR63_RS13150
uniprot id: A0A7G6E503
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1712410:BR63 RS07615
gene id: 1712410:BR63_RS07615
uniprot id: A0A7G6E285
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1712410:BR63 RS17580
gene id: 1712410:BR63_RS17580
uniprot id: A0A7G6E747
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS06485
gene id: 1712410:BR63_RS06485
uniprot id: A0A7G6E1N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1712410:BR63 RS06380
gene id: 1712410:BR63_RS06380
uniprot id: A0A7G6E1L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

1712410:BR63 RS04095
gene id: 1712410:BR63_RS04095
uniprot id: A0A7G6E0G2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1712410:BR63 RS01345
gene id: 1712410:BR63_RS01345
uniprot id: A0A7G6DZ29
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS07665
gene id: 1712410:BR63_RS07665
uniprot id: A0A7G6E295
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS04760
gene id: 1712410:BR63_RS04760
uniprot id: A0A7G6E0S1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1712410:BR63 RS14735
gene id: 1712410:BR63_RS14735
uniprot id: A0A7G6E5R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1712410:BR63 RS15525
gene id: 1712410:BR63_RS15525
uniprot id: A0A7G6E651
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1712410:BR63 RS12760
gene id: 1712410:BR63_RS12760
uniprot id: A0A7G6E4T9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1712410:BR63 RS06010
gene id: 1712410:BR63_RS06010
uniprot id: A0A7G6E1E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1712410:BR63 RS12765
gene id: 1712410:BR63_RS12765
uniprot id: A0A7G6E4U0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1712410:BR63 RS14695
gene id: 1712410:BR63_RS14695
uniprot id: A0A7G6E5R2
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

1712410:BR63 RS14035
gene id: 1712410:BR63_RS14035
uniprot id: A0A7G6E5E8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1712410:BR63 RS15955
gene id: 1712410:BR63_RS15955
uniprot id: A0A7G6E6C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1712410:BR63 RS13015
gene id: 1712410:BR63_RS13015
uniprot id: A0A7G6E4Y1
names: Similarity
messages: Belongs to the peptidase S16 family.

1712410:BR63 RS02745
gene id: 1712410:BR63_RS02745
uniprot id: A0A7G6DZR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

1712410:BR63 RS14335
gene id: 1712410:BR63_RS14335
uniprot id: A0A7G6E5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1712410:BR63 RS14910
gene id: 1712410:BR63_RS14910
uniprot id: A0A7G6E5U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1712410:BR63 RS14990
gene id: 1712410:BR63_RS14990
uniprot id: A0A7G6E5W1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1712410:BR63 RS13950
gene id: 1712410:BR63_RS13950
uniprot id: A0A7G6E5D4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS17400
gene id: 1712410:BR63_RS17400
uniprot id: A0A7G6E715
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS07580
gene id: 1712410:BR63_RS07580
uniprot id: A0A7G6E280
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1712410:BR63 RS09840
gene id: 1712410:BR63_RS09840
uniprot id: A0A7G6E3C5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1712410:BR63 RS00710
gene id: 1712410:BR63_RS00710
uniprot id: A0A7G6DYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS05340
gene id: 1712410:BR63_RS05340
uniprot id: A0A7G6E129
names: Similarity
messages: Belongs to the DprA/Smf family.

1712410:BR63 RS12255
gene id: 1712410:BR63_RS12255
uniprot id: A0A7G6E4K1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1712410:BR63 RS18060
gene id: 1712410:BR63_RS18060
uniprot id: A0A7G6E7D5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS06965
gene id: 1712410:BR63_RS06965
uniprot id: A0A7G6E8C3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1712410:BR63 RS15025
gene id: 1712410:BR63_RS15025
uniprot id: A0A7G6E5W8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1712410:BR63 RS18005
gene id: 1712410:BR63_RS18005
uniprot id: A0A7G6E7C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS14840
gene id: 1712410:BR63_RS14840
uniprot id: A0A7G6E5T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1712410:BR63 RS05015
gene id: 1712410:BR63_RS05015
uniprot id: A0A7G6E0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1712410:BR63 RS05220
gene id: 1712410:BR63_RS05220
uniprot id: A0A7G6E106
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1712410:BR63 RS12790
gene id: 1712410:BR63_RS12790
uniprot id: A0A7G6E4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1712410:BR63 RS11035
gene id: 1712410:BR63_RS11035
uniprot id: A0A7G6E3Y5
names: Similarity
messages: Belongs to the PspA/IM30 family.

1712410:BR63 RS07900
gene id: 1712410:BR63_RS07900
uniprot id: A0A7G6E2D3
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1712410:BR63 RS18880
gene id: 1712410:BR63_RS18880
uniprot id: A0A7G6E7T8
names: Similarity
messages: Belongs to the ThiD family.

1712410:BR63 RS07980
gene id: 1712410:BR63_RS07980
uniprot id: A0A7G6E2E8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1712410:BR63 RS13010
gene id: 1712410:BR63_RS13010
uniprot id: A0A7G6E8L9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1712410:BR63 RS04175
gene id: 1712410:BR63_RS04175
uniprot id: A0A7G6E0H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1712410:BR63 RS04170
gene id: 1712410:BR63_RS04170
uniprot id: A0A7G6E0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1712410:BR63 RS03850
gene id: 1712410:BR63_RS03850
uniprot id: A0A7G6E0B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1712410:BR63 RS18205
gene id: 1712410:BR63_RS18205
uniprot id: A0A7G6E7G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS07650
gene id: 1712410:BR63_RS07650
uniprot id: A0A7G6E292
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS01945
gene id: 1712410:BR63_RS01945
uniprot id: A0A7G6DZD5
names: Similarity
messages: Belongs to the AOR/FOR family.

1712410:BR63 RS14015
gene id: 1712410:BR63_RS14015
uniprot id: A0A7G6E5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS06800
gene id: 1712410:BR63_RS06800
uniprot id: A0A7G6E1U4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1712410:BR63 RS05115
gene id: 1712410:BR63_RS05115
uniprot id: A0A7G6E0Y6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1712410:BR63 RS06305
gene id: 1712410:BR63_RS06305
uniprot id: A0A7G6E1K1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1712410:BR63 RS10735
gene id: 1712410:BR63_RS10735
uniprot id: A0A7G6E3S9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1712410:BR63 RS08090
gene id: 1712410:BR63_RS08090
uniprot id: A0A7G6E2H0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1712410:BR63 RS12345
gene id: 1712410:BR63_RS12345
uniprot id: A0A7G6E4L5
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS12555
gene id: 1712410:BR63_RS12555
uniprot id: A0A7G6E4Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

1712410:BR63 RS14905
gene id: 1712410:BR63_RS14905
uniprot id: A0A7G6E5U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1712410:BR63 RS18105
gene id: 1712410:BR63_RS18105
uniprot id: A0A7G6E7E5
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1712410:BR63 RS14075
gene id: 1712410:BR63_RS14075
uniprot id: A0A7G6E5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1712410:BR63 RS02105
gene id: 1712410:BR63_RS02105
uniprot id: A0A7G6DZG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS00440
gene id: 1712410:BR63_RS00440
uniprot id: A0A7G6DYM4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1712410:BR63 RS00815
gene id: 1712410:BR63_RS00815
uniprot id: A0A7G6DYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1712410:BR63 RS08170
gene id: 1712410:BR63_RS08170
uniprot id: A0A7G6E2I1
names: Similarity
messages: Belongs to the TrpC family.

1712410:BR63 RS06350
gene id: 1712410:BR63_RS06350
uniprot id: A0A7G6E1L0
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1712410:BR63 RS15140
gene id: 1712410:BR63_RS15140
uniprot id: A0A7G6E5Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1712410:BR63 RS14100
gene id: 1712410:BR63_RS14100
uniprot id: A0A7G6E5G1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1712410:BR63 RS05105
gene id: 1712410:BR63_RS05105
uniprot id: A0A7G6E8A2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS07905
gene id: 1712410:BR63_RS07905
uniprot id: A0A7G6E2D4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1712410:BR63 RS14405
gene id: 1712410:BR63_RS14405
uniprot id: A0A7G6E5L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1712410:BR63 RS19040
gene id: 1712410:BR63_RS19040
uniprot id: A0A7G6E7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS15040
gene id: 1712410:BR63_RS15040
uniprot id: A0A7G6E5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1712410:BR63 RS04705
gene id: 1712410:BR63_RS04705
uniprot id: A0A7G6E0R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1712410:BR63 RS03970
gene id: 1712410:BR63_RS03970
uniprot id: A0A7G6E0D9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1712410:BR63 RS18030
gene id: 1712410:BR63_RS18030
uniprot id: A0A7G6E7D0
names: Similarity
messages: Belongs to the DltD family.

1712410:BR63 RS05100
gene id: 1712410:BR63_RS05100
uniprot id: A0A7G6E0Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1712410:BR63 RS18840
gene id: 1712410:BR63_RS18840
uniprot id: A0A7G6E7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1712410:BR63 RS15925
gene id: 1712410:BR63_RS15925
uniprot id: A0A7G6E6B8
names: Similarity
messages: Belongs to the PrpD family.

1712410:BR63 RS10200
gene id: 1712410:BR63_RS10200
uniprot id: A0A7G6E3I4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS10290
gene id: 1712410:BR63_RS10290
uniprot id: A0A7G6E3K2
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS10470
gene id: 1712410:BR63_RS10470
uniprot id: A0A7G6E3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1712410:BR63 RS00640
gene id: 1712410:BR63_RS00640
uniprot id: A0A7G6DYQ6
names: Similarity
messages: Belongs to the asparagine synthetase family.

1712410:BR63 RS04715
gene id: 1712410:BR63_RS04715
uniprot id: A0A7G6E0R3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1712410:BR63 RS05075
gene id: 1712410:BR63_RS05075
uniprot id: A0A7G6E0X9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS01560
gene id: 1712410:BR63_RS01560
uniprot id: A0A7G6DZ66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1712410:BR63 RS06830
gene id: 1712410:BR63_RS06830
uniprot id: A0A7G6E1V0
names: Similarity
messages: Belongs to the UPF0237 family.

1712410:BR63 RS08375
gene id: 1712410:BR63_RS08375
uniprot id: A0A7G6E2L9
names: Similarity
messages: Belongs to the CdaR family.

1712410:BR63 RS17575
gene id: 1712410:BR63_RS17575
uniprot id: A0A7G6E746
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS04980
gene id: 1712410:BR63_RS04980
uniprot id: A0A7G6E0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1712410:BR63 RS15720
gene id: 1712410:BR63_RS15720
uniprot id: A0A7G6E681
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1712410:BR63 RS06860
gene id: 1712410:BR63_RS06860
uniprot id: A0A7G6E1V4
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1712410:BR63 RS09340
gene id: 1712410:BR63_RS09340
uniprot id: A0A7G6E8G3
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS04015
gene id: 1712410:BR63_RS04015
uniprot id: A0A7G6E0E7
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS05750
gene id: 1712410:BR63_RS05750
uniprot id: A0A7G6E1A4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1712410:BR63 RS05940
gene id: 1712410:BR63_RS05940
uniprot id: A0A7G6E1D6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1712410:BR63 RS15835
gene id: 1712410:BR63_RS15835
uniprot id: A0A7G6E6A3
names: Similarity
messages: Belongs to the UxaA family.

1712410:BR63 RS13610
gene id: 1712410:BR63_RS13610
uniprot id: A0A7G6E582
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS07365
gene id: 1712410:BR63_RS07365
uniprot id: A0A7G6E239
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1712410:BR63 RS04000
gene id: 1712410:BR63_RS04000
uniprot id: A0A7G6E0E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1712410:BR63 RS09875
gene id: 1712410:BR63_RS09875
uniprot id: A0A7G6E3D1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS13535
gene id: 1712410:BR63_RS13535
uniprot id: A0A7G6E568
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1712410:BR63 RS15965
gene id: 1712410:BR63_RS15965
uniprot id: A0A7G6E6C6
names: Similarity
messages: Belongs to the UPF0173 family.

1712410:BR63 RS14890
gene id: 1712410:BR63_RS14890
uniprot id: A0A7G6E5U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1712410:BR63 RS08705
gene id: 1712410:BR63_RS08705
uniprot id: A0A7G6E2T1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1712410:BR63 RS07500
gene id: 1712410:BR63_RS07500
uniprot id: A0A7G6E264
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS03390
gene id: 1712410:BR63_RS03390
uniprot id: A0A7G6E037
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1712410:BR63 RS08750
gene id: 1712410:BR63_RS08750
uniprot id: A0A7G6E2T8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS05175
gene id: 1712410:BR63_RS05175
uniprot id: A0A7G6E0Z7
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1712410:BR63 RS11570
gene id: 1712410:BR63_RS11570
uniprot id: A0A7G6E481
names: Similarity
messages: Belongs to the peptidase S41A family.

1712410:BR63 RS00935
gene id: 1712410:BR63_RS00935
uniprot id: A0A7G6DYV6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1712410:BR63 RS09670
gene id: 1712410:BR63_RS09670
uniprot id: A0A7G6E396
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1712410:BR63 RS10160
gene id: 1712410:BR63_RS10160
uniprot id: A0A7G6E3H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS07515
gene id: 1712410:BR63_RS07515
uniprot id: A0A7G6E267
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS01100
gene id: 1712410:BR63_RS01100
uniprot id: A0A7G6DYY6
names: Similarity
messages: Belongs to the CdaR family.

1712410:BR63 RS16265
gene id: 1712410:BR63_RS16265
uniprot id: A0A7G6E6H3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1712410:BR63 RS01305
gene id: 1712410:BR63_RS01305
uniprot id: A0A7G6DZ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

1712410:BR63 RS06210
gene id: 1712410:BR63_RS06210
uniprot id: A0A7G6E1I4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS00925
gene id: 1712410:BR63_RS00925
uniprot id: A0A7G6DYV4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1712410:BR63 RS04655
gene id: 1712410:BR63_RS04655
uniprot id: A0A7G6E0Q2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1712410:BR63 RS15530
gene id: 1712410:BR63_RS15530
uniprot id: A0A7G6E652
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1712410:BR63 RS15725
gene id: 1712410:BR63_RS15725
uniprot id: A0A7G6E682
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1712410:BR63 RS10020
gene id: 1712410:BR63_RS10020
uniprot id: A0A7G6E3F6
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS16450
gene id: 1712410:BR63_RS16450
uniprot id: A0A7G6E6K8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1712410:BR63 RS02530
gene id: 1712410:BR63_RS02530
uniprot id: A0A7G6DZM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1712410:BR63 RS09025
gene id: 1712410:BR63_RS09025
uniprot id: A0A7G6E2Y4
names: Similarity
messages: Belongs to the UPF0751 family.

1712410:BR63 RS08160
gene id: 1712410:BR63_RS08160
uniprot id: A0A7G6E8E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1712410:BR63 RS12815
gene id: 1712410:BR63_RS12815
uniprot id: A0A7G6E4V0
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS12415
gene id: 1712410:BR63_RS12415
uniprot id: A0A7G6E4M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS06465
gene id: 1712410:BR63_RS06465
uniprot id: A0A7G6E1N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1712410:BR63 RS17670
gene id: 1712410:BR63_RS17670
uniprot id: A0A7G6E765
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Homodimer.

1712410:BR63 RS07660
gene id: 1712410:BR63_RS07660
uniprot id: A0A7G6E294
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1712410:BR63 RS17820
gene id: 1712410:BR63_RS17820
uniprot id: A0A7G6E792
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1712410:BR63 RS10450
gene id: 1712410:BR63_RS10450
uniprot id: A0A7G6E3N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1712410:BR63 RS10535
gene id: 1712410:BR63_RS10535
uniprot id: A0A7G6E3P4
names: Similarity
messages: Belongs to the HdrA family.

1712410:BR63 RS01750
gene id: 1712410:BR63_RS01750
uniprot id: A0A7G6DZA1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1712410:BR63 RS14815
gene id: 1712410:BR63_RS14815
uniprot id: A0A7G6E5S7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1712410:BR63 RS04310
gene id: 1712410:BR63_RS04310
uniprot id: A0A7G6E0K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS10650
gene id: 1712410:BR63_RS10650
uniprot id: A0A7G6E3R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1712410:BR63 RS14940
gene id: 1712410:BR63_RS14940
uniprot id: A0A7G6E5V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1712410:BR63 RS12835
gene id: 1712410:BR63_RS12835
uniprot id: A0A7G6E4V4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1712410:BR63 RS09565
gene id: 1712410:BR63_RS09565
uniprot id: A0A7G6E378
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1712410:BR63 RS15635
gene id: 1712410:BR63_RS15635
uniprot id: A0A7G6E666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1712410:BR63 RS08515
gene id: 1712410:BR63_RS08515
uniprot id: A0A7G6E2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1712410:BR63 RS08380
gene id: 1712410:BR63_RS08380
uniprot id: A0A7G6E2M0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS16225
gene id: 1712410:BR63_RS16225
uniprot id: A0A7G6E6G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1712410:BR63 RS06615
gene id: 1712410:BR63_RS06615
uniprot id: A0A7G6E1R0
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS16270
gene id: 1712410:BR63_RS16270
uniprot id: A0A7G6E6H4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1712410:BR63 RS10575
gene id: 1712410:BR63_RS10575
uniprot id: A0A7G6E3Q1
names: Similarity
messages: Belongs to the HupF/HypC family.

1712410:BR63 RS05310
gene id: 1712410:BR63_RS05310
uniprot id: A0A7G6E124
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1712410:BR63 RS14370
gene id: 1712410:BR63_RS14370
uniprot id: A0A7G6E5K7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1712410:BR63 RS15875
gene id: 1712410:BR63_RS15875
uniprot id: A0A7G6E6B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS02365
gene id: 1712410:BR63_RS02365
uniprot id: A0A7G6DZK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1712410:BR63 RS11125
gene id: 1712410:BR63_RS11125
uniprot id: A0A7G6E403
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1712410:BR63 RS04730
gene id: 1712410:BR63_RS04730
uniprot id: A0A7G6E0R6
names: Similarity
messages: Belongs to the CobH/CbiC family.

1712410:BR63 RS06115
gene id: 1712410:BR63_RS06115
uniprot id: A0A7G6E1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1712410:BR63 RS07025
gene id: 1712410:BR63_RS07025
uniprot id: A0A7G6E1X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1712410:BR63 RS04065
gene id: 1712410:BR63_RS04065
uniprot id: A0A7G6E0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS11145
gene id: 1712410:BR63_RS11145
uniprot id: A0A7G6E407
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1712410:BR63 RS08710
gene id: 1712410:BR63_RS08710
uniprot id: A0A7G6E2T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1712410:BR63 RS08350
gene id: 1712410:BR63_RS08350
uniprot id: A0A7G6E2L4
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS00665
gene id: 1712410:BR63_RS00665
uniprot id: A0A7G6DYR1
names: Similarity
messages: Belongs to the UPF0166 family.

1712410:BR63 RS09065
gene id: 1712410:BR63_RS09065
uniprot id: A0A7G6E2Z2
names: Similarity
messages: Belongs to the Fur family.

1712410:BR63 RS17490
gene id: 1712410:BR63_RS17490
uniprot id: A0A7G6E733
names: Similarity
messages: Belongs to the class-I fumarase family.

1712410:BR63 RS13715
gene id: 1712410:BR63_RS13715
uniprot id: A0A7G6E595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1712410:BR63 RS17765
gene id: 1712410:BR63_RS17765
uniprot id: A0A7G6E782
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1712410:BR63 RS02415
gene id: 1712410:BR63_RS02415
uniprot id: A0A7G6DZL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1712410:BR63 RS15770
gene id: 1712410:BR63_RS15770
uniprot id: A0A7G6E691
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS15730
gene id: 1712410:BR63_RS15730
uniprot id: A0A7G6E683
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1712410:BR63 RS06120
gene id: 1712410:BR63_RS06120
uniprot id: A0A7G6E1G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1712410:BR63 RS09390
gene id: 1712410:BR63_RS09390
uniprot id: A0A7G6E348
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1712410:BR63 RS12360
gene id: 1712410:BR63_RS12360
uniprot id: A0A7G6E4L8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1712410:BR63 RS17045
gene id: 1712410:BR63_RS17045
uniprot id: A0A7G6E6V8
names: Subcellular Location Annotation
messages: Cytoplasm

1712410:BR63 RS06690
gene id: 1712410:BR63_RS06690
uniprot id: A0A7G6E1S4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1712410:BR63 RS11610
gene id: 1712410:BR63_RS11610
uniprot id: A0A7G6E489
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1712410:BR63 RS19205
gene id: 1712410:BR63_RS19205
uniprot id: A0A7G6E7Z7
names: Similarity
messages: Belongs to the peptidase S14 family.

1712410:BR63 RS15020
gene id: 1712410:BR63_RS15020
uniprot id: A0A7G6E5W7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1712410:BR63 RS08930
gene id: 1712410:BR63_RS08930
uniprot id: A0A7G6E2W6
names: Similarity
messages: Belongs to the EamA transporter family.

1712410:BR63 RS14205
gene id: 1712410:BR63_RS14205
uniprot id: A0A7G6E5H8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS08725
gene id: 1712410:BR63_RS08725
uniprot id: A0A7G6E2T5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1712410:BR63 RS12900
gene id: 1712410:BR63_RS12900
uniprot id: A0A7G6E4W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1712410:BR63 RS04625
gene id: 1712410:BR63_RS04625
uniprot id: A0A7G6E0P7
names: Similarity
messages: Belongs to the histone deacetylase family.

1712410:BR63 RS10165
gene id: 1712410:BR63_RS10165
uniprot id: A0A7G6E3H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1712410:BR63 RS12785
gene id: 1712410:BR63_RS12785
uniprot id: A0A7G6E4U4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1712410:BR63 RS07320
gene id: 1712410:BR63_RS07320
uniprot id: A0A7G6E230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1712410:BR63 RS13575
gene id: 1712410:BR63_RS13575
uniprot id: A0A7G6E575
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1712410:BR63 RS07275
gene id: 1712410:BR63_RS07275
uniprot id: A0A7G6E222
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1712410:BR63 RS07020
gene id: 1712410:BR63_RS07020
uniprot id: A0A7G6E1X8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS05575
gene id: 1712410:BR63_RS05575
uniprot id: A0A7G6E170
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1712410:BR63 RS08035
gene id: 1712410:BR63_RS08035
uniprot id: A0A7G6E2F9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1712410:BR63 RS02700
gene id: 1712410:BR63_RS02700
uniprot id: A0A7G6DZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1712410:BR63 RS14720
gene id: 1712410:BR63_RS14720
uniprot id: A0A7G6E8P9
names: Similarity
messages: Belongs to the ycf81 family.

1712410:BR63 RS11735
gene id: 1712410:BR63_RS11735
uniprot id: A0A7G6E4B0
names: Similarity
messages: Belongs to the FlgM family.

1712410:BR63 RS09910
gene id: 1712410:BR63_RS09910
uniprot id: A0A7G6E8H7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1712410:BR63 RS10220
gene id: 1712410:BR63_RS10220
uniprot id: A0A7G6E3I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1712410:BR63 RS16290
gene id: 1712410:BR63_RS16290
uniprot id: A0A7G6E6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1712410:BR63 RS18825
gene id: 1712410:BR63_RS18825
uniprot id: A0A7G6E7S7
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS17715
gene id: 1712410:BR63_RS17715
uniprot id: A0A7G6E773
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS14600
gene id: 1712410:BR63_RS14600
uniprot id: A0A7G6E5P8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1712410:BR63 RS19020
gene id: 1712410:BR63_RS19020
uniprot id: A0A7G6E7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS11510
gene id: 1712410:BR63_RS11510
uniprot id: A0A7G6E469
names: Similarity
messages: Belongs to the peptidase S66 family.

1712410:BR63 RS00835
gene id: 1712410:BR63_RS00835
uniprot id: A0A7G6DYU2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1712410:BR63 RS04370
gene id: 1712410:BR63_RS04370
uniprot id: A0A7G6E0L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1712410:BR63 RS19030
gene id: 1712410:BR63_RS19030
uniprot id: A0A7G6E7W6
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS01620
gene id: 1712410:BR63_RS01620
uniprot id: A0A7G6DZ78
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1712410:BR63 RS12720
gene id: 1712410:BR63_RS12720
uniprot id: A0A7G6E4T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1712410:BR63 RS13480
gene id: 1712410:BR63_RS13480
uniprot id: A0A7G6E559
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1712410:BR63 RS13020
gene id: 1712410:BR63_RS13020
uniprot id: A0A7G6E4Y2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1712410:BR63 RS03120
gene id: 1712410:BR63_RS03120
uniprot id: A0A7G6DZY5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1712410:BR63 RS05600
gene id: 1712410:BR63_RS05600
uniprot id: A0A7G6E175
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1712410:BR63 RS13890
gene id: 1712410:BR63_RS13890
uniprot id: A0A7G6E5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1712410:BR63 RS07455
gene id: 1712410:BR63_RS07455
uniprot id: A0A7G6E256
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1712410:BR63 RS17010
gene id: 1712410:BR63_RS17010
uniprot id: A0A7G6E6V3
names: Similarity
messages: Belongs to the PspA/IM30 family.

1712410:BR63 RS01740
gene id: 1712410:BR63_RS01740
uniprot id: A0A7G6DZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1712410:BR63 RS10775
gene id: 1712410:BR63_RS10775
uniprot id: A0A7G6E3T7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1712410:BR63 RS10430
gene id: 1712410:BR63_RS10430
uniprot id: A0A7G6E3M6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1712410:BR63 RS09475
gene id: 1712410:BR63_RS09475
uniprot id: A0A7G6E363
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1712410:BR63 RS16100
gene id: 1712410:BR63_RS16100
uniprot id: A0A7G6E6F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1712410:BR63 RS04605
gene id: 1712410:BR63_RS04605
uniprot id: A0A7G6E0P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1712410:BR63 RS04665
gene id: 1712410:BR63_RS04665
uniprot id: A0A7G6E0Q4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1712410:BR63 RS08010
gene id: 1712410:BR63_RS08010
uniprot id: A0A7G6E2F4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1712410:BR63 RS11785
gene id: 1712410:BR63_RS11785
uniprot id: A0A7G6E4B8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS07805
gene id: 1712410:BR63_RS07805
uniprot id: A0A7G6E2B7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1712410:BR63 RS01880
gene id: 1712410:BR63_RS01880
uniprot id: A0A7G6DZC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1712410:BR63 RS08215
gene id: 1712410:BR63_RS08215
uniprot id: A0A7G6E2I9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1712410:BR63 RS04850
gene id: 1712410:BR63_RS04850
uniprot id: A0A7G6E0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1712410:BR63 RS11720
gene id: 1712410:BR63_RS11720
uniprot id: A0A7G6E4A7
names: Similarity
messages: Belongs to the bacterial flagellin family.

1712410:BR63 RS12750
gene id: 1712410:BR63_RS12750
uniprot id: A0A7G6E4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1712410:BR63 RS04360
gene id: 1712410:BR63_RS04360
uniprot id: A0A7G6E0K9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1712410:BR63 RS01730
gene id: 1712410:BR63_RS01730
uniprot id: A0A7G6DZ97
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1712410:BR63 RS12680
gene id: 1712410:BR63_RS12680
uniprot id: A0A7G6E4S5
names: Similarity
messages: Belongs to the FemABX family.

1712410:BR63 RS08175
gene id: 1712410:BR63_RS08175
uniprot id: A0A7G6E2I2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS14115
gene id: 1712410:BR63_RS14115
uniprot id: A0A7G6E5G4
names: Similarity
messages: Belongs to the glutamate synthase family.

1712410:BR63 RS07750
gene id: 1712410:BR63_RS07750
uniprot id: A0A7G6E2A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1712410:BR63 RS18790
gene id: 1712410:BR63_RS18790
uniprot id: A0A7G6E7S1
names: Similarity
messages: Belongs to the threonine synthase family.

1712410:BR63 RS08500
gene id: 1712410:BR63_RS08500
uniprot id: A0A7G6E2P3
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS14430
gene id: 1712410:BR63_RS14430
uniprot id: A0A7G6E5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1712410:BR63 RS10830
gene id: 1712410:BR63_RS10830
uniprot id: A0A7G6E3U8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1712410:BR63 RS00570
gene id: 1712410:BR63_RS00570
uniprot id: A0A7G6DYP3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1712410:BR63 RS02570
gene id: 1712410:BR63_RS02570
uniprot id: A0A7G6DZN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1712410:BR63 RS11080
gene id: 1712410:BR63_RS11080
uniprot id: A0A7G6E3Z4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1712410:BR63 RS08450
gene id: 1712410:BR63_RS08450
uniprot id: A0A7G6E2N4
names: Similarity
messages: Belongs to the AOR/FOR family.

1712410:BR63 RS05445
gene id: 1712410:BR63_RS05445
uniprot id: A0A7G6E147
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1712410:BR63 RS13160
gene id: 1712410:BR63_RS13160
uniprot id: A0A7G6E504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

1712410:BR63 RS08940
gene id: 1712410:BR63_RS08940
uniprot id: A0A7G6E2W8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS15005
gene id: 1712410:BR63_RS15005
uniprot id: A0A7G6E5W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1712410:BR63 RS18300
gene id: 1712410:BR63_RS18300
uniprot id: A0A7G6E7I3
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1712410:BR63 RS10240
gene id: 1712410:BR63_RS10240
uniprot id: A0A7G6E3J2
names: Similarity
messages: Belongs to the EamA transporter family.

1712410:BR63 RS12325
gene id: 1712410:BR63_RS12325
uniprot id: A0A7G6E8L0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1712410:BR63 RS14470
gene id: 1712410:BR63_RS14470
uniprot id: A0A7G6E5M4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS06065
gene id: 1712410:BR63_RS06065
uniprot id: A0A7G6E1F7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1712410:BR63 RS11705
gene id: 1712410:BR63_RS11705
uniprot id: A0A7G6E4A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1712410:BR63 RS04775
gene id: 1712410:BR63_RS04775
uniprot id: A0A7G6E0S4
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1712410:BR63 RS05035
gene id: 1712410:BR63_RS05035
uniprot id: A0A7G6E0X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1712410:BR63 RS13410
gene id: 1712410:BR63_RS13410
uniprot id: A0A7G6E547
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1712410:BR63 RS14185
gene id: 1712410:BR63_RS14185
uniprot id: A0A7G6E5H5
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1712410:BR63 RS02375
gene id: 1712410:BR63_RS02375
uniprot id: A0A7G6DZK6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS02680
gene id: 1712410:BR63_RS02680
uniprot id: A0A7G6DZQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS14835
gene id: 1712410:BR63_RS14835
uniprot id: A0A7G6E5T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1712410:BR63 RS14385
gene id: 1712410:BR63_RS14385
uniprot id: A0A7G6E5L0
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1712410:BR63 RS18835
gene id: 1712410:BR63_RS18835
uniprot id: A0A7G6E7S9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1712410:BR63 RS15055
gene id: 1712410:BR63_RS15055
uniprot id: A0A7G6E5X3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1712410:BR63 RS12685
gene id: 1712410:BR63_RS12685
uniprot id: A0A7G6E4S6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS05140
gene id: 1712410:BR63_RS05140
uniprot id: A0A7G6E8A3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1712410:BR63 RS05190
gene id: 1712410:BR63_RS05190
uniprot id: A0A7G6E100
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Role in flagellar biosynthesis.

1712410:BR63 RS02860
gene id: 1712410:BR63_RS02860
uniprot id: A0A7G6DZT9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1712410:BR63 RS07630
gene id: 1712410:BR63_RS07630
uniprot id: A0A7G6E288
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1712410:BR63 RS09495
gene id: 1712410:BR63_RS09495
uniprot id: A0A7G6E366
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1712410:BR63 RS15420
gene id: 1712410:BR63_RS15420
uniprot id: A0A7G6E635
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1712410:BR63 RS04685
gene id: 1712410:BR63_RS04685
uniprot id: A0A7G6E0Q7
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS07185
gene id: 1712410:BR63_RS07185
uniprot id: A0A7G6E206
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1712410:BR63 RS17280
gene id: 1712410:BR63_RS17280
uniprot id: A0A7G6E6Z4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1712410:BR63 RS16275
gene id: 1712410:BR63_RS16275
uniprot id: A0A7G6E6H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1712410:BR63 RS11865
gene id: 1712410:BR63_RS11865
uniprot id: A0A7G6E4D4
names: Similarity
messages: Belongs to the IlvD/Edd family.

1712410:BR63 RS17570
gene id: 1712410:BR63_RS17570
uniprot id: A0A7G6E745
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS08935
gene id: 1712410:BR63_RS08935
uniprot id: A0A7G6E2W7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1712410:BR63 RS08275
gene id: 1712410:BR63_RS08275
uniprot id: A0A7G6E2K0
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1712410:BR63 RS10465
gene id: 1712410:BR63_RS10465
uniprot id: A0A7G6E3N1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS07440
gene id: 1712410:BR63_RS07440
uniprot id: A0A7G6E253
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1712410:BR63 RS17655
gene id: 1712410:BR63_RS17655
uniprot id: A0A7G6E762
names: Similarity
messages: Belongs to the glutamine synthetase family.

1712410:BR63 RS14625
gene id: 1712410:BR63_RS14625
uniprot id: A0A7G6E5Q3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1712410:BR63 RS12610
gene id: 1712410:BR63_RS12610
uniprot id: A0A7G6E4R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS04430
gene id: 1712410:BR63_RS04430
uniprot id: A0A7G6E0M1
names: Similarity
messages: Belongs to the UxaA family.

1712410:BR63 RS02580
gene id: 1712410:BR63_RS02580
uniprot id: A0A7G6DZN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1712410:BR63 RS06135
gene id: 1712410:BR63_RS06135
uniprot id: A0A7G6E1H1
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1712410:BR63 RS00095
gene id: 1712410:BR63_RS00095
uniprot id: A0A7G6E817
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1712410:BR63 RS02290
gene id: 1712410:BR63_RS02290
uniprot id: A0A7G6DZJ0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1712410:BR63 RS06310
gene id: 1712410:BR63_RS06310
uniprot id: A0A7G6E1K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS10630
gene id: 1712410:BR63_RS10630
uniprot id: A0A7G6E3R1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1712410:BR63 RS00350
gene id: 1712410:BR63_RS00350
uniprot id: A0A7G6DYK6
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1712410:BR63 RS02785
gene id: 1712410:BR63_RS02785
uniprot id: A0A7G6DZS4
names: Similarity
messages: Belongs to the HdrA family.

1712410:BR63 RS17500
gene id: 1712410:BR63_RS17500
uniprot id: A0A7G6E735
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1712410:BR63 RS00580
gene id: 1712410:BR63_RS00580
uniprot id: A0A7G6DYP5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1712410:BR63 RS15485
gene id: 1712410:BR63_RS15485
uniprot id: A0A7G6E644
names: Similarity
messages: Belongs to the GerABKA family.

1712410:BR63 RS06245
gene id: 1712410:BR63_RS06245
uniprot id: A0A7G6E1I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1712410:BR63 RS13515
gene id: 1712410:BR63_RS13515
uniprot id: A0A7G6E565
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1712410:BR63 RS15270
gene id: 1712410:BR63_RS15270
uniprot id: A0A7G6E610
names: Similarity
messages: Belongs to the peptidase S8 family.

1712410:BR63 RS06435
gene id: 1712410:BR63_RS06435
uniprot id: A0A7G6E1M6
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS10295
gene id: 1712410:BR63_RS10295
uniprot id: A0A7G6E3K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1712410:BR63 RS14730
gene id: 1712410:BR63_RS14730
uniprot id: A0A7G6E5R7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS18395
gene id: 1712410:BR63_RS18395
uniprot id: A0A7G6E7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS16970
gene id: 1712410:BR63_RS16970
uniprot id: A0A7G6E6U6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1712410:BR63 RS10745
gene id: 1712410:BR63_RS10745
uniprot id: A0A7G6E3T1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1712410:BR63 RS11640
gene id: 1712410:BR63_RS11640
uniprot id: A0A7G6E494
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1712410:BR63 RS12870
gene id: 1712410:BR63_RS12870
uniprot id: A0A7G6E4V9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1712410:BR63 RS02560
gene id: 1712410:BR63_RS02560
uniprot id: A0A7G6E864
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1712410:BR63 RS13090
gene id: 1712410:BR63_RS13090
uniprot id: A0A7G6E4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

1712410:BR63 RS02720
gene id: 1712410:BR63_RS02720
uniprot id: A0A7G6DZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1712410:BR63 RS11760
gene id: 1712410:BR63_RS11760
uniprot id: A0A7G6E4B5
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS06735
gene id: 1712410:BR63_RS06735
uniprot id: A0A7G6E1T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1712410:BR63 RS16850
gene id: 1712410:BR63_RS16850
uniprot id: A0A7G6E6S9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1712410:BR63 RS14805
gene id: 1712410:BR63_RS14805
uniprot id: A0A7G6E5S5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1712410:BR63 RS07505
gene id: 1712410:BR63_RS07505
uniprot id: A0A7G6E265
names: Similarity
messages: Belongs to the HPA decarboxylase small subunit family.

1712410:BR63 RS13060
gene id: 1712410:BR63_RS13060
uniprot id: A0A7G6E4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1712410:BR63 RS18935
gene id: 1712410:BR63_RS18935
uniprot id: A0A7G6E7U7
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS06825
gene id: 1712410:BR63_RS06825
uniprot id: A0A7G6E1U9
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1712410:BR63 RS09545
gene id: 1712410:BR63_RS09545
uniprot id: A0A7G6E374
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1712410:BR63 RS04160
gene id: 1712410:BR63_RS04160
uniprot id: A0A7G6E0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS16415
gene id: 1712410:BR63_RS16415
uniprot id: A0A7G6E6K1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1712410:BR63 RS17470
gene id: 1712410:BR63_RS17470
uniprot id: A0A7G6E729
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS06390
gene id: 1712410:BR63_RS06390
uniprot id: A0A7G6E1L8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1712410:BR63 RS17480
gene id: 1712410:BR63_RS17480
uniprot id: A0A7G6E731
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1712410:BR63 RS02585
gene id: 1712410:BR63_RS02585
uniprot id: A0A7G6DZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1712410:BR63 RS19110
gene id: 1712410:BR63_RS19110
uniprot id: A0A7G6E7Y0
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1712410:BR63 RS03935
gene id: 1712410:BR63_RS03935
uniprot id: A0A7G6E0D3
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1712410:BR63 RS05860
gene id: 1712410:BR63_RS05860
uniprot id: A0A7G6E1C7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1712410:BR63 RS06360
gene id: 1712410:BR63_RS06360
uniprot id: A0A7G6E1L2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1712410:BR63 RS06270
gene id: 1712410:BR63_RS06270
uniprot id: A0A7G6E1J4
names: Similarity
messages: Belongs to the fabD family.

1712410:BR63 RS04165
gene id: 1712410:BR63_RS04165
uniprot id: A0A7G6E0H4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1712410:BR63 RS03140
gene id: 1712410:BR63_RS03140
uniprot id: A0A7G6DZY9
names: Similarity
messages: Belongs to the GSP E family.

1712410:BR63 RS16295
gene id: 1712410:BR63_RS16295
uniprot id: A0A7G6E6H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1712410:BR63 RS01510
gene id: 1712410:BR63_RS01510
uniprot id: A0A7G6DZ57
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1712410:BR63 RS12355
gene id: 1712410:BR63_RS12355
uniprot id: A0A7G6E4L7
names: Similarity
messages: Belongs to the intimin/invasin family.

1712410:BR63 RS05390
gene id: 1712410:BR63_RS05390
uniprot id: A0A7G6E138
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1712410:BR63 RS14145
gene id: 1712410:BR63_RS14145
uniprot id: A0A7G6E5G8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1712410:BR63 RS02880
gene id: 1712410:BR63_RS02880
uniprot id: A0A7G6DZU2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1712410:BR63 RS02445
gene id: 1712410:BR63_RS02445
uniprot id: A0A7G6DZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1712410:BR63 RS15185
gene id: 1712410:BR63_RS15185
uniprot id: A0A7G6E5Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS18690
gene id: 1712410:BR63_RS18690
uniprot id: A0A7G6E7Q3
names: Similarity
messages: Belongs to the Ahb/Nir family.

1712410:BR63 RS11445
gene id: 1712410:BR63_RS11445
uniprot id: A0A7G6E457
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1712410:BR63 RS06445
gene id: 1712410:BR63_RS06445
uniprot id: A0A7G6E1M8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1712410:BR63 RS01995
gene id: 1712410:BR63_RS01995
uniprot id: A0A7G6DZE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1712410:BR63 RS09480
gene id: 1712410:BR63_RS09480
uniprot id: A0A7G6E364
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1712410:BR63 RS10560
gene id: 1712410:BR63_RS10560
uniprot id: A0A7G6E3P9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1712410:BR63 RS00920
gene id: 1712410:BR63_RS00920
uniprot id: A0A7G6DYV3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1712410:BR63 RS07860
gene id: 1712410:BR63_RS07860
uniprot id: A0A7G6E2C7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1712410:BR63 RS00905
gene id: 1712410:BR63_RS00905
uniprot id: A0A7G6DYV0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1712410:BR63 RS02500
gene id: 1712410:BR63_RS02500
uniprot id: A0A7G6DZM5
names: Similarity
messages: Belongs to the UPF0145 family.

1712410:BR63 RS13585
gene id: 1712410:BR63_RS13585
uniprot id: A0A7G6E577
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1712410:BR63 RS13490
gene id: 1712410:BR63_RS13490
uniprot id: A0A7G6E561
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1712410:BR63 RS15580
gene id: 1712410:BR63_RS15580
uniprot id: A0A7G6E656
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1712410:BR63 RS07475
gene id: 1712410:BR63_RS07475
uniprot id: A0A7G6E260
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1712410:BR63 RS13590
gene id: 1712410:BR63_RS13590
uniprot id: A0A7G6E578
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1712410:BR63 RS03790
gene id: 1712410:BR63_RS03790
uniprot id: A0A7G6E0A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1712410:BR63 RS02650
gene id: 1712410:BR63_RS02650
uniprot id: A0A7G6DZP9
names: Similarity
messages: Belongs to the thioredoxin family.

1712410:BR63 RS15695
gene id: 1712410:BR63_RS15695
uniprot id: A0A7G6E677
names: Similarity
messages: Belongs to the UPF0758 family.

1712410:BR63 RS09705
gene id: 1712410:BR63_RS09705
uniprot id: A0A7G6E3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1712410:BR63 RS04315
gene id: 1712410:BR63_RS04315
uniprot id: A0A7G6E0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS15830
gene id: 1712410:BR63_RS15830
uniprot id: A0A7G6E6A2
names: Similarity
messages: Belongs to the KdgT transporter family.

1712410:BR63 RS16865
gene id: 1712410:BR63_RS16865
uniprot id: A0A7G6E6T2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1712410:BR63 RS04110
gene id: 1712410:BR63_RS04110
uniprot id: A0A7G6E0G5
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1712410:BR63 RS17485
gene id: 1712410:BR63_RS17485
uniprot id: A0A7G6E732
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1712410:BR63 RS14980
gene id: 1712410:BR63_RS14980
uniprot id: A0A7G6E5V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1712410:BR63 RS10935
gene id: 1712410:BR63_RS10935
uniprot id: A0A7G6E3W6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS14900
gene id: 1712410:BR63_RS14900
uniprot id: A0A7G6E5U3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1712410:BR63 RS15015
gene id: 1712410:BR63_RS15015
uniprot id: A0A7G6E5W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1712410:BR63 RS01335
gene id: 1712410:BR63_RS01335
uniprot id: A0A7G6DZ27
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1712410:BR63 RS08260
gene id: 1712410:BR63_RS08260
uniprot id: A0A7G6E2J7
names: Similarity
messages: Belongs to the EamA transporter family.

1712410:BR63 RS10780
gene id: 1712410:BR63_RS10780
uniprot id: A0A7G6E3T8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1712410:BR63 RS11105
gene id: 1712410:BR63_RS11105
uniprot id: A0A7G6E3Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1712410:BR63 RS09945
gene id: 1712410:BR63_RS09945
uniprot id: A0A7G6E3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1712410:BR63 RS14970
gene id: 1712410:BR63_RS14970
uniprot id: A0A7G6E5V7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1712410:BR63 RS04845
gene id: 1712410:BR63_RS04845
uniprot id: A0A7G6E0T7
names: Similarity
messages: Belongs to the CinA family.

1712410:BR63 RS13710
gene id: 1712410:BR63_RS13710
uniprot id: A0A7G6E594
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS14070
gene id: 1712410:BR63_RS14070
uniprot id: A0A7G6E5F5
names: Similarity
messages: Belongs to the manganese catalase family.

1712410:BR63 RS16300
gene id: 1712410:BR63_RS16300
uniprot id: A0A7G6E6I0
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1712410:BR63 RS06650
gene id: 1712410:BR63_RS06650
uniprot id: A0A7G6E1R6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1712410:BR63 RS11000
gene id: 1712410:BR63_RS11000
uniprot id: A0A7G6E3X8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS15400
gene id: 1712410:BR63_RS15400
uniprot id: A0A7G6E631
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1712410:BR63 RS01190
gene id: 1712410:BR63_RS01190
uniprot id: A0A7G6DZ03
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS06180
gene id: 1712410:BR63_RS06180
uniprot id: A0A7G6E1H8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1712410:BR63 RS02245
gene id: 1712410:BR63_RS02245
uniprot id: A0A7G6DZI1
names: Similarity
messages: Belongs to the SfsA family.

1712410:BR63 RS08040
gene id: 1712410:BR63_RS08040
uniprot id: A0A7G6E2G0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1712410:BR63 RS05225
gene id: 1712410:BR63_RS05225
uniprot id: A0A7G6E107
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1712410:BR63 RS08085
gene id: 1712410:BR63_RS08085
uniprot id: A0A7G6E2G9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1712410:BR63 RS05185
gene id: 1712410:BR63_RS05185
uniprot id: A0A7G6E0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1712410:BR63 RS07640
gene id: 1712410:BR63_RS07640
uniprot id: A0A7G6E290
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1712410:BR63 RS02265
gene id: 1712410:BR63_RS02265
uniprot id: A0A7G6DZI5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1712410:BR63 RS06395
gene id: 1712410:BR63_RS06395
uniprot id: A0A7G6E1L9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1712410:BR63 RS04045
gene id: 1712410:BR63_RS04045
uniprot id: A0A7G6E0F3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1712410:BR63 RS03990
gene id: 1712410:BR63_RS03990
uniprot id: A0A7G6E0E2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS08385
gene id: 1712410:BR63_RS08385
uniprot id: A0A7G6E2M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1712410:BR63 RS06160
gene id: 1712410:BR63_RS06160
uniprot id: A0A7G6E1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS15190
gene id: 1712410:BR63_RS15190
uniprot id: A0A7G6E5Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS07495
gene id: 1712410:BR63_RS07495
uniprot id: A0A7G6E8D0
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1712410:BR63 RS01055
gene id: 1712410:BR63_RS01055
uniprot id: A0A7G6DYX8
names: Similarity
messages: Belongs to the peptidase M24B family.

1712410:BR63 RS15980
gene id: 1712410:BR63_RS15980
uniprot id: A0A7G6E6C9
names: Similarity
messages: Belongs to the class-I fumarase family.

1712410:BR63 RS17615
gene id: 1712410:BR63_RS17615
uniprot id: A0A7G6E754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1712410:BR63 RS14310
gene id: 1712410:BR63_RS14310
uniprot id: A0A7G6E5J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1712410:BR63 RS02335
gene id: 1712410:BR63_RS02335
uniprot id: A0A7G6DZJ8
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS09395
gene id: 1712410:BR63_RS09395
uniprot id: A0A7G6E349
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1712410:BR63 RS15605
gene id: 1712410:BR63_RS15605
uniprot id: A0A7G6E660
names: Similarity
messages: Belongs to the EamA transporter family.

1712410:BR63 RS09505
gene id: 1712410:BR63_RS09505
uniprot id: A0A7G6E367
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS15715
gene id: 1712410:BR63_RS15715
uniprot id: A0A7G6E680
names: Similarity
messages: Belongs to the transpeptidase family.

1712410:BR63 RS03205
gene id: 1712410:BR63_RS03205
uniprot id: A0A7G6E002
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1712410:BR63 RS12565
gene id: 1712410:BR63_RS12565
uniprot id: A0A7G6E4Q6
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS14645
gene id: 1712410:BR63_RS14645
uniprot id: A0A7G6E5Q7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1712410:BR63 RS05345
gene id: 1712410:BR63_RS05345
uniprot id: A0A7G6E130
names: Similarity
messages: Belongs to the UPF0173 family.

1712410:BR63 RS13170
gene id: 1712410:BR63_RS13170
uniprot id: A0A7G6E506
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS09860
gene id: 1712410:BR63_RS09860
uniprot id: A0A7G6E3C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1712410:BR63 RS14620
gene id: 1712410:BR63_RS14620
uniprot id: A0A7G6E5Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS08990
gene id: 1712410:BR63_RS08990
uniprot id: A0A7G6E2X7
names: Similarity
messages: Belongs to the EamA transporter family.

1712410:BR63 RS06775
gene id: 1712410:BR63_RS06775
uniprot id: A0A7G6E1U0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS09045
gene id: 1712410:BR63_RS09045
uniprot id: A0A7G6E2Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1712410:BR63 RS14870
gene id: 1712410:BR63_RS14870
uniprot id: A0A7G6E5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1712410:BR63 RS00320
gene id: 1712410:BR63_RS00320
uniprot id: A0A7G6DYK1
names: Similarity
messages: Belongs to the PemK/MazF family.

1712410:BR63 RS07390
gene id: 1712410:BR63_RS07390
uniprot id: A0A7G6E244
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1712410:BR63 RS03840
gene id: 1712410:BR63_RS03840
uniprot id: A0A7G6E0B5
names: Similarity
messages: Belongs to the peptidase U62 family.

1712410:BR63 RS18565
gene id: 1712410:BR63_RS18565
uniprot id: A0A7G6E7N1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1712410:BR63 RS05005
gene id: 1712410:BR63_RS05005
uniprot id: A0A7G6E0W7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1712410:BR63 RS11880
gene id: 1712410:BR63_RS11880
uniprot id: A0A7G6E4D7
names: Similarity
messages: Belongs to the UxaA family.

1712410:BR63 RS05085
gene id: 1712410:BR63_RS05085
uniprot id: A0A7G6E0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1712410:BR63 RS12260
gene id: 1712410:BR63_RS12260
uniprot id: A0A7G6E4K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS02080
gene id: 1712410:BR63_RS02080
uniprot id: A0A7G6E852
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS11675
gene id: 1712410:BR63_RS11675
uniprot id: A0A7G6E4A1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS02315
gene id: 1712410:BR63_RS02315
uniprot id: A0A7G6DZJ4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS04830
gene id: 1712410:BR63_RS04830
uniprot id: A0A7G6E0T4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1712410:BR63 RS01780
gene id: 1712410:BR63_RS01780
uniprot id: A0A7G6E848
names: Similarity
messages: Belongs to the UPF0235 family.

1712410:BR63 RS14975
gene id: 1712410:BR63_RS14975
uniprot id: A0A7G6E5V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1712410:BR63 RS06250
gene id: 1712410:BR63_RS06250
uniprot id: A0A7G6E1J0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1712410:BR63 RS04200
gene id: 1712410:BR63_RS04200
uniprot id: A0A7G6E0I0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1712410:BR63 RS09635
gene id: 1712410:BR63_RS09635
uniprot id: A0A7G6E391
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1712410:BR63 RS05295
gene id: 1712410:BR63_RS05295
uniprot id: A0A7G6E121
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1712410:BR63 RS18045
gene id: 1712410:BR63_RS18045
uniprot id: A0A7G6E7D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

1712410:BR63 RS11085
gene id: 1712410:BR63_RS11085
uniprot id: A0A7G6E3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS09485
gene id: 1712410:BR63_RS09485
uniprot id: A0A7G6E365
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1712410:BR63 RS15045
gene id: 1712410:BR63_RS15045
uniprot id: A0A7G6E5X1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS10300
gene id: 1712410:BR63_RS10300
uniprot id: A0A7G6E3K4
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS04295
gene id: 1712410:BR63_RS04295
uniprot id: A0A7G6E0J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1712410:BR63 RS06525
gene id: 1712410:BR63_RS06525
uniprot id: A0A7G6E1P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1712410:BR63 RS17645
gene id: 1712410:BR63_RS17645
uniprot id: A0A7G6E760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1712410:BR63 RS19015
gene id: 1712410:BR63_RS19015
uniprot id: A0A7G6E7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS12660
gene id: 1712410:BR63_RS12660
uniprot id: A0A7G6E4S1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1712410:BR63 RS04235
gene id: 1712410:BR63_RS04235
uniprot id: A0A7G6E0I6
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

1712410:BR63 RS05990
gene id: 1712410:BR63_RS05990
uniprot id: A0A7G6E1E5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1712410:BR63 RS05000
gene id: 1712410:BR63_RS05000
uniprot id: A0A7G6E0W6
names: Similarity
messages: Belongs to the ribF family.

1712410:BR63 RS09610
gene id: 1712410:BR63_RS09610
uniprot id: A0A7G6E386
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS18095
gene id: 1712410:BR63_RS18095
uniprot id: A0A7G6E7E3
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1712410:BR63 RS18220
gene id: 1712410:BR63_RS18220
uniprot id: A0A7G6E7G8
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1712410:BR63 RS04825
gene id: 1712410:BR63_RS04825
uniprot id: A0A7G6E0T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1712410:BR63 RS11580
gene id: 1712410:BR63_RS11580
uniprot id: A0A7G6E483
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1712410:BR63 RS06220
gene id: 1712410:BR63_RS06220
uniprot id: A0A7G6E1I6
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1712410:BR63 RS15700
gene id: 1712410:BR63_RS15700
uniprot id: A0A7G6E8R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1712410:BR63 RS18855
gene id: 1712410:BR63_RS18855
uniprot id: A0A7G6E7T3
names: Caution
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS10090
gene id: 1712410:BR63_RS10090
uniprot id: A0A7G6E3G7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1712410:BR63 RS09335
gene id: 1712410:BR63_RS09335
uniprot id: A0A7G6E338
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS18665
gene id: 1712410:BR63_RS18665
uniprot id: A0A7G6E7Q0
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1712410:BR63 RS19060
gene id: 1712410:BR63_RS19060
uniprot id: A0A7G6E7X0
names: Similarity
messages: Belongs to the peptidase S24 family.

1712410:BR63 RS04965
gene id: 1712410:BR63_RS04965
uniprot id: A0A7G6E0V9
names: Similarity
messages: Belongs to the peptidase M16 family.

1712410:BR63 RS03955
gene id: 1712410:BR63_RS03955
uniprot id: A0A7G6E0D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1712410:BR63 RS06440
gene id: 1712410:BR63_RS06440
uniprot id: A0A7G6E1M7
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

1712410:BR63 RS13665
gene id: 1712410:BR63_RS13665
uniprot id: A0A7G6E587
names: Similarity
messages: Belongs to the GSP E family.

1712410:BR63 RS11450
gene id: 1712410:BR63_RS11450
uniprot id: A0A7G6E458
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1712410:BR63 RS11585
gene id: 1712410:BR63_RS11585
uniprot id: A0A7G6E484
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1712410:BR63 RS16285
gene id: 1712410:BR63_RS16285
uniprot id: A0A7G6E6H7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1712410:BR63 RS06970
gene id: 1712410:BR63_RS06970
uniprot id: A0A7G6E1W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1712410:BR63 RS15195
gene id: 1712410:BR63_RS15195
uniprot id: A0A7G6E5Z8
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS02235
gene id: 1712410:BR63_RS02235
uniprot id: A0A7G6DZI0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1712410:BR63 RS05405
gene id: 1712410:BR63_RS05405
uniprot id: A0A7G6E140
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1712410:BR63 RS10740
gene id: 1712410:BR63_RS10740
uniprot id: A0A7G6E3T0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1712410:BR63 RS14605
gene id: 1712410:BR63_RS14605
uniprot id: A0A7G6E5P9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1712410:BR63 RS02765
gene id: 1712410:BR63_RS02765
uniprot id: A0A7G6DZS1
names: Similarity
messages: Belongs to the EamA transporter family.

1712410:BR63 RS09805
gene id: 1712410:BR63_RS09805
uniprot id: A0A7G6E3B8
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

1712410:BR63 RS04215
gene id: 1712410:BR63_RS04215
uniprot id: A0A7G6E0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1712410:BR63 RS14810
gene id: 1712410:BR63_RS14810
uniprot id: A0A7G6E5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1712410:BR63 RS04005
gene id: 1712410:BR63_RS04005
uniprot id: A0A7G6E0E5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1712410:BR63 RS00150
gene id: 1712410:BR63_RS00150
uniprot id: A0A7G6DYH4
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS05385
gene id: 1712410:BR63_RS05385
uniprot id: A0A7G6E137
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS01485
gene id: 1712410:BR63_RS01485
uniprot id: A0A7G6DZ53
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1712410:BR63 RS12445
gene id: 1712410:BR63_RS12445
uniprot id: A0A7G6E4N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS09900
gene id: 1712410:BR63_RS09900
uniprot id: A0A7G6E3D5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1712410:BR63 RS17605
gene id: 1712410:BR63_RS17605
uniprot id: A0A7G6E752
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS12580
gene id: 1712410:BR63_RS12580
uniprot id: A0A7G6E4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1712410:BR63 RS01175
gene id: 1712410:BR63_RS01175
uniprot id: A0A7G6DZ01
names: Similarity
messages: Belongs to the P(II) protein family.

1712410:BR63 RS05275
gene id: 1712410:BR63_RS05275
uniprot id: A0A7G6E117
names: Subcellular Location Annotation
messages: Cytoplasm

1712410:BR63 RS07445
gene id: 1712410:BR63_RS07445
uniprot id: A0A7G6E254
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1712410:BR63 RS15625
gene id: 1712410:BR63_RS15625
uniprot id: A0A7G6E664
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1712410:BR63 RS04375
gene id: 1712410:BR63_RS04375
uniprot id: A0A7G6E0L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1712410:BR63 RS18865
gene id: 1712410:BR63_RS18865
uniprot id: A0A7G6E7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1712410:BR63 RS05235
gene id: 1712410:BR63_RS05235
uniprot id: A0A7G6E109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1712410:BR63 RS08615
gene id: 1712410:BR63_RS08615
uniprot id: A0A7G6E2R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS16095
gene id: 1712410:BR63_RS16095
uniprot id: A0A7G6E6E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1712410:BR63 RS12220
gene id: 1712410:BR63_RS12220
uniprot id: A0A7G6E4J4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1712410:BR63 RS02610
gene id: 1712410:BR63_RS02610
uniprot id: A0A7G6DZP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS15170
gene id: 1712410:BR63_RS15170
uniprot id: A0A7G6E5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1712410:BR63 RS06415
gene id: 1712410:BR63_RS06415
uniprot id: A0A7G6E1M2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1712410:BR63 RS12140
gene id: 1712410:BR63_RS12140
uniprot id: A0A7G6E4H8
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS02535
gene id: 1712410:BR63_RS02535
uniprot id: A0A7G6DZN0
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1712410:BR63 RS11150
gene id: 1712410:BR63_RS11150
uniprot id: A0A7G6E408
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS14650
gene id: 1712410:BR63_RS14650
uniprot id: A0A7G6E8P7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS04530
gene id: 1712410:BR63_RS04530
uniprot id: A0A7G6E0N2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1712410:BR63 RS18340
gene id: 1712410:BR63_RS18340
uniprot id: A0A7G6E7J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1712410:BR63 RS06545
gene id: 1712410:BR63_RS06545
uniprot id: A0A7G6E1P8
names: Similarity
messages: Belongs to the HypE family.

1712410:BR63 RS18915
gene id: 1712410:BR63_RS18915
uniprot id: A0A7G6E7U4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1712410:BR63 RS14960
gene id: 1712410:BR63_RS14960
uniprot id: A0A7G6E5V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1712410:BR63 RS02010
gene id: 1712410:BR63_RS02010
uniprot id: A0A7G6DZE6
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1712410:BR63 RS18235
gene id: 1712410:BR63_RS18235
uniprot id: A0A7G6E7H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS15935
gene id: 1712410:BR63_RS15935
uniprot id: A0A7G6E6C0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1712410:BR63 RS03030
gene id: 1712410:BR63_RS03030
uniprot id: A0A7G6DZW8
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS10585
gene id: 1712410:BR63_RS10585
uniprot id: A0A7G6E3Q3
names: Similarity
messages: Belongs to the HypE family.

1712410:BR63 RS14400
gene id: 1712410:BR63_RS14400
uniprot id: A0A7G6E5L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1712410:BR63 RS07265
gene id: 1712410:BR63_RS07265
uniprot id: A0A7G6E220
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS07715
gene id: 1712410:BR63_RS07715
uniprot id: A0A7G6E2A2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1712410:BR63 RS14560
gene id: 1712410:BR63_RS14560
uniprot id: A0A7G6E5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1712410:BR63 RS07145
gene id: 1712410:BR63_RS07145
uniprot id: A0A7G6E200
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1712410:BR63 RS02770
gene id: 1712410:BR63_RS02770
uniprot id: A0A7G6DZS2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS15265
gene id: 1712410:BR63_RS15265
uniprot id: A0A7G6E609
names: Similarity
messages: Belongs to the CapA family.

1712410:BR63 RS11710
gene id: 1712410:BR63_RS11710
uniprot id: A0A7G6E4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1712410:BR63 RS04895
gene id: 1712410:BR63_RS04895
uniprot id: A0A7G6E0U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1712410:BR63 RS12770
gene id: 1712410:BR63_RS12770
uniprot id: A0A7G6E4U1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS10980
gene id: 1712410:BR63_RS10980
uniprot id: A0A7G6E3X4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1712410:BR63 RS08395
gene id: 1712410:BR63_RS08395
uniprot id: A0A7G6E2M3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1712410:BR63 RS00165
gene id: 1712410:BR63_RS00165
uniprot id: A0A7G6DYH7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1712410:BR63 RS18755
gene id: 1712410:BR63_RS18755
uniprot id: A0A7G6E7R4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1712410:BR63 RS02395
gene id: 1712410:BR63_RS02395
uniprot id: A0A7G6DZL0
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS18370
gene id: 1712410:BR63_RS18370
uniprot id: A0A7G6E7J7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1712410:BR63 RS12920
gene id: 1712410:BR63_RS12920
uniprot id: A0A7G6E4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

1712410:BR63 RS06005
gene id: 1712410:BR63_RS06005
uniprot id: A0A7G6E1E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1712410:BR63 RS11540
gene id: 1712410:BR63_RS11540
uniprot id: A0A7G6E475
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1712410:BR63 RS04540
gene id: 1712410:BR63_RS04540
uniprot id: A0A7G6E0N4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1712410:BR63 RS11680
gene id: 1712410:BR63_RS11680
uniprot id: A0A7G6E4A2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1712410:BR63 RS08390
gene id: 1712410:BR63_RS08390
uniprot id: A0A7G6E2M2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS16340
gene id: 1712410:BR63_RS16340
uniprot id: A0A7G6E6I7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS17130
gene id: 1712410:BR63_RS17130
uniprot id: A0A7G6E6X1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1712410:BR63 RS07465
gene id: 1712410:BR63_RS07465
uniprot id: A0A7G6E258
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1712410:BR63 RS12215
gene id: 1712410:BR63_RS12215
uniprot id: A0A7G6E4J3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1712410:BR63 RS15710
gene id: 1712410:BR63_RS15710
uniprot id: A0A7G6E679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1712410:BR63 RS09720
gene id: 1712410:BR63_RS09720
uniprot id: A0A7G6E3A3
names: Similarity
messages: Belongs to the UPF0251 family.

1712410:BR63 RS14820
gene id: 1712410:BR63_RS14820
uniprot id: A0A7G6E5S8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1712410:BR63 RS13000
gene id: 1712410:BR63_RS13000
uniprot id: A0A7G6E4X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1712410:BR63 RS07755
gene id: 1712410:BR63_RS07755
uniprot id: A0A7G6E2A8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1712410:BR63 RS05465
gene id: 1712410:BR63_RS05465
uniprot id: A0A7G6E149
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS03910
gene id: 1712410:BR63_RS03910
uniprot id: A0A7G6E0C8
names: Similarity
messages: Belongs to the asp23 family.

1712410:BR63 RS15000
gene id: 1712410:BR63_RS15000
uniprot id: A0A7G6E5W3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1712410:BR63 RS15825
gene id: 1712410:BR63_RS15825
uniprot id: A0A7G6E6A1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1712410:BR63 RS07360
gene id: 1712410:BR63_RS07360
uniprot id: A0A7G6E238
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1712410:BR63 RS13275
gene id: 1712410:BR63_RS13275
uniprot id: A0A7G6E524
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS07255
gene id: 1712410:BR63_RS07255
uniprot id: A0A7G6E218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1712410:BR63 RS00965
gene id: 1712410:BR63_RS00965
uniprot id: A0A7G6DYW2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1712410:BR63 RS12625
gene id: 1712410:BR63_RS12625
uniprot id: A0A7G6E4R6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1712410:BR63 RS13095
gene id: 1712410:BR63_RS13095
uniprot id: A0A7G6E4Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1712410:BR63 RS12630
gene id: 1712410:BR63_RS12630
uniprot id: A0A7G6E4R7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1712410:BR63 RS15575
gene id: 1712410:BR63_RS15575
uniprot id: A0A7G6E655
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1712410:BR63 RS14705
gene id: 1712410:BR63_RS14705
uniprot id: A0A7G6E5R4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1712410:BR63 RS11455
gene id: 1712410:BR63_RS11455
uniprot id: A0A7G6E459
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1712410:BR63 RS10965
gene id: 1712410:BR63_RS10965
uniprot id: A0A7G6E3X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1712410:BR63 RS04725
gene id: 1712410:BR63_RS04725
uniprot id: A0A7G6E0R5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1712410:BR63 RS10700
gene id: 1712410:BR63_RS10700
uniprot id: A0A7G6E3S4
names: Subcellular Location Annotation
messages: Cell membrane

1712410:BR63 RS09920
gene id: 1712410:BR63_RS09920
uniprot id: A0A7G6E3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1712410:BR63 RS17650
gene id: 1712410:BR63_RS17650
uniprot id: A0A7G6E761
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1712410:BR63 RS09455
gene id: 1712410:BR63_RS09455
uniprot id: A0A7G6E359
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1712410:BR63 RS18885
gene id: 1712410:BR63_RS18885
uniprot id: A0A7G6E7T9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1712410:BR63 RS11535
gene id: 1712410:BR63_RS11535
uniprot id: A0A7G6E474
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1712410:BR63 RS15230
gene id: 1712410:BR63_RS15230
uniprot id: A0A7G6E603
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1712410:BR63 RS14260
gene id: 1712410:BR63_RS14260
uniprot id: A0A7G6E5I8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1712410:BR63 RS00400
gene id: 1712410:BR63_RS00400
uniprot id: A0A7G6DYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

1712410:BR63 RS12490
gene id: 1712410:BR63_RS12490
uniprot id: A0A7G6E4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1712410:BR63 RS17305
gene id: 1712410:BR63_RS17305
uniprot id: A0A7G6E6Z9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1712410:BR63 RS09725
gene id: 1712410:BR63_RS09725
uniprot id: A0A7G6E3A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1712410:BR63 RS10015
gene id: 1712410:BR63_RS10015
uniprot id: A0A7G6E3F5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1712410:BR63 RS05230
gene id: 1712410:BR63_RS05230
uniprot id: A0A7G6E108
names: Similarity
messages: Belongs to the MotB family.

1712410:BR63 RS17360
gene id: 1712410:BR63_RS17360
uniprot id: A0A7G6E708
names: Similarity
messages: Belongs to the universal stress protein A family.

1712410:BR63 RS10915
gene id: 1712410:BR63_RS10915
uniprot id: A0A7G6E3W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1712410:BR63 RS09780
gene id: 1712410:BR63_RS09780
uniprot id: A0A7G6E3B3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1712410:BR63 RS12670
gene id: 1712410:BR63_RS12670
uniprot id: A0A7G6E4S3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS05515
gene id: 1712410:BR63_RS05515
uniprot id: A0A7G6E158
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS16385
gene id: 1712410:BR63_RS16385
uniprot id: A0A7G6E6J5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1712410:BR63 RS13040
gene id: 1712410:BR63_RS13040
uniprot id: A0A7G6E4Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1712410:BR63 RS06500
gene id: 1712410:BR63_RS06500
uniprot id: A0A7G6E1N9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1712410:BR63 RS14950
gene id: 1712410:BR63_RS14950
uniprot id: A0A7G6E5V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1712410:BR63 RS08650
gene id: 1712410:BR63_RS08650
uniprot id: A0A7G6E2S0
names: Similarity
messages: Belongs to the UPF0261 family.

1712410:BR63 RS09585
gene id: 1712410:BR63_RS09585
uniprot id: A0A7G6E382
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS12460
gene id: 1712410:BR63_RS12460
uniprot id: A0A7G6E4N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1712410:BR63 RS06695
gene id: 1712410:BR63_RS06695
uniprot id: A0A7G6E1S5
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS15490
gene id: 1712410:BR63_RS15490
uniprot id: A0A7G6E645
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1712410:BR63 RS12365
gene id: 1712410:BR63_RS12365
uniprot id: A0A7G6E4L9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1712410:BR63 RS07180
gene id: 1712410:BR63_RS07180
uniprot id: A0A7G6E205
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1712410:BR63 RS08060
gene id: 1712410:BR63_RS08060
uniprot id: A0A7G6E2G4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS19140
gene id: 1712410:BR63_RS19140
uniprot id: A0A7G6E7Y6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1712410:BR63 RS04660
gene id: 1712410:BR63_RS04660
uniprot id: A0A7G6E0Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS17000
gene id: 1712410:BR63_RS17000
uniprot id: A0A7G6E6V1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1712410:BR63 RS16005
gene id: 1712410:BR63_RS16005
uniprot id: A0A7G6E6D4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS17785
gene id: 1712410:BR63_RS17785
uniprot id: A0A7G6E786
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1712410:BR63 RS15150
gene id: 1712410:BR63_RS15150
uniprot id: A0A7G6E5Y9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1712410:BR63 RS14110
gene id: 1712410:BR63_RS14110
uniprot id: A0A7G6E5G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1712410:BR63 RS15130
gene id: 1712410:BR63_RS15130
uniprot id: A0A7G6E5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1712410:BR63 RS10175
gene id: 1712410:BR63_RS10175
uniprot id: A0A7G6E3H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1712410:BR63 RS04985
gene id: 1712410:BR63_RS04985
uniprot id: A0A7G6E0W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1712410:BR63 RS00625
gene id: 1712410:BR63_RS00625
uniprot id: A0A7G6DYQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS04755
gene id: 1712410:BR63_RS04755
uniprot id: A0A7G6E0S0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1712410:BR63 RS17475
gene id: 1712410:BR63_RS17475
uniprot id: A0A7G6E730
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS05110
gene id: 1712410:BR63_RS05110
uniprot id: A0A7G6E0Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1712410:BR63 RS14880
gene id: 1712410:BR63_RS14880
uniprot id: A0A7G6E8Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1712410:BR63 RS14285
gene id: 1712410:BR63_RS14285
uniprot id: A0A7G6E5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1712410:BR63 RS05020
gene id: 1712410:BR63_RS05020
uniprot id: A0A7G6E0X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1712410:BR63 RS09085
gene id: 1712410:BR63_RS09085
uniprot id: A0A7G6E2Z5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1712410:BR63 RS11045
gene id: 1712410:BR63_RS11045
uniprot id: A0A7G6E3Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS14595
gene id: 1712410:BR63_RS14595
uniprot id: A0A7G6E5P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1712410:BR63 RS00530
gene id: 1712410:BR63_RS00530
uniprot id: A0A7G6E826
names: Similarity
messages: Belongs to the UxaA family.

1712410:BR63 RS05195
gene id: 1712410:BR63_RS05195
uniprot id: A0A7G6E101
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1712410:BR63 RS10800
gene id: 1712410:BR63_RS10800
uniprot id: A0A7G6E3U2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1712410:BR63 RS17700
gene id: 1712410:BR63_RS17700
uniprot id: A0A7G6E770
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1712410:BR63 RS10760
gene id: 1712410:BR63_RS10760
uniprot id: A0A7G6E3T4
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

1712410:BR63 RS09560
gene id: 1712410:BR63_RS09560
uniprot id: A0A7G6E377
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1712410:BR63 RS00270
gene id: 1712410:BR63_RS00270
uniprot id: A0A7G6DYJ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS09925
gene id: 1712410:BR63_RS09925
uniprot id: A0A7G6E3D8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1712410:BR63 RS16990
gene id: 1712410:BR63_RS16990
uniprot id: A0A7G6E6V0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1712410:BR63 RS09445
gene id: 1712410:BR63_RS09445
uniprot id: A0A7G6E358
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS01580
gene id: 1712410:BR63_RS01580
uniprot id: A0A7G6DZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS02270
gene id: 1712410:BR63_RS02270
uniprot id: A0A7G6DZI6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1712410:BR63 RS17495
gene id: 1712410:BR63_RS17495
uniprot id: A0A7G6E734
names: Similarity
messages: Belongs to the class-I fumarase family.

1712410:BR63 RS06520
gene id: 1712410:BR63_RS06520
uniprot id: A0A7G6E1P3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS14580
gene id: 1712410:BR63_RS14580
uniprot id: A0A7G6E5P4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1712410:BR63 RS14050
gene id: 1712410:BR63_RS14050
uniprot id: A0A7G6E5F1
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS03415
gene id: 1712410:BR63_RS03415
uniprot id: A0A7G6E042
names: Similarity
messages: Belongs to the UPF0751 family.

1712410:BR63 RS02340
gene id: 1712410:BR63_RS02340
uniprot id: A0A7G6DZJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS17835
gene id: 1712410:BR63_RS17835
uniprot id: A0A7G6E795
names: Similarity
messages: Belongs to the AOR/FOR family.

1712410:BR63 RS08255
gene id: 1712410:BR63_RS08255
uniprot id: A0A7G6E2J6
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS05290
gene id: 1712410:BR63_RS05290
uniprot id: A0A7G6E120
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1712410:BR63 RS05935
gene id: 1712410:BR63_RS05935
uniprot id: A0A7G6E1D5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1712410:BR63 RS14920
gene id: 1712410:BR63_RS14920
uniprot id: A0A7G6E5U7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1712410:BR63 RS11820
gene id: 1712410:BR63_RS11820
uniprot id: A0A7G6E4C5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS14085
gene id: 1712410:BR63_RS14085
uniprot id: A0A7G6E5F8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1712410:BR63 RS18110
gene id: 1712410:BR63_RS18110
uniprot id: A0A7G6E7E6
names: Subcellular Location Annotation
messages: Bacterial microcompartment

1712410:BR63 RS00895
gene id: 1712410:BR63_RS00895
uniprot id: A0A7G6DYU9
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS12515
gene id: 1712410:BR63_RS12515
uniprot id: A0A7G6E4P8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1712410:BR63 RS08565
gene id: 1712410:BR63_RS08565
uniprot id: A0A7G6E2Q4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1712410:BR63 RS11930
gene id: 1712410:BR63_RS11930
uniprot id: A0A7G6E4E7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1712410:BR63 RS12840
gene id: 1712410:BR63_RS12840
uniprot id: A0A7G6E4V5
names: Similarity
messages: Belongs to the archaeal-type GPI family.

1712410:BR63 RS05945
gene id: 1712410:BR63_RS05945
uniprot id: A0A7G6E1D7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1712410:BR63 RS09180
gene id: 1712410:BR63_RS09180
uniprot id: A0A7G6E312
names: Similarity
messages: Belongs to the AOR/FOR family.

1712410:BR63 RS00645
gene id: 1712410:BR63_RS00645
uniprot id: A0A7G6DYQ7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS08435
gene id: 1712410:BR63_RS08435
uniprot id: A0A7G6E2N1
names: Similarity
messages: Belongs to the AOR/FOR family.

1712410:BR63 RS07985
gene id: 1712410:BR63_RS07985
uniprot id: A0A7G6E2E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1712410:BR63 RS01350
gene id: 1712410:BR63_RS01350
uniprot id: A0A7G6DZ30
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1712410:BR63 RS16875
gene id: 1712410:BR63_RS16875
uniprot id: A0A7G6E6T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1712410:BR63 RS15455
gene id: 1712410:BR63_RS15455
uniprot id: A0A7G6E641
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1712410:BR63 RS17315
gene id: 1712410:BR63_RS17315
uniprot id: A0A7G6E701
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1712410:BR63 RS07225
gene id: 1712410:BR63_RS07225
uniprot id: A0A7G6E212
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1712410:BR63 RS07470
gene id: 1712410:BR63_RS07470
uniprot id: A0A7G6E259
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1712410:BR63 RS01180
gene id: 1712410:BR63_RS01180
uniprot id: A0A7G6DZ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS12730
gene id: 1712410:BR63_RS12730
uniprot id: A0A7G6E4T4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1712410:BR63 RS10960
gene id: 1712410:BR63_RS10960
uniprot id: A0A7G6E3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1712410:BR63 RS00975
gene id: 1712410:BR63_RS00975
uniprot id: A0A7G6DYW4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1712410:BR63 RS13335
gene id: 1712410:BR63_RS13335
uniprot id: A0A7G6E535
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1712410:BR63 RS06975
gene id: 1712410:BR63_RS06975
uniprot id: A0A7G6E1W9
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

1712410:BR63 RS14500
gene id: 1712410:BR63_RS14500
uniprot id: A0A7G6E5N0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1712410:BR63 RS14245
gene id: 1712410:BR63_RS14245
uniprot id: A0A7G6E5I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1712410:BR63 RS02390
gene id: 1712410:BR63_RS02390
uniprot id: A0A7G6DZK9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1712410:BR63 RS07270
gene id: 1712410:BR63_RS07270
uniprot id: A0A7G6E221
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1712410:BR63 RS07450
gene id: 1712410:BR63_RS07450
uniprot id: A0A7G6E255
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1712410:BR63 RS10265
gene id: 1712410:BR63_RS10265
uniprot id: A0A7G6E3J7
names: Similarity
messages: Belongs to the peptidase A31 family.

1712410:BR63 RS18570
gene id: 1712410:BR63_RS18570
uniprot id: A0A7G6E7N2
names: Similarity
messages: Belongs to the UPF0045 family.

1712410:BR63 RS17300
gene id: 1712410:BR63_RS17300
uniprot id: A0A7G6E6Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1712410:BR63 RS14965
gene id: 1712410:BR63_RS14965
uniprot id: A0A7G6E5V6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1712410:BR63 RS11180
gene id: 1712410:BR63_RS11180
uniprot id: A0A7G6E413
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS16280
gene id: 1712410:BR63_RS16280
uniprot id: A0A7G6E6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1712410:BR63 RS05555
gene id: 1712410:BR63_RS05555
uniprot id: A0A7G6E166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS03080
gene id: 1712410:BR63_RS03080
uniprot id: A0A7G6DZX7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1712410:BR63 RS08400
gene id: 1712410:BR63_RS08400
uniprot id: A0A7G6E2M4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS00130
gene id: 1712410:BR63_RS00130
uniprot id: A0A7G6DYH0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1712410:BR63 RS01470
gene id: 1712410:BR63_RS01470
uniprot id: A0A7G6DZ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

1712410:BR63 RS08875
gene id: 1712410:BR63_RS08875
uniprot id: A0A7G6E2V7
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS14955
gene id: 1712410:BR63_RS14955
uniprot id: A0A7G6E5V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1712410:BR63 RS08270
gene id: 1712410:BR63_RS08270
uniprot id: A0A7G6E2J9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1712410:BR63 RS10180
gene id: 1712410:BR63_RS10180
uniprot id: A0A7G6E3I0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1712410:BR63 RS10170
gene id: 1712410:BR63_RS10170
uniprot id: A0A7G6E3H8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1712410:BR63 RS05335
gene id: 1712410:BR63_RS05335
uniprot id: A0A7G6E128
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1712410:BR63 RS12410
gene id: 1712410:BR63_RS12410
uniprot id: A0A7G6E4M8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1712410:BR63 RS13955
gene id: 1712410:BR63_RS13955
uniprot id: A0A7G6E5D5
names: Similarity
messages: Belongs to the UPF0045 family.

1712410:BR63 RS10660
gene id: 1712410:BR63_RS10660
uniprot id: A0A7G6E3R7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1712410:BR63 RS16490
gene id: 1712410:BR63_RS16490
uniprot id: A0A7G6E6L4
names: Similarity
messages: Belongs to the peptidase A24 family.

1712410:BR63 RS17775
gene id: 1712410:BR63_RS17775
uniprot id: A0A7G6E784
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1712410:BR63 RS01245
gene id: 1712410:BR63_RS01245
uniprot id: A0A7G6DZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1712410:BR63 RS08700
gene id: 1712410:BR63_RS08700
uniprot id: A0A7G6E2T0
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS14040
gene id: 1712410:BR63_RS14040
uniprot id: A0A7G6E5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1712410:BR63 RS01225
gene id: 1712410:BR63_RS01225
uniprot id: A0A7G6DZ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1712410:BR63 RS08405
gene id: 1712410:BR63_RS08405
uniprot id: A0A7G6E2M5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1712410:BR63 RS18575
gene id: 1712410:BR63_RS18575
uniprot id: A0A7G6E7N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS13760
gene id: 1712410:BR63_RS13760
uniprot id: A0A7G6E5A2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1712410:BR63 RS13980
gene id: 1712410:BR63_RS13980
uniprot id: A0A7G6E5D9
names: Similarity
messages: Belongs to the peptidase S8 family.

1712410:BR63 RS14860
gene id: 1712410:BR63_RS14860
uniprot id: A0A7G6E5T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1712410:BR63 RS13210
gene id: 1712410:BR63_RS13210
uniprot id: A0A7G6E513
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1712410:BR63 RS06285
gene id: 1712410:BR63_RS06285
uniprot id: A0A7G6E1J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1712410:BR63 RS08240
gene id: 1712410:BR63_RS08240
uniprot id: A0A7G6E8E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1712410:BR63 RS04865
gene id: 1712410:BR63_RS04865
uniprot id: A0A7G6E0U1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1712410:BR63 RS01790
gene id: 1712410:BR63_RS01790
uniprot id: A0A7G6DZA7
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS02730
gene id: 1712410:BR63_RS02730
uniprot id: A0A7G6DZR4
names: Similarity
messages: Belongs to the UPF0473 family.

1712410:BR63 RS12230
gene id: 1712410:BR63_RS12230
uniprot id: A0A7G6E4J6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1712410:BR63 RS11700
gene id: 1712410:BR63_RS11700
uniprot id: A0A7G6E4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1712410:BR63 RS05210
gene id: 1712410:BR63_RS05210
uniprot id: A0A7G6E104
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS11920
gene id: 1712410:BR63_RS11920
uniprot id: A0A7G6E4E5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1712410:BR63 RS02525
gene id: 1712410:BR63_RS02525
uniprot id: A0A7G6DZM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1712410:BR63 RS16985
gene id: 1712410:BR63_RS16985
uniprot id: A0A7G6E6U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1712410:BR63 RS16360
gene id: 1712410:BR63_RS16360
uniprot id: A0A7G6E6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1712410:BR63 RS02625
gene id: 1712410:BR63_RS02625
uniprot id: A0A7G6DZP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS06145
gene id: 1712410:BR63_RS06145
uniprot id: A0A7G6E1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1712410:BR63 RS13635
gene id: 1712410:BR63_RS13635
uniprot id: A0A7G6E583
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1712410:BR63 RS18500
gene id: 1712410:BR63_RS18500
uniprot id: A0A7G6E7M0
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS01465
gene id: 1712410:BR63_RS01465
uniprot id: A0A7G6DZ50
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS18330
gene id: 1712410:BR63_RS18330
uniprot id: A0A7G6E7I9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS08715
gene id: 1712410:BR63_RS08715
uniprot id: A0A7G6E2T3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1712410:BR63 RS09795
gene id: 1712410:BR63_RS09795
uniprot id: A0A7G6E3B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1712410:BR63 RS07370
gene id: 1712410:BR63_RS07370
uniprot id: A0A7G6E240
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1712410:BR63 RS14750
gene id: 1712410:BR63_RS14750
uniprot id: A0A7G6E8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1712410:BR63 RS09040
gene id: 1712410:BR63_RS09040
uniprot id: A0A7G6E2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1712410:BR63 RS05380
gene id: 1712410:BR63_RS05380
uniprot id: A0A7G6E136
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1712410:BR63 RS16320
gene id: 1712410:BR63_RS16320
uniprot id: A0A7G6E6I3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS18070
gene id: 1712410:BR63_RS18070
uniprot id: A0A7G6E7D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS09305
gene id: 1712410:BR63_RS09305
uniprot id: A0A7G6E333
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1712410:BR63 RS09450
gene id: 1712410:BR63_RS09450
uniprot id: A0A7G6E8G5
names: Similarity
messages: Belongs to the GARS family.

1712410:BR63 RS02250
gene id: 1712410:BR63_RS02250
uniprot id: A0A7G6DZI2
names: Similarity
messages: Belongs to the asp23 family.

1712410:BR63 RS12285
gene id: 1712410:BR63_RS12285
uniprot id: A0A7G6E4K6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS17410
gene id: 1712410:BR63_RS17410
uniprot id: A0A7G6E717
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1712410:BR63 RS11485
gene id: 1712410:BR63_RS11485
uniprot id: A0A7G6E464
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1712410:BR63 RS07480
gene id: 1712410:BR63_RS07480
uniprot id: A0A7G6E261
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1712410:BR63 RS12145
gene id: 1712410:BR63_RS12145
uniprot id: A0A7G6E4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1712410:BR63 RS02275
gene id: 1712410:BR63_RS02275
uniprot id: A0A7G6DZI7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1712410:BR63 RS09240
gene id: 1712410:BR63_RS09240
uniprot id: A0A7G6E323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1712410:BR63 RS09050
gene id: 1712410:BR63_RS09050
uniprot id: A0A7G6E2Y9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1712410:BR63 RS00805
gene id: 1712410:BR63_RS00805
uniprot id: A0A7G6DYT6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1712410:BR63 RS00105
gene id: 1712410:BR63_RS00105
uniprot id: A0A7G6DYG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1712410:BR63 RS16645
gene id: 1712410:BR63_RS16645
uniprot id: A0A7G6E6P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1712410:BR63 RS08285
gene id: 1712410:BR63_RS08285
uniprot id: A0A7G6E2K2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS09060
gene id: 1712410:BR63_RS09060
uniprot id: A0A7G6E2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS11545
gene id: 1712410:BR63_RS11545
uniprot id: A0A7G6E476
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1712410:BR63 RS02670
gene id: 1712410:BR63_RS02670
uniprot id: A0A7G6DZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1712410:BR63 RS06635
gene id: 1712410:BR63_RS06635
uniprot id: A0A7G6E1R3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1712410:BR63 RS14915
gene id: 1712410:BR63_RS14915
uniprot id: A0A7G6E5U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1712410:BR63 RS18830
gene id: 1712410:BR63_RS18830
uniprot id: A0A7G6E7S8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1712410:BR63 RS09465
gene id: 1712410:BR63_RS09465
uniprot id: A0A7G6E361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1712410:BR63 RS14225
gene id: 1712410:BR63_RS14225
uniprot id: A0A7G6E5I2
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS06745
gene id: 1712410:BR63_RS06745
uniprot id: A0A7G6E1T4
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS11435
gene id: 1712410:BR63_RS11435
uniprot id: A0A7G6E455
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1712410:BR63 RS12525
gene id: 1712410:BR63_RS12525
uniprot id: A0A7G6E4Q0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1712410:BR63 RS14740
gene id: 1712410:BR63_RS14740
uniprot id: A0A7G6E5R9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1712410:BR63 RS10750
gene id: 1712410:BR63_RS10750
uniprot id: A0A7G6E3T2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1712410:BR63 RS09265
gene id: 1712410:BR63_RS09265
uniprot id: A0A7G6E327
names: Similarity
messages: Belongs to the carbamate kinase family.

1712410:BR63 RS09415
gene id: 1712410:BR63_RS09415
uniprot id: A0A7G6E352
names: Similarity
messages: Belongs to the GerABKA family.

1712410:BR63 RS13995
gene id: 1712410:BR63_RS13995
uniprot id: A0A7G6E8N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1712410:BR63 RS14410
gene id: 1712410:BR63_RS14410
uniprot id: A0A7G6E5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1712410:BR63 RS12535
gene id: 1712410:BR63_RS12535
uniprot id: A0A7G6E4Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS17610
gene id: 1712410:BR63_RS17610
uniprot id: A0A7G6E753
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1712410:BR63 RS09570
gene id: 1712410:BR63_RS09570
uniprot id: A0A7G6E379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1712410:BR63 RS10510
gene id: 1712410:BR63_RS10510
uniprot id: A0A7G6E3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1712410:BR63 RS14825
gene id: 1712410:BR63_RS14825
uniprot id: A0A7G6E5S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1712410:BR63 RS13605
gene id: 1712410:BR63_RS13605
uniprot id: A0A7G6E581
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1712410:BR63 RS08900
gene id: 1712410:BR63_RS08900
uniprot id: A0A7G6E2W2
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS11425
gene id: 1712410:BR63_RS11425
uniprot id: A0A7G6E8K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1712410:BR63 RS10690
gene id: 1712410:BR63_RS10690
uniprot id: A0A7G6E3S2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS11890
gene id: 1712410:BR63_RS11890
uniprot id: A0A7G6E4D9
names: Similarity
messages: Belongs to the AOR/FOR family.

1712410:BR63 RS00820
gene id: 1712410:BR63_RS00820
uniprot id: A0A7G6DYT9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1712410:BR63 RS10995
gene id: 1712410:BR63_RS10995
uniprot id: A0A7G6E3X7
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1712410:BR63 RS09490
gene id: 1712410:BR63_RS09490
uniprot id: A0A7G6E8G6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1712410:BR63 RS14080
gene id: 1712410:BR63_RS14080
uniprot id: A0A7G6E5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1712410:BR63 RS05330
gene id: 1712410:BR63_RS05330
uniprot id: A0A7G6E127
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1712410:BR63 RS01500
gene id: 1712410:BR63_RS01500
uniprot id: A0A7G6DZ55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1712410:BR63 RS07540
gene id: 1712410:BR63_RS07540
uniprot id: A0A7G6E272
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1712410:BR63 RS02655
gene id: 1712410:BR63_RS02655
uniprot id: A0A7G6DZQ0
names: Similarity
messages: Belongs to the threonine aldolase family.

1712410:BR63 RS17865
gene id: 1712410:BR63_RS17865
uniprot id: A0A7G6E7A1
names: Similarity
messages: Belongs to the UPF0178 family.

1712410:BR63 RS10725
gene id: 1712410:BR63_RS10725
uniprot id: A0A7G6E8J0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1712410:BR63 RS04640
gene id: 1712410:BR63_RS04640
uniprot id: A0A7G6E0P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1712410:BR63 RS09935
gene id: 1712410:BR63_RS09935
uniprot id: A0A7G6E8H8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1712410:BR63 RS03045
gene id: 1712410:BR63_RS03045
uniprot id: A0A7G6DZX0
names: Similarity
messages: Belongs to the GSP E family.

1712410:BR63 RS07240
gene id: 1712410:BR63_RS07240
uniprot id: A0A7G6E215
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1712410:BR63 RS10985
gene id: 1712410:BR63_RS10985
uniprot id: A0A7G6E3X5
names: Similarity
messages: Belongs to the peptidase A31 family.

1712410:BR63 RS18465
gene id: 1712410:BR63_RS18465
uniprot id: A0A7G6E7L3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1712410:BR63 RS12105
gene id: 1712410:BR63_RS12105
uniprot id: A0A7G6E4H1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1712410:BR63 RS15375
gene id: 1712410:BR63_RS15375
uniprot id: A0A7G6E626
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1712410:BR63 RS15865
gene id: 1712410:BR63_RS15865
uniprot id: A0A7G6E6A9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1712410:BR63 RS12960
gene id: 1712410:BR63_RS12960
uniprot id: A0A7G6E4X7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1712410:BR63 RS16310
gene id: 1712410:BR63_RS16310
uniprot id: A0A7G6E6I2
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1712410:BR63 RS16380
gene id: 1712410:BR63_RS16380
uniprot id: A0A7G6E6J4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1712410:BR63 RS13240
gene id: 1712410:BR63_RS13240
uniprot id: A0A7G6E519
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS01150
gene id: 1712410:BR63_RS01150
uniprot id: A0A7G6DYZ6
names: Similarity
messages: Belongs to the glutamate synthase family.

1712410:BR63 RS09375
gene id: 1712410:BR63_RS09375
uniprot id: A0A7G6E345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1712410:BR63 RS18975
gene id: 1712410:BR63_RS18975
uniprot id: A0A7G6E7V5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1712410:BR63 RS09410
gene id: 1712410:BR63_RS09410
uniprot id: A0A7G6E351
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1712410:BR63 RS07925
gene id: 1712410:BR63_RS07925
uniprot id: A0A7G6E2D8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1712410:BR63 RS12655
gene id: 1712410:BR63_RS12655
uniprot id: A0A7G6E4S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1712410:BR63 RS00085
gene id: 1712410:BR63_RS00085
uniprot id: A0A7G6DYG3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1712410:BR63 RS11615
gene id: 1712410:BR63_RS11615
uniprot id: A0A7G6E490
names: Subcellular Location Annotation
messages: Cytoplasm

1712410:BR63 RS05300
gene id: 1712410:BR63_RS05300
uniprot id: A0A7G6E122
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1712410:BR63 RS00535
gene id: 1712410:BR63_RS00535
uniprot id: A0A7G6DYN7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1712410:BR63 RS18210
gene id: 1712410:BR63_RS18210
uniprot id: A0A7G6E7G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS16820
gene id: 1712410:BR63_RS16820
uniprot id: A0A7G6E6S5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1712410:BR63 RS08475
gene id: 1712410:BR63_RS08475
uniprot id: A0A7G6E2N8
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1712410:BR63 RS08345
gene id: 1712410:BR63_RS08345
uniprot id: A0A7G6E2L3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1712410:BR63 RS15620
gene id: 1712410:BR63_RS15620
uniprot id: A0A7G6E663
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1712410:BR63 RS10860
gene id: 1712410:BR63_RS10860
uniprot id: A0A7G6E3V2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1712410:BR63 RS18410
gene id: 1712410:BR63_RS18410
uniprot id: A0A7G6E7K4
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS05930
gene id: 1712410:BR63_RS05930
uniprot id: A0A7G6E1D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1712410:BR63 RS03310
gene id: 1712410:BR63_RS03310
uniprot id: A0A7G6E022
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1712410:BR63 RS01785
gene id: 1712410:BR63_RS01785
uniprot id: A0A7G6DZA6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1712410:BR63 RS09510
gene id: 1712410:BR63_RS09510
uniprot id: A0A7G6E368
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS09940
gene id: 1712410:BR63_RS09940
uniprot id: A0A7G6E3E0
names: Similarity
messages: Belongs to the UPF0749 family.

1712410:BR63 RS11460
gene id: 1712410:BR63_RS11460
uniprot id: A0A7G6E460
names: Similarity
messages: Belongs to the sigma-54 factor family.

1712410:BR63 RS12755
gene id: 1712410:BR63_RS12755
uniprot id: A0A7G6E4T8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1712410:BR63 RS16350
gene id: 1712410:BR63_RS16350
uniprot id: A0A7G6E6I9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS11550
gene id: 1712410:BR63_RS11550
uniprot id: A0A7G6E477
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1712410:BR63 RS06260
gene id: 1712410:BR63_RS06260
uniprot id: A0A7G6E1J2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1712410:BR63 RS18765
gene id: 1712410:BR63_RS18765
uniprot id: A0A7G6E7R6
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS00955
gene id: 1712410:BR63_RS00955
uniprot id: A0A7G6DYW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1712410:BR63 RS04780
gene id: 1712410:BR63_RS04780
uniprot id: A0A7G6E0S5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1712410:BR63 RS18660
gene id: 1712410:BR63_RS18660
uniprot id: A0A7G6E7P9
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS03945
gene id: 1712410:BR63_RS03945
uniprot id: A0A7G6E0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1712410:BR63 RS18645
gene id: 1712410:BR63_RS18645
uniprot id: A0A7G6E7P6
names: Similarity
messages: Belongs to the NadC/ModD family.

1712410:BR63 RS16090
gene id: 1712410:BR63_RS16090
uniprot id: A0A7G6E6E8
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1712410:BR63 RS01095
gene id: 1712410:BR63_RS01095
uniprot id: A0A7G6DYY5
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS14930
gene id: 1712410:BR63_RS14930
uniprot id: A0A7G6E5U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1712410:BR63 RS12810
gene id: 1712410:BR63_RS12810
uniprot id: A0A7G6E4U9
names: Similarity
messages: Belongs to the CpsD/CapB family.

1712410:BR63 RS10840
gene id: 1712410:BR63_RS10840
uniprot id: A0A7G6E3U9
names: Similarity
messages: Belongs to the CFA/CMAS family.

1712410:BR63 RS06530
gene id: 1712410:BR63_RS06530
uniprot id: A0A7G6E1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1712410:BR63 RS05255
gene id: 1712410:BR63_RS05255
uniprot id: A0A7G6E113
names: Similarity
messages: Belongs to the FlgD family.

1712410:BR63 RS06090
gene id: 1712410:BR63_RS06090
uniprot id: A0A7G6E1G2
names: Similarity
messages: Belongs to the UPF0102 family.

1712410:BR63 RS04260
gene id: 1712410:BR63_RS04260
uniprot id: A0A7G6E0J1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1712410:BR63 RS12545
gene id: 1712410:BR63_RS12545
uniprot id: A0A7G6E4Q3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1712410:BR63 RS03145
gene id: 1712410:BR63_RS03145
uniprot id: A0A7G6DZZ0
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS14450
gene id: 1712410:BR63_RS14450
uniprot id: A0A7G6E5M0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1712410:BR63 RS02660
gene id: 1712410:BR63_RS02660
uniprot id: A0A7G6DZQ1
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1712410:BR63 RS18785
gene id: 1712410:BR63_RS18785
uniprot id: A0A7G6E7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1712410:BR63 RS16065
gene id: 1712410:BR63_RS16065
uniprot id: A0A7G6E6E3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1712410:BR63 RS01725
gene id: 1712410:BR63_RS01725
uniprot id: A0A7G6DZ96
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS12585
gene id: 1712410:BR63_RS12585
uniprot id: A0A7G6E4R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1712410:BR63 RS14755
gene id: 1712410:BR63_RS14755
uniprot id: A0A7G6E5S0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS09755
gene id: 1712410:BR63_RS09755
uniprot id: A0A7G6E3A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1712410:BR63 RS11175
gene id: 1712410:BR63_RS11175
uniprot id: A0A7G6E412
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1712410:BR63 RS06200
gene id: 1712410:BR63_RS06200
uniprot id: A0A7G6E1I2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1712410:BR63 RS13510
gene id: 1712410:BR63_RS13510
uniprot id: A0A7G6E564
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1712410:BR63 RS03315
gene id: 1712410:BR63_RS03315
uniprot id: A0A7G6E023
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1712410:BR63 RS06450
gene id: 1712410:BR63_RS06450
uniprot id: A0A7G6E1M9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1712410:BR63 RS05560
gene id: 1712410:BR63_RS05560
uniprot id: A0A7G6E167
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS07485
gene id: 1712410:BR63_RS07485
uniprot id: A0A7G6E262
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1712410:BR63 RS17355
gene id: 1712410:BR63_RS17355
uniprot id: A0A7G6E707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1712410:BR63 RS16190
gene id: 1712410:BR63_RS16190
uniprot id: A0A7G6E6G0
names: Similarity
messages: Belongs to the glutamate synthase family.

1712410:BR63 RS08885
gene id: 1712410:BR63_RS08885
uniprot id: A0A7G6E2V9
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS04935
gene id: 1712410:BR63_RS04935
uniprot id: A0A7G6E0V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1712410:BR63 RS12530
gene id: 1712410:BR63_RS12530
uniprot id: A0A7G6E4Q1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1712410:BR63 RS07680
gene id: 1712410:BR63_RS07680
uniprot id: A0A7G6E297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS19005
gene id: 1712410:BR63_RS19005
uniprot id: A0A7G6E7W1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS10190
gene id: 1712410:BR63_RS10190
uniprot id: A0A7G6E3I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1712410:BR63 RS06535
gene id: 1712410:BR63_RS06535
uniprot id: A0A7G6E1P6
names: Similarity
messages: Belongs to the RemA family.

1712410:BR63 RS05745
gene id: 1712410:BR63_RS05745
uniprot id: A0A7G6E1A3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1712410:BR63 RS00730
gene id: 1712410:BR63_RS00730
uniprot id: A0A7G6E829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS11440
gene id: 1712410:BR63_RS11440
uniprot id: A0A7G6E456
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1712410:BR63 RS05320
gene id: 1712410:BR63_RS05320
uniprot id: A0A7G6E126
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1712410:BR63 RS08075
gene id: 1712410:BR63_RS08075
uniprot id: A0A7G6E2G7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS05440
gene id: 1712410:BR63_RS05440
uniprot id: A0A7G6E146
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1712410:BR63 RS11775
gene id: 1712410:BR63_RS11775
uniprot id: A0A7G6E4B7
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS16150
gene id: 1712410:BR63_RS16150
uniprot id: A0A7G6E6F6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1712410:BR63 RS16020
gene id: 1712410:BR63_RS16020
uniprot id: A0A7G6E6D5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712410:BR63 RS02545
gene id: 1712410:BR63_RS02545
uniprot id: A0A7G6DZN2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1712410:BR63 RS10950
gene id: 1712410:BR63_RS10950
uniprot id: A0A7G6E3W8
names: Similarity
messages: Belongs to the HupF/HypC family.

1712410:BR63 RS15855
gene id: 1712410:BR63_RS15855
uniprot id: A0A7G6E6A7
names: Similarity
messages: Belongs to the MecA family.

1712410:BR63 RS12480
gene id: 1712410:BR63_RS12480
uniprot id: A0A7G6E4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1712410:BR63 RS18180
gene id: 1712410:BR63_RS18180
uniprot id: A0A7G6E7G0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1712410:BR63 RS00610
gene id: 1712410:BR63_RS00610
uniprot id: A0A7G6DYQ1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1712410:BR63 RS10305
gene id: 1712410:BR63_RS10305
uniprot id: A0A7G6E3K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

1712410:BR63 RS04880
gene id: 1712410:BR63_RS04880
uniprot id: A0A7G6E0U4
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

1712410:BR63 RS03925
gene id: 1712410:BR63_RS03925
uniprot id: A0A7G6E0D1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1712410:BR63 RS15920
gene id: 1712410:BR63_RS15920
uniprot id: A0A7G6E6B7
names: Similarity
messages: Belongs to the PrpD family.

1712410:BR63 RS03950
gene id: 1712410:BR63_RS03950
uniprot id: A0A7G6E0D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1712410:BR63 RS06280
gene id: 1712410:BR63_RS06280
uniprot id: A0A7G6E1J6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1712410:BR63 RS12910
gene id: 1712410:BR63_RS12910
uniprot id: A0A7G6E4W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1712410:BR63 RS02195
gene id: 1712410:BR63_RS02195
uniprot id: A0A7G6DZH5
names: Similarity
messages: Belongs to the UPF0342 family.

1712410:BR63 RS06505
gene id: 1712410:BR63_RS06505
uniprot id: A0A7G6E1P0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1712410:BR63 RS17930
gene id: 1712410:BR63_RS17930
uniprot id: A0A7G6E7B3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1712410:BR63 RS00490
gene id: 1712410:BR63_RS00490
uniprot id: A0A7G6DYN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1712410:BR63 RS12185
gene id: 1712410:BR63_RS12185
uniprot id: A0A7G6E4I7
names: Similarity
messages: Belongs to the SecB family.

1712410:BR63 RS14865
gene id: 1712410:BR63_RS14865
uniprot id: A0A7G6E5T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1712410:BR63 RS12495
gene id: 1712410:BR63_RS12495
uniprot id: A0A7G6E8L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1712410:BR63 RS13550
gene id: 1712410:BR63_RS13550
uniprot id: A0A7G6E571
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1712410:BR63 RS04720
gene id: 1712410:BR63_RS04720
uniprot id: A0A7G6E0R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1712410:BR63 RS01930
gene id: 1712410:BR63_RS01930
uniprot id: A0A7G6E849
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1712410:BR63 RS08020
gene id: 1712410:BR63_RS08020
uniprot id: A0A7G6E2F6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1712410:BR63 RS18495
gene id: 1712410:BR63_RS18495
uniprot id: A0A7G6E7L9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS05270
gene id: 1712410:BR63_RS05270
uniprot id: A0A7G6E116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS18515
gene id: 1712410:BR63_RS18515
uniprot id: A0A7G6E7M3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1712410:BR63 RS09100
gene id: 1712410:BR63_RS09100
uniprot id: A0A7G6E2Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1712410:BR63 RS14855
gene id: 1712410:BR63_RS14855
uniprot id: A0A7G6E5T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1712410:BR63 RS05285
gene id: 1712410:BR63_RS05285
uniprot id: A0A7G6E119
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1712410:BR63 RS12200
gene id: 1712410:BR63_RS12200
uniprot id: A0A7G6E4J0
names: Similarity
messages: Belongs to the PemK/MazF family.

1712410:BR63 RS06730
gene id: 1712410:BR63_RS06730
uniprot id: A0A7G6E1T2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1712410:BR63 RS14180
gene id: 1712410:BR63_RS14180
uniprot id: A0A7G6E5H4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1712410:BR63 RS09850
gene id: 1712410:BR63_RS09850
uniprot id: A0A7G6E3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1712410:BR63 RS06805
gene id: 1712410:BR63_RS06805
uniprot id: A0A7G6E1U5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1712410:BR63 RS07770
gene id: 1712410:BR63_RS07770
uniprot id: A0A7G6E2B1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS06165
gene id: 1712410:BR63_RS06165
uniprot id: A0A7G6E1H5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1712410:BR63 RS02520
gene id: 1712410:BR63_RS02520
uniprot id: A0A7G6E863
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1712410:BR63 RS12500
gene id: 1712410:BR63_RS12500
uniprot id: A0A7G6E4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1712410:BR63 RS18080
gene id: 1712410:BR63_RS18080
uniprot id: A0A7G6E7D9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1712410:BR63 RS17885
gene id: 1712410:BR63_RS17885
uniprot id: A0A7G6E8U7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS08680
gene id: 1712410:BR63_RS08680
uniprot id: A0A7G6E2S6
names: Similarity
messages: Belongs to the IlvD/Edd family.

1712410:BR63 RS11430
gene id: 1712410:BR63_RS11430
uniprot id: A0A7G6E454
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1712410:BR63 RS04105
gene id: 1712410:BR63_RS04105
uniprot id: A0A7G6E0G4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1712410:BR63 RS05245
gene id: 1712410:BR63_RS05245
uniprot id: A0A7G6E111
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1712410:BR63 RS07425
gene id: 1712410:BR63_RS07425
uniprot id: A0A7G6E250
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1712410:BR63 RS06480
gene id: 1712410:BR63_RS06480
uniprot id: A0A7G6E1N5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1712410:BR63 RS05580
gene id: 1712410:BR63_RS05580
uniprot id: A0A7G6E171
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1712410:BR63 RS04835
gene id: 1712410:BR63_RS04835
uniprot id: A0A7G6E0T5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1712410:BR63 RS09985
gene id: 1712410:BR63_RS09985
uniprot id: A0A7G6E3E9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1712410:BR63 RS17105
gene id: 1712410:BR63_RS17105
uniprot id: A0A7G6E6W7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1712410:BR63 RS12540
gene id: 1712410:BR63_RS12540
uniprot id: A0A7G6E8L2
names: Similarity
messages: Belongs to the UPF0340 family.

1712410:BR63 RS09950
gene id: 1712410:BR63_RS09950
uniprot id: A0A7G6E3E2
names: Similarity
messages: Belongs to the UPF0749 family.

1712410:BR63 RS06895
gene id: 1712410:BR63_RS06895
uniprot id: A0A7G6E1W1
names: Similarity
messages: Belongs to the creatininase superfamily.

1712410:BR63 RS06190
gene id: 1712410:BR63_RS06190
uniprot id: A0A7G6E1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1712410:BR63 RS01035
gene id: 1712410:BR63_RS01035
uniprot id: A0A7G6DYX5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1712410:BR63 RS10550
gene id: 1712410:BR63_RS10550
uniprot id: A0A7G6E3P7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1712410:BR63 RS12475
gene id: 1712410:BR63_RS12475
uniprot id: A0A7G6E4P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1712410:BR63 RS17810
gene id: 1712410:BR63_RS17810
uniprot id: A0A7G6E790
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1712410:BR63 RS01135
gene id: 1712410:BR63_RS01135
uniprot id: A0A7G6DYZ3
names: Similarity
messages: Belongs to the AOR/FOR family.

1712410:BR63 RS07890
gene id: 1712410:BR63_RS07890
uniprot id: A0A7G6E2D1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1712410:BR63 RS12690
gene id: 1712410:BR63_RS12690
uniprot id: A0A7G6E4S7
names: Similarity
messages: Belongs to the RpoE family.

1712410:BR63 RS12010
gene id: 1712410:BR63_RS12010
uniprot id: A0A7G6E4G2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1712410:BR63 RS04920
gene id: 1712410:BR63_RS04920
uniprot id: A0A7G6E0V2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1712410:BR63 RS07285
gene id: 1712410:BR63_RS07285
uniprot id: A0A7G6E224
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1712410:BR63 RS14390
gene id: 1712410:BR63_RS14390
uniprot id: A0A7G6E5L1
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1712410:BR63 RS06085
gene id: 1712410:BR63_RS06085
uniprot id: A0A7G6E1G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1712410:BR63 RS01460
gene id: 1712410:BR63_RS01460
uniprot id: A0A7G6DZ49
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1712410:BR63 RS06890
gene id: 1712410:BR63_RS06890
uniprot id: A0A7G6E1W0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1712410:BR63 RS09090
gene id: 1712410:BR63_RS09090
uniprot id: A0A7G6E2Z6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1712410:BR63 RS12590
gene id: 1712410:BR63_RS12590
uniprot id: A0A7G6E4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS13045
gene id: 1712410:BR63_RS13045
uniprot id: A0A7G6E4Y7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1712410:BR63 RS13825
gene id: 1712410:BR63_RS13825
uniprot id: A0A7G6E5B0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1712410:BR63 RS05050
gene id: 1712410:BR63_RS05050
uniprot id: A0A7G6E0X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1712410:BR63 RS14190
gene id: 1712410:BR63_RS14190
uniprot id: A0A7G6E5H6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1712410:BR63 RS18440
gene id: 1712410:BR63_RS18440
uniprot id: A0A7G6E7K8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1712410:BR63 RS17900
gene id: 1712410:BR63_RS17900
uniprot id: A0A7G6E7A7
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS12885
gene id: 1712410:BR63_RS12885
uniprot id: A0A7G6E4W2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1712410:BR63 RS11840
gene id: 1712410:BR63_RS11840
uniprot id: A0A7G6E4C9
names: Similarity
messages: Belongs to the threonine synthase family.

1712410:BR63 RS14995
gene id: 1712410:BR63_RS14995
uniprot id: A0A7G6E5W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1712410:BR63 RS03770
gene id: 1712410:BR63_RS03770
uniprot id: A0A7G6E0A3
names: Similarity
messages: Belongs to the GSP E family.

1712410:BR63 RS08230
gene id: 1712410:BR63_RS08230
uniprot id: A0A7G6E2J2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS16805
gene id: 1712410:BR63_RS16805
uniprot id: A0A7G6E6S2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1712410:BR63 RS01865
gene id: 1712410:BR63_RS01865
uniprot id: A0A7G6DZC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1712410:BR63 RS13050
gene id: 1712410:BR63_RS13050
uniprot id: A0A7G6E4Y8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1712410:BR63 RS12640
gene id: 1712410:BR63_RS12640
uniprot id: A0A7G6E4R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1712410:BR63 RS10975
gene id: 1712410:BR63_RS10975
uniprot id: A0A7G6E3X3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1712410:BR63 RS10635
gene id: 1712410:BR63_RS10635
uniprot id: A0A7G6E3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1712410:BR63 RS17780
gene id: 1712410:BR63_RS17780
uniprot id: A0A7G6E785
names: Similarity
messages: Belongs to the fabD family.

1712410:BR63 RS06790
gene id: 1712410:BR63_RS06790
uniprot id: A0A7G6E1U3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1712410:BR63 RS02000
gene id: 1712410:BR63_RS02000
uniprot id: A0A7G6DZE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1712410:BR63 RS08985
gene id: 1712410:BR63_RS08985
uniprot id: A0A7G6E2X6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1712410:BR63 RS15930
gene id: 1712410:BR63_RS15930
uniprot id: A0A7G6E6B9
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS03845
gene id: 1712410:BR63_RS03845
uniprot id: A0A7G6E0B6
names: Similarity
messages: Belongs to the peptidase U62 family.

1712410:BR63 RS12080
gene id: 1712410:BR63_RS12080
uniprot id: A0A7G6E4G6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1712410:BR63 RS14440
gene id: 1712410:BR63_RS14440
uniprot id: A0A7G6E5L8
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS11850
gene id: 1712410:BR63_RS11850
uniprot id: A0A7G6E4D1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1712410:BR63 RS02410
gene id: 1712410:BR63_RS02410
uniprot id: A0A7G6DZL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1712410:BR63 RS01390
gene id: 1712410:BR63_RS01390
uniprot id: A0A7G6DZ36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1712410:BR63 RS07785
gene id: 1712410:BR63_RS07785
uniprot id: A0A7G6E2B4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1712410:BR63 RS08720
gene id: 1712410:BR63_RS08720
uniprot id: A0A7G6E2T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1712410:BR63 RS12505
gene id: 1712410:BR63_RS12505
uniprot id: A0A7G6E4P6
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS00160
gene id: 1712410:BR63_RS00160
uniprot id: A0A7G6DYH6
names: Similarity
messages: Belongs to the CdaR family.

1712410:BR63 RS08660
gene id: 1712410:BR63_RS08660
uniprot id: A0A7G6E2S2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1712410:BR63 RS07215
gene id: 1712410:BR63_RS07215
uniprot id: A0A7G6E210
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1712410:BR63 RS05180
gene id: 1712410:BR63_RS05180
uniprot id: A0A7G6E0Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1712410:BR63 RS15145
gene id: 1712410:BR63_RS15145
uniprot id: A0A7G6E5Y8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1712410:BR63 RS11560
gene id: 1712410:BR63_RS11560
uniprot id: A0A7G6E479
names: Similarity
messages: Belongs to the peptidase A31 family.

1712410:BR63 RS09835
gene id: 1712410:BR63_RS09835
uniprot id: A0A7G6E3C4
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

1712410:BR63 RS07380
gene id: 1712410:BR63_RS07380
uniprot id: A0A7G6E242
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1712410:BR63 RS15295
gene id: 1712410:BR63_RS15295
uniprot id: A0A7G6E614
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1712410:BR63 RS15035
gene id: 1712410:BR63_RS15035
uniprot id: A0A7G6E5W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1712410:BR63 RS05040
gene id: 1712410:BR63_RS05040
uniprot id: A0A7G6E0X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1712410:BR63 RS12015
gene id: 1712410:BR63_RS12015
uniprot id: A0A7G6E4G3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1712410:BR63 RS08470
gene id: 1712410:BR63_RS08470
uniprot id: A0A7G6E2N7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1712410:BR63 RS15135
gene id: 1712410:BR63_RS15135
uniprot id: A0A7G6E5Y6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1712410:BR63 RS10955
gene id: 1712410:BR63_RS10955
uniprot id: A0A7G6E3W9
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

1712410:BR63 RS13190
gene id: 1712410:BR63_RS13190
uniprot id: A0A7G6E510
names: Similarity
messages: Belongs to the DapA family.

1712410:BR63 RS07010
gene id: 1712410:BR63_RS07010
uniprot id: A0A7G6E1X6
names: Caution
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS02595
gene id: 1712410:BR63_RS02595
uniprot id: A0A7G6DZP0
names: Similarity
messages: Belongs to the RecJ family.

1712410:BR63 RS08880
gene id: 1712410:BR63_RS08880
uniprot id: A0A7G6E2V8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1712410:BR63 RS06340
gene id: 1712410:BR63_RS06340
uniprot id: A0A7G6E1K8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

1712410:BR63 RS13255
gene id: 1712410:BR63_RS13255
uniprot id: A0A7G6E521
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS04090
gene id: 1712410:BR63_RS04090
uniprot id: A0A7G6E0G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1712410:BR63 RS02380
gene id: 1712410:BR63_RS02380
uniprot id: A0A7G6DZK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1712410:BR63 RS18265
gene id: 1712410:BR63_RS18265
uniprot id: A0A7G6E7H6
names: Similarity
messages: Belongs to the EamA transporter family.

1712410:BR63 RS12340
gene id: 1712410:BR63_RS12340
uniprot id: A0A7G6E4L4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1712410:BR63 RS07410
gene id: 1712410:BR63_RS07410
uniprot id: A0A7G6E247
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS11475
gene id: 1712410:BR63_RS11475
uniprot id: A0A7G6E462
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1712410:BR63 RS16240
gene id: 1712410:BR63_RS16240
uniprot id: A0A7G6E6G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1712410:BR63 RS18940
gene id: 1712410:BR63_RS18940
uniprot id: A0A7G6E7U8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1712410:BR63 RS13930
gene id: 1712410:BR63_RS13930
uniprot id: A0A7G6E5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1712410:BR63 RS08415
gene id: 1712410:BR63_RS08415
uniprot id: A0A7G6E2M7
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1712410:BR63 RS06105
gene id: 1712410:BR63_RS06105
uniprot id: A0A7G6E1G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

1712410:BR63 RS06265
gene id: 1712410:BR63_RS06265
uniprot id: A0A7G6E1J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1712410:BR63 RS08045
gene id: 1712410:BR63_RS08045
uniprot id: A0A7G6E2G1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1712410:BR63 RS18695
gene id: 1712410:BR63_RS18695
uniprot id: A0A7G6E7Q4
names: Similarity
messages: Belongs to the Ahb/Nir family.

1712410:BR63 RS13465
gene id: 1712410:BR63_RS13465
uniprot id: A0A7G6E556
names: Similarity
messages: Belongs to the DSD1 family.

1712410:BR63 RS17790
gene id: 1712410:BR63_RS17790
uniprot id: A0A7G6E787
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1712410:BR63 RS15180
gene id: 1712410:BR63_RS15180
uniprot id: A0A7G6E5Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1712410:BR63 RS07190
gene id: 1712410:BR63_RS07190
uniprot id: A0A7G6E207
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1712410:BR63 RS14875
gene id: 1712410:BR63_RS14875
uniprot id: A0A7G6E5T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1712410:BR63 RS17505
gene id: 1712410:BR63_RS17505
uniprot id: A0A7G6E736
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1712410:BR63 RS13430
gene id: 1712410:BR63_RS13430
uniprot id: A0A7G6E549
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1712410:BR63 RS17915
gene id: 1712410:BR63_RS17915
uniprot id: A0A7G6E7B0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1712410:BR63 RS18760
gene id: 1712410:BR63_RS18760
uniprot id: A0A7G6E7R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS18720
gene id: 1712410:BR63_RS18720
uniprot id: A0A7G6E7Q7
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

1712410:BR63 RS19035
gene id: 1712410:BR63_RS19035
uniprot id: A0A7G6E7W7
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS13310
gene id: 1712410:BR63_RS13310
uniprot id: A0A7G6E530
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1712410:BR63 RS12575
gene id: 1712410:BR63_RS12575
uniprot id: A0A7G6E4Q8
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS04100
gene id: 1712410:BR63_RS04100
uniprot id: A0A7G6E0G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1712410:BR63 RS06345
gene id: 1712410:BR63_RS06345
uniprot id: A0A7G6E1K9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1712410:BR63 RS08370
gene id: 1712410:BR63_RS08370
uniprot id: A0A7G6E2L8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS07775
gene id: 1712410:BR63_RS07775
uniprot id: A0A7G6E2B2
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

1712410:BR63 RS08485
gene id: 1712410:BR63_RS08485
uniprot id: A0A7G6E2P0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1712410:BR63 RS12605
gene id: 1712410:BR63_RS12605
uniprot id: A0A7G6E4R3
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1712410:BR63 RS01050
gene id: 1712410:BR63_RS01050
uniprot id: A0A7G6DYX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1712410:BR63 RS14570
gene id: 1712410:BR63_RS14570
uniprot id: A0A7G6E5P2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1712410:BR63 RS06430
gene id: 1712410:BR63_RS06430
uniprot id: A0A7G6E1M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

1712410:BR63 RS16375
gene id: 1712410:BR63_RS16375
uniprot id: A0A7G6E6J3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1712410:BR63 RS01410
gene id: 1712410:BR63_RS01410
uniprot id: A0A7G6DZ40
names: Subunit
messages: Homodimer.

1712410:BR63 RS14800
gene id: 1712410:BR63_RS14800
uniprot id: A0A7G6E5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1712410:BR63 RS11950
gene id: 1712410:BR63_RS11950
uniprot id: A0A7G6E4F1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1712410:BR63 RS08905
gene id: 1712410:BR63_RS08905
uniprot id: A0A7G6E2W3
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS14700
gene id: 1712410:BR63_RS14700
uniprot id: A0A7G6E5R3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1712410:BR63 RS12560
gene id: 1712410:BR63_RS12560
uniprot id: A0A7G6E4Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1712410:BR63 RS06555
gene id: 1712410:BR63_RS06555
uniprot id: A0A7G6E1Q0
names: Similarity
messages: Belongs to the HupF/HypC family.

1712410:BR63 RS09550
gene id: 1712410:BR63_RS09550
uniprot id: A0A7G6E375
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1712410:BR63 RS14885
gene id: 1712410:BR63_RS14885
uniprot id: A0A7G6E5U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1712410:BR63 RS11725
gene id: 1712410:BR63_RS11725
uniprot id: A0A7G6E4A8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1712410:BR63 RS04445
gene id: 1712410:BR63_RS04445
uniprot id: A0A7G6E0M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1712410:BR63 RS02320
gene id: 1712410:BR63_RS02320
uniprot id: A0A7G6DZJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1712410:BR63 RS01870
gene id: 1712410:BR63_RS01870
uniprot id: A0A7G6DZC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1712410:BR63 RS17275
gene id: 1712410:BR63_RS17275
uniprot id: A0A7G6E6Z3
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS11780
gene id: 1712410:BR63_RS11780
uniprot id: A0A7G6E8K5
names: Similarity
messages: Belongs to the GSP E family.

1712410:BR63 RS15160
gene id: 1712410:BR63_RS15160
uniprot id: A0A7G6E5Z1
names: Similarity
messages: Belongs to the peptidase M20A family.

1712410:BR63 RS19055
gene id: 1712410:BR63_RS19055
uniprot id: A0A7G6E7W9
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1712410:BR63 RS00495
gene id: 1712410:BR63_RS00495
uniprot id: A0A7G6DYN2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1712410:BR63 RS15155
gene id: 1712410:BR63_RS15155
uniprot id: A0A7G6E5Z0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS06515
gene id: 1712410:BR63_RS06515
uniprot id: A0A7G6E1P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1712410:BR63 RS14320
gene id: 1712410:BR63_RS14320
uniprot id: A0A7G6E5J8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS14985
gene id: 1712410:BR63_RS14985
uniprot id: A0A7G6E5W0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1712410:BR63 RS07070
gene id: 1712410:BR63_RS07070
uniprot id: A0A7G6E1Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS11915
gene id: 1712410:BR63_RS11915
uniprot id: A0A7G6E4E4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1712410:BR63 RS13330
gene id: 1712410:BR63_RS13330
uniprot id: A0A7G6E534
names: Similarity
messages: Belongs to the AOR/FOR family.

1712410:BR63 RS04255
gene id: 1712410:BR63_RS04255
uniprot id: A0A7G6E0J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1712410:BR63 RS02855
gene id: 1712410:BR63_RS02855
uniprot id: A0A7G6DZT8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1712410:BR63 RS14575
gene id: 1712410:BR63_RS14575
uniprot id: A0A7G6E5P3
names: Similarity
messages: Belongs to the DHPS family.

1712410:BR63 RS18040
gene id: 1712410:BR63_RS18040
uniprot id: A0A7G6E7D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1712410:BR63 RS08675
gene id: 1712410:BR63_RS08675
uniprot id: A0A7G6E2S5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1712410:BR63 RS02355
gene id: 1712410:BR63_RS02355
uniprot id: A0A7G6DZK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS08685
gene id: 1712410:BR63_RS08685
uniprot id: A0A7G6E2S7
names: Similarity
messages: Belongs to the FGGY kinase family.

1712410:BR63 RS11605
gene id: 1712410:BR63_RS11605
uniprot id: A0A7G6E488
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1712410:BR63 RS15510
gene id: 1712410:BR63_RS15510
uniprot id: A0A7G6E649
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS18770
gene id: 1712410:BR63_RS18770
uniprot id: A0A7G6E7R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1712410:BR63 RS02055
gene id: 1712410:BR63_RS02055
uniprot id: A0A7G6DZF4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1712410:BR63 RS15985
gene id: 1712410:BR63_RS15985
uniprot id: A0A7G6E6D0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1712410:BR63 RS00090
gene id: 1712410:BR63_RS00090
uniprot id: A0A7G6E816
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1712410:BR63 RS04240
gene id: 1712410:BR63_RS04240
uniprot id: A0A7G6E0I7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

1712410:BR63 RS04940
gene id: 1712410:BR63_RS04940
uniprot id: A0A7G6E0V5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS00100
gene id: 1712410:BR63_RS00100
uniprot id: A0A7G6DYG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1712410:BR63 RS01015
gene id: 1712410:BR63_RS01015
uniprot id: A0A7G6DYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS01170
gene id: 1712410:BR63_RS01170
uniprot id: A0A7G6DZ00
names: Similarity
messages: Belongs to the glutamine synthetase family.

1712410:BR63 RS09855
gene id: 1712410:BR63_RS09855
uniprot id: A0A7G6E3C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1712410:BR63 RS08585
gene id: 1712410:BR63_RS08585
uniprot id: A0A7G6E2Q8
names: Similarity
messages: Belongs to the UPF0234 family.

1712410:BR63 RS10320
gene id: 1712410:BR63_RS10320
uniprot id: A0A7G6E3K8
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS03050
gene id: 1712410:BR63_RS03050
uniprot id: A0A7G6DZX1
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS17935
gene id: 1712410:BR63_RS17935
uniprot id: A0A7G6E6E3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1712410:BR63 RS18390
gene id: 1712410:BR63_RS18390
uniprot id: A0A7G6E7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712410:BR63 RS00120
gene id: 1712410:BR63_RS00120
uniprot id: A0A7G6DYG8
names: Similarity
messages: Belongs to the NadC/ModD family.

1712410:BR63 RS14350
gene id: 1712410:BR63_RS14350
uniprot id: A0A7G6E5K3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1712410:BR63 RS02600
gene id: 1712410:BR63_RS02600
uniprot id: A0A7G6DZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1712410:BR63 RS00655
gene id: 1712410:BR63_RS00655
uniprot id: A0A7G6DYQ9
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS09330
gene id: 1712410:BR63_RS09330
uniprot id: A0A7G6E337
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712410:BR63 RS06880
gene id: 1712410:BR63_RS06880
uniprot id: A0A7G6E1V8
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS10825
gene id: 1712410:BR63_RS10825
uniprot id: A0A7G6E3U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1712410:BR63 RS06140
gene id: 1712410:BR63_RS06140
uniprot id: A0A7G6E1H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1712410:BR63 RS18980
gene id: 1712410:BR63_RS18980
uniprot id: A0A7G6E7V6
names: Subcellular Location Annotation
messages: Membrane

1712410:BR63 RS03775
gene id: 1712410:BR63_RS03775
uniprot id: A0A7G6E0A4
names: Similarity
messages: Belongs to the GSP E family.

1712410:BR63 RS12465
gene id: 1712410:BR63_RS12465
uniprot id: A0A7G6E4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1712410:BR63 RS02295
gene id: 1712410:BR63_RS02295
uniprot id: A0A7G6DZJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1712410:BR63 RS05430
gene id: 1712410:BR63_RS05430
uniprot id: A0A7G6E145
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1712410:BR63 RS06550
gene id: 1712410:BR63_RS06550
uniprot id: A0A7G6E1P9
names: Similarity
messages: Belongs to the HypD family.

1712410:BR63 RS09575
gene id: 1712410:BR63_RS09575
uniprot id: A0A7G6E380
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1712410:BR63 RS01980
gene id: 1712410:BR63_RS01980
uniprot id: A0A7G6DZE0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1712410:BR63 RS13495
gene id: 1712410:BR63_RS13495
uniprot id: A0A7G6E562
names: Similarity
messages: Belongs to the ParB family.

1712410:BR63 RS03475
gene id: 1712410:BR63_RS03475
uniprot id: A0A7G6E054
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1712410:BR63 RS10580
gene id: 1712410:BR63_RS10580
uniprot id: A0A7G6E3Q2
names: Similarity
messages: Belongs to the HypD family.

1712410:BR63 RS09665
gene id: 1712410:BR63_RS09665
uniprot id: A0A7G6E395
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1712410:BR63 RS02805
gene id: 1712410:BR63_RS02805
uniprot id: A0A7G6DZS8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.