1679721:SD1D RS11065
gene id: 1679721:SD1D_RS11065
uniprot id: A0A0K8J8V5
names: Similarity
messages: Belongs to the UPF0473 family.

1679721:SD1D RS04300
gene id: 1679721:SD1D_RS04300
uniprot id: A0A0K8J4Z9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1679721:SD1D RS09365
gene id: 1679721:SD1D_RS09365
uniprot id: A0A0K8J709
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1679721:SD1D RS00660
gene id: 1679721:SD1D_RS00660
uniprot id: A0A0K8J2W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS07845
gene id: 1679721:SD1D_RS07845
uniprot id: A0A0K8J6S5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1679721:SD1D RS11960
gene id: 1679721:SD1D_RS11960
uniprot id: A0A0K8J9I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1679721:SD1D RS02065
gene id: 1679721:SD1D_RS02065
uniprot id: A0A0K8J3S0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1679721:SD1D RS11455
gene id: 1679721:SD1D_RS11455
uniprot id: A0A0K8J945
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1679721:SD1D RS10080
gene id: 1679721:SD1D_RS10080
uniprot id: A0A0K8J7N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1679721:SD1D RS08605
gene id: 1679721:SD1D_RS08605
uniprot id: A0A0K8J7I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1679721:SD1D RS09665
gene id: 1679721:SD1D_RS09665
uniprot id: A0A0K8J7Q8
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS06505
gene id: 1679721:SD1D_RS06505
uniprot id: A0A0K8J697
names: Similarity
messages: Belongs to the ArsC family.

1679721:SD1D RS04155
gene id: 1679721:SD1D_RS04155
uniprot id: A0A0K8J4V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1679721:SD1D RS10160
gene id: 1679721:SD1D_RS10160
uniprot id: A0A0K8J7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1679721:SD1D RS02810
gene id: 1679721:SD1D_RS02810
uniprot id: A0A0K8J3Q3
names: Similarity
messages: Belongs to the peptidase S66 family.

1679721:SD1D RS09490
gene id: 1679721:SD1D_RS09490
uniprot id: A0A0K8J7D8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1679721:SD1D RS09740
gene id: 1679721:SD1D_RS09740
uniprot id: A0A0K8J7S0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS08200
gene id: 1679721:SD1D_RS08200
uniprot id: A0A0K8J7B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1679721:SD1D RS10015
gene id: 1679721:SD1D_RS10015
uniprot id: A0A0K8J881
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1679721:SD1D RS09100
gene id: 1679721:SD1D_RS09100
uniprot id: A0A0K8J7R1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1679721:SD1D RS05130
gene id: 1679721:SD1D_RS05130
uniprot id: A0A0K8J527
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1679721:SD1D RS12245
gene id: 1679721:SD1D_RS12245
uniprot id: A0A0K8J256
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1679721:SD1D RS12030
gene id: 1679721:SD1D_RS12030
uniprot id: A0A0K8J8J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1679721:SD1D RS06990
gene id: 1679721:SD1D_RS06990
uniprot id: A0A0K8J658
names: Similarity
messages: Belongs to the UPF0236 family.

1679721:SD1D RS02125
gene id: 1679721:SD1D_RS02125
uniprot id: A0A0K8J3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1679721:SD1D RS05385
gene id: 1679721:SD1D_RS05385
uniprot id: A0A0K8J5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1679721:SD1D RS08665
gene id: 1679721:SD1D_RS08665
uniprot id: A0A0K8J766
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1679721:SD1D RS01635
gene id: 1679721:SD1D_RS01635
uniprot id: A0A0K8J3D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1679721:SD1D RS05755
gene id: 1679721:SD1D_RS05755
uniprot id: A0A0K8J5U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1679721:SD1D RS05795
gene id: 1679721:SD1D_RS05795
uniprot id: A0A0K8J4Y1
names: Similarity
messages: Belongs to the ArsC family.

1679721:SD1D RS08260
gene id: 1679721:SD1D_RS08260
uniprot id: A0A0K8J707
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1679721:SD1D RS10840
gene id: 1679721:SD1D_RS10840
uniprot id: A0A0K8J8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1679721:SD1D RS03105
gene id: 1679721:SD1D_RS03105
uniprot id: A0A0K8J4E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1679721:SD1D RS01485
gene id: 1679721:SD1D_RS01485
uniprot id: A0A0K8J3F1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1679721:SD1D RS12050
gene id: 1679721:SD1D_RS12050
uniprot id: A0A0K8J8L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1679721:SD1D RS00115
gene id: 1679721:SD1D_RS00115
uniprot id: A0A0K8J261
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1679721:SD1D RS04170
gene id: 1679721:SD1D_RS04170
uniprot id: A0A0K8J4G8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane

1679721:SD1D RS05340
gene id: 1679721:SD1D_RS05340
uniprot id: A0A0K8J567
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1679721:SD1D RS01350
gene id: 1679721:SD1D_RS01350
uniprot id: A0A0K8J2T4
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

1679721:SD1D RS00120
gene id: 1679721:SD1D_RS00120
uniprot id: A0A0K8J2P4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS12040
gene id: 1679721:SD1D_RS12040
uniprot id: A0A0K8J9K0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS05030
gene id: 1679721:SD1D_RS05030
uniprot id: A0A0K8J5D6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1679721:SD1D RS02945
gene id: 1679721:SD1D_RS02945
uniprot id: A0A0K8J483
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS06710
gene id: 1679721:SD1D_RS06710
uniprot id: A0A0K8J683
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1679721:SD1D RS03500
gene id: 1679721:SD1D_RS03500
uniprot id: A0A0K8J4L6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1679721:SD1D RS02725
gene id: 1679721:SD1D_RS02725
uniprot id: A0A0K8J3M3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1679721:SD1D RS05120
gene id: 1679721:SD1D_RS05120
uniprot id: A0A0K8J520
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

1679721:SD1D RS07070
gene id: 1679721:SD1D_RS07070
uniprot id: A0A0K8J6E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS02285
gene id: 1679721:SD1D_RS02285
uniprot id: A0A0K8J3U9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1679721:SD1D RS08120
gene id: 1679721:SD1D_RS08120
uniprot id: A0A0K8J7A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1679721:SD1D RS04090
gene id: 1679721:SD1D_RS04090
uniprot id: A0A0K8J3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

1679721:SD1D RS04260
gene id: 1679721:SD1D_RS04260
uniprot id: A0A0K8J4K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1679721:SD1D RS11820
gene id: 1679721:SD1D_RS11820
uniprot id: A0A0K8J8S2
names: Similarity
messages: Belongs to the CarB family.

1679721:SD1D RS08035
gene id: 1679721:SD1D_RS08035
uniprot id: A0A0K8J6Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

1679721:SD1D RS00770
gene id: 1679721:SD1D_RS00770
uniprot id: A0A0K8J245
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1679721:SD1D RS02055
gene id: 1679721:SD1D_RS02055
uniprot id: A0A0K8J2U7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1679721:SD1D RS10980
gene id: 1679721:SD1D_RS10980
uniprot id: A0A0K8J821
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1679721:SD1D RS08535
gene id: 1679721:SD1D_RS08535
uniprot id: A0A0K8J7E5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1679721:SD1D RS03860
gene id: 1679721:SD1D_RS03860
uniprot id: A0A0K8J3U6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1679721:SD1D RS03125
gene id: 1679721:SD1D_RS03125
uniprot id: A0A0K8J3Y6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1679721:SD1D RS08205
gene id: 1679721:SD1D_RS08205
uniprot id: A0A0K8J767
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1679721:SD1D RS08000
gene id: 1679721:SD1D_RS08000
uniprot id: A0A0K8J714
names: Similarity
messages: Belongs to the TrpF family.

1679721:SD1D RS01795
gene id: 1679721:SD1D_RS01795
uniprot id: A0A0K8J353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS05660
gene id: 1679721:SD1D_RS05660
uniprot id: A0A0K8J5Q6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1679721:SD1D RS10650
gene id: 1679721:SD1D_RS10650
uniprot id: A0A0K8J8U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1679721:SD1D RS05690
gene id: 1679721:SD1D_RS05690
uniprot id: A0A0K8J5F3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1679721:SD1D RS02870
gene id: 1679721:SD1D_RS02870
uniprot id: A0A0K8J473
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1679721:SD1D RS11385
gene id: 1679721:SD1D_RS11385
uniprot id: A0A0K8J946
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1679721:SD1D RS11330
gene id: 1679721:SD1D_RS11330
uniprot id: A0A0K8J883
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1679721:SD1D RS04050
gene id: 1679721:SD1D_RS04050
uniprot id: A0A0K8J4V2
names: Similarity
messages: Belongs to the transpeptidase family.

1679721:SD1D RS05535
gene id: 1679721:SD1D_RS05535
uniprot id: A0A0K8J5N2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS10975
gene id: 1679721:SD1D_RS10975
uniprot id: A0A0K8J8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1679721:SD1D RS05650
gene id: 1679721:SD1D_RS05650
uniprot id: A0A0K8J5E7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1679721:SD1D RS00465
gene id: 1679721:SD1D_RS00465
uniprot id: A0A0K8J2E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1679721:SD1D RS07905
gene id: 1679721:SD1D_RS07905
uniprot id: A0A0K8J6L1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1679721:SD1D RS05950
gene id: 1679721:SD1D_RS05950
uniprot id: A0A0K8J5Y6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS03830
gene id: 1679721:SD1D_RS03830
uniprot id: A0A0K8J496
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS04560
gene id: 1679721:SD1D_RS04560
uniprot id: A0A0K8J539
names: Similarity
messages: Belongs to the ribF family.

1679721:SD1D RS11550
gene id: 1679721:SD1D_RS11550
uniprot id: A0A0K8J877
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1679721:SD1D RS03335
gene id: 1679721:SD1D_RS03335
uniprot id: A0A0K8J412
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS00210
gene id: 1679721:SD1D_RS00210
uniprot id: A0A0K8J1S2
names: Similarity
messages: Belongs to the GSP E family.

1679721:SD1D RS09220
gene id: 1679721:SD1D_RS09220
uniprot id: A0A0K8J7T0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1679721:SD1D RS00365
gene id: 1679721:SD1D_RS00365
uniprot id: A0A0K8J2B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1679721:SD1D RS10470
gene id: 1679721:SD1D_RS10470
uniprot id: A0A0K8J8I1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1679721:SD1D RS11175
gene id: 1679721:SD1D_RS11175
uniprot id: A0A0K8J853
names: Similarity
messages: Belongs to the UPF0236 family.

1679721:SD1D RS02820
gene id: 1679721:SD1D_RS02820
uniprot id: A0A0K8J432
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1679721:SD1D RS05270
gene id: 1679721:SD1D_RS05270
uniprot id: A0A0K8J550
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS05615
gene id: 1679721:SD1D_RS05615
uniprot id: A0A0K8J5D8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1679721:SD1D RS09310
gene id: 1679721:SD1D_RS09310
uniprot id: A0A0K8J700
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1679721:SD1D RS02865
gene id: 1679721:SD1D_RS02865
uniprot id: A0A0K8J3R2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS10530
gene id: 1679721:SD1D_RS10530
uniprot id: A0A0K8J8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS05305
gene id: 1679721:SD1D_RS05305
uniprot id: A0A0K8J564
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1679721:SD1D RS10915
gene id: 1679721:SD1D_RS10915
uniprot id: A0A0K8J8S6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1679721:SD1D RS04525
gene id: 1679721:SD1D_RS04525
uniprot id: A0A0K8J4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1679721:SD1D RS11145
gene id: 1679721:SD1D_RS11145
uniprot id: A0A0K8J8I7
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

1679721:SD1D RS06205
gene id: 1679721:SD1D_RS06205
uniprot id: A0A0K8J5P9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1679721:SD1D RS04950
gene id: 1679721:SD1D_RS04950
uniprot id: A0A0K8J4Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1679721:SD1D RS09930
gene id: 1679721:SD1D_RS09930
uniprot id: A0A0K8J7W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1679721:SD1D RS04485
gene id: 1679721:SD1D_RS04485
uniprot id: A0A0K8J525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS01960
gene id: 1679721:SD1D_RS01960
uniprot id: A0A0K8J357
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1679721:SD1D RS04910
gene id: 1679721:SD1D_RS04910
uniprot id: A0A0K8J599
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1679721:SD1D RS04225
gene id: 1679721:SD1D_RS04225
uniprot id: A0A0K8J4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1679721:SD1D RS08525
gene id: 1679721:SD1D_RS08525
uniprot id: A0A0K8J6M3
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS01715
gene id: 1679721:SD1D_RS01715
uniprot id: A0A0K8J3E6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1679721:SD1D RS11865
gene id: 1679721:SD1D_RS11865
uniprot id: A0A0K8J8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1679721:SD1D RS11025
gene id: 1679721:SD1D_RS11025
uniprot id: A0A0K8J8G8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1679721:SD1D RS05215
gene id: 1679721:SD1D_RS05215
uniprot id: A0A0K8J5G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1679721:SD1D RS11355
gene id: 1679721:SD1D_RS11355
uniprot id: A0A0K8J841
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1679721:SD1D RS06805
gene id: 1679721:SD1D_RS06805
uniprot id: A0A0K8J622
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1679721:SD1D RS10275
gene id: 1679721:SD1D_RS10275
uniprot id: A0A0K8J7S3
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1679721:SD1D RS02050
gene id: 1679721:SD1D_RS02050
uniprot id: A0A0K8J3A0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS10855
gene id: 1679721:SD1D_RS10855
uniprot id: A0A0K8J802
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1679721:SD1D RS04545
gene id: 1679721:SD1D_RS04545
uniprot id: A0A0K8J472
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1679721:SD1D RS00360
gene id: 1679721:SD1D_RS00360
uniprot id: A0A0K8J1V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1679721:SD1D RS04385
gene id: 1679721:SD1D_RS04385
uniprot id: A0A0K8J4N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1679721:SD1D RS02735
gene id: 1679721:SD1D_RS02735
uniprot id: A0A0K8J3N7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1679721:SD1D RS02780
gene id: 1679721:SD1D_RS02780
uniprot id: A0A0K8J399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS08805
gene id: 1679721:SD1D_RS08805
uniprot id: A0A0K8J785
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1679721:SD1D RS05070
gene id: 1679721:SD1D_RS05070
uniprot id: A0A0K8J4H0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1679721:SD1D RS06680
gene id: 1679721:SD1D_RS06680
uniprot id: A0A0K8J6D2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1679721:SD1D RS08675
gene id: 1679721:SD1D_RS08675
uniprot id: A0A0K8J6P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1679721:SD1D RS06690
gene id: 1679721:SD1D_RS06690
uniprot id: A0A0K8J5Z5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS06740
gene id: 1679721:SD1D_RS06740
uniprot id: A0A0K8J605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS07895
gene id: 1679721:SD1D_RS07895
uniprot id: A0A0K8J6X9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1679721:SD1D RS04010
gene id: 1679721:SD1D_RS04010
uniprot id: A0A0K8J4F1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1679721:SD1D RS05440
gene id: 1679721:SD1D_RS05440
uniprot id: A0A0K8J5A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1679721:SD1D RS03685
gene id: 1679721:SD1D_RS03685
uniprot id: A0A0K8J471
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS03900
gene id: 1679721:SD1D_RS03900
uniprot id: A0A0K8J4R2
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS05515
gene id: 1679721:SD1D_RS05515
uniprot id: A0A0K8J5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1679721:SD1D RS08590
gene id: 1679721:SD1D_RS08590
uniprot id: A0A0K8J752
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1679721:SD1D RS10535
gene id: 1679721:SD1D_RS10535
uniprot id: A0A0K8J7X6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1679721:SD1D RS04265
gene id: 1679721:SD1D_RS04265
uniprot id: A0A0K8J426
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1679721:SD1D RS08750
gene id: 1679721:SD1D_RS08750
uniprot id: A0A0K8J7L1
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS07870
gene id: 1679721:SD1D_RS07870
uniprot id: A0A0K8J6T0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1679721:SD1D RS04850
gene id: 1679721:SD1D_RS04850
uniprot id: A0A0K8J4X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1679721:SD1D RS05930
gene id: 1679721:SD1D_RS05930
uniprot id: A0A0K8J5V7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1679721:SD1D RS02535
gene id: 1679721:SD1D_RS02535
uniprot id: A0A0K8J409
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1679721:SD1D RS07795
gene id: 1679721:SD1D_RS07795
uniprot id: A0A0K8J6R6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1679721:SD1D RS05705
gene id: 1679721:SD1D_RS05705
uniprot id: A0A0K8J5T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1679721:SD1D RS03710
gene id: 1679721:SD1D_RS03710
uniprot id: A0A0K8J475
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1679721:SD1D RS00815
gene id: 1679721:SD1D_RS00815
uniprot id: A0A0K8J2N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1679721:SD1D RS05715
gene id: 1679721:SD1D_RS05715
uniprot id: A0A0K8J5F8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1679721:SD1D RS10565
gene id: 1679721:SD1D_RS10565
uniprot id: A0A0K8J7P5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1679721:SD1D RS03155
gene id: 1679721:SD1D_RS03155
uniprot id: A0A0K8J4F2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1679721:SD1D RS02880
gene id: 1679721:SD1D_RS02880
uniprot id: A0A0K8J3Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1679721:SD1D RS09595
gene id: 1679721:SD1D_RS09595
uniprot id: A0A0K8J7F9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1679721:SD1D RS03395
gene id: 1679721:SD1D_RS03395
uniprot id: A0A0K8J434
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

1679721:SD1D RS08025
gene id: 1679721:SD1D_RS08025
uniprot id: A0A0K8J716
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1679721:SD1D RS00855
gene id: 1679721:SD1D_RS00855
uniprot id: A0A0K8J2Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1679721:SD1D RS06155
gene id: 1679721:SD1D_RS06155
uniprot id: A0A0K8J5P0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1679721:SD1D RS04270
gene id: 1679721:SD1D_RS04270
uniprot id: A0A0K8J4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1679721:SD1D RS08610
gene id: 1679721:SD1D_RS08610
uniprot id: A0A0K8J7G0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1679721:SD1D RS07890
gene id: 1679721:SD1D_RS07890
uniprot id: A0A0K8J6X0
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS11660
gene id: 1679721:SD1D_RS11660
uniprot id: A0A0K8J9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1679721:SD1D RS02190
gene id: 1679721:SD1D_RS02190
uniprot id: A0A0K8J3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS00525
gene id: 1679721:SD1D_RS00525
uniprot id: A0A0K8J2U8
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS07130
gene id: 1679721:SD1D_RS07130
uniprot id: A0A0K8J5M5
names: Similarity
messages: Belongs to the peptidase S11 family.

1679721:SD1D RS11070
gene id: 1679721:SD1D_RS11070
uniprot id: A0A0K8J8Z9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1679721:SD1D RS02185
gene id: 1679721:SD1D_RS02185
uniprot id: A0A0K8J2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS06775
gene id: 1679721:SD1D_RS06775
uniprot id: A0A0K8J618
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1679721:SD1D RS05180
gene id: 1679721:SD1D_RS05180
uniprot id: A0A0K8J538
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1679721:SD1D RS10805
gene id: 1679721:SD1D_RS10805
uniprot id: A0A0K8J7Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1679721:SD1D RS04215
gene id: 1679721:SD1D_RS04215
uniprot id: A0A0K8J415
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1679721:SD1D RS00840
gene id: 1679721:SD1D_RS00840
uniprot id: A0A0K8J258
names: Similarity
messages: Belongs to the peptidase M29 family.

1679721:SD1D RS01570
gene id: 1679721:SD1D_RS01570
uniprot id: A0A0K8J2K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1679721:SD1D RS11290
gene id: 1679721:SD1D_RS11290
uniprot id: A0A0K8J658
names: Similarity
messages: Belongs to the UPF0236 family.

1679721:SD1D RS11975
gene id: 1679721:SD1D_RS11975
uniprot id: A0A0K8J8I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1679721:SD1D RS08080
gene id: 1679721:SD1D_RS08080
uniprot id: A0A0K8J6Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1679721:SD1D RS01160
gene id: 1679721:SD1D_RS01160
uniprot id: A0A0K8J394
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1679721:SD1D RS11835
gene id: 1679721:SD1D_RS11835
uniprot id: A0A0K8J9G9
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1679721:SD1D RS05160
gene id: 1679721:SD1D_RS05160
uniprot id: A0A0K8J5G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1679721:SD1D RS04465
gene id: 1679721:SD1D_RS04465
uniprot id: A0A0K8J4P4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1679721:SD1D RS01675
gene id: 1679721:SD1D_RS01675
uniprot id: A0A0K8J2Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1679721:SD1D RS06590
gene id: 1679721:SD1D_RS06590
uniprot id: A0A0K8J5B8
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS05435
gene id: 1679721:SD1D_RS05435
uniprot id: A0A0K8J5L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1679721:SD1D RS11565
gene id: 1679721:SD1D_RS11565
uniprot id: A0A0K8J8M7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1679721:SD1D RS01695
gene id: 1679721:SD1D_RS01695
uniprot id: A0A0K8J333
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1679721:SD1D RS11930
gene id: 1679721:SD1D_RS11930
uniprot id: A0A0K8J9C8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS05500
gene id: 1679721:SD1D_RS05500
uniprot id: A0A0K8J5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1679721:SD1D RS09050
gene id: 1679721:SD1D_RS09050
uniprot id: A0A0K8J745
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1679721:SD1D RS11650
gene id: 1679721:SD1D_RS11650
uniprot id: A0A0K8J895
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1679721:SD1D RS04990
gene id: 1679721:SD1D_RS04990
uniprot id: A0A0K8J4Z5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1679721:SD1D RS07345
gene id: 1679721:SD1D_RS07345
uniprot id: A0A0K8J6G9
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS02340
gene id: 1679721:SD1D_RS02340
uniprot id: A0A0K8J3T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS00280
gene id: 1679721:SD1D_RS00280
uniprot id: A0A0K8J2D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS00640
gene id: 1679721:SD1D_RS00640
uniprot id: A0A0K8J2K5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS08570
gene id: 1679721:SD1D_RS08570
uniprot id: A0A0K8J6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1679721:SD1D RS04905
gene id: 1679721:SD1D_RS04905
uniprot id: A0A0K8J5A8
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS09260
gene id: 1679721:SD1D_RS09260
uniprot id: A0A0K8J6Z4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS07830
gene id: 1679721:SD1D_RS07830
uniprot id: A0A0K8J619
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1679721:SD1D RS01455
gene id: 1679721:SD1D_RS01455
uniprot id: A0A0K8J2U9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1679721:SD1D RS05695
gene id: 1679721:SD1D_RS05695
uniprot id: A0A0K8J4W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1679721:SD1D RS03535
gene id: 1679721:SD1D_RS03535
uniprot id: A0A0K8J450
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1679721:SD1D RS02910
gene id: 1679721:SD1D_RS02910
uniprot id: A0A0K8J3C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1679721:SD1D RS06720
gene id: 1679721:SD1D_RS06720
uniprot id: A0A0K8J5E4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1679721:SD1D RS12005
gene id: 1679721:SD1D_RS12005
uniprot id: A0A0K8J8I6
names: Similarity
messages: Belongs to the ParB family.

1679721:SD1D RS05485
gene id: 1679721:SD1D_RS05485
uniprot id: A0A0K8J5M7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1679721:SD1D RS08735
gene id: 1679721:SD1D_RS08735
uniprot id: A0A0K8J776
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1679721:SD1D RS04790
gene id: 1679721:SD1D_RS04790
uniprot id: A0A0K8J4U7
names: Similarity
messages: Belongs to the DtxR/MntR family.

1679721:SD1D RS04395
gene id: 1679721:SD1D_RS04395
uniprot id: A0A0K8J4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1679721:SD1D RS02515
gene id: 1679721:SD1D_RS02515
uniprot id: A0A0K8J3W0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1679721:SD1D RS05190
gene id: 1679721:SD1D_RS05190
uniprot id: A0A0K8J5F5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1679721:SD1D RS02240
gene id: 1679721:SD1D_RS02240
uniprot id: A0A0K8J3U3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS05770
gene id: 1679721:SD1D_RS05770
uniprot id: A0A0K8J4X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1679721:SD1D RS09180
gene id: 1679721:SD1D_RS09180
uniprot id: A0A0K8J768
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1679721:SD1D RS05090
gene id: 1679721:SD1D_RS05090
uniprot id: A0A0K8J515
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1679721:SD1D RS02475
gene id: 1679721:SD1D_RS02475
uniprot id: A0A0K8J337
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1679721:SD1D RS00455
gene id: 1679721:SD1D_RS00455
uniprot id: A0A0K8J2I2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1679721:SD1D RS03100
gene id: 1679721:SD1D_RS03100
uniprot id: A0A0K8J3Y2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS01625
gene id: 1679721:SD1D_RS01625
uniprot id: A0A0K8J2Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1679721:SD1D RS04870
gene id: 1679721:SD1D_RS04870
uniprot id: A0A0K8J4D1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1679721:SD1D RS10510
gene id: 1679721:SD1D_RS10510
uniprot id: A0A0K8J7X0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1679721:SD1D RS04380
gene id: 1679721:SD1D_RS04380
uniprot id: A0A0K8J506
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS10335
gene id: 1679721:SD1D_RS10335
uniprot id: A0A0K8J7H4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1679721:SD1D RS11170
gene id: 1679721:SD1D_RS11170
uniprot id: A0A0K8J8I9
names: Similarity
messages: Belongs to the Gram-positive plasmids replication protein type 1 family.

1679721:SD1D RS00860
gene id: 1679721:SD1D_RS00860
uniprot id: A0A0K8J2P0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS04985
gene id: 1679721:SD1D_RS04985
uniprot id: A0A0K8J5A9
names: Similarity
messages: Belongs to the GerABKA family.

1679721:SD1D RS06315
gene id: 1679721:SD1D_RS06315
uniprot id: A0A0K8J5S1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS08680
gene id: 1679721:SD1D_RS08680
uniprot id: A0A0K8J7J8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1679721:SD1D RS09465
gene id: 1679721:SD1D_RS09465
uniprot id: A0A0K8J7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1679721:SD1D RS06405
gene id: 1679721:SD1D_RS06405
uniprot id: A0A0K8J5U0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1679721:SD1D RS04415
gene id: 1679721:SD1D_RS04415
uniprot id: A0A0K8J451
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1679721:SD1D RS01855
gene id: 1679721:SD1D_RS01855
uniprot id: A0A0K8J336
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1679721:SD1D RS06060
gene id: 1679721:SD1D_RS06060
uniprot id: A0A0K8J528
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1679721:SD1D RS01815
gene id: 1679721:SD1D_RS01815
uniprot id: A0A0K8J3G1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1679721:SD1D RS06750
gene id: 1679721:SD1D_RS06750
uniprot id: A0A0K8J612
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1679721:SD1D RS08615
gene id: 1679721:SD1D_RS08615
uniprot id: A0A0K8J757
names: Similarity
messages: Belongs to the asp23 family.

1679721:SD1D RS05220
gene id: 1679721:SD1D_RS05220
uniprot id: A0A0K8J541
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1679721:SD1D RS02275
gene id: 1679721:SD1D_RS02275
uniprot id: A0A0K8J2Z1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1679721:SD1D RS10900
gene id: 1679721:SD1D_RS10900
uniprot id: A0A0K8J8F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1679721:SD1D RS00035
gene id: 1679721:SD1D_RS00035
uniprot id: A0A0K8J255
names: Similarity
messages: Belongs to the class-I fumarase family.

1679721:SD1D RS00940
gene id: 1679721:SD1D_RS00940
uniprot id: A0A0K8J2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1679721:SD1D RS06560
gene id: 1679721:SD1D_RS06560
uniprot id: A0A0K8J668
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1679721:SD1D RS05230
gene id: 1679721:SD1D_RS05230
uniprot id: A0A0K8J549
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1679721:SD1D RS04445
gene id: 1679721:SD1D_RS04445
uniprot id: A0A0K8J455
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1679721:SD1D RS06630
gene id: 1679721:SD1D_RS06630
uniprot id: A0A0K8J6C2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1679721:SD1D RS10575
gene id: 1679721:SD1D_RS10575
uniprot id: A0A0K8J8S8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1679721:SD1D RS04355
gene id: 1679721:SD1D_RS04355
uniprot id: A0A0K8J4Z8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1679721:SD1D RS07995
gene id: 1679721:SD1D_RS07995
uniprot id: A0A0K8J758
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1679721:SD1D RS04175
gene id: 1679721:SD1D_RS04175
uniprot id: A0A0K8J4X4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1679721:SD1D RS07955
gene id: 1679721:SD1D_RS07955
uniprot id: A0A0K8J6N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS08140
gene id: 1679721:SD1D_RS08140
uniprot id: A0A0K8J6R8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1679721:SD1D RS11445
gene id: 1679721:SD1D_RS11445
uniprot id: A0A0K8J8A2
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1679721:SD1D RS04600
gene id: 1679721:SD1D_RS04600
uniprot id: A0A0K8J4R5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS11450
gene id: 1679721:SD1D_RS11450
uniprot id: A0A0K8J860
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1679721:SD1D RS01170
gene id: 1679721:SD1D_RS01170
uniprot id: A0A0K8J2B8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1679721:SD1D RS03205
gene id: 1679721:SD1D_RS03205
uniprot id: A0A0K8J4G1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS01230
gene id: 1679721:SD1D_RS01230
uniprot id: A0A0K8J3A7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1679721:SD1D RS01600
gene id: 1679721:SD1D_RS01600
uniprot id: A0A0K8J2Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1679721:SD1D RS05015
gene id: 1679721:SD1D_RS05015
uniprot id: A0A0K8J500
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1679721:SD1D RS01845
gene id: 1679721:SD1D_RS01845
uniprot id: A0A0K8J364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1679721:SD1D RS10965
gene id: 1679721:SD1D_RS10965
uniprot id: A0A0K8J8T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS10155
gene id: 1679721:SD1D_RS10155
uniprot id: A0A0K8J7P8
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS01720
gene id: 1679721:SD1D_RS01720
uniprot id: A0A0K8J338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS07415
gene id: 1679721:SD1D_RS07415
uniprot id: A0A0K8J5T9
names: Similarity
messages: Belongs to the peptidase S14 family.

1679721:SD1D RS11150
gene id: 1679721:SD1D_RS11150
uniprot id: A0A0K8J853
names: Similarity
messages: Belongs to the UPF0236 family.

1679721:SD1D RS02915
gene id: 1679721:SD1D_RS02915
uniprot id: A0A0K8J3S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1679721:SD1D RS00255
gene id: 1679721:SD1D_RS00255
uniprot id: A0A0K8J2C7
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1679721:SD1D RS09895
gene id: 1679721:SD1D_RS09895
uniprot id: A0A0K8J880
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1679721:SD1D RS10025
gene id: 1679721:SD1D_RS10025
uniprot id: A0A0K8J7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1679721:SD1D RS00020
gene id: 1679721:SD1D_RS00020
uniprot id: A0A0K8J2E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1679721:SD1D RS06570
gene id: 1679721:SD1D_RS06570
uniprot id: A0A0K8J5B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1679721:SD1D RS11010
gene id: 1679721:SD1D_RS11010
uniprot id: A0A0K8J7V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1679721:SD1D RS05875
gene id: 1679721:SD1D_RS05875
uniprot id: A0A0K8J5J2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1679721:SD1D RS02585
gene id: 1679721:SD1D_RS02585
uniprot id: A0A0K8J421
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1679721:SD1D RS06085
gene id: 1679721:SD1D_RS06085
uniprot id: A0A0K8J532
names: Similarity
messages: Belongs to the RutC family.

1679721:SD1D RS03015
gene id: 1679721:SD1D_RS03015
uniprot id: A0A0K8J3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS00955
gene id: 1679721:SD1D_RS00955
uniprot id: A0A0K8J365
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS10135
gene id: 1679721:SD1D_RS10135
uniprot id: A0A0K8J7D2
names: Similarity
messages: Belongs to the leucine-binding protein family.

1679721:SD1D RS11675
gene id: 1679721:SD1D_RS11675
uniprot id: A0A0K8J8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1679721:SD1D RS05635
gene id: 1679721:SD1D_RS05635
uniprot id: A0A0K8J5Q2
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

1679721:SD1D RS09970
gene id: 1679721:SD1D_RS09970
uniprot id: A0A0K8J7X4
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS00530
gene id: 1679721:SD1D_RS00530
uniprot id: A0A0K8J2J2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1679721:SD1D RS02690
gene id: 1679721:SD1D_RS02690
uniprot id: A0A0K8J441
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1679721:SD1D RS02015
gene id: 1679721:SD1D_RS02015
uniprot id: A0A0K8J3Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1679721:SD1D RS08175
gene id: 1679721:SD1D_RS08175
uniprot id: A0A0K8J7B1
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS08830
gene id: 1679721:SD1D_RS08830
uniprot id: A0A0K8J790
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS05805
gene id: 1679721:SD1D_RS05805
uniprot id: A0A0K8J5V8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1679721:SD1D RS01470
gene id: 1679721:SD1D_RS01470
uniprot id: A0A0K8J2Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1679721:SD1D RS03590
gene id: 1679721:SD1D_RS03590
uniprot id: A0A0K8J3R4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1679721:SD1D RS10095
gene id: 1679721:SD1D_RS10095
uniprot id: A0A0K8J894
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1679721:SD1D RS10945
gene id: 1679721:SD1D_RS10945
uniprot id: A0A0K8J8Y0
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1679721:SD1D RS11105
gene id: 1679721:SD1D_RS11105
uniprot id: A0A0K8J844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1679721:SD1D RS01660
gene id: 1679721:SD1D_RS01660
uniprot id: A0A0K8J3D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1679721:SD1D RS02560
gene id: 1679721:SD1D_RS02560
uniprot id: A0A0K8J414
names: Similarity
messages: Belongs to the aldose epimerase family.

1679721:SD1D RS10000
gene id: 1679721:SD1D_RS10000
uniprot id: A0A0K8J7M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1679721:SD1D RS00765
gene id: 1679721:SD1D_RS00765
uniprot id: A0A0K8J2M6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1679721:SD1D RS05115
gene id: 1679721:SD1D_RS05115
uniprot id: A0A0K8J5D9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1679721:SD1D RS08240
gene id: 1679721:SD1D_RS08240
uniprot id: A0A0K8J6T8
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1679721:SD1D RS06545
gene id: 1679721:SD1D_RS06545
uniprot id: A0A0K8J5B0
names: Subcellular Location Annotation
messages: Cell membrane

1679721:SD1D RS02830
gene id: 1679721:SD1D_RS02830
uniprot id: A0A0K8J3B1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1679721:SD1D RS08055
gene id: 1679721:SD1D_RS08055
uniprot id: A0A0K8J6Y2
names: Similarity
messages: Belongs to the UPF0473 family.

1679721:SD1D RS00645
gene id: 1679721:SD1D_RS00645
uniprot id: A0A0K8J225
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1679721:SD1D RS08470
gene id: 1679721:SD1D_RS08470
uniprot id: A0A0K8J6L8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1679721:SD1D RS06135
gene id: 1679721:SD1D_RS06135
uniprot id: A0A0K8J542
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

1679721:SD1D RS05815
gene id: 1679721:SD1D_RS05815
uniprot id: A0A0K8J5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1679721:SD1D RS04015
gene id: 1679721:SD1D_RS04015
uniprot id: A0A0K8J3X5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS10385
gene id: 1679721:SD1D_RS10385
uniprot id: A0A0K8J7I4
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS04765
gene id: 1679721:SD1D_RS04765
uniprot id: A0A0K8J4U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1679721:SD1D RS00950
gene id: 1679721:SD1D_RS00950
uniprot id: A0A0K8J2L8
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS11705
gene id: 1679721:SD1D_RS11705
uniprot id: A0A0K8J976
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS10960
gene id: 1679721:SD1D_RS10960
uniprot id: A0A0K8J7V7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1679721:SD1D RS05580
gene id: 1679721:SD1D_RS05580
uniprot id: A0A0K8J5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS11940
gene id: 1679721:SD1D_RS11940
uniprot id: A0A0K8J8U8
names: Similarity
messages: Belongs to the peptidase S11 family.

1679721:SD1D RS07960
gene id: 1679721:SD1D_RS07960
uniprot id: A0A0K8J672
names: Similarity
messages: Belongs to the GSP E family.

1679721:SD1D RS05300
gene id: 1679721:SD1D_RS05300
uniprot id: A0A0K8J4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1679721:SD1D RS08820
gene id: 1679721:SD1D_RS08820
uniprot id: A0A0K8J7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1679721:SD1D RS05000
gene id: 1679721:SD1D_RS05000
uniprot id: A0A0K8J502
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1679721:SD1D RS10105
gene id: 1679721:SD1D_RS10105
uniprot id: A0A0K8J7N7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1679721:SD1D RS10165
gene id: 1679721:SD1D_RS10165
uniprot id: A0A0K8J8D3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1679721:SD1D RS04675
gene id: 1679721:SD1D_RS04675
uniprot id: A0A0K8J4T1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1679721:SD1D RS01710
gene id: 1679721:SD1D_RS01710
uniprot id: A0A0K8J3K1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1679721:SD1D RS10170
gene id: 1679721:SD1D_RS10170
uniprot id: A0A0K8J8A9
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1679721:SD1D RS11775
gene id: 1679721:SD1D_RS11775
uniprot id: A0A0K8J8B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1679721:SD1D RS01425
gene id: 1679721:SD1D_RS01425
uniprot id: A0A0K8J2U5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1679721:SD1D RS01950
gene id: 1679721:SD1D_RS01950
uniprot id: A0A0K8J382
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS03965
gene id: 1679721:SD1D_RS03965
uniprot id: A0A0K8J3W6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS03595
gene id: 1679721:SD1D_RS03595
uniprot id: A0A0K8J469
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1679721:SD1D RS10985
gene id: 1679721:SD1D_RS10985
uniprot id: A0A0K8J7V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1679721:SD1D RS00310
gene id: 1679721:SD1D_RS00310
uniprot id: A0A0K8J1U3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1679721:SD1D RS09625
gene id: 1679721:SD1D_RS09625
uniprot id: A0A0K8J744
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1679721:SD1D RS11370
gene id: 1679721:SD1D_RS11370
uniprot id: A0A0K8J888
names: Similarity
messages: Belongs to the SfsA family.

1679721:SD1D RS03425
gene id: 1679721:SD1D_RS03425
uniprot id: A0A0K8J4K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS08190
gene id: 1679721:SD1D_RS08190
uniprot id: A0A0K8J6S8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1679721:SD1D RS04390
gene id: 1679721:SD1D_RS04390
uniprot id: A0A0K8J446
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1679721:SD1D RS12320
gene id: 1679721:SD1D_RS12320
uniprot id: A0A0K8J6X1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS00025
gene id: 1679721:SD1D_RS00025
uniprot id: A0A0K8J294
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1679721:SD1D RS12015
gene id: 1679721:SD1D_RS12015
uniprot id: A0A0K8J9J6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS06390
gene id: 1679721:SD1D_RS06390
uniprot id: A0A0K8J5T5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1679721:SD1D RS01175
gene id: 1679721:SD1D_RS01175
uniprot id: A0A0K8J2Q5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1679721:SD1D RS02245
gene id: 1679721:SD1D_RS02245
uniprot id: A0A0K8J3R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1679721:SD1D RS03115
gene id: 1679721:SD1D_RS03115
uniprot id: A0A0K8J3X1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1679721:SD1D RS00215
gene id: 1679721:SD1D_RS00215
uniprot id: A0A0K8J281
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS02645
gene id: 1679721:SD1D_RS02645
uniprot id: A0A0K8J3Y9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1679721:SD1D RS07910
gene id: 1679721:SD1D_RS07910
uniprot id: A0A0K8J635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1679721:SD1D RS07660
gene id: 1679721:SD1D_RS07660
uniprot id: A0A0K8J6U3
names: Similarity
messages: Belongs to the peptidase S14 family.

1679721:SD1D RS11045
gene id: 1679721:SD1D_RS11045
uniprot id: A0A0K8J8Z6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1679721:SD1D RS05585
gene id: 1679721:SD1D_RS05585
uniprot id: A0A0K8J5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1679721:SD1D RS08920
gene id: 1679721:SD1D_RS08920
uniprot id: A0A0K8J730
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1679721:SD1D RS10600
gene id: 1679721:SD1D_RS10600
uniprot id: A0A0K8J8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1679721:SD1D RS02230
gene id: 1679721:SD1D_RS02230
uniprot id: A0A0K8J2Y0
names: Similarity
messages: Belongs to the peptidase S8 family.

1679721:SD1D RS00170
gene id: 1679721:SD1D_RS00170
uniprot id: A0A0K8J2Q4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS08500
gene id: 1679721:SD1D_RS08500
uniprot id: A0A0K8J6M1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1679721:SD1D RS09225
gene id: 1679721:SD1D_RS09225
uniprot id: A0A0K8J7G1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1679721:SD1D RS04205
gene id: 1679721:SD1D_RS04205
uniprot id: A0A0K8J4W5
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1679721:SD1D RS09695
gene id: 1679721:SD1D_RS09695
uniprot id: A0A0K8J7I0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1679721:SD1D RS01750
gene id: 1679721:SD1D_RS01750
uniprot id: A0A0K8J2P2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1679721:SD1D RS04660
gene id: 1679721:SD1D_RS04660
uniprot id: A0A0K8J556
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1679721:SD1D RS00885
gene id: 1679721:SD1D_RS00885
uniprot id: A0A0K8J2P3
names: Similarity
messages: Belongs to the peptidase S8 family.

1679721:SD1D RS10090
gene id: 1679721:SD1D_RS10090
uniprot id: A0A0K8J8B7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1679721:SD1D RS02385
gene id: 1679721:SD1D_RS02385
uniprot id: A0A0K8J3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS04505
gene id: 1679721:SD1D_RS04505
uniprot id: A0A0K8J540
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1679721:SD1D RS08485
gene id: 1679721:SD1D_RS08485
uniprot id: A0A0K8J7D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1679721:SD1D RS05575
gene id: 1679721:SD1D_RS05575
uniprot id: A0A0K8J5D3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1679721:SD1D RS08880
gene id: 1679721:SD1D_RS08880
uniprot id: A0A0K8J798
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

1679721:SD1D RS03460
gene id: 1679721:SD1D_RS03460
uniprot id: A0A0K8J436
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS05355
gene id: 1679721:SD1D_RS05355
uniprot id: A0A0K8J5K4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1679721:SD1D RS06330
gene id: 1679721:SD1D_RS06330
uniprot id: A0A0K8J5S6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1679721:SD1D RS11225
gene id: 1679721:SD1D_RS11225
uniprot id: A0A0K8J866
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1679721:SD1D RS10360
gene id: 1679721:SD1D_RS10360
uniprot id: A0A0K8J7H9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1679721:SD1D RS04845
gene id: 1679721:SD1D_RS04845
uniprot id: A0A0K8J4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS09795
gene id: 1679721:SD1D_RS09795
uniprot id: A0A0K8J7S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1679721:SD1D RS10610
gene id: 1679721:SD1D_RS10610
uniprot id: A0A0K8J7Y7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1679721:SD1D RS10260
gene id: 1679721:SD1D_RS10260
uniprot id: A0A0K8J8F1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1679721:SD1D RS06875
gene id: 1679721:SD1D_RS06875
uniprot id: A0A0K8J5H7
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS02605
gene id: 1679721:SD1D_RS02605
uniprot id: A0A0K8J3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1679721:SD1D RS04280
gene id: 1679721:SD1D_RS04280
uniprot id: A0A0K8J4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1679721:SD1D RS05480
gene id: 1679721:SD1D_RS05480
uniprot id: A0A0K8J5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1679721:SD1D RS03325
gene id: 1679721:SD1D_RS03325
uniprot id: A0A0K8J4I4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1679721:SD1D RS04935
gene id: 1679721:SD1D_RS04935
uniprot id: A0A0K8J5A2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1679721:SD1D RS04640
gene id: 1679721:SD1D_RS04640
uniprot id: A0A0K8J4R7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1679721:SD1D RS01065
gene id: 1679721:SD1D_RS01065
uniprot id: A0A0K8J299
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1679721:SD1D RS05910
gene id: 1679721:SD1D_RS05910
uniprot id: A0A0K8J5J8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1679721:SD1D RS04190
gene id: 1679721:SD1D_RS04190
uniprot id: A0A0K8J410
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS05405
gene id: 1679721:SD1D_RS05405
uniprot id: A0A0K8J5L2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1679721:SD1D RS05625
gene id: 1679721:SD1D_RS05625
uniprot id: A0A0K8J5E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1679721:SD1D RS10525
gene id: 1679721:SD1D_RS10525
uniprot id: A0A0K8J8P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1679721:SD1D RS02825
gene id: 1679721:SD1D_RS02825
uniprot id: A0A0K8J3P4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1679721:SD1D RS03370
gene id: 1679721:SD1D_RS03370
uniprot id: A0A0K8J430
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS08555
gene id: 1679721:SD1D_RS08555
uniprot id: A0A0K8J7H2
names: Subcellular Location Annotation
messages: Cell membrane

1679721:SD1D RS07480
gene id: 1679721:SD1D_RS07480
uniprot id: A0A0K8J6L4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1679721:SD1D RS02370
gene id: 1679721:SD1D_RS02370
uniprot id: A0A0K8J3F7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS07595
gene id: 1679721:SD1D_RS07595
uniprot id: A0A0K8J6N7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1679721:SD1D RS11735
gene id: 1679721:SD1D_RS11735
uniprot id: A0A0K8J9D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1679721:SD1D RS06295
gene id: 1679721:SD1D_RS06295
uniprot id: A0A0K8J650
names: Subcellular Location Annotation
messages: Cytoplasm

1679721:SD1D RS02875
gene id: 1679721:SD1D_RS02875
uniprot id: A0A0K8J443
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1679721:SD1D RS06420
gene id: 1679721:SD1D_RS06420
uniprot id: A0A0K8J669
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS09325
gene id: 1679721:SD1D_RS09325
uniprot id: A0A0K8J7I1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1679721:SD1D RS02470
gene id: 1679721:SD1D_RS02470
uniprot id: A0A0K8J3H3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS04825
gene id: 1679721:SD1D_RS04825
uniprot id: A0A0K8J4W4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1679721:SD1D RS10700
gene id: 1679721:SD1D_RS10700
uniprot id: A0A0K8J7T7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1679721:SD1D RS06160
gene id: 1679721:SD1D_RS06160
uniprot id: A0A0K8J554
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpsD/CapB family.
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1679721:SD1D RS03660
gene id: 1679721:SD1D_RS03660
uniprot id: A0A0K8J468
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1679721:SD1D RS05260
gene id: 1679721:SD1D_RS05260
uniprot id: A0A0K8J5I1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1679721:SD1D RS04100
gene id: 1679721:SD1D_RS04100
uniprot id: A0A0K8J4V9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1679721:SD1D RS08085
gene id: 1679721:SD1D_RS08085
uniprot id: A0A0K8J6Q9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1679721:SD1D RS03160
gene id: 1679721:SD1D_RS03160
uniprot id: A0A0K8J4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS03585
gene id: 1679721:SD1D_RS03585
uniprot id: A0A0K8J457
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1679721:SD1D RS10570
gene id: 1679721:SD1D_RS10570
uniprot id: A0A0K8J8N6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS07545
gene id: 1679721:SD1D_RS07545
uniprot id: A0A0K8J6K3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1679721:SD1D RS09655
gene id: 1679721:SD1D_RS09655
uniprot id: A0A0K8J836
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1679721:SD1D RS11785
gene id: 1679721:SD1D_RS11785
uniprot id: A0A0K8J9G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS01630
gene id: 1679721:SD1D_RS01630
uniprot id: A0A0K8J3J1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1679721:SD1D RS11595
gene id: 1679721:SD1D_RS11595
uniprot id: A0A0K8J8D5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1679721:SD1D RS05310
gene id: 1679721:SD1D_RS05310
uniprot id: A0A0K8J5J6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1679721:SD1D RS01575
gene id: 1679721:SD1D_RS01575
uniprot id: A0A0K8J2X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1679721:SD1D RS08790
gene id: 1679721:SD1D_RS08790
uniprot id: A0A0K8J6S2
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS07260
gene id: 1679721:SD1D_RS07260
uniprot id: A0A0K8J698
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1679721:SD1D RS06860
gene id: 1679721:SD1D_RS06860
uniprot id: A0A0K8J6F9
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1679721:SD1D RS10125
gene id: 1679721:SD1D_RS10125
uniprot id: A0A0K8J800
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS01415
gene id: 1679721:SD1D_RS01415
uniprot id: A0A0K8J2X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1679721:SD1D RS11435
gene id: 1679721:SD1D_RS11435
uniprot id: A0A0K8J975
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1679721:SD1D RS04670
gene id: 1679721:SD1D_RS04670
uniprot id: A0A0K8J495
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1679721:SD1D RS05150
gene id: 1679721:SD1D_RS05150
uniprot id: A0A0K8J4I8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1679721:SD1D RS01655
gene id: 1679721:SD1D_RS01655
uniprot id: A0A0K8J3J5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1679721:SD1D RS03340
gene id: 1679721:SD1D_RS03340
uniprot id: A0A0K8J3M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS00330
gene id: 1679721:SD1D_RS00330
uniprot id: A0A0K8J1U8
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

1679721:SD1D RS01735
gene id: 1679721:SD1D_RS01735
uniprot id: A0A0K8J3K7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS01590
gene id: 1679721:SD1D_RS01590
uniprot id: A0A0K8J312
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1679721:SD1D RS02405
gene id: 1679721:SD1D_RS02405
uniprot id: A0A0K8J3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1679721:SD1D RS08800
gene id: 1679721:SD1D_RS08800
uniprot id: A0A0K8J7J7
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1679721:SD1D RS11605
gene id: 1679721:SD1D_RS11605
uniprot id: A0A0K8J967
names: Similarity
messages: Belongs to the CapA family.

1679721:SD1D RS10005
gene id: 1679721:SD1D_RS10005
uniprot id: A0A0K8J7B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1679721:SD1D RS09580
gene id: 1679721:SD1D_RS09580
uniprot id: A0A0K8J820
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1679721:SD1D RS09035
gene id: 1679721:SD1D_RS09035
uniprot id: A0A0K8J7P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1679721:SD1D RS02310
gene id: 1679721:SD1D_RS02310
uniprot id: A0A0K8J3V6
names: Subcellular Location Annotation
messages: Cytoplasm

1679721:SD1D RS01790
gene id: 1679721:SD1D_RS01790
uniprot id: A0A0K8J3F6
names: Similarity
messages: Belongs to the peptidase S41A family.

1679721:SD1D RS10860
gene id: 1679721:SD1D_RS10860
uniprot id: A0A0K8J7V1
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1679721:SD1D RS07280
gene id: 1679721:SD1D_RS07280
uniprot id: A0A0K8J6H9
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1679721:SD1D RS00635
gene id: 1679721:SD1D_RS00635
uniprot id: A0A0K8J2V9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1679721:SD1D RS06835
gene id: 1679721:SD1D_RS06835
uniprot id: A0A0K8J6F6
names: Similarity
messages: Belongs to the hemerythrin family.

1679721:SD1D RS01445
gene id: 1679721:SD1D_RS01445
uniprot id: A0A0K8J2Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1679721:SD1D RS08960
gene id: 1679721:SD1D_RS08960
uniprot id: A0A0K8J7M7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1679721:SD1D RS10310
gene id: 1679721:SD1D_RS10310
uniprot id: A0A0K8J7G8
names: Caution
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS05010
gene id: 1679721:SD1D_RS05010
uniprot id: A0A0K8J5B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS09045
gene id: 1679721:SD1D_RS09045
uniprot id: A0A0K8J7C7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1679721:SD1D RS06065
gene id: 1679721:SD1D_RS06065
uniprot id: A0A0K8J5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS01905
gene id: 1679721:SD1D_RS01905
uniprot id: A0A0K8J2S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1679721:SD1D RS01730
gene id: 1679721:SD1D_RS01730
uniprot id: A0A0K8J310
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS09195
gene id: 1679721:SD1D_RS09195
uniprot id: A0A0K8J7S6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1679721:SD1D RS06250
gene id: 1679721:SD1D_RS06250
uniprot id: A0A0K8J617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1679721:SD1D RS03495
gene id: 1679721:SD1D_RS03495
uniprot id: A0A0K8J452
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS09040
gene id: 1679721:SD1D_RS09040
uniprot id: A0A0K8J7Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1679721:SD1D RS05555
gene id: 1679721:SD1D_RS05555
uniprot id: A0A0K8J5Q4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1679721:SD1D RS09830
gene id: 1679721:SD1D_RS09830
uniprot id: A0A0K8J778
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS00010
gene id: 1679721:SD1D_RS00010
uniprot id: A0A0K8J249
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1679721:SD1D RS10865
gene id: 1679721:SD1D_RS10865
uniprot id: A0A0K8J8R7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1679721:SD1D RS05200
gene id: 1679721:SD1D_RS05200
uniprot id: A0A0K8J4K0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1679721:SD1D RS08725
gene id: 1679721:SD1D_RS08725
uniprot id: A0A0K8J7K7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS05680
gene id: 1679721:SD1D_RS05680
uniprot id: A0A0K8J5T4
names: Similarity
messages: Belongs to the UPF0758 family.

1679721:SD1D RS09710
gene id: 1679721:SD1D_RS09710
uniprot id: A0A0K8J822
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1679721:SD1D RS01920
gene id: 1679721:SD1D_RS01920
uniprot id: A0A0K8J3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1679721:SD1D RS04360
gene id: 1679721:SD1D_RS04360
uniprot id: A0A0K8J4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1679721:SD1D RS06350
gene id: 1679721:SD1D_RS06350
uniprot id: A0A0K8J5T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1679721:SD1D RS05765
gene id: 1679721:SD1D_RS05765
uniprot id: A0A0K8J5G6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS04060
gene id: 1679721:SD1D_RS04060
uniprot id: A0A0K8J4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS01240
gene id: 1679721:SD1D_RS01240
uniprot id: A0A0K8J2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1679721:SD1D RS10330
gene id: 1679721:SD1D_RS10330
uniprot id: A0A0K8J7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1679721:SD1D RS04440
gene id: 1679721:SD1D_RS04440
uniprot id: A0A0K8J4P1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS09085
gene id: 1679721:SD1D_RS09085
uniprot id: A0A0K8J750
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1679721:SD1D RS06190
gene id: 1679721:SD1D_RS06190
uniprot id: A0A0K8J5P8
names: Similarity
messages: Belongs to the YjdM family.

1679721:SD1D RS02805
gene id: 1679721:SD1D_RS02805
uniprot id: A0A0K8J3A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS04810
gene id: 1679721:SD1D_RS04810
uniprot id: A0A0K8J584
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS04815
gene id: 1679721:SD1D_RS04815
uniprot id: A0A0K8J4U9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1679721:SD1D RS01810
gene id: 1679721:SD1D_RS01810
uniprot id: A0A0K8J3M2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1679721:SD1D RS10595
gene id: 1679721:SD1D_RS10595
uniprot id: A0A0K8J8P1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1679721:SD1D RS05235
gene id: 1679721:SD1D_RS05235
uniprot id: A0A0K8J5H8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1679721:SD1D RS05525
gene id: 1679721:SD1D_RS05525
uniprot id: A0A0K8J5C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

1679721:SD1D RS04900
gene id: 1679721:SD1D_RS04900
uniprot id: A0A0K8J4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1679721:SD1D RS01650
gene id: 1679721:SD1D_RS01650
uniprot id: A0A0K8J2Z2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1679721:SD1D RS11765
gene id: 1679721:SD1D_RS11765
uniprot id: A0A0K8J8R4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS00415
gene id: 1679721:SD1D_RS00415
uniprot id: A0A0K8J2D7
names: Similarity
messages: Belongs to the serpin family.

1679721:SD1D RS01645
gene id: 1679721:SD1D_RS01645
uniprot id: A0A0K8J2M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1679721:SD1D RS04685
gene id: 1679721:SD1D_RS04685
uniprot id: A0A0K8J562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1679721:SD1D RS04030
gene id: 1679721:SD1D_RS04030
uniprot id: A0A0K8J4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1679721:SD1D RS08720
gene id: 1679721:SD1D_RS08720
uniprot id: A0A0K8J6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1679721:SD1D RS05390
gene id: 1679721:SD1D_RS05390
uniprot id: A0A0K8J578
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1679721:SD1D RS05640
gene id: 1679721:SD1D_RS05640
uniprot id: A0A0K8J5E3
names: Similarity
messages: Belongs to the peptidase C40 family.

1679721:SD1D RS02360
gene id: 1679721:SD1D_RS02360
uniprot id: A0A0K8J3W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1679721:SD1D RS10455
gene id: 1679721:SD1D_RS10455
uniprot id: A0A0K8J868
names: Similarity
messages: Belongs to the peptidase S11 family.

1679721:SD1D RS01035
gene id: 1679721:SD1D_RS01035
uniprot id: A0A0K8J2S1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1679721:SD1D RS06415
gene id: 1679721:SD1D_RS06415
uniprot id: A0A0K8J5U3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1679721:SD1D RS08310
gene id: 1679721:SD1D_RS08310
uniprot id: A0A0K8J715
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1679721:SD1D RS08305
gene id: 1679721:SD1D_RS08305
uniprot id: A0A0K8J7A7
names: Similarity
messages: Belongs to the asp23 family.

1679721:SD1D RS08810
gene id: 1679721:SD1D_RS08810
uniprot id: A0A0K8J712
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS04775
gene id: 1679721:SD1D_RS04775
uniprot id: A0A0K8J4V7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

1679721:SD1D RS08060
gene id: 1679721:SD1D_RS08060
uniprot id: A0A0K8J6Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1679721:SD1D RS00780
gene id: 1679721:SD1D_RS00780
uniprot id: A0A0K8J334
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1679721:SD1D RS08585
gene id: 1679721:SD1D_RS08585
uniprot id: A0A0K8J7F5
names: Similarity
messages: Belongs to the TlyA family.

1679721:SD1D RS04735
gene id: 1679721:SD1D_RS04735
uniprot id: A0A0K8J570
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1679721:SD1D RS10615
gene id: 1679721:SD1D_RS10615
uniprot id: A0A0K8J7Q1
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1679721:SD1D RS08595
gene id: 1679721:SD1D_RS08595
uniprot id: A0A0K8J6Y4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1679721:SD1D RS05165
gene id: 1679721:SD1D_RS05165
uniprot id: A0A0K8J5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1679721:SD1D RS03165
gene id: 1679721:SD1D_RS03165
uniprot id: A0A0K8J3Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1679721:SD1D RS10590
gene id: 1679721:SD1D_RS10590
uniprot id: A0A0K8J7P7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1679721:SD1D RS12060
gene id: 1679721:SD1D_RS12060
uniprot id: A0A0K8J9E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1679721:SD1D RS07105
gene id: 1679721:SD1D_RS07105
uniprot id: A0A0K8J5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1679721:SD1D RS01775
gene id: 1679721:SD1D_RS01775
uniprot id: A0A0K8J2P6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS08795
gene id: 1679721:SD1D_RS08795
uniprot id: A0A0K8J7L5
names: Similarity
messages: Belongs to the peptidase C40 family.

1679721:SD1D RS04040
gene id: 1679721:SD1D_RS04040
uniprot id: A0A0K8J3Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1679721:SD1D RS00980
gene id: 1679721:SD1D_RS00980
uniprot id: A0A0K8J323
names: Similarity
messages: Belongs to the HypE family.

1679721:SD1D RS09305
gene id: 1679721:SD1D_RS09305
uniprot id: A0A0K8J783
names: Similarity
messages: Belongs to the EamA transporter family.

1679721:SD1D RS03785
gene id: 1679721:SD1D_RS03785
uniprot id: A0A0K8J3T7
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS11615
gene id: 1679721:SD1D_RS11615
uniprot id: A0A0K8J8N7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1679721:SD1D RS02850
gene id: 1679721:SD1D_RS02850
uniprot id: A0A0K8J3Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1679721:SD1D RS03225
gene id: 1679721:SD1D_RS03225
uniprot id: A0A0K8J3K2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS04075
gene id: 1679721:SD1D_RS04075
uniprot id: A0A0K8J4V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS09755
gene id: 1679721:SD1D_RS09755
uniprot id: A0A0K8J770
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS05620
gene id: 1679721:SD1D_RS05620
uniprot id: A0A0K8J4V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1679721:SD1D RS09690
gene id: 1679721:SD1D_RS09690
uniprot id: A0A0K8J7R2
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1679721:SD1D RS11955
gene id: 1679721:SD1D_RS11955
uniprot id: A0A0K8J9D4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS11155
gene id: 1679721:SD1D_RS11155
uniprot id: A0A0K8J7Y2
names: Similarity
messages: Belongs to the plasmid mobilization pre family.

1679721:SD1D RS03815
gene id: 1679721:SD1D_RS03815
uniprot id: A0A0K8J4A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

1679721:SD1D RS01435
gene id: 1679721:SD1D_RS01435
uniprot id: A0A0K8J3A2
names: Similarity
messages: Belongs to the peptidase S8 family.

1679721:SD1D RS10515
gene id: 1679721:SD1D_RS10515
uniprot id: A0A0K8J7N4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS06255
gene id: 1679721:SD1D_RS06255
uniprot id: A0A0K8J5R0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1679721:SD1D RS03030
gene id: 1679721:SD1D_RS03030
uniprot id: A0A0K8J4D2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS03485
gene id: 1679721:SD1D_RS03485
uniprot id: A0A0K8J439
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1679721:SD1D RS08125
gene id: 1679721:SD1D_RS08125
uniprot id: A0A0K8J751
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1679721:SD1D RS03080
gene id: 1679721:SD1D_RS03080
uniprot id: A0A0K8J4D8
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1679721:SD1D RS04285
gene id: 1679721:SD1D_RS04285
uniprot id: A0A0K8J4L4
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1679721:SD1D RS06400
gene id: 1679721:SD1D_RS06400
uniprot id: A0A0K8J643
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1679721:SD1D RS00190
gene id: 1679721:SD1D_RS00190
uniprot id: A0A0K8J276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1679721:SD1D RS12055
gene id: 1679721:SD1D_RS12055
uniprot id: A0A0K8J8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1679721:SD1D RS01685
gene id: 1679721:SD1D_RS01685
uniprot id: A0A0K8J3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1679721:SD1D RS02795
gene id: 1679721:SD1D_RS02795
uniprot id: A0A0K8J423
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1679721:SD1D RS09990
gene id: 1679721:SD1D_RS09990
uniprot id: A0A0K8J878
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS00160
gene id: 1679721:SD1D_RS00160
uniprot id: A0A0K8J1R0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1679721:SD1D RS09825
gene id: 1679721:SD1D_RS09825
uniprot id: A0A0K8J7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1679721:SD1D RS03655
gene id: 1679721:SD1D_RS03655
uniprot id: A0A0K8J4J7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1679721:SD1D RS01075
gene id: 1679721:SD1D_RS01075
uniprot id: A0A0K8J383
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1679721:SD1D RS05550
gene id: 1679721:SD1D_RS05550
uniprot id: A0A0K8J5D1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1679721:SD1D RS03465
gene id: 1679721:SD1D_RS03465
uniprot id: A0A0K8J3P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1679721:SD1D RS01070
gene id: 1679721:SD1D_RS01070
uniprot id: A0A0K8J2N8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1679721:SD1D RS10825
gene id: 1679721:SD1D_RS10825
uniprot id: A0A0K8J8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1679721:SD1D RS00610
gene id: 1679721:SD1D_RS00610
uniprot id: A0A0K8J2V5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1679721:SD1D RS09355
gene id: 1679721:SD1D_RS09355
uniprot id: A0A0K8J7I6
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS05490
gene id: 1679721:SD1D_RS05490
uniprot id: A0A0K8J5B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1679721:SD1D RS01665
gene id: 1679721:SD1D_RS01665
uniprot id: A0A0K8J328
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1679721:SD1D RS08785
gene id: 1679721:SD1D_RS08785
uniprot id: A0A0K8J708
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS06500
gene id: 1679721:SD1D_RS06500
uniprot id: A0A0K8J5W0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1679721:SD1D RS00005
gene id: 1679721:SD1D_RS00005
uniprot id: A0A0K8J1N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1679721:SD1D RS00880
gene id: 1679721:SD1D_RS00880
uniprot id: A0A0K8J305
names: Similarity
messages: Belongs to the peptidase S8 family.

1679721:SD1D RS10440
gene id: 1679721:SD1D_RS10440
uniprot id: A0A0K8J7J5
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1679721:SD1D RS10475
gene id: 1679721:SD1D_RS10475
uniprot id: A0A0K8J8N5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1679721:SD1D RS02120
gene id: 1679721:SD1D_RS02120
uniprot id: A0A0K8J3P1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS00260
gene id: 1679721:SD1D_RS00260
uniprot id: A0A0K8J1T2
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS09790
gene id: 1679721:SD1D_RS09790
uniprot id: A0A0K8J838
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1679721:SD1D RS11625
gene id: 1679721:SD1D_RS11625
uniprot id: A0A0K8J891
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1679721:SD1D RS01155
gene id: 1679721:SD1D_RS01155
uniprot id: A0A0K8J2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1679721:SD1D RS04165
gene id: 1679721:SD1D_RS04165
uniprot id: A0A0K8J405
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1679721:SD1D RS07710
gene id: 1679721:SD1D_RS07710
uniprot id: A0A0K8J6V0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1679721:SD1D RS10695
gene id: 1679721:SD1D_RS10695
uniprot id: A0A0K8J7Z2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1679721:SD1D RS11700
gene id: 1679721:SD1D_RS11700
uniprot id: A0A0K8J8A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1679721:SD1D RS08775
gene id: 1679721:SD1D_RS08775
uniprot id: A0A0K8J7J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1679721:SD1D RS02305
gene id: 1679721:SD1D_RS02305
uniprot id: A0A0K8J3F4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1679721:SD1D RS06355
gene id: 1679721:SD1D_RS06355
uniprot id: A0A0K8J588
names: Similarity
messages: Belongs to the UPF0251 family.

1679721:SD1D RS00485
gene id: 1679721:SD1D_RS00485
uniprot id: A0A0K8J205
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1679721:SD1D RS05955
gene id: 1679721:SD1D_RS05955
uniprot id: A0A0K8J5W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1679721:SD1D RS01345
gene id: 1679721:SD1D_RS01345
uniprot id: A0A0K8J2E8
names: Similarity
messages: Belongs to the thioredoxin family.

1679721:SD1D RS10815
gene id: 1679721:SD1D_RS10815
uniprot id: A0A0K8J8Q9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1679721:SD1D RS01015
gene id: 1679721:SD1D_RS01015
uniprot id: A0A0K8J291
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1679721:SD1D RS05570
gene id: 1679721:SD1D_RS05570
uniprot id: A0A0K8J4U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1679721:SD1D RS02730
gene id: 1679721:SD1D_RS02730
uniprot id: A0A0K8J389
names: Similarity
messages: Belongs to the EamA transporter family.

1679721:SD1D RS09645
gene id: 1679721:SD1D_RS09645
uniprot id: A0A0K8J7H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS08340
gene id: 1679721:SD1D_RS08340
uniprot id: A0A0K8J6U9
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS05285
gene id: 1679721:SD1D_RS05285
uniprot id: A0A0K8J5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1679721:SD1D RS01565
gene id: 1679721:SD1D_RS01565
uniprot id: A0A0K8J307
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1679721:SD1D RS00900
gene id: 1679721:SD1D_RS00900
uniprot id: A0A0K8J356
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1679721:SD1D RS01225
gene id: 1679721:SD1D_RS01225
uniprot id: A0A0K8J2R4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1679721:SD1D RS10955
gene id: 1679721:SD1D_RS10955
uniprot id: A0A0K8J816
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1679721:SD1D RS08515
gene id: 1679721:SD1D_RS08515
uniprot id: A0A0K8J740
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1679721:SD1D RS02925
gene id: 1679721:SD1D_RS02925
uniprot id: A0A0K8J478
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS01785
gene id: 1679721:SD1D_RS01785
uniprot id: A0A0K8J3L6
names: Similarity
messages: Belongs to the CdaR family.

1679721:SD1D RS04410
gene id: 1679721:SD1D_RS04410
uniprot id: A0A0K8J4N8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1679721:SD1D RS02425
gene id: 1679721:SD1D_RS02425
uniprot id: A0A0K8J324
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1679721:SD1D RS08230
gene id: 1679721:SD1D_RS08230
uniprot id: A0A0K8J795
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1679721:SD1D RS11470
gene id: 1679721:SD1D_RS11470
uniprot id: A0A0K8J8B0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1679721:SD1D RS06035
gene id: 1679721:SD1D_RS06035
uniprot id: A0A0K8J5L7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1679721:SD1D RS09675
gene id: 1679721:SD1D_RS09675
uniprot id: A0A0K8J754
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1679721:SD1D RS04070
gene id: 1679721:SD1D_RS04070
uniprot id: A0A0K8J4E7
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS02095
gene id: 1679721:SD1D_RS02095
uniprot id: A0A0K8J3N5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1679721:SD1D RS01460
gene id: 1679721:SD1D_RS01460
uniprot id: A0A0K8J3E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1679721:SD1D RS03980
gene id: 1679721:SD1D_RS03980
uniprot id: A0A0K8J4S5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1679721:SD1D RS04750
gene id: 1679721:SD1D_RS04750
uniprot id: A0A0K8J4V0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1679721:SD1D RS00700
gene id: 1679721:SD1D_RS00700
uniprot id: A0A0K8J235
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1679721:SD1D RS04840
gene id: 1679721:SD1D_RS04840
uniprot id: A0A0K8J4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS03850
gene id: 1679721:SD1D_RS03850
uniprot id: A0A0K8J4Q4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS11970
gene id: 1679721:SD1D_RS11970
uniprot id: A0A0K8J8J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS11505
gene id: 1679721:SD1D_RS11505
uniprot id: A0A0K8J953
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS05685
gene id: 1679721:SD1D_RS05685
uniprot id: A0A0K8J5R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS04185
gene id: 1679721:SD1D_RS04185
uniprot id: A0A0K8J4J2
names: Subcellular Location Annotation
messages: Cytoplasm

1679721:SD1D RS01925
gene id: 1679721:SD1D_RS01925
uniprot id: A0A0K8J378
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1679721:SD1D RS04425
gene id: 1679721:SD1D_RS04425
uniprot id: A0A0K8J4L7
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS04500
gene id: 1679721:SD1D_RS04500
uniprot id: A0A0K8J4N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1679721:SD1D RS11585
gene id: 1679721:SD1D_RS11585
uniprot id: A0A0K8J983
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1679721:SD1D RS08715
gene id: 1679721:SD1D_RS08715
uniprot id: A0A0K8J773
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1679721:SD1D RS05905
gene id: 1679721:SD1D_RS05905
uniprot id: A0A0K8J5V2
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS01595
gene id: 1679721:SD1D_RS01595
uniprot id: A0A0K8J2L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1679721:SD1D RS04930
gene id: 1679721:SD1D_RS04930
uniprot id: A0A0K8J5B3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1679721:SD1D RS06105
gene id: 1679721:SD1D_RS06105
uniprot id: A0A0K8J5M8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1679721:SD1D RS00945
gene id: 1679721:SD1D_RS00945
uniprot id: A0A0K8J277
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1679721:SD1D RS04320
gene id: 1679721:SD1D_RS04320
uniprot id: A0A0K8J4J6
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1679721:SD1D RS00935
gene id: 1679721:SD1D_RS00935
uniprot id: A0A0K8J314
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1679721:SD1D RS09210
gene id: 1679721:SD1D_RS09210
uniprot id: A0A0K8J6Y7
names: Similarity
messages: Belongs to the fabD family.

1679721:SD1D RS04580
gene id: 1679721:SD1D_RS04580
uniprot id: A0A0K8J552
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1679721:SD1D RS01640
gene id: 1679721:SD1D_RS01640
uniprot id: A0A0K8J322
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1679721:SD1D RS08130
gene id: 1679721:SD1D_RS08130
uniprot id: A0A0K8J6Z1
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1679721:SD1D RS03480
gene id: 1679721:SD1D_RS03480
uniprot id: A0A0K8J4G7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1679721:SD1D RS06100
gene id: 1679721:SD1D_RS06100
uniprot id: A0A0K8J5Z0
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1679721:SD1D RS03320
gene id: 1679721:SD1D_RS03320
uniprot id: A0A0K8J422
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1679721:SD1D RS02680
gene id: 1679721:SD1D_RS02680
uniprot id: A0A0K8J380
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS03665
gene id: 1679721:SD1D_RS03665
uniprot id: A0A0K8J3S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1679721:SD1D RS08600
gene id: 1679721:SD1D_RS08600
uniprot id: A0A0K8J6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1679721:SD1D RS03765
gene id: 1679721:SD1D_RS03765
uniprot id: A0A0K8J498
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1679721:SD1D RS11135
gene id: 1679721:SD1D_RS11135
uniprot id: A0A0K8J8W7
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS09025
gene id: 1679721:SD1D_RS09025
uniprot id: A0A0K8J742
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1679721:SD1D RS09320
gene id: 1679721:SD1D_RS09320
uniprot id: A0A0K8J7W2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS11580
gene id: 1679721:SD1D_RS11580
uniprot id: A0A0K8J963
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1679721:SD1D RS06675
gene id: 1679721:SD1D_RS06675
uniprot id: A0A0K8J5Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1679721:SD1D RS09670
gene id: 1679721:SD1D_RS09670
uniprot id: A0A0K8J7H5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1679721:SD1D RS05495
gene id: 1679721:SD1D_RS05495
uniprot id: A0A0K8J4S7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1679721:SD1D RS00580
gene id: 1679721:SD1D_RS00580
uniprot id: A0A0K8J300
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1679721:SD1D RS03435
gene id: 1679721:SD1D_RS03435
uniprot id: A0A0K8J431
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1679721:SD1D RS03440
gene id: 1679721:SD1D_RS03440
uniprot id: A0A0K8J3N8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1679721:SD1D RS05560
gene id: 1679721:SD1D_RS05560
uniprot id: A0A0K8J5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1679721:SD1D RS04795
gene id: 1679721:SD1D_RS04795
uniprot id: A0A0K8J4B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1679721:SD1D RS05410
gene id: 1679721:SD1D_RS05410
uniprot id: A0A0K8J5J9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1679721:SD1D RS04025
gene id: 1679721:SD1D_RS04025
uniprot id: A0A0K8J4U3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1679721:SD1D RS04400
gene id: 1679721:SD1D_RS04400
uniprot id: A0A0K8J518
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS00030
gene id: 1679721:SD1D_RS00030
uniprot id: A0A0K8J1P4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1679721:SD1D RS05655
gene id: 1679721:SD1D_RS05655
uniprot id: A0A0K8J5S8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1679721:SD1D RS06880
gene id: 1679721:SD1D_RS06880
uniprot id: A0A0K8J637
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS08105
gene id: 1679721:SD1D_RS08105
uniprot id: A0A0K8J6Y8
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1679721:SD1D RS02390
gene id: 1679721:SD1D_RS02390
uniprot id: A0A0K8J3T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS04975
gene id: 1679721:SD1D_RS04975
uniprot id: A0A0K8J4Z7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1679721:SD1D RS02265
gene id: 1679721:SD1D_RS02265
uniprot id: A0A0K8J3U5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS01705
gene id: 1679721:SD1D_RS01705
uniprot id: A0A0K8J303
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1679721:SD1D RS03870
gene id: 1679721:SD1D_RS03870
uniprot id: A0A0K8J4R4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1679721:SD1D RS04925
gene id: 1679721:SD1D_RS04925
uniprot id: A0A0K8J4Y7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1679721:SD1D RS08510
gene id: 1679721:SD1D_RS08510
uniprot id: A0A0K8J7D9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1679721:SD1D RS00790
gene id: 1679721:SD1D_RS00790
uniprot id: A0A0K8J2M9
names: Similarity
messages: Belongs to the MecA family.

1679721:SD1D RS05325
gene id: 1679721:SD1D_RS05325
uniprot id: A0A0K8J4M7
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1679721:SD1D RS08865
gene id: 1679721:SD1D_RS08865
uniprot id: A0A0K8J6T5
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

1679721:SD1D RS04700
gene id: 1679721:SD1D_RS04700
uniprot id: A0A0K8J4T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS07990
gene id: 1679721:SD1D_RS07990
uniprot id: A0A0K8J689
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1679721:SD1D RS06820
gene id: 1679721:SD1D_RS06820
uniprot id: A0A0K8J621
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1679721:SD1D RS09200
gene id: 1679721:SD1D_RS09200
uniprot id: A0A0K8J7F6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1679721:SD1D RS08170
gene id: 1679721:SD1D_RS08170
uniprot id: A0A0K8J6B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1679721:SD1D RS01250
gene id: 1679721:SD1D_RS01250
uniprot id: A0A0K8J2R9
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS06930
gene id: 1679721:SD1D_RS06930
uniprot id: A0A0K8J6G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1679721:SD1D RS02220
gene id: 1679721:SD1D_RS02220
uniprot id: A0A0K8J3R3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1679721:SD1D RS05470
gene id: 1679721:SD1D_RS05470
uniprot id: A0A0K8J4S4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1679721:SD1D RS03110
gene id: 1679721:SD1D_RS03110
uniprot id: A0A0K8J4A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1679721:SD1D RS10205
gene id: 1679721:SD1D_RS10205
uniprot id: A0A0K8J7Q9
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1679721:SD1D RS04120
gene id: 1679721:SD1D_RS04120
uniprot id: A0A0K8J4F8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1679721:SD1D RS10800
gene id: 1679721:SD1D_RS10800
uniprot id: A0A0K8J8D7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1679721:SD1D RS06130
gene id: 1679721:SD1D_RS06130
uniprot id: A0A0K8J5N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1679721:SD1D RS04690
gene id: 1679721:SD1D_RS04690
uniprot id: A0A0K8J4S9
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

1679721:SD1D RS05140
gene id: 1679721:SD1D_RS05140
uniprot id: A0A0K8J5E5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1679721:SD1D RS10050
gene id: 1679721:SD1D_RS10050
uniprot id: A0A0K8J7M6
names: Similarity
messages: Belongs to the threonine synthase family.

1679721:SD1D RS07705
gene id: 1679721:SD1D_RS07705
uniprot id: A0A0K8J6Q8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1679721:SD1D RS10405
gene id: 1679721:SD1D_RS10405
uniprot id: A0A0K8J7U7
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS01615
gene id: 1679721:SD1D_RS01615
uniprot id: A0A0K8J317
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1679721:SD1D RS04725
gene id: 1679721:SD1D_RS04725
uniprot id: A0A0K8J4U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1679721:SD1D RS08490
gene id: 1679721:SD1D_RS08490
uniprot id: A0A0K8J736
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1679721:SD1D RS01210
gene id: 1679721:SD1D_RS01210
uniprot id: A0A0K8J363
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1679721:SD1D RS01580
gene id: 1679721:SD1D_RS01580
uniprot id: A0A0K8J3I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1679721:SD1D RS09860
gene id: 1679721:SD1D_RS09860
uniprot id: A0A0K8J7L0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1679721:SD1D RS05335
gene id: 1679721:SD1D_RS05335
uniprot id: A0A0K8J5I4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1679721:SD1D RS10435
gene id: 1679721:SD1D_RS10435
uniprot id: A0A0K8J7V0
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS01945
gene id: 1679721:SD1D_RS01945
uniprot id: A0A0K8J3I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1679721:SD1D RS04520
gene id: 1679721:SD1D_RS04520
uniprot id: A0A0K8J467
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1679721:SD1D RS01745
gene id: 1679721:SD1D_RS01745
uniprot id: A0A0K8J344
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1679721:SD1D RS06270
gene id: 1679721:SD1D_RS06270
uniprot id: A0A0K8J646
names: Similarity
messages: Belongs to the ThiD family.

1679721:SD1D RS01930
gene id: 1679721:SD1D_RS01930
uniprot id: A0A0K8J2S7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1679721:SD1D RS08690
gene id: 1679721:SD1D_RS08690
uniprot id: A0A0K8J769
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1679721:SD1D RS08575
gene id: 1679721:SD1D_RS08575
uniprot id: A0A0K8J6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1679721:SD1D RS04130
gene id: 1679721:SD1D_RS04130
uniprot id: A0A0K8J4V3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1679721:SD1D RS11730
gene id: 1679721:SD1D_RS11730
uniprot id: A0A0K8J991
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS08710
gene id: 1679721:SD1D_RS08710
uniprot id: A0A0K8J7H8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1679721:SD1D RS04555
gene id: 1679721:SD1D_RS04555
uniprot id: A0A0K8J546
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1679721:SD1D RS06705
gene id: 1679721:SD1D_RS06705
uniprot id: A0A0K8J6D7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1679721:SD1D RS01450
gene id: 1679721:SD1D_RS01450
uniprot id: A0A0K8J2G4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1679721:SD1D RS01270
gene id: 1679721:SD1D_RS01270
uniprot id: A0A0K8J2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS08755
gene id: 1679721:SD1D_RS08755
uniprot id: A0A0K8J779
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1679721:SD1D RS08580
gene id: 1679721:SD1D_RS08580
uniprot id: A0A0K8J7H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS01400
gene id: 1679721:SD1D_RS01400
uniprot id: A0A0K8J2U2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1679721:SD1D RS05750
gene id: 1679721:SD1D_RS05750
uniprot id: A0A0K8J5G4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1679721:SD1D RS04245
gene id: 1679721:SD1D_RS04245
uniprot id: A0A0K8J4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1679721:SD1D RS01800
gene id: 1679721:SD1D_RS01800
uniprot id: A0A0K8J2Q1
names: Similarity
messages: Belongs to the FlgM family.

1679721:SD1D RS11900
gene id: 1679721:SD1D_RS11900
uniprot id: A0A0K8J8E8
names: Similarity
messages: Belongs to the GerABKA family.

1679721:SD1D RS08210
gene id: 1679721:SD1D_RS08210
uniprot id: A0A0K8J6Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS03400
gene id: 1679721:SD1D_RS03400
uniprot id: A0A0K8J4J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1679721:SD1D RS03855
gene id: 1679721:SD1D_RS03855
uniprot id: A0A0K8J4A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1679721:SD1D RS11925
gene id: 1679721:SD1D_RS11925
uniprot id: A0A0K8J8I4
names: Similarity
messages: Belongs to the thioredoxin family.

1679721:SD1D RS01555
gene id: 1679721:SD1D_RS01555
uniprot id: A0A0K8J3H7
names: Similarity
messages: Belongs to the PspA/IM30 family.

1679721:SD1D RS09280
gene id: 1679721:SD1D_RS09280
uniprot id: A0A0K8J780
names: Similarity
messages: Belongs to the UPF0111 family.

1679721:SD1D RS09125
gene id: 1679721:SD1D_RS09125
uniprot id: A0A0K8J7R5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1679721:SD1D RS06180
gene id: 1679721:SD1D_RS06180
uniprot id: A0A0K8J5P5
names: Similarity
messages: Belongs to the WrbA family.

1679721:SD1D RS05205
gene id: 1679721:SD1D_RS05205
uniprot id: A0A0K8J545
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1679721:SD1D RS05630
gene id: 1679721:SD1D_RS05630
uniprot id: A0A0K8J5S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS02665
gene id: 1679721:SD1D_RS02665
uniprot id: A0A0K8J435
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1679721:SD1D RS05365
gene id: 1679721:SD1D_RS05365
uniprot id: A0A0K8J571
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1679721:SD1D RS04595
gene id: 1679721:SD1D_RS04595
uniprot id: A0A0K8J481
names: Similarity
messages: Belongs to the peptidase M16 family.

1679721:SD1D RS00370
gene id: 1679721:SD1D_RS00370
uniprot id: A0A0K8J2W7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1679721:SD1D RS00820
gene id: 1679721:SD1D_RS00820
uniprot id: A0A0K8J2J8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1679721:SD1D RS01820
gene id: 1679721:SD1D_RS01820
uniprot id: A0A0K8J358
names: Similarity
messages: Belongs to the bacterial flagellin family.

1679721:SD1D RS10250
gene id: 1679721:SD1D_RS10250
uniprot id: A0A0K8J7R7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS03095
gene id: 1679721:SD1D_RS03095
uniprot id: A0A0K8J3I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1679721:SD1D RS08095
gene id: 1679721:SD1D_RS08095
uniprot id: A0A0K8J796
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1679721:SD1D RS05545
gene id: 1679721:SD1D_RS05545
uniprot id: A0A0K8J4T7
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1679721:SD1D RS04055
gene id: 1679721:SD1D_RS04055
uniprot id: A0A0K8J4U0
names: Similarity
messages: Belongs to the transpeptidase family.

1679721:SD1D RS05290
gene id: 1679721:SD1D_RS05290
uniprot id: A0A0K8J5H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1679721:SD1D RS04665
gene id: 1679721:SD1D_RS04665
uniprot id: A0A0K8J4S2
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

1679721:SD1D RS07810
gene id: 1679721:SD1D_RS07810
uniprot id: A0A0K8J6T1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1679721:SD1D RS01765
gene id: 1679721:SD1D_RS01765
uniprot id: A0A0K8J3F3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1679721:SD1D RS06580
gene id: 1679721:SD1D_RS06580
uniprot id: A0A0K8J673
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS01280
gene id: 1679721:SD1D_RS01280
uniprot id: A0A0K8J3B5
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS05445
gene id: 1679721:SD1D_RS05445
uniprot id: A0A0K8J4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1679721:SD1D RS10925
gene id: 1679721:SD1D_RS10925
uniprot id: A0A0K8J8F7
names: Similarity
messages: Belongs to the CvfB family.

1679721:SD1D RS08010
gene id: 1679721:SD1D_RS08010
uniprot id: A0A0K8J6P8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS05700
gene id: 1679721:SD1D_RS05700
uniprot id: A0A0K8J5F7
names: Similarity
messages: Belongs to the transpeptidase family.

1679721:SD1D RS01605
gene id: 1679721:SD1D_RS01605
uniprot id: A0A0K8J3I6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1679721:SD1D RS03635
gene id: 1679721:SD1D_RS03635
uniprot id: A0A0K8J465
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1679721:SD1D RS09235
gene id: 1679721:SD1D_RS09235
uniprot id: A0A0K8J6Z0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1679721:SD1D RS03545
gene id: 1679721:SD1D_RS03545
uniprot id: A0A0K8J460
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1679721:SD1D RS02640
gene id: 1679721:SD1D_RS02640
uniprot id: A0A0K8J429
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1679721:SD1D RS11030
gene id: 1679721:SD1D_RS11030
uniprot id: A0A0K8J831
names: Similarity
messages: Belongs to the manganese catalase family.

1679721:SD1D RS07215
gene id: 1679721:SD1D_RS07215
uniprot id: A0A0K8J6L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
messages: Membrane

1679721:SD1D RS04160
gene id: 1679721:SD1D_RS04160
uniprot id: A0A0K8J4I7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1679721:SD1D RS01700
gene id: 1679721:SD1D_RS01700
uniprot id: A0A0K8J2N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1679721:SD1D RS05210
gene id: 1679721:SD1D_RS05210
uniprot id: A0A0K8J5H3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1679721:SD1D RS01560
gene id: 1679721:SD1D_RS01560
uniprot id: A0A0K8J3C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1679721:SD1D RS00990
gene id: 1679721:SD1D_RS00990
uniprot id: A0A0K8J286
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1679721:SD1D RS07580
gene id: 1679721:SD1D_RS07580
uniprot id: A0A0K8J6M7
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS04510
gene id: 1679721:SD1D_RS04510
uniprot id: A0A0K8J530
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS02510
gene id: 1679721:SD1D_RS02510
uniprot id: A0A0K8J403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1679721:SD1D RS09555
gene id: 1679721:SD1D_RS09555
uniprot id: A0A0K8J815
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1679721:SD1D RS11725
gene id: 1679721:SD1D_RS11725
uniprot id: A0A0K8J8A8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1679721:SD1D RS06220
gene id: 1679721:SD1D_RS06220
uniprot id: A0A0K8J638
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1679721:SD1D RS02180
gene id: 1679721:SD1D_RS02180
uniprot id: A0A0K8J3C6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1679721:SD1D RS02345
gene id: 1679721:SD1D_RS02345
uniprot id: A0A0K8J3F2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1679721:SD1D RS11055
gene id: 1679721:SD1D_RS11055
uniprot id: A0A0K8J835
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

1679721:SD1D RS07510
gene id: 1679721:SD1D_RS07510
uniprot id: A0A0K8J6E8
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1679721:SD1D RS04035
gene id: 1679721:SD1D_RS04035
uniprot id: A0A0K8J4G0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1679721:SD1D RS05665
gene id: 1679721:SD1D_RS05665
uniprot id: A0A0K8J5E8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1679721:SD1D RS04250
gene id: 1679721:SD1D_RS04250
uniprot id: A0A0K8J4Y8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS03885
gene id: 1679721:SD1D_RS03885
uniprot id: A0A0K8J3V0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS08495
gene id: 1679721:SD1D_RS08495
uniprot id: A0A0K8J6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1679721:SD1D RS12020
gene id: 1679721:SD1D_RS12020
uniprot id: A0A0K8J8W3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1679721:SD1D RS04095
gene id: 1679721:SD1D_RS04095
uniprot id: A0A0K8J4F5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1679721:SD1D RS06055
gene id: 1679721:SD1D_RS06055
uniprot id: A0A0K8J5M0
names: Similarity
messages: Belongs to the DtxR/MntR family.

1679721:SD1D RS09495
gene id: 1679721:SD1D_RS09495
uniprot id: A0A0K8J727
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1679721:SD1D RS08005
gene id: 1679721:SD1D_RS08005
uniprot id: A0A0K8J6X5
names: Similarity
messages: Belongs to the TrpC family.

1679721:SD1D RS02025
gene id: 1679721:SD1D_RS02025
uniprot id: A0A0K8J393
names: Similarity
messages: Belongs to the GARS family.

1679721:SD1D RS01895
gene id: 1679721:SD1D_RS01895
uniprot id: A0A0K8J3H2
names: Similarity
messages: Belongs to the peptidase A8 family.

1679721:SD1D RS02660
gene id: 1679721:SD1D_RS02660
uniprot id: A0A0K8J3L9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1679721:SD1D RS10280
gene id: 1679721:SD1D_RS10280
uniprot id: A0A0K8J7G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS03795
gene id: 1679721:SD1D_RS03795
uniprot id: A0A0K8J4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1679721:SD1D RS02570
gene id: 1679721:SD1D_RS02570
uniprot id: A0A0K8J3J3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1679721:SD1D RS02290
gene id: 1679721:SD1D_RS02290
uniprot id: A0A0K8J3S5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1679721:SD1D RS10970
gene id: 1679721:SD1D_RS10970
uniprot id: A0A0K8J8Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1679721:SD1D RS03010
gene id: 1679721:SD1D_RS03010
uniprot id: A0A0K8J491
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS10835
gene id: 1679721:SD1D_RS10835
uniprot id: A0A0K8J7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1679721:SD1D RS01020
gene id: 1679721:SD1D_RS01020
uniprot id: A0A0K8J2N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

1679721:SD1D RS06935
gene id: 1679721:SD1D_RS06935
uniprot id: A0A0K8J6C1
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1679721:SD1D RS08905
gene id: 1679721:SD1D_RS08905
uniprot id: A0A0K8J7M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1679721:SD1D RS01875
gene id: 1679721:SD1D_RS01875
uniprot id: A0A0K8J368
names: Function
messages: Involved in the transposition of the insertion sequence.

1679721:SD1D RS07495
gene id: 1679721:SD1D_RS07495
uniprot id: A0A0K8J6J4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1679721:SD1D RS02150
gene id: 1679721:SD1D_RS02150
uniprot id: A0A0K8J3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS01325
gene id: 1679721:SD1D_RS01325
uniprot id: A0A0K8J2T2
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS04065
gene id: 1679721:SD1D_RS04065
uniprot id: A0A0K8J3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1679721:SD1D RS04105
gene id: 1679721:SD1D_RS04105
uniprot id: A0A0K8J4U8
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1679721:SD1D RS04145
gene id: 1679721:SD1D_RS04145
uniprot id: A0A0K8J4G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1679721:SD1D RS05155
gene id: 1679721:SD1D_RS05155
uniprot id: A0A0K8J533
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1679721:SD1D RS04330
gene id: 1679721:SD1D_RS04330
uniprot id: A0A0K8J4Z1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1679721:SD1D RS05725
gene id: 1679721:SD1D_RS05725
uniprot id: A0A0K8J5G0
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS08990
gene id: 1679721:SD1D_RS08990
uniprot id: A0A0K8J7P3
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1679721:SD1D RS05360
gene id: 1679721:SD1D_RS05360
uniprot id: A0A0K8J5J0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1679721:SD1D RS10905
gene id: 1679721:SD1D_RS10905
uniprot id: A0A0K8J808
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1679721:SD1D RS08940
gene id: 1679721:SD1D_RS08940
uniprot id: A0A0K8J7N3
names: Similarity
messages: Belongs to the serpin family.

1679721:SD1D RS08360
gene id: 1679721:SD1D_RS08360
uniprot id: A0A0K8J722
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1679721:SD1D RS02500
gene id: 1679721:SD1D_RS02500
uniprot id: A0A0K8J343
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS09105
gene id: 1679721:SD1D_RS09105
uniprot id: A0A0K8J7D5
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1679721:SD1D RS01305
gene id: 1679721:SD1D_RS01305
uniprot id: A0A0K8J3B9
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1679721:SD1D RS01670
gene id: 1679721:SD1D_RS01670
uniprot id: A0A0K8J2M8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1679721:SD1D RS01030
gene id: 1679721:SD1D_RS01030
uniprot id: A0A0K8J332
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1679721:SD1D RS02940
gene id: 1679721:SD1D_RS02940
uniprot id: A0A0K8J4B6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1679721:SD1D RS04470
gene id: 1679721:SD1D_RS04470
uniprot id: A0A0K8J459
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1679721:SD1D RS10555
gene id: 1679721:SD1D_RS10555
uniprot id: A0A0K8J8B1
names: Caution
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1679721:SD1D RS11075
gene id: 1679721:SD1D_RS11075
uniprot id: A0A0K8J8H4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1679721:SD1D RS09315
gene id: 1679721:SD1D_RS09315
uniprot id: A0A0K8J7T9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1679721:SD1D RS10295
gene id: 1679721:SD1D_RS10295
uniprot id: A0A0K8J834
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS05295
gene id: 1679721:SD1D_RS05295
uniprot id: A0A0K8J555
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1679721:SD1D RS00585
gene id: 1679721:SD1D_RS00585
uniprot id: A0A0K8J2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1679721:SD1D RS00710
gene id: 1679721:SD1D_RS00710
uniprot id: A0A0K8J321
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1679721:SD1D RS10550
gene id: 1679721:SD1D_RS10550
uniprot id: A0A0K8J8S3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1679721:SD1D RS01265
gene id: 1679721:SD1D_RS01265
uniprot id: A0A0K8J2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS11535
gene id: 1679721:SD1D_RS11535
uniprot id: A0A0K8J981
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1679721:SD1D RS10255
gene id: 1679721:SD1D_RS10255
uniprot id: A0A0K8J7F7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1679721:SD1D RS11375
gene id: 1679721:SD1D_RS11375
uniprot id: A0A0K8J845
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1679721:SD1D RS09955
gene id: 1679721:SD1D_RS09955
uniprot id: A0A0K8J7L8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

1679721:SD1D RS08460
gene id: 1679721:SD1D_RS08460
uniprot id: A0A0K8J734
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS09485
gene id: 1679721:SD1D_RS09485
uniprot id: A0A0K8J7K9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1679721:SD1D RS02700
gene id: 1679721:SD1D_RS02700
uniprot id: A0A0K8J3L8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1679721:SD1D RS10540
gene id: 1679721:SD1D_RS10540
uniprot id: A0A0K8J7P0
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS12035
gene id: 1679721:SD1D_RS12035
uniprot id: A0A0K8J9E5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1679721:SD1D RS05720
gene id: 1679721:SD1D_RS05720
uniprot id: A0A0K8J4X0
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS01620
gene id: 1679721:SD1D_RS01620
uniprot id: A0A0K8J2L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1679721:SD1D RS00695
gene id: 1679721:SD1D_RS00695
uniprot id: A0A0K8J2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1679721:SD1D RS01825
gene id: 1679721:SD1D_RS01825
uniprot id: A0A0K8J2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1679721:SD1D RS05605
gene id: 1679721:SD1D_RS05605
uniprot id: A0A0K8J5R4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1679721:SD1D RS09480
gene id: 1679721:SD1D_RS09480
uniprot id: A0A0K8J7Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1679721:SD1D RS04150
gene id: 1679721:SD1D_RS04150
uniprot id: A0A0K8J4W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1679721:SD1D RS00470
gene id: 1679721:SD1D_RS00470
uniprot id: A0A0K8J2Y5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1679721:SD1D RS04240
gene id: 1679721:SD1D_RS04240
uniprot id: A0A0K8J419
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1679721:SD1D RS10350
gene id: 1679721:SD1D_RS10350
uniprot id: A0A0K8J846
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1679721:SD1D RS08355
gene id: 1679721:SD1D_RS08355
uniprot id: A0A0K8J7B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1679721:SD1D RS04920
gene id: 1679721:SD1D_RS04920
uniprot id: A0A0K8J4D9
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1679721:SD1D RS11415
gene id: 1679721:SD1D_RS11415
uniprot id: A0A0K8J8L2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1679721:SD1D RS11015
gene id: 1679721:SD1D_RS11015
uniprot id: A0A0K8J8U5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1679721:SD1D RS10605
gene id: 1679721:SD1D_RS10605
uniprot id: A0A0K8J8B8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1679721:SD1D RS11560
gene id: 1679721:SD1D_RS11560
uniprot id: A0A0K8J982
names: Similarity
messages: Belongs to the Fur family.

1679721:SD1D RS01840
gene id: 1679721:SD1D_RS01840
uniprot id: A0A0K8J3G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1679721:SD1D RS05375
gene id: 1679721:SD1D_RS05375
uniprot id: A0A0K8J581
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1679721:SD1D RS01610
gene id: 1679721:SD1D_RS01610
uniprot id: A0A0K8J3D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1679721:SD1D RS02115
gene id: 1679721:SD1D_RS02115
uniprot id: A0A0K8J3S7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1679721:SD1D RS05135
gene id: 1679721:SD1D_RS05135
uniprot id: A0A0K8J5F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1679721:SD1D RS07775
gene id: 1679721:SD1D_RS07775
uniprot id: A0A0K8J6I4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1679721:SD1D RS07790
gene id: 1679721:SD1D_RS07790
uniprot id: A0A0K8J6W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1679721:SD1D RS08245
gene id: 1679721:SD1D_RS08245
uniprot id: A0A0K8J6D3
names: Similarity
messages: Belongs to the citrate synthase family.

1679721:SD1D RS05710
gene id: 1679721:SD1D_RS05710
uniprot id: A0A0K8J5R5
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1679721:SD1D RS02845
gene id: 1679721:SD1D_RS02845
uniprot id: A0A0K8J437
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1679721:SD1D RS04740
gene id: 1679721:SD1D_RS04740
uniprot id: A0A0K8J4T9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1679721:SD1D RS04615
gene id: 1679721:SD1D_RS04615
uniprot id: A0A0K8J4R3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1679721:SD1D RS10030
gene id: 1679721:SD1D_RS10030
uniprot id: A0A0K8J7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS10085
gene id: 1679721:SD1D_RS10085
uniprot id: A0A0K8J7C3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1679721:SD1D RS01405
gene id: 1679721:SD1D_RS01405
uniprot id: A0A0K8J3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1679721:SD1D RS10445
gene id: 1679721:SD1D_RS10445
uniprot id: A0A0K8J8H6
names: Similarity
messages: Belongs to the UPF0145 family.

1679721:SD1D RS08935
gene id: 1679721:SD1D_RS08935
uniprot id: A0A0K8J7M5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS08020
gene id: 1679721:SD1D_RS08020
uniprot id: A0A0K8J763
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1679721:SD1D RS02020
gene id: 1679721:SD1D_RS02020
uniprot id: A0A0K8J3M1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1679721:SD1D RS04085
gene id: 1679721:SD1D_RS04085
uniprot id: A0A0K8J4H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1679721:SD1D RS01465
gene id: 1679721:SD1D_RS01465
uniprot id: A0A0K8J3A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1679721:SD1D RS03970
gene id: 1679721:SD1D_RS03970
uniprot id: A0A0K8J4D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1679721:SD1D RS11570
gene id: 1679721:SD1D_RS11570
uniprot id: A0A0K8J8D0
names: Subcellular Location Annotation
messages: Cytoplasm

1679721:SD1D RS07460
gene id: 1679721:SD1D_RS07460
uniprot id: A0A0K8J6D9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1679721:SD1D RS09705
gene id: 1679721:SD1D_RS09705
uniprot id: A0A0K8J847
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1679721:SD1D RS09585
gene id: 1679721:SD1D_RS09585
uniprot id: A0A0K8J801
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1679721:SD1D RS01585
gene id: 1679721:SD1D_RS01585
uniprot id: A0A0K8J3D0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1679721:SD1D RS00040
gene id: 1679721:SD1D_RS00040
uniprot id: A0A0K8J2N9
names: Similarity
messages: Belongs to the class-I fumarase family.

1679721:SD1D RS11825
gene id: 1679721:SD1D_RS11825
uniprot id: A0A0K8J8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1679721:SD1D RS09720
gene id: 1679721:SD1D_RS09720
uniprot id: A0A0K8J7I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1679721:SD1D RS04450
gene id: 1679721:SD1D_RS04450
uniprot id: A0A0K8J4M1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1679721:SD1D RS10220
gene id: 1679721:SD1D_RS10220
uniprot id: A0A0K8J8C0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1679721:SD1D RS09255
gene id: 1679721:SD1D_RS09255
uniprot id: A0A0K8J777
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1679721:SD1D RS02565
gene id: 1679721:SD1D_RS02565
uniprot id: A0A0K8J3X4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1679721:SD1D RS05465
gene id: 1679721:SD1D_RS05465
uniprot id: A0A0K8J5B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1679721:SD1D RS01830
gene id: 1679721:SD1D_RS01830
uniprot id: A0A0K8J331
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1679721:SD1D RS10130
gene id: 1679721:SD1D_RS10130
uniprot id: A0A0K8J7P2
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS08915
gene id: 1679721:SD1D_RS08915
uniprot id: A0A0K8J7A2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1679721:SD1D RS09005
gene id: 1679721:SD1D_RS09005
uniprot id: A0A0K8J6V3
names: Similarity
messages: Belongs to the Fur family.

1679721:SD1D RS08760
gene id: 1679721:SD1D_RS08760
uniprot id: A0A0K8J704
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1679721:SD1D RS08520
gene id: 1679721:SD1D_RS08520
uniprot id: A0A0K8J6X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1679721:SD1D RS11980
gene id: 1679721:SD1D_RS11980
uniprot id: A0A0K8J9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1679721:SD1D RS05940
gene id: 1679721:SD1D_RS05940
uniprot id: A0A0K8J504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1679721:SD1D RS05450
gene id: 1679721:SD1D_RS05450
uniprot id: A0A0K8J5B2
names: Similarity
messages: Belongs to the CinA family.

1679721:SD1D RS06715
gene id: 1679721:SD1D_RS06715
uniprot id: A0A0K8J600
names: Similarity
messages: Belongs to the UPF0045 family.

1679721:SD1D RS03140
gene id: 1679721:SD1D_RS03140
uniprot id: A0A0K8J3X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1679721:SD1D RS02375
gene id: 1679721:SD1D_RS02375
uniprot id: A0A0K8J313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1679721:SD1D RS02320
gene id: 1679721:SD1D_RS02320
uniprot id: A0A0K8J3E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1679721:SD1D RS05195
gene id: 1679721:SD1D_RS05195
uniprot id: A0A0K8J536
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1679721:SD1D RS01205
gene id: 1679721:SD1D_RS01205
uniprot id: A0A0K8J3A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1679721:SD1D RS02790
gene id: 1679721:SD1D_RS02790
uniprot id: A0A0K8J461
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1679721:SD1D RS10370
gene id: 1679721:SD1D_RS10370
uniprot id: A0A0K8J8F3
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1679721:SD1D RS04760
gene id: 1679721:SD1D_RS04760
uniprot id: A0A0K8J575
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1679721:SD1D RS02255
gene id: 1679721:SD1D_RS02255
uniprot id: A0A0K8J2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1679721:SD1D RS01310
gene id: 1679721:SD1D_RS01310
uniprot id: A0A0K8J381
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1679721:SD1D RS08465
gene id: 1679721:SD1D_RS08465
uniprot id: A0A0K8J6W2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1679721:SD1D RS03145
gene id: 1679721:SD1D_RS03145
uniprot id: A0A0K8J3J2
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1679721:SD1D RS09275
gene id: 1679721:SD1D_RS09275
uniprot id: A0A0K8J7H1
names: Subcellular Location Annotation
messages: Membrane

1679721:SD1D RS00965
gene id: 1679721:SD1D_RS00965
uniprot id: A0A0K8J2Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1679721:SD1D RS02110
gene id: 1679721:SD1D_RS02110
uniprot id: A0A0K8J3A9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1679721:SD1D RS02545
gene id: 1679721:SD1D_RS02545
uniprot id: A0A0K8J3I9
names: Subcellular Location Annotation
messages: Cytoplasm

1679721:SD1D RS08965
gene id: 1679721:SD1D_RS08965
uniprot id: A0A0K8J7N6
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1679721:SD1D RS06910
gene id: 1679721:SD1D_RS06910
uniprot id: A0A0K8J6G3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1679721:SD1D RS08110
gene id: 1679721:SD1D_RS08110
uniprot id: A0A0K8J6R3
names: Similarity
messages: Belongs to the UPF0237 family.

1679721:SD1D RS10630
gene id: 1679721:SD1D_RS10630
uniprot id: A0A0K8J8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS05920
gene id: 1679721:SD1D_RS05920
uniprot id: A0A0K8J5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1679721:SD1D RS10870
gene id: 1679721:SD1D_RS10870
uniprot id: A0A0K8J8W5
names: Similarity
messages: Belongs to the UPF0735 family.

1679721:SD1D RS01900
gene id: 1679721:SD1D_RS01900
uniprot id: A0A0K8J372
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1679721:SD1D RS00760
gene id: 1679721:SD1D_RS00760
uniprot id: A0A0K8J2X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1679721:SD1D RS08975
gene id: 1679721:SD1D_RS08975
uniprot id: A0A0K8J737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1679721:SD1D RS09415
gene id: 1679721:SD1D_RS09415
uniprot id: A0A0K8J799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1679721:SD1D RS10910
gene id: 1679721:SD1D_RS10910
uniprot id: A0A0K8J7V5
names: Similarity
messages: Belongs to the peptidase C40 family.

1679721:SD1D RS08165
gene id: 1679721:SD1D_RS08165
uniprot id: A0A0K8J6S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1679721:SD1D RS09920
gene id: 1679721:SD1D_RS09920
uniprot id: A0A0K8J884
names: Similarity
messages: Belongs to the IMPACT family.

1679721:SD1D RS11005
gene id: 1679721:SD1D_RS11005
uniprot id: A0A0K8J825
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1679721:SD1D RS06735
gene id: 1679721:SD1D_RS06735
uniprot id: A0A0K8J685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane