1652495:ccrud RS05045
gene id: 1652495:ccrud_RS05045
uniprot id: A0A172QSJ1
names: Subcellular Location Annotation
messages: Cytoplasm

1652495:ccrud RS10345
gene id: 1652495:ccrud_RS10345
uniprot id: A0A172QV90
names: Cofactor
messages: Can also use Mn(2+) ion.

1652495:ccrud RS08825
gene id: 1652495:ccrud_RS08825
uniprot id: A0A172QUA7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1652495:ccrud RS09125
gene id: 1652495:ccrud_RS09125
uniprot id: A0A172QUK2
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1652495:ccrud RS02650
gene id: 1652495:ccrud_RS02650
uniprot id: A0A172QR93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1652495:ccrud RS02115
gene id: 1652495:ccrud_RS02115
uniprot id: A0A172QR19
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1652495:ccrud RS13770
gene id: 1652495:ccrud_RS13770
uniprot id: A0A172QXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1652495:ccrud RS08620
gene id: 1652495:ccrud_RS08620
uniprot id: A0A172QU68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1652495:ccrud RS11965
gene id: 1652495:ccrud_RS11965
uniprot id: A0A172QW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS13715
gene id: 1652495:ccrud_RS13715
uniprot id: A0A172QWX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1652495:ccrud RS07105
gene id: 1652495:ccrud_RS07105
uniprot id: A0A172QTG2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1652495:ccrud RS02815
gene id: 1652495:ccrud_RS02815
uniprot id: A0A172QRD3
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1652495:ccrud RS05540
gene id: 1652495:ccrud_RS05540
uniprot id: A0A172QSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1652495:ccrud RS06495
gene id: 1652495:ccrud_RS06495
uniprot id: A0A172QT66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS09035
gene id: 1652495:ccrud_RS09035
uniprot id: A0A172QUK4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1652495:ccrud RS05005
gene id: 1652495:ccrud_RS05005
uniprot id: A0A172QSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1652495:ccrud RS07675
gene id: 1652495:ccrud_RS07675
uniprot id: A0A172QTU9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1652495:ccrud RS08355
gene id: 1652495:ccrud_RS08355
uniprot id: A0A172QU37
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1652495:ccrud RS08980
gene id: 1652495:ccrud_RS08980
uniprot id: A0A172QUJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1652495:ccrud RS07560
gene id: 1652495:ccrud_RS07560
uniprot id: A0A172QTS0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1652495:ccrud RS13610
gene id: 1652495:ccrud_RS13610
uniprot id: A0A172QWP3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1652495:ccrud RS13775
gene id: 1652495:ccrud_RS13775
uniprot id: A0A172QWY3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1652495:ccrud RS03245
gene id: 1652495:ccrud_RS03245
uniprot id: A0A172QRL6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-73 and Arg-76) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1652495:ccrud RS10580
gene id: 1652495:ccrud_RS10580
uniprot id: A0A172QXE2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1652495:ccrud RS13555
gene id: 1652495:ccrud_RS13555
uniprot id: A0A172QWN5
names: Similarity
messages: Belongs to the UPF0371 family.

1652495:ccrud RS04155
gene id: 1652495:ccrud_RS04155
uniprot id: A0A172QS16
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1652495:ccrud RS11005
gene id: 1652495:ccrud_RS11005
uniprot id: A0A172QVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS04535
gene id: 1652495:ccrud_RS04535
uniprot id: A0A172QS74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1652495:ccrud RS07820
gene id: 1652495:ccrud_RS07820
uniprot id: A0A172QTW6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1652495:ccrud RS12640
gene id: 1652495:ccrud_RS12640
uniprot id: A0A172QW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS03045
gene id: 1652495:ccrud_RS03045
uniprot id: A0A172QX14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1652495:ccrud RS03900
gene id: 1652495:ccrud_RS03900
uniprot id: A0A172QRX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1652495:ccrud RS12170
gene id: 1652495:ccrud_RS12170
uniprot id: A0A172QW52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1652495:ccrud RS07920
gene id: 1652495:ccrud_RS07920
uniprot id: A0A172QTW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS10540
gene id: 1652495:ccrud_RS10540
uniprot id: A0A172QXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1652495:ccrud RS00685
gene id: 1652495:ccrud_RS00685
uniprot id: A0A172QQC0
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS11545
gene id: 1652495:ccrud_RS11545
uniprot id: A0A172QVM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1652495:ccrud RS12335
gene id: 1652495:ccrud_RS12335
uniprot id: A0A172QW82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS02910
gene id: 1652495:ccrud_RS02910
uniprot id: A0A172QRE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS10745
gene id: 1652495:ccrud_RS10745
uniprot id: A0A172QVA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1652495:ccrud RS04810
gene id: 1652495:ccrud_RS04810
uniprot id: A0A172QSE6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1652495:ccrud RS10095
gene id: 1652495:ccrud_RS10095
uniprot id: A0A172QUY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1652495:ccrud RS10405
gene id: 1652495:ccrud_RS10405
uniprot id: A0A172QV96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1652495:ccrud RS09160
gene id: 1652495:ccrud_RS09160
uniprot id: A0A172QUM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1652495:ccrud RS12715
gene id: 1652495:ccrud_RS12715
uniprot id: A0A172QW92
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS06465
gene id: 1652495:ccrud_RS06465
uniprot id: A0A172QT57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1652495:ccrud RS01125
gene id: 1652495:ccrud_RS01125
uniprot id: A0A172QQK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1652495:ccrud RS05210
gene id: 1652495:ccrud_RS05210
uniprot id: A0A172QXC4
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS13700
gene id: 1652495:ccrud_RS13700
uniprot id: A0A172QWZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS01040
gene id: 1652495:ccrud_RS01040
uniprot id: A0A172QWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1652495:ccrud RS05715
gene id: 1652495:ccrud_RS05715
uniprot id: A0A172QSU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1652495:ccrud RS09600
gene id: 1652495:ccrud_RS09600
uniprot id: A0A172QUV9
names: Similarity
messages: Belongs to the peptidase C40 family.

1652495:ccrud RS06845
gene id: 1652495:ccrud_RS06845
uniprot id: A0A172QTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1652495:ccrud RS11130
gene id: 1652495:ccrud_RS11130
uniprot id: A0A172QVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1652495:ccrud RS08535
gene id: 1652495:ccrud_RS08535
uniprot id: A0A172QU71
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1652495:ccrud RS11585
gene id: 1652495:ccrud_RS11585
uniprot id: A0A172QVV6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1652495:ccrud RS05505
gene id: 1652495:ccrud_RS05505
uniprot id: A0A172QSP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1652495:ccrud RS10635
gene id: 1652495:ccrud_RS10635
uniprot id: A0A172QV92
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1652495:ccrud RS07800
gene id: 1652495:ccrud_RS07800
uniprot id: A0A172QTY9
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1652495:ccrud RS02895
gene id: 1652495:ccrud_RS02895
uniprot id: A0A172QRG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1652495:ccrud RS05075
gene id: 1652495:ccrud_RS05075
uniprot id: A0A172QSH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1652495:ccrud RS03980
gene id: 1652495:ccrud_RS03980
uniprot id: A0A172QX29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1652495:ccrud RS10395
gene id: 1652495:ccrud_RS10395
uniprot id: A0A172QV35
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07625
gene id: 1652495:ccrud_RS07625
uniprot id: A0A172QTT9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS02620
gene id: 1652495:ccrud_RS02620
uniprot id: A0A172QRA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1652495:ccrud RS10750
gene id: 1652495:ccrud_RS10750
uniprot id: A0A172QVG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1652495:ccrud RS09935
gene id: 1652495:ccrud_RS09935
uniprot id: A0A172QUV8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1652495:ccrud RS10340
gene id: 1652495:ccrud_RS10340
uniprot id: A0A172QV25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1652495:ccrud RS05010
gene id: 1652495:ccrud_RS05010
uniprot id: A0A172QSG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1652495:ccrud RS11840
gene id: 1652495:ccrud_RS11840
uniprot id: A0A172QXG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1652495:ccrud RS11485
gene id: 1652495:ccrud_RS11485
uniprot id: A0A172QVL8
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS02270
gene id: 1652495:ccrud_RS02270
uniprot id: A0A172QR64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1652495:ccrud RS07320
gene id: 1652495:ccrud_RS07320
uniprot id: A0A172QTL7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1652495:ccrud RS10825
gene id: 1652495:ccrud_RS10825
uniprot id: A0A172QVJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1652495:ccrud RS04975
gene id: 1652495:ccrud_RS04975
uniprot id: A0A172QSG3
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS01795
gene id: 1652495:ccrud_RS01795
uniprot id: A0A172QQW5
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS13990
gene id: 1652495:ccrud_RS13990
uniprot id: A0A172QXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1652495:ccrud RS04095
gene id: 1652495:ccrud_RS04095
uniprot id: A0A172QS10
names: Similarity
messages: Belongs to the AccD/PCCB family.

1652495:ccrud RS10025
gene id: 1652495:ccrud_RS10025
uniprot id: A0A172QUX0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1652495:ccrud RS12665
gene id: 1652495:ccrud_RS12665
uniprot id: A0A172QW73
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1652495:ccrud RS07015
gene id: 1652495:ccrud_RS07015
uniprot id: A0A172QTL0
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS01825
gene id: 1652495:ccrud_RS01825
uniprot id: A0A172QQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1652495:ccrud RS05765
gene id: 1652495:ccrud_RS05765
uniprot id: A0A172QSV9
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03445
gene id: 1652495:ccrud_RS03445
uniprot id: A0A172QRR3
names: Similarity
messages: Belongs to the citrate synthase family.

1652495:ccrud RS07790
gene id: 1652495:ccrud_RS07790
uniprot id: A0A172QTZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1652495:ccrud RS06840
gene id: 1652495:ccrud_RS06840
uniprot id: A0A172QTD5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1652495:ccrud RS08425
gene id: 1652495:ccrud_RS08425
uniprot id: A0A172QU46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1652495:ccrud RS11920
gene id: 1652495:ccrud_RS11920
uniprot id: A0A172QVV2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07395
gene id: 1652495:ccrud_RS07395
uniprot id: A0A172QTK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1652495:ccrud RS05835
gene id: 1652495:ccrud_RS05835
uniprot id: A0A172QT09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1652495:ccrud RS01635
gene id: 1652495:ccrud_RS01635
uniprot id: A0A172QQU0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1652495:ccrud RS09465
gene id: 1652495:ccrud_RS09465
uniprot id: A0A172QUN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1652495:ccrud RS05300
gene id: 1652495:ccrud_RS05300
uniprot id: A0A172QX54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1652495:ccrud RS04755
gene id: 1652495:ccrud_RS04755
uniprot id: A0A172QX44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1652495:ccrud RS08670
gene id: 1652495:ccrud_RS08670
uniprot id: A0A172QUF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS11520
gene id: 1652495:ccrud_RS11520
uniprot id: A0A172QVT7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1652495:ccrud RS10235
gene id: 1652495:ccrud_RS10235
uniprot id: A0A172QV68
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1652495:ccrud RS11200
gene id: 1652495:ccrud_RS11200
uniprot id: A0A172QVP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1652495:ccrud RS05515
gene id: 1652495:ccrud_RS05515
uniprot id: A0A172QXD2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1652495:ccrud RS11100
gene id: 1652495:ccrud_RS11100
uniprot id: A0A172QVM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1652495:ccrud RS01345
gene id: 1652495:ccrud_RS01345
uniprot id: A0A172QQP0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1652495:ccrud RS13160
gene id: 1652495:ccrud_RS13160
uniprot id: A0A172QWH0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS06535
gene id: 1652495:ccrud_RS06535
uniprot id: A0A172QXF1
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1652495:ccrud RS09730
gene id: 1652495:ccrud_RS09730
uniprot id: A0A172QUR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1652495:ccrud RS01845
gene id: 1652495:ccrud_RS01845
uniprot id: A0A172QQV2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1652495:ccrud RS11880
gene id: 1652495:ccrud_RS11880
uniprot id: A0A172QW03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS12575
gene id: 1652495:ccrud_RS12575
uniprot id: A0A172QW60
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1652495:ccrud RS00165
gene id: 1652495:ccrud_RS00165
uniprot id: A0A172QQ52
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS00030
gene id: 1652495:ccrud_RS00030
uniprot id: A0A172QQ31
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1652495:ccrud RS07970
gene id: 1652495:ccrud_RS07970
uniprot id: A0A172QTW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS05825
gene id: 1652495:ccrud_RS05825
uniprot id: A0A172QSX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1652495:ccrud RS02580
gene id: 1652495:ccrud_RS02580
uniprot id: A0A172QRA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1652495:ccrud RS04175
gene id: 1652495:ccrud_RS04175
uniprot id: A0A172QS31
names: Similarity
messages: Belongs to the FPG family.

1652495:ccrud RS01000
gene id: 1652495:ccrud_RS01000
uniprot id: A0A172QQG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS11170
gene id: 1652495:ccrud_RS11170
uniprot id: A0A172QVH0
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1652495:ccrud RS11365
gene id: 1652495:ccrud_RS11365
uniprot id: A0A172QVS6
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1652495:ccrud RS03035
gene id: 1652495:ccrud_RS03035
uniprot id: A0A172QRI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1652495:ccrud RS10905
gene id: 1652495:ccrud_RS10905
uniprot id: A0A172QVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS07305
gene id: 1652495:ccrud_RS07305
uniprot id: A0A172QTP4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1652495:ccrud RS08330
gene id: 1652495:ccrud_RS08330
uniprot id: A0A172QU87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1652495:ccrud RS10435
gene id: 1652495:ccrud_RS10435
uniprot id: A0A172QV52
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS01585
gene id: 1652495:ccrud_RS01585
uniprot id: A0A172QQR8
names: Subcellular Location Annotation
messages: Cytoplasm

1652495:ccrud RS06000
gene id: 1652495:ccrud_RS06000
uniprot id: A0A172QSW5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1652495:ccrud RS13710
gene id: 1652495:ccrud_RS13710
uniprot id: A0A172QWZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1652495:ccrud RS11435
gene id: 1652495:ccrud_RS11435
uniprot id: A0A172QVU7
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS00320
gene id: 1652495:ccrud_RS00320
uniprot id: A0A172QQ54
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS05700
gene id: 1652495:ccrud_RS05700
uniprot id: A0A172QSY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1652495:ccrud RS08280
gene id: 1652495:ccrud_RS08280
uniprot id: A0A172QU76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS13270
gene id: 1652495:ccrud_RS13270
uniprot id: A0A172QWI7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

1652495:ccrud RS10740
gene id: 1652495:ccrud_RS10740
uniprot id: A0A172QVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1652495:ccrud RS01220
gene id: 1652495:ccrud_RS01220
uniprot id: A0A172QQL3
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS02180
gene id: 1652495:ccrud_RS02180
uniprot id: A0A172QR10
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1652495:ccrud RS05525
gene id: 1652495:ccrud_RS05525
uniprot id: A0A172QST3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS03605
gene id: 1652495:ccrud_RS03605
uniprot id: A0A172QRT4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1652495:ccrud RS08795
gene id: 1652495:ccrud_RS08795
uniprot id: A0A172QUG4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1652495:ccrud RS02830
gene id: 1652495:ccrud_RS02830
uniprot id: A0A172QRE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1652495:ccrud RS02890
gene id: 1652495:ccrud_RS02890
uniprot id: A0A172QRH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1652495:ccrud RS07965
gene id: 1652495:ccrud_RS07965
uniprot id: A0A172QU31
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1652495:ccrud RS03370
gene id: 1652495:ccrud_RS03370
uniprot id: A0A172QRP8
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS01460
gene id: 1652495:ccrud_RS01460
uniprot id: A0A172QQR3
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS02410
gene id: 1652495:ccrud_RS02410
uniprot id: A0A172QR59
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS02705
gene id: 1652495:ccrud_RS02705
uniprot id: A0A172QRB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1652495:ccrud RS10275
gene id: 1652495:ccrud_RS10275
uniprot id: A0A172QV76
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1652495:ccrud RS07760
gene id: 1652495:ccrud_RS07760
uniprot id: A0A172QTT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1652495:ccrud RS10090
gene id: 1652495:ccrud_RS10090
uniprot id: A0A172QUZ3
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS10415
gene id: 1652495:ccrud_RS10415
uniprot id: A0A172QV36
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1652495:ccrud RS01225
gene id: 1652495:ccrud_RS01225
uniprot id: A0A172QX48
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS11370
gene id: 1652495:ccrud_RS11370
uniprot id: A0A172QVK5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1652495:ccrud RS06065
gene id: 1652495:ccrud_RS06065
uniprot id: A0A172QT45
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1652495:ccrud RS11605
gene id: 1652495:ccrud_RS11605
uniprot id: A0A172QVP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1652495:ccrud RS12340
gene id: 1652495:ccrud_RS12340
uniprot id: A0A172QW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS02590
gene id: 1652495:ccrud_RS02590
uniprot id: A0A172QR89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1652495:ccrud RS09940
gene id: 1652495:ccrud_RS09940
uniprot id: A0A172QV18
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1652495:ccrud RS10320
gene id: 1652495:ccrud_RS10320
uniprot id: A0A172QV72
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1652495:ccrud RS11510
gene id: 1652495:ccrud_RS11510
uniprot id: A0A172QVM6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1652495:ccrud RS09075
gene id: 1652495:ccrud_RS09075
uniprot id: A0A172QUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1652495:ccrud RS02200
gene id: 1652495:ccrud_RS02200
uniprot id: A0A172QR12
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1652495:ccrud RS13485
gene id: 1652495:ccrud_RS13485
uniprot id: A0A172QWM9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1652495:ccrud RS11985
gene id: 1652495:ccrud_RS11985
uniprot id: A0A172QVV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS11045
gene id: 1652495:ccrud_RS11045
uniprot id: A0A172QVM8
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1652495:ccrud RS07830
gene id: 1652495:ccrud_RS07830
uniprot id: A0A172QTY2
names: Similarity
messages: Belongs to the peptidase M24B family.

1652495:ccrud RS02510
gene id: 1652495:ccrud_RS02510
uniprot id: A0A172QRA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1652495:ccrud RS00285
gene id: 1652495:ccrud_RS00285
uniprot id: A0A172QQ62
names: Similarity
messages: Belongs to the CsoR family.

1652495:ccrud RS00015
gene id: 1652495:ccrud_RS00015
uniprot id: A0A172QQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1652495:ccrud RS02505
gene id: 1652495:ccrud_RS02505
uniprot id: A0A172QR80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1652495:ccrud RS04595
gene id: 1652495:ccrud_RS04595
uniprot id: A0A172QS84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS03400
gene id: 1652495:ccrud_RS03400
uniprot id: A0A172QRM7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1652495:ccrud RS13575
gene id: 1652495:ccrud_RS13575
uniprot id: A0A172QWN2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1652495:ccrud RS11900
gene id: 1652495:ccrud_RS11900
uniprot id: A0A172QVU2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS01275
gene id: 1652495:ccrud_RS01275
uniprot id: A0A172QQP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1652495:ccrud RS01715
gene id: 1652495:ccrud_RS01715
uniprot id: A0A172QQT4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1652495:ccrud RS11690
gene id: 1652495:ccrud_RS11690
uniprot id: A0A172QVX4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1652495:ccrud RS06615
gene id: 1652495:ccrud_RS06615
uniprot id: A0A172QT88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1652495:ccrud RS14565
gene id: 1652495:ccrud_RS14565
uniprot id: A0A172QXY6
names: Function
messages: Involved in the transposition of the insertion sequence.

1652495:ccrud RS11600
gene id: 1652495:ccrud_RS11600
uniprot id: A0A172QVU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1652495:ccrud RS09900
gene id: 1652495:ccrud_RS09900
uniprot id: A0A172QV11
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1652495:ccrud RS05870
gene id: 1652495:ccrud_RS05870
uniprot id: A0A172QSW0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1652495:ccrud RS10885
gene id: 1652495:ccrud_RS10885
uniprot id: A0A172QVK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1652495:ccrud RS12950
gene id: 1652495:ccrud_RS12950
uniprot id: A0A172QWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS13825
gene id: 1652495:ccrud_RS13825
uniprot id: A0A172QX12
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03320
gene id: 1652495:ccrud_RS03320
uniprot id: A0A172QRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1652495:ccrud RS07705
gene id: 1652495:ccrud_RS07705
uniprot id: A0A172QTS8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1652495:ccrud RS05710
gene id: 1652495:ccrud_RS05710
uniprot id: A0A172QSQ8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1652495:ccrud RS03895
gene id: 1652495:ccrud_RS03895
uniprot id: A0A172QRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1652495:ccrud RS08450
gene id: 1652495:ccrud_RS08450
uniprot id: A0A172QUB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1652495:ccrud RS11715
gene id: 1652495:ccrud_RS11715
uniprot id: A0A172QVN9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1652495:ccrud RS11685
gene id: 1652495:ccrud_RS11685
uniprot id: A0A172QVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1652495:ccrud RS05340
gene id: 1652495:ccrud_RS05340
uniprot id: A0A172QSM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1652495:ccrud RS06095
gene id: 1652495:ccrud_RS06095
uniprot id: A0A172QT17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS13580
gene id: 1652495:ccrud_RS13580
uniprot id: A0A172QWV8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1652495:ccrud RS02760
gene id: 1652495:ccrud_RS02760
uniprot id: A0A172QRB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1652495:ccrud RS10145
gene id: 1652495:ccrud_RS10145
uniprot id: A0A172QV02
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1652495:ccrud RS05155
gene id: 1652495:ccrud_RS05155
uniprot id: A0A172QSL1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1652495:ccrud RS08305
gene id: 1652495:ccrud_RS08305
uniprot id: A0A172QU32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1652495:ccrud RS08810
gene id: 1652495:ccrud_RS08810
uniprot id: A0A172QUB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1652495:ccrud RS04020
gene id: 1652495:ccrud_RS04020
uniprot id: A0A172QS12
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1652495:ccrud RS00505
gene id: 1652495:ccrud_RS00505
uniprot id: A0A172QQ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1652495:ccrud RS10680
gene id: 1652495:ccrud_RS10680
uniprot id: A0A172QV98
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1652495:ccrud RS07720
gene id: 1652495:ccrud_RS07720
uniprot id: A0A172QTR6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1652495:ccrud RS12670
gene id: 1652495:ccrud_RS12670
uniprot id: A0A172QW76
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1652495:ccrud RS10075
gene id: 1652495:ccrud_RS10075
uniprot id: A0A172QV37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1652495:ccrud RS08835
gene id: 1652495:ccrud_RS08835
uniprot id: A0A172QUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1652495:ccrud RS13155
gene id: 1652495:ccrud_RS13155
uniprot id: A0A172QWM0
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1652495:ccrud RS06070
gene id: 1652495:ccrud_RS06070
uniprot id: A0A172QSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Membrane

1652495:ccrud RS02600
gene id: 1652495:ccrud_RS02600
uniprot id: A0A172QX09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1652495:ccrud RS00325
gene id: 1652495:ccrud_RS00325
uniprot id: A0A172QQ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1652495:ccrud RS04995
gene id: 1652495:ccrud_RS04995
uniprot id: A0A172QSI8
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07650
gene id: 1652495:ccrud_RS07650
uniprot id: A0A172QTW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS13265
gene id: 1652495:ccrud_RS13265
uniprot id: A0A172QWP0
names: Similarity
messages: Belongs to the pyruvate kinase family.

1652495:ccrud RS09560
gene id: 1652495:ccrud_RS09560
uniprot id: A0A172QUV4
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

1652495:ccrud RS04360
gene id: 1652495:ccrud_RS04360
uniprot id: A0A172QS67
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1652495:ccrud RS06120
gene id: 1652495:ccrud_RS06120
uniprot id: A0A172QSZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS11770
gene id: 1652495:ccrud_RS11770
uniprot id: A0A172QVS2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS00630
gene id: 1652495:ccrud_RS00630
uniprot id: A0A172QQA3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1652495:ccrud RS00095
gene id: 1652495:ccrud_RS00095
uniprot id: A0A172QQ42
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1652495:ccrud RS11760
gene id: 1652495:ccrud_RS11760
uniprot id: A0A172QVR8
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08690
gene id: 1652495:ccrud_RS08690
uniprot id: A0A172QUA2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1652495:ccrud RS03840
gene id: 1652495:ccrud_RS03840
uniprot id: A0A172QRX3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1652495:ccrud RS00340
gene id: 1652495:ccrud_RS00340
uniprot id: A0A172QQ67
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03030
gene id: 1652495:ccrud_RS03030
uniprot id: A0A172QRG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1652495:ccrud RS04780
gene id: 1652495:ccrud_RS04780
uniprot id: A0A172QSD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1652495:ccrud RS13630
gene id: 1652495:ccrud_RS13630
uniprot id: A0A172QWP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS13150
gene id: 1652495:ccrud_RS13150
uniprot id: A0A172QWP4
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1652495:ccrud RS06775
gene id: 1652495:ccrud_RS06775
uniprot id: A0A172QTC7
names: Similarity
messages: Belongs to the TlyA family.

1652495:ccrud RS04285
gene id: 1652495:ccrud_RS04285
uniprot id: A0A172QS63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1652495:ccrud RS12020
gene id: 1652495:ccrud_RS12020
uniprot id: A0A172QVX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

1652495:ccrud RS02450
gene id: 1652495:ccrud_RS02450
uniprot id: A0A172QR61
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1652495:ccrud RS00530
gene id: 1652495:ccrud_RS00530
uniprot id: A0A172QQ92
names: Similarity
messages: Belongs to the cytochrome P450 family.

1652495:ccrud RS09385
gene id: 1652495:ccrud_RS09385
uniprot id: A0A172QUJ7
names: Similarity
messages: Belongs to the asparaginase 1 family.

1652495:ccrud RS07710
gene id: 1652495:ccrud_RS07710
uniprot id: A0A172QTT7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1652495:ccrud RS07280
gene id: 1652495:ccrud_RS07280
uniprot id: A0A172QTI7
names: Similarity
messages: Belongs to the peptidase M18 family.

1652495:ccrud RS00710
gene id: 1652495:ccrud_RS00710
uniprot id: A0A172QQD3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1652495:ccrud RS00520
gene id: 1652495:ccrud_RS00520
uniprot id: A0A172QQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1652495:ccrud RS03085
gene id: 1652495:ccrud_RS03085
uniprot id: A0A172QRI3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1652495:ccrud RS07260
gene id: 1652495:ccrud_RS07260
uniprot id: A0A172QXF7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1652495:ccrud RS09495
gene id: 1652495:ccrud_RS09495
uniprot id: A0A172QUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1652495:ccrud RS13335
gene id: 1652495:ccrud_RS13335
uniprot id: A0A172QWJ5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1652495:ccrud RS03000
gene id: 1652495:ccrud_RS03000
uniprot id: A0A172QRI0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1652495:ccrud RS01250
gene id: 1652495:ccrud_RS01250
uniprot id: A0A172QQK7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1652495:ccrud RS11415
gene id: 1652495:ccrud_RS11415
uniprot id: A0A172QVL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1652495:ccrud RS01280
gene id: 1652495:ccrud_RS01280
uniprot id: A0A172QQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1652495:ccrud RS02525
gene id: 1652495:ccrud_RS02525
uniprot id: A0A172QR95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1652495:ccrud RS12015
gene id: 1652495:ccrud_RS12015
uniprot id: A0A172QW38
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1652495:ccrud RS13905
gene id: 1652495:ccrud_RS13905
uniprot id: A0A172QX16
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1652495:ccrud RS12110
gene id: 1652495:ccrud_RS12110
uniprot id: A0A172QW40
names: Similarity
messages: Belongs to the pantothenate synthetase family.

1652495:ccrud RS07375
gene id: 1652495:ccrud_RS07375
uniprot id: A0A172QTL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1652495:ccrud RS06445
gene id: 1652495:ccrud_RS06445
uniprot id: A0A172QT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1652495:ccrud RS09800
gene id: 1652495:ccrud_RS09800
uniprot id: A0A172QUT6
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07670
gene id: 1652495:ccrud_RS07670
uniprot id: A0A172QTQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1652495:ccrud RS02380
gene id: 1652495:ccrud_RS02380
uniprot id: A0A172QR82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1652495:ccrud RS12590
gene id: 1652495:ccrud_RS12590
uniprot id: A0A172QW65
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1652495:ccrud RS10325
gene id: 1652495:ccrud_RS10325
uniprot id: A0A172QV30
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1652495:ccrud RS04610
gene id: 1652495:ccrud_RS04610
uniprot id: A0A172QS95
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07465
gene id: 1652495:ccrud_RS07465
uniprot id: A0A172QTM5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1652495:ccrud RS02775
gene id: 1652495:ccrud_RS02775
uniprot id: A0A172QRD8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1652495:ccrud RS02165
gene id: 1652495:ccrud_RS02165
uniprot id: A0A172QX76
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1652495:ccrud RS08155
gene id: 1652495:ccrud_RS08155
uniprot id: A0A172QU30
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1652495:ccrud RS07905
gene id: 1652495:ccrud_RS07905
uniprot id: A0A172QTV2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1652495:ccrud RS07240
gene id: 1652495:ccrud_RS07240
uniprot id: A0A172QTI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1652495:ccrud RS12145
gene id: 1652495:ccrud_RS12145
uniprot id: A0A172QVZ1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1652495:ccrud RS08150
gene id: 1652495:ccrud_RS08150
uniprot id: A0A172QTZ0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1652495:ccrud RS13340
gene id: 1652495:ccrud_RS13340
uniprot id: A0A172QXQ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1652495:ccrud RS02060
gene id: 1652495:ccrud_RS02060
uniprot id: A0A172QR15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1652495:ccrud RS07845
gene id: 1652495:ccrud_RS07845
uniprot id: A0A172QX99
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS07095
gene id: 1652495:ccrud_RS07095
uniprot id: A0A172QTI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1652495:ccrud RS09420
gene id: 1652495:ccrud_RS09420
uniprot id: A0A172QUP7
names: Similarity
messages: Belongs to the YggT family.

1652495:ccrud RS01135
gene id: 1652495:ccrud_RS01135
uniprot id: A0A172QQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1652495:ccrud RS06665
gene id: 1652495:ccrud_RS06665
uniprot id: A0A172QT99
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1652495:ccrud RS03075
gene id: 1652495:ccrud_RS03075
uniprot id: A0A172QRI6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1652495:ccrud RS03985
gene id: 1652495:ccrud_RS03985
uniprot id: A0A172QRZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1652495:ccrud RS00365
gene id: 1652495:ccrud_RS00365
uniprot id: A0A172QQ68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS01830
gene id: 1652495:ccrud_RS01830
uniprot id: A0A172QQV9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1652495:ccrud RS10515
gene id: 1652495:ccrud_RS10515
uniprot id: A0A172QV56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1652495:ccrud RS10925
gene id: 1652495:ccrud_RS10925
uniprot id: A0A172QVL1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1652495:ccrud RS05400
gene id: 1652495:ccrud_RS05400
uniprot id: A0A172QXC7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS09810
gene id: 1652495:ccrud_RS09810
uniprot id: A0A172QUU2
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1652495:ccrud RS09520
gene id: 1652495:ccrud_RS09520
uniprot id: A0A172QUP1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1652495:ccrud RS11580
gene id: 1652495:ccrud_RS11580
uniprot id: A0A172QVM7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1652495:ccrud RS06110
gene id: 1652495:ccrud_RS06110
uniprot id: A0A172QSY3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1652495:ccrud RS10700
gene id: 1652495:ccrud_RS10700
uniprot id: A0A172QVE9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1652495:ccrud RS07825
gene id: 1652495:ccrud_RS07825
uniprot id: A0A172QTT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1652495:ccrud RS01245
gene id: 1652495:ccrud_RS01245
uniprot id: A0A172QQK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1652495:ccrud RS03190
gene id: 1652495:ccrud_RS03190
uniprot id: A0A172QRJ5
names: Similarity
messages: Belongs to the DNA photolyase family.

1652495:ccrud RS08640
gene id: 1652495:ccrud_RS08640
uniprot id: A0A172QU92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1652495:ccrud RS14625
gene id: 1652495:ccrud_RS14625
uniprot id: A0A172QY53
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1652495:ccrud RS04350
gene id: 1652495:ccrud_RS04350
uniprot id: A0A172QS44
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1652495:ccrud RS14710
gene id: 1652495:ccrud_RS14710
uniprot id: A0A172QXY5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1652495:ccrud RS03570
gene id: 1652495:ccrud_RS03570
uniprot id: A0A172QRS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS09725
gene id: 1652495:ccrud_RS09725
uniprot id: A0A172QUX9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1652495:ccrud RS05390
gene id: 1652495:ccrud_RS05390
uniprot id: A0A172QSM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1652495:ccrud RS00695
gene id: 1652495:ccrud_RS00695
uniprot id: A0A172QQB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS00635
gene id: 1652495:ccrud_RS00635
uniprot id: A0A172QWX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1652495:ccrud RS05495
gene id: 1652495:ccrud_RS05495
uniprot id: A0A172QSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1652495:ccrud RS10210
gene id: 1652495:ccrud_RS10210
uniprot id: A0A172QV50
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1652495:ccrud RS00975
gene id: 1652495:ccrud_RS00975
uniprot id: A0A172QQH9
names: Similarity
messages: Belongs to the glutamate synthase family.

1652495:ccrud RS10305
gene id: 1652495:ccrud_RS10305
uniprot id: A0A172QV19
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS05680
gene id: 1652495:ccrud_RS05680
uniprot id: A0A172QST0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1652495:ccrud RS07850
gene id: 1652495:ccrud_RS07850
uniprot id: A0A172QU08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1652495:ccrud RS04280
gene id: 1652495:ccrud_RS04280
uniprot id: A0A172QS78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1652495:ccrud RS07485
gene id: 1652495:ccrud_RS07485
uniprot id: A0A172QTS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS03485
gene id: 1652495:ccrud_RS03485
uniprot id: A0A172QRT7
names: Similarity
messages: Belongs to the AccD/PCCB family.

1652495:ccrud RS03420
gene id: 1652495:ccrud_RS03420
uniprot id: A0A172QRP0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1652495:ccrud RS09595
gene id: 1652495:ccrud_RS09595
uniprot id: A0A172QUQ1
names: Similarity
messages: Belongs to the peptidase C40 family.

1652495:ccrud RS13545
gene id: 1652495:ccrud_RS13545
uniprot id: A0A172QWW4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1652495:ccrud RS10775
gene id: 1652495:ccrud_RS10775
uniprot id: A0A172QVB0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1652495:ccrud RS13100
gene id: 1652495:ccrud_RS13100
uniprot id: A0A172QWL0
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1652495:ccrud RS11820
gene id: 1652495:ccrud_RS11820
uniprot id: A0A172QXH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1652495:ccrud RS02295
gene id: 1652495:ccrud_RS02295
uniprot id: A0A172QR32
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03005
gene id: 1652495:ccrud_RS03005
uniprot id: A0A172QRI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1652495:ccrud RS12380
gene id: 1652495:ccrud_RS12380
uniprot id: A0A172QW26
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1652495:ccrud RS04205
gene id: 1652495:ccrud_RS04205
uniprot id: A0A172QS25
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1652495:ccrud RS09475
gene id: 1652495:ccrud_RS09475
uniprot id: A0A172QUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1652495:ccrud RS04035
gene id: 1652495:ccrud_RS04035
uniprot id: A0A172QS07
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1652495:ccrud RS04725
gene id: 1652495:ccrud_RS04725
uniprot id: A0A172QSC0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1652495:ccrud RS02460
gene id: 1652495:ccrud_RS02460
uniprot id: A0A172QR62
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1652495:ccrud RS03270
gene id: 1652495:ccrud_RS03270
uniprot id: A0A172QRM2
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1652495:ccrud RS03290
gene id: 1652495:ccrud_RS03290
uniprot id: A0A172QRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1652495:ccrud RS07300
gene id: 1652495:ccrud_RS07300
uniprot id: A0A172QTJ4
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1652495:ccrud RS04665
gene id: 1652495:ccrud_RS04665
uniprot id: A0A172QSA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1652495:ccrud RS02780
gene id: 1652495:ccrud_RS02780
uniprot id: A0A172QRD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1652495:ccrud RS08715
gene id: 1652495:ccrud_RS08715
uniprot id: A0A172QUD3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1652495:ccrud RS05865
gene id: 1652495:ccrud_RS05865
uniprot id: A0A172QSX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1652495:ccrud RS03645
gene id: 1652495:ccrud_RS03645
uniprot id: A0A172QRW7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1652495:ccrud RS08865
gene id: 1652495:ccrud_RS08865
uniprot id: A0A172QUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1652495:ccrud RS04870
gene id: 1652495:ccrud_RS04870
uniprot id: A0A172QSG6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1652495:ccrud RS06490
gene id: 1652495:ccrud_RS06490
uniprot id: A0A172QT91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1652495:ccrud RS13565
gene id: 1652495:ccrud_RS13565
uniprot id: A0A172QWN7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1652495:ccrud RS02950
gene id: 1652495:ccrud_RS02950
uniprot id: A0A172QRH3
names: Similarity
messages: Belongs to the WXG100 family.

1652495:ccrud RS10510
gene id: 1652495:ccrud_RS10510
uniprot id: A0A172QV62
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1652495:ccrud RS01140
gene id: 1652495:ccrud_RS01140
uniprot id: A0A172QQK9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1652495:ccrud RS02640
gene id: 1652495:ccrud_RS02640
uniprot id: A0A172QR97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1652495:ccrud RS01360
gene id: 1652495:ccrud_RS01360
uniprot id: A0A172QQM5
names: Similarity
messages: Belongs to the catalase family.

1652495:ccrud RS02965
gene id: 1652495:ccrud_RS02965
uniprot id: A0A172QRF8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1652495:ccrud RS10890
gene id: 1652495:ccrud_RS10890
uniprot id: A0A172QVJ7
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS06810
gene id: 1652495:ccrud_RS06810
uniprot id: A0A172QTH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1652495:ccrud RS13690
gene id: 1652495:ccrud_RS13690
uniprot id: A0A172QWX7
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

1652495:ccrud RS05960
gene id: 1652495:ccrud_RS05960
uniprot id: A0A172QSW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS10085
gene id: 1652495:ccrud_RS10085
uniprot id: A0A172QUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1652495:ccrud RS05840
gene id: 1652495:ccrud_RS05840
uniprot id: A0A172QSU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1652495:ccrud RS13955
gene id: 1652495:ccrud_RS13955
uniprot id: A0A172QX26
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1652495:ccrud RS04105
gene id: 1652495:ccrud_RS04105
uniprot id: A0A172QS13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1652495:ccrud RS12135
gene id: 1652495:ccrud_RS12135
uniprot id: A0A172QW69
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1652495:ccrud RS03565
gene id: 1652495:ccrud_RS03565
uniprot id: A0A172QRS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS01645
gene id: 1652495:ccrud_RS01645
uniprot id: A0A172QQS4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1652495:ccrud RS06780
gene id: 1652495:ccrud_RS06780
uniprot id: A0A172QTC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS01550
gene id: 1652495:ccrud_RS01550
uniprot id: A0A172QQS5
names: Similarity
messages: Belongs to the GSP E family.

1652495:ccrud RS07775
gene id: 1652495:ccrud_RS07775
uniprot id: A0A172QTS6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1652495:ccrud RS00120
gene id: 1652495:ccrud_RS00120
uniprot id: A0A172QQ40
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS04955
gene id: 1652495:ccrud_RS04955
uniprot id: A0A172QSF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1652495:ccrud RS03505
gene id: 1652495:ccrud_RS03505
uniprot id: A0A172QRR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS06510
gene id: 1652495:ccrud_RS06510
uniprot id: A0A172QT59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS10590
gene id: 1652495:ccrud_RS10590
uniprot id: A0A172QV71
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1652495:ccrud RS03360
gene id: 1652495:ccrud_RS03360
uniprot id: A0A172QRN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1652495:ccrud RS12495
gene id: 1652495:ccrud_RS12495
uniprot id: A0A172QW42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1652495:ccrud RS05545
gene id: 1652495:ccrud_RS05545
uniprot id: A0A172QSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1652495:ccrud RS05875
gene id: 1652495:ccrud_RS05875
uniprot id: A0A172QSY4
names: Similarity
messages: Belongs to the UPF0045 family.

1652495:ccrud RS08770
gene id: 1652495:ccrud_RS08770
uniprot id: A0A172QUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1652495:ccrud RS02235
gene id: 1652495:ccrud_RS02235
uniprot id: A0A172QR20
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1652495:ccrud RS12805
gene id: 1652495:ccrud_RS12805
uniprot id: A0A172QWA5
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS12610
gene id: 1652495:ccrud_RS12610
uniprot id: A0A172QW56
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1652495:ccrud RS04455
gene id: 1652495:ccrud_RS04455
uniprot id: A0A172QS92
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1652495:ccrud RS13065
gene id: 1652495:ccrud_RS13065
uniprot id: A0A172QWE2
names: Similarity
messages: Belongs to the AccD/PCCB family.

1652495:ccrud RS13040
gene id: 1652495:ccrud_RS13040
uniprot id: A0A172QWE7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1652495:ccrud RS12355
gene id: 1652495:ccrud_RS12355
uniprot id: A0A172QWB0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1652495:ccrud RS08705
gene id: 1652495:ccrud_RS08705
uniprot id: A0A172QUA9
names: Similarity
messages: Belongs to the MQO family.

1652495:ccrud RS10460
gene id: 1652495:ccrud_RS10460
uniprot id: A0A172QV48
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1652495:ccrud RS07600
gene id: 1652495:ccrud_RS07600
uniprot id: A0A172QTW1
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS10300
gene id: 1652495:ccrud_RS10300
uniprot id: A0A172QV20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1652495:ccrud RS12075
gene id: 1652495:ccrud_RS12075
uniprot id: A0A172QW58
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

1652495:ccrud RS12370
gene id: 1652495:ccrud_RS12370
uniprot id: A0A172QW24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1652495:ccrud RS01450
gene id: 1652495:ccrud_RS01450
uniprot id: A0A172QQQ9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1652495:ccrud RS08200
gene id: 1652495:ccrud_RS08200
uniprot id: A0A172QU24
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1652495:ccrud RS13390
gene id: 1652495:ccrud_RS13390
uniprot id: A0A172QWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1652495:ccrud RS03475
gene id: 1652495:ccrud_RS03475
uniprot id: A0A172QRR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1652495:ccrud RS01555
gene id: 1652495:ccrud_RS01555
uniprot id: A0A172QQS1
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS10530
gene id: 1652495:ccrud_RS10530
uniprot id: A0A172QVB3
names: Similarity
messages: Belongs to the pirin family.

1652495:ccrud RS13720
gene id: 1652495:ccrud_RS13720
uniprot id: A0A172QWR8
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS02260
gene id: 1652495:ccrud_RS02260
uniprot id: A0A172QR43
names: Subcellular Location Annotation
messages: Cell membrane

1652495:ccrud RS11675
gene id: 1652495:ccrud_RS11675
uniprot id: A0A172QVP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1652495:ccrud RS04400
gene id: 1652495:ccrud_RS04400
uniprot id: A0A172QS79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1652495:ccrud RS11665
gene id: 1652495:ccrud_RS11665
uniprot id: A0A172QVN2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1652495:ccrud RS05425
gene id: 1652495:ccrud_RS05425
uniprot id: A0A172QSK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1652495:ccrud RS08500
gene id: 1652495:ccrud_RS08500
uniprot id: A0A172QU91
names: Similarity
messages: Belongs to the YciI family.

1652495:ccrud RS00005
gene id: 1652495:ccrud_RS00005
uniprot id: A0A172QQ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1652495:ccrud RS13475
gene id: 1652495:ccrud_RS13475
uniprot id: A0A172QWV0
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS04625
gene id: 1652495:ccrud_RS04625
uniprot id: A0A172QSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1652495:ccrud RS11755
gene id: 1652495:ccrud_RS11755
uniprot id: A0A172QVY1
names: Similarity
messages: Belongs to the DSD1 family.

1652495:ccrud RS05775
gene id: 1652495:ccrud_RS05775
uniprot id: A0A172QSW6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1652495:ccrud RS12475
gene id: 1652495:ccrud_RS12475
uniprot id: A0A172QWD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1652495:ccrud RS06450
gene id: 1652495:ccrud_RS06450
uniprot id: A0A172QT92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1652495:ccrud RS03755
gene id: 1652495:ccrud_RS03755
uniprot id: A0A172QRX0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1652495:ccrud RS04890
gene id: 1652495:ccrud_RS04890
uniprot id: A0A172QSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1652495:ccrud RS10015
gene id: 1652495:ccrud_RS10015
uniprot id: A0A172QV32
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1652495:ccrud RS05830
gene id: 1652495:ccrud_RS05830
uniprot id: A0A172QSU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1652495:ccrud RS04225
gene id: 1652495:ccrud_RS04225
uniprot id: A0A172QS43
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS01160
gene id: 1652495:ccrud_RS01160
uniprot id: A0A172QQJ6
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1652495:ccrud RS08565
gene id: 1652495:ccrud_RS08565
uniprot id: A0A172QUD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1652495:ccrud RS02755
gene id: 1652495:ccrud_RS02755
uniprot id: A0A172QRB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1652495:ccrud RS14705
gene id: 1652495:ccrud_RS14705
uniprot id: A0A172QY17
names: Similarity
messages: Belongs to the transposase 7 family.

1652495:ccrud RS10720
gene id: 1652495:ccrud_RS10720
uniprot id: A0A172QVG7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1652495:ccrud RS06700
gene id: 1652495:ccrud_RS06700
uniprot id: A0A172QTD8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1652495:ccrud RS00470
gene id: 1652495:ccrud_RS00470
uniprot id: A0A172QWX0
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1652495:ccrud RS07235
gene id: 1652495:ccrud_RS07235
uniprot id: A0A172QTP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1652495:ccrud RS13405
gene id: 1652495:ccrud_RS13405
uniprot id: A0A172QWL8
names: Similarity
messages: Belongs to the universal stress protein A family.

1652495:ccrud RS04570
gene id: 1652495:ccrud_RS04570
uniprot id: A0A172QSA3
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS05330
gene id: 1652495:ccrud_RS05330
uniprot id: A0A172QSQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1652495:ccrud RS02665
gene id: 1652495:ccrud_RS02665
uniprot id: A0A172QRB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1652495:ccrud RS02095
gene id: 1652495:ccrud_RS02095
uniprot id: A0A172QR16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1652495:ccrud RS09630
gene id: 1652495:ccrud_RS09630
uniprot id: A0A172QUR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1652495:ccrud RS02835
gene id: 1652495:ccrud_RS02835
uniprot id: A0A172QRG5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1652495:ccrud RS12035
gene id: 1652495:ccrud_RS12035
uniprot id: A0A172QVW7
names: Similarity
messages: Belongs to the Nth/MutY family.

1652495:ccrud RS07910
gene id: 1652495:ccrud_RS07910
uniprot id: A0A172QU12
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1652495:ccrud RS12260
gene id: 1652495:ccrud_RS12260
uniprot id: A0A172QVZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1652495:ccrud RS07060
gene id: 1652495:ccrud_RS07060
uniprot id: A0A172QTK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1652495:ccrud RS12655
gene id: 1652495:ccrud_RS12655
uniprot id: A0A172QW80
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1652495:ccrud RS03890
gene id: 1652495:ccrud_RS03890
uniprot id: A0A172QRW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1652495:ccrud RS03095
gene id: 1652495:ccrud_RS03095
uniprot id: A0A172QRJ7
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS05725
gene id: 1652495:ccrud_RS05725
uniprot id: A0A172QSV5
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS02645
gene id: 1652495:ccrud_RS02645
uniprot id: A0A172QRA3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1652495:ccrud RS11730
gene id: 1652495:ccrud_RS11730
uniprot id: A0A172QVX0
names: Similarity
messages: Belongs to the GARS family.

1652495:ccrud RS09910
gene id: 1652495:ccrud_RS09910
uniprot id: A0A172QUV5
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS09585
gene id: 1652495:ccrud_RS09585
uniprot id: A0A172QUP5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1652495:ccrud RS06800
gene id: 1652495:ccrud_RS06800
uniprot id: A0A172QTA9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS03425
gene id: 1652495:ccrud_RS03425
uniprot id: A0A172QRQ8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1652495:ccrud RS11035
gene id: 1652495:ccrud_RS11035
uniprot id: A0A172QVF3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1652495:ccrud RS13410
gene id: 1652495:ccrud_RS13410
uniprot id: A0A172QWU0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1652495:ccrud RS03635
gene id: 1652495:ccrud_RS03635
uniprot id: A0A172QRU9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1652495:ccrud RS14725
gene id: 1652495:ccrud_RS14725
uniprot id: A0A172QXY4
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1652495:ccrud RS11970
gene id: 1652495:ccrud_RS11970
uniprot id: A0A172QVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS07620
gene id: 1652495:ccrud_RS07620
uniprot id: A0A172QTP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1652495:ccrud RS01310
gene id: 1652495:ccrud_RS01310
uniprot id: A0A172QQL8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1652495:ccrud RS12850
gene id: 1652495:ccrud_RS12850
uniprot id: A0A172QWJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1652495:ccrud RS02865
gene id: 1652495:ccrud_RS02865
uniprot id: A0A172QRE4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1652495:ccrud RS11025
gene id: 1652495:ccrud_RS11025
uniprot id: A0A172QVF1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1652495:ccrud RS06550
gene id: 1652495:ccrud_RS06550
uniprot id: A0A172QT78
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS04435
gene id: 1652495:ccrud_RS04435
uniprot id: A0A172QS70
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1652495:ccrud RS12445
gene id: 1652495:ccrud_RS12445
uniprot id: A0A172QW36
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1652495:ccrud RS11860
gene id: 1652495:ccrud_RS11860
uniprot id: A0A172QVT2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1652495:ccrud RS13855
gene id: 1652495:ccrud_RS13855
uniprot id: A0A172QX07
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1652495:ccrud RS05595
gene id: 1652495:ccrud_RS05595
uniprot id: A0A172QSN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS08210
gene id: 1652495:ccrud_RS08210
uniprot id: A0A172QXA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1652495:ccrud RS03535
gene id: 1652495:ccrud_RS03535
uniprot id: A0A172QRU6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1652495:ccrud RS05910
gene id: 1652495:ccrud_RS05910
uniprot id: A0A172QSY0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1652495:ccrud RS02490
gene id: 1652495:ccrud_RS02490
uniprot id: A0A172QR69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1652495:ccrud RS03285
gene id: 1652495:ccrud_RS03285
uniprot id: A0A172QRM9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1652495:ccrud RS11265
gene id: 1652495:ccrud_RS11265
uniprot id: A0A172QXG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1652495:ccrud RS01180
gene id: 1652495:ccrud_RS01180
uniprot id: A0A172QQK5
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS12250
gene id: 1652495:ccrud_RS12250
uniprot id: A0A172QW68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1652495:ccrud RS11805
gene id: 1652495:ccrud_RS11805
uniprot id: A0A172QW07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1652495:ccrud RS02765
gene id: 1652495:ccrud_RS02765
uniprot id: A0A172QRC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1652495:ccrud RS08870
gene id: 1652495:ccrud_RS08870
uniprot id: A0A172QUD9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1652495:ccrud RS09325
gene id: 1652495:ccrud_RS09325
uniprot id: A0A172QUI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1652495:ccrud RS14580
gene id: 1652495:ccrud_RS14580
uniprot id: A0A172QXY4
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1652495:ccrud RS06720
gene id: 1652495:ccrud_RS06720
uniprot id: A0A172QTD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1652495:ccrud RS10615
gene id: 1652495:ccrud_RS10615
uniprot id: A0A172QVE6
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS10675
gene id: 1652495:ccrud_RS10675
uniprot id: A0A172QVF8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1652495:ccrud RS10585
gene id: 1652495:ccrud_RS10585
uniprot id: A0A172QV77
names: Similarity
messages: Belongs to the LOG family.

1652495:ccrud RS00025
gene id: 1652495:ccrud_RS00025
uniprot id: A0A172QQ34
names: Similarity
messages: Belongs to the UPF0232 family.

1652495:ccrud RS10105
gene id: 1652495:ccrud_RS10105
uniprot id: A0A172QUZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1652495:ccrud RS00930
gene id: 1652495:ccrud_RS00930
uniprot id: A0A172QQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1652495:ccrud RS07405
gene id: 1652495:ccrud_RS07405
uniprot id: A0A172QTL5
names: Similarity
messages: Belongs to the UPF0098 family.

1652495:ccrud RS00140
gene id: 1652495:ccrud_RS00140
uniprot id: A0A172QQ29
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS13145
gene id: 1652495:ccrud_RS13145
uniprot id: A0A172QWG9
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1652495:ccrud RS06050
gene id: 1652495:ccrud_RS06050
uniprot id: A0A172QT21
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03735
gene id: 1652495:ccrud_RS03735
uniprot id: A0A172QRU8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1652495:ccrud RS02365
gene id: 1652495:ccrud_RS02365
uniprot id: A0A172QR46
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS01985
gene id: 1652495:ccrud_RS01985
uniprot id: A0A172QQZ5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1652495:ccrud RS12735
gene id: 1652495:ccrud_RS12735
uniprot id: A0A172QWF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1652495:ccrud RS05160
gene id: 1652495:ccrud_RS05160
uniprot id: A0A172QSL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1652495:ccrud RS04705
gene id: 1652495:ccrud_RS04705
uniprot id: A0A172QSC6
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS05850
gene id: 1652495:ccrud_RS05850
uniprot id: A0A172QT08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1652495:ccrud RS09410
gene id: 1652495:ccrud_RS09410
uniprot id: A0A172QUM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1652495:ccrud RS10080
gene id: 1652495:ccrud_RS10080
uniprot id: A0A172QUY2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1652495:ccrud RS08860
gene id: 1652495:ccrud_RS08860
uniprot id: A0A172QUC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1652495:ccrud RS10810
gene id: 1652495:ccrud_RS10810
uniprot id: A0A172QVH4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1652495:ccrud RS03660
gene id: 1652495:ccrud_RS03660
uniprot id: A0A172QRS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1652495:ccrud RS11145
gene id: 1652495:ccrud_RS11145
uniprot id: A0A172QVH3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1652495:ccrud RS03015
gene id: 1652495:ccrud_RS03015
uniprot id: A0A172QRH6
names: Similarity
messages: Belongs to the peptidase S33 family.

1652495:ccrud RS10010
gene id: 1652495:ccrud_RS10010
uniprot id: A0A172QUW3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS00805
gene id: 1652495:ccrud_RS00805
uniprot id: A0A172QQD6
names: Similarity
messages: Belongs to the peptidase M13 family.

1652495:ccrud RS03665
gene id: 1652495:ccrud_RS03665
uniprot id: A0A172QRU5
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1652495:ccrud RS12955
gene id: 1652495:ccrud_RS12955
uniprot id: A0A172QWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS08840
gene id: 1652495:ccrud_RS08840
uniprot id: A0A172QUH8
names: Similarity
messages: Belongs to the DprA/Smf family.

1652495:ccrud RS12105
gene id: 1652495:ccrud_RS12105
uniprot id: A0A172QVZ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS10000
gene id: 1652495:ccrud_RS10000
uniprot id: A0A172QUW8
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1652495:ccrud RS05035
gene id: 1652495:ccrud_RS05035
uniprot id: A0A172QSH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1652495:ccrud RS12615
gene id: 1652495:ccrud_RS12615
uniprot id: A0A172QW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1652495:ccrud RS02660
gene id: 1652495:ccrud_RS02660
uniprot id: A0A172QR96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1652495:ccrud RS02840
gene id: 1652495:ccrud_RS02840
uniprot id: A0A172QRF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1652495:ccrud RS14650
gene id: 1652495:ccrud_RS14650
uniprot id: A0A172QXY5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1652495:ccrud RS08575
gene id: 1652495:ccrud_RS08575
uniprot id: A0A172QUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1652495:ccrud RS01485
gene id: 1652495:ccrud_RS01485
uniprot id: A0A172QQP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1652495:ccrud RS08505
gene id: 1652495:ccrud_RS08505
uniprot id: A0A172QU61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1652495:ccrud RS05220
gene id: 1652495:ccrud_RS05220
uniprot id: A0A172QSM2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08040
gene id: 1652495:ccrud_RS08040
uniprot id: A0A172QU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1652495:ccrud RS13585
gene id: 1652495:ccrud_RS13585
uniprot id: A0A172QWP2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03725
gene id: 1652495:ccrud_RS03725
uniprot id: A0A172QRU7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1652495:ccrud RS10620
gene id: 1652495:ccrud_RS10620
uniprot id: A0A172QVE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS09705
gene id: 1652495:ccrud_RS09705
uniprot id: A0A172QUR5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1652495:ccrud RS03435
gene id: 1652495:ccrud_RS03435
uniprot id: A0A172QRS7
names: Similarity
messages: Belongs to the PrpD family.

1652495:ccrud RS01945
gene id: 1652495:ccrud_RS01945
uniprot id: A0A172QQZ9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1652495:ccrud RS11345
gene id: 1652495:ccrud_RS11345
uniprot id: A0A172QVK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1652495:ccrud RS12935
gene id: 1652495:ccrud_RS12935
uniprot id: A0A172QWC5
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

1652495:ccrud RS08320
gene id: 1652495:ccrud_RS08320
uniprot id: A0A172QU60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1652495:ccrud RS02415
gene id: 1652495:ccrud_RS02415
uniprot id: A0A172QR54
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1652495:ccrud RS01670
gene id: 1652495:ccrud_RS01670
uniprot id: A0A172QQU2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS09285
gene id: 1652495:ccrud_RS09285
uniprot id: A0A172QUN7
names: Similarity
messages: Belongs to the HSP15 family.

1652495:ccrud RS13880
gene id: 1652495:ccrud_RS13880
uniprot id: A0A172QX03
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1652495:ccrud RS12725
gene id: 1652495:ccrud_RS12725
uniprot id: A0A172QW83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS05980
gene id: 1652495:ccrud_RS05980
uniprot id: A0A172QSX5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1652495:ccrud RS10020
gene id: 1652495:ccrud_RS10020
uniprot id: A0A172QV29
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

1652495:ccrud RS01355
gene id: 1652495:ccrud_RS01355
uniprot id: A0A172QQN0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1652495:ccrud RS08085
gene id: 1652495:ccrud_RS08085
uniprot id: A0A172QU43
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS14600
gene id: 1652495:ccrud_RS14600
uniprot id: A0A172QY38
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1652495:ccrud RS12870
gene id: 1652495:ccrud_RS12870
uniprot id: A0A172QWH2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS10390
gene id: 1652495:ccrud_RS10390
uniprot id: A0A172QV97
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1652495:ccrud RS08635
gene id: 1652495:ccrud_RS08635
uniprot id: A0A172QUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1652495:ccrud RS06955
gene id: 1652495:ccrud_RS06955
uniprot id: A0A172QTF6
names: Similarity
messages: Belongs to the UPF0225 family.

1652495:ccrud RS12900
gene id: 1652495:ccrud_RS12900
uniprot id: A0A172QWI3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1652495:ccrud RS08510
gene id: 1652495:ccrud_RS08510
uniprot id: A0A172QUC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

1652495:ccrud RS04290
gene id: 1652495:ccrud_RS04290
uniprot id: A0A172QS60
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1652495:ccrud RS06555
gene id: 1652495:ccrud_RS06555
uniprot id: A0A172QTA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1652495:ccrud RS08030
gene id: 1652495:ccrud_RS08030
uniprot id: A0A172QU33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1652495:ccrud RS11850
gene id: 1652495:ccrud_RS11850
uniprot id: A0A172QVT1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1652495:ccrud RS11105
gene id: 1652495:ccrud_RS11105
uniprot id: A0A172QVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1652495:ccrud RS09720
gene id: 1652495:ccrud_RS09720
uniprot id: A0A172QUS5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1652495:ccrud RS11380
gene id: 1652495:ccrud_RS11380
uniprot id: A0A172QVR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1652495:ccrud RS08995
gene id: 1652495:ccrud_RS08995
uniprot id: A0A172QUF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS00500
gene id: 1652495:ccrud_RS00500
uniprot id: A0A172QQA8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1652495:ccrud RS01130
gene id: 1652495:ccrud_RS01130
uniprot id: A0A172QQJ9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1652495:ccrud RS00515
gene id: 1652495:ccrud_RS00515
uniprot id: A0A172QQ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1652495:ccrud RS02955
gene id: 1652495:ccrud_RS02955
uniprot id: A0A172QRH4
names: Similarity
messages: Belongs to the WXG100 family.

1652495:ccrud RS04375
gene id: 1652495:ccrud_RS04375
uniprot id: A0A172QS61
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08225
gene id: 1652495:ccrud_RS08225
uniprot id: A0A172QU67
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1652495:ccrud RS01950
gene id: 1652495:ccrud_RS01950
uniprot id: A0A172QQY5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1652495:ccrud RS14545
gene id: 1652495:ccrud_RS14545
uniprot id: A0A172QXW1
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1652495:ccrud RS07785
gene id: 1652495:ccrud_RS07785
uniprot id: A0A172QTT3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1652495:ccrud RS03060
gene id: 1652495:ccrud_RS03060
uniprot id: A0A172QRJ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1652495:ccrud RS03375
gene id: 1652495:ccrud_RS03375
uniprot id: A0A172QRN9
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS02885
gene id: 1652495:ccrud_RS02885
uniprot id: A0A172QRF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1652495:ccrud RS13915
gene id: 1652495:ccrud_RS13915
uniprot id: A0A172QX30
names: Similarity
messages: Belongs to the thioredoxin family.

1652495:ccrud RS11610
gene id: 1652495:ccrud_RS11610
uniprot id: A0A172QVM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1652495:ccrud RS02190
gene id: 1652495:ccrud_RS02190
uniprot id: A0A172QR13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1652495:ccrud RS02425
gene id: 1652495:ccrud_RS02425
uniprot id: A0A172QR73
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1652495:ccrud RS00490
gene id: 1652495:ccrud_RS00490
uniprot id: A0A172QQA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1652495:ccrud RS02430
gene id: 1652495:ccrud_RS02430
uniprot id: A0A172QR94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1652495:ccrud RS12030
gene id: 1652495:ccrud_RS12030
uniprot id: A0A172QW28
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1652495:ccrud RS05135
gene id: 1652495:ccrud_RS05135
uniprot id: A0A172QSM4
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS05790
gene id: 1652495:ccrud_RS05790
uniprot id: A0A172QST8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS06310
gene id: 1652495:ccrud_RS06310
uniprot id: A0A172QT69
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1652495:ccrud RS13055
gene id: 1652495:ccrud_RS13055
uniprot id: A0A172QWE9
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS00625
gene id: 1652495:ccrud_RS00625
uniprot id: A0A172QQA5
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1652495:ccrud RS05365
gene id: 1652495:ccrud_RS05365
uniprot id: A0A172QSK0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1652495:ccrud RS06605
gene id: 1652495:ccrud_RS06605
uniprot id: A0A172QT93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1652495:ccrud RS06420
gene id: 1652495:ccrud_RS06420
uniprot id: A0A172QTA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1652495:ccrud RS09655
gene id: 1652495:ccrud_RS09655
uniprot id: A0A172QUP9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1652495:ccrud RS08735
gene id: 1652495:ccrud_RS08735
uniprot id: A0A172QUF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1652495:ccrud RS04635
gene id: 1652495:ccrud_RS04635
uniprot id: A0A172QSB6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1652495:ccrud RS03690
gene id: 1652495:ccrud_RS03690
uniprot id: A0A172QRV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1652495:ccrud RS07100
gene id: 1652495:ccrud_RS07100
uniprot id: A0A172QX84
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1652495:ccrud RS13305
gene id: 1652495:ccrud_RS13305
uniprot id: A0A172QWJ9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1652495:ccrud RS10690
gene id: 1652495:ccrud_RS10690
uniprot id: A0A172QVA3
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1652495:ccrud RS01730
gene id: 1652495:ccrud_RS01730
uniprot id: A0A172QQV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Membrane

1652495:ccrud RS06595
gene id: 1652495:ccrud_RS06595
uniprot id: A0A172QTB8
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03145
gene id: 1652495:ccrud_RS03145
uniprot id: A0A172QRJ3
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS02530
gene id: 1652495:ccrud_RS02530
uniprot id: A0A172QR76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1652495:ccrud RS02820
gene id: 1652495:ccrud_RS02820
uniprot id: A0A172QRC4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1652495:ccrud RS03775
gene id: 1652495:ccrud_RS03775
uniprot id: A0A172QRV5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1652495:ccrud RS07690
gene id: 1652495:ccrud_RS07690
uniprot id: A0A172QTR2
names: Caution
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS00255
gene id: 1652495:ccrud_RS00255
uniprot id: A0A172QQ60
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1652495:ccrud RS01400
gene id: 1652495:ccrud_RS01400
uniprot id: A0A172QQQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1652495:ccrud RS08555
gene id: 1652495:ccrud_RS08555
uniprot id: A0A172QU97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1652495:ccrud RS13590
gene id: 1652495:ccrud_RS13590
uniprot id: A0A172QWW9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1652495:ccrud RS11795
gene id: 1652495:ccrud_RS11795
uniprot id: A0A172QVT3
names: Similarity
messages: Belongs to the YciI family.

1652495:ccrud RS11680
gene id: 1652495:ccrud_RS11680
uniprot id: A0A172QVV9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1652495:ccrud RS07780
gene id: 1652495:ccrud_RS07780
uniprot id: A0A172QTX2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS09550
gene id: 1652495:ccrud_RS09550
uniprot id: A0A172QUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1652495:ccrud RS08970
gene id: 1652495:ccrud_RS08970
uniprot id: A0A172QUD0
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS05410
gene id: 1652495:ccrud_RS05410
uniprot id: A0A172QSQ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1652495:ccrud RS05360
gene id: 1652495:ccrud_RS05360
uniprot id: A0A172QSQ4
names: Similarity
messages: Belongs to the LOG family.

1652495:ccrud RS13705
gene id: 1652495:ccrud_RS13705
uniprot id: A0A172QWR9
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

1652495:ccrud RS14665
gene id: 1652495:ccrud_RS14665
uniprot id: A0A172QXY4
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1652495:ccrud RS07130
gene id: 1652495:ccrud_RS07130
uniprot id: A0A172QTL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

1652495:ccrud RS06315
gene id: 1652495:ccrud_RS06315
uniprot id: A0A172QT87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1652495:ccrud RS03885
gene id: 1652495:ccrud_RS03885
uniprot id: A0A172QRY8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1652495:ccrud RS10785
gene id: 1652495:ccrud_RS10785
uniprot id: A0A172QVH7
names: Similarity
messages: Belongs to the peptidase M1 family.

1652495:ccrud RS07085
gene id: 1652495:ccrud_RS07085
uniprot id: A0A172QXG0
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1652495:ccrud RS04935
gene id: 1652495:ccrud_RS04935
uniprot id: A0A172QSE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1652495:ccrud RS10710
gene id: 1652495:ccrud_RS10710
uniprot id: A0A172QVG5
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1652495:ccrud RS02070
gene id: 1652495:ccrud_RS02070
uniprot id: A0A172QQZ0
names: Similarity
messages: Belongs to the CsoR family.

1652495:ccrud RS11295
gene id: 1652495:ccrud_RS11295
uniprot id: A0A172QVJ4
names: Similarity
messages: Belongs to the peptidase S58 family.

1652495:ccrud RS03155
gene id: 1652495:ccrud_RS03155
uniprot id: A0A172QRK7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1652495:ccrud RS06090
gene id: 1652495:ccrud_RS06090
uniprot id: A0A172QSZ7
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08960
gene id: 1652495:ccrud_RS08960
uniprot id: A0A172QUK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1652495:ccrud RS15280
gene id: 1652495:ccrud_RS15280
uniprot id: A0A172QXZ5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1652495:ccrud RS09195
gene id: 1652495:ccrud_RS09195
uniprot id: A0A172QUI0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1652495:ccrud RS09010
gene id: 1652495:ccrud_RS09010
uniprot id: A0A172QUE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1652495:ccrud RS09635
gene id: 1652495:ccrud_RS09635
uniprot id: A0A172QUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1652495:ccrud RS13550
gene id: 1652495:ccrud_RS13550
uniprot id: A0A172QWU3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1652495:ccrud RS07075
gene id: 1652495:ccrud_RS07075
uniprot id: A0A172QTH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS07575
gene id: 1652495:ccrud_RS07575
uniprot id: A0A172QTP5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1652495:ccrud RS07450
gene id: 1652495:ccrud_RS07450
uniprot id: A0A172QTP8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1652495:ccrud RS04605
gene id: 1652495:ccrud_RS04605
uniprot id: A0A172QSA1
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07635
gene id: 1652495:ccrud_RS07635
uniprot id: A0A172QTW8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1652495:ccrud RS12865
gene id: 1652495:ccrud_RS12865
uniprot id: A0A172QWK0
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1652495:ccrud RS05565
gene id: 1652495:ccrud_RS05565
uniprot id: A0A172QSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1652495:ccrud RS05890
gene id: 1652495:ccrud_RS05890
uniprot id: A0A172QSV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1652495:ccrud RS00495
gene id: 1652495:ccrud_RS00495
uniprot id: A0A172QQA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1652495:ccrud RS11615
gene id: 1652495:ccrud_RS11615
uniprot id: A0A172QVP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1652495:ccrud RS07115
gene id: 1652495:ccrud_RS07115
uniprot id: A0A172QTG1
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS14645
gene id: 1652495:ccrud_RS14645
uniprot id: A0A172QY17
names: Similarity
messages: Belongs to the transposase 7 family.

1652495:ccrud RS01200
gene id: 1652495:ccrud_RS01200
uniprot id: A0A172QQN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1652495:ccrud RS03520
gene id: 1652495:ccrud_RS03520
uniprot id: A0A172QRR0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1652495:ccrud RS08990
gene id: 1652495:ccrud_RS08990
uniprot id: A0A172QUE7
names: Similarity
messages: Belongs to the P(II) protein family.

1652495:ccrud RS06425
gene id: 1652495:ccrud_RS06425
uniprot id: A0A172QT63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1652495:ccrud RS05920
gene id: 1652495:ccrud_RS05920
uniprot id: A0A172QSY9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1652495:ccrud RS08550
gene id: 1652495:ccrud_RS08550
uniprot id: A0A172QU58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1652495:ccrud RS05995
gene id: 1652495:ccrud_RS05995
uniprot id: A0A172QT10
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1652495:ccrud RS00020
gene id: 1652495:ccrud_RS00020
uniprot id: A0A172QQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1652495:ccrud RS12160
gene id: 1652495:ccrud_RS12160
uniprot id: A0A172QVY2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1652495:ccrud RS03330
gene id: 1652495:ccrud_RS03330
uniprot id: A0A172QRQ5
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS09470
gene id: 1652495:ccrud_RS09470
uniprot id: A0A172QUM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS10120
gene id: 1652495:ccrud_RS10120
uniprot id: A0A172QV54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1652495:ccrud RS07685
gene id: 1652495:ccrud_RS07685
uniprot id: A0A172QTX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1652495:ccrud RS07660
gene id: 1652495:ccrud_RS07660
uniprot id: A0A172QTS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1652495:ccrud RS09365
gene id: 1652495:ccrud_RS09365
uniprot id: A0A172QUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1652495:ccrud RS04505
gene id: 1652495:ccrud_RS04505
uniprot id: A0A172QS99
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1652495:ccrud RS02690
gene id: 1652495:ccrud_RS02690
uniprot id: A0A172QRA7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1652495:ccrud RS07655
gene id: 1652495:ccrud_RS07655
uniprot id: A0A172QTR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1652495:ccrud RS02055
gene id: 1652495:ccrud_RS02055
uniprot id: A0A172QR27
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1652495:ccrud RS05885
gene id: 1652495:ccrud_RS05885
uniprot id: A0A172QT14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1652495:ccrud RS05745
gene id: 1652495:ccrud_RS05745
uniprot id: A0A172QSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1652495:ccrud RS09660
gene id: 1652495:ccrud_RS09660
uniprot id: A0A172QUX2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1652495:ccrud RS09435
gene id: 1652495:ccrud_RS09435
uniprot id: A0A172QUK9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1652495:ccrud RS11590
gene id: 1652495:ccrud_RS11590
uniprot id: A0A172QVN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1652495:ccrud RS05705
gene id: 1652495:ccrud_RS05705
uniprot id: A0A172QSU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1652495:ccrud RS08875
gene id: 1652495:ccrud_RS08875
uniprot id: A0A172QUB7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS01065
gene id: 1652495:ccrud_RS01065
uniprot id: A0A172QQJ0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1652495:ccrud RS11950
gene id: 1652495:ccrud_RS11950
uniprot id: A0A172QVV1
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1652495:ccrud RS06635
gene id: 1652495:ccrud_RS06635
uniprot id: A0A172QT79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS04645
gene id: 1652495:ccrud_RS04645
uniprot id: A0A172QX39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1652495:ccrud RS08195
gene id: 1652495:ccrud_RS08195
uniprot id: A0A172QU13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1652495:ccrud RS10255
gene id: 1652495:ccrud_RS10255
uniprot id: A0A172QV14
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS05345
gene id: 1652495:ccrud_RS05345
uniprot id: A0A172QSQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1652495:ccrud RS05575
gene id: 1652495:ccrud_RS05575
uniprot id: A0A172QSR3
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1652495:ccrud RS10110
gene id: 1652495:ccrud_RS10110
uniprot id: A0A172QV49
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1652495:ccrud RS08360
gene id: 1652495:ccrud_RS08360
uniprot id: A0A172QU41
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1652495:ccrud RS04275
gene id: 1652495:ccrud_RS04275
uniprot id: A0A172QS51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1652495:ccrud RS11505
gene id: 1652495:ccrud_RS11505
uniprot id: A0A172QVU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS09360
gene id: 1652495:ccrud_RS09360
uniprot id: A0A172QUL5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1652495:ccrud RS07180
gene id: 1652495:ccrud_RS07180
uniprot id: A0A172QTN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS09415
gene id: 1652495:ccrud_RS09415
uniprot id: A0A172QUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1652495:ccrud RS13805
gene id: 1652495:ccrud_RS13805
uniprot id: A0A172QWZ4
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS04650
gene id: 1652495:ccrud_RS04650
uniprot id: A0A172QS94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1652495:ccrud RS01510
gene id: 1652495:ccrud_RS01510
uniprot id: A0A172QQS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1652495:ccrud RS09190
gene id: 1652495:ccrud_RS09190
uniprot id: A0A172QUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1652495:ccrud RS05015
gene id: 1652495:ccrud_RS05015
uniprot id: A0A172QSH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1652495:ccrud RS07035
gene id: 1652495:ccrud_RS07035
uniprot id: A0A172QTF3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1652495:ccrud RS10960
gene id: 1652495:ccrud_RS10960
uniprot id: A0A172QVE0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1652495:ccrud RS07725
gene id: 1652495:ccrud_RS07725
uniprot id: A0A172QTW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1652495:ccrud RS10360
gene id: 1652495:ccrud_RS10360
uniprot id: A0A172QV27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1652495:ccrud RS09305
gene id: 1652495:ccrud_RS09305
uniprot id: A0A172QUJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1652495:ccrud RS06690
gene id: 1652495:ccrud_RS06690
uniprot id: A0A172QTF2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1652495:ccrud RS09880
gene id: 1652495:ccrud_RS09880
uniprot id: A0A172QUU8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1652495:ccrud RS09295
gene id: 1652495:ccrud_RS09295
uniprot id: A0A172QUJ8
names: Similarity
messages: Belongs to the IMPACT family.

1652495:ccrud RS01100
gene id: 1652495:ccrud_RS01100
uniprot id: A0A172QQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS07680
gene id: 1652495:ccrud_RS07680
uniprot id: A0A172QTR3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1652495:ccrud RS05570
gene id: 1652495:ccrud_RS05570
uniprot id: A0A172QSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1652495:ccrud RS09070
gene id: 1652495:ccrud_RS09070
uniprot id: A0A172QUF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1652495:ccrud RS03835
gene id: 1652495:ccrud_RS03835
uniprot id: A0A172QRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1652495:ccrud RS00350
gene id: 1652495:ccrud_RS00350
uniprot id: A0A172QQ83
names: Subcellular Location Annotation
messages: Cytoplasm

1652495:ccrud RS10910
gene id: 1652495:ccrud_RS10910
uniprot id: A0A172QVD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS04255
gene id: 1652495:ccrud_RS04255
uniprot id: A0A172QS35
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1652495:ccrud RS05820
gene id: 1652495:ccrud_RS05820
uniprot id: A0A172QSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1652495:ccrud RS05810
gene id: 1652495:ccrud_RS05810
uniprot id: A0A172QST1
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03720
gene id: 1652495:ccrud_RS03720
uniprot id: A0A172QRV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1652495:ccrud RS07740
gene id: 1652495:ccrud_RS07740
uniprot id: A0A172QTS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1652495:ccrud RS09000
gene id: 1652495:ccrud_RS09000
uniprot id: A0A172QUD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1652495:ccrud RS09760
gene id: 1652495:ccrud_RS09760
uniprot id: A0A172QUS4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1652495:ccrud RS12540
gene id: 1652495:ccrud_RS12540
uniprot id: A0A172QW59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1652495:ccrud RS03740
gene id: 1652495:ccrud_RS03740
uniprot id: A0A172QRW9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1652495:ccrud RS13090
gene id: 1652495:ccrud_RS13090
uniprot id: A0A172QWF8
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

1652495:ccrud RS08455
gene id: 1652495:ccrud_RS08455
uniprot id: A0A172QU38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1652495:ccrud RS01725
gene id: 1652495:ccrud_RS01725
uniprot id: A0A172QQT8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1652495:ccrud RS02350
gene id: 1652495:ccrud_RS02350
uniprot id: A0A172QR58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1652495:ccrud RS03300
gene id: 1652495:ccrud_RS03300
uniprot id: A0A172QRM5
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1652495:ccrud RS04200
gene id: 1652495:ccrud_RS04200
uniprot id: A0A172QS37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1652495:ccrud RS08440
gene id: 1652495:ccrud_RS08440
uniprot id: A0A172QU82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS12045
gene id: 1652495:ccrud_RS12045
uniprot id: A0A172QVW6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1652495:ccrud RS00545
gene id: 1652495:ccrud_RS00545
uniprot id: A0A172QQB5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1652495:ccrud RS06075
gene id: 1652495:ccrud_RS06075
uniprot id: A0A172QT32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1652495:ccrud RS02075
gene id: 1652495:ccrud_RS02075
uniprot id: A0A172QR03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1652495:ccrud RS07265
gene id: 1652495:ccrud_RS07265
uniprot id: A0A172QTK6
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1652495:ccrud RS08610
gene id: 1652495:ccrud_RS08610
uniprot id: A0A172QU78
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08560
gene id: 1652495:ccrud_RS08560
uniprot id: A0A172QU69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS06625
gene id: 1652495:ccrud_RS06625
uniprot id: A0A172QT86
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1652495:ccrud RS05255
gene id: 1652495:ccrud_RS05255
uniprot id: A0A172QXC2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1652495:ccrud RS08890
gene id: 1652495:ccrud_RS08890
uniprot id: A0A172QUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1652495:ccrud RS06940
gene id: 1652495:ccrud_RS06940
uniprot id: A0A172QTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1652495:ccrud RS11065
gene id: 1652495:ccrud_RS11065
uniprot id: A0A172QVN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1652495:ccrud RS08590
gene id: 1652495:ccrud_RS08590
uniprot id: A0A172QU84
names: Similarity
messages: Belongs to the ribF family.

1652495:ccrud RS07750
gene id: 1652495:ccrud_RS07750
uniprot id: A0A172QTY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS11385
gene id: 1652495:ccrud_RS11385
uniprot id: A0A172QVK9
names: Similarity
messages: Belongs to the fructosamine kinase family.

1652495:ccrud RS11670
gene id: 1652495:ccrud_RS11670
uniprot id: A0A172QVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1652495:ccrud RS05580
gene id: 1652495:ccrud_RS05580
uniprot id: A0A172QSU3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1652495:ccrud RS09455
gene id: 1652495:ccrud_RS09455
uniprot id: A0A172QUN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS04395
gene id: 1652495:ccrud_RS04395
uniprot id: A0A172QSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1652495:ccrud RS09815
gene id: 1652495:ccrud_RS09815
uniprot id: A0A172QUT4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1652495:ccrud RS07900
gene id: 1652495:ccrud_RS07900
uniprot id: A0A172QU19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1652495:ccrud RS09015
gene id: 1652495:ccrud_RS09015
uniprot id: A0A172QUL1
names: Similarity
messages: Belongs to the acylphosphatase family.

1652495:ccrud RS11260
gene id: 1652495:ccrud_RS11260
uniprot id: A0A172QVI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1652495:ccrud RS04850
gene id: 1652495:ccrud_RS04850
uniprot id: A0A172QSG7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1652495:ccrud RS03255
gene id: 1652495:ccrud_RS03255
uniprot id: A0A172QRL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS05800
gene id: 1652495:ccrud_RS05800
uniprot id: A0A172QSZ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1652495:ccrud RS08020
gene id: 1652495:ccrud_RS08020
uniprot id: A0A172QXA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1652495:ccrud RS12700
gene id: 1652495:ccrud_RS12700
uniprot id: A0A172QWG8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1652495:ccrud RS03335
gene id: 1652495:ccrud_RS03335
uniprot id: A0A172QRN8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1652495:ccrud RS07795
gene id: 1652495:ccrud_RS07795
uniprot id: A0A172QTT0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1652495:ccrud RS07805
gene id: 1652495:ccrud_RS07805
uniprot id: A0A172QTZ7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1652495:ccrud RS04670
gene id: 1652495:ccrud_RS04670
uniprot id: A0A172QSA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS02210
gene id: 1652495:ccrud_RS02210
uniprot id: A0A172QR35
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS08075
gene id: 1652495:ccrud_RS08075
uniprot id: A0A172QU47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1652495:ccrud RS04355
gene id: 1652495:ccrud_RS04355
uniprot id: A0A172QXA5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1652495:ccrud RS08050
gene id: 1652495:ccrud_RS08050
uniprot id: A0A172QTZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1652495:ccrud RS08345
gene id: 1652495:ccrud_RS08345
uniprot id: A0A172QU85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1652495:ccrud RS12325
gene id: 1652495:ccrud_RS12325
uniprot id: A0A172QW13
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08755
gene id: 1652495:ccrud_RS08755
uniprot id: A0A172QXB4
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS01175
gene id: 1652495:ccrud_RS01175
uniprot id: A0A172QQJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1652495:ccrud RS10870
gene id: 1652495:ccrud_RS10870
uniprot id: A0A172QVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS12095
gene id: 1652495:ccrud_RS12095
uniprot id: A0A172QVW9
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS09665
gene id: 1652495:ccrud_RS09665
uniprot id: A0A172QUW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1652495:ccrud RS08140
gene id: 1652495:ccrud_RS08140
uniprot id: A0A172QU03
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS06740
gene id: 1652495:ccrud_RS06740
uniprot id: A0A172QTG3
names: Similarity
messages: Belongs to the UPF0434 family.

1652495:ccrud RS08595
gene id: 1652495:ccrud_RS08595
uniprot id: A0A172QU88
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1652495:ccrud RS12775
gene id: 1652495:ccrud_RS12775
uniprot id: A0A172QW94
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1652495:ccrud RS02605
gene id: 1652495:ccrud_RS02605
uniprot id: A0A172QR91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1652495:ccrud RS12165
gene id: 1652495:ccrud_RS12165
uniprot id: A0A172QVZ4
names: Similarity
messages: Belongs to the peptidase S13 family.

1652495:ccrud RS08375
gene id: 1652495:ccrud_RS08375
uniprot id: A0A172QU70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1652495:ccrud RS13930
gene id: 1652495:ccrud_RS13930
uniprot id: A0A172QX15
names: Similarity
messages: Belongs to the ParB family.

1652495:ccrud RS12600
gene id: 1652495:ccrud_RS12600
uniprot id: A0A172QWC4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1652495:ccrud RS13330
gene id: 1652495:ccrud_RS13330
uniprot id: A0A172QWJ2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1652495:ccrud RS05915
gene id: 1652495:ccrud_RS05915
uniprot id: A0A172QSW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1652495:ccrud RS02880
gene id: 1652495:ccrud_RS02880
uniprot id: A0A172QRF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1652495:ccrud RS03080
gene id: 1652495:ccrud_RS03080
uniprot id: A0A172QRG9
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1652495:ccrud RS11340
gene id: 1652495:ccrud_RS11340
uniprot id: A0A172QVJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1652495:ccrud RS04960
gene id: 1652495:ccrud_RS04960
uniprot id: A0A172QSG0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS03440
gene id: 1652495:ccrud_RS03440
uniprot id: A0A172QRR1
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1652495:ccrud RS13765
gene id: 1652495:ccrud_RS13765
uniprot id: A0A172QX01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1652495:ccrud RS04160
gene id: 1652495:ccrud_RS04160
uniprot id: A0A172QS19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS04410
gene id: 1652495:ccrud_RS04410
uniprot id: A0A172QS54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1652495:ccrud RS00875
gene id: 1652495:ccrud_RS00875
uniprot id: A0A172QQF1
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1652495:ccrud RS03795
gene id: 1652495:ccrud_RS03795
uniprot id: A0A172QRW8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1652495:ccrud RS11375
gene id: 1652495:ccrud_RS11375
uniprot id: A0A172QVT5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1652495:ccrud RS01205
gene id: 1652495:ccrud_RS01205
uniprot id: A0A172QQM2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1652495:ccrud RS05795
gene id: 1652495:ccrud_RS05795
uniprot id: A0A172QSY2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1652495:ccrud RS11990
gene id: 1652495:ccrud_RS11990
uniprot id: A0A172QVU4
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1652495:ccrud RS00510
gene id: 1652495:ccrud_RS00510
uniprot id: A0A172QX46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1652495:ccrud RS03220
gene id: 1652495:ccrud_RS03220
uniprot id: A0A172QRN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1652495:ccrud RS01350
gene id: 1652495:ccrud_RS01350
uniprot id: A0A172QQM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS12980
gene id: 1652495:ccrud_RS12980
uniprot id: A0A172QWE0
names: Similarity
messages: Belongs to the universal stress protein A family.

1652495:ccrud RS02375
gene id: 1652495:ccrud_RS02375
uniprot id: A0A172QR65
names: Similarity
messages: Belongs to the DapA family.

1652495:ccrud RS13495
gene id: 1652495:ccrud_RS13495
uniprot id: A0A172QWT3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS13660
gene id: 1652495:ccrud_RS13660
uniprot id: A0A172QWW2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS02930
gene id: 1652495:ccrud_RS02930
uniprot id: A0A172QRE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS08850
gene id: 1652495:ccrud_RS08850
uniprot id: A0A172QUI1
names: Similarity
messages: Belongs to the UPF0102 family.

1652495:ccrud RS00855
gene id: 1652495:ccrud_RS00855
uniprot id: A0A172QQE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1652495:ccrud RS08475
gene id: 1652495:ccrud_RS08475
uniprot id: A0A172QUA5
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS05635
gene id: 1652495:ccrud_RS05635
uniprot id: A0A172QSW7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1652495:ccrud RS10485
gene id: 1652495:ccrud_RS10485
uniprot id: A0A172QV58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1652495:ccrud RS01625
gene id: 1652495:ccrud_RS01625
uniprot id: A0A172QQV6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1652495:ccrud RS06180
gene id: 1652495:ccrud_RS06180
uniprot id: A0A172QT50
names: Similarity
messages: Belongs to the isochorismate synthase family.

1652495:ccrud RS02405
gene id: 1652495:ccrud_RS02405
uniprot id: A0A172QR52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1652495:ccrud RS08090
gene id: 1652495:ccrud_RS08090
uniprot id: A0A172QU45
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1652495:ccrud RS03780
gene id: 1652495:ccrud_RS03780
uniprot id: A0A172QRW1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1652495:ccrud RS05150
gene id: 1652495:ccrud_RS05150
uniprot id: A0A172QSM7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1652495:ccrud RS12180
gene id: 1652495:ccrud_RS12180
uniprot id: A0A172QW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1652495:ccrud RS00145
gene id: 1652495:ccrud_RS00145
uniprot id: A0A172QQ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1652495:ccrud RS04310
gene id: 1652495:ccrud_RS04310
uniprot id: A0A172QS49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1652495:ccrud RS05025
gene id: 1652495:ccrud_RS05025
uniprot id: A0A172QSG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1652495:ccrud RS09390
gene id: 1652495:ccrud_RS09390
uniprot id: A0A172QUR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1652495:ccrud RS08625
gene id: 1652495:ccrud_RS08625
uniprot id: A0A172QUD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1652495:ccrud RS03010
gene id: 1652495:ccrud_RS03010
uniprot id: A0A172QRG1
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1652495:ccrud RS06705
gene id: 1652495:ccrud_RS06705
uniprot id: A0A172QTF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1652495:ccrud RS08270
gene id: 1652495:ccrud_RS08270
uniprot id: A0A172QU53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS10470
gene id: 1652495:ccrud_RS10470
uniprot id: A0A172QV63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1652495:ccrud RS10650
gene id: 1652495:ccrud_RS10650
uniprot id: A0A172QVD8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1652495:ccrud RS02670
gene id: 1652495:ccrud_RS02670
uniprot id: A0A172QRA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1652495:ccrud RS02205
gene id: 1652495:ccrud_RS02205
uniprot id: A0A172QR34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1652495:ccrud RS12175
gene id: 1652495:ccrud_RS12175
uniprot id: A0A172QVY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS10160
gene id: 1652495:ccrud_RS10160
uniprot id: A0A172QV01
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1652495:ccrud RS03050
gene id: 1652495:ccrud_RS03050
uniprot id: A0A172QRK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1652495:ccrud RS13875
gene id: 1652495:ccrud_RS13875
uniprot id: A0A172QX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1652495:ccrud RS10570
gene id: 1652495:ccrud_RS10570
uniprot id: A0A172QV73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1652495:ccrud RS00065
gene id: 1652495:ccrud_RS00065
uniprot id: A0A172QQ37
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1652495:ccrud RS11630
gene id: 1652495:ccrud_RS11630
uniprot id: A0A172QVN8
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1652495:ccrud RS07875
gene id: 1652495:ccrud_RS07875
uniprot id: A0A172QTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1652495:ccrud RS14560
gene id: 1652495:ccrud_RS14560
uniprot id: A0A172QY31
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1652495:ccrud RS03280
gene id: 1652495:ccrud_RS03280
uniprot id: A0A172QRP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1652495:ccrud RS11155
gene id: 1652495:ccrud_RS11155
uniprot id: A0A172QXF4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1652495:ccrud RS10975
gene id: 1652495:ccrud_RS10975
uniprot id: A0A172QVL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1652495:ccrud RS04090
gene id: 1652495:ccrud_RS04090
uniprot id: A0A172QS17
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1652495:ccrud RS09870
gene id: 1652495:ccrud_RS09870
uniprot id: A0A172QUT9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1652495:ccrud RS02635
gene id: 1652495:ccrud_RS02635
uniprot id: A0A172QRB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1652495:ccrud RS03235
gene id: 1652495:ccrud_RS03235
uniprot id: A0A172QRM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS07665
gene id: 1652495:ccrud_RS07665
uniprot id: A0A172QTU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1652495:ccrud RS02305
gene id: 1652495:ccrud_RS02305
uniprot id: A0A172QR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS05740
gene id: 1652495:ccrud_RS05740
uniprot id: A0A172QST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS10290
gene id: 1652495:ccrud_RS10290
uniprot id: A0A172QV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS11350
gene id: 1652495:ccrud_RS11350
uniprot id: A0A172QVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1652495:ccrud RS02135
gene id: 1652495:ccrud_RS02135
uniprot id: A0A172QR11
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03180
gene id: 1652495:ccrud_RS03180
uniprot id: A0A172QRI8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

1652495:ccrud RS07470
gene id: 1652495:ccrud_RS07470
uniprot id: A0A172QTT5
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS11425
gene id: 1652495:ccrud_RS11425
uniprot id: A0A172QVL6
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1652495:ccrud RS05320
gene id: 1652495:ccrud_RS05320
uniprot id: A0A172QSM6
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1652495:ccrud RS07755
gene id: 1652495:ccrud_RS07755
uniprot id: A0A172QX88
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS01395
gene id: 1652495:ccrud_RS01395
uniprot id: A0A172QQR9
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS12470
gene id: 1652495:ccrud_RS12470
uniprot id: A0A172QW45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1652495:ccrud RS13050
gene id: 1652495:ccrud_RS13050
uniprot id: A0A172QWJ8
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07170
gene id: 1652495:ccrud_RS07170
uniprot id: A0A172QTK9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS04080
gene id: 1652495:ccrud_RS04080
uniprot id: A0A172QRZ4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1652495:ccrud RS05855
gene id: 1652495:ccrud_RS05855
uniprot id: A0A172QSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1652495:ccrud RS08845
gene id: 1652495:ccrud_RS08845
uniprot id: A0A172QUA6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1652495:ccrud RS12530
gene id: 1652495:ccrud_RS12530
uniprot id: A0A172QWD6
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS04720
gene id: 1652495:ccrud_RS04720
uniprot id: A0A172QSB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1652495:ccrud RS09135
gene id: 1652495:ccrud_RS09135
uniprot id: A0A172QXC3
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1652495:ccrud RS02975
gene id: 1652495:ccrud_RS02975
uniprot id: A0A172QRG6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1652495:ccrud RS09615
gene id: 1652495:ccrud_RS09615
uniprot id: A0A172QUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1652495:ccrud RS03695
gene id: 1652495:ccrud_RS03695
uniprot id: A0A172QRY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1652495:ccrud RS08400
gene id: 1652495:ccrud_RS08400
uniprot id: A0A172QU94
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1652495:ccrud RS01860
gene id: 1652495:ccrud_RS01860
uniprot id: A0A172QQZ6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1652495:ccrud RS02265
gene id: 1652495:ccrud_RS02265
uniprot id: A0A172QR45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS02735
gene id: 1652495:ccrud_RS02735
uniprot id: A0A172QRD0
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS00535
gene id: 1652495:ccrud_RS00535
uniprot id: A0A172QQA6
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07275
gene id: 1652495:ccrud_RS07275
uniprot id: A0A172QTL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1652495:ccrud RS06965
gene id: 1652495:ccrud_RS06965
uniprot id: A0A172QTG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1652495:ccrud RS02195
gene id: 1652495:ccrud_RS02195
uniprot id: A0A172QR21
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS02110
gene id: 1652495:ccrud_RS02110
uniprot id: A0A172QR23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1652495:ccrud RS05420
gene id: 1652495:ccrud_RS05420
uniprot id: A0A172QSR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1652495:ccrud RS01790
gene id: 1652495:ccrud_RS01790
uniprot id: A0A172QQW4
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS09740
gene id: 1652495:ccrud_RS09740
uniprot id: A0A172QUX7
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1652495:ccrud RS07010
gene id: 1652495:ccrud_RS07010
uniprot id: A0A172QTJ2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS11650
gene id: 1652495:ccrud_RS11650
uniprot id: A0A172QVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1652495:ccrud RS12825
gene id: 1652495:ccrud_RS12825
uniprot id: A0A172QWA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1652495:ccrud RS00730
gene id: 1652495:ccrud_RS00730
uniprot id: A0A172QQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS06150
gene id: 1652495:ccrud_RS06150
uniprot id: A0A172QT11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS05310
gene id: 1652495:ccrud_RS05310
uniprot id: A0A172QSN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1652495:ccrud RS04860
gene id: 1652495:ccrud_RS04860
uniprot id: A0A172QSF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1652495:ccrud RS13940
gene id: 1652495:ccrud_RS13940
uniprot id: A0A172QWV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1652495:ccrud RS11935
gene id: 1652495:ccrud_RS11935
uniprot id: A0A172QVU9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1652495:ccrud RS03150
gene id: 1652495:ccrud_RS03150
uniprot id: A0A172QRJ0
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03845
gene id: 1652495:ccrud_RS03845
uniprot id: A0A172QRZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1652495:ccrud RS05760
gene id: 1652495:ccrud_RS05760
uniprot id: A0A172QSR8
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08285
gene id: 1652495:ccrud_RS08285
uniprot id: A0A172QU10
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1652495:ccrud RS03970
gene id: 1652495:ccrud_RS03970
uniprot id: A0A172QRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1652495:ccrud RS01525
gene id: 1652495:ccrud_RS01525
uniprot id: A0A172QQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Membrane

1652495:ccrud RS13900
gene id: 1652495:ccrud_RS13900
uniprot id: A0A172QWU6
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03490
gene id: 1652495:ccrud_RS03490
uniprot id: A0A172QRS1
names: Similarity
messages: Belongs to the AccD/PCCB family.

1652495:ccrud RS09845
gene id: 1652495:ccrud_RS09845
uniprot id: A0A172QUZ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1652495:ccrud RS01655
gene id: 1652495:ccrud_RS01655
uniprot id: A0A172QQS7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1652495:ccrud RS09460
gene id: 1652495:ccrud_RS09460
uniprot id: A0A172QUM9
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03410
gene id: 1652495:ccrud_RS03410
uniprot id: A0A172QRN6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1652495:ccrud RS02495
gene id: 1652495:ccrud_RS02495
uniprot id: A0A172QR63
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1652495:ccrud RS07735
gene id: 1652495:ccrud_RS07735
uniprot id: A0A172QTY8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1652495:ccrud RS13910
gene id: 1652495:ccrud_RS13910
uniprot id: A0A172QWV2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1652495:ccrud RS01705
gene id: 1652495:ccrud_RS01705
uniprot id: A0A172QX57
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1652495:ccrud RS13025
gene id: 1652495:ccrud_RS13025
uniprot id: A0A172QWK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1652495:ccrud RS09430
gene id: 1652495:ccrud_RS09430
uniprot id: A0A172QUT0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1652495:ccrud RS00345
gene id: 1652495:ccrud_RS00345
uniprot id: A0A172QQ89
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS13945
gene id: 1652495:ccrud_RS13945
uniprot id: A0A172QWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1652495:ccrud RS08820
gene id: 1652495:ccrud_RS08820
uniprot id: A0A172QUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1652495:ccrud RS06715
gene id: 1652495:ccrud_RS06715
uniprot id: A0A172QTB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS10050
gene id: 1652495:ccrud_RS10050
uniprot id: A0A172QUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS10945
gene id: 1652495:ccrud_RS10945
uniprot id: A0A172QVE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS12320
gene id: 1652495:ccrud_RS12320
uniprot id: A0A172QW14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1652495:ccrud RS03365
gene id: 1652495:ccrud_RS03365
uniprot id: A0A172QRN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS06885
gene id: 1652495:ccrud_RS06885
uniprot id: A0A172QTJ0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1652495:ccrud RS06745
gene id: 1652495:ccrud_RS06745
uniprot id: A0A172QTA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS05630
gene id: 1652495:ccrud_RS05630
uniprot id: A0A172QSV2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1652495:ccrud RS04220
gene id: 1652495:ccrud_RS04220
uniprot id: A0A172QS50
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1652495:ccrud RS09140
gene id: 1652495:ccrud_RS09140
uniprot id: A0A172QXB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1652495:ccrud RS08275
gene id: 1652495:ccrud_RS08275
uniprot id: A0A172QU17
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1652495:ccrud RS02900
gene id: 1652495:ccrud_RS02900
uniprot id: A0A172QRG0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1652495:ccrud RS10625
gene id: 1652495:ccrud_RS10625
uniprot id: A0A172QV84
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1652495:ccrud RS12205
gene id: 1652495:ccrud_RS12205
uniprot id: A0A172QVY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1652495:ccrud RS05040
gene id: 1652495:ccrud_RS05040
uniprot id: A0A172QSK7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1652495:ccrud RS08010
gene id: 1652495:ccrud_RS08010
uniprot id: A0A172QTX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1652495:ccrud RS00845
gene id: 1652495:ccrud_RS00845
uniprot id: A0A172QQG7
names: Similarity
messages: Belongs to the TPP enzyme family.

1652495:ccrud RS08580
gene id: 1652495:ccrud_RS08580
uniprot id: A0A172QUC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1652495:ccrud RS02905
gene id: 1652495:ccrud_RS02905
uniprot id: A0A172QRE3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1652495:ccrud RS02960
gene id: 1652495:ccrud_RS02960
uniprot id: A0A172QRF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1652495:ccrud RS04500
gene id: 1652495:ccrud_RS04500
uniprot id: A0A172QS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1652495:ccrud RS10060
gene id: 1652495:ccrud_RS10060
uniprot id: A0A172QV38
names: Similarity
messages: Belongs to the Fur family.

1652495:ccrud RS05780
gene id: 1652495:ccrud_RS05780
uniprot id: A0A172QST4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1652495:ccrud RS06620
gene id: 1652495:ccrud_RS06620
uniprot id: A0A172QTB0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1652495:ccrud RS07295
gene id: 1652495:ccrud_RS07295
uniprot id: A0A172QTQ0
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS01385
gene id: 1652495:ccrud_RS01385
uniprot id: A0A172QQP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS11315
gene id: 1652495:ccrud_RS11315
uniprot id: A0A172QVJ5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1652495:ccrud RS10225
gene id: 1652495:ccrud_RS10225
uniprot id: A0A172QV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS12830
gene id: 1652495:ccrud_RS12830
uniprot id: A0A172QWA3
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS11290
gene id: 1652495:ccrud_RS11290
uniprot id: A0A172QVI6
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS03055
gene id: 1652495:ccrud_RS03055
uniprot id: A0A172QRJ2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1652495:ccrud RS06140
gene id: 1652495:ccrud_RS06140
uniprot id: A0A172QT04
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1652495:ccrud RS00270
gene id: 1652495:ccrud_RS00270
uniprot id: A0A172QQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS09425
gene id: 1652495:ccrud_RS09425
uniprot id: A0A172QUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1652495:ccrud RS14050
gene id: 1652495:ccrud_RS14050
uniprot id: A0A172QXU1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS12435
gene id: 1652495:ccrud_RS12435
uniprot id: A0A172QW34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1652495:ccrud RS11410
gene id: 1652495:ccrud_RS11410
uniprot id: A0A172QVS1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1652495:ccrud RS13175
gene id: 1652495:ccrud_RS13175
uniprot id: A0A172QWG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1652495:ccrud RS03875
gene id: 1652495:ccrud_RS03875
uniprot id: A0A172QS08
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1652495:ccrud RS01700
gene id: 1652495:ccrud_RS01700
uniprot id: A0A172QQT2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1652495:ccrud RS09480
gene id: 1652495:ccrud_RS09480
uniprot id: A0A172QUM6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS08025
gene id: 1652495:ccrud_RS08025
uniprot id: A0A172QTX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1652495:ccrud RS04380
gene id: 1652495:ccrud_RS04380
uniprot id: A0A172QS58
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08695
gene id: 1652495:ccrud_RS08695
uniprot id: A0A172QUA3
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1652495:ccrud RS03315
gene id: 1652495:ccrud_RS03315
uniprot id: A0A172QRM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1652495:ccrud RS03380
gene id: 1652495:ccrud_RS03380
uniprot id: A0A172QRR5
names: Similarity
messages: Belongs to the peptidase S11 family.

1652495:ccrud RS08655
gene id: 1652495:ccrud_RS08655
uniprot id: A0A172QU79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS04735
gene id: 1652495:ccrud_RS04735
uniprot id: A0A172QSD6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1652495:ccrud RS02555
gene id: 1652495:ccrud_RS02555
uniprot id: A0A172QR72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1652495:ccrud RS05845
gene id: 1652495:ccrud_RS05845
uniprot id: A0A172QSZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1652495:ccrud RS06695
gene id: 1652495:ccrud_RS06695
uniprot id: A0A172QT94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1652495:ccrud RS12390
gene id: 1652495:ccrud_RS12390
uniprot id: A0A172QW88
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1652495:ccrud RS12210
gene id: 1652495:ccrud_RS12210
uniprot id: A0A172QVY3
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07745
gene id: 1652495:ccrud_RS07745
uniprot id: A0A172QTX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS09700
gene id: 1652495:ccrud_RS09700
uniprot id: A0A172QUS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1652495:ccrud RS11420
gene id: 1652495:ccrud_RS11420
uniprot id: A0A172QVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1652495:ccrud RS03575
gene id: 1652495:ccrud_RS03575
uniprot id: A0A172QRT9
names: Similarity
messages: Belongs to the AHA1 family.

1652495:ccrud RS02575
gene id: 1652495:ccrud_RS02575
uniprot id: A0A172QR99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1652495:ccrud RS00415
gene id: 1652495:ccrud_RS00415
uniprot id: A0A172QWW6
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS12605
gene id: 1652495:ccrud_RS12605
uniprot id: A0A172QW71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1652495:ccrud RS00580
gene id: 1652495:ccrud_RS00580
uniprot id: A0A172QQA2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07380
gene id: 1652495:ccrud_RS07380
uniprot id: A0A172QTM7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS02770
gene id: 1652495:ccrud_RS02770
uniprot id: A0A172QRB5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1652495:ccrud RS02850
gene id: 1652495:ccrud_RS02850
uniprot id: A0A172QRD7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1652495:ccrud RS04340
gene id: 1652495:ccrud_RS04340
uniprot id: A0A172QS72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1652495:ccrud RS06115
gene id: 1652495:ccrud_RS06115
uniprot id: A0A172QT54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1652495:ccrud RS02585
gene id: 1652495:ccrud_RS02585
uniprot id: A0A172QR87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1652495:ccrud RS14575
gene id: 1652495:ccrud_RS14575
uniprot id: A0A172QXZ3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1652495:ccrud RS12150
gene id: 1652495:ccrud_RS12150
uniprot id: A0A172QVX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1652495:ccrud RS07445
gene id: 1652495:ccrud_RS07445
uniprot id: A0A172QTN7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1652495:ccrud RS08000
gene id: 1652495:ccrud_RS08000
uniprot id: A0A172QTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS00310
gene id: 1652495:ccrud_RS00310
uniprot id: A0A172QQ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1652495:ccrud RS07995
gene id: 1652495:ccrud_RS07995
uniprot id: A0A172QTZ4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1652495:ccrud RS09640
gene id: 1652495:ccrud_RS09640
uniprot id: A0A172QUU5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1652495:ccrud RS05280
gene id: 1652495:ccrud_RS05280
uniprot id: A0A172QSP2
names: Similarity
messages: Belongs to the ArsC family.

1652495:ccrud RS02610
gene id: 1652495:ccrud_RS02610
uniprot id: A0A172QR83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1652495:ccrud RS13950
gene id: 1652495:ccrud_RS13950
uniprot id: A0A172QWW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1652495:ccrud RS04985
gene id: 1652495:ccrud_RS04985
uniprot id: A0A172QSJ9
names: Similarity
messages: Belongs to the FBPase class 2 family.

1652495:ccrud RS07440
gene id: 1652495:ccrud_RS07440
uniprot id: A0A172QTN3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1652495:ccrud RS11915
gene id: 1652495:ccrud_RS11915
uniprot id: A0A172QW17
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1652495:ccrud RS05930
gene id: 1652495:ccrud_RS05930
uniprot id: A0A172QSX0
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1652495:ccrud RS04495
gene id: 1652495:ccrud_RS04495
uniprot id: A0A172QS75
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1652495:ccrud RS03815
gene id: 1652495:ccrud_RS03815
uniprot id: A0A172QRX8
names: Similarity
messages: Belongs to the peptidase S16 family.

1652495:ccrud RS05945
gene id: 1652495:ccrud_RS05945
uniprot id: A0A172QSV3
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1652495:ccrud RS02245
gene id: 1652495:ccrud_RS02245
uniprot id: A0A172QR22
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1652495:ccrud RS01285
gene id: 1652495:ccrud_RS01285
uniprot id: A0A172QQN1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1652495:ccrud RS06055
gene id: 1652495:ccrud_RS06055
uniprot id: A0A172QSX3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1652495:ccrud RS11940
gene id: 1652495:ccrud_RS11940
uniprot id: A0A172QVT4
names: Similarity
messages: Belongs to the DapA family.

1652495:ccrud RS06710
gene id: 1652495:ccrud_RS06710
uniprot id: A0A172QTB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1652495:ccrud RS11095
gene id: 1652495:ccrud_RS11095
uniprot id: A0A172QVG1
names: Similarity
messages: Belongs to the hyi family.

1652495:ccrud RS09200
gene id: 1652495:ccrud_RS09200
uniprot id: A0A172QUN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1652495:ccrud RS12510
gene id: 1652495:ccrud_RS12510
uniprot id: A0A172QWA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS09105
gene id: 1652495:ccrud_RS09105
uniprot id: A0A172QUG7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1652495:ccrud RS00700
gene id: 1652495:ccrud_RS00700
uniprot id: A0A172QX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1652495:ccrud RS03390
gene id: 1652495:ccrud_RS03390
uniprot id: A0A172QRQ1
names: Similarity
messages: Belongs to the peptidase C40 family.

1652495:ccrud RS12235
gene id: 1652495:ccrud_RS12235
uniprot id: A0A172QW05
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1652495:ccrud RS10730
gene id: 1652495:ccrud_RS10730
uniprot id: A0A172QVA6
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS09785
gene id: 1652495:ccrud_RS09785
uniprot id: A0A172QUZ4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1652495:ccrud RS08045
gene id: 1652495:ccrud_RS08045
uniprot id: A0A172QTY6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1652495:ccrud RS03210
gene id: 1652495:ccrud_RS03210
uniprot id: A0A172QRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1652495:ccrud RS05660
gene id: 1652495:ccrud_RS05660
uniprot id: A0A172QSS2
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08940
gene id: 1652495:ccrud_RS08940
uniprot id: A0A172QUC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1652495:ccrud RS07695
gene id: 1652495:ccrud_RS07695
uniprot id: A0A172QTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1652495:ccrud RS04065
gene id: 1652495:ccrud_RS04065
uniprot id: A0A172QS38
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1652495:ccrud RS09440
gene id: 1652495:ccrud_RS09440
uniprot id: A0A172QUT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1652495:ccrud RS11090
gene id: 1652495:ccrud_RS11090
uniprot id: A0A172QXM9
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

1652495:ccrud RS02625
gene id: 1652495:ccrud_RS02625
uniprot id: A0A172QRC5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1652495:ccrud RS11550
gene id: 1652495:ccrud_RS11550
uniprot id: A0A172QXN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1652495:ccrud RS13460
gene id: 1652495:ccrud_RS13460
uniprot id: A0A172QWL5
names: Similarity
messages: Belongs to the PspA/IM30 family.

1652495:ccrud RS07895
gene id: 1652495:ccrud_RS07895
uniprot id: A0A172QTV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1652495:ccrud RS12385
gene id: 1652495:ccrud_RS12385
uniprot id: A0A172QXP1
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08435
gene id: 1652495:ccrud_RS08435
uniprot id: A0A172QU39
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1652495:ccrud RS01305
gene id: 1652495:ccrud_RS01305
uniprot id: A0A172QQL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1652495:ccrud RS14550
gene id: 1652495:ccrud_RS14550
uniprot id: A0A172QXY6
names: Function
messages: Involved in the transposition of the insertion sequence.

1652495:ccrud RS08480
gene id: 1652495:ccrud_RS08480
uniprot id: A0A172QU59
names: Similarity
messages: Belongs to the PspA/IM30 family.

1652495:ccrud RS09155
gene id: 1652495:ccrud_RS09155
uniprot id: A0A172QUN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1652495:ccrud RS07040
gene id: 1652495:ccrud_RS07040
uniprot id: A0A172QTI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1652495:ccrud RS06785
gene id: 1652495:ccrud_RS06785
uniprot id: A0A172QTE2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1652495:ccrud RS04305
gene id: 1652495:ccrud_RS04305
uniprot id: A0A172QS48
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1652495:ccrud RS02630
gene id: 1652495:ccrud_RS02630
uniprot id: A0A172QRB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1652495:ccrud RS07565
gene id: 1652495:ccrud_RS07565
uniprot id: A0A172QTN6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1652495:ccrud RS09500
gene id: 1652495:ccrud_RS09500
uniprot id: A0A172QUU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1652495:ccrud RS10355
gene id: 1652495:ccrud_RS10355
uniprot id: A0A172QV31
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1652495:ccrud RS02500
gene id: 1652495:ccrud_RS02500
uniprot id: A0A172QR88
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1652495:ccrud RS13400
gene id: 1652495:ccrud_RS13400
uniprot id: A0A172QWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1652495:ccrud RS13490
gene id: 1652495:ccrud_RS13490
uniprot id: A0A172QWV3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1652495:ccrud RS02615
gene id: 1652495:ccrud_RS02615
uniprot id: A0A172QRA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1652495:ccrud RS00585
gene id: 1652495:ccrud_RS00585
uniprot id: A0A172QQB3
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS07935
gene id: 1652495:ccrud_RS07935
uniprot id: A0A172QTX4
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS08775
gene id: 1652495:ccrud_RS08775
uniprot id: A0A172QUA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1652495:ccrud RS08660
gene id: 1652495:ccrud_RS08660
uniprot id: A0A172QUC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS10455
gene id: 1652495:ccrud_RS10455
uniprot id: A0A172QVA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1652495:ccrud RS11910
gene id: 1652495:ccrud_RS11910
uniprot id: A0A172QVU3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1652495:ccrud RS09445
gene id: 1652495:ccrud_RS09445
uniprot id: A0A172QUR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

1652495:ccrud RS10070
gene id: 1652495:ccrud_RS10070
uniprot id: A0A172QV44
names: Subcellular Location Annotation
messages: Membrane

1652495:ccrud RS11255
gene id: 1652495:ccrud_RS11255
uniprot id: A0A172QVQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1652495:ccrud RS06575
gene id: 1652495:ccrud_RS06575
uniprot id: A0A172QTB3
names: Similarity
messages: Belongs to the universal stress protein A family.

1652495:ccrud RS01005
gene id: 1652495:ccrud_RS01005
uniprot id: A0A172QQH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

1652495:ccrud RS05125
gene id: 1652495:ccrud_RS05125
uniprot id: A0A172QSJ2
names: Similarity
messages: Belongs to the YjdM family.

1652495:ccrud RS10165
gene id: 1652495:ccrud_RS10165
uniprot id: A0A172QV61
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.