1641:EL241 RS02410
gene id: 1641:EL241_RS02410
uniprot id: A0A378MFK6
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS04180
gene id: 1641:EL241_RS04180
uniprot id: A0A378MGW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1641:EL241 RS05035
gene id: 1641:EL241_RS05035
uniprot id: A0A378M960
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1641:EL241 RS10550
gene id: 1641:EL241_RS10550
uniprot id: A0A378MEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS02395
gene id: 1641:EL241_RS02395
uniprot id: A0A378MI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS03415
gene id: 1641:EL241_RS03415
uniprot id: A0A378MGA1
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS05325
gene id: 1641:EL241_RS05325
uniprot id: A0A378MBQ0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1641:EL241 RS08255
gene id: 1641:EL241_RS08255
uniprot id: A0A378MCL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1641:EL241 RS04530
gene id: 1641:EL241_RS04530
uniprot id: A0A378M8T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1641:EL241 RS11370
gene id: 1641:EL241_RS11370
uniprot id: A0A378MKE0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1641:EL241 RS09025
gene id: 1641:EL241_RS09025
uniprot id: A0A378MBN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1641:EL241 RS04875
gene id: 1641:EL241_RS04875
uniprot id: A0A378M934
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1641:EL241 RS02670
gene id: 1641:EL241_RS02670
uniprot id: A0A378MFS7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1641:EL241 RS04390
gene id: 1641:EL241_RS04390
uniprot id: A0A378MH07
names: Similarity
messages: Belongs to the UPF0302 family.

1641:EL241 RS13250
gene id: 1641:EL241_RS13250
uniprot id: A0A378ME66
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1641:EL241 RS06475
gene id: 1641:EL241_RS06475
uniprot id: A0A378M9V8
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS05665
gene id: 1641:EL241_RS05665
uniprot id: A0A378MB25
names: Similarity
messages: Belongs to the UPF0374 family.

1641:EL241 RS11400
gene id: 1641:EL241_RS11400
uniprot id: A0A378MD69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS12245
gene id: 1641:EL241_RS12245
uniprot id: A0A378MG02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1641:EL241 RS04215
gene id: 1641:EL241_RS04215
uniprot id: A0A378MGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1641:EL241 RS10775
gene id: 1641:EL241_RS10775
uniprot id: A0A378MCM8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the group II decarboxylase family.

1641:EL241 RS07450
gene id: 1641:EL241_RS07450
uniprot id: A0A378MCW8
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1641:EL241 RS10725
gene id: 1641:EL241_RS10725
uniprot id: A0A378MK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1641:EL241 RS12340
gene id: 1641:EL241_RS12340
uniprot id: A0A378MG21
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1641:EL241 RS08955
gene id: 1641:EL241_RS08955
uniprot id: A0A378MDU8
names: Similarity
messages: Belongs to the CvfB family.

1641:EL241 RS12395
gene id: 1641:EL241_RS12395
uniprot id: A0A378MGG0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1641:EL241 RS12890
gene id: 1641:EL241_RS12890
uniprot id: A0A378MGQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1641:EL241 RS03615
gene id: 1641:EL241_RS03615
uniprot id: A0A378MGN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1641:EL241 RS01520
gene id: 1641:EL241_RS01520
uniprot id: A0A378MF49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1641:EL241 RS07045
gene id: 1641:EL241_RS07045
uniprot id: A0A378MAF6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1641:EL241 RS12280
gene id: 1641:EL241_RS12280
uniprot id: A0A378MF90
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS09020
gene id: 1641:EL241_RS09020
uniprot id: A0A378MBJ7
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1641:EL241 RS12255
gene id: 1641:EL241_RS12255
uniprot id: A0A378MDN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1641:EL241 RS03930
gene id: 1641:EL241_RS03930
uniprot id: A0A378MJG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1641:EL241 RS12865
gene id: 1641:EL241_RS12865
uniprot id: A0A0U5ANZ6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1641:EL241 RS08800
gene id: 1641:EL241_RS08800
uniprot id: A0A378MCY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS08490
gene id: 1641:EL241_RS08490
uniprot id: A0A378MCS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1641:EL241 RS08170
gene id: 1641:EL241_RS08170
uniprot id: A0A378MIG2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1641:EL241 RS09250
gene id: 1641:EL241_RS09250
uniprot id: A0A378MDA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS03910
gene id: 1641:EL241_RS03910
uniprot id: A0A378MGP1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1641:EL241 RS03190
gene id: 1641:EL241_RS03190
uniprot id: A0A378MHR4
names: Similarity
messages: Belongs to the universal stress protein A family.

1641:EL241 RS00095
gene id: 1641:EL241_RS00095
uniprot id: A0A378MEI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

1641:EL241 RS03890
gene id: 1641:EL241_RS03890
uniprot id: A0A378MJ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1641:EL241 RS05005
gene id: 1641:EL241_RS05005
uniprot id: A0A378M941
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1641:EL241 RS12860
gene id: 1641:EL241_RS12860
uniprot id: A0A0U5AWJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1641:EL241 RS04235
gene id: 1641:EL241_RS04235
uniprot id: A0A378MJA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1641:EL241 RS02390
gene id: 1641:EL241_RS02390
uniprot id: A0A378MIC4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1641:EL241 RS10305
gene id: 1641:EL241_RS10305
uniprot id: A0A378MCG5
names: Similarity
messages: Belongs to the RibF family.

1641:EL241 RS09795
gene id: 1641:EL241_RS09795
uniprot id: A0A378MC12
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1641:EL241 RS11575
gene id: 1641:EL241_RS11575
uniprot id: A0A378MD37
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1641:EL241 RS06730
gene id: 1641:EL241_RS06730
uniprot id: A0A378MBK4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1641:EL241 RS11360
gene id: 1641:EL241_RS11360
uniprot id: A0A378MFD3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1641:EL241 RS00985
gene id: 1641:EL241_RS00985
uniprot id: A0A378MHC0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS03755
gene id: 1641:EL241_RS03755
uniprot id: A0A378MGR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1641:EL241 RS01055
gene id: 1641:EL241_RS01055
uniprot id: A0A378MHP8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1641:EL241 RS12875
gene id: 1641:EL241_RS12875
uniprot id: A0A0U4VSE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1641:EL241 RS06430
gene id: 1641:EL241_RS06430
uniprot id: A0A378M9X3
names: Similarity
messages: Belongs to the acylphosphatase family.

1641:EL241 RS04145
gene id: 1641:EL241_RS04145
uniprot id: A0A378MGV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS00630
gene id: 1641:EL241_RS00630
uniprot id: A0A378MEY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS04130
gene id: 1641:EL241_RS04130
uniprot id: A0A378MGU3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS05010
gene id: 1641:EL241_RS05010
uniprot id: A0A378M959
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1641:EL241 RS01220
gene id: 1641:EL241_RS01220
uniprot id: A0A378MGN3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1641:EL241 RS11975
gene id: 1641:EL241_RS11975
uniprot id: A0A378MDF4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1641:EL241 RS10570
gene id: 1641:EL241_RS10570
uniprot id: A0A378MCI0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1641:EL241 RS07635
gene id: 1641:EL241_RS07635
uniprot id: A0A378MAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1641:EL241 RS13075
gene id: 1641:EL241_RS13075
uniprot id: A0A378ME54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1641:EL241 RS09935
gene id: 1641:EL241_RS09935
uniprot id: A0A378MDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1641:EL241 RS01925
gene id: 1641:EL241_RS01925
uniprot id: A0A378MFA2
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS00775
gene id: 1641:EL241_RS00775
uniprot id: A0A378MEQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1641:EL241 RS04280
gene id: 1641:EL241_RS04280
uniprot id: A0A378MJP1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1641:EL241 RS07525
gene id: 1641:EL241_RS07525
uniprot id: A0A378MDF8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS12425
gene id: 1641:EL241_RS12425
uniprot id: A0A378MDV7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1641:EL241 RS03525
gene id: 1641:EL241_RS03525
uniprot id: A0A378MJ36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1641:EL241 RS01225
gene id: 1641:EL241_RS01225
uniprot id: A0A378MMJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1641:EL241 RS13425
gene id: 1641:EL241_RS13425
uniprot id: A0A378ME73
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1641:EL241 RS12790
gene id: 1641:EL241_RS12790
uniprot id: A0A0U5ANU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1641:EL241 RS05365
gene id: 1641:EL241_RS05365
uniprot id: A0A378MBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS08745
gene id: 1641:EL241_RS08745
uniprot id: A0A378ME92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1641:EL241 RS00010
gene id: 1641:EL241_RS00010
uniprot id: A0A378MG01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1641:EL241 RS11015
gene id: 1641:EL241_RS11015
uniprot id: A0A378MF84
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1641:EL241 RS00585
gene id: 1641:EL241_RS00585
uniprot id: A0A378MEL4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1641:EL241 RS07585
gene id: 1641:EL241_RS07585
uniprot id: A0A378MD35
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS04805
gene id: 1641:EL241_RS04805
uniprot id: A0A378MAJ6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1641:EL241 RS00160
gene id: 1641:EL241_RS00160
uniprot id: A0A378MLX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AgrB family.
messages: Cell membrane
messages: May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.

1641:EL241 RS08185
gene id: 1641:EL241_RS08185
uniprot id: A0A378MB37
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1641:EL241 RS11795
gene id: 1641:EL241_RS11795
uniprot id: A0A378MEU9
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS00770
gene id: 1641:EL241_RS00770
uniprot id: A0A378MEW9
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1641:EL241 RS11630
gene id: 1641:EL241_RS11630
uniprot id: A0A378MDB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1641:EL241 RS03425
gene id: 1641:EL241_RS03425
uniprot id: A0A378MGI4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1641:EL241 RS11725
gene id: 1641:EL241_RS11725
uniprot id: A0A378MD83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1641:EL241 RS06420
gene id: 1641:EL241_RS06420
uniprot id: A0A378M9Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1641:EL241 RS12220
gene id: 1641:EL241_RS12220
uniprot id: A0A378MDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1641:EL241 RS00830
gene id: 1641:EL241_RS00830
uniprot id: A0A378MF22
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1641:EL241 RS12750
gene id: 1641:EL241_RS12750
uniprot id: A0A378MFH2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1641:EL241 RS12870
gene id: 1641:EL241_RS12870
uniprot id: A0A0U4VSN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1641:EL241 RS09285
gene id: 1641:EL241_RS09285
uniprot id: A0A378MBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1641:EL241 RS04940
gene id: 1641:EL241_RS04940
uniprot id: A0A378MGH2
names: Similarity
messages: Belongs to the KdgT transporter family.

1641:EL241 RS12840
gene id: 1641:EL241_RS12840
uniprot id: A0A0U5AWS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1641:EL241 RS02900
gene id: 1641:EL241_RS02900
uniprot id: A0A378MG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS11385
gene id: 1641:EL241_RS11385
uniprot id: A0A378MD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS00085
gene id: 1641:EL241_RS00085
uniprot id: A0A378MEA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds a copper B center.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Heme A3.
messages: Membrane

1641:EL241 RS08900
gene id: 1641:EL241_RS08900
uniprot id: A0A378MED5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1641:EL241 RS01160
gene id: 1641:EL241_RS01160
uniprot id: A0A378MF21
names: Similarity
messages: Belongs to the CtsR family.

1641:EL241 RS01640
gene id: 1641:EL241_RS01640
uniprot id: A0A378MF55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1641:EL241 RS04990
gene id: 1641:EL241_RS04990
uniprot id: A0A378MBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1641:EL241 RS05215
gene id: 1641:EL241_RS05215
uniprot id: A0A378M992
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1641:EL241 RS00155
gene id: 1641:EL241_RS00155
uniprot id: A0A378MG34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1641:EL241 RS09720
gene id: 1641:EL241_RS09720
uniprot id: A0A378MC29
names: Subcellular Location Annotation
messages: Cell membrane

1641:EL241 RS12710
gene id: 1641:EL241_RS12710
uniprot id: A0A0U5AP83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1641:EL241 RS12800
gene id: 1641:EL241_RS12800
uniprot id: A0A0U5A6P6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1641:EL241 RS11880
gene id: 1641:EL241_RS11880
uniprot id: A0A378MDA4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1641:EL241 RS01185
gene id: 1641:EL241_RS01185
uniprot id: A0A378MMI2
names: Similarity
messages: Belongs to the ycf81 family.

1641:EL241 RS12550
gene id: 1641:EL241_RS12550
uniprot id: A0A378MFE0
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS03810
gene id: 1641:EL241_RS03810
uniprot id: A0A378MGI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1641:EL241 RS07715
gene id: 1641:EL241_RS07715
uniprot id: A0A378MAM2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1641:EL241 RS12060
gene id: 1641:EL241_RS12060
uniprot id: A0A378MFV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1641:EL241 RS03940
gene id: 1641:EL241_RS03940
uniprot id: A0A378MIB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1641:EL241 RS08780
gene id: 1641:EL241_RS08780
uniprot id: A0A378MBG8
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
messages: Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS08085
gene id: 1641:EL241_RS08085
uniprot id: A0A378MDU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1641:EL241 RS01880
gene id: 1641:EL241_RS01880
uniprot id: A0A378MMU6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1641:EL241 RS12770
gene id: 1641:EL241_RS12770
uniprot id: A0A378MDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1641:EL241 RS12735
gene id: 1641:EL241_RS12735
uniprot id: A0A378ME03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1641:EL241 RS03795
gene id: 1641:EL241_RS03795
uniprot id: A0A378MGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1641:EL241 RS12290
gene id: 1641:EL241_RS12290
uniprot id: A0A378MG11
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1641:EL241 RS12075
gene id: 1641:EL241_RS12075
uniprot id: A0A378MDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1641:EL241 RS06890
gene id: 1641:EL241_RS06890
uniprot id: A0A378MBP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1641:EL241 RS10010
gene id: 1641:EL241_RS10010
uniprot id: A0A378MC95
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1641:EL241 RS04610
gene id: 1641:EL241_RS04610
uniprot id: A0A378M8V7
names: Subcellular Location Annotation
messages: Cytoplasm

1641:EL241 RS08460
gene id: 1641:EL241_RS08460
uniprot id: A0A378MBA4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1641:EL241 RS04575
gene id: 1641:EL241_RS04575
uniprot id: A0A378M8U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1641:EL241 RS05535
gene id: 1641:EL241_RS05535
uniprot id: A0A378MCD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1641:EL241 RS10540
gene id: 1641:EL241_RS10540
uniprot id: A0A378MCN9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1641:EL241 RS01295
gene id: 1641:EL241_RS01295
uniprot id: A0A378MF15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1641:EL241 RS03815
gene id: 1641:EL241_RS03815
uniprot id: A0A378MGS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1641:EL241 RS00535
gene id: 1641:EL241_RS00535
uniprot id: A0A378MEP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1641:EL241 RS01330
gene id: 1641:EL241_RS01330
uniprot id: A0A378MF11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS06470
gene id: 1641:EL241_RS06470
uniprot id: A0A378M9Z0
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS11560
gene id: 1641:EL241_RS11560
uniprot id: A0A378MFI2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1641:EL241 RS04960
gene id: 1641:EL241_RS04960
uniprot id: A0A378M951
names: Similarity
messages: Belongs to the asp23 family.

1641:EL241 RS09985
gene id: 1641:EL241_RS09985
uniprot id: A0A378MJN6
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1641:EL241 RS05065
gene id: 1641:EL241_RS05065
uniprot id: A0A378MBJ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1641:EL241 RS00950
gene id: 1641:EL241_RS00950
uniprot id: A0A378MES8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1641:EL241 RS12440
gene id: 1641:EL241_RS12440
uniprot id: A0A378ML63
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS05590
gene id: 1641:EL241_RS05590
uniprot id: A0A378M9I3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1641:EL241 RS03565
gene id: 1641:EL241_RS03565
uniprot id: A0A378MJ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS07580
gene id: 1641:EL241_RS07580
uniprot id: A0A378MHZ6
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1641:EL241 RS01260
gene id: 1641:EL241_RS01260
uniprot id: A0A378MHD9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1641:EL241 RS09270
gene id: 1641:EL241_RS09270
uniprot id: A0A378MBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

1641:EL241 RS07080
gene id: 1641:EL241_RS07080
uniprot id: A0A378MA92
names: Similarity
messages: Belongs to the UPF0297 family.

1641:EL241 RS04985
gene id: 1641:EL241_RS04985
uniprot id: A0A378MGI3
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

1641:EL241 RS12825
gene id: 1641:EL241_RS12825
uniprot id: A0A0U5A6Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1641:EL241 RS08795
gene id: 1641:EL241_RS08795
uniprot id: A0A378MDR2
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1641:EL241 RS10825
gene id: 1641:EL241_RS10825
uniprot id: A0A378MEB1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1641:EL241 RS12300
gene id: 1641:EL241_RS12300
uniprot id: A0A378MDP8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1641:EL241 RS04695
gene id: 1641:EL241_RS04695
uniprot id: A0A378M8X4
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS11750
gene id: 1641:EL241_RS11750
uniprot id: A0A378MET8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1641:EL241 RS09535
gene id: 1641:EL241_RS09535
uniprot id: A0A378MBZ4
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS11950
gene id: 1641:EL241_RS11950
uniprot id: A0A378MG59
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1641:EL241 RS03835
gene id: 1641:EL241_RS03835
uniprot id: A0A378MJE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1641:EL241 RS05000
gene id: 1641:EL241_RS05000
uniprot id: A0A378M943
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1641:EL241 RS12855
gene id: 1641:EL241_RS12855
uniprot id: A0A0U5AGI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1641:EL241 RS03660
gene id: 1641:EL241_RS03660
uniprot id: A0A378MGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS06135
gene id: 1641:EL241_RS06135
uniprot id: A0A378M9P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1641:EL241 RS10535
gene id: 1641:EL241_RS10535
uniprot id: A0A378MCI6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1641:EL241 RS06140
gene id: 1641:EL241_RS06140
uniprot id: A0A378M9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1641:EL241 RS12240
gene id: 1641:EL241_RS12240
uniprot id: A0A378ML23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1641:EL241 RS08175
gene id: 1641:EL241_RS08175
uniprot id: A0A378MDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1641:EL241 RS10595
gene id: 1641:EL241_RS10595
uniprot id: A0A378MK03
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1641:EL241 RS03590
gene id: 1641:EL241_RS03590
uniprot id: A0A378MIY0
names: Similarity
messages: Belongs to the UPF0312 family.

1641:EL241 RS12625
gene id: 1641:EL241_RS12625
uniprot id: A0A378MDY6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1641:EL241 RS06400
gene id: 1641:EL241_RS06400
uniprot id: A0A378MBD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1641:EL241 RS12820
gene id: 1641:EL241_RS12820
uniprot id: A0A0U5ALQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1641:EL241 RS00600
gene id: 1641:EL241_RS00600
uniprot id: A0A378MGE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS06105
gene id: 1641:EL241_RS06105
uniprot id: A0A378M9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1641:EL241 RS07315
gene id: 1641:EL241_RS07315
uniprot id: A0A378MDA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1641:EL241 RS12520
gene id: 1641:EL241_RS12520
uniprot id: A0A378MGJ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1641:EL241 RS10580
gene id: 1641:EL241_RS10580
uniprot id: A0A378MCQ6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1641:EL241 RS00150
gene id: 1641:EL241_RS00150
uniprot id: A0A378MGS2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1641:EL241 RS09220
gene id: 1641:EL241_RS09220
uniprot id: A0A378MBT5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1641:EL241 RS04705
gene id: 1641:EL241_RS04705
uniprot id: A0A378M931
names: Similarity
messages: Belongs to the UPF0346 family.

1641:EL241 RS09490
gene id: 1641:EL241_RS09490
uniprot id: A0A378MBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS07705
gene id: 1641:EL241_RS07705
uniprot id: A0A378MAP0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1641:EL241 RS09405
gene id: 1641:EL241_RS09405
uniprot id: A0A378MDD1
names: Similarity
messages: Belongs to the Dps family.

1641:EL241 RS09115
gene id: 1641:EL241_RS09115
uniprot id: A0A378MBQ7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1641:EL241 RS04240
gene id: 1641:EL241_RS04240
uniprot id: A0A378MIJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1641:EL241 RS03990
gene id: 1641:EL241_RS03990
uniprot id: A0A378MJA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1641:EL241 RS08855
gene id: 1641:EL241_RS08855
uniprot id: A0A378MDS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1641:EL241 RS10525
gene id: 1641:EL241_RS10525
uniprot id: A0A378MCK7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1641:EL241 RS06915
gene id: 1641:EL241_RS06915
uniprot id: A0A0U5A6S8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1641:EL241 RS04970
gene id: 1641:EL241_RS04970
uniprot id: A0A378MC49
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1641:EL241 RS06200
gene id: 1641:EL241_RS06200
uniprot id: A0A378MCM6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1641:EL241 RS06555
gene id: 1641:EL241_RS06555
uniprot id: A0A378M9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

1641:EL241 RS07340
gene id: 1641:EL241_RS07340
uniprot id: A0A378MAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1641:EL241 RS12705
gene id: 1641:EL241_RS12705
uniprot id: A0A0U5ACX4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1641:EL241 RS03860
gene id: 1641:EL241_RS03860
uniprot id: A0A378MGN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 1 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1641:EL241 RS09385
gene id: 1641:EL241_RS09385
uniprot id: A0A378ME59
names: Similarity
messages: Belongs to the HesB/IscA family.

1641:EL241 RS06860
gene id: 1641:EL241_RS06860
uniprot id: A0A378MA77
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1641:EL241 RS11595
gene id: 1641:EL241_RS11595
uniprot id: A0A378MEP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1641:EL241 RS09530
gene id: 1641:EL241_RS09530
uniprot id: A0A378MBV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1641:EL241 RS08880
gene id: 1641:EL241_RS08880
uniprot id: A0A378MBK6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1641:EL241 RS06300
gene id: 1641:EL241_RS06300
uniprot id: A0A378MCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1641:EL241 RS12450
gene id: 1641:EL241_RS12450
uniprot id: A0A378MG37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1641:EL241 RS08925
gene id: 1641:EL241_RS08925
uniprot id: A0A378MBH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1641:EL241 RS01065
gene id: 1641:EL241_RS01065
uniprot id: A0A378MGL7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1641:EL241 RS01920
gene id: 1641:EL241_RS01920
uniprot id: A0A378MHR8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1641:EL241 RS13400
gene id: 1641:EL241_RS13400
uniprot id: A0A378MGI9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1641:EL241 RS06165
gene id: 1641:EL241_RS06165
uniprot id: A0A378MH39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1641:EL241 RS12835
gene id: 1641:EL241_RS12835
uniprot id: A0A0U5BPF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1641:EL241 RS04710
gene id: 1641:EL241_RS04710
uniprot id: A0A378MBY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1641:EL241 RS00430
gene id: 1641:EL241_RS00430
uniprot id: A0A378MEL5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1641:EL241 RS08840
gene id: 1641:EL241_RS08840
uniprot id: A0A378MBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1641:EL241 RS07455
gene id: 1641:EL241_RS07455
uniprot id: A0A378MBZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1641:EL241 RS05210
gene id: 1641:EL241_RS05210
uniprot id: A0A378M998
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS12285
gene id: 1641:EL241_RS12285
uniprot id: A0A378ML33
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1641:EL241 RS04350
gene id: 1641:EL241_RS04350
uniprot id: A0A378MH33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1641:EL241 RS12755
gene id: 1641:EL241_RS12755
uniprot id: A0A0U5AGK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1641:EL241 RS07295
gene id: 1641:EL241_RS07295
uniprot id: A0A378MAF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS10340
gene id: 1641:EL241_RS10340
uniprot id: A0A378MCH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1641:EL241 RS13415
gene id: 1641:EL241_RS13415
uniprot id: A0A378MEA7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1641:EL241 RS12620
gene id: 1641:EL241_RS12620
uniprot id: A0A378MDS5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1641:EL241 RS04485
gene id: 1641:EL241_RS04485
uniprot id: A0A378M8S4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1641:EL241 RS06845
gene id: 1641:EL241_RS06845
uniprot id: A0A378MCJ3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1641:EL241 RS12160
gene id: 1641:EL241_RS12160
uniprot id: A0A378MDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1641:EL241 RS06975
gene id: 1641:EL241_RS06975
uniprot id: A0A378MBR1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1641:EL241 RS09575
gene id: 1641:EL241_RS09575
uniprot id: A0A378MED9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1641:EL241 RS09420
gene id: 1641:EL241_RS09420
uniprot id: A0A378MBT4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1641:EL241 RS08475
gene id: 1641:EL241_RS08475
uniprot id: A0A378MBB3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1641:EL241 RS12850
gene id: 1641:EL241_RS12850
uniprot id: A0A0U5AP20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1641:EL241 RS06090
gene id: 1641:EL241_RS06090
uniprot id: A0A378M9R0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS12145
gene id: 1641:EL241_RS12145
uniprot id: A0A378MGB1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1641:EL241 RS12270
gene id: 1641:EL241_RS12270
uniprot id: A0A378MGE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1641:EL241 RS12880
gene id: 1641:EL241_RS12880
uniprot id: A0A0U5A6N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1641:EL241 RS11825
gene id: 1641:EL241_RS11825
uniprot id: A0A378MD88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1641:EL241 RS12885
gene id: 1641:EL241_RS12885
uniprot id: A0A0U5A6Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1641:EL241 RS01200
gene id: 1641:EL241_RS01200
uniprot id: A0A378MEW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1641:EL241 RS10715
gene id: 1641:EL241_RS10715
uniprot id: A0A378MF14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1641:EL241 RS00755
gene id: 1641:EL241_RS00755
uniprot id: A0A378MMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1641:EL241 RS08485
gene id: 1641:EL241_RS08485
uniprot id: A0A378MDK1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1641:EL241 RS11430
gene id: 1641:EL241_RS11430
uniprot id: A0A378MD34
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS12765
gene id: 1641:EL241_RS12765
uniprot id: A0A0U4VSQ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1641:EL241 RS12760
gene id: 1641:EL241_RS12760
uniprot id: A0A0U5AWJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1641:EL241 RS06690
gene id: 1641:EL241_RS06690
uniprot id: A0A378MHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1641:EL241 RS12795
gene id: 1641:EL241_RS12795
uniprot id: A0A0U5ARC8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1641:EL241 RS07780
gene id: 1641:EL241_RS07780
uniprot id: A0A378MC84
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1641:EL241 RS00955
gene id: 1641:EL241_RS00955
uniprot id: A0A378MEW0
uniprot id: Q8VN02
names: Similarity
messages: Belongs to the UPF0145 family.

1641:EL241 RS12725
gene id: 1641:EL241_RS12725
uniprot id: A0A378MDS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1641:EL241 RS07645
gene id: 1641:EL241_RS07645
uniprot id: A0A378MAQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1641:EL241 RS11395
gene id: 1641:EL241_RS11395
uniprot id: A0A378MCZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1641:EL241 RS06110
gene id: 1641:EL241_RS06110
uniprot id: A0A378MCK6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS07385
gene id: 1641:EL241_RS07385
uniprot id: A0A378MAJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1641:EL241 RS07720
gene id: 1641:EL241_RS07720
uniprot id: A0A378MAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1641:EL241 RS11635
gene id: 1641:EL241_RS11635
uniprot id: A0A378MFZ5
names: Similarity
messages: Belongs to the ArsC family.

1641:EL241 RS02940
gene id: 1641:EL241_RS02940
uniprot id: A0A378MIQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1641:EL241 RS05150
gene id: 1641:EL241_RS05150
uniprot id: A0A378M982
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1641:EL241 RS12480
gene id: 1641:EL241_RS12480
uniprot id: A0A378MGI0
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the lipoyl moiety from lipoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes. Takes part in a pathway for scavenging of lipoic acid.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

1641:EL241 RS02805
gene id: 1641:EL241_RS02805
uniprot id: A0A378MFZ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1641:EL241 RS11760
gene id: 1641:EL241_RS11760
uniprot id: A0A378MD93
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1641:EL241 RS06810
gene id: 1641:EL241_RS06810
uniprot id: A0A378MHI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1641:EL241 RS12730
gene id: 1641:EL241_RS12730
uniprot id: A0A378MDU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1641:EL241 RS12080
gene id: 1641:EL241_RS12080
uniprot id: A0A378MDF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1641:EL241 RS11835
gene id: 1641:EL241_RS11835
uniprot id: A0A378MDG0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1641:EL241 RS04690
gene id: 1641:EL241_RS04690
uniprot id: A0A378M8X8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1641:EL241 RS12265
gene id: 1641:EL241_RS12265
uniprot id: A0A378MDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1641:EL241 RS12810
gene id: 1641:EL241_RS12810
uniprot id: A0A0U4MT82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1641:EL241 RS01300
gene id: 1641:EL241_RS01300
uniprot id: A0A0U5BPG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1641:EL241 RS09915
gene id: 1641:EL241_RS09915
uniprot id: A0A378MC78
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1641:EL241 RS12225
gene id: 1641:EL241_RS12225
uniprot id: A0A378MGD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1641:EL241 RS05685
gene id: 1641:EL241_RS05685
uniprot id: A0A378M9K7
names: Similarity
messages: Belongs to the Fur family.

1641:EL241 RS07745
gene id: 1641:EL241_RS07745
uniprot id: A0A378MI44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1641:EL241 RS11655
gene id: 1641:EL241_RS11655
uniprot id: A0A378MD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1641:EL241 RS12745
gene id: 1641:EL241_RS12745
uniprot id: A0A0U5AP36
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1641:EL241 RS04330
gene id: 1641:EL241_RS04330
uniprot id: A0A378MIL6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1641:EL241 RS06930
gene id: 1641:EL241_RS06930
uniprot id: A0A378MCM0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1641:EL241 RS04365
gene id: 1641:EL241_RS04365
uniprot id: A0A378MHA1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

1641:EL241 RS07230
gene id: 1641:EL241_RS07230
uniprot id: A0A378MD89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. PTCase family.
messages: Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine. Is involved in the degradation pathway of the polyamine agmatine.
messages: Cytoplasm
messages: Homotrimer.
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1641:EL241 RS02355
gene id: 1641:EL241_RS02355
uniprot id: A0A378MHZ3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1641:EL241 RS00820
gene id: 1641:EL241_RS00820
uniprot id: A0A378MES1
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS04315
gene id: 1641:EL241_RS04315
uniprot id: A0A378MGZ6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1641:EL241 RS08660
gene id: 1641:EL241_RS08660
uniprot id: A0A378MBE7
names: Similarity
messages: Belongs to the LOG family.

1641:EL241 RS06840
gene id: 1641:EL241_RS06840
uniprot id: A0A378MD12
names: Similarity
messages: Belongs to the UPF0178 family.

1641:EL241 RS09995
gene id: 1641:EL241_RS09995
uniprot id: A0A378MC58
names: Similarity
messages: Belongs to the FlgD family.

1641:EL241 RS05305
gene id: 1641:EL241_RS05305
uniprot id: A0A378M9B4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1641:EL241 RS00145
gene id: 1641:EL241_RS00145
uniprot id: A0A378MH65
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1641:EL241 RS00575
gene id: 1641:EL241_RS00575
uniprot id: A0A378MEN7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1641:EL241 RS13080
gene id: 1641:EL241_RS13080
uniprot id: A0A378MGS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1641:EL241 RS06070
gene id: 1641:EL241_RS06070
uniprot id: A0A378MC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS03665
gene id: 1641:EL241_RS03665
uniprot id: A0A378MJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS12805
gene id: 1641:EL241_RS12805
uniprot id: A0A0U5A701
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1641:EL241 RS05915
gene id: 1641:EL241_RS05915
uniprot id: A0A378MB49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS04185
gene id: 1641:EL241_RS04185
uniprot id: A0A378MH53
names: Similarity
messages: Belongs to the TelA family.

1641:EL241 RS13105
gene id: 1641:EL241_RS13105
uniprot id: A0A378ME34
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1641:EL241 RS05980
gene id: 1641:EL241_RS05980
uniprot id: A0A378M9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1641:EL241 RS09680
gene id: 1641:EL241_RS09680
uniprot id: A0A378MC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS12140
gene id: 1641:EL241_RS12140
uniprot id: A0A378MDI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1641:EL241 RS02330
gene id: 1641:EL241_RS02330
uniprot id: A0A378MFI6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1641:EL241 RS06120
gene id: 1641:EL241_RS06120
uniprot id: A0A378MB77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1641:EL241 RS10600
gene id: 1641:EL241_RS10600
uniprot id: A0A378MF05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1641:EL241 RS06310
gene id: 1641:EL241_RS06310
uniprot id: A0A378MBB0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1641:EL241 RS09675
gene id: 1641:EL241_RS09675
uniprot id: A0A378MBY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS06075
gene id: 1641:EL241_RS06075
uniprot id: A0A378MB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS00825
gene id: 1641:EL241_RS00825
uniprot id: A0A378MEV0
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1641:EL241 RS13070
gene id: 1641:EL241_RS13070
uniprot id: A0A378MDZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1641:EL241 RS10090
gene id: 1641:EL241_RS10090
uniprot id: A0A378MCB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1641:EL241 RS06990
gene id: 1641:EL241_RS06990
uniprot id: A0A378MAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1641:EL241 RS12315
gene id: 1641:EL241_RS12315
uniprot id: A0A378MDT7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1641:EL241 RS04670
gene id: 1641:EL241_RS04670
uniprot id: A0A378MBX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1641:EL241 RS12295
gene id: 1641:EL241_RS12295
uniprot id: A0A378MDM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Belongs to the group II decarboxylase family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS06755
gene id: 1641:EL241_RS06755
uniprot id: A0A378MA83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1641:EL241 RS03975
gene id: 1641:EL241_RS03975
uniprot id: A0A378MJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1641:EL241 RS06760
gene id: 1641:EL241_RS06760
uniprot id: A0A378MCY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1641:EL241 RS07410
gene id: 1641:EL241_RS07410
uniprot id: A0A378MHV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1641:EL241 RS12815
gene id: 1641:EL241_RS12815
uniprot id: A0A0U5AR36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1641:EL241 RS12785
gene id: 1641:EL241_RS12785
uniprot id: A0A378ME18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1641:EL241 RS08750
gene id: 1641:EL241_RS08750
uniprot id: A0A378MDQ2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1641:EL241 RS07440
gene id: 1641:EL241_RS07440
uniprot id: A0A378MAM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1641:EL241 RS04230
gene id: 1641:EL241_RS04230
uniprot id: A0A378MJN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1641:EL241 RS13360
gene id: 1641:EL241_RS13360
uniprot id: A0A378MGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1641:EL241 RS09820
gene id: 1641:EL241_RS09820
uniprot id: A0A378MEY1
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

1641:EL241 RS07670
gene id: 1641:EL241_RS07670
uniprot id: A0A378MAM9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1641:EL241 RS07070
gene id: 1641:EL241_RS07070
uniprot id: A0A378MAC0
names: Similarity
messages: Belongs to the UPF0473 family.

1641:EL241 RS12135
gene id: 1641:EL241_RS12135
uniprot id: A0A378MDH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1641:EL241 RS12320
gene id: 1641:EL241_RS12320
uniprot id: A0A378MGE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1641:EL241 RS05320
gene id: 1641:EL241_RS05320
uniprot id: A0A378MCA7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1641:EL241 RS12005
gene id: 1641:EL241_RS12005
uniprot id: A0A378MFT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1641:EL241 RS07700
gene id: 1641:EL241_RS07700
uniprot id: A0A378MD66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1641:EL241 RS08275
gene id: 1641:EL241_RS08275
uniprot id: A0A378MB64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1641:EL241 RS04545
gene id: 1641:EL241_RS04545
uniprot id: A0A378MBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1641:EL241 RS12845
gene id: 1641:EL241_RS12845
uniprot id: A0A0U5A6N9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1641:EL241 RS13220
gene id: 1641:EL241_RS13220
uniprot id: A0A378MGV9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1641:EL241 RS06955
gene id: 1641:EL241_RS06955
uniprot id: A0A378MA67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1641:EL241 RS06515
gene id: 1641:EL241_RS06515
uniprot id: A0A1V0D8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1641:EL241 RS07470
gene id: 1641:EL241_RS07470
uniprot id: A0A378MAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1641:EL241 RS04785
gene id: 1641:EL241_RS04785
uniprot id: A0A378M913
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1641:EL241 RS02730
gene id: 1641:EL241_RS02730
uniprot id: A0A378MHG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1641:EL241 RS09925
gene id: 1641:EL241_RS09925
uniprot id: A0A378MF07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.

1641:EL241 RS07460
gene id: 1641:EL241_RS07460
uniprot id: A0A378MHW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1641:EL241 RS05025
gene id: 1641:EL241_RS05025
uniprot id: A0A378MGJ1
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1641:EL241 RS11375
gene id: 1641:EL241_RS11375
uniprot id: A0A378MFD9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1641:EL241 RS01305
gene id: 1641:EL241_RS01305
uniprot id: A0A378MHT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1641:EL241 RS11390
gene id: 1641:EL241_RS11390
uniprot id: A0A378MCY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1641:EL241 RS06360
gene id: 1641:EL241_RS06360
uniprot id: A0A378MBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1641:EL241 RS04255
gene id: 1641:EL241_RS04255
uniprot id: A0A378MGX4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1641:EL241 RS03290
gene id: 1641:EL241_RS03290
uniprot id: A0A378MHT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1641:EL241 RS08495
gene id: 1641:EL241_RS08495
uniprot id: A0A378MIN4
names: Similarity
messages: Belongs to the thioredoxin family.

1641:EL241 RS05420
gene id: 1641:EL241_RS05420
uniprot id: A0A378MGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1641:EL241 RS09550
gene id: 1641:EL241_RS09550
uniprot id: A0A378MC03
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1641:EL241 RS12345
gene id: 1641:EL241_RS12345
uniprot id: A0A378MDN3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1641:EL241 RS06855
gene id: 1641:EL241_RS06855
uniprot id: A0A378MA68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1641:EL241 RS10050
gene id: 1641:EL241_RS10050
uniprot id: A0A378MC72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1641:EL241 RS08155
gene id: 1641:EL241_RS08155
uniprot id: A0A378MDX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1641:EL241 RS09895
gene id: 1641:EL241_RS09895
uniprot id: A0A378MJL2
names: Subcellular Location Annotation
messages: Cytoplasm

1641:EL241 RS06880
gene id: 1641:EL241_RS06880
uniprot id: A0A378MD21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1641:EL241 RS06790
gene id: 1641:EL241_RS06790
uniprot id: A0A378MA95
names: Similarity
messages: Belongs to the Fur family.

1641:EL241 RS08065
gene id: 1641:EL241_RS08065
uniprot id: A0A378MAX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

1641:EL241 RS13455
gene id: 1641:EL241_RS13455
uniprot id: A0A378ME84
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1641:EL241 RS08825
gene id: 1641:EL241_RS08825
uniprot id: A0A378MCZ5
names: Similarity
messages: Belongs to the UPF0358 family.

1641:EL241 RS09160
gene id: 1641:EL241_RS09160
uniprot id: A0A378MBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1641:EL241 RS11870
gene id: 1641:EL241_RS11870
uniprot id: A0A378MDD5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1641:EL241 RS00655
gene id: 1641:EL241_RS00655
uniprot id: A0A378MEQ9
names: Similarity
messages: Belongs to the EsaB family.

1641:EL241 RS08510
gene id: 1641:EL241_RS08510
uniprot id: A0A378MB76
names: Subcellular Location Annotation
messages: Membrane

1641:EL241 RS05040
gene id: 1641:EL241_RS05040
uniprot id: A0A378M953
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1641:EL241 RS04540
gene id: 1641:EL241_RS04540
uniprot id: A0A378M8Z2
names: Similarity
messages: Belongs to the UPF0398 family.

1641:EL241 RS05400
gene id: 1641:EL241_RS05400
uniprot id: A0A378M9H3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.