161896:UL81 RS08645
gene id: 161896:UL81_RS08645
uniprot id: A0A0F6TBA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

161896:UL81 RS04350
gene id: 161896:UL81_RS04350
uniprot id: A0A0F6TA71
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS06310
gene id: 161896:UL81_RS06310
uniprot id: A0A0F6QYH4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS09615
gene id: 161896:UL81_RS09615
uniprot id: A0A0F6TC09
names: Similarity
messages: Belongs to the SAICAR synthetase family.

161896:UL81 RS05945
gene id: 161896:UL81_RS05945
uniprot id: A0A0F6QWU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

161896:UL81 RS04515
gene id: 161896:UL81_RS04515
uniprot id: A0A0F6QWD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

161896:UL81 RS08550
gene id: 161896:UL81_RS08550
uniprot id: A0A0F6QWY6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

161896:UL81 RS04345
gene id: 161896:UL81_RS04345
uniprot id: A0A0F6QXV3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

161896:UL81 RS10070
gene id: 161896:UL81_RS10070
uniprot id: A0A0F6QZQ8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

161896:UL81 RS08735
gene id: 161896:UL81_RS08735
uniprot id: A0A0F6TC54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

161896:UL81 RS04665
gene id: 161896:UL81_RS04665
uniprot id: A0A0F6QWE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

161896:UL81 RS09680
gene id: 161896:UL81_RS09680
uniprot id: A0A0F6TC14
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

161896:UL81 RS01095
gene id: 161896:UL81_RS01095
uniprot id: A0A0F6TA35
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

161896:UL81 RS08405
gene id: 161896:UL81_RS08405
uniprot id: A0A0F6TB92
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

161896:UL81 RS00165
gene id: 161896:UL81_RS00165
uniprot id: A0A0F6QU57
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS10025
gene id: 161896:UL81_RS10025
uniprot id: A0A0F6TCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS09645
gene id: 161896:UL81_RS09645
uniprot id: A0A0F6QY32
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS00010
gene id: 161896:UL81_RS00010
uniprot id: A0A0F6TA34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

161896:UL81 RS01635
gene id: 161896:UL81_RS01635
uniprot id: A0A0F6QUL5
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS06220
gene id: 161896:UL81_RS06220
uniprot id: A0A0F6QWX6
names: Caution
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS09835
gene id: 161896:UL81_RS09835
uniprot id: A0A0F6QZN8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS05450
gene id: 161896:UL81_RS05450
uniprot id: A0A0F6QWN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

161896:UL81 RS00150
gene id: 161896:UL81_RS00150
uniprot id: A0A0F6TA78
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

161896:UL81 RS01015
gene id: 161896:UL81_RS01015
uniprot id: A0A0F6QWN4
names: Subcellular Location Annotation
messages: Cytoplasm

161896:UL81 RS06405
gene id: 161896:UL81_RS06405
uniprot id: A0A0F6QW75
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

161896:UL81 RS06565
gene id: 161896:UL81_RS06565
uniprot id: A0A0F6TAV8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

161896:UL81 RS04505
gene id: 161896:UL81_RS04505
uniprot id: A0A0F6QXX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

161896:UL81 RS03655
gene id: 161896:UL81_RS03655
uniprot id: A0A0F6TA24
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS06335
gene id: 161896:UL81_RS06335
uniprot id: A0A0F6QYH7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

161896:UL81 RS05550
gene id: 161896:UL81_RS05550
uniprot id: A0A0F6QWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

161896:UL81 RS09070
gene id: 161896:UL81_RS09070
uniprot id: A0A0F6QXV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

161896:UL81 RS04930
gene id: 161896:UL81_RS04930
uniprot id: A0A0F6QVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

161896:UL81 RS11030
gene id: 161896:UL81_RS11030
uniprot id: A0A0F6QYI8
names: Similarity
messages: Belongs to the thioredoxin family.

161896:UL81 RS08495
gene id: 161896:UL81_RS08495
uniprot id: A0A0F6QXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161896:UL81 RS04760
gene id: 161896:UL81_RS04760
uniprot id: A0A0F6QXZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

161896:UL81 RS04800
gene id: 161896:UL81_RS04800
uniprot id: A0A0F6TAU6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

161896:UL81 RS07360
gene id: 161896:UL81_RS07360
uniprot id: A0A0F6TBH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS02085
gene id: 161896:UL81_RS02085
uniprot id: A0A0F6T9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

161896:UL81 RS11220
gene id: 161896:UL81_RS11220
uniprot id: A0A0F6TC96
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS06325
gene id: 161896:UL81_RS06325
uniprot id: A0A0F6TB73
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

161896:UL81 RS07400
gene id: 161896:UL81_RS07400
uniprot id: A0A0F6TAZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

161896:UL81 RS06190
gene id: 161896:UL81_RS06190
uniprot id: A0A0F6TAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

161896:UL81 RS05165
gene id: 161896:UL81_RS05165
uniprot id: A0A0F6TAX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

161896:UL81 RS06785
gene id: 161896:UL81_RS06785
uniprot id: A0A0F6TAX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS04960
gene id: 161896:UL81_RS04960
uniprot id: A0A0F6TAC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

161896:UL81 RS09900
gene id: 161896:UL81_RS09900
uniprot id: A0A0F6TC02
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

161896:UL81 RS00400
gene id: 161896:UL81_RS00400
uniprot id: A0A0F6TAA3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-68 and Arg-71) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

161896:UL81 RS09910
gene id: 161896:UL81_RS09910
uniprot id: A0A0F6QZP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

161896:UL81 RS05515
gene id: 161896:UL81_RS05515
uniprot id: A0A0F6QY71
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

161896:UL81 RS05540
gene id: 161896:UL81_RS05540
uniprot id: A0A0F6QY74
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS02245
gene id: 161896:UL81_RS02245
uniprot id: A0A0F6TAD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

161896:UL81 RS05785
gene id: 161896:UL81_RS05785
uniprot id: A0A0F6TB39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

161896:UL81 RS01705
gene id: 161896:UL81_RS01705
uniprot id: A0A0F6T9Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

161896:UL81 RS06780
gene id: 161896:UL81_RS06780
uniprot id: A0A0F6QX38
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

161896:UL81 RS05220
gene id: 161896:UL81_RS05220
uniprot id: A0A0F6QVU4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

161896:UL81 RS09350
gene id: 161896:UL81_RS09350
uniprot id: A0A0F6QZJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

161896:UL81 RS10265
gene id: 161896:UL81_RS10265
uniprot id: A0A0F6QXJ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

161896:UL81 RS04950
gene id: 161896:UL81_RS04950
uniprot id: A0A0F6QVR3
names: Similarity
messages: Belongs to the UPF0045 family.

161896:UL81 RS06560
gene id: 161896:UL81_RS06560
uniprot id: A0A0F6QYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

161896:UL81 RS10110
gene id: 161896:UL81_RS10110
uniprot id: A0A0F6TBH7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

161896:UL81 RS01555
gene id: 161896:UL81_RS01555
uniprot id: A0A0F6TA83
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

161896:UL81 RS00505
gene id: 161896:UL81_RS00505
uniprot id: A0A0F6T9G7
names: Similarity
messages: Belongs to the peptidase M13 family.

161896:UL81 RS09380
gene id: 161896:UL81_RS09380
uniprot id: A0A0F6TBW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS04385
gene id: 161896:UL81_RS04385
uniprot id: A0A0F6QXV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

161896:UL81 RS02535
gene id: 161896:UL81_RS02535
uniprot id: A0A0F6TAD2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

161896:UL81 RS06375
gene id: 161896:UL81_RS06375
uniprot id: A0A0F6TAR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

161896:UL81 RS00765
gene id: 161896:UL81_RS00765
uniprot id: A0A0F6T9I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

161896:UL81 RS05510
gene id: 161896:UL81_RS05510
uniprot id: A0A0F6QVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

161896:UL81 RS01285
gene id: 161896:UL81_RS01285
uniprot id: A0A0F6QWR9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

161896:UL81 RS03805
gene id: 161896:UL81_RS03805
uniprot id: A0A0F6TAN1
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01765
gene id: 161896:UL81_RS01765
uniprot id: A0A0F6QWZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

161896:UL81 RS10045
gene id: 161896:UL81_RS10045
uniprot id: A0A0F6QZQ6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

161896:UL81 RS00575
gene id: 161896:UL81_RS00575
uniprot id: A0A0F6QWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

161896:UL81 RS02850
gene id: 161896:UL81_RS02850
uniprot id: A0A0F6QVT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

161896:UL81 RS10745
gene id: 161896:UL81_RS10745
uniprot id: A0A0F6QZX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161896:UL81 RS02205
gene id: 161896:UL81_RS02205
uniprot id: A0A0F6T9U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

161896:UL81 RS11405
gene id: 161896:UL81_RS11405
uniprot id: A0A0F6TCB1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

161896:UL81 RS11795
gene id: 161896:UL81_RS11795
uniprot id: A0A0F6QWN9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

161896:UL81 RS02730
gene id: 161896:UL81_RS02730
uniprot id: A0A0F6TAS7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

161896:UL81 RS09525
gene id: 161896:UL81_RS09525
uniprot id: A0A0F6TBX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

161896:UL81 RS01020
gene id: 161896:UL81_RS01020
uniprot id: A0A0F6QV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS01320
gene id: 161896:UL81_RS01320
uniprot id: A0A0F6QVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

161896:UL81 RS07135
gene id: 161896:UL81_RS07135
uniprot id: A0A0F6TBH3
names: Similarity
messages: Belongs to the UPF0246 family.

161896:UL81 RS07715
gene id: 161896:UL81_RS07715
uniprot id: A0A0F6QWP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS00910
gene id: 161896:UL81_RS00910
uniprot id: A0A0F6QUC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

161896:UL81 RS00830
gene id: 161896:UL81_RS00830
uniprot id: A0A0F6T9J0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

161896:UL81 RS09165
gene id: 161896:UL81_RS09165
uniprot id: A0A0F6TBA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

161896:UL81 RS00160
gene id: 161896:UL81_RS00160
uniprot id: A0A2P9JYE6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

161896:UL81 RS10625
gene id: 161896:UL81_RS10625
uniprot id: A0A0F6QZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS04030
gene id: 161896:UL81_RS04030
uniprot id: A0A0F6TA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

161896:UL81 RS00540
gene id: 161896:UL81_RS00540
uniprot id: A0A0F6TA17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS09790
gene id: 161896:UL81_RS09790
uniprot id: A0A0F6QZN3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

161896:UL81 RS09345
gene id: 161896:UL81_RS09345
uniprot id: A0A0F6QX74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

161896:UL81 RS07900
gene id: 161896:UL81_RS07900
uniprot id: A0A0F6TB28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

161896:UL81 RS06320
gene id: 161896:UL81_RS06320
uniprot id: A0A0F6QWY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

161896:UL81 RS06270
gene id: 161896:UL81_RS06270
uniprot id: A0A0F6QWY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

161896:UL81 RS02400
gene id: 161896:UL81_RS02400
uniprot id: A0A0F6QVN1
names: Similarity
messages: Belongs to the PrpD family.

161896:UL81 RS11185
gene id: 161896:UL81_RS11185
uniprot id: A0A0F6QXU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS11055
gene id: 161896:UL81_RS11055
uniprot id: A0A0F6QYJ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

161896:UL81 RS01605
gene id: 161896:UL81_RS01605
uniprot id: A0A0F6TAJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

161896:UL81 RS09905
gene id: 161896:UL81_RS09905
uniprot id: A0A0F6QXF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

161896:UL81 RS07600
gene id: 161896:UL81_RS07600
uniprot id: A0A0F6TB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

161896:UL81 RS01710
gene id: 161896:UL81_RS01710
uniprot id: A0A0F6QUM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

161896:UL81 RS06790
gene id: 161896:UL81_RS06790
uniprot id: A0A0F6QWB2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

161896:UL81 RS03300
gene id: 161896:UL81_RS03300
uniprot id: A0A0F6QVY6
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

161896:UL81 RS05715
gene id: 161896:UL81_RS05715
uniprot id: A0A0F6TB32
names: Similarity
messages: Belongs to the glutamine synthetase family.

161896:UL81 RS03965
gene id: 161896:UL81_RS03965
uniprot id: A0A0F6QXP1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

161896:UL81 RS01390
gene id: 161896:UL81_RS01390
uniprot id: A0A0F6T9N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS08625
gene id: 161896:UL81_RS08625
uniprot id: A0A0F6QWZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

161896:UL81 RS07505
gene id: 161896:UL81_RS07505
uniprot id: A0A0F6QXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

161896:UL81 RS06935
gene id: 161896:UL81_RS06935
uniprot id: A0A0F6TBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS07395
gene id: 161896:UL81_RS07395
uniprot id: A0A0F6QYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS07785
gene id: 161896:UL81_RS07785
uniprot id: A0A0F6TB48
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

161896:UL81 RS10130
gene id: 161896:UL81_RS10130
uniprot id: A0A0F6QY84
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

161896:UL81 RS08420
gene id: 161896:UL81_RS08420
uniprot id: A0A0F6TBP3
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01100
gene id: 161896:UL81_RS01100
uniprot id: A0A0F6QV77
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

161896:UL81 RS07920
gene id: 161896:UL81_RS07920
uniprot id: A0A0F6QZ00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

161896:UL81 RS00420
gene id: 161896:UL81_RS00420
uniprot id: A0A0F6QWG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS03390
gene id: 161896:UL81_RS03390
uniprot id: A0A0F6QXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

161896:UL81 RS02720
gene id: 161896:UL81_RS02720
uniprot id: A0A0F6TAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

161896:UL81 RS02120
gene id: 161896:UL81_RS02120
uniprot id: A0A0F6TAC5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

161896:UL81 RS01340
gene id: 161896:UL81_RS01340
uniprot id: A0A0F6TA51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS07045
gene id: 161896:UL81_RS07045
uniprot id: A0A0F6QYS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

161896:UL81 RS07515
gene id: 161896:UL81_RS07515
uniprot id: A0A0F6QWL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

161896:UL81 RS01145
gene id: 161896:UL81_RS01145
uniprot id: A0A0F6T9L4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

161896:UL81 RS03885
gene id: 161896:UL81_RS03885
uniprot id: A0A0F6QVC3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

161896:UL81 RS04920
gene id: 161896:UL81_RS04920
uniprot id: A0A0F6QWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

161896:UL81 RS07870
gene id: 161896:UL81_RS07870
uniprot id: A0A0F6QYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

161896:UL81 RS02830
gene id: 161896:UL81_RS02830
uniprot id: A0A0F6T9X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

161896:UL81 RS06350
gene id: 161896:UL81_RS06350
uniprot id: A0A0F6TB88
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

161896:UL81 RS09330
gene id: 161896:UL81_RS09330
uniprot id: A0A0F6TBZ1
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS12085
gene id: 161896:UL81_RS12085
uniprot id: A0A0F6TBZ6
names: Similarity
messages: Belongs to the CsoR family.

161896:UL81 RS00795
gene id: 161896:UL81_RS00795
uniprot id: A0A0F6TAD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

161896:UL81 RS08195
gene id: 161896:UL81_RS08195
uniprot id: A0A0F6QXK7
names: Subcellular Location Annotation
messages: Secreted

161896:UL81 RS07385
gene id: 161896:UL81_RS07385
uniprot id: A0A0F6TBJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

161896:UL81 RS09115
gene id: 161896:UL81_RS09115
uniprot id: A0A0F6TBD1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

161896:UL81 RS05625
gene id: 161896:UL81_RS05625
uniprot id: A0A0F6QY85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

161896:UL81 RS08775
gene id: 161896:UL81_RS08775
uniprot id: A0A0F6QX10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

161896:UL81 RS00455
gene id: 161896:UL81_RS00455
uniprot id: A0A0F6QV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

161896:UL81 RS08470
gene id: 161896:UL81_RS08470
uniprot id: A0A0F6QXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

161896:UL81 RS04910
gene id: 161896:UL81_RS04910
uniprot id: A0A0F6QY07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

161896:UL81 RS09340
gene id: 161896:UL81_RS09340
uniprot id: A0A0F6TBB8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

161896:UL81 RS10075
gene id: 161896:UL81_RS10075
uniprot id: A0A0F6TC17
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS02425
gene id: 161896:UL81_RS02425
uniprot id: A0A0F6TAR0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

161896:UL81 RS03340
gene id: 161896:UL81_RS03340
uniprot id: A0A0F6QXG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

161896:UL81 RS05495
gene id: 161896:UL81_RS05495
uniprot id: A0A0F6TB04
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

161896:UL81 RS08355
gene id: 161896:UL81_RS08355
uniprot id: A0A0F6QXM3
names: Function
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.

161896:UL81 RS06170
gene id: 161896:UL81_RS06170
uniprot id: A0A0F6QWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

161896:UL81 RS05915
gene id: 161896:UL81_RS05915
uniprot id: A0A0F6TB49
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

161896:UL81 RS07875
gene id: 161896:UL81_RS07875
uniprot id: A0A0F6TBZ3
names: Similarity
messages: Belongs to the asparagine synthetase family.

161896:UL81 RS01895
gene id: 161896:UL81_RS01895
uniprot id: A0A0F6T9R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

161896:UL81 RS06515
gene id: 161896:UL81_RS06515
uniprot id: A0A0F6TBB2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

161896:UL81 RS07425
gene id: 161896:UL81_RS07425
uniprot id: A0A0F6TBH5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

161896:UL81 RS04425
gene id: 161896:UL81_RS04425
uniprot id: A0A0F6TAS3
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

161896:UL81 RS03730
gene id: 161896:UL81_RS03730
uniprot id: A0A0F6TA46
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

161896:UL81 RS06280
gene id: 161896:UL81_RS06280
uniprot id: A0A0F6QW57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS06950
gene id: 161896:UL81_RS06950
uniprot id: A0A0F6TBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

161896:UL81 RS04090
gene id: 161896:UL81_RS04090
uniprot id: A0A0F6QXQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS00985
gene id: 161896:UL81_RS00985
uniprot id: A0A0F6QUE0
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS07490
gene id: 161896:UL81_RS07490
uniprot id: A0A0F6QWL6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

161896:UL81 RS01405
gene id: 161896:UL81_RS01405
uniprot id: A0A0F6QUJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS11120
gene id: 161896:UL81_RS11120
uniprot id: A0A0F6TCB4
names: Similarity
messages: Belongs to the FPG family.

161896:UL81 RS08175
gene id: 161896:UL81_RS08175
uniprot id: A0A0F6TC16
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

161896:UL81 RS11355
gene id: 161896:UL81_RS11355
uniprot id: A0A0F6TCP4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161896:UL81 RS02010
gene id: 161896:UL81_RS02010
uniprot id: A0A0F6QUS5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

161896:UL81 RS04075
gene id: 161896:UL81_RS04075
uniprot id: A0A0F6QW70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

161896:UL81 RS06370
gene id: 161896:UL81_RS06370
uniprot id: A0A0F6QWZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS05920
gene id: 161896:UL81_RS05920
uniprot id: A0A0F6QWU1
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

161896:UL81 RS10135
gene id: 161896:UL81_RS10135
uniprot id: A0A0F6TC23
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS10630
gene id: 161896:UL81_RS10630
uniprot id: A0A0F6TBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS01470
gene id: 161896:UL81_RS01470
uniprot id: A0A0F6QUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161896:UL81 RS01755
gene id: 161896:UL81_RS01755
uniprot id: A0A0F6T9P8
names: Similarity
messages: Belongs to the asp23 family.

161896:UL81 RS04465
gene id: 161896:UL81_RS04465
uniprot id: A0A0F6TA80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

161896:UL81 RS09670
gene id: 161896:UL81_RS09670
uniprot id: A0A0F6TCA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

161896:UL81 RS05845
gene id: 161896:UL81_RS05845
uniprot id: A0A0F6QWT3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS06875
gene id: 161896:UL81_RS06875
uniprot id: A0A0F6TBR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

161896:UL81 RS01295
gene id: 161896:UL81_RS01295
uniprot id: A0A0F6QV97
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

161896:UL81 RS11240
gene id: 161896:UL81_RS11240
uniprot id: A0A0F6R038
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

161896:UL81 RS01905
gene id: 161896:UL81_RS01905
uniprot id: A0A0F6TA88
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

161896:UL81 RS05025
gene id: 161896:UL81_RS05025
uniprot id: A0A0F6QVS2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

161896:UL81 RS10015
gene id: 161896:UL81_RS10015
uniprot id: A0A0F6QXG9
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS06015
gene id: 161896:UL81_RS06015
uniprot id: A0A0F6TB46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS07575
gene id: 161896:UL81_RS07575
uniprot id: A0A0F6TBK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

161896:UL81 RS05120
gene id: 161896:UL81_RS05120
uniprot id: A0A0F6QVT4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161896:UL81 RS10020
gene id: 161896:UL81_RS10020
uniprot id: A0A0F6QZQ4
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01685
gene id: 161896:UL81_RS01685
uniprot id: A0A0F6QUM1
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

161896:UL81 RS03840
gene id: 161896:UL81_RS03840
uniprot id: A0A0F6QXM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161896:UL81 RS08245
gene id: 161896:UL81_RS08245
uniprot id: A0A0F6QXL2
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01960
gene id: 161896:UL81_RS01960
uniprot id: A0A0F6QUR9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

161896:UL81 RS05650
gene id: 161896:UL81_RS05650
uniprot id: A0A0F6QY88
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

161896:UL81 RS10600
gene id: 161896:UL81_RS10600
uniprot id: A0A0F6QZV8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161896:UL81 RS06855
gene id: 161896:UL81_RS06855
uniprot id: A0A0F6QX61
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

161896:UL81 RS06145
gene id: 161896:UL81_RS06145
uniprot id: A0A0F6QWW8
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS08450
gene id: 161896:UL81_RS08450
uniprot id: A0A0F6TB69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

161896:UL81 RS06740
gene id: 161896:UL81_RS06740
uniprot id: A0A0F6QWA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

161896:UL81 RS09890
gene id: 161896:UL81_RS09890
uniprot id: A0A0F6TBJ5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

161896:UL81 RS08975
gene id: 161896:UL81_RS08975
uniprot id: A0A0F6QX32
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

161896:UL81 RS03720
gene id: 161896:UL81_RS03720
uniprot id: A0A0F6TA29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

161896:UL81 RS11255
gene id: 161896:UL81_RS11255
uniprot id: A0A0F6TBR5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS07865
gene id: 161896:UL81_RS07865
uniprot id: A0A0F6QWQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

161896:UL81 RS02540
gene id: 161896:UL81_RS02540
uniprot id: A0A0F6QUX9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

161896:UL81 RS05825
gene id: 161896:UL81_RS05825
uniprot id: A0A0F6QW11
names: Similarity
messages: Belongs to the AHA1 family.

161896:UL81 RS05105
gene id: 161896:UL81_RS05105
uniprot id: A0A0F6TAX1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

161896:UL81 RS04730
gene id: 161896:UL81_RS04730
uniprot id: A0A0F6QXZ4
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS08680
gene id: 161896:UL81_RS08680
uniprot id: A0A0F6QZ96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

161896:UL81 RS08065
gene id: 161896:UL81_RS08065
uniprot id: A0A0F6QZ18
names: Similarity
messages: Belongs to the YjdM family.

161896:UL81 RS07700
gene id: 161896:UL81_RS07700
uniprot id: A0A0F6TBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

161896:UL81 RS04280
gene id: 161896:UL81_RS04280
uniprot id: A0A0F6QW96
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS00755
gene id: 161896:UL81_RS00755
uniprot id: A0A0F6QUB0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS08275
gene id: 161896:UL81_RS08275
uniprot id: A0A0F6TB56
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

161896:UL81 RS03615
gene id: 161896:UL81_RS03615
uniprot id: A0A0F6QXJ4
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

161896:UL81 RS03450
gene id: 161896:UL81_RS03450
uniprot id: A0A0F6QV76
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

161896:UL81 RS11245
gene id: 161896:UL81_RS11245
uniprot id: A0A0F6TCC4
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

161896:UL81 RS04055
gene id: 161896:UL81_RS04055
uniprot id: A0A0F6TAP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

161896:UL81 RS10975
gene id: 161896:UL81_RS10975
uniprot id: A0A0F6QXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

161896:UL81 RS00025
gene id: 161896:UL81_RS00025
uniprot id: A0A0F6QU43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

161896:UL81 RS09920
gene id: 161896:UL81_RS09920
uniprot id: A0A0F6QY58
names: Similarity
messages: Belongs to the peptidase S13 family.

161896:UL81 RS11870
gene id: 161896:UL81_RS11870
uniprot id: A0A0F6TBU1
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS03330
gene id: 161896:UL81_RS03330
uniprot id: A0A0F6TA16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

161896:UL81 RS07040
gene id: 161896:UL81_RS07040
uniprot id: A0A0F6QWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

161896:UL81 RS06960
gene id: 161896:UL81_RS06960
uniprot id: A0A0F6TAW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

161896:UL81 RS02165
gene id: 161896:UL81_RS02165
uniprot id: A0A0F6QX35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161896:UL81 RS06200
gene id: 161896:UL81_RS06200
uniprot id: A0A0F6TB61
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161896:UL81 RS07265
gene id: 161896:UL81_RS07265
uniprot id: A0A0F6QWI9
names: Similarity
messages: Belongs to the DprA/Smf family.

161896:UL81 RS06975
gene id: 161896:UL81_RS06975
uniprot id: A0A0F6TAY9
names: Similarity
messages: Belongs to the PspA/IM30 family.

161896:UL81 RS00730
gene id: 161896:UL81_RS00730
uniprot id: A0A0F6QUA8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

161896:UL81 RS01945
gene id: 161896:UL81_RS01945
uniprot id: A0A0F6T9R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

161896:UL81 RS01200
gene id: 161896:UL81_RS01200
uniprot id: A0A0F6QV86
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS08900
gene id: 161896:UL81_RS08900
uniprot id: A0A0F6QXT7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

161896:UL81 RS01805
gene id: 161896:UL81_RS01805
uniprot id: A0A0F6TAA2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

161896:UL81 RS05410
gene id: 161896:UL81_RS05410
uniprot id: A0A0F6QVW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

161896:UL81 RS01720
gene id: 161896:UL81_RS01720
uniprot id: A0A0F6TA75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

161896:UL81 RS05470
gene id: 161896:UL81_RS05470
uniprot id: A0A0F6TAG4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

161896:UL81 RS08105
gene id: 161896:UL81_RS08105
uniprot id: A0A0F6QZ24
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

161896:UL81 RS05655
gene id: 161896:UL81_RS05655
uniprot id: A0A0F6TB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

161896:UL81 RS07710
gene id: 161896:UL81_RS07710
uniprot id: A0A0F6TB14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

161896:UL81 RS05490
gene id: 161896:UL81_RS05490
uniprot id: A0A0F6QY68
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS04380
gene id: 161896:UL81_RS04380
uniprot id: A0A0F6QVK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

161896:UL81 RS07190
gene id: 161896:UL81_RS07190
uniprot id: A0A0F6QWI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

161896:UL81 RS00050
gene id: 161896:UL81_RS00050
uniprot id: A0A0F6QU46
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

161896:UL81 RS02940
gene id: 161896:UL81_RS02940
uniprot id: A0A0F6QXA6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

161896:UL81 RS01290
gene id: 161896:UL81_RS01290
uniprot id: A0A0F6TAH6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

161896:UL81 RS06215
gene id: 161896:UL81_RS06215
uniprot id: A0A0F6TBJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

161896:UL81 RS05130
gene id: 161896:UL81_RS05130
uniprot id: A0A0F6TAY5
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS06260
gene id: 161896:UL81_RS06260
uniprot id: A0A0F6QYG6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

161896:UL81 RS04085
gene id: 161896:UL81_RS04085
uniprot id: A0A0F6QVE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

161896:UL81 RS06240
gene id: 161896:UL81_RS06240
uniprot id: A0A0F6TAM7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

161896:UL81 RS05170
gene id: 161896:UL81_RS05170
uniprot id: A0A0F6QVT8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS03780
gene id: 161896:UL81_RS03780
uniprot id: A0A0F6TA33
names: Similarity
messages: Belongs to the UDPGP type 2 family.

161896:UL81 RS06530
gene id: 161896:UL81_RS06530
uniprot id: A0A0F6QW91
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS08820
gene id: 161896:UL81_RS08820
uniprot id: A0A0F6TBV0
names: Similarity
messages: Belongs to the peptidase M1 family.

161896:UL81 RS01900
gene id: 161896:UL81_RS01900
uniprot id: A0A0F6QVH9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

161896:UL81 RS08220
gene id: 161896:UL81_RS08220
uniprot id: A0A0F6QXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

161896:UL81 RS05355
gene id: 161896:UL81_RS05355
uniprot id: A0A0F6QVW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

161896:UL81 RS03880
gene id: 161896:UL81_RS03880
uniprot id: A0A0F6TB08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

161896:UL81 RS00690
gene id: 161896:UL81_RS00690
uniprot id: A0A0F6QV34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

161896:UL81 RS10740
gene id: 161896:UL81_RS10740
uniprot id: A0A0F6QXQ2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

161896:UL81 RS06150
gene id: 161896:UL81_RS06150
uniprot id: A0A0F6TBI6
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS00105
gene id: 161896:UL81_RS00105
uniprot id: A0A0F6T9B4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

161896:UL81 RS07810
gene id: 161896:UL81_RS07810
uniprot id: A0A0F6TBY9
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

161896:UL81 RS02810
gene id: 161896:UL81_RS02810
uniprot id: A0A0F6QV10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

161896:UL81 RS04535
gene id: 161896:UL81_RS04535
uniprot id: A0A0F6TAA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

161896:UL81 RS09540
gene id: 161896:UL81_RS09540
uniprot id: A0A0F6TCA0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

161896:UL81 RS03150
gene id: 161896:UL81_RS03150
uniprot id: A0A0F6TAH9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

161896:UL81 RS01885
gene id: 161896:UL81_RS01885
uniprot id: A0A0F6QUR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

161896:UL81 RS02180
gene id: 161896:UL81_RS02180
uniprot id: A0A0F6TAD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

161896:UL81 RS07130
gene id: 161896:UL81_RS07130
uniprot id: A0A0F6QX89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS10610
gene id: 161896:UL81_RS10610
uniprot id: A0A0F6QYE1
names: Similarity
messages: Belongs to the PRORSD1 family.

161896:UL81 RS05605
gene id: 161896:UL81_RS05605
uniprot id: A0A0F6TAH7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

161896:UL81 RS04815
gene id: 161896:UL81_RS04815
uniprot id: A0A0F6TB86
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS02280
gene id: 161896:UL81_RS02280
uniprot id: A0A0F6TAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

161896:UL81 RS08285
gene id: 161896:UL81_RS08285
uniprot id: A0A0F6TB85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

161896:UL81 RS06330
gene id: 161896:UL81_RS06330
uniprot id: A0A0F6QW64
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

161896:UL81 RS06695
gene id: 161896:UL81_RS06695
uniprot id: A0A0F6QYL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

161896:UL81 RS09390
gene id: 161896:UL81_RS09390
uniprot id: A0A0F6QZJ5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

161896:UL81 RS06265
gene id: 161896:UL81_RS06265
uniprot id: A0A0F6TB68
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

161896:UL81 RS00155
gene id: 161896:UL81_RS00155
uniprot id: A0A0F6QUX6
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

161896:UL81 RS04990
gene id: 161896:UL81_RS04990
uniprot id: A0A0F6QWI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

161896:UL81 RS06255
gene id: 161896:UL81_RS06255
uniprot id: A0A0F6QW54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

161896:UL81 RS06440
gene id: 161896:UL81_RS06440
uniprot id: A0A0F6TAS0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

161896:UL81 RS06185
gene id: 161896:UL81_RS06185
uniprot id: A0A0F6QYF7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

161896:UL81 RS08210
gene id: 161896:UL81_RS08210
uniprot id: A0A0F6QZ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

161896:UL81 RS10980
gene id: 161896:UL81_RS10980
uniprot id: A0A0F6R006
names: Similarity
messages: Belongs to the universal stress protein A family.

161896:UL81 RS03170
gene id: 161896:UL81_RS03170
uniprot id: A0A0F6QVX1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

161896:UL81 RS02905
gene id: 161896:UL81_RS02905
uniprot id: A0A0F6TAG1
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

161896:UL81 RS09505
gene id: 161896:UL81_RS09505
uniprot id: A0A0F6QXA9
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

161896:UL81 RS06305
gene id: 161896:UL81_RS06305
uniprot id: A0A0F6QW61
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

161896:UL81 RS08445
gene id: 161896:UL81_RS08445
uniprot id: A0A0F6QXN6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

161896:UL81 RS00630
gene id: 161896:UL81_RS00630
uniprot id: A0A0F6T9H6
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.

161896:UL81 RS03395
gene id: 161896:UL81_RS03395
uniprot id: A0A0F6TA20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

161896:UL81 RS09780
gene id: 161896:UL81_RS09780
uniprot id: A0A0F6TBZ2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

161896:UL81 RS06830
gene id: 161896:UL81_RS06830
uniprot id: A0A0F6QX44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

161896:UL81 RS05535
gene id: 161896:UL81_RS05535
uniprot id: A0A0F6QVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

161896:UL81 RS10960
gene id: 161896:UL81_RS10960
uniprot id: A0A0F6TC79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

161896:UL81 RS01865
gene id: 161896:UL81_RS01865
uniprot id: A0A0F6QX04
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS09915
gene id: 161896:UL81_RS09915
uniprot id: A0A0F6TCC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

161896:UL81 RS04915
gene id: 161896:UL81_RS04915
uniprot id: A0A0F6TAD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

161896:UL81 RS04985
gene id: 161896:UL81_RS04985
uniprot id: A0A0F6TAW1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

161896:UL81 RS02375
gene id: 161896:UL81_RS02375
uniprot id: A0A0F6QVM7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

161896:UL81 RS07760
gene id: 161896:UL81_RS07760
uniprot id: A0A0F6TBM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

161896:UL81 RS09145
gene id: 161896:UL81_RS09145
uniprot id: A0A0F6QXW2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

161896:UL81 RS06035
gene id: 161896:UL81_RS06035
uniprot id: A0A0F6QYD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS03650
gene id: 161896:UL81_RS03650
uniprot id: A0A0F6QW24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

161896:UL81 RS07455
gene id: 161896:UL81_RS07455
uniprot id: A0A0F6QXC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

161896:UL81 RS11075
gene id: 161896:UL81_RS11075
uniprot id: A0A0F6TBP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

161896:UL81 RS06890
gene id: 161896:UL81_RS06890
uniprot id: A0A0F6QWE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS10650
gene id: 161896:UL81_RS10650
uniprot id: A0A0F6QZW4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS10735
gene id: 161896:UL81_RS10735
uniprot id: A0A0F6TBM3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

161896:UL81 RS06520
gene id: 161896:UL81_RS06520
uniprot id: A0A0F6QX08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS11025
gene id: 161896:UL81_RS11025
uniprot id: A0A0F6TBS9
names: Similarity
messages: Belongs to the PspA/IM30 family.

161896:UL81 RS04010
gene id: 161896:UL81_RS04010
uniprot id: A0A0F6QVD9
names: Similarity
messages: Belongs to the HIBADH-related family.

161896:UL81 RS10200
gene id: 161896:UL81_RS10200
uniprot id: A0A0F6TC27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

161896:UL81 RS02470
gene id: 161896:UL81_RS02470
uniprot id: A0A0F6QX60
names: Similarity
messages: Belongs to the AccD/PCCB family.

161896:UL81 RS06290
gene id: 161896:UL81_RS06290
uniprot id: A0A0F6TB82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

161896:UL81 RS01800
gene id: 161896:UL81_RS01800
uniprot id: A0A0F6QVH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

161896:UL81 RS09040
gene id: 161896:UL81_RS09040
uniprot id: A0A0F6QXU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS04025
gene id: 161896:UL81_RS04025
uniprot id: A0A0F6QW62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS10655
gene id: 161896:UL81_RS10655
uniprot id: A0A0F6TCJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

161896:UL81 RS01790
gene id: 161896:UL81_RS01790
uniprot id: A0A0F6QWZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

161896:UL81 RS08395
gene id: 161896:UL81_RS08395
uniprot id: A0A0F6TB64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

161896:UL81 RS01780
gene id: 161896:UL81_RS01780
uniprot id: A0A0F6TA79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

161896:UL81 RS07380
gene id: 161896:UL81_RS07380
uniprot id: A0A0F6QXB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

161896:UL81 RS04560
gene id: 161896:UL81_RS04560
uniprot id: A0A0F6TB65
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

161896:UL81 RS07930
gene id: 161896:UL81_RS07930
uniprot id: A0A0F6QXH6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

161896:UL81 RS04440
gene id: 161896:UL81_RS04440
uniprot id: A0A0F6TB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

161896:UL81 RS11045
gene id: 161896:UL81_RS11045
uniprot id: A0A0F6R012
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS08515
gene id: 161896:UL81_RS08515
uniprot id: A0A0F6TB74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

161896:UL81 RS06315
gene id: 161896:UL81_RS06315
uniprot id: A0A0F6TAQ9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

161896:UL81 RS02175
gene id: 161896:UL81_RS02175
uniprot id: A0A0F6QVK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

161896:UL81 RS07320
gene id: 161896:UL81_RS07320
uniprot id: A0A0F6QYU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

161896:UL81 RS04480
gene id: 161896:UL81_RS04480
uniprot id: A0A0F6QVL1
names: Similarity
messages: Belongs to the LOG family.

161896:UL81 RS04890
gene id: 161896:UL81_RS04890
uniprot id: A0A0F6TAW5
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01130
gene id: 161896:UL81_RS01130
uniprot id: A0A0F6T9K3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

161896:UL81 RS08770
gene id: 161896:UL81_RS08770
uniprot id: A0A0F6TBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

161896:UL81 RS06110
gene id: 161896:UL81_RS06110
uniprot id: A0A0F6QYE6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

161896:UL81 RS07740
gene id: 161896:UL81_RS07740
uniprot id: A0A0F6QWP5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS01335
gene id: 161896:UL81_RS01335
uniprot id: A0A0F6QWS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

161896:UL81 RS04875
gene id: 161896:UL81_RS04875
uniprot id: A0A0F6TB90
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

161896:UL81 RS10030
gene id: 161896:UL81_RS10030
uniprot id: A0A0F6QY73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS11270
gene id: 161896:UL81_RS11270
uniprot id: A0A0F6TBU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

161896:UL81 RS03055
gene id: 161896:UL81_RS03055
uniprot id: A0A0F6QV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS00800
gene id: 161896:UL81_RS00800
uniprot id: A0A0F6QV46
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

161896:UL81 RS07250
gene id: 161896:UL81_RS07250
uniprot id: A0A0F6TBU8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

161896:UL81 RS11395
gene id: 161896:UL81_RS11395
uniprot id: A0A0F6TBV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

161896:UL81 RS01400
gene id: 161896:UL81_RS01400
uniprot id: A0A0F6TA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS02125
gene id: 161896:UL81_RS02125
uniprot id: A0A0F6QVJ8
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

161896:UL81 RS09990
gene id: 161896:UL81_RS09990
uniprot id: A0A0F6TBG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

161896:UL81 RS07755
gene id: 161896:UL81_RS07755
uniprot id: A0A0F6QXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

161896:UL81 RS03100
gene id: 161896:UL81_RS03100
uniprot id: A0A0F6TAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

161896:UL81 RS01775
gene id: 161896:UL81_RS01775
uniprot id: A0A0F6QVH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

161896:UL81 RS04775
gene id: 161896:UL81_RS04775
uniprot id: A0A0F6TAA6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

161896:UL81 RS06365
gene id: 161896:UL81_RS06365
uniprot id: A0A0F6TAN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

161896:UL81 RS06070
gene id: 161896:UL81_RS06070
uniprot id: A0A0F6QWV9
names: Similarity
messages: Belongs to the UPF0237 family.

161896:UL81 RS03480
gene id: 161896:UL81_RS03480
uniprot id: A0A0F6QXH7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

161896:UL81 RS05660
gene id: 161896:UL81_RS05660
uniprot id: A0A0F6QWR2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

161896:UL81 RS03045
gene id: 161896:UL81_RS03045
uniprot id: A0A0F6TAU3
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

161896:UL81 RS05305
gene id: 161896:UL81_RS05305
uniprot id: A0A0F6QVV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

161896:UL81 RS07935
gene id: 161896:UL81_RS07935
uniprot id: A0A0F6TBZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

161896:UL81 RS04690
gene id: 161896:UL81_RS04690
uniprot id: A0A0F6QWF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

161896:UL81 RS01935
gene id: 161896:UL81_RS01935
uniprot id: A0A0F6QUR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

161896:UL81 RS01515
gene id: 161896:UL81_RS01515
uniprot id: A0A0F6QUK3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

161896:UL81 RS07285
gene id: 161896:UL81_RS07285
uniprot id: A0A0F6TB11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

161896:UL81 RS01825
gene id: 161896:UL81_RS01825
uniprot id: A0A0F6QVH4
names: Function
names: Similarity
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.
messages: Belongs to the IucA/IucC family.

161896:UL81 RS10285
gene id: 161896:UL81_RS10285
uniprot id: A0A0F6TC60
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS07475
gene id: 161896:UL81_RS07475
uniprot id: A0A0F6TB25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

161896:UL81 RS01040
gene id: 161896:UL81_RS01040
uniprot id: A0A0F6TAF5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

161896:UL81 RS04540
gene id: 161896:UL81_RS04540
uniprot id: A0A0F6QWD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

161896:UL81 RS10375
gene id: 161896:UL81_RS10375
uniprot id: A0A0F6TBN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

161896:UL81 RS11090
gene id: 161896:UL81_RS11090
uniprot id: A0A0F6QXT6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

161896:UL81 RS01465
gene id: 161896:UL81_RS01465
uniprot id: A0A0F6TAJ0
names: Similarity
messages: Belongs to the CmpA/NrtA family.

161896:UL81 RS00945
gene id: 161896:UL81_RS00945
uniprot id: A0A0F6T9J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS06670
gene id: 161896:UL81_RS06670
uniprot id: A0A0F6QYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

161896:UL81 RS01890
gene id: 161896:UL81_RS01890
uniprot id: A0A0F6QX06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

161896:UL81 RS07120
gene id: 161896:UL81_RS07120
uniprot id: A0A0F6QYS9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

161896:UL81 RS10320
gene id: 161896:UL81_RS10320
uniprot id: A0A0F6QZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

161896:UL81 RS11130
gene id: 161896:UL81_RS11130
uniprot id: A0A0F6TBQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

161896:UL81 RS06475
gene id: 161896:UL81_RS06475
uniprot id: A0A0F6TBC2
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

161896:UL81 RS05095
gene id: 161896:UL81_RS05095
uniprot id: A0A0F6QVT1
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS06840
gene id: 161896:UL81_RS06840
uniprot id: A0A0F6QWB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

161896:UL81 RS08870
gene id: 161896:UL81_RS08870
uniprot id: A0A0F6TC62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

161896:UL81 RS08045
gene id: 161896:UL81_RS08045
uniprot id: A0A0F6TBM0
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS05345
gene id: 161896:UL81_RS05345
uniprot id: A0A0F6QWM5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

161896:UL81 RS05795
gene id: 161896:UL81_RS05795
uniprot id: A0A0F6TAJ1
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

161896:UL81 RS04295
gene id: 161896:UL81_RS04295
uniprot id: A0A0F6QXU5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

161896:UL81 RS04900
gene id: 161896:UL81_RS04900
uniprot id: A0A0F6TAB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

161896:UL81 RS09455
gene id: 161896:UL81_RS09455
uniprot id: A0A0F6QXA4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

161896:UL81 RS03185
gene id: 161896:UL81_RS03185
uniprot id: A0A0F6QXE0
names: Similarity
messages: Belongs to the DEAD box helicase family.

161896:UL81 RS06420
gene id: 161896:UL81_RS06420
uniprot id: A0A0F6QWZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS11365
gene id: 161896:UL81_RS11365
uniprot id: A0A0F6R055
names: Similarity
messages: Belongs to the thioredoxin family.

161896:UL81 RS01445
gene id: 161896:UL81_RS01445
uniprot id: A0A0F6QUJ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS06860
gene id: 161896:UL81_RS06860
uniprot id: A0A0F6TBD3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

161896:UL81 RS06970
gene id: 161896:UL81_RS06970
uniprot id: A0A0F6QYR5
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS04670
gene id: 161896:UL81_RS04670
uniprot id: A0A0F6TAT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

161896:UL81 RS08350
gene id: 161896:UL81_RS08350
uniprot id: A0A0F6TB89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

161896:UL81 RS09160
gene id: 161896:UL81_RS09160
uniprot id: A0A0F6QZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

161896:UL81 RS08745
gene id: 161896:UL81_RS08745
uniprot id: A0A0F6TBU5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

161896:UL81 RS05600
gene id: 161896:UL81_RS05600
uniprot id: A0A0F6QY82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS04370
gene id: 161896:UL81_RS04370
uniprot id: A0A0F6QWC2
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS04935
gene id: 161896:UL81_RS04935
uniprot id: A0A0F6QY09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

161896:UL81 RS00280
gene id: 161896:UL81_RS00280
uniprot id: A0A0F6TA94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

161896:UL81 RS02020
gene id: 161896:UL81_RS02020
uniprot id: A0A0F6T9S8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

161896:UL81 RS00225
gene id: 161896:UL81_RS00225
uniprot id: A0A0F6QUY5
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS07155
gene id: 161896:UL81_RS07155
uniprot id: A0A0F6QX91
names: Similarity
messages: Belongs to the MQO family.

161896:UL81 RS08805
gene id: 161896:UL81_RS08805
uniprot id: A0A0F6TC58
names: Similarity
messages: Belongs to the LacAB/RpiB family.

161896:UL81 RS02885
gene id: 161896:UL81_RS02885
uniprot id: A0A0F6QV18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

161896:UL81 RS00015
gene id: 161896:UL81_RS00015
uniprot id: A0A0F6QUW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

161896:UL81 RS05505
gene id: 161896:UL81_RS05505
uniprot id: A0A0F6TBD0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

161896:UL81 RS03765
gene id: 161896:UL81_RS03765
uniprot id: A0A0F6QXL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

161896:UL81 RS08510
gene id: 161896:UL81_RS08510
uniprot id: A0A0F6QZ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Membrane

161896:UL81 RS08385
gene id: 161896:UL81_RS08385
uniprot id: A0A0F6QWW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

161896:UL81 RS01950
gene id: 161896:UL81_RS01950
uniprot id: A0A0F6QVI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

161896:UL81 RS02920
gene id: 161896:UL81_RS02920
uniprot id: A0A0F6TAT6
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS03115
gene id: 161896:UL81_RS03115
uniprot id: A0A0F6TAJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

161896:UL81 RS01645
gene id: 161896:UL81_RS01645
uniprot id: A0A0F6T9P9
names: Similarity
messages: Belongs to the DapA family.

161896:UL81 RS00655
gene id: 161896:UL81_RS00655
uniprot id: A0A0F6TAC6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

161896:UL81 RS11335
gene id: 161896:UL81_RS11335
uniprot id: A0A0F6QXW1
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS00130
gene id: 161896:UL81_RS00130
uniprot id: A0A0F6QUX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

161896:UL81 RS07075
gene id: 161896:UL81_RS07075
uniprot id: A0A0F6TBG9
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS10270
gene id: 161896:UL81_RS10270
uniprot id: A0A0F6QZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

161896:UL81 RS01940
gene id: 161896:UL81_RS01940
uniprot id: A0A0F6QX12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

161896:UL81 RS08700
gene id: 161896:UL81_RS08700
uniprot id: A0A0F6QX00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

161896:UL81 RS04620
gene id: 161896:UL81_RS04620
uniprot id: A0A0F6TB70
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

161896:UL81 RS06555
gene id: 161896:UL81_RS06555
uniprot id: A0A0F6QW94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

161896:UL81 RS04630
gene id: 161896:UL81_RS04630
uniprot id: A0A0F6QXY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

161896:UL81 RS05250
gene id: 161896:UL81_RS05250
uniprot id: A0A0F6QY41
names: Similarity
messages: Belongs to the isochorismate synthase family.

161896:UL81 RS06295
gene id: 161896:UL81_RS06295
uniprot id: A0A0F6QWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

161896:UL81 RS10235
gene id: 161896:UL81_RS10235
uniprot id: A0A0F6TBI7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

161896:UL81 RS10475
gene id: 161896:UL81_RS10475
uniprot id: A0A0F6QZU5
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS05225
gene id: 161896:UL81_RS05225
uniprot id: A0A0F6QY39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS08110
gene id: 161896:UL81_RS08110
uniprot id: A0A0F6TC11
names: Similarity
messages: Belongs to the glutamine synthetase family.

161896:UL81 RS00980
gene id: 161896:UL81_RS00980
uniprot id: A0A0F6TAF2
names: Similarity
messages: Belongs to the GSP E family.

161896:UL81 RS09395
gene id: 161896:UL81_RS09395
uniprot id: A0A0F6TC93
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

161896:UL81 RS05930
gene id: 161896:UL81_RS05930
uniprot id: A0A0F6QW23
names: Similarity
messages: Belongs to the peptidase M18 family.

161896:UL81 RS07195
gene id: 161896:UL81_RS07195
uniprot id: A0A0F6QYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

161896:UL81 RS10800
gene id: 161896:UL81_RS10800
uniprot id: A0A0F6QZY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

161896:UL81 RS03785
gene id: 161896:UL81_RS03785
uniprot id: A0A0F6QVB0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

161896:UL81 RS07560
gene id: 161896:UL81_RS07560
uniprot id: A0A0F6TBX2
names: Similarity
messages: Belongs to the HSP15 family.

161896:UL81 RS03085
gene id: 161896:UL81_RS03085
uniprot id: A0A0F6QXC6
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

161896:UL81 RS07235
gene id: 161896:UL81_RS07235
uniprot id: A0A0F6TBG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

161896:UL81 RS05465
gene id: 161896:UL81_RS05465
uniprot id: A0A0F6QY65
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

161896:UL81 RS06850
gene id: 161896:UL81_RS06850
uniprot id: A0A0F6TAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

161896:UL81 RS07915
gene id: 161896:UL81_RS07915
uniprot id: A0A0F6QWR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

161896:UL81 RS04870
gene id: 161896:UL81_RS04870
uniprot id: A0A0F6QWH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS07950
gene id: 161896:UL81_RS07950
uniprot id: A0A0F6TBN4
names: Similarity
messages: Belongs to the glutamine synthetase family.

161896:UL81 RS01840
gene id: 161896:UL81_RS01840
uniprot id: A0A0F6QX02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

161896:UL81 RS06815
gene id: 161896:UL81_RS06815
uniprot id: A0A0F6QWB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161896:UL81 RS01560
gene id: 161896:UL81_RS01560
uniprot id: A0A0F6QUK8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

161896:UL81 RS09745
gene id: 161896:UL81_RS09745
uniprot id: A0A0F6TC19
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

161896:UL81 RS07680
gene id: 161896:UL81_RS07680
uniprot id: A0A0F6QXE6
names: Similarity
messages: Belongs to the YggT family.

161896:UL81 RS08150
gene id: 161896:UL81_RS08150
uniprot id: A0A0F6QWU3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

161896:UL81 RS00670
gene id: 161896:UL81_RS00670
uniprot id: A0A0F6TA27
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

161896:UL81 RS05950
gene id: 161896:UL81_RS05950
uniprot id: A0A0F6QW26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

161896:UL81 RS07445
gene id: 161896:UL81_RS07445
uniprot id: A0A0F6QYV5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

161896:UL81 RS09120
gene id: 161896:UL81_RS09120
uniprot id: A0A0F6QXV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

161896:UL81 RS06175
gene id: 161896:UL81_RS06175
uniprot id: A0A0F6TAM2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS09750
gene id: 161896:UL81_RS09750
uniprot id: A0A0F6QY40
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

161896:UL81 RS05910
gene id: 161896:UL81_RS05910
uniprot id: A0A0F6QYC1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

161896:UL81 RS10465
gene id: 161896:UL81_RS10465
uniprot id: A0A0F6TCH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS00845
gene id: 161896:UL81_RS00845
uniprot id: A0A0F6TA18
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS07370
gene id: 161896:UL81_RS07370
uniprot id: A0A0F6QYU9
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS09720
gene id: 161896:UL81_RS09720
uniprot id: A0A0F6TBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS00970
gene id: 161896:UL81_RS00970
uniprot id: A0A0F6TA26
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

161896:UL81 RS06470
gene id: 161896:UL81_RS06470
uniprot id: A0A0F6QX01
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

161896:UL81 RS00405
gene id: 161896:UL81_RS00405
uniprot id: A0A0F6QV04
names: Similarity
messages: Belongs to the LOG family.

161896:UL81 RS04215
gene id: 161896:UL81_RS04215
uniprot id: A0A0F6QVG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

161896:UL81 RS07510
gene id: 161896:UL81_RS07510
uniprot id: A0A0F6TBK3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

161896:UL81 RS08880
gene id: 161896:UL81_RS08880
uniprot id: A0A0F6TBV6
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

161896:UL81 RS05360
gene id: 161896:UL81_RS05360
uniprot id: A0A0F6QY51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS06250
gene id: 161896:UL81_RS06250
uniprot id: A0A0F6TAQ5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

161896:UL81 RS05480
gene id: 161896:UL81_RS05480
uniprot id: A0A0F6TAJ2
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS09845
gene id: 161896:UL81_RS09845
uniprot id: A0A0F6QY49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

161896:UL81 RS01955
gene id: 161896:UL81_RS01955
uniprot id: A0A0F6T9S4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

161896:UL81 RS02315
gene id: 161896:UL81_RS02315
uniprot id: A0A0F6QX49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS01760
gene id: 161896:UL81_RS01760
uniprot id: A0A0F6QUM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

161896:UL81 RS05810
gene id: 161896:UL81_RS05810
uniprot id: A0A0F6TAL7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

161896:UL81 RS01995
gene id: 161896:UL81_RS01995
uniprot id: A0A0F6TAB6
names: Similarity
messages: Belongs to the WXG100 family.

161896:UL81 RS05395
gene id: 161896:UL81_RS05395
uniprot id: A0A0F6TB07
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS04335
gene id: 161896:UL81_RS04335
uniprot id: A0A0F6TAS5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

161896:UL81 RS09170
gene id: 161896:UL81_RS09170
uniprot id: A0A0F6QXW5
names: Similarity
messages: Belongs to the fructosamine kinase family.

161896:UL81 RS04925
gene id: 161896:UL81_RS04925
uniprot id: A0A0F6TAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

161896:UL81 RS01500
gene id: 161896:UL81_RS01500
uniprot id: A0A0F6T9P0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

161896:UL81 RS01770
gene id: 161896:UL81_RS01770
uniprot id: A0A0F6T9Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

161896:UL81 RS00840
gene id: 161896:UL81_RS00840
uniprot id: A0A0F6QWK9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

161896:UL81 RS09565
gene id: 161896:UL81_RS09565
uniprot id: A0A0F6TBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

161896:UL81 RS08940
gene id: 161896:UL81_RS08940
uniprot id: A0A0F6QX29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS02460
gene id: 161896:UL81_RS02460
uniprot id: A0A0F6T9V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

161896:UL81 RS07100
gene id: 161896:UL81_RS07100
uniprot id: A0A0F6TAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

161896:UL81 RS07300
gene id: 161896:UL81_RS07300
uniprot id: A0A0F6TBG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

161896:UL81 RS03335
gene id: 161896:UL81_RS03335
uniprot id: A0A0F6QV67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

161896:UL81 RS06775
gene id: 161896:UL81_RS06775
uniprot id: A0A0F6TAU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS07925
gene id: 161896:UL81_RS07925
uniprot id: A0A0F6TBL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

161896:UL81 RS00855
gene id: 161896:UL81_RS00855
uniprot id: A0A0F6TAE1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161896:UL81 RS01660
gene id: 161896:UL81_RS01660
uniprot id: A0A0F6QUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS09560
gene id: 161896:UL81_RS09560
uniprot id: A0A0F6QZL0
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

161896:UL81 RS10000
gene id: 161896:UL81_RS10000
uniprot id: A0A0F6TBK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

161896:UL81 RS02405
gene id: 161896:UL81_RS02405
uniprot id: A0A0F6TAC3
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

161896:UL81 RS07665
gene id: 161896:UL81_RS07665
uniprot id: A0A0F6QWN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

161896:UL81 RS07000
gene id: 161896:UL81_RS07000
uniprot id: A0A0F6TBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

161896:UL81 RS04235
gene id: 161896:UL81_RS04235
uniprot id: A0A0F6TA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

161896:UL81 RS01910
gene id: 161896:UL81_RS01910
uniprot id: A0A0F6QUR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

161896:UL81 RS01785
gene id: 161896:UL81_RS01785
uniprot id: A0A0F6QUP5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

161896:UL81 RS10590
gene id: 161896:UL81_RS10590
uniprot id: A0A0F6TCI7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

161896:UL81 RS07270
gene id: 161896:UL81_RS07270
uniprot id: A0A0F6QYU2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

161896:UL81 RS04770
gene id: 161896:UL81_RS04770
uniprot id: A0A0F6QWG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

161896:UL81 RS02350
gene id: 161896:UL81_RS02350
uniprot id: A0A0F6QVM4
names: Similarity
messages: Belongs to the peptidase C40 family.

161896:UL81 RS07725
gene id: 161896:UL81_RS07725
uniprot id: A0A0F6TB43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

161896:UL81 RS09580
gene id: 161896:UL81_RS09580
uniprot id: A0A0F6QXB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

161896:UL81 RS00740
gene id: 161896:UL81_RS00740
uniprot id: A0A0F6QWJ6
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS03110
gene id: 161896:UL81_RS03110
uniprot id: A0A0F6QXD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

161896:UL81 RS09795
gene id: 161896:UL81_RS09795
uniprot id: A0A0F6TCB6
names: Similarity
messages: Belongs to the Nth/MutY family.

161896:UL81 RS04405
gene id: 161896:UL81_RS04405
uniprot id: A0A0F6QVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

161896:UL81 RS04675
gene id: 161896:UL81_RS04675
uniprot id: A0A0F6QVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

161896:UL81 RS08640
gene id: 161896:UL81_RS08640
uniprot id: A0A0F6QXR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

161896:UL81 RS05955
gene id: 161896:UL81_RS05955
uniprot id: A0A0F6QYC7
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

161896:UL81 RS06400
gene id: 161896:UL81_RS06400
uniprot id: A0A0F6TBK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

161896:UL81 RS04830
gene id: 161896:UL81_RS04830
uniprot id: A0A0F6QVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS07290
gene id: 161896:UL81_RS07290
uniprot id: A0A0F6QWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

161896:UL81 RS09030
gene id: 161896:UL81_RS09030
uniprot id: A0A0F6QZD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

161896:UL81 RS00380
gene id: 161896:UL81_RS00380
uniprot id: A0A0F6QV01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

161896:UL81 RS07675
gene id: 161896:UL81_RS07675
uniprot id: A0A0F6TBJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

161896:UL81 RS06945
gene id: 161896:UL81_RS06945
uniprot id: A0A0F6QYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

161896:UL81 RS03950
gene id: 161896:UL81_RS03950
uniprot id: A0A0F6QW52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS04965
gene id: 161896:UL81_RS04965
uniprot id: A0A0F6QWI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

161896:UL81 RS09865
gene id: 161896:UL81_RS09865
uniprot id: A0A0F6TC29
names: Similarity
messages: Belongs to the pantothenate synthetase family.

161896:UL81 RS10705
gene id: 161896:UL81_RS10705
uniprot id: A0A0F6TC63
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

161896:UL81 RS10170
gene id: 161896:UL81_RS10170
uniprot id: A0A0F6QZR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

161896:UL81 RS05995
gene id: 161896:UL81_RS05995
uniprot id: A0A0F6TAN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

161896:UL81 RS03210
gene id: 161896:UL81_RS03210
uniprot id: A0A0F6QXE4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

161896:UL81 RS03380
gene id: 161896:UL81_RS03380
uniprot id: A0A0F6TA04
names: Similarity
messages: Belongs to the peptidase M20A family.

161896:UL81 RS00810
gene id: 161896:UL81_RS00810
uniprot id: A0A0F6QUB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

161896:UL81 RS01365
gene id: 161896:UL81_RS01365
uniprot id: A0A0F6TA72
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS03275
gene id: 161896:UL81_RS03275
uniprot id: A0A0F6QVY3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

161896:UL81 RS05425
gene id: 161896:UL81_RS05425
uniprot id: A0A0F6QWN5
names: Similarity
messages: Belongs to the universal stress protein A family.

161896:UL81 RS06605
gene id: 161896:UL81_RS06605
uniprot id: A0A0F6QW99
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS02710
gene id: 161896:UL81_RS02710
uniprot id: A0A0F6QUZ9
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

161896:UL81 RS06410
gene id: 161896:UL81_RS06410
uniprot id: A0A0F6QYI7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

161896:UL81 RS02685
gene id: 161896:UL81_RS02685
uniprot id: A0A0F6QUZ6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

161896:UL81 RS06235
gene id: 161896:UL81_RS06235
uniprot id: A0A0F6QYG3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

161896:UL81 RS03635
gene id: 161896:UL81_RS03635
uniprot id: A0A0F6QV91
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

161896:UL81 RS07220
gene id: 161896:UL81_RS07220
uniprot id: A0A0F6QYT8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

161896:UL81 RS08215
gene id: 161896:UL81_RS08215
uniprot id: A0A0F6TB80
names: Similarity
messages: Belongs to the phosphohexose mutase family.

161896:UL81 RS00460
gene id: 161896:UL81_RS00460
uniprot id: A0A0F6TAB0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

161896:UL81 RS07090
gene id: 161896:UL81_RS07090
uniprot id: A0A0F6QWG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

161896:UL81 RS03520
gene id: 161896:UL81_RS03520
uniprot id: A0A0F6TA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

161896:UL81 RS07165
gene id: 161896:UL81_RS07165
uniprot id: A0A0F6QWH7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

161896:UL81 RS06940
gene id: 161896:UL81_RS06940
uniprot id: A0A0F6QWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS11800
gene id: 161896:UL81_RS11800
uniprot id: A0A0F6QYY0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

161896:UL81 RS10725
gene id: 161896:UL81_RS10725
uniprot id: A0A0F6TC88
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

161896:UL81 RS07150
gene id: 161896:UL81_RS07150
uniprot id: A0A0F6TAX4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

161896:UL81 RS02000
gene id: 161896:UL81_RS02000
uniprot id: A0A0F6QVI6
names: Similarity
messages: Belongs to the WXG100 family.

161896:UL81 RS09085
gene id: 161896:UL81_RS09085
uniprot id: A0A0F6QZE4
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS06380
gene id: 161896:UL81_RS06380
uniprot id: A0A0F6QW71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

161896:UL81 RS07105
gene id: 161896:UL81_RS07105
uniprot id: A0A0F6QX87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

161896:UL81 RS10495
gene id: 161896:UL81_RS10495
uniprot id: A0A0F6QXM4
names: Similarity
messages: Belongs to the AccD/PCCB family.

161896:UL81 RS09760
gene id: 161896:UL81_RS09760
uniprot id: A0A0F6QXD8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

161896:UL81 RS08410
gene id: 161896:UL81_RS08410
uniprot id: A0A0F6QWX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

161896:UL81 RS05560
gene id: 161896:UL81_RS05560
uniprot id: A0A0F6QVY2
names: Similarity
messages: Belongs to the UPF0434 family.

161896:UL81 RS01525
gene id: 161896:UL81_RS01525
uniprot id: A0A0F6TAJ4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

161896:UL81 RS01850
gene id: 161896:UL81_RS01850
uniprot id: A0A0F6QVH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

161896:UL81 RS11060
gene id: 161896:UL81_RS11060
uniprot id: A0A0F6TCB0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS06355
gene id: 161896:UL81_RS06355
uniprot id: A0A0F6QW68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

161896:UL81 RS07660
gene id: 161896:UL81_RS07660
uniprot id: A0A0F6TB37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

161896:UL81 RS05960
gene id: 161896:UL81_RS05960
uniprot id: A0A0F6TBH0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

161896:UL81 RS05085
gene id: 161896:UL81_RS05085
uniprot id: A0A0F6QWK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS04780
gene id: 161896:UL81_RS04780
uniprot id: A0A0F6QVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

161896:UL81 RS07390
gene id: 161896:UL81_RS07390
uniprot id: A0A0F6QWK4
names: Similarity
messages: Belongs to the acylphosphatase family.

161896:UL81 RS09135
gene id: 161896:UL81_RS09135
uniprot id: A0A0F6QZF0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

161896:UL81 RS04645
gene id: 161896:UL81_RS04645
uniprot id: A0A0F6TA95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

161896:UL81 RS10535
gene id: 161896:UL81_RS10535
uniprot id: A0A0F6QYD2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

161896:UL81 RS08565
gene id: 161896:UL81_RS08565
uniprot id: A0A0F6QXQ0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

161896:UL81 RS09080
gene id: 161896:UL81_RS09080
uniprot id: A0A0F6QX46
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

161896:UL81 RS07335
gene id: 161896:UL81_RS07335
uniprot id: A0A0F6TAY6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

161896:UL81 RS09755
gene id: 161896:UL81_RS09755
uniprot id: A0A0F6TBE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS01025
gene id: 161896:UL81_RS01025
uniprot id: A0A0F6TA30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

161896:UL81 RS07485
gene id: 161896:UL81_RS07485
uniprot id: A0A0F6TBI0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS11360
gene id: 161896:UL81_RS11360
uniprot id: A0A0F6QXW3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

161896:UL81 RS10970
gene id: 161896:UL81_RS10970
uniprot id: A0A0F6TCL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

161896:UL81 RS10275
gene id: 161896:UL81_RS10275
uniprot id: A0A0F6TCG0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

161896:UL81 RS06040
gene id: 161896:UL81_RS06040
uniprot id: A0A0F6TB62
names: Similarity
messages: Belongs to the peptidase C40 family.

161896:UL81 RS09355
gene id: 161896:UL81_RS09355
uniprot id: A0A0F6TBF0
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01125
gene id: 161896:UL81_RS01125
uniprot id: A0A0F6QV79
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

161896:UL81 RS04205
gene id: 161896:UL81_RS04205
uniprot id: A0A0F6QW86
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

161896:UL81 RS00990
gene id: 161896:UL81_RS00990
uniprot id: A0A0F6QWN1
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS02040
gene id: 161896:UL81_RS02040
uniprot id: A0A0F6QUS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

161896:UL81 RS05665
gene id: 161896:UL81_RS05665
uniprot id: A0A0F6TAI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

161896:UL81 RS09925
gene id: 161896:UL81_RS09925
uniprot id: A0A0F6TC35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

161896:UL81 RS06205
gene id: 161896:UL81_RS06205
uniprot id: A0A0F6QW48
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

161896:UL81 RS00815
gene id: 161896:UL81_RS00815
uniprot id: A0A0F6QWK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

161896:UL81 RS08740
gene id: 161896:UL81_RS08740
uniprot id: A0A0F6QXS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

161896:UL81 RS05800
gene id: 161896:UL81_RS05800
uniprot id: A0A0F6QW08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

161896:UL81 RS07260
gene id: 161896:UL81_RS07260
uniprot id: A0A0F6TBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

161896:UL81 RS09530
gene id: 161896:UL81_RS09530
uniprot id: A0A0F6QXB2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

161896:UL81 RS04320
gene id: 161896:UL81_RS04320
uniprot id: A0A0F6QXV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

161896:UL81 RS10185
gene id: 161896:UL81_RS10185
uniprot id: A0A0F6TBL8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS08345
gene id: 161896:UL81_RS08345
uniprot id: A0A0F6QZ52
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

161896:UL81 RS02235
gene id: 161896:UL81_RS02235
uniprot id: A0A0F6QUU7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

161896:UL81 RS07060
gene id: 161896:UL81_RS07060
uniprot id: A0A0F6TBT4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

161896:UL81 RS04315
gene id: 161896:UL81_RS04315
uniprot id: A0A0F6QVI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

161896:UL81 RS05545
gene id: 161896:UL81_RS05545
uniprot id: A0A0F6TAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

161896:UL81 RS04160
gene id: 161896:UL81_RS04160
uniprot id: A0A0F6QVF8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

161896:UL81 RS11260
gene id: 161896:UL81_RS11260
uniprot id: A0A0F6QXV1
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

161896:UL81 RS03260
gene id: 161896:UL81_RS03260
uniprot id: A0A0F6QXF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

161896:UL81 RS04240
gene id: 161896:UL81_RS04240
uniprot id: A0A0F6QVG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS00695
gene id: 161896:UL81_RS00695
uniprot id: A0A0F6T9I0
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS08475
gene id: 161896:UL81_RS08475
uniprot id: A0A0F6TBP7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

161896:UL81 RS02495
gene id: 161896:UL81_RS02495
uniprot id: A0A0F6QX63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161896:UL81 RS00205
gene id: 161896:UL81_RS00205
uniprot id: A0A0F6TA89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

161896:UL81 RS10085
gene id: 161896:UL81_RS10085
uniprot id: A0A0F6TCE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

161896:UL81 RS01620
gene id: 161896:UL81_RS01620
uniprot id: A0A0F6TA87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

161896:UL81 RS00445
gene id: 161896:UL81_RS00445
uniprot id: A0A0F6QWG4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

161896:UL81 RS05205
gene id: 161896:UL81_RS05205
uniprot id: A0A0F6TAE3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

161896:UL81 RS00890
gene id: 161896:UL81_RS00890
uniprot id: A0A0F6QUC6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

161896:UL81 RS03735
gene id: 161896:UL81_RS03735
uniprot id: A0A0F6QVA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

161896:UL81 RS04140
gene id: 161896:UL81_RS04140
uniprot id: A0A0F6QXR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

161896:UL81 RS03955
gene id: 161896:UL81_RS03955
uniprot id: A0A0F6TAQ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

161896:UL81 RS00825
gene id: 161896:UL81_RS00825
uniprot id: A0A0F6QV48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

161896:UL81 RS06610
gene id: 161896:UL81_RS06610
uniprot id: A0A0F6QYL2
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

161896:UL81 RS09140
gene id: 161896:UL81_RS09140
uniprot id: A0A0F6TC77
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

161896:UL81 RS03475
gene id: 161896:UL81_RS03475
uniprot id: A0A0F6QV78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

161896:UL81 RS00645
gene id: 161896:UL81_RS00645
uniprot id: A0A0F6QUA2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

161896:UL81 RS01925
gene id: 161896:UL81_RS01925
uniprot id: A0A0F6QVI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

161896:UL81 RS09155
gene id: 161896:UL81_RS09155
uniprot id: A0A0F6QX52
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

161896:UL81 RS08865
gene id: 161896:UL81_RS08865
uniprot id: A0A0F6QZB8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

161896:UL81 RS05595
gene id: 161896:UL81_RS05595
uniprot id: A0A0F6QVY5
names: Similarity
messages: Belongs to the TlyA family.

161896:UL81 RS07655
gene id: 161896:UL81_RS07655
uniprot id: A0A0F6QXE3
names: Similarity
messages: Belongs to the asparaginase 1 family.

161896:UL81 RS01700
gene id: 161896:UL81_RS01700
uniprot id: A0A0F6QVE8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS05005
gene id: 161896:UL81_RS05005
uniprot id: A0A0F6QY17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS06545
gene id: 161896:UL81_RS06545
uniprot id: A0A0F6QX11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

161896:UL81 RS02045
gene id: 161896:UL81_RS02045
uniprot id: A0A0F6QX22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS04880
gene id: 161896:UL81_RS04880
uniprot id: A0A0F6QVQ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

161896:UL81 RS00590
gene id: 161896:UL81_RS00590
uniprot id: A0A0F6TAC1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

161896:UL81 RS11115
gene id: 161896:UL81_RS11115
uniprot id: A0A0F6R021
names: Similarity
messages: Belongs to the UPF0371 family.

161896:UL81 RS05150
gene id: 161896:UL81_RS05150
uniprot id: A0A0F6QY33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS02105
gene id: 161896:UL81_RS02105
uniprot id: A0A0F6TAN7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161896:UL81 RS09570
gene id: 161896:UL81_RS09570
uniprot id: A0A0F6QY26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

161896:UL81 RS09450
gene id: 161896:UL81_RS09450
uniprot id: A0A0F6TBF5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

161896:UL81 RS07735
gene id: 161896:UL81_RS07735
uniprot id: A0A0F6TBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

161896:UL81 RS00925
gene id: 161896:UL81_RS00925
uniprot id: A0A0F6QV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Membrane

161896:UL81 RS01915
gene id: 161896:UL81_RS01915
uniprot id: A0A0F6QX09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

161896:UL81 RS08090
gene id: 161896:UL81_RS08090
uniprot id: A0A0F6TB72
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS00395
gene id: 161896:UL81_RS00395
uniprot id: A0A0F6QWF8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

161896:UL81 RS10335
gene id: 161896:UL81_RS10335
uniprot id: A0A0F6TCG5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

161896:UL81 RS06595
gene id: 161896:UL81_RS06595
uniprot id: A0A0F6QX18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

161896:UL81 RS10845
gene id: 161896:UL81_RS10845
uniprot id: A0A0F6QXR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS04580
gene id: 161896:UL81_RS04580
uniprot id: A0A0F6QXX9
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS05370
gene id: 161896:UL81_RS05370
uniprot id: A0A0F6QWM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161896:UL81 RS06225
gene id: 161896:UL81_RS06225
uniprot id: A0A0F6TB77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

161896:UL81 RS11040
gene id: 161896:UL81_RS11040
uniprot id: A0A0F6QXT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

161896:UL81 RS09065
gene id: 161896:UL81_RS09065
uniprot id: A0A0F6TBT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

161896:UL81 RS04850
gene id: 161896:UL81_RS04850
uniprot id: A0A0F6TAD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

161896:UL81 RS04655
gene id: 161896:UL81_RS04655
uniprot id: A0A0F6QXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

161896:UL81 RS02700
gene id: 161896:UL81_RS02700
uniprot id: A0A0F6QVR4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

161896:UL81 RS10120
gene id: 161896:UL81_RS10120
uniprot id: A0A0F6QZR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

161896:UL81 RS07730
gene id: 161896:UL81_RS07730
uniprot id: A0A0F6QXF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

161896:UL81 RS08335
gene id: 161896:UL81_RS08335
uniprot id: A0A0F6TB60
names: Similarity
messages: Belongs to the Fur family.

161896:UL81 RS10225
gene id: 161896:UL81_RS10225
uniprot id: A0A0F6TC56
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS09985
gene id: 161896:UL81_RS09985
uniprot id: A0A0F6QY67
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

161896:UL81 RS08540
gene id: 161896:UL81_RS08540
uniprot id: A0A0F6QXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

161896:UL81 RS05090
gene id: 161896:UL81_RS05090
uniprot id: A0A0F6TAF4
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS08760
gene id: 161896:UL81_RS08760
uniprot id: A0A0F6TB91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

161896:UL81 RS03435
gene id: 161896:UL81_RS03435
uniprot id: A0A0F6TAX2
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

161896:UL81 RS03225
gene id: 161896:UL81_RS03225
uniprot id: A0A0F6TAV7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

161896:UL81 RS02410
gene id: 161896:UL81_RS02410
uniprot id: A0A0F6QUW5
names: Similarity
messages: Belongs to the citrate synthase family.

161896:UL81 RS09800
gene id: 161896:UL81_RS09800
uniprot id: A0A0F6TC24
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

161896:UL81 RS06895
gene id: 161896:UL81_RS06895
uniprot id: A0A0F6QYQ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161896:UL81 RS01370
gene id: 161896:UL81_RS01370
uniprot id: A0A0F6QVA8
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01195
gene id: 161896:UL81_RS01195
uniprot id: A0A0F6T9K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

161896:UL81 RS04040
gene id: 161896:UL81_RS04040
uniprot id: A0A0F6QXQ1
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS06075
gene id: 161896:UL81_RS06075
uniprot id: A0A0F6TB51
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

161896:UL81 RS10530
gene id: 161896:UL81_RS10530
uniprot id: A0A0F6TCI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

161896:UL81 RS05735
gene id: 161896:UL81_RS05735
uniprot id: A0A0F6TAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

161896:UL81 RS08230
gene id: 161896:UL81_RS08230
uniprot id: A0A0F6QWV2
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

161896:UL81 RS03505
gene id: 161896:UL81_RS03505
uniprot id: A0A0F6QXI0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

161896:UL81 RS11230
gene id: 161896:UL81_RS11230
uniprot id: A0A0F6TCN6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

161896:UL81 RS08160
gene id: 161896:UL81_RS08160
uniprot id: A0A0F6TBM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

161896:UL81 RS05565
gene id: 161896:UL81_RS05565
uniprot id: A0A0F6QY78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS01795
gene id: 161896:UL81_RS01795
uniprot id: A0A0F6TAL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

161896:UL81 RS08415
gene id: 161896:UL81_RS08415
uniprot id: A0A0F6QZ62
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS07365
gene id: 161896:UL81_RS07365
uniprot id: A0A0F6QWK1
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS07085
gene id: 161896:UL81_RS07085
uniprot id: A0A0F6TAW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

161896:UL81 RS06870
gene id: 161896:UL81_RS06870
uniprot id: A0A0F6QYQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

161896:UL81 RS03665
gene id: 161896:UL81_RS03665
uniprot id: A0A0F6QXK1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

161896:UL81 RS09895
gene id: 161896:UL81_RS09895
uniprot id: A0A0F6QY55
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

161896:UL81 RS04300
gene id: 161896:UL81_RS04300
uniprot id: A0A0F6TA86
names: Similarity
messages: Belongs to the FBPase class 2 family.

161896:UL81 RS01810
gene id: 161896:UL81_RS01810
uniprot id: A0A0F6QUQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

161896:UL81 RS05520
gene id: 161896:UL81_RS05520
uniprot id: A0A0F6TB17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

161896:UL81 RS08145
gene id: 161896:UL81_RS08145
uniprot id: A0A0F6TB75
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

161896:UL81 RS05690
gene id: 161896:UL81_RS05690
uniprot id: A0A0F6TB19
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

161896:UL81 RS08845
gene id: 161896:UL81_RS08845
uniprot id: A0A0F6TBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161896:UL81 RS02965
gene id: 161896:UL81_RS02965
uniprot id: A0A0F6QXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161896:UL81 RS03725
gene id: 161896:UL81_RS03725
uniprot id: A0A0F6QW32
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

161896:UL81 RS00370
gene id: 161896:UL81_RS00370
uniprot id: A0A0F6QWF3
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

161896:UL81 RS03040
gene id: 161896:UL81_RS03040
uniprot id: A0A0F6QXC0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

161896:UL81 RS07805
gene id: 161896:UL81_RS07805
uniprot id: A0A0F6QXG2
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

161896:UL81 RS05145
gene id: 161896:UL81_RS05145
uniprot id: A0A0F6QVT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

161896:UL81 RS02075
gene id: 161896:UL81_RS02075
uniprot id: A0A0F6T9S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

161896:UL81 RS08755
gene id: 161896:UL81_RS08755
uniprot id: A0A0F6QZA5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

161896:UL81 RS08685
gene id: 161896:UL81_RS08685
uniprot id: A0A0F6TBT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

161896:UL81 RS02620
gene id: 161896:UL81_RS02620
uniprot id: A0A0F6QX76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161896:UL81 RS00920
gene id: 161896:UL81_RS00920
uniprot id: A0A0F6TAE6
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

161896:UL81 RS00860
gene id: 161896:UL81_RS00860
uniprot id: A0A0F6QUC3
names: Similarity
messages: Belongs to the catalase family.

161896:UL81 RS08155
gene id: 161896:UL81_RS08155
uniprot id: A0A0F6QZ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

161896:UL81 RS10410
gene id: 161896:UL81_RS10410
uniprot id: A0A0F6QYB6
names: Similarity
messages: Belongs to the universal stress protein A family.

161896:UL81 RS02480
gene id: 161896:UL81_RS02480
uniprot id: A0A0F6QVN9
names: Similarity
messages: Belongs to the AccD/PCCB family.

161896:UL81 RS01870
gene id: 161896:UL81_RS01870
uniprot id: A0A0F6TAA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

161896:UL81 RS00760
gene id: 161896:UL81_RS00760
uniprot id: A0A0F6QWJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

161896:UL81 RS02895
gene id: 161896:UL81_RS02895
uniprot id: A0A0F6T9Y0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161896:UL81 RS01300
gene id: 161896:UL81_RS01300
uniprot id: A0A0F6TA67
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

161896:UL81 RS10010
gene id: 161896:UL81_RS10010
uniprot id: A0A0F6TC12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

161896:UL81 RS08765
gene id: 161896:UL81_RS08765
uniprot id: A0A0F6QXS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

161896:UL81 RS07180
gene id: 161896:UL81_RS07180
uniprot id: A0A0F6QX93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

161896:UL81 RS11315
gene id: 161896:UL81_RS11315
uniprot id: A0A0F6R049
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

161896:UL81 RS08400
gene id: 161896:UL81_RS08400
uniprot id: A0A0F6QXN0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

161896:UL81 RS04225
gene id: 161896:UL81_RS04225
uniprot id: A0A0F6TA65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS01315
gene id: 161896:UL81_RS01315
uniprot id: A0A0F6T9L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS06005
gene id: 161896:UL81_RS06005
uniprot id: A0A0F6QYD3
names: Similarity
messages: Belongs to the UPF0098 family.

161896:UL81 RS05530
gene id: 161896:UL81_RS05530
uniprot id: A0A0F6TAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

161896:UL81 RS07630
gene id: 161896:UL81_RS07630
uniprot id: A0A0F6QXE1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

161896:UL81 RS04130
gene id: 161896:UL81_RS04130
uniprot id: A0A0F6TB30
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

161896:UL81 RS01845
gene id: 161896:UL81_RS01845
uniprot id: A0A0F6TA84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

161896:UL81 RS01235
gene id: 161896:UL81_RS01235
uniprot id: A0A0F6QWR3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

161896:UL81 RS07375
gene id: 161896:UL81_RS07375
uniprot id: A0A0F6TBV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

161896:UL81 RS01085
gene id: 161896:UL81_RS01085
uniprot id: A0A0F6QUF2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

161896:UL81 RS03030
gene id: 161896:UL81_RS03030
uniprot id: A0A0F6TAG9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

161896:UL81 RS09575
gene id: 161896:UL81_RS09575
uniprot id: A0A0F6TBG8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

161896:UL81 RS07570
gene id: 161896:UL81_RS07570
uniprot id: A0A0F6QYW8
names: Similarity
messages: Belongs to the IMPACT family.

161896:UL81 RS00680
gene id: 161896:UL81_RS00680
uniprot id: A0A0F6QWJ0
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01455
gene id: 161896:UL81_RS01455
uniprot id: A0A0F6TA59
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

161896:UL81 RS05440
gene id: 161896:UL81_RS05440
uniprot id: A0A0F6QY62
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01110
gene id: 161896:UL81_RS01110
uniprot id: A0A0F6QUF6
names: Similarity
messages: Belongs to the peptidase M1 family.

161896:UL81 RS07025
gene id: 161896:UL81_RS07025
uniprot id: A0A0F6TAW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS06210
gene id: 161896:UL81_RS06210
uniprot id: A0A0F6QYG0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

161896:UL81 RS11380
gene id: 161896:UL81_RS11380
uniprot id: A0A0F6TBS7
names: Similarity
messages: Belongs to the ParB family.

161896:UL81 RS03640
gene id: 161896:UL81_RS03640
uniprot id: A0A0F6QXJ7
names: Similarity
messages: Belongs to the FPG family.

161896:UL81 RS02360
gene id: 161896:UL81_RS02360
uniprot id: A0A0F6QUW0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

161896:UL81 RS10315
gene id: 161896:UL81_RS10315
uniprot id: A0A0F6QXK3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161896:UL81 RS04945
gene id: 161896:UL81_RS04945
uniprot id: A0A0F6QWI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

161896:UL81 RS02230
gene id: 161896:UL81_RS02230
uniprot id: A0A0F6TAP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

161896:UL81 RS08235
gene id: 161896:UL81_RS08235
uniprot id: A0A0F6QZ39
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

161896:UL81 RS08225
gene id: 161896:UL81_RS08225
uniprot id: A0A0F6TBN0
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS00075
gene id: 161896:UL81_RS00075
uniprot id: A0A0F6TA42
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

161896:UL81 RS07030
gene id: 161896:UL81_RS07030
uniprot id: A0A0F6QX81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

161896:UL81 RS10775
gene id: 161896:UL81_RS10775
uniprot id: A0A0F6TCK1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

161896:UL81 RS07345
gene id: 161896:UL81_RS07345
uniprot id: A0A0F6QYU7
names: Similarity
messages: Belongs to the P(II) protein family.

161896:UL81 RS01715
gene id: 161896:UL81_RS01715
uniprot id: A0A0F6QWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

161896:UL81 RS03060
gene id: 161896:UL81_RS03060
uniprot id: A0A0F6QXC3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

161896:UL81 RS01920
gene id: 161896:UL81_RS01920
uniprot id: A0A0F6TAM4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161896:UL81 RS05320
gene id: 161896:UL81_RS05320
uniprot id: A0A0F6QWM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

161896:UL81 RS02265
gene id: 161896:UL81_RS02265
uniprot id: A0A0F6QX45
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

161896:UL81 RS10460
gene id: 161896:UL81_RS10460
uniprot id: A0A0F6QYC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

161896:UL81 RS03985
gene id: 161896:UL81_RS03985
uniprot id: A0A0F6QVD6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

161896:UL81 RS01600
gene id: 161896:UL81_RS01600
uniprot id: A0A0F6QVD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

161896:UL81 RS10340
gene id: 161896:UL81_RS10340
uniprot id: A0A0F6QXK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS06485
gene id: 161896:UL81_RS06485
uniprot id: A0A0F6QYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

161896:UL81 RS08325
gene id: 161896:UL81_RS08325
uniprot id: A0A0F6TBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

161896:UL81 RS03320
gene id: 161896:UL81_RS03320
uniprot id: A0A0F6TA00
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

161896:UL81 RS07835
gene id: 161896:UL81_RS07835
uniprot id: A0A0F6TB23
names: Similarity
messages: Belongs to the peptidase C40 family.

161896:UL81 RS10060
gene id: 161896:UL81_RS10060
uniprot id: A0A0F6TBK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

161896:UL81 RS02305
gene id: 161896:UL81_RS02305
uniprot id: A0A0F6TAE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

161896:UL81 RS04905
gene id: 161896:UL81_RS04905
uniprot id: A0A0F6QVQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

161896:UL81 RS07910
gene id: 161896:UL81_RS07910
uniprot id: A0A0F6TB58
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

161896:UL81 RS00005
gene id: 161896:UL81_RS00005
uniprot id: A0A0F6QWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

161896:UL81 RS05040
gene id: 161896:UL81_RS05040
uniprot id: A0A0F6TAW6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

161896:UL81 RS02320
gene id: 161896:UL81_RS02320
uniprot id: A0A0F6T9T9
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS09335
gene id: 161896:UL81_RS09335
uniprot id: A0A0F6QXY8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

161896:UL81 RS08850
gene id: 161896:UL81_RS08850
uniprot id: A0A0F6QXT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS04105
gene id: 161896:UL81_RS04105
uniprot id: A0A0F6TA73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

161896:UL81 RS02220
gene id: 161896:UL81_RS02220
uniprot id: A0A0F6TAA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

161896:UL81 RS09470
gene id: 161896:UL81_RS09470
uniprot id: A0A0F6QY16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

161896:UL81 RS02955
gene id: 161896:UL81_RS02955
uniprot id: A0A0F6T9Y4
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

161896:UL81 RS03070
gene id: 161896:UL81_RS03070
uniprot id: A0A0F6QVV9
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

161896:UL81 RS00940
gene id: 161896:UL81_RS00940
uniprot id: A0A0F6QWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS09060
gene id: 161896:UL81_RS09060
uniprot id: A0A0F6QZE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

161896:UL81 RS09475
gene id: 161896:UL81_RS09475
uniprot id: A0A0F6TC97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

161896:UL81 RS10150
gene id: 161896:UL81_RS10150
uniprot id: A0A0F6TCE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

161896:UL81 RS07275
gene id: 161896:UL81_RS07275
uniprot id: A0A0F6TAY2
names: Similarity
messages: Belongs to the UPF0102 family.

161896:UL81 RS05045
gene id: 161896:UL81_RS05045
uniprot id: A0A0F6QVS5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

161896:UL81 RS06550
gene id: 161896:UL81_RS06550
uniprot id: A0A0F6TAT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

161896:UL81 RS05925
gene id: 161896:UL81_RS05925
uniprot id: A0A0F6TAK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

161896:UL81 RS11215
gene id: 161896:UL81_RS11215
uniprot id: A0A0F6R035
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161896:UL81 RS03620
gene id: 161896:UL81_RS03620
uniprot id: A0A0F6TAL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS00450
gene id: 161896:UL81_RS00450
uniprot id: A0A0F6T9Z2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161896:UL81 RS08490
gene id: 161896:UL81_RS08490
uniprot id: A0A0F6TC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS02090
gene id: 161896:UL81_RS02090
uniprot id: A0A0F6QUT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

161896:UL81 RS05855
gene id: 161896:UL81_RS05855
uniprot id: A0A0F6QW14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

161896:UL81 RS01965
gene id: 161896:UL81_RS01965
uniprot id: A0A0F6QX14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161896:UL81 RS03710
gene id: 161896:UL81_RS03710
uniprot id: A0A0F6QVA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

161896:UL81 RS03350
gene id: 161896:UL81_RS03350
uniprot id: A0A0F6QVZ2
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

161896:UL81 RS06195
gene id: 161896:UL81_RS06195
uniprot id: A0A0F6QWX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

161896:UL81 RS11050
gene id: 161896:UL81_RS11050
uniprot id: A0A0F6TCM0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

161896:UL81 RS10660
gene id: 161896:UL81_RS10660
uniprot id: A0A0F6QYE7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

161896:UL81 RS05420
gene id: 161896:UL81_RS05420
uniprot id: A0A0F6TAI1
names: Similarity
messages: Belongs to the universal stress protein A family.

161896:UL81 RS05890
gene id: 161896:UL81_RS05890
uniprot id: A0A0F6TB35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

161896:UL81 RS01190
gene id: 161896:UL81_RS01190
uniprot id: A0A0F6QWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

161896:UL81 RS06115
gene id: 161896:UL81_RS06115
uniprot id: A0A0F6TAL8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

161896:UL81 RS07895
gene id: 161896:UL81_RS07895
uniprot id: A0A0F6QYZ8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

161896:UL81 RS01565
gene id: 161896:UL81_RS01565
uniprot id: A0A0F6QWV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

161896:UL81 RS07405
gene id: 161896:UL81_RS07405
uniprot id: A0A0F6QXB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

161896:UL81 RS08590
gene id: 161896:UL81_RS08590
uniprot id: A0A0F6QXQ5
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS10480
gene id: 161896:UL81_RS10480
uniprot id: A0A0F6TC72
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS03860
gene id: 161896:UL81_RS03860
uniprot id: A0A0F6QVC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

161896:UL81 RS02820
gene id: 161896:UL81_RS02820
uniprot id: A0A0F6T9W9
names: Subcellular Location Annotation
messages: Membrane

161896:UL81 RS01065
gene id: 161896:UL81_RS01065
uniprot id: A0A0F6QWP0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

161896:UL81 RS07850
gene id: 161896:UL81_RS07850
uniprot id: A0A0F6TB53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

161896:UL81 RS00470
gene id: 161896:UL81_RS00470
uniprot id: A0A0F6QWG7
names: Similarity
messages: Belongs to the UPF0145 family.

161896:UL81 RS02100
gene id: 161896:UL81_RS02100
uniprot id: A0A0F6QVJ5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

161896:UL81 RS02660
gene id: 161896:UL81_RS02660
uniprot id: A0A0F6QUZ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

161896:UL81 RS07840
gene id: 161896:UL81_RS07840
uniprot id: A0A0F6QWQ7
names: Similarity
messages: Belongs to the peptidase C40 family.

161896:UL81 RS03690
gene id: 161896:UL81_RS03690
uniprot id: A0A0F6QXK4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

161896:UL81 RS02650
gene id: 161896:UL81_RS02650
uniprot id: A0A0F6QVQ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161896:UL81 RS05525
gene id: 161896:UL81_RS05525
uniprot id: A0A0F6QWP7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

161896:UL81 RS03310
gene id: 161896:UL81_RS03310
uniprot id: A0A0F6QV64
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

161896:UL81 RS08935
gene id: 161896:UL81_RS08935
uniprot id: A0A0F6TC66
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

161896:UL81 RS05315
gene id: 161896:UL81_RS05315
uniprot id: A0A0F6TBB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

161896:UL81 RS04325
gene id: 161896:UL81_RS04325
uniprot id: A0A0F6TB45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

161896:UL81 RS01550
gene id: 161896:UL81_RS01550
uniprot id: A0A0F6QVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

161896:UL81 RS07310
gene id: 161896:UL81_RS07310
uniprot id: A0A0F6TBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

161896:UL81 RS03715
gene id: 161896:UL81_RS03715
uniprot id: A0A0F6QXK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

161896:UL81 RS07245
gene id: 161896:UL81_RS07245
uniprot id: A0A0F6QYU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

161896:UL81 RS01655
gene id: 161896:UL81_RS01655
uniprot id: A0A0F6TA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161896:UL81 RS09555
gene id: 161896:UL81_RS09555
uniprot id: A0A0F6QXB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.