1618207:UM93 RS09690
gene id: 1618207:UM93_RS09690
uniprot id: A0A0D4BZY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1618207:UM93 RS13450
gene id: 1618207:UM93_RS13450
uniprot id: A0A0D4C115
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS15780
gene id: 1618207:UM93_RS15780
uniprot id: A0A0D4C215
names: Similarity
messages: Belongs to the malate synthase family.

1618207:UM93 RS04315
gene id: 1618207:UM93_RS04315
uniprot id: A0A0D4BX75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS10475
gene id: 1618207:UM93_RS10475
uniprot id: A0A0D4C094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1618207:UM93 RS02055
gene id: 1618207:UM93_RS02055
uniprot id: A0A0D4BWY1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1618207:UM93 RS01725
gene id: 1618207:UM93_RS01725
uniprot id: A0A0D4BWA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1618207:UM93 RS03530
gene id: 1618207:UM93_RS03530
uniprot id: A0A0D4BXF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1618207:UM93 RS11035
gene id: 1618207:UM93_RS11035
uniprot id: A0A0D4C0H0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1618207:UM93 RS06500
gene id: 1618207:UM93_RS06500
uniprot id: A0A0D4BYT1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS03830
gene id: 1618207:UM93_RS03830
uniprot id: A0A0D4BWL4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1618207:UM93 RS06540
gene id: 1618207:UM93_RS06540
uniprot id: A0A0D4BXT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08845
gene id: 1618207:UM93_RS08845
uniprot id: A0A0D4BZ44
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09460
gene id: 1618207:UM93_RS09460
uniprot id: A0A0D4BZE3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1618207:UM93 RS00460
gene id: 1618207:UM93_RS00460
uniprot id: A0A0D4BWA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1618207:UM93 RS05810
gene id: 1618207:UM93_RS05810
uniprot id: A0A0D4BYH7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1618207:UM93 RS08650
gene id: 1618207:UM93_RS08650
uniprot id: A0A0D4BZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS07995
gene id: 1618207:UM93_RS07995
uniprot id: A0A0D4BYQ7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1618207:UM93 RS03480
gene id: 1618207:UM93_RS03480
uniprot id: A0A0D4BWH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1618207:UM93 RS00675
gene id: 1618207:UM93_RS00675
uniprot id: A0A0D4BWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1618207:UM93 RS03130
gene id: 1618207:UM93_RS03130
uniprot id: A0A0D4BXC7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1618207:UM93 RS01035
gene id: 1618207:UM93_RS01035
uniprot id: A0A0D4BWI0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS14135
gene id: 1618207:UM93_RS14135
uniprot id: A0A0D4C1U6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1618207:UM93 RS09675
gene id: 1618207:UM93_RS09675
uniprot id: A0A0D4BZ46
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1618207:UM93 RS06415
gene id: 1618207:UM93_RS06415
uniprot id: A0A0D4BXR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08110
gene id: 1618207:UM93_RS08110
uniprot id: A0A0D4BYU2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS16205
gene id: 1618207:UM93_RS16205
uniprot id: A0A0D4C269
names: Similarity
messages: Belongs to the FemABX family.

1618207:UM93 RS04920
gene id: 1618207:UM93_RS04920
uniprot id: A0A0D4BXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1618207:UM93 RS11765
gene id: 1618207:UM93_RS11765
uniprot id: A0A0D4C035
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1618207:UM93 RS05100
gene id: 1618207:UM93_RS05100
uniprot id: A0A0D4BY58
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

1618207:UM93 RS04425
gene id: 1618207:UM93_RS04425
uniprot id: A0A0D4BX93
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS04295
gene id: 1618207:UM93_RS04295
uniprot id: A0A0D4BX71
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS01420
gene id: 1618207:UM93_RS01420
uniprot id: A0A0D4BW54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1618207:UM93 RS06890
gene id: 1618207:UM93_RS06890
uniprot id: A0A0D4BYW9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1618207:UM93 RS10345
gene id: 1618207:UM93_RS10345
uniprot id: A0A0D4BZS3
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09915
gene id: 1618207:UM93_RS09915
uniprot id: A0A0D4BZ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1618207:UM93 RS15795
gene id: 1618207:UM93_RS15795
uniprot id: A0A0D4C1P0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1618207:UM93 RS14205
gene id: 1618207:UM93_RS14205
uniprot id: A0A0D4C1V7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1618207:UM93 RS06475
gene id: 1618207:UM93_RS06475
uniprot id: A0A0D4BXS3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1618207:UM93 RS12270
gene id: 1618207:UM93_RS12270
uniprot id: A0A0D4C116
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1618207:UM93 RS12595
gene id: 1618207:UM93_RS12595
uniprot id: A0A0D4C0D1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS03735
gene id: 1618207:UM93_RS03735
uniprot id: A0A0D4BWZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1618207:UM93 RS00640
gene id: 1618207:UM93_RS00640
uniprot id: A0A0D4BVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1618207:UM93 RS14840
gene id: 1618207:UM93_RS14840
uniprot id: A0A0D4C1H6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1618207:UM93 RS04015
gene id: 1618207:UM93_RS04015
uniprot id: A0A0D4BWP4
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS11545
gene id: 1618207:UM93_RS11545
uniprot id: A0A0D4C083
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1618207:UM93 RS14835
gene id: 1618207:UM93_RS14835
uniprot id: A0A0D4C183
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1618207:UM93 RS10635
gene id: 1618207:UM93_RS10635
uniprot id: A0A0D4C0G1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1618207:UM93 RS06000
gene id: 1618207:UM93_RS06000
uniprot id: A0A0D4BXZ6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1618207:UM93 RS01245
gene id: 1618207:UM93_RS01245
uniprot id: A0A0D4BWN0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1618207:UM93 RS08240
gene id: 1618207:UM93_RS08240
uniprot id: A0A0D4BZF3
names: Similarity
messages: Belongs to the peptidase S1C family.

1618207:UM93 RS05655
gene id: 1618207:UM93_RS05655
uniprot id: A0A0D4BXU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1618207:UM93 RS06835
gene id: 1618207:UM93_RS06835
uniprot id: A0A0D4BYA9
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS04390
gene id: 1618207:UM93_RS04390
uniprot id: A0A0D4BX87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1618207:UM93 RS01435
gene id: 1618207:UM93_RS01435
uniprot id: A0A0D4BWR0
names: Similarity
messages: Belongs to the YciI family.

1618207:UM93 RS05460
gene id: 1618207:UM93_RS05460
uniprot id: A0A0D4BXR2
names: Similarity
messages: Belongs to the CFA/CMAS family.

1618207:UM93 RS07150
gene id: 1618207:UM93_RS07150
uniprot id: A0A0D4BY04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1618207:UM93 RS05140
gene id: 1618207:UM93_RS05140
uniprot id: A0A0D4BY91
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1618207:UM93 RS09435
gene id: 1618207:UM93_RS09435
uniprot id: A0A0D4BZV5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1618207:UM93 RS12485
gene id: 1618207:UM93_RS12485
uniprot id: A0A0D4C0L7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1618207:UM93 RS14200
gene id: 1618207:UM93_RS14200
uniprot id: A0A0D4C1R4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1618207:UM93 RS08480
gene id: 1618207:UM93_RS08480
uniprot id: A0A0D4BZI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1618207:UM93 RS01845
gene id: 1618207:UM93_RS01845
uniprot id: A0A0D4BWW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1618207:UM93 RS01945
gene id: 1618207:UM93_RS01945
uniprot id: A0A0D4BWC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1618207:UM93 RS10275
gene id: 1618207:UM93_RS10275
uniprot id: A0A0D4BZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1618207:UM93 RS13100
gene id: 1618207:UM93_RS13100
uniprot id: A0A0D4C1D2
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

1618207:UM93 RS10040
gene id: 1618207:UM93_RS10040
uniprot id: A0A0D4C040
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1618207:UM93 RS15785
gene id: 1618207:UM93_RS15785
uniprot id: A0A0D4C2G5
names: Cofactor
messages: Can also use Mn(2+) ion.

1618207:UM93 RS04430
gene id: 1618207:UM93_RS04430
uniprot id: A0A0D4BXT7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1618207:UM93 RS15810
gene id: 1618207:UM93_RS15810
uniprot id: A0A0D4C223
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1618207:UM93 RS05755
gene id: 1618207:UM93_RS05755
uniprot id: A0A0D4C2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1618207:UM93 RS16775
gene id: 1618207:UM93_RS16775
uniprot id: A0A0D4C210
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS03920
gene id: 1618207:UM93_RS03920
uniprot id: A0A0D4BXK9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1618207:UM93 RS10355
gene id: 1618207:UM93_RS10355
uniprot id: A0A0D4C0C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1618207:UM93 RS05070
gene id: 1618207:UM93_RS05070
uniprot id: A0A0D4BXM2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1618207:UM93 RS06340
gene id: 1618207:UM93_RS06340
uniprot id: A0A0D4BY21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1618207:UM93 RS09270
gene id: 1618207:UM93_RS09270
uniprot id: A0A0D4BZT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1618207:UM93 RS01255
gene id: 1618207:UM93_RS01255
uniprot id: A0A0D4BVR2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1618207:UM93 RS08020
gene id: 1618207:UM93_RS08020
uniprot id: A0A0D4BZC7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS11950
gene id: 1618207:UM93_RS11950
uniprot id: A0A0D4C3C9
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09550
gene id: 1618207:UM93_RS09550
uniprot id: A0A0D4BZX3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1618207:UM93 RS16120
gene id: 1618207:UM93_RS16120
uniprot id: A0A0D4C2N6
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1618207:UM93 RS11890
gene id: 1618207:UM93_RS11890
uniprot id: A0A0D4C054
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS01745
gene id: 1618207:UM93_RS01745
uniprot id: A0A0D4BVX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS09165
gene id: 1618207:UM93_RS09165
uniprot id: A0A0D4BZA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1618207:UM93 RS15000
gene id: 1618207:UM93_RS15000
uniprot id: A0A0D4C1M9
names: Similarity
messages: Belongs to the UPF0045 family.

1618207:UM93 RS16025
gene id: 1618207:UM93_RS16025
uniprot id: A0A0D4C3G5
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1618207:UM93 RS05620
gene id: 1618207:UM93_RS05620
uniprot id: A0A0D4BXF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1618207:UM93 RS09415
gene id: 1618207:UM93_RS09415
uniprot id: A0A0D4BZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1618207:UM93 RS12650
gene id: 1618207:UM93_RS12650
uniprot id: A0A0D4C0P1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1618207:UM93 RS13505
gene id: 1618207:UM93_RS13505
uniprot id: A0A0D4C0Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1618207:UM93 RS06735
gene id: 1618207:UM93_RS06735
uniprot id: A0A0D4BYS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1618207:UM93 RS04815
gene id: 1618207:UM93_RS04815
uniprot id: A0A0D4BY15
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1618207:UM93 RS04875
gene id: 1618207:UM93_RS04875
uniprot id: A0A0D4BY23
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1618207:UM93 RS06790
gene id: 1618207:UM93_RS06790
uniprot id: A0A0D4BXW2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1618207:UM93 RS13515
gene id: 1618207:UM93_RS13515
uniprot id: A0A0D4C1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1618207:UM93 RS10975
gene id: 1618207:UM93_RS10975
uniprot id: A0A0D4C3F7
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS03325
gene id: 1618207:UM93_RS03325
uniprot id: A0A0D4BWF4
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1618207:UM93 RS04725
gene id: 1618207:UM93_RS04725
uniprot id: A0A0D4BXD4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS09160
gene id: 1618207:UM93_RS09160
uniprot id: A0A0D4BZ86
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1618207:UM93 RS16770
gene id: 1618207:UM93_RS16770
uniprot id: A0A0D4C2X1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS01105
gene id: 1618207:UM93_RS01105
uniprot id: A0A0D4BW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1618207:UM93 RS02065
gene id: 1618207:UM93_RS02065
uniprot id: A0A0D4BW06
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1618207:UM93 RS10185
gene id: 1618207:UM93_RS10185
uniprot id: A0A0D4C064
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1618207:UM93 RS11475
gene id: 1618207:UM93_RS11475
uniprot id: A0A0D4C076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1618207:UM93 RS07170
gene id: 1618207:UM93_RS07170
uniprot id: A0A0D4BYX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1618207:UM93 RS00835
gene id: 1618207:UM93_RS00835
uniprot id: A0A0D4BVI4
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09020
gene id: 1618207:UM93_RS09020
uniprot id: A0A0D4BZU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS10255
gene id: 1618207:UM93_RS10255
uniprot id: A0A0D4C373
names: Similarity
messages: Belongs to the YciI family.

1618207:UM93 RS02840
gene id: 1618207:UM93_RS02840
uniprot id: A0A0D4BWL2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS00865
gene id: 1618207:UM93_RS00865
uniprot id: A0A0D4BWF7
names: Similarity
messages: Belongs to the UPF0145 family.

1618207:UM93 RS00860
gene id: 1618207:UM93_RS00860
uniprot id: A0A0D4C2C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1618207:UM93 RS12305
gene id: 1618207:UM93_RS12305
uniprot id: A0A0D4C097
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1618207:UM93 RS10725
gene id: 1618207:UM93_RS10725
uniprot id: A0A0D4BZI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1618207:UM93 RS15295
gene id: 1618207:UM93_RS15295
uniprot id: A0A0D4C1V3
names: Similarity
messages: Belongs to the thioesterase family.

1618207:UM93 RS00830
gene id: 1618207:UM93_RS00830
uniprot id: A0A0D4BWF2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1618207:UM93 RS01275
gene id: 1618207:UM93_RS01275
uniprot id: A0A0D4BWN5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS02895
gene id: 1618207:UM93_RS02895
uniprot id: A0A0D4BW85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1618207:UM93 RS04010
gene id: 1618207:UM93_RS04010
uniprot id: A0A0D4BXN6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1618207:UM93 RS00160
gene id: 1618207:UM93_RS00160
uniprot id: A0A0D4BVM4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1618207:UM93 RS15420
gene id: 1618207:UM93_RS15420
uniprot id: A0A0D4C1S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1618207:UM93 RS06640
gene id: 1618207:UM93_RS06640
uniprot id: A0A0D4BXU4
names: Similarity
messages: Belongs to the MQO family.

1618207:UM93 RS08685
gene id: 1618207:UM93_RS08685
uniprot id: A0A0D4BZP7
names: Similarity
messages: Belongs to the citrate synthase family.

1618207:UM93 RS08170
gene id: 1618207:UM93_RS08170
uniprot id: A0A0D4BZE6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1618207:UM93 RS08770
gene id: 1618207:UM93_RS08770
uniprot id: A0A0D4BZR3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1618207:UM93 RS11725
gene id: 1618207:UM93_RS11725
uniprot id: A0A0D4C030
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS00525
gene id: 1618207:UM93_RS00525
uniprot id: A0A0D4BVR1
names: Similarity
messages: Belongs to the FBPase class 2 family.

1618207:UM93 RS09695
gene id: 1618207:UM93_RS09695
uniprot id: A0A0D4C037
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1618207:UM93 RS00560
gene id: 1618207:UM93_RS00560
uniprot id: A0A0D4BVR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS16225
gene id: 1618207:UM93_RS16225
uniprot id: A0A0D4C1T2
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS10140
gene id: 1618207:UM93_RS10140
uniprot id: A0A0D4C3S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1618207:UM93 RS10005
gene id: 1618207:UM93_RS10005
uniprot id: A0A0D4BZM3
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09635
gene id: 1618207:UM93_RS09635
uniprot id: A0A0D4C028
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1618207:UM93 RS01590
gene id: 1618207:UM93_RS01590
uniprot id: A0A0D4C2F2
names: Similarity
messages: Belongs to the peptidase M16 family.

1618207:UM93 RS00550
gene id: 1618207:UM93_RS00550
uniprot id: A0A0D4BVF0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1618207:UM93 RS06775
gene id: 1618207:UM93_RS06775
uniprot id: A0A0D4BYT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1618207:UM93 RS10455
gene id: 1618207:UM93_RS10455
uniprot id: A0A0D4C0D7
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS06085
gene id: 1618207:UM93_RS06085
uniprot id: A0A0D4BY06
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1618207:UM93 RS04800
gene id: 1618207:UM93_RS04800
uniprot id: A0A0D4BXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1618207:UM93 RS00130
gene id: 1618207:UM93_RS00130
uniprot id: A0A0D4C2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS06990
gene id: 1618207:UM93_RS06990
uniprot id: A0A0D4BYB3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1618207:UM93 RS03955
gene id: 1618207:UM93_RS03955
uniprot id: A0A0D4BXM6
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS06275
gene id: 1618207:UM93_RS06275
uniprot id: A0A0D4BXN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1618207:UM93 RS01125
gene id: 1618207:UM93_RS01125
uniprot id: A0A0D4BWK7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1618207:UM93 RS04765
gene id: 1618207:UM93_RS04765
uniprot id: A0A0D4BX26
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS09965
gene id: 1618207:UM93_RS09965
uniprot id: A0A0D4BZL8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1618207:UM93 RS10450
gene id: 1618207:UM93_RS10450
uniprot id: A0A0D4C091
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1618207:UM93 RS05030
gene id: 1618207:UM93_RS05030
uniprot id: A0A0D4BXK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1618207:UM93 RS12495
gene id: 1618207:UM93_RS12495
uniprot id: A0A0D4C150
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1618207:UM93 RS09480
gene id: 1618207:UM93_RS09480
uniprot id: A0A0D4BZD4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1618207:UM93 RS07885
gene id: 1618207:UM93_RS07885
uniprot id: A0A0D4BZA9
names: Similarity
messages: Belongs to the UPF0098 family.

1618207:UM93 RS09585
gene id: 1618207:UM93_RS09585
uniprot id: A0A0D4BZE5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1618207:UM93 RS06710
gene id: 1618207:UM93_RS06710
uniprot id: A0A0D4BXV4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1618207:UM93 RS12040
gene id: 1618207:UM93_RS12040
uniprot id: A0A0D4C0Y6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1618207:UM93 RS02050
gene id: 1618207:UM93_RS02050
uniprot id: A0A0D4BWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1618207:UM93 RS03515
gene id: 1618207:UM93_RS03515
uniprot id: A0A0D4BWH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1618207:UM93 RS13525
gene id: 1618207:UM93_RS13525
uniprot id: A0A0D4C0Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1618207:UM93 RS03845
gene id: 1618207:UM93_RS03845
uniprot id: A0A0D4BX09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1618207:UM93 RS06520
gene id: 1618207:UM93_RS06520
uniprot id: A0A0D4BY72
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1618207:UM93 RS04770
gene id: 1618207:UM93_RS04770
uniprot id: A0A0D4BXF8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS00445
gene id: 1618207:UM93_RS00445
uniprot id: A0A0D4BVQ9
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1618207:UM93 RS02570
gene id: 1618207:UM93_RS02570
uniprot id: A0A0D4BWJ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1618207:UM93 RS09240
gene id: 1618207:UM93_RS09240
uniprot id: A0A0D4BZS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1618207:UM93 RS05875
gene id: 1618207:UM93_RS05875
uniprot id: A0A0D4BYG1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1618207:UM93 RS15060
gene id: 1618207:UM93_RS15060
uniprot id: A0A0D4C245
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1618207:UM93 RS02285
gene id: 1618207:UM93_RS02285
uniprot id: A0A0D4BWG2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS16170
gene id: 1618207:UM93_RS16170
uniprot id: A0A0D4C4A4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1618207:UM93 RS16600
gene id: 1618207:UM93_RS16600
uniprot id: A0A0D4C2V0
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS13755
gene id: 1618207:UM93_RS13755
uniprot id: A0A0D4C1L2
names: Similarity
messages: Belongs to the DapA family.

1618207:UM93 RS11490
gene id: 1618207:UM93_RS11490
uniprot id: A0A0D4C0T0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1618207:UM93 RS03360
gene id: 1618207:UM93_RS03360
uniprot id: A0A0D4BXE5
names: Subcellular Location Annotation
messages: Cytoplasm

1618207:UM93 RS09190
gene id: 1618207:UM93_RS09190
uniprot id: A0A0D4BZ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1618207:UM93 RS11955
gene id: 1618207:UM93_RS11955
uniprot id: A0A0D4C3J2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS13915
gene id: 1618207:UM93_RS13915
uniprot id: A0A0D4C1N0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1618207:UM93 RS12230
gene id: 1618207:UM93_RS12230
uniprot id: A0A0D4C111
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1618207:UM93 RS00375
gene id: 1618207:UM93_RS00375
uniprot id: A0A0D4BVP8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1618207:UM93 RS13520
gene id: 1618207:UM93_RS13520
uniprot id: A0A0D4C1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1618207:UM93 RS10195
gene id: 1618207:UM93_RS10195
uniprot id: A0A0D4BZC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS14005
gene id: 1618207:UM93_RS14005
uniprot id: A0A0D4C1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1618207:UM93 RS02475
gene id: 1618207:UM93_RS02475
uniprot id: A0A0D4BWI6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1618207:UM93 RS07480
gene id: 1618207:UM93_RS07480
uniprot id: A0A0D4BY52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1618207:UM93 RS03580
gene id: 1618207:UM93_RS03580
uniprot id: A0A0D4BWI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1618207:UM93 RS01395
gene id: 1618207:UM93_RS01395
uniprot id: A0A0D4BWP2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1618207:UM93 RS12540
gene id: 1618207:UM93_RS12540
uniprot id: A0A0D4C0Q5
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1618207:UM93 RS15030
gene id: 1618207:UM93_RS15030
uniprot id: A0A0D4C239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1618207:UM93 RS11965
gene id: 1618207:UM93_RS11965
uniprot id: A0A0D4C0E5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1618207:UM93 RS07825
gene id: 1618207:UM93_RS07825
uniprot id: A0A0D4C3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1618207:UM93 RS07435
gene id: 1618207:UM93_RS07435
uniprot id: A0A0D4BZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1618207:UM93 RS11065
gene id: 1618207:UM93_RS11065
uniprot id: A0A0D4C016
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1618207:UM93 RS05600
gene id: 1618207:UM93_RS05600
uniprot id: A0A0D4BXU7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1618207:UM93 RS01490
gene id: 1618207:UM93_RS01490
uniprot id: A0A0D4BW65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS05675
gene id: 1618207:UM93_RS05675
uniprot id: A0A0D4BXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1618207:UM93 RS09790
gene id: 1618207:UM93_RS09790
uniprot id: A0A0D4BZ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS09615
gene id: 1618207:UM93_RS09615
uniprot id: A0A0D4BZE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1618207:UM93 RS01960
gene id: 1618207:UM93_RS01960
uniprot id: A0A0D4BVZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1618207:UM93 RS01900
gene id: 1618207:UM93_RS01900
uniprot id: A0A0D4BVZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1618207:UM93 RS14340
gene id: 1618207:UM93_RS14340
uniprot id: A0A0D4C109
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1618207:UM93 RS02880
gene id: 1618207:UM93_RS02880
uniprot id: A0A0D4BWM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1618207:UM93 RS07225
gene id: 1618207:UM93_RS07225
uniprot id: A0A0D4BYY2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1618207:UM93 RS10950
gene id: 1618207:UM93_RS10950
uniprot id: A0A0D4BZM4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1618207:UM93 RS02710
gene id: 1618207:UM93_RS02710
uniprot id: A0A0D4BWK5
names: Similarity
messages: Belongs to the AHA1 family.

1618207:UM93 RS04580
gene id: 1618207:UM93_RS04580
uniprot id: A0A0D4BWX4
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1618207:UM93 RS11900
gene id: 1618207:UM93_RS11900
uniprot id: A0A0D4C358
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS01700
gene id: 1618207:UM93_RS01700
uniprot id: A0A0D4BWT1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS16630
gene id: 1618207:UM93_RS16630
uniprot id: A0A0D4C2S8
names: Similarity
messages: Belongs to the TPP enzyme family.

1618207:UM93 RS07920
gene id: 1618207:UM93_RS07920
uniprot id: A0A0D4BYC2
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS11910
gene id: 1618207:UM93_RS11910
uniprot id: A0A0D4C0H4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08585
gene id: 1618207:UM93_RS08585
uniprot id: A0A0D4BZ03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1618207:UM93 RS03700
gene id: 1618207:UM93_RS03700
uniprot id: A0A0D4BWZ0
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1618207:UM93 RS04700
gene id: 1618207:UM93_RS04700
uniprot id: A0A0D4BXY7
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1618207:UM93 RS05035
gene id: 1618207:UM93_RS05035
uniprot id: A0A0D4BXL7
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1618207:UM93 RS06840
gene id: 1618207:UM93_RS06840
uniprot id: A0A0D4BYT8
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS04585
gene id: 1618207:UM93_RS04585
uniprot id: A0A0D4BXB7
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09620
gene id: 1618207:UM93_RS09620
uniprot id: A0A0D4BZG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1618207:UM93 RS10595
gene id: 1618207:UM93_RS10595
uniprot id: A0A0D4BZV6
names: Similarity
messages: Belongs to the catalase family.

1618207:UM93 RS05590
gene id: 1618207:UM93_RS05590
uniprot id: A0A0D4C2Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1618207:UM93 RS03825
gene id: 1618207:UM93_RS03825
uniprot id: A0A0D4BXK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1618207:UM93 RS07395
gene id: 1618207:UM93_RS07395
uniprot id: A0A0D4BYH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1618207:UM93 RS13970
gene id: 1618207:UM93_RS13970
uniprot id: A0A0D4C1N7
names: Similarity
messages: Belongs to the Dps family.

1618207:UM93 RS13705
gene id: 1618207:UM93_RS13705
uniprot id: A0A0D4C0S4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1618207:UM93 RS04720
gene id: 1618207:UM93_RS04720
uniprot id: A0A0D4C2H3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1618207:UM93 RS06480
gene id: 1618207:UM93_RS06480
uniprot id: A0A0D4BY47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1618207:UM93 RS12290
gene id: 1618207:UM93_RS12290
uniprot id: A0A0D4C0M2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1618207:UM93 RS16660
gene id: 1618207:UM93_RS16660
uniprot id: A0A0D4C2T2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1618207:UM93 RS00820
gene id: 1618207:UM93_RS00820
uniprot id: A0A0D4BVV1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1618207:UM93 RS13070
gene id: 1618207:UM93_RS13070
uniprot id: A0A0D4C1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1618207:UM93 RS15570
gene id: 1618207:UM93_RS15570
uniprot id: A0A0D4C1U5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1618207:UM93 RS04555
gene id: 1618207:UM93_RS04555
uniprot id: A0A0D4BXV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1618207:UM93 RS09845
gene id: 1618207:UM93_RS09845
uniprot id: A0A0D4C3S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1618207:UM93 RS00125
gene id: 1618207:UM93_RS00125
uniprot id: A0A0D4C2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS04820
gene id: 1618207:UM93_RS04820
uniprot id: A0A0D4BY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1618207:UM93 RS06350
gene id: 1618207:UM93_RS06350
uniprot id: A0A0D4BYM9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1618207:UM93 RS02825
gene id: 1618207:UM93_RS02825
uniprot id: A0A0D4BX72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1618207:UM93 RS08165
gene id: 1618207:UM93_RS08165
uniprot id: A0A0D4BYX0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1618207:UM93 RS14085
gene id: 1618207:UM93_RS14085
uniprot id: A0A0D4C1A5
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS08420
gene id: 1618207:UM93_RS08420
uniprot id: A0A0D4BYY3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1618207:UM93 RS01335
gene id: 1618207:UM93_RS01335
uniprot id: A0A0D4BWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1618207:UM93 RS14375
gene id: 1618207:UM93_RS14375
uniprot id: A0A0D4C1E6
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS13150
gene id: 1618207:UM93_RS13150
uniprot id: A0A0D4C0L1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS00510
gene id: 1618207:UM93_RS00510
uniprot id: A0A0D4BWB1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1618207:UM93 RS11635
gene id: 1618207:UM93_RS11635
uniprot id: A0A0D4C0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1618207:UM93 RS04710
gene id: 1618207:UM93_RS04710
uniprot id: A0A0D4BXD1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS13280
gene id: 1618207:UM93_RS13280
uniprot id: A0A0D4C1J7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1618207:UM93 RS00305
gene id: 1618207:UM93_RS00305
uniprot id: A0A0D4BVB5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1618207:UM93 RS00605
gene id: 1618207:UM93_RS00605
uniprot id: A0A0D4BVS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1618207:UM93 RS03570
gene id: 1618207:UM93_RS03570
uniprot id: A0A0D4C364
names: Similarity
messages: Belongs to the TrpC family.

1618207:UM93 RS08855
gene id: 1618207:UM93_RS08855
uniprot id: A0A0D4BZ71
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1618207:UM93 RS09505
gene id: 1618207:UM93_RS09505
uniprot id: A0A0D4BZD8
names: Similarity
messages: Belongs to the peptidase S58 family.

1618207:UM93 RS15280
gene id: 1618207:UM93_RS15280
uniprot id: A0A0D4C1H9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08670
gene id: 1618207:UM93_RS08670
uniprot id: A0A0D4C3Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1618207:UM93 RS13190
gene id: 1618207:UM93_RS13190
uniprot id: A0A0D4C3G6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1618207:UM93 RS11315
gene id: 1618207:UM93_RS11315
uniprot id: A0A0D4C055
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS16410
gene id: 1618207:UM93_RS16410
uniprot id: A0A0D4C249
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1618207:UM93 RS03245
gene id: 1618207:UM93_RS03245
uniprot id: A0A0D4BXD9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1618207:UM93 RS16295
gene id: 1618207:UM93_RS16295
uniprot id: A0A0D4C2R1
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1618207:UM93 RS06760
gene id: 1618207:UM93_RS06760
uniprot id: A0A0D4BY99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1618207:UM93 RS01260
gene id: 1618207:UM93_RS01260
uniprot id: A0A0D4BW31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1618207:UM93 RS05710
gene id: 1618207:UM93_RS05710
uniprot id: A0A0D4BXG4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1618207:UM93 RS03995
gene id: 1618207:UM93_RS03995
uniprot id: A0A0D4BX30
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1618207:UM93 RS00355
gene id: 1618207:UM93_RS00355
uniprot id: A0A0D4BW79
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1618207:UM93 RS03035
gene id: 1618207:UM93_RS03035
uniprot id: A0A0D4BWA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1618207:UM93 RS03940
gene id: 1618207:UM93_RS03940
uniprot id: A0A0D4BX20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1618207:UM93 RS11230
gene id: 1618207:UM93_RS11230
uniprot id: A0A0D4C043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

1618207:UM93 RS04860
gene id: 1618207:UM93_RS04860
uniprot id: A0A0D4BX48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1618207:UM93 RS10430
gene id: 1618207:UM93_RS10430
uniprot id: A0A0D4C0D2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1618207:UM93 RS02915
gene id: 1618207:UM93_RS02915
uniprot id: A0A0D4BX85
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1618207:UM93 RS07105
gene id: 1618207:UM93_RS07105
uniprot id: A0A0D4BYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1618207:UM93 RS16440
gene id: 1618207:UM93_RS16440
uniprot id: A0A0D4C4B3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1618207:UM93 RS06390
gene id: 1618207:UM93_RS06390
uniprot id: A0A0D4BXQ9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1618207:UM93 RS15380
gene id: 1618207:UM93_RS15380
uniprot id: A0A0D4C1S1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1618207:UM93 RS16040
gene id: 1618207:UM93_RS16040
uniprot id: A0A0D4C2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS16705
gene id: 1618207:UM93_RS16705
uniprot id: A0A0D4C202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS03980
gene id: 1618207:UM93_RS03980
uniprot id: A0A0D4BXL9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1618207:UM93 RS04805
gene id: 1618207:UM93_RS04805
uniprot id: A0A0D4BXH5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS01135
gene id: 1618207:UM93_RS01135
uniprot id: A0A0D4BW13
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1618207:UM93 RS15990
gene id: 1618207:UM93_RS15990
uniprot id: A0A0D4C2M2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS16155
gene id: 1618207:UM93_RS16155
uniprot id: A0A0D4C1S3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1618207:UM93 RS06235
gene id: 1618207:UM93_RS06235
uniprot id: A0A0D4BYN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1618207:UM93 RS16285
gene id: 1618207:UM93_RS16285
uniprot id: A0A0D4C278
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1618207:UM93 RS03535
gene id: 1618207:UM93_RS03535
uniprot id: A0A0D4BXG5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1618207:UM93 RS05540
gene id: 1618207:UM93_RS05540
uniprot id: A0A0D4BXT8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1618207:UM93 RS12980
gene id: 1618207:UM93_RS12980
uniprot id: A0A0D4C1G0
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1618207:UM93 RS04350
gene id: 1618207:UM93_RS04350
uniprot id: A0A0D4BWT9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1618207:UM93 RS16355
gene id: 1618207:UM93_RS16355
uniprot id: A0A0D4C240
names: Similarity
messages: Belongs to the peptidase C40 family.

1618207:UM93 RS14020
gene id: 1618207:UM93_RS14020
uniprot id: A0A0D4C195
names: Similarity
messages: Belongs to the UPF0098 family.

1618207:UM93 RS10380
gene id: 1618207:UM93_RS10380
uniprot id: A0A0D4BZR5
names: Similarity
messages: Belongs to the peptidase S58 family.

1618207:UM93 RS01390
gene id: 1618207:UM93_RS01390
uniprot id: A0A0D4BW50
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1618207:UM93 RS02500
gene id: 1618207:UM93_RS02500
uniprot id: A0A0D4BX27
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1618207:UM93 RS03135
gene id: 1618207:UM93_RS03135
uniprot id: A0A0D4C2S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1618207:UM93 RS15485
gene id: 1618207:UM93_RS15485
uniprot id: A0A0D4C2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1618207:UM93 RS11150
gene id: 1618207:UM93_RS11150
uniprot id: A0A0D4C0N9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1618207:UM93 RS03540
gene id: 1618207:UM93_RS03540
uniprot id: A0A0D4BWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1618207:UM93 RS01075
gene id: 1618207:UM93_RS01075
uniprot id: A0A0D4BWI5
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS10070
gene id: 1618207:UM93_RS10070
uniprot id: A0A0D4C044
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1618207:UM93 RS03815
gene id: 1618207:UM93_RS03815
uniprot id: A0A0D4BX06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1618207:UM93 RS15535
gene id: 1618207:UM93_RS15535
uniprot id: A0A0D4C1K9
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS07680
gene id: 1618207:UM93_RS07680
uniprot id: A0A0D4BZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS00430
gene id: 1618207:UM93_RS00430
uniprot id: A0A0D4BWA2
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1618207:UM93 RS10175
gene id: 1618207:UM93_RS10175
uniprot id: A0A0D4BZQ2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1618207:UM93 RS00515
gene id: 1618207:UM93_RS00515
uniprot id: A0A0D4BVE5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1618207:UM93 RS00325
gene id: 1618207:UM93_RS00325
uniprot id: A0A0D4BW76
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS04625
gene id: 1618207:UM93_RS04625
uniprot id: A0A0D4BXC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1618207:UM93 RS02350
gene id: 1618207:UM93_RS02350
uniprot id: A0A0D4BW28
names: Similarity
messages: Belongs to the PrpD family.

1618207:UM93 RS02180
gene id: 1618207:UM93_RS02180
uniprot id: A0A0D4BWG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1618207:UM93 RS07245
gene id: 1618207:UM93_RS07245
uniprot id: A0A0D4BYE8
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09710
gene id: 1618207:UM93_RS09710
uniprot id: A0A0D4BZG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1618207:UM93 RS08530
gene id: 1618207:UM93_RS08530
uniprot id: A0A0D4BZI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1618207:UM93 RS06205
gene id: 1618207:UM93_RS06205
uniprot id: A0A0D4C2K9
names: Similarity
messages: Belongs to the DprA/Smf family.

1618207:UM93 RS10930
gene id: 1618207:UM93_RS10930
uniprot id: A0A0D4C0K8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1618207:UM93 RS05440
gene id: 1618207:UM93_RS05440
uniprot id: A0A0D4BYA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1618207:UM93 RS10575
gene id: 1618207:UM93_RS10575
uniprot id: A0A0D4BZG9
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS07425
gene id: 1618207:UM93_RS07425
uniprot id: A0A0D4BYI7
names: Similarity
messages: Belongs to the DtxR/MntR family.

1618207:UM93 RS09610
gene id: 1618207:UM93_RS09610
uniprot id: A0A0D4BZ35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1618207:UM93 RS11280
gene id: 1618207:UM93_RS11280
uniprot id: A0A0D4C036
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1618207:UM93 RS09220
gene id: 1618207:UM93_RS09220
uniprot id: A0A0D4BYX6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1618207:UM93 RS09450
gene id: 1618207:UM93_RS09450
uniprot id: A0A0D4BZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1618207:UM93 RS02955
gene id: 1618207:UM93_RS02955
uniprot id: A0A0D4BWN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1618207:UM93 RS12035
gene id: 1618207:UM93_RS12035
uniprot id: A0A0D4C0I7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1618207:UM93 RS14935
gene id: 1618207:UM93_RS14935
uniprot id: A0A0D4C468
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS08225
gene id: 1618207:UM93_RS08225
uniprot id: A0A0D4C349
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1618207:UM93 RS08340
gene id: 1618207:UM93_RS08340
uniprot id: A0A0D4BYZ6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1618207:UM93 RS02190
gene id: 1618207:UM93_RS02190
uniprot id: A0A0D4C325
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1618207:UM93 RS06080
gene id: 1618207:UM93_RS06080
uniprot id: A0A0D4BXZ3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1618207:UM93 RS05735
gene id: 1618207:UM93_RS05735
uniprot id: A0A0D4BYE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1618207:UM93 RS00435
gene id: 1618207:UM93_RS00435
uniprot id: A0A0D4BVD5
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1618207:UM93 RS03960
gene id: 1618207:UM93_RS03960
uniprot id: A0A0D4BWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS07820
gene id: 1618207:UM93_RS07820
uniprot id: A0A0D4BZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1618207:UM93 RS09170
gene id: 1618207:UM93_RS09170
uniprot id: A0A0D4BZR9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS07500
gene id: 1618207:UM93_RS07500
uniprot id: A0A0D4BZ25
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1618207:UM93 RS10785
gene id: 1618207:UM93_RS10785
uniprot id: A0A0D4BZX4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1618207:UM93 RS09470
gene id: 1618207:UM93_RS09470
uniprot id: A0A0D4C005
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS09900
gene id: 1618207:UM93_RS09900
uniprot id: A0A0D4C020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS09375
gene id: 1618207:UM93_RS09375
uniprot id: A0A0D4BZ00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1618207:UM93 RS09475
gene id: 1618207:UM93_RS09475
uniprot id: A0A0D4BZ15
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1618207:UM93 RS03745
gene id: 1618207:UM93_RS03745
uniprot id: A0A0D4BWZ7
names: Similarity
messages: Belongs to the peptidase S33 family.

1618207:UM93 RS03905
gene id: 1618207:UM93_RS03905
uniprot id: A0A0D4BWM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1618207:UM93 RS07110
gene id: 1618207:UM93_RS07110
uniprot id: A0A0D4BYE5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1618207:UM93 RS14335
gene id: 1618207:UM93_RS14335
uniprot id: A0A0D4C1X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

1618207:UM93 RS06070
gene id: 1618207:UM93_RS06070
uniprot id: A0A0D4BYL3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1618207:UM93 RS15190
gene id: 1618207:UM93_RS15190
uniprot id: A0A0D4C2C6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1618207:UM93 RS12850
gene id: 1618207:UM93_RS12850
uniprot id: A0A0D4C0R0
names: Similarity
messages: Belongs to the universal stress protein A family.

1618207:UM93 RS09765
gene id: 1618207:UM93_RS09765
uniprot id: A0A0D4BZ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1618207:UM93 RS02020
gene id: 1618207:UM93_RS02020
uniprot id: A0A0D4C319
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1618207:UM93 RS06335
gene id: 1618207:UM93_RS06335
uniprot id: A0A0D4BXP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1618207:UM93 RS06320
gene id: 1618207:UM93_RS06320
uniprot id: A0A0D4BY36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1618207:UM93 RS16125
gene id: 1618207:UM93_RS16125
uniprot id: A0A0D4C1S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

1618207:UM93 RS09465
gene id: 1618207:UM93_RS09465
uniprot id: A0A0D4BZW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1618207:UM93 RS02550
gene id: 1618207:UM93_RS02550
uniprot id: A0A0D4BWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS15700
gene id: 1618207:UM93_RS15700
uniprot id: A0A0D4C2J0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1618207:UM93 RS02015
gene id: 1618207:UM93_RS02015
uniprot id: A0A0D4BWY8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1618207:UM93 RS09490
gene id: 1618207:UM93_RS09490
uniprot id: A0A0D4BZW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1618207:UM93 RS02465
gene id: 1618207:UM93_RS02465
uniprot id: A0A0D4BW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1618207:UM93 RS01020
gene id: 1618207:UM93_RS01020
uniprot id: A0A0D4BVY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1618207:UM93 RS07210
gene id: 1618207:UM93_RS07210
uniprot id: A0A0D4BYE3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS09255
gene id: 1618207:UM93_RS09255
uniprot id: A0A0D4BYY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1618207:UM93 RS11435
gene id: 1618207:UM93_RS11435
uniprot id: A0A0D4C057
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS15460
gene id: 1618207:UM93_RS15460
uniprot id: A0A0D4C1X5
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS00265
gene id: 1618207:UM93_RS00265
uniprot id: A0A0D4BW72
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1618207:UM93 RS02080
gene id: 1618207:UM93_RS02080
uniprot id: A0A0D4BWE6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS01730
gene id: 1618207:UM93_RS01730
uniprot id: A0A0D4BWT6
names: Similarity
messages: Belongs to the peptidase S33 family.

1618207:UM93 RS13510
gene id: 1618207:UM93_RS13510
uniprot id: A0A0D4C121
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1618207:UM93 RS12975
gene id: 1618207:UM93_RS12975
uniprot id: A0A0D4C1B6
names: Similarity
messages: Belongs to the citrate synthase family.

1618207:UM93 RS07035
gene id: 1618207:UM93_RS07035
uniprot id: A0A0D4BYB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1618207:UM93 RS00450
gene id: 1618207:UM93_RS00450
uniprot id: A0A0D4BVQ2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1618207:UM93 RS01585
gene id: 1618207:UM93_RS01585
uniprot id: A0A0D4C272
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1618207:UM93 RS02890
gene id: 1618207:UM93_RS02890
uniprot id: A0A0D4BX82
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1618207:UM93 RS07205
gene id: 1618207:UM93_RS07205
uniprot id: A0A0D4C324
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1618207:UM93 RS05955
gene id: 1618207:UM93_RS05955
uniprot id: A0A0D4BXX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1618207:UM93 RS16215
gene id: 1618207:UM93_RS16215
uniprot id: A0A0D4C2L9
names: Similarity
messages: Belongs to the FPG family.

1618207:UM93 RS13940
gene id: 1618207:UM93_RS13940
uniprot id: A0A0D4C1N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1618207:UM93 RS08775
gene id: 1618207:UM93_RS08775
uniprot id: A0A0D4BYT0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1618207:UM93 RS02900
gene id: 1618207:UM93_RS02900
uniprot id: A0A0D4BWM2
names: Similarity
messages: Belongs to the YggT family.

1618207:UM93 RS14110
gene id: 1618207:UM93_RS14110
uniprot id: A0A0D4C0X5
names: Similarity
messages: Belongs to the peptidase S51 family.

1618207:UM93 RS04475
gene id: 1618207:UM93_RS04475
uniprot id: A0A0D4BWV9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS12860
gene id: 1618207:UM93_RS12860
uniprot id: A0A0D4C1A2
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1618207:UM93 RS07455
gene id: 1618207:UM93_RS07455
uniprot id: A0A0D4BYJ1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1618207:UM93 RS07700
gene id: 1618207:UM93_RS07700
uniprot id: A0A0D4BZ58
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1618207:UM93 RS07230
gene id: 1618207:UM93_RS07230
uniprot id: A0A0D4BZ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1618207:UM93 RS04760
gene id: 1618207:UM93_RS04760
uniprot id: A0A0D4BY16
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS06200
gene id: 1618207:UM93_RS06200
uniprot id: A0A0D4BYK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1618207:UM93 RS06550
gene id: 1618207:UM93_RS06550
uniprot id: A0A0D4BY56
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS10545
gene id: 1618207:UM93_RS10545
uniprot id: A0A0D4BZU1
names: Similarity
messages: Belongs to the UPF0234 family.

1618207:UM93 RS09515
gene id: 1618207:UM93_RS09515
uniprot id: A0A0D4BZF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS03125
gene id: 1618207:UM93_RS03125
uniprot id: A0A0D4BXB4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1618207:UM93 RS07690
gene id: 1618207:UM93_RS07690
uniprot id: A0A0D4BYL2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1618207:UM93 RS07495
gene id: 1618207:UM93_RS07495
uniprot id: A0A0D4BYJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1618207:UM93 RS04910
gene id: 1618207:UM93_RS04910
uniprot id: A0A0D4BX59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1618207:UM93 RS04485
gene id: 1618207:UM93_RS04485
uniprot id: A0A0D4BXA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1618207:UM93 RS05870
gene id: 1618207:UM93_RS05870
uniprot id: A0A0D4BXY3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1618207:UM93 RS02820
gene id: 1618207:UM93_RS02820
uniprot id: A0A0D4BX58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1618207:UM93 RS14190
gene id: 1618207:UM93_RS14190
uniprot id: A0A0D4C184
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1618207:UM93 RS03640
gene id: 1618207:UM93_RS03640
uniprot id: A0A0D4BXG7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1618207:UM93 RS00615
gene id: 1618207:UM93_RS00615
uniprot id: A0A0D4BWC1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS07675
gene id: 1618207:UM93_RS07675
uniprot id: A0A0D4BZ51
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1618207:UM93 RS11350
gene id: 1618207:UM93_RS11350
uniprot id: A0A0D4C060
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1618207:UM93 RS08940
gene id: 1618207:UM93_RS08940
uniprot id: A0A0D4BZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1618207:UM93 RS09980
gene id: 1618207:UM93_RS09980
uniprot id: A0A0D4C080
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1618207:UM93 RS11100
gene id: 1618207:UM93_RS11100
uniprot id: A0A0D4C0I0
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09295
gene id: 1618207:UM93_RS09295
uniprot id: A0A0D4BZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1618207:UM93 RS06100
gene id: 1618207:UM93_RS06100
uniprot id: A0A0D4BYL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS14185
gene id: 1618207:UM93_RS14185
uniprot id: A0A0D4C0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1618207:UM93 RS04950
gene id: 1618207:UM93_RS04950
uniprot id: A0A0D4BXJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1618207:UM93 RS10640
gene id: 1618207:UM93_RS10640
uniprot id: A0A0D4BZH9
names: Similarity
messages: Belongs to the CdaR family.

1618207:UM93 RS09525
gene id: 1618207:UM93_RS09525
uniprot id: A0A0D4C014
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1618207:UM93 RS13735
gene id: 1618207:UM93_RS13735
uniprot id: A0A0D4C118
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1618207:UM93 RS02970
gene id: 1618207:UM93_RS02970
uniprot id: A0A0D4BX95
names: Similarity
messages: Belongs to the glutamine synthetase family.

1618207:UM93 RS16405
gene id: 1618207:UM93_RS16405
uniprot id: A0A0D4C1V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS00330
gene id: 1618207:UM93_RS00330
uniprot id: A0A0D4BW82
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1618207:UM93 RS16055
gene id: 1618207:UM93_RS16055
uniprot id: A0A0D4C1R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1618207:UM93 RS05815
gene id: 1618207:UM93_RS05815
uniprot id: A0A0D4BXH3
names: Similarity
messages: Belongs to the peptidase M1 family.

1618207:UM93 RS10390
gene id: 1618207:UM93_RS10390
uniprot id: A0A0D4BZS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1618207:UM93 RS06255
gene id: 1618207:UM93_RS06255
uniprot id: A0A0D4BYL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1618207:UM93 RS15820
gene id: 1618207:UM93_RS15820
uniprot id: A0A0D4C2K3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS02010
gene id: 1618207:UM93_RS02010
uniprot id: A0A0D4BWX6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1618207:UM93 RS01895
gene id: 1618207:UM93_RS01895
uniprot id: A0A0D4BWW8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1618207:UM93 RS02965
gene id: 1618207:UM93_RS02965
uniprot id: A0A0D4BX83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1618207:UM93 RS03020
gene id: 1618207:UM93_RS03020
uniprot id: A0A0D4BWP6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1618207:UM93 RS03945
gene id: 1618207:UM93_RS03945
uniprot id: A0A0D4BX23
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1618207:UM93 RS16380
gene id: 1618207:UM93_RS16380
uniprot id: A0A0D4C1V2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1618207:UM93 RS04560
gene id: 1618207:UM93_RS04560
uniprot id: A0A0D4C2G3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1618207:UM93 RS08780
gene id: 1618207:UM93_RS08780
uniprot id: A0A0D4BZ34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1618207:UM93 RS09455
gene id: 1618207:UM93_RS09455
uniprot id: A0A0D4BZD1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1618207:UM93 RS03445
gene id: 1618207:UM93_RS03445
uniprot id: A0A0D4BXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS08730
gene id: 1618207:UM93_RS08730
uniprot id: A0A0D4BZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS16270
gene id: 1618207:UM93_RS16270
uniprot id: A0A0D4C2Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1618207:UM93 RS05150
gene id: 1618207:UM93_RS05150
uniprot id: A0A0D4BXL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS11525
gene id: 1618207:UM93_RS11525
uniprot id: A0A0D4C0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1618207:UM93 RS05795
gene id: 1618207:UM93_RS05795
uniprot id: A0A0D4BXX2
names: Similarity
messages: Belongs to the FPG family.

1618207:UM93 RS10045
gene id: 1618207:UM93_RS10045
uniprot id: A0A0D4C087
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1618207:UM93 RS02340
gene id: 1618207:UM93_RS02340
uniprot id: A0A0D4BX11
names: Similarity
messages: Belongs to the citrate synthase family.

1618207:UM93 RS05135
gene id: 1618207:UM93_RS05135
uniprot id: A0A0D4BY65
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1618207:UM93 RS00705
gene id: 1618207:UM93_RS00705
uniprot id: A0A0D4BVT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1618207:UM93 RS16855
gene id: 1618207:UM93_RS16855
uniprot id: A0A0D4C221
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1618207:UM93 RS08985
gene id: 1618207:UM93_RS08985
uniprot id: A0A0D4BZ64
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS13710
gene id: 1618207:UM93_RS13710
uniprot id: A0A0D4C114
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS07345
gene id: 1618207:UM93_RS07345
uniprot id: A0A0D4BZ01
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS02455
gene id: 1618207:UM93_RS02455
uniprot id: A0A0D4BX33
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1618207:UM93 RS06400
gene id: 1618207:UM93_RS06400
uniprot id: A0A0D4BY53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1618207:UM93 RS10730
gene id: 1618207:UM93_RS10730
uniprot id: A0A0D4BZW7
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1618207:UM93 RS07200
gene id: 1618207:UM93_RS07200
uniprot id: A0A0D4BY08
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1618207:UM93 RS03335
gene id: 1618207:UM93_RS03335
uniprot id: A0A0D4BWU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1618207:UM93 RS04730
gene id: 1618207:UM93_RS04730
uniprot id: A0A0D4BXY0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1618207:UM93 RS02345
gene id: 1618207:UM93_RS02345
uniprot id: A0A0D4BX21
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1618207:UM93 RS01385
gene id: 1618207:UM93_RS01385
uniprot id: A0A0D4BW48
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1618207:UM93 RS05375
gene id: 1618207:UM93_RS05375
uniprot id: A0A0D4BYC6
names: Similarity
messages: Belongs to the YciI family.

1618207:UM93 RS09750
gene id: 1618207:UM93_RS09750
uniprot id: A0A0D4BZI2
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS11640
gene id: 1618207:UM93_RS11640
uniprot id: A0A0D4C0D3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1618207:UM93 RS12355
gene id: 1618207:UM93_RS12355
uniprot id: A0A0D4C0N3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1618207:UM93 RS16375
gene id: 1618207:UM93_RS16375
uniprot id: A0A0D4C2S1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1618207:UM93 RS09355
gene id: 1618207:UM93_RS09355
uniprot id: A0A0D4BZD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1618207:UM93 RS06345
gene id: 1618207:UM93_RS06345
uniprot id: A0A0D4BY42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1618207:UM93 RS12875
gene id: 1618207:UM93_RS12875
uniprot id: A0A0D4C0H3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1618207:UM93 RS09600
gene id: 1618207:UM93_RS09600
uniprot id: A0A0D4BZX7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1618207:UM93 RS16695
gene id: 1618207:UM93_RS16695
uniprot id: A0A0D4C2T5
names: Similarity
messages: Belongs to the peptidase S66 family.

1618207:UM93 RS14360
gene id: 1618207:UM93_RS14360
uniprot id: A0A0D4C1Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1618207:UM93 RS01970
gene id: 1618207:UM93_RS01970
uniprot id: A0A0D4BWD0
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09390
gene id: 1618207:UM93_RS09390
uniprot id: A0A0D4BZV1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1618207:UM93 RS14090
gene id: 1618207:UM93_RS14090
uniprot id: A0A0D4C1Q5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1618207:UM93 RS14140
gene id: 1618207:UM93_RS14140
uniprot id: A0A0D4C3N3
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS07980
gene id: 1618207:UM93_RS07980
uniprot id: A0A0D4BZA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1618207:UM93 RS10925
gene id: 1618207:UM93_RS10925
uniprot id: A0A0D4C0F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1618207:UM93 RS12160
gene id: 1618207:UM93_RS12160
uniprot id: A0A0D4C0K4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1618207:UM93 RS07535
gene id: 1618207:UM93_RS07535
uniprot id: A0A0D4BZ31
names: Similarity
messages: Belongs to the GSP E family.

1618207:UM93 RS09730
gene id: 1618207:UM93_RS09730
uniprot id: A0A0D4BZ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1618207:UM93 RS09410
gene id: 1618207:UM93_RS09410
uniprot id: A0A0D4BZC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS11755
gene id: 1618207:UM93_RS11755
uniprot id: A0A0D4C0V2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1618207:UM93 RS15160
gene id: 1618207:UM93_RS15160
uniprot id: A0A0D4C2C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS01300
gene id: 1618207:UM93_RS01300
uniprot id: A0A0D4C2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1618207:UM93 RS11460
gene id: 1618207:UM93_RS11460
uniprot id: A0A0D4BZU8
names: Similarity
messages: Belongs to the HIBADH-related family.

1618207:UM93 RS14355
gene id: 1618207:UM93_RS14355
uniprot id: A0A0D4C1T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1618207:UM93 RS10845
gene id: 1618207:UM93_RS10845
uniprot id: A0A0D4BZK9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1618207:UM93 RS07950
gene id: 1618207:UM93_RS07950
uniprot id: A0A0D4BYC7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1618207:UM93 RS07750
gene id: 1618207:UM93_RS07750
uniprot id: A0A0D4BY95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1618207:UM93 RS16830
gene id: 1618207:UM93_RS16830
uniprot id: A0A0D4C2V2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1618207:UM93 RS09215
gene id: 1618207:UM93_RS09215
uniprot id: A0A0D4BZX2
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1618207:UM93 RS09920
gene id: 1618207:UM93_RS09920
uniprot id: A0A0D4BZK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1618207:UM93 RS08435
gene id: 1618207:UM93_RS08435
uniprot id: A0A0D4BZ12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS01800
gene id: 1618207:UM93_RS01800
uniprot id: A0A0D4BWB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1618207:UM93 RS03840
gene id: 1618207:UM93_RS03840
uniprot id: A0A0D4BX08
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1618207:UM93 RS07325
gene id: 1618207:UM93_RS07325
uniprot id: A0A0D4BY27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS08190
gene id: 1618207:UM93_RS08190
uniprot id: A0A0D4BYX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS04075
gene id: 1618207:UM93_RS04075
uniprot id: A0A0D4BX41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS07135
gene id: 1618207:UM93_RS07135
uniprot id: A0A0D4BYF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1618207:UM93 RS13790
gene id: 1618207:UM93_RS13790
uniprot id: A0A0D4C123
names: Similarity
messages: Belongs to the peptidase S33 family.

1618207:UM93 RS08070
gene id: 1618207:UM93_RS08070
uniprot id: A0A0D4BZD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1618207:UM93 RS04445
gene id: 1618207:UM93_RS04445
uniprot id: A0A0D4BWV4
names: Similarity
messages: Belongs to the peptidase S9C family.

1618207:UM93 RS14845
gene id: 1618207:UM93_RS14845
uniprot id: A0A0D4C1L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1618207:UM93 RS11190
gene id: 1618207:UM93_RS11190
uniprot id: A0A0D4C026
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1618207:UM93 RS08790
gene id: 1618207:UM93_RS08790
uniprot id: A0A0D4BZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1618207:UM93 RS12730
gene id: 1618207:UM93_RS12730
uniprot id: A0A0D4C1D1
names: Similarity
messages: Belongs to the FPG family.

1618207:UM93 RS11095
gene id: 1618207:UM93_RS11095
uniprot id: A0A0D4C021
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1618207:UM93 RS12520
gene id: 1618207:UM93_RS12520
uniprot id: A0A0D4C0C2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1618207:UM93 RS04515
gene id: 1618207:UM93_RS04515
uniprot id: A0A0D4BXA6
names: Similarity
messages: Belongs to the asparagine synthetase family.

1618207:UM93 RS00795
gene id: 1618207:UM93_RS00795
uniprot id: A0A0D4BWE7
names: Similarity
messages: Belongs to the HIBADH-related family.

1618207:UM93 RS08555
gene id: 1618207:UM93_RS08555
uniprot id: A0A0D4BYZ8
names: Similarity
messages: Belongs to the peptidase M24B family.

1618207:UM93 RS11735
gene id: 1618207:UM93_RS11735
uniprot id: A0A0D4C0B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS05945
gene id: 1618207:UM93_RS05945
uniprot id: A0A0D4BYJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1618207:UM93 RS07865
gene id: 1618207:UM93_RS07865
uniprot id: A0A0D4BYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS03910
gene id: 1618207:UM93_RS03910
uniprot id: A0A0D4BX16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1618207:UM93 RS01825
gene id: 1618207:UM93_RS01825
uniprot id: A0A0D4BWA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1618207:UM93 RS05760
gene id: 1618207:UM93_RS05760
uniprot id: A0A0D4C2Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1618207:UM93 RS11565
gene id: 1618207:UM93_RS11565
uniprot id: A0A0D4C096
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1618207:UM93 RS11610
gene id: 1618207:UM93_RS11610
uniprot id: A0A0D4C0T5
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS11420
gene id: 1618207:UM93_RS11420
uniprot id: A0A0D4C0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS11880
gene id: 1618207:UM93_RS11880
uniprot id: A0A0D4C0W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS05640
gene id: 1618207:UM93_RS05640
uniprot id: A0A0D4BYD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1618207:UM93 RS04680
gene id: 1618207:UM93_RS04680
uniprot id: A0A0D4BXX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1618207:UM93 RS12130
gene id: 1618207:UM93_RS12130
uniprot id: A0A0D4C3Z6
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS08280
gene id: 1618207:UM93_RS08280
uniprot id: A0A0D4BYK9
names: Similarity
messages: Belongs to the DNA photolyase family.

1618207:UM93 RS10010
gene id: 1618207:UM93_RS10010
uniprot id: A0A0D4C034
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08690
gene id: 1618207:UM93_RS08690
uniprot id: A0A0D4BYR9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1618207:UM93 RS03600
gene id: 1618207:UM93_RS03600
uniprot id: A0A0D4BWX7
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1618207:UM93 RS00850
gene id: 1618207:UM93_RS00850
uniprot id: A0A0D4BWF6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1618207:UM93 RS06525
gene id: 1618207:UM93_RS06525
uniprot id: A0A0D4BYQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08255
gene id: 1618207:UM93_RS08255
uniprot id: A0A0D4C3M6
names: Similarity
messages: Belongs to the PspA/IM30 family.

1618207:UM93 RS16850
gene id: 1618207:UM93_RS16850
uniprot id: A0A0D4C2Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08705
gene id: 1618207:UM93_RS08705
uniprot id: A0A0D4BZK8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1618207:UM93 RS05000
gene id: 1618207:UM93_RS05000
uniprot id: A0A0D4BX73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1618207:UM93 RS07025
gene id: 1618207:UM93_RS07025
uniprot id: A0A0D4BXZ2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1618207:UM93 RS01185
gene id: 1618207:UM93_RS01185
uniprot id: A0A0D4BW16
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS01170
gene id: 1618207:UM93_RS01170
uniprot id: A0A0D4BVQ3
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS06795
gene id: 1618207:UM93_RS06795
uniprot id: A0A0D4BY88
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1618207:UM93 RS02070
gene id: 1618207:UM93_RS02070
uniprot id: A0A0D4BWD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1618207:UM93 RS09440
gene id: 1618207:UM93_RS09440
uniprot id: A0A0D4C001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1618207:UM93 RS01310
gene id: 1618207:UM93_RS01310
uniprot id: A0A0D4BWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1618207:UM93 RS07400
gene id: 1618207:UM93_RS07400
uniprot id: A0A0D4BYI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1618207:UM93 RS06405
gene id: 1618207:UM93_RS06405
uniprot id: A0A0D4BYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1618207:UM93 RS07295
gene id: 1618207:UM93_RS07295
uniprot id: A0A0D4BZ23
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1618207:UM93 RS15940
gene id: 1618207:UM93_RS15940
uniprot id: A0A0D4C2I4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1618207:UM93 RS06230
gene id: 1618207:UM93_RS06230
uniprot id: A0A0D4BYL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1618207:UM93 RS02275
gene id: 1618207:UM93_RS02275
uniprot id: A0A0D4BX13
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1618207:UM93 RS09960
gene id: 1618207:UM93_RS09960
uniprot id: A0A0D4BZK5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1618207:UM93 RS07340
gene id: 1618207:UM93_RS07340
uniprot id: A0A0D4BYH3
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS16200
gene id: 1618207:UM93_RS16200
uniprot id: A0A0D4C3N8
names: Similarity
messages: Belongs to the asp23 family.

1618207:UM93 RS03160
gene id: 1618207:UM93_RS03160
uniprot id: A0A0D4BWS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS02680
gene id: 1618207:UM93_RS02680
uniprot id: A0A0D4BX57
names: Similarity
messages: Belongs to the peptidase S33 family.

1618207:UM93 RS00260
gene id: 1618207:UM93_RS00260
uniprot id: A0A0D4BW67
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1618207:UM93 RS01975
gene id: 1618207:UM93_RS01975
uniprot id: A0A0D4BWX1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1618207:UM93 RS04755
gene id: 1618207:UM93_RS04755
uniprot id: A0A0D4BY07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1618207:UM93 RS12205
gene id: 1618207:UM93_RS12205
uniprot id: A0A0D4C162
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS05115
gene id: 1618207:UM93_RS05115
uniprot id: A0A0D4BXL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS12260
gene id: 1618207:UM93_RS12260
uniprot id: A0A0D4C0L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS03935
gene id: 1618207:UM93_RS03935
uniprot id: A0A0D4BWM8
names: Similarity
messages: Belongs to the GPI family.

1618207:UM93 RS09235
gene id: 1618207:UM93_RS09235
uniprot id: A0A0D4BZB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1618207:UM93 RS00720
gene id: 1618207:UM93_RS00720
uniprot id: A0A0D4BVH1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1618207:UM93 RS09685
gene id: 1618207:UM93_RS09685
uniprot id: A0A0D4BZH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1618207:UM93 RS12645
gene id: 1618207:UM93_RS12645
uniprot id: A0A0D4C0E2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1618207:UM93 RS00645
gene id: 1618207:UM93_RS00645
uniprot id: A0A0D4BWC3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1618207:UM93 RS09380
gene id: 1618207:UM93_RS09380
uniprot id: A0A0D4BZC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1618207:UM93 RS15955
gene id: 1618207:UM93_RS15955
uniprot id: A0A0D4C2L8
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1618207:UM93 RS00545
gene id: 1618207:UM93_RS00545
uniprot id: A0A0D4BWB4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1618207:UM93 RS15840
gene id: 1618207:UM93_RS15840
uniprot id: A0A0D4C228
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1618207:UM93 RS04890
gene id: 1618207:UM93_RS04890
uniprot id: A0A0D4BXH6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1618207:UM93 RS02845
gene id: 1618207:UM93_RS02845
uniprot id: A0A0D4BWL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1618207:UM93 RS15475
gene id: 1618207:UM93_RS15475
uniprot id: A0A0D4C3Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1618207:UM93 RS00395
gene id: 1618207:UM93_RS00395
uniprot id: A0A0D4BW95
names: Similarity
messages: Belongs to the peptidase S8 family.

1618207:UM93 RS06245
gene id: 1618207:UM93_RS06245
uniprot id: A0A0D4BY09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1618207:UM93 RS14755
gene id: 1618207:UM93_RS14755
uniprot id: A0A0D4C465
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS11605
gene id: 1618207:UM93_RS11605
uniprot id: A0A0D4C0C9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1618207:UM93 RS00475
gene id: 1618207:UM93_RS00475
uniprot id: A0A0D4BVE0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS03090
gene id: 1618207:UM93_RS03090
uniprot id: A0A0D4BWQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1618207:UM93 RS04545
gene id: 1618207:UM93_RS04545
uniprot id: A0A0D4BXB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1618207:UM93 RS08715
gene id: 1618207:UM93_RS08715
uniprot id: A0A0D4BZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1618207:UM93 RS11995
gene id: 1618207:UM93_RS11995
uniprot id: A0A0D4C0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1618207:UM93 RS03550
gene id: 1618207:UM93_RS03550
uniprot id: A0A0D4BWX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1618207:UM93 RS03085
gene id: 1618207:UM93_RS03085
uniprot id: A0A0D4BWC4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1618207:UM93 RS18050
gene id: 1618207:UM93_RS18050
uniprot id: A0A0D4C1F9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1618207:UM93 RS14300
gene id: 1618207:UM93_RS14300
uniprot id: A0A0D4C103
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1618207:UM93 RS01720
gene id: 1618207:UM93_RS01720
uniprot id: A0A0D4BW92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1618207:UM93 RS13555
gene id: 1618207:UM93_RS13555
uniprot id: A0A0D4C0Q6
names: Similarity
messages: Belongs to the ParB family.

1618207:UM93 RS10630
gene id: 1618207:UM93_RS10630
uniprot id: A0A0D4C0B0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1618207:UM93 RS15790
gene id: 1618207:UM93_RS15790
uniprot id: A0A0D4C2J8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1618207:UM93 RS16310
gene id: 1618207:UM93_RS16310
uniprot id: A0A0D4C281
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1618207:UM93 RS15560
gene id: 1618207:UM93_RS15560
uniprot id: A0A0D4C2G9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1618207:UM93 RS11330
gene id: 1618207:UM93_RS11330
uniprot id: A0A0D4C0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS02030
gene id: 1618207:UM93_RS02030
uniprot id: A0A0D4BW02
names: Similarity
messages: Belongs to the peptidase M1 family.

1618207:UM93 RS04750
gene id: 1618207:UM93_RS04750
uniprot id: A0A0D4BXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1618207:UM93 RS11520
gene id: 1618207:UM93_RS11520
uniprot id: A0A0D4C0N7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1618207:UM93 RS06465
gene id: 1618207:UM93_RS06465
uniprot id: A0A0D4BYP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1618207:UM93 RS00680
gene id: 1618207:UM93_RS00680
uniprot id: A0A0D4BWD2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1618207:UM93 RS15055
gene id: 1618207:UM93_RS15055
uniprot id: A0A0D4C1N9
names: Similarity
messages: Belongs to the universal stress protein A family.

1618207:UM93 RS08795
gene id: 1618207:UM93_RS08795
uniprot id: A0A0D4BZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1618207:UM93 RS03105
gene id: 1618207:UM93_RS03105
uniprot id: A0A0D4BXC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1618207:UM93 RS09680
gene id: 1618207:UM93_RS09680
uniprot id: A0A0D4BZF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1618207:UM93 RS04670
gene id: 1618207:UM93_RS04670
uniprot id: A0A0D4BXC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08520
gene id: 1618207:UM93_RS08520
uniprot id: A0A0D4BZ22
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1618207:UM93 RS02780
gene id: 1618207:UM93_RS02780
uniprot id: A0A0D4C348
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1618207:UM93 RS04040
gene id: 1618207:UM93_RS04040
uniprot id: A0A0D4BX36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1618207:UM93 RS02810
gene id: 1618207:UM93_RS02810
uniprot id: A0A0D4C2K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1618207:UM93 RS04880
gene id: 1618207:UM93_RS04880
uniprot id: A0A0D4BY44
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1618207:UM93 RS04705
gene id: 1618207:UM93_RS04705
uniprot id: A0A0D4BWY9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1618207:UM93 RS00500
gene id: 1618207:UM93_RS00500
uniprot id: A0A0D4BW96
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS02910
gene id: 1618207:UM93_RS02910
uniprot id: A0A0D4BX74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1618207:UM93 RS06190
gene id: 1618207:UM93_RS06190
uniprot id: A0A0D4BY02
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1618207:UM93 RS04450
gene id: 1618207:UM93_RS04450
uniprot id: A0A0D4BX99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1618207:UM93 RS11205
gene id: 1618207:UM93_RS11205
uniprot id: A0A0D4C0Q0
names: Similarity
messages: Belongs to the peptidase C1 family.

1618207:UM93 RS12445
gene id: 1618207:UM93_RS12445
uniprot id: A0A0D4C196
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1618207:UM93 RS05495
gene id: 1618207:UM93_RS05495
uniprot id: A0A0D4BXE1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1618207:UM93 RS09785
gene id: 1618207:UM93_RS09785
uniprot id: A0A0D4C052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS01295
gene id: 1618207:UM93_RS01295
uniprot id: A0A0D4BWM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1618207:UM93 RS07870
gene id: 1618207:UM93_RS07870
uniprot id: A0A0D4BYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS06210
gene id: 1618207:UM93_RS06210
uniprot id: A0A0D4BYN4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1618207:UM93 RS09495
gene id: 1618207:UM93_RS09495
uniprot id: A0A0D4C009
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1618207:UM93 RS06700
gene id: 1618207:UM93_RS06700
uniprot id: A0A0D4BYS3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1618207:UM93 RS09775
gene id: 1618207:UM93_RS09775
uniprot id: A0A0D4BZI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1618207:UM93 RS03000
gene id: 1618207:UM93_RS03000
uniprot id: A0A0D4BXA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS01705
gene id: 1618207:UM93_RS01705
uniprot id: A0A0D4BWU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1618207:UM93 RS04460
gene id: 1618207:UM93_RS04460
uniprot id: A0A0D4BXU2
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1618207:UM93 RS03835
gene id: 1618207:UM93_RS03835
uniprot id: A0A0D4C2T7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1618207:UM93 RS02885
gene id: 1618207:UM93_RS02885
uniprot id: A0A0D4BX69
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1618207:UM93 RS05455
gene id: 1618207:UM93_RS05455
uniprot id: A0A0D4BXD8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1618207:UM93 RS14940
gene id: 1618207:UM93_RS14940
uniprot id: A0A0D4C265
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1618207:UM93 RS07490
gene id: 1618207:UM93_RS07490
uniprot id: A0A0D4BYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1618207:UM93 RS12820
gene id: 1618207:UM93_RS12820
uniprot id: A0A0D4C198
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1618207:UM93 RS15670
gene id: 1618207:UM93_RS15670
uniprot id: A0A0D4C1W0
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS07145
gene id: 1618207:UM93_RS07145
uniprot id: A0A0D4BZ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1618207:UM93 RS00710
gene id: 1618207:UM93_RS00710
uniprot id: A0A0D4BWD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1618207:UM93 RS10165
gene id: 1618207:UM93_RS10165
uniprot id: A0A0D4BZC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS01510
gene id: 1618207:UM93_RS01510
uniprot id: A0A0D4BWS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1618207:UM93 RS02415
gene id: 1618207:UM93_RS02415
uniprot id: A0A0D4BW38
names: Subcellular Location Annotation
messages: Cytoplasm

1618207:UM93 RS12655
gene id: 1618207:UM93_RS12655
uniprot id: A0A0D4C0S0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS06425
gene id: 1618207:UM93_RS06425
uniprot id: A0A0D4BY60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1618207:UM93 RS07890
gene id: 1618207:UM93_RS07890
uniprot id: A0A0D4BYB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08205
gene id: 1618207:UM93_RS08205
uniprot id: A0A0D4BZI0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1618207:UM93 RS15335
gene id: 1618207:UM93_RS15335
uniprot id: A0A0D4C2B1
names: Similarity
messages: Belongs to the thioesterase family.

1618207:UM93 RS09300
gene id: 1618207:UM93_RS09300
uniprot id: A0A0D4BZT8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1618207:UM93 RS14380
gene id: 1618207:UM93_RS14380
uniprot id: A0A0D4C1U4
names: Similarity
messages: Belongs to the PhoU family.

1618207:UM93 RS03525
gene id: 1618207:UM93_RS03525
uniprot id: A0A0D4BWW7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1618207:UM93 RS07065
gene id: 1618207:UM93_RS07065
uniprot id: A0A0D4BXZ5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS09335
gene id: 1618207:UM93_RS09335
uniprot id: A0A0D4BZU2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1618207:UM93 RS07390
gene id: 1618207:UM93_RS07390
uniprot id: A0A0D4BY38
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09755
gene id: 1618207:UM93_RS09755
uniprot id: A0A0D4BZZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS08385
gene id: 1618207:UM93_RS08385
uniprot id: A0A0D4BYX8
names: Similarity
messages: Belongs to the peptidase S33 family.

1618207:UM93 RS00540
gene id: 1618207:UM93_RS00540
uniprot id: A0A0D4BWA0
names: Similarity
messages: Belongs to the FemABX family.

1618207:UM93 RS10670
gene id: 1618207:UM93_RS10670
uniprot id: A0A0D4C0G8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1618207:UM93 RS09955
gene id: 1618207:UM93_RS09955
uniprot id: A0A0D4BZ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1618207:UM93 RS04845
gene id: 1618207:UM93_RS04845
uniprot id: A0A0D4BXI0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1618207:UM93 RS04640
gene id: 1618207:UM93_RS04640
uniprot id: A0A0D4BXY1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1618207:UM93 RS06655
gene id: 1618207:UM93_RS06655
uniprot id: A0A0D4BYS0
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09500
gene id: 1618207:UM93_RS09500
uniprot id: A0A0D4BZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1618207:UM93 RS11805
gene id: 1618207:UM93_RS11805
uniprot id: A0A0D4C0C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1618207:UM93 RS10760
gene id: 1618207:UM93_RS10760
uniprot id: A0A0D4BZX0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1618207:UM93 RS14095
gene id: 1618207:UM93_RS14095
uniprot id: A0A0D4C1U2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1618207:UM93 RS11970
gene id: 1618207:UM93_RS11970
uniprot id: A0A0D4C0H9
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS04945
gene id: 1618207:UM93_RS04945
uniprot id: A0A0D4BXI6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1618207:UM93 RS11305
gene id: 1618207:UM93_RS11305
uniprot id: A0A0D4BZS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1618207:UM93 RS00555
gene id: 1618207:UM93_RS00555
uniprot id: A0A0D4BVS3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1618207:UM93 RS07235
gene id: 1618207:UM93_RS07235
uniprot id: A0A0D4BY13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1618207:UM93 RS04470
gene id: 1618207:UM93_RS04470
uniprot id: A0A0D4BXV6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS10420
gene id: 1618207:UM93_RS10420
uniprot id: A0A0D4BZT4
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS04300
gene id: 1618207:UM93_RS04300
uniprot id: A0A0D4BXR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1618207:UM93 RS01120
gene id: 1618207:UM93_RS01120
uniprot id: A0A0D4BWK6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1618207:UM93 RS04225
gene id: 1618207:UM93_RS04225
uniprot id: A0A0D4BXR8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

1618207:UM93 RS09630
gene id: 1618207:UM93_RS09630
uniprot id: A0A0D4BZY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1618207:UM93 RS07320
gene id: 1618207:UM93_RS07320
uniprot id: A0A0D4BZ27
names: Similarity
messages: Belongs to the Fur family.

1618207:UM93 RS03140
gene id: 1618207:UM93_RS03140
uniprot id: A0A0D4BWD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1618207:UM93 RS01965
gene id: 1618207:UM93_RS01965
uniprot id: A0A0D4BWC5
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS05980
gene id: 1618207:UM93_RS05980
uniprot id: A0A0D4BYK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1618207:UM93 RS04530
gene id: 1618207:UM93_RS04530
uniprot id: A0A0D4BXW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1618207:UM93 RS16805
gene id: 1618207:UM93_RS16805
uniprot id: A0A0D4C216
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS06360
gene id: 1618207:UM93_RS06360
uniprot id: A0A0D4BXQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1618207:UM93 RS02685
gene id: 1618207:UM93_RS02685
uniprot id: A0A0D4BW63
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1618207:UM93 RS16490
gene id: 1618207:UM93_RS16490
uniprot id: A0A0D4C2A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1618207:UM93 RS16570
gene id: 1618207:UM93_RS16570
uniprot id: A0A0D4C2R8
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS06250
gene id: 1618207:UM93_RS06250
uniprot id: A0A0D4BY28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1618207:UM93 RS16005
gene id: 1618207:UM93_RS16005
uniprot id: A0A0D4C1Z9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1618207:UM93 RS01520
gene id: 1618207:UM93_RS01520
uniprot id: A0A0D4BW70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1618207:UM93 RS06290
gene id: 1618207:UM93_RS06290
uniprot id: A0A0D4BYL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1618207:UM93 RS16280
gene id: 1618207:UM93_RS16280
uniprot id: A0A0D4C230
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1618207:UM93 RS14260
gene id: 1618207:UM93_RS14260
uniprot id: A0A0D4C0Z8
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

1618207:UM93 RS14910
gene id: 1618207:UM93_RS14910
uniprot id: A0A0D4C260
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1618207:UM93 RS15910
gene id: 1618207:UM93_RS15910
uniprot id: A0A0D4C1Q0
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1618207:UM93 RS09345
gene id: 1618207:UM93_RS09345
uniprot id: A0A0D4BYZ5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1618207:UM93 RS00400
gene id: 1618207:UM93_RS00400
uniprot id: A0A0D4BVD0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1618207:UM93 RS08375
gene id: 1618207:UM93_RS08375
uniprot id: A0A0D4BZK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS09590
gene id: 1618207:UM93_RS09590
uniprot id: A0A0D4BZG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1618207:UM93 RS05800
gene id: 1618207:UM93_RS05800
uniprot id: A0A0D4BYF3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1618207:UM93 RS12755
gene id: 1618207:UM93_RS12755
uniprot id: A0A0D4C187
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1618207:UM93 RS04005
gene id: 1618207:UM93_RS04005
uniprot id: A0A0D4BXM5
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS11345
gene id: 1618207:UM93_RS11345
uniprot id: A0A0D4C046
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1618207:UM93 RS05700
gene id: 1618207:UM93_RS05700
uniprot id: A0A0D4BYH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1618207:UM93 RS12840
gene id: 1618207:UM93_RS12840
uniprot id: A0A0D4C0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1618207:UM93 RS07945
gene id: 1618207:UM93_RS07945
uniprot id: A0A0D4BZB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1618207:UM93 RS08890
gene id: 1618207:UM93_RS08890
uniprot id: A0A0D4BZ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1618207:UM93 RS06090
gene id: 1618207:UM93_RS06090
uniprot id: A0A0D4BYI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1618207:UM93 RS07985
gene id: 1618207:UM93_RS07985
uniprot id: A0A0D4BZC3
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS04365
gene id: 1618207:UM93_RS04365
uniprot id: A0A0D4BX81
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1618207:UM93 RS13920
gene id: 1618207:UM93_RS13920
uniprot id: A0A0D4C1R6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1618207:UM93 RS01580
gene id: 1618207:UM93_RS01580
uniprot id: A0A0D4BW78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1618207:UM93 RS04895
gene id: 1618207:UM93_RS04895
uniprot id: A0A0D4BXI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS14890
gene id: 1618207:UM93_RS14890
uniprot id: A0A0D4C1I1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1618207:UM93 RS05490
gene id: 1618207:UM93_RS05490
uniprot id: A0A0D4BYE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1618207:UM93 RS06185
gene id: 1618207:UM93_RS06185
uniprot id: A0A0D4BXM4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1618207:UM93 RS13535
gene id: 1618207:UM93_RS13535
uniprot id: A0A0D4C126
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1618207:UM93 RS01920
gene id: 1618207:UM93_RS01920
uniprot id: A0A0D4BWW1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS13030
gene id: 1618207:UM93_RS13030
uniprot id: A0A0D4C0W3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1618207:UM93 RS08055
gene id: 1618207:UM93_RS08055
uniprot id: A0A0D4BZB1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1618207:UM93 RS03950
gene id: 1618207:UM93_RS03950
uniprot id: A0A0D4BXL4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1618207:UM93 RS10915
gene id: 1618207:UM93_RS10915
uniprot id: A0A0D4BZZ0
names: Similarity
messages: Belongs to the peptidase S1B family.

1618207:UM93 RS03500
gene id: 1618207:UM93_RS03500
uniprot id: A0A0D4BXG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1618207:UM93 RS03485
gene id: 1618207:UM93_RS03485
uniprot id: A0A0D4BWW0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1618207:UM93 RS08105
gene id: 1618207:UM93_RS08105
uniprot id: A0A0D4C342
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1618207:UM93 RS12970
gene id: 1618207:UM93_RS12970
uniprot id: A0A0D4C0V7
names: Similarity
messages: Belongs to the citrate synthase family.

1618207:UM93 RS05240
gene id: 1618207:UM93_RS05240
uniprot id: A0A0D4BYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1618207:UM93 RS05650
gene id: 1618207:UM93_RS05650
uniprot id: A0A0D4BXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1618207:UM93 RS02855
gene id: 1618207:UM93_RS02855
uniprot id: A0A0D4BX76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1618207:UM93 RS09325
gene id: 1618207:UM93_RS09325
uniprot id: A0A0D4BZB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS05660
gene id: 1618207:UM93_RS05660
uniprot id: A0A0D4BXV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1618207:UM93 RS11165
gene id: 1618207:UM93_RS11165
uniprot id: A0A0D4C022
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1618207:UM93 RS01285
gene id: 1618207:UM93_RS01285
uniprot id: A0A0D4BW35
names: Similarity
messages: Belongs to the AHA1 family.

1618207:UM93 RS14950
gene id: 1618207:UM93_RS14950
uniprot id: A0A0D4C3D5
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS03555
gene id: 1618207:UM93_RS03555
uniprot id: A0A0D4BXF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1618207:UM93 RS13945
gene id: 1618207:UM93_RS13945
uniprot id: A0A0D4C1S2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1618207:UM93 RS09340
gene id: 1618207:UM93_RS09340
uniprot id: A0A0D4BZY8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1618207:UM93 RS13645
gene id: 1618207:UM93_RS13645
uniprot id: A0A0D4C1J8
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS07405
gene id: 1618207:UM93_RS07405
uniprot id: A0A0D4BZ10
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1618207:UM93 RS07115
gene id: 1618207:UM93_RS07115
uniprot id: A0A0D4BYW6
names: Subcellular Location Annotation
messages: Cytoplasm

1618207:UM93 RS07000
gene id: 1618207:UM93_RS07000
uniprot id: A0A0D4BYC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1618207:UM93 RS08270
gene id: 1618207:UM93_RS08270
uniprot id: A0A0D4BZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1618207:UM93 RS13865
gene id: 1618207:UM93_RS13865
uniprot id: A0A0D4C133
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS06240
gene id: 1618207:UM93_RS06240
uniprot id: A0A0D4BXN2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1618207:UM93 RS10090
gene id: 1618207:UM93_RS10090
uniprot id: A0A0D4BZN8
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

1618207:UM93 RS06620
gene id: 1618207:UM93_RS06620
uniprot id: A0A0D4BYR5
names: Similarity
messages: Belongs to the DSD1 family.

1618207:UM93 RS10580
gene id: 1618207:UM93_RS10580
uniprot id: A0A0D4BZU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS07525
gene id: 1618207:UM93_RS07525
uniprot id: A0A0D4BYI8
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS00090
gene id: 1618207:UM93_RS00090
uniprot id: A0A0D4BW46
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS03260
gene id: 1618207:UM93_RS03260
uniprot id: A0A0D4BWE8
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS08820
gene id: 1618207:UM93_RS08820
uniprot id: A0A0D4BZM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS11585
gene id: 1618207:UM93_RS11585
uniprot id: A0A0D4C0X1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09870
gene id: 1618207:UM93_RS09870
uniprot id: A0A0D4BZK2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1618207:UM93 RS05450
gene id: 1618207:UM93_RS05450
uniprot id: A0A0D4BYD6
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1618207:UM93 RS04790
gene id: 1618207:UM93_RS04790
uniprot id: A0A0D4BX37
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1618207:UM93 RS04525
gene id: 1618207:UM93_RS04525
uniprot id: A0A0D4BXV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1618207:UM93 RS03775
gene id: 1618207:UM93_RS03775
uniprot id: A0A0D4BX00
names: Similarity
messages: Belongs to the AHA1 family.

1618207:UM93 RS08600
gene id: 1618207:UM93_RS08600
uniprot id: A0A0D4BZN7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1618207:UM93 RS11885
gene id: 1618207:UM93_RS11885
uniprot id: A0A0D4C122
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS10775
gene id: 1618207:UM93_RS10775
uniprot id: A0A0D4C0I3
names: Similarity
messages: Belongs to the isochorismate synthase family.

1618207:UM93 RS01485
gene id: 1618207:UM93_RS01485
uniprot id: A0A0D4BVU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1618207:UM93 RS03080
gene id: 1618207:UM93_RS03080
uniprot id: A0A0D4BXB5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1618207:UM93 RS10155
gene id: 1618207:UM93_RS10155
uniprot id: A0A0D4C059
names: Similarity
messages: Belongs to the UPF0336 family.

1618207:UM93 RS07140
gene id: 1618207:UM93_RS07140
uniprot id: A0A0D4BYX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1618207:UM93 RS09135
gene id: 1618207:UM93_RS09135
uniprot id: A0A0D4BZW3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1618207:UM93 RS15960
gene id: 1618207:UM93_RS15960
uniprot id: A0A0D4C4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1618207:UM93 RS14365
gene id: 1618207:UM93_RS14365
uniprot id: A0A0D4C113
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1618207:UM93 RS13695
gene id: 1618207:UM93_RS13695
uniprot id: A0A0D4C1K3
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS14920
gene id: 1618207:UM93_RS14920
uniprot id: A0A0D4C1I6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1618207:UM93 RS09910
gene id: 1618207:UM93_RS09910
uniprot id: A0A0D4C071
names: Subcellular Location Annotation
messages: cytosol

1618207:UM93 RS15565
gene id: 1618207:UM93_RS15565
uniprot id: A0A0D4C1L3
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1618207:UM93 RS06935
gene id: 1618207:UM93_RS06935
uniprot id: A0A0D4BXY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1618207:UM93 RS08000
gene id: 1618207:UM93_RS08000
uniprot id: A0A0D4BYS1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1618207:UM93 RS08735
gene id: 1618207:UM93_RS08735
uniprot id: A0A0D4BZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS13685
gene id: 1618207:UM93_RS13685
uniprot id: A0A0D4C146
names: Similarity
messages: Belongs to the peptidase M18 family.

1618207:UM93 RS01750
gene id: 1618207:UM93_RS01750
uniprot id: A0A0D4BW97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS03520
gene id: 1618207:UM93_RS03520
uniprot id: A0A0D4BWW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1618207:UM93 RS03670
gene id: 1618207:UM93_RS03670
uniprot id: A0A0D4BXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1618207:UM93 RS13495
gene id: 1618207:UM93_RS13495
uniprot id: A0A0D4C3H6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1618207:UM93 RS03415
gene id: 1618207:UM93_RS03415
uniprot id: A0A0D4BXF1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1618207:UM93 RS08860
gene id: 1618207:UM93_RS08860
uniprot id: A0A0D4BZN1
names: Similarity
messages: Belongs to the pirin family.

1618207:UM93 RS13900
gene id: 1618207:UM93_RS13900
uniprot id: A0A0D4C138
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1618207:UM93 RS02060
gene id: 1618207:UM93_RS02060
uniprot id: A0A0D4BWZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1618207:UM93 RS10745
gene id: 1618207:UM93_RS10745
uniprot id: A0A0D4C0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1618207:UM93 RS11700
gene id: 1618207:UM93_RS11700
uniprot id: A0A0D4C0B2
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS03730
gene id: 1618207:UM93_RS03730
uniprot id: A0A0D4BWK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1618207:UM93 RS11840
gene id: 1618207:UM93_RS11840
uniprot id: A0A0D4C0D0
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS16385
gene id: 1618207:UM93_RS16385
uniprot id: A0A0D4C244
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1618207:UM93 RS01555
gene id: 1618207:UM93_RS01555
uniprot id: A0A0D4BW75
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1618207:UM93 RS13455
gene id: 1618207:UM93_RS13455
uniprot id: A0A0D4C1H2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1618207:UM93 RS15620
gene id: 1618207:UM93_RS15620
uniprot id: A0A0D4C2E4
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS08100
gene id: 1618207:UM93_RS08100
uniprot id: A0A0D4BYE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1618207:UM93 RS04490
gene id: 1618207:UM93_RS04490
uniprot id: A0A0D4BXU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1618207:UM93 RS01525
gene id: 1618207:UM93_RS01525
uniprot id: A0A0D4BW69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1618207:UM93 RS11075
gene id: 1618207:UM93_RS11075
uniprot id: A0A0D4C0H5
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS14165
gene id: 1618207:UM93_RS14165
uniprot id: A0A0D4C1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1618207:UM93 RS06530
gene id: 1618207:UM93_RS06530
uniprot id: A0A0D4BYT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1618207:UM93 RS04325
gene id: 1618207:UM93_RS04325
uniprot id: A0A0D4BX77
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1618207:UM93 RS02715
gene id: 1618207:UM93_RS02715
uniprot id: A0A0D4BX49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1618207:UM93 RS03040
gene id: 1618207:UM93_RS03040
uniprot id: A0A0D4BWP8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1618207:UM93 RS12050
gene id: 1618207:UM93_RS12050
uniprot id: A0A0D4C074
names: Similarity
messages: Belongs to the universal stress protein A family.

1618207:UM93 RS10830
gene id: 1618207:UM93_RS10830
uniprot id: A0A0D4C0D9
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS09715
gene id: 1618207:UM93_RS09715
uniprot id: A0A0D4BZH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1618207:UM93 RS14700
gene id: 1618207:UM93_RS14700
uniprot id: A0A0D4C1F7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1618207:UM93 RS09265
gene id: 1618207:UM93_RS09265
uniprot id: A0A0D4BZC1
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1618207:UM93 RS08515
gene id: 1618207:UM93_RS08515
uniprot id: A0A0D4BYZ3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1618207:UM93 RS11055
gene id: 1618207:UM93_RS11055
uniprot id: A0A0D4BZN9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS08695
gene id: 1618207:UM93_RS08695
uniprot id: A0A0D4BZ19
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1618207:UM93 RS02120
gene id: 1618207:UM93_RS02120
uniprot id: A0A0D4BX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS12455
gene id: 1618207:UM93_RS12455
uniprot id: A0A0D4C0L2
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS00790
gene id: 1618207:UM93_RS00790
uniprot id: A0A0D4BWE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1618207:UM93 RS06170
gene id: 1618207:UM93_RS06170
uniprot id: A0A0D4BY14
names: Similarity
messages: Belongs to the CdaR family.

1618207:UM93 RS06505
gene id: 1618207:UM93_RS06505
uniprot id: A0A0D4BXS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1618207:UM93 RS13345
gene id: 1618207:UM93_RS13345
uniprot id: A0A0D4C101
names: Similarity
messages: Belongs to the CsoR family.

1618207:UM93 RS05750
gene id: 1618207:UM93_RS05750
uniprot id: A0A0D4C2J4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1618207:UM93 RS10800
gene id: 1618207:UM93_RS10800
uniprot id: A0A0D4C0D4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1618207:UM93 RS16175
gene id: 1618207:UM93_RS16175
uniprot id: A0A0D4C2L4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1618207:UM93 RS09720
gene id: 1618207:UM93_RS09720
uniprot id: A0A0D4BZZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1618207:UM93 RS08355
gene id: 1618207:UM93_RS08355
uniprot id: A0A0D4BYM2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1618207:UM93 RS00775
gene id: 1618207:UM93_RS00775
uniprot id: A0A0D4C2Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1618207:UM93 RS03715
gene id: 1618207:UM93_RS03715
uniprot id: A0A0D4BXJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

1618207:UM93 RS06075
gene id: 1618207:UM93_RS06075
uniprot id: A0A0D4BXL0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1618207:UM93 RS16475
gene id: 1618207:UM93_RS16475
uniprot id: A0A0D4C1W7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1618207:UM93 RS08220
gene id: 1618207:UM93_RS08220
uniprot id: A0A0D4BYY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1618207:UM93 RS03240
gene id: 1618207:UM93_RS03240
uniprot id: A0A0D4BXC8
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS07760
gene id: 1618207:UM93_RS07760
uniprot id: A0A0D4BYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1618207:UM93 RS09760
gene id: 1618207:UM93_RS09760
uniprot id: A0A0D4C047
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1618207:UM93 RS02425
gene id: 1618207:UM93_RS02425
uniprot id: A0A0D4BWI1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS00335
gene id: 1618207:UM93_RS00335
uniprot id: A0A0D4BVC0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1618207:UM93 RS04340
gene id: 1618207:UM93_RS04340
uniprot id: A0A0D4BXT6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1618207:UM93 RS06720
gene id: 1618207:UM93_RS06720
uniprot id: A0A0D4BY77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1618207:UM93 RS00020
gene id: 1618207:UM93_RS00020
uniprot id: A0A0D4C221
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1618207:UM93 RS16390
gene id: 1618207:UM93_RS16390
uniprot id: A0A0D4C290
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1618207:UM93 RS10215
gene id: 1618207:UM93_RS10215
uniprot id: A0A0D4C0B1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS13715
gene id: 1618207:UM93_RS13715
uniprot id: A0A0D4C151
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1618207:UM93 RS04540
gene id: 1618207:UM93_RS04540
uniprot id: A0A0D4BXB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1618207:UM93 RS00815
gene id: 1618207:UM93_RS00815
uniprot id: A0A0D4BVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1618207:UM93 RS12065
gene id: 1618207:UM93_RS12065
uniprot id: A0A0D4C0J4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1618207:UM93 RS06260
gene id: 1618207:UM93_RS06260
uniprot id: A0A0D4C2U4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1618207:UM93 RS13565
gene id: 1618207:UM93_RS13565
uniprot id: A0A0D4C131
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1618207:UM93 RS04970
gene id: 1618207:UM93_RS04970
uniprot id: A0A0D4BXJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1618207:UM93 RS11650
gene id: 1618207:UM93_RS11650
uniprot id: A0A0D4C0T9
names: Similarity
messages: Belongs to the AHA1 family.

1618207:UM93 RS00495
gene id: 1618207:UM93_RS00495
uniprot id: A0A0D4BVQ6
names: Similarity
messages: Belongs to the peptidase A24 family.

1618207:UM93 RS13560
gene id: 1618207:UM93_RS13560
uniprot id: A0A0D4C0Z2
names: Similarity
messages: Belongs to the thioredoxin family.

1618207:UM93 RS07410
gene id: 1618207:UM93_RS07410
uniprot id: A0A0D4BZ43
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1618207:UM93 RS12965
gene id: 1618207:UM93_RS12965
uniprot id: A0A0D4C0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1618207:UM93 RS05370
gene id: 1618207:UM93_RS05370
uniprot id: A0A0D4BY97
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1618207:UM93 RS04420
gene id: 1618207:UM93_RS04420
uniprot id: A0A0D4BX94
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1618207:UM93 RS03050
gene id: 1618207:UM93_RS03050
uniprot id: A0A0D4BX98
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1618207:UM93 RS05770
gene id: 1618207:UM93_RS05770
uniprot id: A0A0D4BXV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1618207:UM93 RS01565
gene id: 1618207:UM93_RS01565
uniprot id: A0A0D4BWR7
names: Similarity
messages: Belongs to the ribF family.

1618207:UM93 RS04415
gene id: 1618207:UM93_RS04415
uniprot id: A0A0D4BWU9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS06380
gene id: 1618207:UM93_RS06380
uniprot id: A0A0D4BYR3
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1618207:UM93 RS12015
gene id: 1618207:UM93_RS12015
uniprot id: A0A0D4C137
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1618207:UM93 RS04535
gene id: 1618207:UM93_RS04535
uniprot id: A0A0D4BWW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1618207:UM93 RS01910
gene id: 1618207:UM93_RS01910
uniprot id: A0A0D4BWB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1618207:UM93 RS13490
gene id: 1618207:UM93_RS13490
uniprot id: A0A0D4C0P9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1618207:UM93 RS05485
gene id: 1618207:UM93_RS05485
uniprot id: A0A0D4BYB2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1618207:UM93 RS06705
gene id: 1618207:UM93_RS06705
uniprot id: A0A0D4BYU8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1618207:UM93 RS11415
gene id: 1618207:UM93_RS11415
uniprot id: A0A0D4C0M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS06165
gene id: 1618207:UM93_RS06165
uniprot id: A0A0D4BXZ9
names: Similarity
messages: Belongs to the peptidase S51 family.

1618207:UM93 RS01795
gene id: 1618207:UM93_RS01795
uniprot id: A0A0D4BWA1
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

1618207:UM93 RS16645
gene id: 1618207:UM93_RS16645
uniprot id: A0A0D4C1Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1618207:UM93 RS01290
gene id: 1618207:UM93_RS01290
uniprot id: A0A0D4BW34
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS00235
gene id: 1618207:UM93_RS00235
uniprot id: A0A0D4BVN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS16485
gene id: 1618207:UM93_RS16485
uniprot id: A0A0D4C255
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1618207:UM93 RS11455
gene id: 1618207:UM93_RS11455
uniprot id: A0A0D4C0S6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1618207:UM93 RS01950
gene id: 1618207:UM93_RS01950
uniprot id: A0A0D4BWW6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1618207:UM93 RS09770
gene id: 1618207:UM93_RS09770
uniprot id: A0A0D4BZH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1618207:UM93 RS04990
gene id: 1618207:UM93_RS04990
uniprot id: A0A0D4BY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1618207:UM93 RS01680
gene id: 1618207:UM93_RS01680
uniprot id: A0A0D4BWT7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1618207:UM93 RS14245
gene id: 1618207:UM93_RS14245
uniprot id: A0A0D4C1D0
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS03820
gene id: 1618207:UM93_RS03820
uniprot id: A0A0D4BXJ3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1618207:UM93 RS13530
gene id: 1618207:UM93_RS13530
uniprot id: A0A0D4C0Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1618207:UM93 RS01675
gene id: 1618207:UM93_RS01675
uniprot id: A0A0D4BWS6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS03495
gene id: 1618207:UM93_RS03495
uniprot id: A0A0D4BXF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1618207:UM93 RS09880
gene id: 1618207:UM93_RS09880
uniprot id: A0A0D4C066
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1618207:UM93 RS07530
gene id: 1618207:UM93_RS07530
uniprot id: A0A0D4BYK1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS03780
gene id: 1618207:UM93_RS03780
uniprot id: A0A0D4C2D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1618207:UM93 RS02905
gene id: 1618207:UM93_RS02905
uniprot id: A0A0D4BWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1618207:UM93 RS16335
gene id: 1618207:UM93_RS16335
uniprot id: A0A0D4C1U7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1618207:UM93 RS04930
gene id: 1618207:UM93_RS04930
uniprot id: A0A0D4BY30
names: Similarity
messages: Belongs to the peptidase M13 family.

1618207:UM93 RS13240
gene id: 1618207:UM93_RS13240
uniprot id: A0A0D4C1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS15830
gene id: 1618207:UM93_RS15830
uniprot id: A0A0D4C1P3
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS16745
gene id: 1618207:UM93_RS16745
uniprot id: A0A0D4C2W6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1618207:UM93 RS12045
gene id: 1618207:UM93_RS12045
uniprot id: A0A0D4C142
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS06800
gene id: 1618207:UM93_RS06800
uniprot id: A0A0D4BYA4
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS15210
gene id: 1618207:UM93_RS15210
uniprot id: A0A0D4C1U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1618207:UM93 RS00700
gene id: 1618207:UM93_RS00700
uniprot id: A0A0D4BVU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1618207:UM93 RS06180
gene id: 1618207:UM93_RS06180
uniprot id: A0A0D4BYM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1618207:UM93 RS03490
gene id: 1618207:UM93_RS03490
uniprot id: A0A0D4BWW2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1618207:UM93 RS14830
gene id: 1618207:UM93_RS14830
uniprot id: A0A0D4C251
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1618207:UM93 RS11915
gene id: 1618207:UM93_RS11915
uniprot id: A0A0D4C0X3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1618207:UM93 RS13700
gene id: 1618207:UM93_RS13700
uniprot id: A0A0D4C1P2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1618207:UM93 RS01440
gene id: 1618207:UM93_RS01440
uniprot id: A0A0D4BVU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1618207:UM93 RS12285
gene id: 1618207:UM93_RS12285
uniprot id: A0A0D4C0I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1618207:UM93 RS14045
gene id: 1618207:UM93_RS14045
uniprot id: A0A0D4C0W6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1618207:UM93 RS09970
gene id: 1618207:UM93_RS09970
uniprot id: A0A0D4C029
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1618207:UM93 RS00165
gene id: 1618207:UM93_RS00165
uniprot id: A0A0D4BVL9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1618207:UM93 RS15250
gene id: 1618207:UM93_RS15250
uniprot id: A0A0D4C2A0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1618207:UM93 RS04885
gene id: 1618207:UM93_RS04885
uniprot id: A0A0D4BX54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1618207:UM93 RS02865
gene id: 1618207:UM93_RS02865
uniprot id: A0A0D4BWL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS10025
gene id: 1618207:UM93_RS10025
uniprot id: A0A0D4BZA1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1618207:UM93 RS13545
gene id: 1618207:UM93_RS13545
uniprot id: A0A0D4C1M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1618207:UM93 RS00295
gene id: 1618207:UM93_RS00295
uniprot id: A0A0D4BW74
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1618207:UM93 RS04935
gene id: 1618207:UM93_RS04935
uniprot id: A0A0D4BY55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1618207:UM93 RS05680
gene id: 1618207:UM93_RS05680
uniprot id: A0A0D4BXU6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1618207:UM93 RS12400
gene id: 1618207:UM93_RS12400
uniprot id: A0A0D4C135
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1618207:UM93 RS08475
gene id: 1618207:UM93_RS08475
uniprot id: A0A0D4BZ17
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS06420
gene id: 1618207:UM93_RS06420
uniprot id: A0A0D4BY37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1618207:UM93 RS03650
gene id: 1618207:UM93_RS03650
uniprot id: A0A0D4BWJ5
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS00825
gene id: 1618207:UM93_RS00825
uniprot id: A0A0D4BWF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1618207:UM93 RS07155
gene id: 1618207:UM93_RS07155
uniprot id: A0A0D4BYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1618207:UM93 RS09700
gene id: 1618207:UM93_RS09700
uniprot id: A0A0D4BZ52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1618207:UM93 RS09840
gene id: 1618207:UM93_RS09840
uniprot id: A0A0D4BZJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1618207:UM93 RS02575
gene id: 1618207:UM93_RS02575
uniprot id: A0A0D4BX35
names: Similarity
messages: Belongs to the YciI family.

1618207:UM93 RS04255
gene id: 1618207:UM93_RS04255
uniprot id: A0A0D4BX65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1618207:UM93 RS04735
gene id: 1618207:UM93_RS04735
uniprot id: A0A0D4BXZ1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS16290
gene id: 1618207:UM93_RS16290
uniprot id: A0A0D4C2M9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1618207:UM93 RS03055
gene id: 1618207:UM93_RS03055
uniprot id: A0A0D4BXB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1618207:UM93 RS05445
gene id: 1618207:UM93_RS05445
uniprot id: A0A0D4C3B7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1618207:UM93 RS11355
gene id: 1618207:UM93_RS11355
uniprot id: A0A0D4C3W8
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS15640
gene id: 1618207:UM93_RS15640
uniprot id: A0A0D4C1V5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1618207:UM93 RS12030
gene id: 1618207:UM93_RS12030
uniprot id: A0A0D4C0F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1618207:UM93 RS00730
gene id: 1618207:UM93_RS00730
uniprot id: A0A0D4BVU0
names: Similarity
messages: Belongs to the CdaR family.

1618207:UM93 RS09310
gene id: 1618207:UM93_RS09310
uniprot id: A0A0D4BYZ1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1618207:UM93 RS02545
gene id: 1618207:UM93_RS02545
uniprot id: A0A0D4BW49
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1618207:UM93 RS16730
gene id: 1618207:UM93_RS16730
uniprot id: A0A0D4C2D5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1618207:UM93 RS01180
gene id: 1618207:UM93_RS01180
uniprot id: A0A0D4BW17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1618207:UM93 RS10325
gene id: 1618207:UM93_RS10325
uniprot id: A0A0D4C0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1618207:UM93 RS02745
gene id: 1618207:UM93_RS02745
uniprot id: A0A0D4C2A8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1618207:UM93 RS05975
gene id: 1618207:UM93_RS05975
uniprot id: A0A0D4BYH2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1618207:UM93 RS06785
gene id: 1618207:UM93_RS06785
uniprot id: A0A0D4BYV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1618207:UM93 RS10515
gene id: 1618207:UM93_RS10515
uniprot id: A0A0D4C3E1
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS05285
gene id: 1618207:UM93_RS05285
uniprot id: A0A0D4BXB6
names: Similarity
messages: Belongs to the AHA1 family.

1618207:UM93 RS09990
gene id: 1618207:UM93_RS09990
uniprot id: A0A0D4BZL0
names: Subcellular Location Annotation
messages: Membrane

1618207:UM93 RS04090
gene id: 1618207:UM93_RS04090
uniprot id: A0A0D4BXP6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1618207:UM93 RS02850
gene id: 1618207:UM93_RS02850
uniprot id: A0A0D4BX64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1618207:UM93 RS01875
gene id: 1618207:UM93_RS01875
uniprot id: A0A0D4C347
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1618207:UM93 RS09565
gene id: 1618207:UM93_RS09565
uniprot id: A0A0D4BZ30
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1618207:UM93 RS07895
gene id: 1618207:UM93_RS07895
uniprot id: A0A0D4BYP0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1618207:UM93 RS04660
gene id: 1618207:UM93_RS04660
uniprot id: A0A0D4BWY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1618207:UM93 RS07220
gene id: 1618207:UM93_RS07220
uniprot id: A0A0D4BYF9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1618207:UM93 RS13720
gene id: 1618207:UM93_RS13720
uniprot id: A0A0D4C1K8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1618207:UM93 RS04355
gene id: 1618207:UM93_RS04355
uniprot id: A0A0D4BX80
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1618207:UM93 RS00105
gene id: 1618207:UM93_RS00105
uniprot id: A0A0D4BVM0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.