1609559:TQ32 RS05820
gene id: 1609559:TQ32_RS05820
uniprot id: A0A127B9N5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

1609559:TQ32 RS03965
gene id: 1609559:TQ32_RS03965
uniprot id: A0A127B8L9
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS03355
gene id: 1609559:TQ32_RS03355
uniprot id: A0A127BAD3
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

1609559:TQ32 RS02160
gene id: 1609559:TQ32_RS02160
uniprot id: A0A127B7R6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1609559:TQ32 RS01325
gene id: 1609559:TQ32_RS01325
uniprot id: A0A127B7X5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS04345
gene id: 1609559:TQ32_RS04345
uniprot id: A0A127BAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS00820
gene id: 1609559:TQ32_RS00820
uniprot id: A0A127B7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS04325
gene id: 1609559:TQ32_RS04325
uniprot id: A0A127B8U3
names: Similarity
messages: Belongs to the ZPR1 family.

1609559:TQ32 RS05880
gene id: 1609559:TQ32_RS05880
uniprot id: A0A127BB73
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

1609559:TQ32 RS01170
gene id: 1609559:TQ32_RS01170
uniprot id: A0A127B775
names: Similarity
messages: Belongs to the UPF0147 family.

1609559:TQ32 RS08885
gene id: 1609559:TQ32_RS08885
uniprot id: A0A127BB65
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1609559:TQ32 RS05845
gene id: 1609559:TQ32_RS05845
uniprot id: A0A127B9I7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS06270
gene id: 1609559:TQ32_RS06270
uniprot id: A0A127B9U3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1609559:TQ32 RS04910
gene id: 1609559:TQ32_RS04910
uniprot id: A0A127B961
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1609559:TQ32 RS05545
gene id: 1609559:TQ32_RS05545
uniprot id: A0A127BBG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1609559:TQ32 RS01275
gene id: 1609559:TQ32_RS01275
uniprot id: A0A127B7M8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1609559:TQ32 RS06555
gene id: 1609559:TQ32_RS06555
uniprot id: A0A127BA01
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS00895
gene id: 1609559:TQ32_RS00895
uniprot id: A0A127B7G4
names: Similarity
messages: Belongs to the acylphosphatase family.

1609559:TQ32 RS07125
gene id: 1609559:TQ32_RS07125
uniprot id: A0A127BAJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS08840
gene id: 1609559:TQ32_RS08840
uniprot id: A0A127BBJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm

1609559:TQ32 RS09410
gene id: 1609559:TQ32_RS09410
uniprot id: A0A127BBF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1609559:TQ32 RS08745
gene id: 1609559:TQ32_RS08745
uniprot id: A0A127BB37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

1609559:TQ32 RS03465
gene id: 1609559:TQ32_RS03465
uniprot id: A0A127B8X5
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

1609559:TQ32 RS10885
gene id: 1609559:TQ32_RS10885
uniprot id: A0A127BC56
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS09285
gene id: 1609559:TQ32_RS09285
uniprot id: A0A127BCW9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1609559:TQ32 RS09195
gene id: 1609559:TQ32_RS09195
uniprot id: A0A127BBB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1609559:TQ32 RS05115
gene id: 1609559:TQ32_RS05115
uniprot id: A0A127B9E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1609559:TQ32 RS04555
gene id: 1609559:TQ32_RS04555
uniprot id: A0A127B9F5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1609559:TQ32 RS10040
gene id: 1609559:TQ32_RS10040
uniprot id: A0A127BBT3
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS10580
gene id: 1609559:TQ32_RS10580
uniprot id: A0A127BC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1609559:TQ32 RS10695
gene id: 1609559:TQ32_RS10695
uniprot id: A0A127BDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

1609559:TQ32 RS02295
gene id: 1609559:TQ32_RS02295
uniprot id: A0A127B9V3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1609559:TQ32 RS00220
gene id: 1609559:TQ32_RS00220
uniprot id: A0A127B6T2
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

1609559:TQ32 RS00245
gene id: 1609559:TQ32_RS00245
uniprot id: A0A127B745
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1609559:TQ32 RS05120
gene id: 1609559:TQ32_RS05120
uniprot id: A0A127B9M5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1609559:TQ32 RS05415
gene id: 1609559:TQ32_RS05415
uniprot id: A0A127BBE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1609559:TQ32 RS10585
gene id: 1609559:TQ32_RS10585
uniprot id: A0A127BDI8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1609559:TQ32 RS00730
gene id: 1609559:TQ32_RS00730
uniprot id: A0A127B8R8
names: Function
messages: Part of a potassium transport system.

1609559:TQ32 RS00190
gene id: 1609559:TQ32_RS00190
uniprot id: A0A127B736
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1609559:TQ32 RS00845
gene id: 1609559:TQ32_RS00845
uniprot id: A0A127B8T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal-type GPI family.
messages: Cytoplasm
messages: Homodimer.

1609559:TQ32 RS07615
gene id: 1609559:TQ32_RS07615
uniprot id: A0A127BAK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

1609559:TQ32 RS00410
gene id: 1609559:TQ32_RS00410
uniprot id: A0A127B783
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS05245
gene id: 1609559:TQ32_RS05245
uniprot id: A0A127BBB6
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS10060
gene id: 1609559:TQ32_RS10060
uniprot id: A0A127BC01
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS03015
gene id: 1609559:TQ32_RS03015
uniprot id: A0A127B865
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1609559:TQ32 RS09190
gene id: 1609559:TQ32_RS09190
uniprot id: A0A127BBB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1609559:TQ32 RS01865
gene id: 1609559:TQ32_RS01865
uniprot id: A0A127B7Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1609559:TQ32 RS00445
gene id: 1609559:TQ32_RS00445
uniprot id: A0A127B6X8
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1609559:TQ32 RS06940
gene id: 1609559:TQ32_RS06940
uniprot id: A0A127BA78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS02080
gene id: 1609559:TQ32_RS02080
uniprot id: A0A127B813
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1609559:TQ32 RS06670
gene id: 1609559:TQ32_RS06670
uniprot id: A0A127BBL1
names: Similarity
messages: Belongs to the UPF0215 family.

1609559:TQ32 RS05005
gene id: 1609559:TQ32_RS05005
uniprot id: A0A127B9J9
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS08470
gene id: 1609559:TQ32_RS08470
uniprot id: A0A127BAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1609559:TQ32 RS07470
gene id: 1609559:TQ32_RS07470
uniprot id: A0A127BC00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1609559:TQ32 RS09265
gene id: 1609559:TQ32_RS09265
uniprot id: A0A127BBS2
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07025
gene id: 1609559:TQ32_RS07025
uniprot id: A0A127BA79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1609559:TQ32 RS02115
gene id: 1609559:TQ32_RS02115
uniprot id: A0A127B812
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1609559:TQ32 RS00435
gene id: 1609559:TQ32_RS00435
uniprot id: A0A127B8L3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

1609559:TQ32 RS00040
gene id: 1609559:TQ32_RS00040
uniprot id: A0A127B748
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

1609559:TQ32 RS08820
gene id: 1609559:TQ32_RS08820
uniprot id: A0A127BB39
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1609559:TQ32 RS08695
gene id: 1609559:TQ32_RS08695
uniprot id: A0A127BCL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1609559:TQ32 RS08260
gene id: 1609559:TQ32_RS08260
uniprot id: A0A127BBA0
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS05840
gene id: 1609559:TQ32_RS05840
uniprot id: A0A127B9K2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS03365
gene id: 1609559:TQ32_RS03365
uniprot id: A0A127B8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1609559:TQ32 RS02800
gene id: 1609559:TQ32_RS02800
uniprot id: A0A127B9S9
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1609559:TQ32 RS03595
gene id: 1609559:TQ32_RS03595
uniprot id: A0A127BCA4
names: Similarity
messages: Belongs to the UPF0107 family.

1609559:TQ32 RS03065
gene id: 1609559:TQ32_RS03065
uniprot id: A0A127B8G6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1609559:TQ32 RS07110
gene id: 1609559:TQ32_RS07110
uniprot id: A0A127BAB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1609559:TQ32 RS04670
gene id: 1609559:TQ32_RS04670
uniprot id: A0A127BCP1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS07100
gene id: 1609559:TQ32_RS07100
uniprot id: A0A127BAA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1609559:TQ32 RS08670
gene id: 1609559:TQ32_RS08670
uniprot id: A0A127BBG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1609559:TQ32 RS00655
gene id: 1609559:TQ32_RS00655
uniprot id: A0A127B7L3
names: Similarity
messages: Belongs to the peptidase U62 family.

1609559:TQ32 RS09945
gene id: 1609559:TQ32_RS09945
uniprot id: A0A127BC37
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS08335
gene id: 1609559:TQ32_RS08335
uniprot id: A0A127BCE9
names: Similarity
messages: Belongs to the UPF0292 family.

1609559:TQ32 RS10405
gene id: 1609559:TQ32_RS10405
uniprot id: A0A127BEE3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1609559:TQ32 RS07660
gene id: 1609559:TQ32_RS07660
uniprot id: A0A127BAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1609559:TQ32 RS04770
gene id: 1609559:TQ32_RS04770
uniprot id: A0A127B9F7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1609559:TQ32 RS02090
gene id: 1609559:TQ32_RS02090
uniprot id: A0A127B7Q5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1609559:TQ32 RS01090
gene id: 1609559:TQ32_RS01090
uniprot id: A0A127B7M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1609559:TQ32 RS09275
gene id: 1609559:TQ32_RS09275
uniprot id: A0A127BBL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

1609559:TQ32 RS02265
gene id: 1609559:TQ32_RS02265
uniprot id: A0A127B7T5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1609559:TQ32 RS01045
gene id: 1609559:TQ32_RS01045
uniprot id: A0A127B9B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1609559:TQ32 RS01290
gene id: 1609559:TQ32_RS01290
uniprot id: A0A127B7B1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1609559:TQ32 RS09335
gene id: 1609559:TQ32_RS09335
uniprot id: A0A127BBE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS09355
gene id: 1609559:TQ32_RS09355
uniprot id: A0A127BCG8
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1609559:TQ32 RS06195
gene id: 1609559:TQ32_RS06195
uniprot id: A0A127B9V7
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS08740
gene id: 1609559:TQ32_RS08740
uniprot id: A0A127BBB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

1609559:TQ32 RS03570
gene id: 1609559:TQ32_RS03570
uniprot id: A0A127BAH0
names: Subcellular Location Annotation
messages: Nucleus

1609559:TQ32 RS09655
gene id: 1609559:TQ32_RS09655
uniprot id: A0A127BBJ6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1609559:TQ32 RS01040
gene id: 1609559:TQ32_RS01040
uniprot id: A0A127B7J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers.

1609559:TQ32 RS00745
gene id: 1609559:TQ32_RS00745
uniprot id: A0A127B722
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS09705
gene id: 1609559:TQ32_RS09705
uniprot id: A0A127BD31
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1609559:TQ32 RS00415
gene id: 1609559:TQ32_RS00415
uniprot id: A0A127B7A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS01115
gene id: 1609559:TQ32_RS01115
uniprot id: A0A127B8Z0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS05790
gene id: 1609559:TQ32_RS05790
uniprot id: A0A127B9J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1609559:TQ32 RS04245
gene id: 1609559:TQ32_RS04245
uniprot id: A0A127B9B3
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

1609559:TQ32 RS09860
gene id: 1609559:TQ32_RS09860
uniprot id: A0A127BBN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS05965
gene id: 1609559:TQ32_RS05965
uniprot id: A0A127B9U1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

1609559:TQ32 RS04270
gene id: 1609559:TQ32_RS04270
uniprot id: A0A127B8S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

1609559:TQ32 RS10260
gene id: 1609559:TQ32_RS10260
uniprot id: A0A127BBV5
names: Similarity
messages: Belongs to the UPF0252 family.

1609559:TQ32 RS00775
gene id: 1609559:TQ32_RS00775
uniprot id: A0A127B983
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1609559:TQ32 RS05565
gene id: 1609559:TQ32_RS05565
uniprot id: A0A127B9F8
names: Similarity
messages: Belongs to the UPF0282 family.

1609559:TQ32 RS09045
gene id: 1609559:TQ32_RS09045
uniprot id: A0A127BBN3
names: Similarity
messages: Belongs to the peptidase S49 family.

1609559:TQ32 RS01250
gene id: 1609559:TQ32_RS01250
uniprot id: A0A127B7A5
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.
messages: Belongs to the SIS family. PHI subfamily.

1609559:TQ32 RS00020
gene id: 1609559:TQ32_RS00020
uniprot id: A0A127B6N5
names: Similarity
messages: Belongs to the UPF0273 family.

1609559:TQ32 RS07340
gene id: 1609559:TQ32_RS07340
uniprot id: A0A127BAU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1609559:TQ32 RS00600
gene id: 1609559:TQ32_RS00600
uniprot id: A0A127B7B9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1609559:TQ32 RS03475
gene id: 1609559:TQ32_RS03475
uniprot id: A0A127BA20
names: Similarity
messages: Belongs to the arginase family.

1609559:TQ32 RS01860
gene id: 1609559:TQ32_RS01860
uniprot id: A0A127B7L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1609559:TQ32 RS09055
gene id: 1609559:TQ32_RS09055
uniprot id: A0A127BBH7
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1609559:TQ32 RS07170
gene id: 1609559:TQ32_RS07170
uniprot id: A0A127BAB7
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS03955
gene id: 1609559:TQ32_RS03955
uniprot id: A0A127B8M9
names: Similarity
messages: Belongs to the NodU/CmcH family.

1609559:TQ32 RS02715
gene id: 1609559:TQ32_RS02715
uniprot id: A0A127B8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS04305
gene id: 1609559:TQ32_RS04305
uniprot id: A0A127BAF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1609559:TQ32 RS02320
gene id: 1609559:TQ32_RS02320
uniprot id: A0A127B7V9
names: Similarity
messages: Belongs to the UPF0175 family.

1609559:TQ32 RS04870
gene id: 1609559:TQ32_RS04870
uniprot id: A0A127B926
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1609559:TQ32 RS09455
gene id: 1609559:TQ32_RS09455
uniprot id: A0A127BBG8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1609559:TQ32 RS07990
gene id: 1609559:TQ32_RS07990
uniprot id: A0A127BAQ2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1609559:TQ32 RS05210
gene id: 1609559:TQ32_RS05210
uniprot id: A0A127B999
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS00865
gene id: 1609559:TQ32_RS00865
uniprot id: A0A127B750
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS07085
gene id: 1609559:TQ32_RS07085
uniprot id: A0A127BBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1609559:TQ32 RS07205
gene id: 1609559:TQ32_RS07205
uniprot id: A0A127BAB0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1609559:TQ32 RS09050
gene id: 1609559:TQ32_RS09050
uniprot id: A0A127BD57
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1609559:TQ32 RS00105
gene id: 1609559:TQ32_RS00105
uniprot id: A0A127B728
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07015
gene id: 1609559:TQ32_RS07015
uniprot id: A0A127BA90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1609559:TQ32 RS01695
gene id: 1609559:TQ32_RS01695
uniprot id: A0A127BC83
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1609559:TQ32 RS01720
gene id: 1609559:TQ32_RS01720
uniprot id: A0A127B9P0
names: Similarity
messages: Belongs to the UPF0440 family.

1609559:TQ32 RS08015
gene id: 1609559:TQ32_RS08015
uniprot id: A0A127BCM5
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS00755
gene id: 1609559:TQ32_RS00755
uniprot id: A0A127B734
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1609559:TQ32 RS04835
gene id: 1609559:TQ32_RS04835
uniprot id: A0A127BB45
names: Similarity
messages: Belongs to the UPF0252 family.

1609559:TQ32 RS02230
gene id: 1609559:TQ32_RS02230
uniprot id: A0A127B7S3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS00515
gene id: 1609559:TQ32_RS00515
uniprot id: A0A127B6Z2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS07750
gene id: 1609559:TQ32_RS07750
uniprot id: A0A127BCI5
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1609559:TQ32 RS08430
gene id: 1609559:TQ32_RS08430
uniprot id: A0A127BBC7
names: Similarity
messages: Belongs to the class-I fumarase family.

1609559:TQ32 RS07635
gene id: 1609559:TQ32_RS07635
uniprot id: A0A127BAI9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

1609559:TQ32 RS03605
gene id: 1609559:TQ32_RS03605
uniprot id: A0A127B8G7
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.

1609559:TQ32 RS02275
gene id: 1609559:TQ32_RS02275
uniprot id: A0A127B7T3
names: Function
names: Similarity
messages: Belongs to the UPF0330 family.
messages: Possibly the antitoxin component of a toxin-antitoxin (TA) module.

1609559:TQ32 RS08005
gene id: 1609559:TQ32_RS08005
uniprot id: A0A127BAS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1609559:TQ32 RS07715
gene id: 1609559:TQ32_RS07715
uniprot id: A0A127BEB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1609559:TQ32 RS10010
gene id: 1609559:TQ32_RS10010
uniprot id: A0A127BBZ0
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1609559:TQ32 RS07320
gene id: 1609559:TQ32_RS07320
uniprot id: A0A127BAE3
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS05595
gene id: 1609559:TQ32_RS05595
uniprot id: A0A127B9W4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS00385
gene id: 1609559:TQ32_RS00385
uniprot id: A0A127B6W1
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

1609559:TQ32 RS09815
gene id: 1609559:TQ32_RS09815
uniprot id: A0A127BBM6
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS03195
gene id: 1609559:TQ32_RS03195
uniprot id: A0A127B896
names: Subcellular Location Annotation
messages: Cytoplasm

1609559:TQ32 RS01625
gene id: 1609559:TQ32_RS01625
uniprot id: A0A127B977
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1609559:TQ32 RS03215
gene id: 1609559:TQ32_RS03215
uniprot id: A0A127B8I6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1609559:TQ32 RS05870
gene id: 1609559:TQ32_RS05870
uniprot id: A0A127B9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1609559:TQ32 RS01585
gene id: 1609559:TQ32_RS01585
uniprot id: A0A127B7I5
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1609559:TQ32 RS08000
gene id: 1609559:TQ32_RS08000
uniprot id: A0A127BAS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1609559:TQ32 RS01240
gene id: 1609559:TQ32_RS01240
uniprot id: A0A127B7D7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1609559:TQ32 RS08450
gene id: 1609559:TQ32_RS08450
uniprot id: A0A127BAY5
names: Similarity
messages: Belongs to the UPF0145 family.

1609559:TQ32 RS09070
gene id: 1609559:TQ32_RS09070
uniprot id: A0A127BB93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1609559:TQ32 RS03715
gene id: 1609559:TQ32_RS03715
uniprot id: A0A127BA48
names: Similarity
messages: Belongs to the GARS family.

1609559:TQ32 RS09885
gene id: 1609559:TQ32_RS09885
uniprot id: A0A127BBQ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS06160
gene id: 1609559:TQ32_RS06160
uniprot id: A0A127B9U2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

1609559:TQ32 RS02250
gene id: 1609559:TQ32_RS02250
uniprot id: A0A127B8C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1609559:TQ32 RS08735
gene id: 1609559:TQ32_RS08735
uniprot id: A0A127BCZ0
names: Similarity
messages: Belongs to the MEMO1 family.

1609559:TQ32 RS06120
gene id: 1609559:TQ32_RS06120
uniprot id: A0A127BCD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1609559:TQ32 RS08600
gene id: 1609559:TQ32_RS08600
uniprot id: A0A127BB18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS06840
gene id: 1609559:TQ32_RS06840
uniprot id: A0A127BA56
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1609559:TQ32 RS10240
gene id: 1609559:TQ32_RS10240
uniprot id: A0A127BDT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1609559:TQ32 RS04315
gene id: 1609559:TQ32_RS04315
uniprot id: A0A127B8U1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the N-terminal section; belongs to the MobA family.

1609559:TQ32 RS05510
gene id: 1609559:TQ32_RS05510
uniprot id: A0A127BB13
names: Similarity
messages: Belongs to the UPF0201 family.

1609559:TQ32 RS10560
gene id: 1609559:TQ32_RS10560
uniprot id: A0A127BCI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1609559:TQ32 RS08360
gene id: 1609559:TQ32_RS08360
uniprot id: A0A127BAX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1609559:TQ32 RS07780
gene id: 1609559:TQ32_RS07780
uniprot id: A0A127BAM7
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS01450
gene id: 1609559:TQ32_RS01450
uniprot id: A0A127B7Z6
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS03100
gene id: 1609559:TQ32_RS03100
uniprot id: A0A127B8G3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1609559:TQ32 RS07980
gene id: 1609559:TQ32_RS07980
uniprot id: A0A127BC92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1609559:TQ32 RS05465
gene id: 1609559:TQ32_RS05465
uniprot id: A0A127B9L6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1609559:TQ32 RS04275
gene id: 1609559:TQ32_RS04275
uniprot id: A0A127B8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1609559:TQ32 RS03970
gene id: 1609559:TQ32_RS03970
uniprot id: A0A127B8V3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS09700
gene id: 1609559:TQ32_RS09700
uniprot id: A0A127BBK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

1609559:TQ32 RS03950
gene id: 1609559:TQ32_RS03950
uniprot id: A0A127B8N1
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.

1609559:TQ32 RS04755
gene id: 1609559:TQ32_RS04755
uniprot id: A0A127B908
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS01100
gene id: 1609559:TQ32_RS01100
uniprot id: A0A127B9D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

1609559:TQ32 RS03160
gene id: 1609559:TQ32_RS03160
uniprot id: A0A127B8H3
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1609559:TQ32 RS00640
gene id: 1609559:TQ32_RS00640
uniprot id: A0A127B7B6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1609559:TQ32 RS09430
gene id: 1609559:TQ32_RS09430
uniprot id: A0A127BBV1
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07675
gene id: 1609559:TQ32_RS07675
uniprot id: A0A127BCS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

1609559:TQ32 RS03735
gene id: 1609559:TQ32_RS03735
uniprot id: A0A127B8H9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1609559:TQ32 RS07975
gene id: 1609559:TQ32_RS07975
uniprot id: A0A127BAQ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1609559:TQ32 RS04435
gene id: 1609559:TQ32_RS04435
uniprot id: A0A127B8W1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS10685
gene id: 1609559:TQ32_RS10685
uniprot id: A0A127BC98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

1609559:TQ32 RS02710
gene id: 1609559:TQ32_RS02710
uniprot id: A0A127B8L1
names: Similarity
messages: Belongs to the DtxR/MntR family.

1609559:TQ32 RS07700
gene id: 1609559:TQ32_RS07700
uniprot id: A0A127BC43
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1609559:TQ32 RS08200
gene id: 1609559:TQ32_RS08200
uniprot id: A0A127BCH0
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

1609559:TQ32 RS02150
gene id: 1609559:TQ32_RS02150
uniprot id: A0A127B7R3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1609559:TQ32 RS09670
gene id: 1609559:TQ32_RS09670
uniprot id: A0A127BCH1
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1609559:TQ32 RS09875
gene id: 1609559:TQ32_RS09875
uniprot id: A0A127BBN9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS03360
gene id: 1609559:TQ32_RS03360
uniprot id: A0A127B8U9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1609559:TQ32 RS03135
gene id: 1609559:TQ32_RS03135
uniprot id: A0A127B879
names: Similarity
messages: Belongs to the archaeal ATPase family.

1609559:TQ32 RS08825
gene id: 1609559:TQ32_RS08825
uniprot id: A0A127BB64
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1609559:TQ32 RS02215
gene id: 1609559:TQ32_RS02215
uniprot id: A0A127B7R9
names: Similarity
messages: Belongs to the AOR/FOR family.

1609559:TQ32 RS02470
gene id: 1609559:TQ32_RS02470
uniprot id: A0A127B9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

1609559:TQ32 RS09970
gene id: 1609559:TQ32_RS09970
uniprot id: A0A127BBQ5
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS09470
gene id: 1609559:TQ32_RS09470
uniprot id: A0A127BBI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1609559:TQ32 RS00125
gene id: 1609559:TQ32_RS00125
uniprot id: A0A127B6Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1609559:TQ32 RS07505
gene id: 1609559:TQ32_RS07505
uniprot id: A0A127BAX4
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS10395
gene id: 1609559:TQ32_RS10395
uniprot id: A0A127BDF4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1609559:TQ32 RS07010
gene id: 1609559:TQ32_RS07010
uniprot id: A0A127BAH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1609559:TQ32 RS09565
gene id: 1609559:TQ32_RS09565
uniprot id: A0A127BBR0
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1609559:TQ32 RS06210
gene id: 1609559:TQ32_RS06210
uniprot id: A0A127B9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS00860
gene id: 1609559:TQ32_RS00860
uniprot id: A0A127B758
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1609559:TQ32 RS10220
gene id: 1609559:TQ32_RS10220
uniprot id: A0A127BBW8
names: Similarity
messages: Belongs to the UPF0128 family.

1609559:TQ32 RS09830
gene id: 1609559:TQ32_RS09830
uniprot id: A0A127BBP5
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07935
gene id: 1609559:TQ32_RS07935
uniprot id: A0A127BAP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS05580
gene id: 1609559:TQ32_RS05580
uniprot id: A0A127B9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1609559:TQ32 RS03740
gene id: 1609559:TQ32_RS03740
uniprot id: A0A127B8S2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS03865
gene id: 1609559:TQ32_RS03865
uniprot id: A0A127B8Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1609559:TQ32 RS07005
gene id: 1609559:TQ32_RS07005
uniprot id: A0A127BC59
names: Function
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

1609559:TQ32 RS00195
gene id: 1609559:TQ32_RS00195
uniprot id: A0A127B782
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1609559:TQ32 RS04215
gene id: 1609559:TQ32_RS04215
uniprot id: A0A127B8T6
names: Similarity
messages: Belongs to the UPF0047 family.

1609559:TQ32 RS05935
gene id: 1609559:TQ32_RS05935
uniprot id: A0A127BB84
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1609559:TQ32 RS08955
gene id: 1609559:TQ32_RS08955
uniprot id: A0A127BB77
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS09340
gene id: 1609559:TQ32_RS09340
uniprot id: A0A127BCG9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS04395
gene id: 1609559:TQ32_RS04395
uniprot id: A0A127B932
names: Subcellular Location Annotation
messages: Cell membrane

1609559:TQ32 RS01080
gene id: 1609559:TQ32_RS01080
uniprot id: A0A127B778
names: Similarity
messages: Belongs to the UPF0045 family.

1609559:TQ32 RS03930
gene id: 1609559:TQ32_RS03930
uniprot id: A0A127B948
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1609559:TQ32 RS09220
gene id: 1609559:TQ32_RS09220
uniprot id: A0A127BD88
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1609559:TQ32 RS07910
gene id: 1609559:TQ32_RS07910
uniprot id: A0A127BCK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1609559:TQ32 RS09570
gene id: 1609559:TQ32_RS09570
uniprot id: A0A127BBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1609559:TQ32 RS03070
gene id: 1609559:TQ32_RS03070
uniprot id: A0A127B9V4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1609559:TQ32 RS09750
gene id: 1609559:TQ32_RS09750
uniprot id: A0A127BBL8
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS01105
gene id: 1609559:TQ32_RS01105
uniprot id: A0A127B7U7
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

1609559:TQ32 RS10425
gene id: 1609559:TQ32_RS10425
uniprot id: A0A127BBY2
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.

1609559:TQ32 RS01480
gene id: 1609559:TQ32_RS01480
uniprot id: A0A127B7E9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1609559:TQ32 RS04370
gene id: 1609559:TQ32_RS04370
uniprot id: A0A127B8V1
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1609559:TQ32 RS08310
gene id: 1609559:TQ32_RS08310
uniprot id: A0A127BBA7
names: Similarity
messages: Belongs to the peptidase C56 family.

1609559:TQ32 RS05865
gene id: 1609559:TQ32_RS05865
uniprot id: A0A127BBL7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

1609559:TQ32 RS07950
gene id: 1609559:TQ32_RS07950
uniprot id: A0A127BAR6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1609559:TQ32 RS04990
gene id: 1609559:TQ32_RS04990
uniprot id: A0A127B953
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

1609559:TQ32 RS04865
gene id: 1609559:TQ32_RS04865
uniprot id: A0A127B929
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

1609559:TQ32 RS09730
gene id: 1609559:TQ32_RS09730
uniprot id: A0A127BBL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS10515
gene id: 1609559:TQ32_RS10515
uniprot id: A0A127BDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1609559:TQ32 RS07095
gene id: 1609559:TQ32_RS07095
uniprot id: A0A127BA96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1609559:TQ32 RS08325
gene id: 1609559:TQ32_RS08325
uniprot id: A0A127BCF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1609559:TQ32 RS09320
gene id: 1609559:TQ32_RS09320
uniprot id: A0A127BBT0
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1609559:TQ32 RS05255
gene id: 1609559:TQ32_RS05255
uniprot id: A0A127B9Q5
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS02310
gene id: 1609559:TQ32_RS02310
uniprot id: A0A127B854
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1609559:TQ32 RS01805
gene id: 1609559:TQ32_RS01805
uniprot id: A0A127B7X3
names: Similarity
messages: Belongs to the archaeal ATPase family.

1609559:TQ32 RS09550
gene id: 1609559:TQ32_RS09550
uniprot id: A0A127BBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1609559:TQ32 RS10100
gene id: 1609559:TQ32_RS10100
uniprot id: A0A127BC63
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

1609559:TQ32 RS01980
gene id: 1609559:TQ32_RS01980
uniprot id: A0A127B7N7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.
messages: Cytoplasm
messages: Homodimer.

1609559:TQ32 RS10815
gene id: 1609559:TQ32_RS10815
uniprot id: A0A127BDM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

1609559:TQ32 RS07330
gene id: 1609559:TQ32_RS07330
uniprot id: A0A127BAE9
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1609559:TQ32 RS00210
gene id: 1609559:TQ32_RS00210
uniprot id: A0A127B754
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

1609559:TQ32 RS03150
gene id: 1609559:TQ32_RS03150
uniprot id: A0A127B874
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1609559:TQ32 RS05195
gene id: 1609559:TQ32_RS05195
uniprot id: A0A127B9H5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS09130
gene id: 1609559:TQ32_RS09130
uniprot id: A0A127BBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

1609559:TQ32 RS04595
gene id: 1609559:TQ32_RS04595
uniprot id: A0A127B957
names: Similarity
messages: Belongs to the UPF0047 family.

1609559:TQ32 RS03455
gene id: 1609559:TQ32_RS03455
uniprot id: A0A127B8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1609559:TQ32 RS00765
gene id: 1609559:TQ32_RS00765
uniprot id: A0A127B7G5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

1609559:TQ32 RS04825
gene id: 1609559:TQ32_RS04825
uniprot id: A0A127B9A0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1609559:TQ32 RS05640
gene id: 1609559:TQ32_RS05640
uniprot id: A0A127B9G9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1609559:TQ32 RS08815
gene id: 1609559:TQ32_RS08815
uniprot id: A0A127BB43
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1609559:TQ32 RS04780
gene id: 1609559:TQ32_RS04780
uniprot id: A0A127BB33
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS10460
gene id: 1609559:TQ32_RS10460
uniprot id: A0A127BBY8
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS04880
gene id: 1609559:TQ32_RS04880
uniprot id: A0A127B9H8
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1609559:TQ32 RS01505
gene id: 1609559:TQ32_RS01505
uniprot id: A0A127B807
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1609559:TQ32 RS01270
gene id: 1609559:TQ32_RS01270
uniprot id: A0A127B7X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1609559:TQ32 RS06785
gene id: 1609559:TQ32_RS06785
uniprot id: A0A127BAE0
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

1609559:TQ32 RS08255
gene id: 1609559:TQ32_RS08255
uniprot id: A0A127BAV7
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS09135
gene id: 1609559:TQ32_RS09135
uniprot id: A0A127BBC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1609559:TQ32 RS01855
gene id: 1609559:TQ32_RS01855
uniprot id: A0A127BCL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1609559:TQ32 RS01180
gene id: 1609559:TQ32_RS01180
uniprot id: A0A127B7D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1609559:TQ32 RS08075
gene id: 1609559:TQ32_RS08075
uniprot id: A0A127BB11
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1609559:TQ32 RS03860
gene id: 1609559:TQ32_RS03860
uniprot id: A0A127B8T9
names: Similarity
messages: Belongs to the AOR/FOR family.

1609559:TQ32 RS00405
gene id: 1609559:TQ32_RS00405
uniprot id: A0A127B6X7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

1609559:TQ32 RS10050
gene id: 1609559:TQ32_RS10050
uniprot id: A0A127BC53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS08725
gene id: 1609559:TQ32_RS08725
uniprot id: A0A127BB36
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1609559:TQ32 RS05680
gene id: 1609559:TQ32_RS05680
uniprot id: A0A127B9M0
names: Similarity
messages: Belongs to the PDCD5 family.

1609559:TQ32 RS01465
gene id: 1609559:TQ32_RS01465
uniprot id: A0A127B7D6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1609559:TQ32 RS04660
gene id: 1609559:TQ32_RS04660
uniprot id: A0A127B9H7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1609559:TQ32 RS03125
gene id: 1609559:TQ32_RS03125
uniprot id: A0A127B8H5
names: Similarity
messages: Belongs to the HupF/HypC family.

1609559:TQ32 RS06770
gene id: 1609559:TQ32_RS06770
uniprot id: A0A127BC25
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1609559:TQ32 RS01060
gene id: 1609559:TQ32_RS01060
uniprot id: A0A127B8X7
names: Similarity
messages: Belongs to the GbsR family.

1609559:TQ32 RS10665
gene id: 1609559:TQ32_RS10665
uniprot id: A0A127BC32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1609559:TQ32 RS01420
gene id: 1609559:TQ32_RS01420
uniprot id: A0A127B7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

1609559:TQ32 RS04635
gene id: 1609559:TQ32_RS04635
uniprot id: A0A127B8Y6
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

1609559:TQ32 RS02070
gene id: 1609559:TQ32_RS02070
uniprot id: A0A127B9T1
names: Similarity
messages: Belongs to the UPF0216 family.

1609559:TQ32 RS02200
gene id: 1609559:TQ32_RS02200
uniprot id: A0A127B834
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Membrane

1609559:TQ32 RS02500
gene id: 1609559:TQ32_RS02500
uniprot id: A0A127B9N8
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS10000
gene id: 1609559:TQ32_RS10000
uniprot id: A0A127BC44
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS00025
gene id: 1609559:TQ32_RS00025
uniprot id: A0A127B6P4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1609559:TQ32 RS06825
gene id: 1609559:TQ32_RS06825
uniprot id: A0A127BAJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1609559:TQ32 RS09300
gene id: 1609559:TQ32_RS09300
uniprot id: A0A127BBD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

1609559:TQ32 RS01365
gene id: 1609559:TQ32_RS01365
uniprot id: A0A127B7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1609559:TQ32 RS04175
gene id: 1609559:TQ32_RS04175
uniprot id: A0A127B8Z3
names: Subunit
messages: Homotetramer.

1609559:TQ32 RS00725
gene id: 1609559:TQ32_RS00725
uniprot id: A0A127B7F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

1609559:TQ32 RS01965
gene id: 1609559:TQ32_RS01965
uniprot id: A0A127B7N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1609559:TQ32 RS08665
gene id: 1609559:TQ32_RS08665
uniprot id: A0A127BB26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1609559:TQ32 RS06585
gene id: 1609559:TQ32_RS06585
uniprot id: A0A127BAF7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

1609559:TQ32 RS09170
gene id: 1609559:TQ32_RS09170
uniprot id: A0A127BD78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1609559:TQ32 RS02290
gene id: 1609559:TQ32_RS02290
uniprot id: A0A127B858
names: Similarity
messages: Belongs to the UPF0284 family.

1609559:TQ32 RS05430
gene id: 1609559:TQ32_RS05430
uniprot id: A0A127BB03
names: Similarity
messages: Belongs to the CutA family.

1609559:TQ32 RS10780
gene id: 1609559:TQ32_RS10780
uniprot id: A0A127BC54
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1609559:TQ32 RS05490
gene id: 1609559:TQ32_RS05490
uniprot id: A0A127B9T9
names: Similarity
messages: Belongs to the UPF0248 family.

1609559:TQ32 RS04100
gene id: 1609559:TQ32_RS04100
uniprot id: A0A127BAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS04680
gene id: 1609559:TQ32_RS04680
uniprot id: A0A127B906
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1609559:TQ32 RS03545
gene id: 1609559:TQ32_RS03545
uniprot id: A0A127B8E4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1609559:TQ32 RS09180
gene id: 1609559:TQ32_RS09180
uniprot id: A0A127BBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

1609559:TQ32 RS07625
gene id: 1609559:TQ32_RS07625
uniprot id: A0A127BCG6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

1609559:TQ32 RS09990
gene id: 1609559:TQ32_RS09990
uniprot id: A0A127BBS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S16 family.
messages: Membrane

1609559:TQ32 RS02370
gene id: 1609559:TQ32_RS02370
uniprot id: A0A127B864
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1609559:TQ32 RS03975
gene id: 1609559:TQ32_RS03975
uniprot id: A0A127B901
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1609559:TQ32 RS00855
gene id: 1609559:TQ32_RS00855
uniprot id: A0A127B739
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1609559:TQ32 RS04130
gene id: 1609559:TQ32_RS04130
uniprot id: A0A127B931
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS03285
gene id: 1609559:TQ32_RS03285
uniprot id: A0A127BAB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS09140
gene id: 1609559:TQ32_RS09140
uniprot id: A0A127BBB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1609559:TQ32 RS08960
gene id: 1609559:TQ32_RS08960
uniprot id: A0A127BCQ6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1609559:TQ32 RS01620
gene id: 1609559:TQ32_RS01620
uniprot id: A0A127B7T8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1609559:TQ32 RS08635
gene id: 1609559:TQ32_RS08635
uniprot id: A0A127BCK2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1609559:TQ32 RS06095
gene id: 1609559:TQ32_RS06095
uniprot id: A0A127B9Q6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS10150
gene id: 1609559:TQ32_RS10150
uniprot id: A0A127BBV8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

1609559:TQ32 RS00090
gene id: 1609559:TQ32_RS00090
uniprot id: A0A127B753
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

1609559:TQ32 RS00375
gene id: 1609559:TQ32_RS00375
uniprot id: A0A127B790
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1609559:TQ32 RS02435
gene id: 1609559:TQ32_RS02435
uniprot id: A0A127B9M3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1609559:TQ32 RS03625
gene id: 1609559:TQ32_RS03625
uniprot id: A0A127B8Q3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.

1609559:TQ32 RS09475
gene id: 1609559:TQ32_RS09475
uniprot id: A0A127BBH1
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07670
gene id: 1609559:TQ32_RS07670
uniprot id: A0A127BB04
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1609559:TQ32 RS10555
gene id: 1609559:TQ32_RS10555
uniprot id: A0A127BCD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1609559:TQ32 RS09095
gene id: 1609559:TQ32_RS09095
uniprot id: A0A127BBP3
names: Similarity
messages: Belongs to the peptidase U62 family.

1609559:TQ32 RS06540
gene id: 1609559:TQ32_RS06540
uniprot id: A0A127BAA3
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1609559:TQ32 RS06340
gene id: 1609559:TQ32_RS06340
uniprot id: A0A127B9Z4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1609559:TQ32 RS07140
gene id: 1609559:TQ32_RS07140
uniprot id: A0A127BBU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1609559:TQ32 RS02155
gene id: 1609559:TQ32_RS02155
uniprot id: A0A127B7R0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

1609559:TQ32 RS08010
gene id: 1609559:TQ32_RS08010
uniprot id: A0A127BB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

1609559:TQ32 RS01690
gene id: 1609559:TQ32_RS01690
uniprot id: A0A127B7J2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1609559:TQ32 RS01675
gene id: 1609559:TQ32_RS01675
uniprot id: A0A127B7U8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

1609559:TQ32 RS03845
gene id: 1609559:TQ32_RS03845
uniprot id: A0A127B8K6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS01630
gene id: 1609559:TQ32_RS01630
uniprot id: A0A127B7I0
names: Similarity
messages: Belongs to the MoaB/Mog family.

1609559:TQ32 RS08340
gene id: 1609559:TQ32_RS08340
uniprot id: A0A127BAW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

1609559:TQ32 RS07965
gene id: 1609559:TQ32_RS07965
uniprot id: A0A127BCL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS05375
gene id: 1609559:TQ32_RS05375
uniprot id: A0A127BAZ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

1609559:TQ32 RS10205
gene id: 1609559:TQ32_RS10205
uniprot id: A0A127BDC9
names: Similarity
messages: Belongs to the UPF0212 family.

1609559:TQ32 RS05205
gene id: 1609559:TQ32_RS05205
uniprot id: A0A127BAW1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS10640
gene id: 1609559:TQ32_RS10640
uniprot id: A0A127BC19
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS06870
gene id: 1609559:TQ32_RS06870
uniprot id: A0A127BCE5
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1609559:TQ32 RS07595
gene id: 1609559:TQ32_RS07595
uniprot id: A0A127BAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

1609559:TQ32 RS07525
gene id: 1609559:TQ32_RS07525
uniprot id: A0A127BC10
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1609559:TQ32 RS10445
gene id: 1609559:TQ32_RS10445
uniprot id: A0A127BBY6
names: Similarity
messages: Belongs to the archaeal ATPase family.

1609559:TQ32 RS04795
gene id: 1609559:TQ32_RS04795
uniprot id: A0A127BAP3
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1609559:TQ32 RS05095
gene id: 1609559:TQ32_RS05095
uniprot id: A0A127B989
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
messages: Contains two alpha-helical subdomains, with the 8-oxoguanine binding site located in a cleft at their interface. Contains a helix-hairpin-helix (HhH) structural motif and a Gly/Pro-rich sequence followed by a conserved Asp (HhH-GPD motif).
messages: DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS01670
gene id: 1609559:TQ32_RS01670
uniprot id: A0A127B828
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1609559:TQ32 RS08595
gene id: 1609559:TQ32_RS08595
uniprot id: A0A127BB01
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1609559:TQ32 RS03925
gene id: 1609559:TQ32_RS03925
uniprot id: A0A127BAN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1609559:TQ32 RS01565
gene id: 1609559:TQ32_RS01565
uniprot id: A0A127B970
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS09660
gene id: 1609559:TQ32_RS09660
uniprot id: A0A127BBL0
names: Similarity
messages: Belongs to the UPF0111 family.

1609559:TQ32 RS06490
gene id: 1609559:TQ32_RS06490
uniprot id: A0A127BA06
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1609559:TQ32 RS01615
gene id: 1609559:TQ32_RS01615
uniprot id: A0A127B820
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS10410
gene id: 1609559:TQ32_RS10410
uniprot id: A0A127BBX7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1609559:TQ32 RS06200
gene id: 1609559:TQ32_RS06200
uniprot id: A0A127BBD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1609559:TQ32 RS00715
gene id: 1609559:TQ32_RS00715
uniprot id: A0A127B974
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer. Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

1609559:TQ32 RS10025
gene id: 1609559:TQ32_RS10025
uniprot id: A0A127BBR8
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS02440
gene id: 1609559:TQ32_RS02440
uniprot id: A0A127B7X2
names: Similarity
messages: Belongs to the BtpA family.

1609559:TQ32 RS04690
gene id: 1609559:TQ32_RS04690
uniprot id: A0A127B903
names: Similarity
messages: Belongs to the UPF0111 family.

1609559:TQ32 RS09880
gene id: 1609559:TQ32_RS09880
uniprot id: A0A127BBQ1
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS10925
gene id: 1609559:TQ32_RS10925
uniprot id: A0A127BCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS05420
gene id: 1609559:TQ32_RS05420
uniprot id: A0A127B9S6
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1609559:TQ32 RS10870
gene id: 1609559:TQ32_RS10870
uniprot id: A0A127BCC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1609559:TQ32 RS02000
gene id: 1609559:TQ32_RS02000
uniprot id: A0A127B800
names: Similarity
messages: Belongs to the peptidase S9C family.

1609559:TQ32 RS02840
gene id: 1609559:TQ32_RS02840
uniprot id: A0A127B8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1609559:TQ32 RS03480
gene id: 1609559:TQ32_RS03480
uniprot id: A0A127B8F3
names: Similarity
messages: Belongs to the UPF0148 family.

1609559:TQ32 RS02235
gene id: 1609559:TQ32_RS02235
uniprot id: A0A127B830
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1609559:TQ32 RS05335
gene id: 1609559:TQ32_RS05335
uniprot id: A0A127B9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS00240
gene id: 1609559:TQ32_RS00240
uniprot id: A0A127B6U6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.

1609559:TQ32 RS02985
gene id: 1609559:TQ32_RS02985
uniprot id: A0A127B8H8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1609559:TQ32 RS07620
gene id: 1609559:TQ32_RS07620
uniprot id: A0A127BAZ4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

1609559:TQ32 RS05100
gene id: 1609559:TQ32_RS05100
uniprot id: A0A127B968
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

1609559:TQ32 RS04765
gene id: 1609559:TQ32_RS04765
uniprot id: A0A127B990
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1609559:TQ32 RS07070
gene id: 1609559:TQ32_RS07070
uniprot id: A0A127BC69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

1609559:TQ32 RS03980
gene id: 1609559:TQ32_RS03980
uniprot id: A0A127BAN9
names: Similarity
messages: Belongs to the UPF0166 family.

1609559:TQ32 RS01715
gene id: 1609559:TQ32_RS01715
uniprot id: A0A127B7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1609559:TQ32 RS07115
gene id: 1609559:TQ32_RS07115
uniprot id: A0A127BAP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1609559:TQ32 RS00650
gene id: 1609559:TQ32_RS00650
uniprot id: A0A127B962
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1609559:TQ32 RS02270
gene id: 1609559:TQ32_RS02270
uniprot id: A0A127B7T2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1609559:TQ32 RS07890
gene id: 1609559:TQ32_RS07890
uniprot id: A0A127BAP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1609559:TQ32 RS07850
gene id: 1609559:TQ32_RS07850
uniprot id: A0A127BB30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

1609559:TQ32 RS09620
gene id: 1609559:TQ32_RS09620
uniprot id: A0A127BDF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

1609559:TQ32 RS00810
gene id: 1609559:TQ32_RS00810
uniprot id: A0A127B742
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1609559:TQ32 RS09375
gene id: 1609559:TQ32_RS09375
uniprot id: A0A127BBF6
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1609559:TQ32 RS08540
gene id: 1609559:TQ32_RS08540
uniprot id: A0A127BB08
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1609559:TQ32 RS06735
gene id: 1609559:TQ32_RS06735
uniprot id: A0A127BEA9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

1609559:TQ32 RS05720
gene id: 1609559:TQ32_RS05720
uniprot id: A0A127B9P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1609559:TQ32 RS04020
gene id: 1609559:TQ32_RS04020
uniprot id: A0A127B8N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1609559:TQ32 RS00365
gene id: 1609559:TQ32_RS00365
uniprot id: A0A127B7F9
names: Subunit
messages: Homotetramer.

1609559:TQ32 RS00750
gene id: 1609559:TQ32_RS00750
uniprot id: A0A127B729
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1609559:TQ32 RS04095
gene id: 1609559:TQ32_RS04095
uniprot id: A0A127B8Z1
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1609559:TQ32 RS03635
gene id: 1609559:TQ32_RS03635
uniprot id: A0A127B8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

1609559:TQ32 RS07425
gene id: 1609559:TQ32_RS07425
uniprot id: A0A127BAG6
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1609559:TQ32 RS06275
gene id: 1609559:TQ32_RS06275
uniprot id: A0A127B9X2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1609559:TQ32 RS06335
gene id: 1609559:TQ32_RS06335
uniprot id: A0A127B9X0
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

1609559:TQ32 RS09000
gene id: 1609559:TQ32_RS09000
uniprot id: A0A127BD47
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1609559:TQ32 RS09270
gene id: 1609559:TQ32_RS09270
uniprot id: A0A127BD96
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1609559:TQ32 RS05630
gene id: 1609559:TQ32_RS05630
uniprot id: A0A127BCQ1
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS08235
gene id: 1609559:TQ32_RS08235
uniprot id: A0A127BAU2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1609559:TQ32 RS09645
gene id: 1609559:TQ32_RS09645
uniprot id: A0A127BDY7
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

1609559:TQ32 RS04380
gene id: 1609559:TQ32_RS04380
uniprot id: A0A127B8V0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1609559:TQ32 RS02145
gene id: 1609559:TQ32_RS02145
uniprot id: A0A127B9F4
names: Similarity
messages: Belongs to the CinA family.

1609559:TQ32 RS06550
gene id: 1609559:TQ32_RS06550
uniprot id: A0A127BBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1609559:TQ32 RS07145
gene id: 1609559:TQ32_RS07145
uniprot id: A0A127BAA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1609559:TQ32 RS08715
gene id: 1609559:TQ32_RS08715
uniprot id: A0A127BB41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1609559:TQ32 RS01050
gene id: 1609559:TQ32_RS01050
uniprot id: A0A127B7T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1609559:TQ32 RS03200
gene id: 1609559:TQ32_RS03200
uniprot id: A0A127B884
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS08915
gene id: 1609559:TQ32_RS08915
uniprot id: A0A127BB62
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

1609559:TQ32 RS06975
gene id: 1609559:TQ32_RS06975
uniprot id: A0A127BA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS08300
gene id: 1609559:TQ32_RS08300
uniprot id: A0A127BAX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1609559:TQ32 RS00420
gene id: 1609559:TQ32_RS00420
uniprot id: A0A127B925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS06025
gene id: 1609559:TQ32_RS06025
uniprot id: A0A127BBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1609559:TQ32 RS08520
gene id: 1609559:TQ32_RS08520
uniprot id: A0A127BAZ5
names: Similarity
messages: Belongs to the UPF0173 family.

1609559:TQ32 RS09325
gene id: 1609559:TQ32_RS09325
uniprot id: A0A127BDA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

1609559:TQ32 RS02220
gene id: 1609559:TQ32_RS02220
uniprot id: A0A127B7S7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1609559:TQ32 RS07235
gene id: 1609559:TQ32_RS07235
uniprot id: A0A127BAL2
names: Function
messages: Probably involved in the biogenesis of the ribosome.

1609559:TQ32 RS07400
gene id: 1609559:TQ32_RS07400
uniprot id: A0A127BAP5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1609559:TQ32 RS03325
gene id: 1609559:TQ32_RS03325
uniprot id: A0A127B8A8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1609559:TQ32 RS07290
gene id: 1609559:TQ32_RS07290
uniprot id: A0A127BCG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

1609559:TQ32 RS03190
gene id: 1609559:TQ32_RS03190
uniprot id: A0A127B889
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1609559:TQ32 RS09125
gene id: 1609559:TQ32_RS09125
uniprot id: A0A127BB99
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1609559:TQ32 RS10440
gene id: 1609559:TQ32_RS10440
uniprot id: A0A127BC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS00960
gene id: 1609559:TQ32_RS00960
uniprot id: A0A127B749
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1609559:TQ32 RS08940
gene id: 1609559:TQ32_RS08940
uniprot id: A0A127BBL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homohexamer.

1609559:TQ32 RS03400
gene id: 1609559:TQ32_RS03400
uniprot id: A0A127B8L8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1609559:TQ32 RS07375
gene id: 1609559:TQ32_RS07375
uniprot id: A0A127BAF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1609559:TQ32 RS05725
gene id: 1609559:TQ32_RS05725
uniprot id: A0A127BCD5
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

1609559:TQ32 RS02380
gene id: 1609559:TQ32_RS02380
uniprot id: A0A127B9K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. MPGP family.
messages: Cytoplasm
messages: Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG).

1609559:TQ32 RS06960
gene id: 1609559:TQ32_RS06960
uniprot id: A0A127BAG9
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1609559:TQ32 RS01550
gene id: 1609559:TQ32_RS01550
uniprot id: A0A127B9K9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1609559:TQ32 RS03900
gene id: 1609559:TQ32_RS03900
uniprot id: A0A127B8M2
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1609559:TQ32 RS09580
gene id: 1609559:TQ32_RS09580
uniprot id: A0A127BBI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1609559:TQ32 RS01435
gene id: 1609559:TQ32_RS01435
uniprot id: A0A127B7S4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1609559:TQ32 RS06105
gene id: 1609559:TQ32_RS06105
uniprot id: A0A127B9Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1609559:TQ32 RS00805
gene id: 1609559:TQ32_RS00805
uniprot id: A0A127B743
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1609559:TQ32 RS04875
gene id: 1609559:TQ32_RS04875
uniprot id: A0A127B9A8
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1609559:TQ32 RS08675
gene id: 1609559:TQ32_RS08675
uniprot id: A0A127BCY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS10820
gene id: 1609559:TQ32_RS10820
uniprot id: A0A127BC46
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

1609559:TQ32 RS00300
gene id: 1609559:TQ32_RS00300
uniprot id: A0A127B794
names: Similarity
messages: Belongs to the glutaredoxin family.

1609559:TQ32 RS08620
gene id: 1609559:TQ32_RS08620
uniprot id: A0A127BCW6
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07970
gene id: 1609559:TQ32_RS07970
uniprot id: A0A127BAY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1609559:TQ32 RS03405
gene id: 1609559:TQ32_RS03405
uniprot id: A0A127B8Q4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1609559:TQ32 RS09065
gene id: 1609559:TQ32_RS09065
uniprot id: A0A127BCS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1609559:TQ32 RS03875
gene id: 1609559:TQ32_RS03875
uniprot id: A0A127B942
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1609559:TQ32 RS04250
gene id: 1609559:TQ32_RS04250
uniprot id: A0A127B924
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1609559:TQ32 RS05125
gene id: 1609559:TQ32_RS05125
uniprot id: A0A127BB97
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1609559:TQ32 RS00200
gene id: 1609559:TQ32_RS00200
uniprot id: A0A127B8Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1609559:TQ32 RS03450
gene id: 1609559:TQ32_RS03450
uniprot id: A0A127B8M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1609559:TQ32 RS09380
gene id: 1609559:TQ32_RS09380
uniprot id: A0A127BBU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

1609559:TQ32 RS08525
gene id: 1609559:TQ32_RS08525
uniprot id: A0A127BCI2
names: Similarity
messages: Belongs to the UPF0235 family.

1609559:TQ32 RS03745
gene id: 1609559:TQ32_RS03745
uniprot id: A0A127B8W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1609559:TQ32 RS08720
gene id: 1609559:TQ32_RS08720
uniprot id: A0A127BB44
names: Similarity
messages: Belongs to the enolase family.

1609559:TQ32 RS05960
gene id: 1609559:TQ32_RS05960
uniprot id: A0A127B9L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1609559:TQ32 RS09035
gene id: 1609559:TQ32_RS09035
uniprot id: A0A127BBA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1609559:TQ32 RS07940
gene id: 1609559:TQ32_RS07940
uniprot id: A0A127BAP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

1609559:TQ32 RS07390
gene id: 1609559:TQ32_RS07390
uniprot id: A0A127BAV5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1609559:TQ32 RS03910
gene id: 1609559:TQ32_RS03910
uniprot id: A0A127B8L2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1609559:TQ32 RS08305
gene id: 1609559:TQ32_RS08305
uniprot id: A0A127BAW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

1609559:TQ32 RS07775
gene id: 1609559:TQ32_RS07775
uniprot id: A0A127BAL0
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07560
gene id: 1609559:TQ32_RS07560
uniprot id: A0A127BAJ1
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1609559:TQ32 RS04950
gene id: 1609559:TQ32_RS04950
uniprot id: A0A127BB66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

1609559:TQ32 RS07090
gene id: 1609559:TQ32_RS07090
uniprot id: A0A127BA87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

1609559:TQ32 RS01110
gene id: 1609559:TQ32_RS01110
uniprot id: A0A127B7J3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1609559:TQ32 RS09205
gene id: 1609559:TQ32_RS09205
uniprot id: A0A127BBD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1609559:TQ32 RS09665
gene id: 1609559:TQ32_RS09665
uniprot id: A0A127BBL2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1609559:TQ32 RS07855
gene id: 1609559:TQ32_RS07855
uniprot id: A0A127BDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1609559:TQ32 RS10020
gene id: 1609559:TQ32_RS10020
uniprot id: A0A127BD97
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1609559:TQ32 RS04805
gene id: 1609559:TQ32_RS04805
uniprot id: A0A127B939
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1609559:TQ32 RS00460
gene id: 1609559:TQ32_RS00460
uniprot id: A0A127B791
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1609559:TQ32 RS08790
gene id: 1609559:TQ32_RS08790
uniprot id: A0A127BBD0
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS09030
gene id: 1609559:TQ32_RS09030
uniprot id: A0A127BB98
names: Similarity
messages: Belongs to the HypE family.

1609559:TQ32 RS07105
gene id: 1609559:TQ32_RS07105
uniprot id: A0A127BAA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

1609559:TQ32 RS08145
gene id: 1609559:TQ32_RS08145
uniprot id: A0A127BCB8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1609559:TQ32 RS00785
gene id: 1609559:TQ32_RS00785
uniprot id: A0A127B7F4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1609559:TQ32 RS02330
gene id: 1609559:TQ32_RS02330
uniprot id: A0A127B7U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1609559:TQ32 RS05315
gene id: 1609559:TQ32_RS05315
uniprot id: A0A127B9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1609559:TQ32 RS08970
gene id: 1609559:TQ32_RS08970
uniprot id: A0A127BCG3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1609559:TQ32 RS04350
gene id: 1609559:TQ32_RS04350
uniprot id: A0A127B9D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS08630
gene id: 1609559:TQ32_RS08630
uniprot id: A0A127BB16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbohydrate kinase PfkC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
messages: Cytoplasm

1609559:TQ32 RS06500
gene id: 1609559:TQ32_RS06500
uniprot id: A0A127B9Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1609559:TQ32 RS04480
gene id: 1609559:TQ32_RS04480
uniprot id: A0A127B8X9
names: Similarity
messages: Belongs to the peptidase U62 family.

1609559:TQ32 RS07945
gene id: 1609559:TQ32_RS07945
uniprot id: A0A127BAQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1609559:TQ32 RS01660
gene id: 1609559:TQ32_RS01660
uniprot id: A0A127B7V6
names: Caution
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1609559:TQ32 RS07695
gene id: 1609559:TQ32_RS07695
uniprot id: A0A127BAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS09490
gene id: 1609559:TQ32_RS09490
uniprot id: A0A127BDD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

1609559:TQ32 RS09610
gene id: 1609559:TQ32_RS09610
uniprot id: A0A127BCN6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1609559:TQ32 RS08610
gene id: 1609559:TQ32_RS08610
uniprot id: A0A127BB17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

1609559:TQ32 RS10355
gene id: 1609559:TQ32_RS10355
uniprot id: A0A127BBY9
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS06385
gene id: 1609559:TQ32_RS06385
uniprot id: A0A127B9Y7
names: Similarity
messages: Belongs to the archaeal ATPase family.

1609559:TQ32 RS10325
gene id: 1609559:TQ32_RS10325
uniprot id: A0A127BC41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

1609559:TQ32 RS06165
gene id: 1609559:TQ32_RS06165
uniprot id: A0A127B9S1
names: Similarity
messages: Belongs to the FUN14 family.

1609559:TQ32 RS05910
gene id: 1609559:TQ32_RS05910
uniprot id: A0A127BA31
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

1609559:TQ32 RS01500
gene id: 1609559:TQ32_RS01500
uniprot id: A0A127BC82
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1609559:TQ32 RS07550
gene id: 1609559:TQ32_RS07550
uniprot id: A0A127BAI7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1609559:TQ32 RS09480
gene id: 1609559:TQ32_RS09480
uniprot id: A0A127BCU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

1609559:TQ32 RS05550
gene id: 1609559:TQ32_RS05550
uniprot id: A0A127B9U6
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS01145
gene id: 1609559:TQ32_RS01145
uniprot id: A0A127B7L9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1609559:TQ32 RS10400
gene id: 1609559:TQ32_RS10400
uniprot id: A0A127BBX5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1609559:TQ32 RS03510
gene id: 1609559:TQ32_RS03510
uniprot id: A0A127BAF9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1609559:TQ32 RS10540
gene id: 1609559:TQ32_RS10540
uniprot id: A0A127BC13
names: Similarity
messages: Belongs to the GbsR family.

1609559:TQ32 RS09575
gene id: 1609559:TQ32_RS09575
uniprot id: A0A127BD12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

1609559:TQ32 RS04045
gene id: 1609559:TQ32_RS04045
uniprot id: A0A127B8X6
names: Similarity
messages: Belongs to the UPF0251 family.

1609559:TQ32 RS05615
gene id: 1609559:TQ32_RS05615
uniprot id: A0A127BB31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

1609559:TQ32 RS02410
gene id: 1609559:TQ32_RS02410
uniprot id: A0A127B852
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS08855
gene id: 1609559:TQ32_RS08855
uniprot id: A0A127BB57
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

1609559:TQ32 RS09185
gene id: 1609559:TQ32_RS09185
uniprot id: A0A127BCU5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1609559:TQ32 RS01440
gene id: 1609559:TQ32_RS01440
uniprot id: A0A127B7R2
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS08565
gene id: 1609559:TQ32_RS08565
uniprot id: A0A127BCV4
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1609559:TQ32 RS08350
gene id: 1609559:TQ32_RS08350
uniprot id: A0A127BAX9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1609559:TQ32 RS06510
gene id: 1609559:TQ32_RS06510
uniprot id: A0A127BCD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1609559:TQ32 RS04105
gene id: 1609559:TQ32_RS04105
uniprot id: A0A127B8R0
names: Similarity
messages: Belongs to the RutC family.

1609559:TQ32 RS01125
gene id: 1609559:TQ32_RS01125
uniprot id: A0A127B779
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS05850
gene id: 1609559:TQ32_RS05850
uniprot id: A0A127B9R4
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS05605
gene id: 1609559:TQ32_RS05605
uniprot id: A0A127B9U9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1609559:TQ32 RS09120
gene id: 1609559:TQ32_RS09120
uniprot id: A0A127BBA2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1609559:TQ32 RS09735
gene id: 1609559:TQ32_RS09735
uniprot id: A0A127BBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS05180
gene id: 1609559:TQ32_RS05180
uniprot id: A0A127B9N1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1609559:TQ32 RS09910
gene id: 1609559:TQ32_RS09910
uniprot id: A0A127BBP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS01685
gene id: 1609559:TQ32_RS01685
uniprot id: A0A127B7I4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

1609559:TQ32 RS00320
gene id: 1609559:TQ32_RS00320
uniprot id: A0A127B8J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1609559:TQ32 RS09650
gene id: 1609559:TQ32_RS09650
uniprot id: A0A127BBJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1609559:TQ32 RS09540
gene id: 1609559:TQ32_RS09540
uniprot id: A0A127BBI1
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS00770
gene id: 1609559:TQ32_RS00770
uniprot id: A0A127BE50
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

1609559:TQ32 RS05915
gene id: 1609559:TQ32_RS05915
uniprot id: A0A127BBM2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

1609559:TQ32 RS02745
gene id: 1609559:TQ32_RS02745
uniprot id: A0A127B815
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1609559:TQ32 RS02740
gene id: 1609559:TQ32_RS02740
uniprot id: A0A127B819
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1609559:TQ32 RS06425
gene id: 1609559:TQ32_RS06425
uniprot id: A0A127BA84
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1609559:TQ32 RS08905
gene id: 1609559:TQ32_RS08905
uniprot id: A0A127BB67
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1609559:TQ32 RS09485
gene id: 1609559:TQ32_RS09485
uniprot id: A0A127BBW1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1609559:TQ32 RS10045
gene id: 1609559:TQ32_RS10045
uniprot id: A0A127BBS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS07815
gene id: 1609559:TQ32_RS07815
uniprot id: A0A127BCF5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS04645
gene id: 1609559:TQ32_RS04645
uniprot id: A0A127B969
names: Similarity
messages: Belongs to the pyruvate kinase family.

1609559:TQ32 RS00615
gene id: 1609559:TQ32_RS00615
uniprot id: A0A127B705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1609559:TQ32 RS03345
gene id: 1609559:TQ32_RS03345
uniprot id: A0A127B8K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS09915
gene id: 1609559:TQ32_RS09915
uniprot id: A0A127BD74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS03580
gene id: 1609559:TQ32_RS03580
uniprot id: A0A127B8P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1609559:TQ32 RS09555
gene id: 1609559:TQ32_RS09555
uniprot id: A0A127BDE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS06355
gene id: 1609559:TQ32_RS06355
uniprot id: A0A127BBV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1609559:TQ32 RS00475
gene id: 1609559:TQ32_RS00475
uniprot id: A0A127B7H2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1609559:TQ32 RS07885
gene id: 1609559:TQ32_RS07885
uniprot id: A0A127BAN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

1609559:TQ32 RS09225
gene id: 1609559:TQ32_RS09225
uniprot id: A0A127BBK8
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

1609559:TQ32 RS05540
gene id: 1609559:TQ32_RS05540
uniprot id: A0A127B9V0
names: Similarity
messages: Belongs to the UPF0200 family.

1609559:TQ32 RS07650
gene id: 1609559:TQ32_RS07650
uniprot id: A0A127BAJ5
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1609559:TQ32 RS01590
gene id: 1609559:TQ32_RS01590
uniprot id: A0A127B7V2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1609559:TQ32 RS01905
gene id: 1609559:TQ32_RS01905
uniprot id: A0A127B7M0
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07640
gene id: 1609559:TQ32_RS07640
uniprot id: A0A127BC34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1609559:TQ32 RS07960
gene id: 1609559:TQ32_RS07960
uniprot id: A0A127BB50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS04890
gene id: 1609559:TQ32_RS04890
uniprot id: A0A127B9L4
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1609559:TQ32 RS09810
gene id: 1609559:TQ32_RS09810
uniprot id: A0A127BD53
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1609559:TQ32 RS06100
gene id: 1609559:TQ32_RS06100
uniprot id: A0A127B9S4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1609559:TQ32 RS00850
gene id: 1609559:TQ32_RS00850
uniprot id: A0A127B735
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1609559:TQ32 RS00945
gene id: 1609559:TQ32_RS00945
uniprot id: A0A127B7R4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1609559:TQ32 RS09365
gene id: 1609559:TQ32_RS09365
uniprot id: A0A127BBG0
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS06570
gene id: 1609559:TQ32_RS06570
uniprot id: A0A127BA04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS05905
gene id: 1609559:TQ32_RS05905
uniprot id: A0A127B9S3
names: Similarity
messages: Belongs to the HerA family.

1609559:TQ32 RS03045
gene id: 1609559:TQ32_RS03045
uniprot id: A0A127BA73
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

1609559:TQ32 RS10235
gene id: 1609559:TQ32_RS10235
uniprot id: A0A127BC86
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1609559:TQ32 RS03120
gene id: 1609559:TQ32_RS03120
uniprot id: A0A127B8R3
names: Similarity
messages: Belongs to the HypD family.

1609559:TQ32 RS07905
gene id: 1609559:TQ32_RS07905
uniprot id: A0A127BB40
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1609559:TQ32 RS06935
gene id: 1609559:TQ32_RS06935
uniprot id: A0A127BA68
names: Similarity
messages: Belongs to the AOR/FOR family.

1609559:TQ32 RS08990
gene id: 1609559:TQ32_RS08990
uniprot id: A0A127BB86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1609559:TQ32 RS10625
gene id: 1609559:TQ32_RS10625
uniprot id: A0A127BCE0
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS10345
gene id: 1609559:TQ32_RS10345
uniprot id: A0A127BBW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

1609559:TQ32 RS08890
gene id: 1609559:TQ32_RS08890
uniprot id: A0A127BBK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1609559:TQ32 RS08880
gene id: 1609559:TQ32_RS08880
uniprot id: A0A127BB70
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1609559:TQ32 RS10475
gene id: 1609559:TQ32_RS10475
uniprot id: A0A127BBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1609559:TQ32 RS07575
gene id: 1609559:TQ32_RS07575
uniprot id: A0A127BAS3
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

1609559:TQ32 RS06595
gene id: 1609559:TQ32_RS06595
uniprot id: A0A127BBZ6
names: Function
names: Similarity
messages: Belongs to the 2-phosphoglycerate kinase family.
messages: Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3-diphosphoglycerate. Involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant.

1609559:TQ32 RS03800
gene id: 1609559:TQ32_RS03800
uniprot id: A0A127B8T1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1609559:TQ32 RS02025
gene id: 1609559:TQ32_RS02025
uniprot id: A0A127B9D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP-dependent glucokinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.
messages: Cytoplasm

1609559:TQ32 RS07240
gene id: 1609559:TQ32_RS07240
uniprot id: A0A127BAC2
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1609559:TQ32 RS06795
gene id: 1609559:TQ32_RS06795
uniprot id: A0A127BBN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1609559:TQ32 RS03915
gene id: 1609559:TQ32_RS03915
uniprot id: A0A127B8U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1609559:TQ32 RS07920
gene id: 1609559:TQ32_RS07920
uniprot id: A0A127BAP0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1609559:TQ32 RS06205
gene id: 1609559:TQ32_RS06205
uniprot id: A0A127B9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS03280
gene id: 1609559:TQ32_RS03280
uniprot id: A0A127B8N8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1609559:TQ32 RS04400
gene id: 1609559:TQ32_RS04400
uniprot id: A0A127B985
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS10565
gene id: 1609559:TQ32_RS10565
uniprot id: A0A127BDZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS02975
gene id: 1609559:TQ32_RS02975
uniprot id: A0A127B844
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1609559:TQ32 RS10940
gene id: 1609559:TQ32_RS10940
uniprot id: A0A127BDP1
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1609559:TQ32 RS02910
gene id: 1609559:TQ32_RS02910
uniprot id: A0A127B829
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07570
gene id: 1609559:TQ32_RS07570
uniprot id: A0A127BCF8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1609559:TQ32 RS00395
gene id: 1609559:TQ32_RS00395
uniprot id: A0A127B6X2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1609559:TQ32 RS03430
gene id: 1609559:TQ32_RS03430
uniprot id: A0A127B8D8
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS03705
gene id: 1609559:TQ32_RS03705
uniprot id: A0A127B911
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS03730
gene id: 1609559:TQ32_RS03730
uniprot id: A0A127B8H1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS10610
gene id: 1609559:TQ32_RS10610
uniprot id: A0A127BC28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1609559:TQ32 RS07555
gene id: 1609559:TQ32_RS07555
uniprot id: A0A127BAJ4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1609559:TQ32 RS08965
gene id: 1609559:TQ32_RS08965
uniprot id: A0A127BB69
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1609559:TQ32 RS04090
gene id: 1609559:TQ32_RS04090
uniprot id: A0A127B978
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1609559:TQ32 RS07705
gene id: 1609559:TQ32_RS07705
uniprot id: A0A127BAK3
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS10080
gene id: 1609559:TQ32_RS10080
uniprot id: A0A127BBS0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1609559:TQ32 RS09590
gene id: 1609559:TQ32_RS09590
uniprot id: A0A127BBK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

1609559:TQ32 RS04355
gene id: 1609559:TQ32_RS04355
uniprot id: A0A127B941
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1609559:TQ32 RS07895
gene id: 1609559:TQ32_RS07895
uniprot id: A0A127BAQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1609559:TQ32 RS08530
gene id: 1609559:TQ32_RS08530
uniprot id: A0A127BAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1609559:TQ32 RS08615
gene id: 1609559:TQ32_RS08615
uniprot id: A0A127BBF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1609559:TQ32 RS04180
gene id: 1609559:TQ32_RS04180
uniprot id: A0A127B944
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

1609559:TQ32 RS00825
gene id: 1609559:TQ32_RS00825
uniprot id: A0A127B7H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS06370
gene id: 1609559:TQ32_RS06370
uniprot id: A0A127B9Y6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1609559:TQ32 RS07600
gene id: 1609559:TQ32_RS07600
uniprot id: A0A127BAI2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1609559:TQ32 RS10065
gene id: 1609559:TQ32_RS10065
uniprot id: A0A127BBS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS04145
gene id: 1609559:TQ32_RS04145
uniprot id: A0A127B904
names: Similarity
messages: Belongs to the carbamate kinase family.

1609559:TQ32 RS05715
gene id: 1609559:TQ32_RS05715
uniprot id: A0A127B9H6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

1609559:TQ32 RS05635
gene id: 1609559:TQ32_RS05635
uniprot id: A0A127B9H3
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1609559:TQ32 RS00700
gene id: 1609559:TQ32_RS00700
uniprot id: A0A127B7C4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

1609559:TQ32 RS07245
gene id: 1609559:TQ32_RS07245
uniprot id: A0A127BBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1609559:TQ32 RS09780
gene id: 1609559:TQ32_RS09780
uniprot id: A0A127BBN4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1609559:TQ32 RS04695
gene id: 1609559:TQ32_RS04695
uniprot id: A0A127B8Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

1609559:TQ32 RS08775
gene id: 1609559:TQ32_RS08775
uniprot id: A0A127BB46
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1609559:TQ32 RS03490
gene id: 1609559:TQ32_RS03490
uniprot id: A0A127B8E1
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1609559:TQ32 RS01870
gene id: 1609559:TQ32_RS01870
uniprot id: A0A127B7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1609559:TQ32 RS00100
gene id: 1609559:TQ32_RS00100
uniprot id: A0A127B798
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1609559:TQ32 RS07545
gene id: 1609559:TQ32_RS07545
uniprot id: A0A127BAH3
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS10485
gene id: 1609559:TQ32_RS10485
uniprot id: A0A127BCC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS06505
gene id: 1609559:TQ32_RS06505
uniprot id: A0A127BA03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1609559:TQ32 RS08750
gene id: 1609559:TQ32_RS08750
uniprot id: A0A127BCM3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1609559:TQ32 RS06835
gene id: 1609559:TQ32_RS06835
uniprot id: A0A127BAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1609559:TQ32 RS03895
gene id: 1609559:TQ32_RS03895
uniprot id: A0A127B8M3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-A/Apern subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1609559:TQ32 RS10650
gene id: 1609559:TQ32_RS10650
uniprot id: A0A127BC14
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07760
gene id: 1609559:TQ32_RS07760
uniprot id: A0A127BAL1
names: Similarity
messages: Belongs to the RuvB family.

1609559:TQ32 RS00075
gene id: 1609559:TQ32_RS00075
uniprot id: A0A127B6Q4
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

1609559:TQ32 RS07225
gene id: 1609559:TQ32_RS07225
uniprot id: A0A127BAR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1609559:TQ32 RS10900
gene id: 1609559:TQ32_RS10900
uniprot id: A0A127BC79
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1609559:TQ32 RS09760
gene id: 1609559:TQ32_RS09760
uniprot id: A0A127BD43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

1609559:TQ32 RS00760
gene id: 1609559:TQ32_RS00760
uniprot id: A0A127B7D4
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1609559:TQ32 RS03470
gene id: 1609559:TQ32_RS03470
uniprot id: A0A127B8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

1609559:TQ32 RS06950
gene id: 1609559:TQ32_RS06950
uniprot id: A0A127BA74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1609559:TQ32 RS03565
gene id: 1609559:TQ32_RS03565
uniprot id: A0A127B8T5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1609559:TQ32 RS03235
gene id: 1609559:TQ32_RS03235
uniprot id: A0A127BAA7
names: Similarity
messages: Belongs to the HypE family.

1609559:TQ32 RS02260
gene id: 1609559:TQ32_RS02260
uniprot id: A0A127B9J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS05825
gene id: 1609559:TQ32_RS05825
uniprot id: A0A127BB63
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS08435
gene id: 1609559:TQ32_RS08435
uniprot id: A0A127BCT6
names: Similarity
messages: Belongs to the class-I fumarase family.

1609559:TQ32 RS04720
gene id: 1609559:TQ32_RS04720
uniprot id: A0A127B9I3
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS10860
gene id: 1609559:TQ32_RS10860
uniprot id: A0A127BCI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1609559:TQ32 RS07385
gene id: 1609559:TQ32_RS07385
uniprot id: A0A127BAG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

1609559:TQ32 RS03810
gene id: 1609559:TQ32_RS03810
uniprot id: A0A127B8W9
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1609559:TQ32 RS09200
gene id: 1609559:TQ32_RS09200
uniprot id: A0A127BBC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS04960
gene id: 1609559:TQ32_RS04960
uniprot id: A0A127B9L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1609559:TQ32 RS07785
gene id: 1609559:TQ32_RS07785
uniprot id: A0A127BAN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1609559:TQ32 RS07985
gene id: 1609559:TQ32_RS07985
uniprot id: A0A127BAQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1609559:TQ32 RS08705
gene id: 1609559:TQ32_RS08705
uniprot id: A0A127BB20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1609559:TQ32 RS09005
gene id: 1609559:TQ32_RS09005
uniprot id: A0A127BBH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1609559:TQ32 RS06790
gene id: 1609559:TQ32_RS06790
uniprot id: A0A127BA51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

1609559:TQ32 RS00380
gene id: 1609559:TQ32_RS00380
uniprot id: A0A127B8K3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

1609559:TQ32 RS10660
gene id: 1609559:TQ32_RS10660
uniprot id: A0A127BC38
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS00185
gene id: 1609559:TQ32_RS00185
uniprot id: A0A127B6T6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS03310
gene id: 1609559:TQ32_RS03310
uniprot id: A0A127B8K4
names: Function
names: Similarity
messages: Belongs to the Tfx family.
messages: Putative transcriptional regulator.

1609559:TQ32 RS03530
gene id: 1609559:TQ32_RS03530
uniprot id: A0A127BA29
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

1609559:TQ32 RS07955
gene id: 1609559:TQ32_RS07955
uniprot id: A0A127BAR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1609559:TQ32 RS03180
gene id: 1609559:TQ32_RS03180
uniprot id: A0A127B8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

1609559:TQ32 RS03610
gene id: 1609559:TQ32_RS03610
uniprot id: A0A127B8F0
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS09925
gene id: 1609559:TQ32_RS09925
uniprot id: A0A127BBP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS08395
gene id: 1609559:TQ32_RS08395
uniprot id: A0A127BCG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

1609559:TQ32 RS03615
gene id: 1609559:TQ32_RS03615
uniprot id: A0A127B8G0
names: Subunit
messages: Homodimer.

1609559:TQ32 RS05515
gene id: 1609559:TQ32_RS05515
uniprot id: A0A127B9E7
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS01165
gene id: 1609559:TQ32_RS01165
uniprot id: A0A127B900
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

1609559:TQ32 RS10535
gene id: 1609559:TQ32_RS10535
uniprot id: A0A127BC18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS01265
gene id: 1609559:TQ32_RS01265
uniprot id: A0A127B9G0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1609559:TQ32 RS01825
gene id: 1609559:TQ32_RS01825
uniprot id: A0A127B7X6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1609559:TQ32 RS06985
gene id: 1609559:TQ32_RS06985
uniprot id: A0A127BA83
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS01065
gene id: 1609559:TQ32_RS01065
uniprot id: A0A127B761
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS02245
gene id: 1609559:TQ32_RS02245
uniprot id: A0A127B9U7
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1609559:TQ32 RS00250
gene id: 1609559:TQ32_RS00250
uniprot id: A0A127B788
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

1609559:TQ32 RS03495
gene id: 1609559:TQ32_RS03495
uniprot id: A0A127B8D5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

1609559:TQ32 RS09585
gene id: 1609559:TQ32_RS09585
uniprot id: A0A127BBI4
names: Similarity
messages: Belongs to the UPF0179 family.

1609559:TQ32 RS02405
gene id: 1609559:TQ32_RS02405
uniprot id: A0A127B7V3
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

1609559:TQ32 RS09940
gene id: 1609559:TQ32_RS09940
uniprot id: A0A127BBQ8
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS06075
gene id: 1609559:TQ32_RS06075
uniprot id: A0A127BBQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1609559:TQ32 RS06520
gene id: 1609559:TQ32_RS06520
uniprot id: A0A127B9Z2
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1609559:TQ32 RS00885
gene id: 1609559:TQ32_RS00885
uniprot id: A0A127B9A9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1609559:TQ32 RS08405
gene id: 1609559:TQ32_RS08405
uniprot id: A0A127BAX1
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS05830
gene id: 1609559:TQ32_RS05830
uniprot id: A0A127B9J8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS08055
gene id: 1609559:TQ32_RS08055
uniprot id: A0A127BAT6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1609559:TQ32 RS09775
gene id: 1609559:TQ32_RS09775
uniprot id: A0A127BBN0
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

1609559:TQ32 RS03440
gene id: 1609559:TQ32_RS03440
uniprot id: A0A127B8D2
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS05220
gene id: 1609559:TQ32_RS05220
uniprot id: A0A127B991
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS08680
gene id: 1609559:TQ32_RS08680
uniprot id: A0A127BBA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

1609559:TQ32 RS03940
gene id: 1609559:TQ32_RS03940
uniprot id: A0A127BA91
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1609559:TQ32 RS04665
gene id: 1609559:TQ32_RS04665
uniprot id: A0A127B992
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1609559:TQ32 RS09795
gene id: 1609559:TQ32_RS09795
uniprot id: A0A127BDJ8
names: Similarity
messages: Belongs to the FrhG family.

1609559:TQ32 RS02720
gene id: 1609559:TQ32_RS02720
uniprot id: A0A127B9R7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1609559:TQ32 RS06180
gene id: 1609559:TQ32_RS06180
uniprot id: A0A127BA92
names: Similarity
messages: Belongs to the UPF0127 family.

1609559:TQ32 RS10810
gene id: 1609559:TQ32_RS10810
uniprot id: A0A127BC49
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

1609559:TQ32 RS06980
gene id: 1609559:TQ32_RS06980
uniprot id: A0A127BA76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS08355
gene id: 1609559:TQ32_RS08355
uniprot id: A0A127BAY6
names: Similarity
messages: Belongs to the thymidylate kinase family.

1609559:TQ32 RS03320
gene id: 1609559:TQ32_RS03320
uniprot id: A0A127BCA2
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1609559:TQ32 RS09690
gene id: 1609559:TQ32_RS09690
uniprot id: A0A127BDG3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1609559:TQ32 RS07350
gene id: 1609559:TQ32_RS07350
uniprot id: A0A127BAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1609559:TQ32 RS10645
gene id: 1609559:TQ32_RS10645
uniprot id: A0A127BDJ4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1609559:TQ32 RS09870
gene id: 1609559:TQ32_RS09870
uniprot id: A0A127BBN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS04590
gene id: 1609559:TQ32_RS04590
uniprot id: A0A127B8Y2
names: Similarity
messages: Belongs to the MoaD family.

1609559:TQ32 RS06315
gene id: 1609559:TQ32_RS06315
uniprot id: A0A127BBF5
names: Similarity
messages: Belongs to the serpin family.

1609559:TQ32 RS10305
gene id: 1609559:TQ32_RS10305
uniprot id: A0A127BBX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS06535
gene id: 1609559:TQ32_RS06535
uniprot id: A0A127BBY7
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.

1609559:TQ32 RS08810
gene id: 1609559:TQ32_RS08810
uniprot id: A0A127BCM8
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1609559:TQ32 RS01560
gene id: 1609559:TQ32_RS01560
uniprot id: A0A127B7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1609559:TQ32 RS06155
gene id: 1609559:TQ32_RS06155
uniprot id: A0A127B9R6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1609559:TQ32 RS08700
gene id: 1609559:TQ32_RS08700
uniprot id: A0A127BB21
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1609559:TQ32 RS00880
gene id: 1609559:TQ32_RS00880
uniprot id: A0A127B7H8
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS02100
gene id: 1609559:TQ32_RS02100
uniprot id: A0A127B7Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1609559:TQ32 RS00440
gene id: 1609559:TQ32_RS00440
uniprot id: A0A127B6W9
names: Similarity
messages: Belongs to the UPF0146 family.

1609559:TQ32 RS00005
gene id: 1609559:TQ32_RS00005
uniprot id: A0A127BC67
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS06055
gene id: 1609559:TQ32_RS06055
uniprot id: A0A127B9P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1609559:TQ32 RS05890
gene id: 1609559:TQ32_RS05890
uniprot id: A0A127B9M4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1609559:TQ32 RS02455
gene id: 1609559:TQ32_RS02455
uniprot id: A0A127B7X7
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS01055
gene id: 1609559:TQ32_RS01055
uniprot id: A0A127B7I6
names: Similarity
messages: Belongs to the archaeal ATPase family.

1609559:TQ32 RS01095
gene id: 1609559:TQ32_RS01095
uniprot id: A0A127B7K6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

1609559:TQ32 RS09210
gene id: 1609559:TQ32_RS09210
uniprot id: A0A127BBC1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1609559:TQ32 RS00605
gene id: 1609559:TQ32_RS00605
uniprot id: A0A127B8P6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1609559:TQ32 RS07230
gene id: 1609559:TQ32_RS07230
uniprot id: A0A127BC97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1609559:TQ32 RS03005
gene id: 1609559:TQ32_RS03005
uniprot id: A0A127B9U4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1609559:TQ32 RS10095
gene id: 1609559:TQ32_RS10095
uniprot id: A0A127BBT1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

1609559:TQ32 RS00530
gene id: 1609559:TQ32_RS00530
uniprot id: A0A127B7C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

1609559:TQ32 RS09720
gene id: 1609559:TQ32_RS09720
uniprot id: A0A127BBM0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1609559:TQ32 RS00680
gene id: 1609559:TQ32_RS00680
uniprot id: A0A127B723
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1609559:TQ32 RS06710
gene id: 1609559:TQ32_RS06710
uniprot id: A0A127BAD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1609559:TQ32 RS04080
gene id: 1609559:TQ32_RS04080
uniprot id: A0A127B923
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1609559:TQ32 RS08690
gene id: 1609559:TQ32_RS08690
uniprot id: A0A127BB27
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1609559:TQ32 RS01370
gene id: 1609559:TQ32_RS01370
uniprot id: A0A127B7Q7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1609559:TQ32 RS09360
gene id: 1609559:TQ32_RS09360
uniprot id: A0A127BBE3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1609559:TQ32 RS05620
gene id: 1609559:TQ32_RS05620
uniprot id: A0A127B9G6
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07995
gene id: 1609559:TQ32_RS07995
uniprot id: A0A127BAR7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1609559:TQ32 RS07495
gene id: 1609559:TQ32_RS07495
uniprot id: A0A127BAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1609559:TQ32 RS01185
gene id: 1609559:TQ32_RS01185
uniprot id: A0A127B799
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1609559:TQ32 RS04985
gene id: 1609559:TQ32_RS04985
uniprot id: A0A127B947
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS08050
gene id: 1609559:TQ32_RS08050
uniprot id: A0A127BAS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1609559:TQ32 RS01680
gene id: 1609559:TQ32_RS01680
uniprot id: A0A127B988
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

1609559:TQ32 RS08985
gene id: 1609559:TQ32_RS08985
uniprot id: A0A127BB92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

1609559:TQ32 RS00315
gene id: 1609559:TQ32_RS00315
uniprot id: A0A127B771
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

1609559:TQ32 RS09855
gene id: 1609559:TQ32_RS09855
uniprot id: A0A127BBW0
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS00705
gene id: 1609559:TQ32_RS00705
uniprot id: A0A127B7F5
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07915
gene id: 1609559:TQ32_RS07915
uniprot id: A0A127BAY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS04895
gene id: 1609559:TQ32_RS04895
uniprot id: A0A127B9B9
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1609559:TQ32 RS02425
gene id: 1609559:TQ32_RS02425
uniprot id: A0A127B8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1609559:TQ32 RS09165
gene id: 1609559:TQ32_RS09165
uniprot id: A0A127BCH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1609559:TQ32 RS05535
gene id: 1609559:TQ32_RS05535
uniprot id: A0A127B9L9
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

1609559:TQ32 RS05025
gene id: 1609559:TQ32_RS05025
uniprot id: A0A127BAT4
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07900
gene id: 1609559:TQ32_RS07900
uniprot id: A0A127BAQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1609559:TQ32 RS08425
gene id: 1609559:TQ32_RS08425
uniprot id: A0A127BAY7
names: Similarity
messages: Belongs to the UPF0175 family.

1609559:TQ32 RS09175
gene id: 1609559:TQ32_RS09175
uniprot id: A0A127BBJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1609559:TQ32 RS06750
gene id: 1609559:TQ32_RS06750
uniprot id: A0A127BA50
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1609559:TQ32 RS10435
gene id: 1609559:TQ32_RS10435
uniprot id: A0A127BDX1
names: Subcellular Location Annotation
messages: Membrane

1609559:TQ32 RS07710
gene id: 1609559:TQ32_RS07710
uniprot id: A0A127BAK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

1609559:TQ32 RS03115
gene id: 1609559:TQ32_RS03115
uniprot id: A0A127BA88
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.