1604335:DXZ79 RS03300
gene id: 1604335:DXZ79_RS03300
uniprot id: A0A386HBD2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS14595
gene id: 1604335:DXZ79_RS14595
uniprot id: A0A386HG49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1604335:DXZ79 RS20075
gene id: 1604335:DXZ79_RS20075
uniprot id: A0A386HJG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS09495
gene id: 1604335:DXZ79_RS09495
uniprot id: A0A386HDL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS06795
gene id: 1604335:DXZ79_RS06795
uniprot id: A0A386HCU5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1604335:DXZ79 RS07840
gene id: 1604335:DXZ79_RS07840
uniprot id: A0A386HDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1604335:DXZ79 RS01190
gene id: 1604335:DXZ79_RS01190
uniprot id: A0A386HA69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1604335:DXZ79 RS06740
gene id: 1604335:DXZ79_RS06740
uniprot id: A0A386HCZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

1604335:DXZ79 RS05765
gene id: 1604335:DXZ79_RS05765
uniprot id: A0A386HC20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

1604335:DXZ79 RS15760
gene id: 1604335:DXZ79_RS15760
uniprot id: A0A386HHG1
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1604335:DXZ79 RS12670
gene id: 1604335:DXZ79_RS12670
uniprot id: A0A386HFT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1604335:DXZ79 RS16420
gene id: 1604335:DXZ79_RS16420
uniprot id: A0A386HH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS15545
gene id: 1604335:DXZ79_RS15545
uniprot id: A0A386HHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1604335:DXZ79 RS19010
gene id: 1604335:DXZ79_RS19010
uniprot id: A0A386HIQ2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1604335:DXZ79 RS17970
gene id: 1604335:DXZ79_RS17970
uniprot id: A0A386HHQ2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1604335:DXZ79 RS03915
gene id: 1604335:DXZ79_RS03915
uniprot id: A0A386HB85
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS16130
gene id: 1604335:DXZ79_RS16130
uniprot id: A0A386HHJ6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1604335:DXZ79 RS10430
gene id: 1604335:DXZ79_RS10430
uniprot id: A0A386HEQ5
names: Similarity
messages: Belongs to the UPF0482 family.

1604335:DXZ79 RS07025
gene id: 1604335:DXZ79_RS07025
uniprot id: A0A386HCE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1604335:DXZ79 RS18525
gene id: 1604335:DXZ79_RS18525
uniprot id: A0A386HJ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS19500
gene id: 1604335:DXZ79_RS19500
uniprot id: A0A386HJC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1604335:DXZ79 RS09035
gene id: 1604335:DXZ79_RS09035
uniprot id: A0A8D4SS21
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS01600
gene id: 1604335:DXZ79_RS01600
uniprot id: A0A386H9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

1604335:DXZ79 RS07905
gene id: 1604335:DXZ79_RS07905
uniprot id: A0A386HDN6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1604335:DXZ79 RS08550
gene id: 1604335:DXZ79_RS08550
uniprot id: A0A386HD98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS03735
gene id: 1604335:DXZ79_RS03735
uniprot id: A0A386HBB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1604335:DXZ79 RS07960
gene id: 1604335:DXZ79_RS07960
uniprot id: A0A386HD02
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1604335:DXZ79 RS05400
gene id: 1604335:DXZ79_RS05400
uniprot id: A0A386HC50
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

1604335:DXZ79 RS18910
gene id: 1604335:DXZ79_RS18910
uniprot id: A0A386HIN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1604335:DXZ79 RS01180
gene id: 1604335:DXZ79_RS01180
uniprot id: A0A386HA76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

1604335:DXZ79 RS18715
gene id: 1604335:DXZ79_RS18715
uniprot id: A0A386HIT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1604335:DXZ79 RS00950
gene id: 1604335:DXZ79_RS00950
uniprot id: A0A386HA93
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1604335:DXZ79 RS12590
gene id: 1604335:DXZ79_RS12590
uniprot id: A0A386HF72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1604335:DXZ79 RS09550
gene id: 1604335:DXZ79_RS09550
uniprot id: A0A386HDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

1604335:DXZ79 RS09770
gene id: 1604335:DXZ79_RS09770
uniprot id: A0A386HDR4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1604335:DXZ79 RS10955
gene id: 1604335:DXZ79_RS10955
uniprot id: A0A386HEE8
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11725
gene id: 1604335:DXZ79_RS11725
uniprot id: A0A386HFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1604335:DXZ79 RS19300
gene id: 1604335:DXZ79_RS19300
uniprot id: A0A386HJ41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS18135
gene id: 1604335:DXZ79_RS18135
uniprot id: A0A386HHS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1604335:DXZ79 RS18365
gene id: 1604335:DXZ79_RS18365
uniprot id: A0A8D4ST91
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS19225
gene id: 1604335:DXZ79_RS19225
uniprot id: A0A386HIX1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1604335:DXZ79 RS17350
gene id: 1604335:DXZ79_RS17350
uniprot id: A0A386HHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1604335:DXZ79 RS17015
gene id: 1604335:DXZ79_RS17015
uniprot id: A0A386HHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1604335:DXZ79 RS11485
gene id: 1604335:DXZ79_RS11485
uniprot id: A0A386HFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS02360
gene id: 1604335:DXZ79_RS02360
uniprot id: A0A386HA39
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

1604335:DXZ79 RS10620
gene id: 1604335:DXZ79_RS10620
uniprot id: A0A386HE40
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1604335:DXZ79 RS08825
gene id: 1604335:DXZ79_RS08825
uniprot id: A0A386HDF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS19425
gene id: 1604335:DXZ79_RS19425
uniprot id: A0A386HJ62
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

1604335:DXZ79 RS20210
gene id: 1604335:DXZ79_RS20210
uniprot id: A0A386HJN4
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

1604335:DXZ79 RS15800
gene id: 1604335:DXZ79_RS15800
uniprot id: A0A8D4N1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1604335:DXZ79 RS17910
gene id: 1604335:DXZ79_RS17910
uniprot id: A0A386HHP5
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS18975
gene id: 1604335:DXZ79_RS18975
uniprot id: A0A386HI62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1604335:DXZ79 RS19025
gene id: 1604335:DXZ79_RS19025
uniprot id: A0A386HI73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1604335:DXZ79 RS07660
gene id: 1604335:DXZ79_RS07660
uniprot id: A0A386HCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1604335:DXZ79 RS07335
gene id: 1604335:DXZ79_RS07335
uniprot id: A0A386HD76
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1604335:DXZ79 RS03320
gene id: 1604335:DXZ79_RS03320
uniprot id: A0A386HAJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS07795
gene id: 1604335:DXZ79_RS07795
uniprot id: A0A386HDM0
names: Similarity
messages: Belongs to the EutP/PduV family.

1604335:DXZ79 RS09310
gene id: 1604335:DXZ79_RS09310
uniprot id: A0A386HEG9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1604335:DXZ79 RS02500
gene id: 1604335:DXZ79_RS02500
uniprot id: A0A386HAQ6
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1604335:DXZ79 RS19555
gene id: 1604335:DXZ79_RS19555
uniprot id: A0A386HJH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS15155
gene id: 1604335:DXZ79_RS15155
uniprot id: A0A386HGF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1604335:DXZ79 RS18835
gene id: 1604335:DXZ79_RS18835
uniprot id: A0A386HIQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1604335:DXZ79 RS04345
gene id: 1604335:DXZ79_RS04345
uniprot id: A0A386HBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1604335:DXZ79 RS02300
gene id: 1604335:DXZ79_RS02300
uniprot id: A0A8D4N1G4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1604335:DXZ79 RS19050
gene id: 1604335:DXZ79_RS19050
uniprot id: A0A386HIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1604335:DXZ79 RS02270
gene id: 1604335:DXZ79_RS02270
uniprot id: A0A386HAY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1604335:DXZ79 RS19260
gene id: 1604335:DXZ79_RS19260
uniprot id: A0A386HIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1604335:DXZ79 RS00365
gene id: 1604335:DXZ79_RS00365
uniprot id: A0A386H9I9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1604335:DXZ79 RS04625
gene id: 1604335:DXZ79_RS04625
uniprot id: A0A386HBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1604335:DXZ79 RS16260
gene id: 1604335:DXZ79_RS16260
uniprot id: A0A386HHP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1604335:DXZ79 RS16305
gene id: 1604335:DXZ79_RS16305
uniprot id: A0A386HGZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1604335:DXZ79 RS01460
gene id: 1604335:DXZ79_RS01460
uniprot id: A0A386H9N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1604335:DXZ79 RS12450
gene id: 1604335:DXZ79_RS12450
uniprot id: A0A386HF36
names: Similarity
messages: Belongs to the acylphosphatase family.

1604335:DXZ79 RS16410
gene id: 1604335:DXZ79_RS16410
uniprot id: A0A386HHI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

1604335:DXZ79 RS19415
gene id: 1604335:DXZ79_RS19415
uniprot id: A0A386HJS5
names: Similarity
messages: Belongs to the FeoA family.

1604335:DXZ79 RS04880
gene id: 1604335:DXZ79_RS04880
uniprot id: A0A386HBC6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1604335:DXZ79 RS13535
gene id: 1604335:DXZ79_RS13535
uniprot id: A0A386HGI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

1604335:DXZ79 RS03870
gene id: 1604335:DXZ79_RS03870
uniprot id: A0A386HAW0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

1604335:DXZ79 RS16810
gene id: 1604335:DXZ79_RS16810
uniprot id: A0A386HH70
names: Similarity
messages: Belongs to the peptidase A31 family.

1604335:DXZ79 RS07800
gene id: 1604335:DXZ79_RS07800
uniprot id: A0A386HCX2
names: Subcellular Location Annotation
messages: Bacterial microcompartment

1604335:DXZ79 RS05270
gene id: 1604335:DXZ79_RS05270
uniprot id: A0A8E4BMJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1604335:DXZ79 RS15565
gene id: 1604335:DXZ79_RS15565
uniprot id: A0A386HHV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1604335:DXZ79 RS00875
gene id: 1604335:DXZ79_RS00875
uniprot id: A0A386H9E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1604335:DXZ79 RS12720
gene id: 1604335:DXZ79_RS12720
uniprot id: A0A386HFU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS05855
gene id: 1604335:DXZ79_RS05855
uniprot id: A0A386HCJ9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1604335:DXZ79 RS20430
gene id: 1604335:DXZ79_RS20430
uniprot id: A0A386HJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS07750
gene id: 1604335:DXZ79_RS07750
uniprot id: A0A386HDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS01720
gene id: 1604335:DXZ79_RS01720
uniprot id: A0A8D4N1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1604335:DXZ79 RS15470
gene id: 1604335:DXZ79_RS15470
uniprot id: A0A386HH71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS10300
gene id: 1604335:DXZ79_RS10300
uniprot id: A0A386HER6
names: Similarity
messages: Belongs to the ribulokinase family.

1604335:DXZ79 RS17170
gene id: 1604335:DXZ79_RS17170
uniprot id: A0A8E4DFH6
names: Similarity
messages: Belongs to the peptidase A24 family.

1604335:DXZ79 RS17925
gene id: 1604335:DXZ79_RS17925
uniprot id: A0A386HII7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1604335:DXZ79 RS08595
gene id: 1604335:DXZ79_RS08595
uniprot id: A0A386HDY5
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1604335:DXZ79 RS04195
gene id: 1604335:DXZ79_RS04195
uniprot id: A0A386HBD0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1604335:DXZ79 RS00440
gene id: 1604335:DXZ79_RS00440
uniprot id: A0A386HA17
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1604335:DXZ79 RS05065
gene id: 1604335:DXZ79_RS05065
uniprot id: A0A386HBP4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1604335:DXZ79 RS06605
gene id: 1604335:DXZ79_RS06605
uniprot id: A0A386HCZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1604335:DXZ79 RS03935
gene id: 1604335:DXZ79_RS03935
uniprot id: A0A8D4SM40
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS05705
gene id: 1604335:DXZ79_RS05705
uniprot id: A0A386HC77
names: Similarity
messages: Belongs to the ArsC family.

1604335:DXZ79 RS17280
gene id: 1604335:DXZ79_RS17280
uniprot id: A0A386HHX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1604335:DXZ79 RS19295
gene id: 1604335:DXZ79_RS19295
uniprot id: A0A386HIU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1604335:DXZ79 RS09855
gene id: 1604335:DXZ79_RS09855
uniprot id: A0A386HEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1604335:DXZ79 RS13245
gene id: 1604335:DXZ79_RS13245
uniprot id: A0A8D4N455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1604335:DXZ79 RS06200
gene id: 1604335:DXZ79_RS06200
uniprot id: A0A386HCH3
names: Similarity
messages: Belongs to the Rht family.

1604335:DXZ79 RS04995
gene id: 1604335:DXZ79_RS04995
uniprot id: A0A386HC43
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1604335:DXZ79 RS12585
gene id: 1604335:DXZ79_RS12585
uniprot id: A0A386HG05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

1604335:DXZ79 RS16950
gene id: 1604335:DXZ79_RS16950
uniprot id: A0A8D4SPA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1604335:DXZ79 RS18670
gene id: 1604335:DXZ79_RS18670
uniprot id: A0A386HIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

1604335:DXZ79 RS09455
gene id: 1604335:DXZ79_RS09455
uniprot id: A0A386HE64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS15830
gene id: 1604335:DXZ79_RS15830
uniprot id: A0A386HI07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
messages: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS11735
gene id: 1604335:DXZ79_RS11735
uniprot id: A0A386HER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1604335:DXZ79 RS03430
gene id: 1604335:DXZ79_RS03430
uniprot id: A0A386HAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

1604335:DXZ79 RS09475
gene id: 1604335:DXZ79_RS09475
uniprot id: A0A8D4MZD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1604335:DXZ79 RS11560
gene id: 1604335:DXZ79_RS11560
uniprot id: A0A386HEJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

1604335:DXZ79 RS01610
gene id: 1604335:DXZ79_RS01610
uniprot id: A0A386HAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

1604335:DXZ79 RS09850
gene id: 1604335:DXZ79_RS09850
uniprot id: A0A386HEE1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1604335:DXZ79 RS05075
gene id: 1604335:DXZ79_RS05075
uniprot id: A0A386HC72
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1604335:DXZ79 RS10740
gene id: 1604335:DXZ79_RS10740
uniprot id: A0A386HF06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1604335:DXZ79 RS05275
gene id: 1604335:DXZ79_RS05275
uniprot id: A0A386HBN1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1604335:DXZ79 RS04835
gene id: 1604335:DXZ79_RS04835
uniprot id: A0A386HBV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1604335:DXZ79 RS16275
gene id: 1604335:DXZ79_RS16275
uniprot id: A0A386HHF3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1604335:DXZ79 RS16265
gene id: 1604335:DXZ79_RS16265
uniprot id: A0A386HHV5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1604335:DXZ79 RS15475
gene id: 1604335:DXZ79_RS15475
uniprot id: A0A386HGJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1604335:DXZ79 RS15460
gene id: 1604335:DXZ79_RS15460
uniprot id: A0A386HHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1604335:DXZ79 RS09350
gene id: 1604335:DXZ79_RS09350
uniprot id: A0A386HE99
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1604335:DXZ79 RS19360
gene id: 1604335:DXZ79_RS19360
uniprot id: A0A386HJR6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1604335:DXZ79 RS04810
gene id: 1604335:DXZ79_RS04810
uniprot id: A0A386HBU1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS00410
gene id: 1604335:DXZ79_RS00410
uniprot id: A0A386H9S5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1604335:DXZ79 RS17340
gene id: 1604335:DXZ79_RS17340
uniprot id: A0A8D4N6W1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1604335:DXZ79 RS17565
gene id: 1604335:DXZ79_RS17565
uniprot id: A0A386HHJ2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1604335:DXZ79 RS08600
gene id: 1604335:DXZ79_RS08600
uniprot id: A0A386HDA8
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1604335:DXZ79 RS12955
gene id: 1604335:DXZ79_RS12955
uniprot id: A0A386HFS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1604335:DXZ79 RS14015
gene id: 1604335:DXZ79_RS14015
uniprot id: A0A386HFT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

1604335:DXZ79 RS15235
gene id: 1604335:DXZ79_RS15235
uniprot id: A0A386HGE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1604335:DXZ79 RS00820
gene id: 1604335:DXZ79_RS00820
uniprot id: A0A386H9G0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS18325
gene id: 1604335:DXZ79_RS18325
uniprot id: A0A8D4N780
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS04735
gene id: 1604335:DXZ79_RS04735
uniprot id: A0A8D4MZX4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1604335:DXZ79 RS07310
gene id: 1604335:DXZ79_RS07310
uniprot id: A0A386HDC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS00960
gene id: 1604335:DXZ79_RS00960
uniprot id: A0A386HA36
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

1604335:DXZ79 RS12280
gene id: 1604335:DXZ79_RS12280
uniprot id: A0A386HF12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1604335:DXZ79 RS00170
gene id: 1604335:DXZ79_RS00170
uniprot id: A0A386H9R8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1604335:DXZ79 RS05830
gene id: 1604335:DXZ79_RS05830
uniprot id: A0A386HC74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1604335:DXZ79 RS18205
gene id: 1604335:DXZ79_RS18205
uniprot id: A0A386HI68
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1604335:DXZ79 RS15105
gene id: 1604335:DXZ79_RS15105
uniprot id: A0A386HGE0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1604335:DXZ79 RS15695
gene id: 1604335:DXZ79_RS15695
uniprot id: A0A386HHF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS01400
gene id: 1604335:DXZ79_RS01400
uniprot id: A0A386HA51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1604335:DXZ79 RS01225
gene id: 1604335:DXZ79_RS01225
uniprot id: A0A386HA56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1604335:DXZ79 RS15310
gene id: 1604335:DXZ79_RS15310
uniprot id: A0A8D4N5R4
names: Similarity
messages: Belongs to the YkuD family.

1604335:DXZ79 RS18945
gene id: 1604335:DXZ79_RS18945
uniprot id: A0A386HIS1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1604335:DXZ79 RS13720
gene id: 1604335:DXZ79_RS13720
uniprot id: A0A386HG45
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS15620
gene id: 1604335:DXZ79_RS15620
uniprot id: A0A386HH49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1604335:DXZ79 RS00895
gene id: 1604335:DXZ79_RS00895
uniprot id: A0A386H9Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1604335:DXZ79 RS19760
gene id: 1604335:DXZ79_RS19760
uniprot id: A0A386HJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1604335:DXZ79 RS18380
gene id: 1604335:DXZ79_RS18380
uniprot id: A0A8D4N5S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1604335:DXZ79 RS08635
gene id: 1604335:DXZ79_RS08635
uniprot id: A0A386HDV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1604335:DXZ79 RS06110
gene id: 1604335:DXZ79_RS06110
uniprot id: A0A386HCP2
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS02705
gene id: 1604335:DXZ79_RS02705
uniprot id: A0A386HB20
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1604335:DXZ79 RS06545
gene id: 1604335:DXZ79_RS06545
uniprot id: A0A8D4N200
names: Similarity
messages: Belongs to the asparagine synthetase family.

1604335:DXZ79 RS12795
gene id: 1604335:DXZ79_RS12795
uniprot id: A0A386HGI3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS06765
gene id: 1604335:DXZ79_RS06765
uniprot id: A0A386HD24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1604335:DXZ79 RS05970
gene id: 1604335:DXZ79_RS05970
uniprot id: A0A8D4SR80
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS12495
gene id: 1604335:DXZ79_RS12495
uniprot id: A0A386HFE5
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS04725
gene id: 1604335:DXZ79_RS04725
uniprot id: A0A8D4SQ07
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1604335:DXZ79 RS07030
gene id: 1604335:DXZ79_RS07030
uniprot id: A0A386HCD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1604335:DXZ79 RS03885
gene id: 1604335:DXZ79_RS03885
uniprot id: A0A386HBJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1604335:DXZ79 RS03185
gene id: 1604335:DXZ79_RS03185
uniprot id: A0A386HAH1
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS03950
gene id: 1604335:DXZ79_RS03950
uniprot id: A0A386HB40
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1604335:DXZ79 RS12235
gene id: 1604335:DXZ79_RS12235
uniprot id: A0A386HFK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1604335:DXZ79 RS07170
gene id: 1604335:DXZ79_RS07170
uniprot id: A0A386HCV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1604335:DXZ79 RS09450
gene id: 1604335:DXZ79_RS09450
uniprot id: A0A386HDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1604335:DXZ79 RS01670
gene id: 1604335:DXZ79_RS01670
uniprot id: A0A8D4SP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1604335:DXZ79 RS08560
gene id: 1604335:DXZ79_RS08560
uniprot id: A0A386HE22
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1604335:DXZ79 RS12645
gene id: 1604335:DXZ79_RS12645
uniprot id: A0A386HGE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

1604335:DXZ79 RS17395
gene id: 1604335:DXZ79_RS17395
uniprot id: A0A386HHZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

1604335:DXZ79 RS08850
gene id: 1604335:DXZ79_RS08850
uniprot id: A0A386HDB1
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

1604335:DXZ79 RS17955
gene id: 1604335:DXZ79_RS17955
uniprot id: A0A386HI99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

1604335:DXZ79 RS08605
gene id: 1604335:DXZ79_RS08605
uniprot id: A0A386HDJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1604335:DXZ79 RS02700
gene id: 1604335:DXZ79_RS02700
uniprot id: A0A386HA99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS04765
gene id: 1604335:DXZ79_RS04765
uniprot id: A0A386HBT3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1604335:DXZ79 RS07785
gene id: 1604335:DXZ79_RS07785
uniprot id: A0A386HDF0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1604335:DXZ79 RS10545
gene id: 1604335:DXZ79_RS10545
uniprot id: A0A386HEE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1604335:DXZ79 RS13375
gene id: 1604335:DXZ79_RS13375
uniprot id: A0A8D4N6D0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.

1604335:DXZ79 RS11145
gene id: 1604335:DXZ79_RS11145
uniprot id: A0A386HF18
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1604335:DXZ79 RS11855
gene id: 1604335:DXZ79_RS11855
uniprot id: A0A386HFL6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1604335:DXZ79 RS15225
gene id: 1604335:DXZ79_RS15225
uniprot id: A0A386HGX7
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS18920
gene id: 1604335:DXZ79_RS18920
uniprot id: A0A386HI64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1604335:DXZ79 RS07050
gene id: 1604335:DXZ79_RS07050
uniprot id: A0A386HJZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1604335:DXZ79 RS17935
gene id: 1604335:DXZ79_RS17935
uniprot id: A0A386HI14
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1604335:DXZ79 RS11585
gene id: 1604335:DXZ79_RS11585
uniprot id: A0A386HER2
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS19075
gene id: 1604335:DXZ79_RS19075
uniprot id: A0A386HI96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

1604335:DXZ79 RS11055
gene id: 1604335:DXZ79_RS11055
uniprot id: A0A386HEN1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

1604335:DXZ79 RS01380
gene id: 1604335:DXZ79_RS01380
uniprot id: A0A8D4MX13
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1604335:DXZ79 RS18570
gene id: 1604335:DXZ79_RS18570
uniprot id: A0A386HIQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1604335:DXZ79 RS08290
gene id: 1604335:DXZ79_RS08290
uniprot id: A0A386HD09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

1604335:DXZ79 RS08260
gene id: 1604335:DXZ79_RS08260
uniprot id: A0A386HD46
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS16680
gene id: 1604335:DXZ79_RS16680
uniprot id: A0A386HHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1604335:DXZ79 RS09940
gene id: 1604335:DXZ79_RS09940
uniprot id: A0A386HDU2
names: Similarity
messages: Belongs to the YciI family.

1604335:DXZ79 RS12310
gene id: 1604335:DXZ79_RS12310
uniprot id: A0A386HG78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1604335:DXZ79 RS15140
gene id: 1604335:DXZ79_RS15140
uniprot id: A0A386HH01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1604335:DXZ79 RS06940
gene id: 1604335:DXZ79_RS06940
uniprot id: A0A386HCV5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1604335:DXZ79 RS06955
gene id: 1604335:DXZ79_RS06955
uniprot id: A0A386HCR5
names: Similarity
messages: Belongs to the aldose epimerase family.

1604335:DXZ79 RS02695
gene id: 1604335:DXZ79_RS02695
uniprot id: A0A8E4BMD1
names: Similarity
messages: Belongs to the UPF0213 family.

1604335:DXZ79 RS12135
gene id: 1604335:DXZ79_RS12135
uniprot id: A0A386HFL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoB family.
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

1604335:DXZ79 RS11135
gene id: 1604335:DXZ79_RS11135
uniprot id: A0A386HEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

1604335:DXZ79 RS04495
gene id: 1604335:DXZ79_RS04495
uniprot id: A0A386HBN4
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS05475
gene id: 1604335:DXZ79_RS05475
uniprot id: A0A386HC45
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1604335:DXZ79 RS03325
gene id: 1604335:DXZ79_RS03325
uniprot id: A0A8E4BM91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1604335:DXZ79 RS00630
gene id: 1604335:DXZ79_RS00630
uniprot id: A0A8D4MWU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1604335:DXZ79 RS15110
gene id: 1604335:DXZ79_RS15110
uniprot id: A0A386HGU3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS12755
gene id: 1604335:DXZ79_RS12755
uniprot id: A0A386HFS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1604335:DXZ79 RS15625
gene id: 1604335:DXZ79_RS15625
uniprot id: A0A386HH97
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1604335:DXZ79 RS08640
gene id: 1604335:DXZ79_RS08640
uniprot id: A0A386HDR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1604335:DXZ79 RS00975
gene id: 1604335:DXZ79_RS00975
uniprot id: A0A8D4SQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

1604335:DXZ79 RS07690
gene id: 1604335:DXZ79_RS07690
uniprot id: A0A386HDK6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

1604335:DXZ79 RS08520
gene id: 1604335:DXZ79_RS08520
uniprot id: A0A8D4N3X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

1604335:DXZ79 RS04055
gene id: 1604335:DXZ79_RS04055
uniprot id: A0A386HBG3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1604335:DXZ79 RS18335
gene id: 1604335:DXZ79_RS18335
uniprot id: A0A386HHW8
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS09625
gene id: 1604335:DXZ79_RS09625
uniprot id: A0A386HEE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.
messages: Membrane

1604335:DXZ79 RS12125
gene id: 1604335:DXZ79_RS12125
uniprot id: A0A386HEY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1604335:DXZ79 RS19015
gene id: 1604335:DXZ79_RS19015
uniprot id: A0A386HIZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1604335:DXZ79 RS18960
gene id: 1604335:DXZ79_RS18960
uniprot id: A0A386HIP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1604335:DXZ79 RS17725
gene id: 1604335:DXZ79_RS17725
uniprot id: A0A386HID1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1604335:DXZ79 RS03555
gene id: 1604335:DXZ79_RS03555
uniprot id: A0A8D4SQU4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1604335:DXZ79 RS09160
gene id: 1604335:DXZ79_RS09160
uniprot id: A0A8D4SMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS12595
gene id: 1604335:DXZ79_RS12595
uniprot id: A0A386HFL2
names: Similarity
messages: Belongs to the peptidase M1 family.

1604335:DXZ79 RS11275
gene id: 1604335:DXZ79_RS11275
uniprot id: A0A386HEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

1604335:DXZ79 RS10365
gene id: 1604335:DXZ79_RS10365
uniprot id: A0A386HEJ5
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS13445
gene id: 1604335:DXZ79_RS13445
uniprot id: A0A386HFZ5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1604335:DXZ79 RS11205
gene id: 1604335:DXZ79_RS11205
uniprot id: A0A386HEJ3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1604335:DXZ79 RS04805
gene id: 1604335:DXZ79_RS04805
uniprot id: A0A386HBN5
names: Subunit
messages: Monomer.

1604335:DXZ79 RS01490
gene id: 1604335:DXZ79_RS01490
uniprot id: A0A386H9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

1604335:DXZ79 RS10635
gene id: 1604335:DXZ79_RS10635
uniprot id: A0A386HEV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA gyrase inhibitor family.
messages: Cytoplasm
messages: Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
messages: Interacts with DNA gyrase.

1604335:DXZ79 RS00205
gene id: 1604335:DXZ79_RS00205
uniprot id: A0A386H9X9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS05630
gene id: 1604335:DXZ79_RS05630
uniprot id: A0A386HC91
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS09585
gene id: 1604335:DXZ79_RS09585
uniprot id: A0A386HDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

1604335:DXZ79 RS15560
gene id: 1604335:DXZ79_RS15560
uniprot id: A0A386HH18
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1604335:DXZ79 RS10835
gene id: 1604335:DXZ79_RS10835
uniprot id: A0A386HE76
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1604335:DXZ79 RS06225
gene id: 1604335:DXZ79_RS06225
uniprot id: A0A386HCW4
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS14065
gene id: 1604335:DXZ79_RS14065
uniprot id: A0A386HFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1604335:DXZ79 RS13255
gene id: 1604335:DXZ79_RS13255
uniprot id: A0A386HGR1
names: Similarity
messages: To H.influenzae HI_0842.

1604335:DXZ79 RS17930
gene id: 1604335:DXZ79_RS17930
uniprot id: A0A386HIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1604335:DXZ79 RS10160
gene id: 1604335:DXZ79_RS10160
uniprot id: A0A386HE73
names: Similarity
messages: Belongs to the SUI1 family.

1604335:DXZ79 RS15580
gene id: 1604335:DXZ79_RS15580
uniprot id: A0A386HGL0
names: Similarity
messages: Belongs to the skp family.

1604335:DXZ79 RS09525
gene id: 1604335:DXZ79_RS09525
uniprot id: A0A386HE55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

1604335:DXZ79 RS03475
gene id: 1604335:DXZ79_RS03475
uniprot id: A0A386HB04
names: Similarity
messages: Belongs to the threonine synthase family.

1604335:DXZ79 RS00490
gene id: 1604335:DXZ79_RS00490
uniprot id: A0A386H9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

1604335:DXZ79 RS15525
gene id: 1604335:DXZ79_RS15525
uniprot id: A0A8D4N4U7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1604335:DXZ79 RS00845
gene id: 1604335:DXZ79_RS00845
uniprot id: A0A386HA14
names: Similarity
messages: Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.

1604335:DXZ79 RS13545
gene id: 1604335:DXZ79_RS13545
uniprot id: A0A386HG15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1604335:DXZ79 RS19355
gene id: 1604335:DXZ79_RS19355
uniprot id: A0A386HIV6
names: Similarity
messages: Belongs to the HSP15 family.

1604335:DXZ79 RS18795
gene id: 1604335:DXZ79_RS18795
uniprot id: A0A386HIU3
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1604335:DXZ79 RS09700
gene id: 1604335:DXZ79_RS09700
uniprot id: A0A8E3ZIA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1604335:DXZ79 RS06460
gene id: 1604335:DXZ79_RS06460
uniprot id: A0A386HD06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS07725
gene id: 1604335:DXZ79_RS07725
uniprot id: A0A386HD99
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS12915
gene id: 1604335:DXZ79_RS12915
uniprot id: A0A386HFW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS18515
gene id: 1604335:DXZ79_RS18515
uniprot id: A0A386HIP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).
messages: sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE.

1604335:DXZ79 RS08215
gene id: 1604335:DXZ79_RS08215
uniprot id: A0A8D4SRX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS07540
gene id: 1604335:DXZ79_RS07540
uniprot id: A0A386HD61
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1604335:DXZ79 RS03635
gene id: 1604335:DXZ79_RS03635
uniprot id: A0A386HJT8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1604335:DXZ79 RS16710
gene id: 1604335:DXZ79_RS16710
uniprot id: A0A386HI27
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS16100
gene id: 1604335:DXZ79_RS16100
uniprot id: A0A386HHL2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

1604335:DXZ79 RS16350
gene id: 1604335:DXZ79_RS16350
uniprot id: A0A8D4N457
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1604335:DXZ79 RS14850
gene id: 1604335:DXZ79_RS14850
uniprot id: A0A386HG83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1604335:DXZ79 RS10285
gene id: 1604335:DXZ79_RS10285
uniprot id: A0A386HE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

1604335:DXZ79 RS02495
gene id: 1604335:DXZ79_RS02495
uniprot id: A0A386HAC6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS19520
gene id: 1604335:DXZ79_RS19520
uniprot id: A0A386HJU5
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS03510
gene id: 1604335:DXZ79_RS03510
uniprot id: A0A386HBD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1604335:DXZ79 RS16230
gene id: 1604335:DXZ79_RS16230
uniprot id: A0A386HI82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

1604335:DXZ79 RS09840
gene id: 1604335:DXZ79_RS09840
uniprot id: A0A386HDS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS07190
gene id: 1604335:DXZ79_RS07190
uniprot id: A0A386HCZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS09355
gene id: 1604335:DXZ79_RS09355
uniprot id: A0A386HDN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1604335:DXZ79 RS14585
gene id: 1604335:DXZ79_RS14585
uniprot id: A0A386HGW0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1604335:DXZ79 RS11675
gene id: 1604335:DXZ79_RS11675
uniprot id: A0A386HEQ7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1604335:DXZ79 RS14640
gene id: 1604335:DXZ79_RS14640
uniprot id: A0A386HH24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1604335:DXZ79 RS17320
gene id: 1604335:DXZ79_RS17320
uniprot id: A0A386HHY3
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

1604335:DXZ79 RS19085
gene id: 1604335:DXZ79_RS19085
uniprot id: A0A386HIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

1604335:DXZ79 RS18165
gene id: 1604335:DXZ79_RS18165
uniprot id: A0A386HJ69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

1604335:DXZ79 RS05175
gene id: 1604335:DXZ79_RS05175
uniprot id: A0A386HBH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

1604335:DXZ79 RS10380
gene id: 1604335:DXZ79_RS10380
uniprot id: A0A386HEP5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1604335:DXZ79 RS19950
gene id: 1604335:DXZ79_RS19950
uniprot id: A0A386HJ55
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1604335:DXZ79 RS02675
gene id: 1604335:DXZ79_RS02675
uniprot id: A0A386HB46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1604335:DXZ79 RS10770
gene id: 1604335:DXZ79_RS10770
uniprot id: A0A386HEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS02160
gene id: 1604335:DXZ79_RS02160
uniprot id: A0A386HAK7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1604335:DXZ79 RS06380
gene id: 1604335:DXZ79_RS06380
uniprot id: A0A386HCF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1604335:DXZ79 RS10975
gene id: 1604335:DXZ79_RS10975
uniprot id: A0A386HEF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS08500
gene id: 1604335:DXZ79_RS08500
uniprot id: A0A386HD89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1604335:DXZ79 RS06395
gene id: 1604335:DXZ79_RS06395
uniprot id: A0A386HC28
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1604335:DXZ79 RS02465
gene id: 1604335:DXZ79_RS02465
uniprot id: A0A8E4MBN3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1604335:DXZ79 RS05015
gene id: 1604335:DXZ79_RS05015
uniprot id: A0A386HBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1604335:DXZ79 RS12820
gene id: 1604335:DXZ79_RS12820
uniprot id: A0A386HFW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1604335:DXZ79 RS19080
gene id: 1604335:DXZ79_RS19080
uniprot id: A0A386HI81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

1604335:DXZ79 RS05280
gene id: 1604335:DXZ79_RS05280
uniprot id: A0A386HBJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1604335:DXZ79 RS02180
gene id: 1604335:DXZ79_RS02180
uniprot id: A0A386H9Y9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1604335:DXZ79 RS03140
gene id: 1604335:DXZ79_RS03140
uniprot id: A0A386HB08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family.
messages: Cytoplasm
messages: Homodecamer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.

1604335:DXZ79 RS01410
gene id: 1604335:DXZ79_RS01410
uniprot id: A0A8D4MYW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS07385
gene id: 1604335:DXZ79_RS07385
uniprot id: A0A386HCK3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11235
gene id: 1604335:DXZ79_RS11235
uniprot id: A0A386HFH4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1604335:DXZ79 RS15960
gene id: 1604335:DXZ79_RS15960
uniprot id: A0A386HGS9
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1604335:DXZ79 RS09870
gene id: 1604335:DXZ79_RS09870
uniprot id: A0A386HEB2
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1604335:DXZ79 RS01170
gene id: 1604335:DXZ79_RS01170
uniprot id: A0A386HAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

1604335:DXZ79 RS16215
gene id: 1604335:DXZ79_RS16215
uniprot id: A0A386HHU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1604335:DXZ79 RS11165
gene id: 1604335:DXZ79_RS11165
uniprot id: A0A386HEX7
names: Similarity
messages: Belongs to the HesB/IscA family.

1604335:DXZ79 RS07270
gene id: 1604335:DXZ79_RS07270
uniprot id: A0A8D4SRF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1604335:DXZ79 RS07425
gene id: 1604335:DXZ79_RS07425
uniprot id: A0A386HCX5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS11450
gene id: 1604335:DXZ79_RS11450
uniprot id: A0A386HEM5
names: Similarity
messages: Belongs to the fructosamine kinase family.

1604335:DXZ79 RS16315
gene id: 1604335:DXZ79_RS16315
uniprot id: A0A386HHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1604335:DXZ79 RS14905
gene id: 1604335:DXZ79_RS14905
uniprot id: A0A386HG93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1604335:DXZ79 RS05070
gene id: 1604335:DXZ79_RS05070
uniprot id: A0A386HBX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1604335:DXZ79 RS17710
gene id: 1604335:DXZ79_RS17710
uniprot id: A0A386HI52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS08735
gene id: 1604335:DXZ79_RS08735
uniprot id: A0A8D4SS05
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1604335:DXZ79 RS06455
gene id: 1604335:DXZ79_RS06455
uniprot id: A0A386HCN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS08040
gene id: 1604335:DXZ79_RS08040
uniprot id: A0A386HDT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1604335:DXZ79 RS09945
gene id: 1604335:DXZ79_RS09945
uniprot id: A0A386HDU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1604335:DXZ79 RS02535
gene id: 1604335:DXZ79_RS02535
uniprot id: A0A386HAR2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1604335:DXZ79 RS18985
gene id: 1604335:DXZ79_RS18985
uniprot id: A0A386HJ30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1604335:DXZ79 RS16790
gene id: 1604335:DXZ79_RS16790
uniprot id: A0A8D4N1Q8
names: Similarity
messages: Belongs to the HupF/HypC family.

1604335:DXZ79 RS14835
gene id: 1604335:DXZ79_RS14835
uniprot id: A0A386HGQ3
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1604335:DXZ79 RS11925
gene id: 1604335:DXZ79_RS11925
uniprot id: A0A386HFA3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS15510
gene id: 1604335:DXZ79_RS15510
uniprot id: A0A386HHV0
names: Similarity
messages: Belongs to the UPF0253 family.

1604335:DXZ79 RS04225
gene id: 1604335:DXZ79_RS04225
uniprot id: A0A386HBS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1604335:DXZ79 RS18585
gene id: 1604335:DXZ79_RS18585
uniprot id: A0A386HIL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1604335:DXZ79 RS14020
gene id: 1604335:DXZ79_RS14020
uniprot id: A0A386HGF7
names: Similarity
messages: Belongs to the UPF0381 family.

1604335:DXZ79 RS07575
gene id: 1604335:DXZ79_RS07575
uniprot id: A0A8D4MYU5
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS14725
gene id: 1604335:DXZ79_RS14725
uniprot id: A0A386HGN5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1604335:DXZ79 RS00905
gene id: 1604335:DXZ79_RS00905
uniprot id: A0A386H9L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1604335:DXZ79 RS07145
gene id: 1604335:DXZ79_RS07145
uniprot id: A0A8D4MYP8
names: Similarity
messages: Belongs to the peptidase S11 family.

1604335:DXZ79 RS09555
gene id: 1604335:DXZ79_RS09555
uniprot id: A0A386HE87
names: Similarity
messages: Belongs to the pyruvate kinase family.

1604335:DXZ79 RS19175
gene id: 1604335:DXZ79_RS19175
uniprot id: A0A386HIW2
names: Similarity
messages: Belongs to the UPF0270 family.

1604335:DXZ79 RS03180
gene id: 1604335:DXZ79_RS03180
uniprot id: A0A386HAZ7
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS10170
gene id: 1604335:DXZ79_RS10170
uniprot id: A0A386HDX6
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

1604335:DXZ79 RS16255
gene id: 1604335:DXZ79_RS16255
uniprot id: A0A386HHL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS07610
gene id: 1604335:DXZ79_RS07610
uniprot id: A0A386HD73
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS09070
gene id: 1604335:DXZ79_RS09070
uniprot id: A0A386HDD9
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS05390
gene id: 1604335:DXZ79_RS05390
uniprot id: A0A386HBL6
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

1604335:DXZ79 RS04230
gene id: 1604335:DXZ79_RS04230
uniprot id: A0A386HBJ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS04125
gene id: 1604335:DXZ79_RS04125
uniprot id: A0A8D4MZQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS05395
gene id: 1604335:DXZ79_RS05395
uniprot id: A0A386HCB7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1604335:DXZ79 RS11650
gene id: 1604335:DXZ79_RS11650
uniprot id: A0A386HF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1604335:DXZ79 RS16925
gene id: 1604335:DXZ79_RS16925
uniprot id: A0A8D4N322
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1604335:DXZ79 RS12295
gene id: 1604335:DXZ79_RS12295
uniprot id: A0A386HFV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MSOX/MTOX family. MTOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
messages: Monomer.

1604335:DXZ79 RS05440
gene id: 1604335:DXZ79_RS05440
uniprot id: A0A386HC54
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1604335:DXZ79 RS05365
gene id: 1604335:DXZ79_RS05365
uniprot id: A0A8D4SR44
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

1604335:DXZ79 RS19040
gene id: 1604335:DXZ79_RS19040
uniprot id: A0A386HJ84
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1604335:DXZ79 RS07845
gene id: 1604335:DXZ79_RS07845
uniprot id: A0A386HDC2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

1604335:DXZ79 RS00415
gene id: 1604335:DXZ79_RS00415
uniprot id: A0A8E4DF90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1604335:DXZ79 RS17405
gene id: 1604335:DXZ79_RS17405
uniprot id: A0A386HHG3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1604335:DXZ79 RS01230
gene id: 1604335:DXZ79_RS01230
uniprot id: A0A386HA85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1604335:DXZ79 RS02540
gene id: 1604335:DXZ79_RS02540
uniprot id: A0A386HAW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1604335:DXZ79 RS06505
gene id: 1604335:DXZ79_RS06505
uniprot id: A0A386HCP4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1604335:DXZ79 RS07515
gene id: 1604335:DXZ79_RS07515
uniprot id: A0A386HDG9
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS14070
gene id: 1604335:DXZ79_RS14070
uniprot id: A0A386HGG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1604335:DXZ79 RS12675
gene id: 1604335:DXZ79_RS12675
uniprot id: A0A386HFX6
names: Similarity
messages: Belongs to the UPF0434 family.

1604335:DXZ79 RS16295
gene id: 1604335:DXZ79_RS16295
uniprot id: A0A386HGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1604335:DXZ79 RS11085
gene id: 1604335:DXZ79_RS11085
uniprot id: A0A8D4SQY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS18575
gene id: 1604335:DXZ79_RS18575
uniprot id: A0A386HIW0
names: Cofactor
messages: Can also use Mn(2+) ion.

1604335:DXZ79 RS16335
gene id: 1604335:DXZ79_RS16335
uniprot id: A0A386HIA6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1604335:DXZ79 RS07745
gene id: 1604335:DXZ79_RS07745
uniprot id: A0A386HD64
names: Similarity
messages: Belongs to the UPF0265 family.

1604335:DXZ79 RS05690
gene id: 1604335:DXZ79_RS05690
uniprot id: A0A386HC99
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1604335:DXZ79 RS04985
gene id: 1604335:DXZ79_RS04985
uniprot id: A0A386HBI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1604335:DXZ79 RS14145
gene id: 1604335:DXZ79_RS14145
uniprot id: A0A8D4SNU1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS13695
gene id: 1604335:DXZ79_RS13695
uniprot id: A0A386HFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1604335:DXZ79 RS16340
gene id: 1604335:DXZ79_RS16340
uniprot id: A0A386HHG9
names: Similarity
messages: Belongs to the agmatine deiminase family.

1604335:DXZ79 RS09800
gene id: 1604335:DXZ79_RS09800
uniprot id: A0A386HER8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1604335:DXZ79 RS19470
gene id: 1604335:DXZ79_RS19470
uniprot id: A0A386HIY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

1604335:DXZ79 RS17325
gene id: 1604335:DXZ79_RS17325
uniprot id: A0A8D4N371
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1604335:DXZ79 RS09780
gene id: 1604335:DXZ79_RS09780
uniprot id: A0A386HED0
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1604335:DXZ79 RS16600
gene id: 1604335:DXZ79_RS16600
uniprot id: A0A386HH66
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1604335:DXZ79 RS03785
gene id: 1604335:DXZ79_RS03785
uniprot id: A0A386HBC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1604335:DXZ79 RS07450
gene id: 1604335:DXZ79_RS07450
uniprot id: A0A386HD44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1604335:DXZ79 RS13200
gene id: 1604335:DXZ79_RS13200
uniprot id: A0A386HFV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS17040
gene id: 1604335:DXZ79_RS17040
uniprot id: A0A8D4SRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS10070
gene id: 1604335:DXZ79_RS10070
uniprot id: A0A386HE13
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1604335:DXZ79 RS16725
gene id: 1604335:DXZ79_RS16725
uniprot id: A0A386HIG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS19230
gene id: 1604335:DXZ79_RS19230
uniprot id: A0A386HIT9
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1604335:DXZ79 RS18095
gene id: 1604335:DXZ79_RS18095
uniprot id: A0A386HIL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS07060
gene id: 1604335:DXZ79_RS07060
uniprot id: A0A386HCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1604335:DXZ79 RS12040
gene id: 1604335:DXZ79_RS12040
uniprot id: A0A386HEY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

1604335:DXZ79 RS09915
gene id: 1604335:DXZ79_RS09915
uniprot id: A0A386HDX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS10550
gene id: 1604335:DXZ79_RS10550
uniprot id: A0A386HES4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1604335:DXZ79 RS17275
gene id: 1604335:DXZ79_RS17275
uniprot id: A0A386HIR2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1604335:DXZ79 RS10405
gene id: 1604335:DXZ79_RS10405
uniprot id: A0A386HEU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS13805
gene id: 1604335:DXZ79_RS13805
uniprot id: A0A386HFP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
messages: Belongs to the flk family.
messages: Cell inner membrane

1604335:DXZ79 RS05500
gene id: 1604335:DXZ79_RS05500
uniprot id: A0A386HBN6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1604335:DXZ79 RS14220
gene id: 1604335:DXZ79_RS14220
uniprot id: A0A386HGD1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1604335:DXZ79 RS02435
gene id: 1604335:DXZ79_RS02435
uniprot id: A0A386HAB5
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS15120
gene id: 1604335:DXZ79_RS15120
uniprot id: A0A386HGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1604335:DXZ79 RS20440
gene id: 1604335:DXZ79_RS20440
uniprot id: A0A386HJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS03755
gene id: 1604335:DXZ79_RS03755
uniprot id: A0A386HAT7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1604335:DXZ79 RS01245
gene id: 1604335:DXZ79_RS01245
uniprot id: A0A386H9T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

1604335:DXZ79 RS18680
gene id: 1604335:DXZ79_RS18680
uniprot id: A0A386HIN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1604335:DXZ79 RS15050
gene id: 1604335:DXZ79_RS15050
uniprot id: A0A386HGD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1604335:DXZ79 RS12945
gene id: 1604335:DXZ79_RS12945
uniprot id: A0A8E4BJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS11775
gene id: 1604335:DXZ79_RS11775
uniprot id: A0A386HFC3
names: Similarity
messages: Belongs to the UPF0181 family.

1604335:DXZ79 RS12515
gene id: 1604335:DXZ79_RS12515
uniprot id: A0A386HFQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

1604335:DXZ79 RS20510
gene id: 1604335:DXZ79_RS20510
uniprot id: A0A386HIY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1604335:DXZ79 RS10525
gene id: 1604335:DXZ79_RS10525
uniprot id: A0A386HEW3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1604335:DXZ79 RS12900
gene id: 1604335:DXZ79_RS12900
uniprot id: A0A8E4BML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS07685
gene id: 1604335:DXZ79_RS07685
uniprot id: A0A386HD47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

1604335:DXZ79 RS10910
gene id: 1604335:DXZ79_RS10910
uniprot id: A0A386HF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS11080
gene id: 1604335:DXZ79_RS11080
uniprot id: A0A386HF38
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS01440
gene id: 1604335:DXZ79_RS01440
uniprot id: A0A8D4N3A8
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

1604335:DXZ79 RS04520
gene id: 1604335:DXZ79_RS04520
uniprot id: A0A386HBV7
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1604335:DXZ79 RS18060
gene id: 1604335:DXZ79_RS18060
uniprot id: A0A386HKD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

1604335:DXZ79 RS00575
gene id: 1604335:DXZ79_RS00575
uniprot id: A0A386H9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1604335:DXZ79 RS10345
gene id: 1604335:DXZ79_RS10345
uniprot id: A0A8D4SRY5
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS18185
gene id: 1604335:DXZ79_RS18185
uniprot id: A0A386HHT8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1604335:DXZ79 RS00060
gene id: 1604335:DXZ79_RS00060
uniprot id: A0A386H926
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS13405
gene id: 1604335:DXZ79_RS13405
uniprot id: A0A386HG37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
messages: Homodimer.
messages: Periplasm

1604335:DXZ79 RS03520
gene id: 1604335:DXZ79_RS03520
uniprot id: A0A386HB74
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1604335:DXZ79 RS19265
gene id: 1604335:DXZ79_RS19265
uniprot id: A0A386HJ18
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1604335:DXZ79 RS05110
gene id: 1604335:DXZ79_RS05110
uniprot id: A0A8D4N009
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1604335:DXZ79 RS16980
gene id: 1604335:DXZ79_RS16980
uniprot id: A0A386HI24
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS18930
gene id: 1604335:DXZ79_RS18930
uniprot id: A0A386HIV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1604335:DXZ79 RS05680
gene id: 1604335:DXZ79_RS05680
uniprot id: A0A386HCG4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1604335:DXZ79 RS08615
gene id: 1604335:DXZ79_RS08615
uniprot id: A0A386HDH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1604335:DXZ79 RS05715
gene id: 1604335:DXZ79_RS05715
uniprot id: A0A386HCJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1604335:DXZ79 RS07995
gene id: 1604335:DXZ79_RS07995
uniprot id: A0A8D4N4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1604335:DXZ79 RS02590
gene id: 1604335:DXZ79_RS02590
uniprot id: A0A8D4N251
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS18070
gene id: 1604335:DXZ79_RS18070
uniprot id: A0A386HII8
names: Similarity
messages: Belongs to the peptidase U62 family.

1604335:DXZ79 RS12215
gene id: 1604335:DXZ79_RS12215
uniprot id: A0A386HF93
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1604335:DXZ79 RS09090
gene id: 1604335:DXZ79_RS09090
uniprot id: A0A386HE50
names: Similarity
messages: Belongs to the UPF0423 family.

1604335:DXZ79 RS18075
gene id: 1604335:DXZ79_RS18075
uniprot id: A0A386HHS5
names: Similarity
messages: Belongs to the UPF0307 family.

1604335:DXZ79 RS00525
gene id: 1604335:DXZ79_RS00525
uniprot id: A0A386H9L8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1604335:DXZ79 RS00785
gene id: 1604335:DXZ79_RS00785
uniprot id: A0A8D4MYQ7
names: Similarity
messages: Belongs to the UPF0438 family.

1604335:DXZ79 RS11065
gene id: 1604335:DXZ79_RS11065
uniprot id: A0A386HEB6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1604335:DXZ79 RS01250
gene id: 1604335:DXZ79_RS01250
uniprot id: A0A386HA78
names: Similarity
messages: Belongs to the leucine-binding protein family.

1604335:DXZ79 RS05695
gene id: 1604335:DXZ79_RS05695
uniprot id: A0A386HCN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1604335:DXZ79 RS09615
gene id: 1604335:DXZ79_RS09615
uniprot id: A0A386HEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1604335:DXZ79 RS15570
gene id: 1604335:DXZ79_RS15570
uniprot id: A0A386HH36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1604335:DXZ79 RS13150
gene id: 1604335:DXZ79_RS13150
uniprot id: A0A386HFZ8
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1604335:DXZ79 RS17870
gene id: 1604335:DXZ79_RS17870
uniprot id: A0A8E4BMK2
names: Similarity
messages: Belongs to the peptidase S1C family.

1604335:DXZ79 RS13115
gene id: 1604335:DXZ79_RS13115
uniprot id: A0A386HG50
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1604335:DXZ79 RS14195
gene id: 1604335:DXZ79_RS14195
uniprot id: A0A386HFW6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1604335:DXZ79 RS03745
gene id: 1604335:DXZ79_RS03745
uniprot id: A0A386HB54
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS10260
gene id: 1604335:DXZ79_RS10260
uniprot id: A0A386HEH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1604335:DXZ79 RS16880
gene id: 1604335:DXZ79_RS16880
uniprot id: A0A386HI03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1604335:DXZ79 RS12510
gene id: 1604335:DXZ79_RS12510
uniprot id: A0A386HF45
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

1604335:DXZ79 RS19815
gene id: 1604335:DXZ79_RS19815
uniprot id: A0A386HJZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1604335:DXZ79 RS04060
gene id: 1604335:DXZ79_RS04060
uniprot id: A0A386HBM8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1604335:DXZ79 RS09510
gene id: 1604335:DXZ79_RS09510
uniprot id: A0A386HE72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1604335:DXZ79 RS07320
gene id: 1604335:DXZ79_RS07320
uniprot id: A0A386HD16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

1604335:DXZ79 RS18935
gene id: 1604335:DXZ79_RS18935
uniprot id: A0A386HJ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1604335:DXZ79 RS18090
gene id: 1604335:DXZ79_RS18090
uniprot id: A0A386HIH6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1604335:DXZ79 RS16360
gene id: 1604335:DXZ79_RS16360
uniprot id: A0A386HH00
names: Similarity
messages: Belongs to the YggT family.

1604335:DXZ79 RS04500
gene id: 1604335:DXZ79_RS04500
uniprot id: A0A386HB89
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS05305
gene id: 1604335:DXZ79_RS05305
uniprot id: A0A386HBT5
names: Similarity
messages: Belongs to the P(II) protein family.

1604335:DXZ79 RS08705
gene id: 1604335:DXZ79_RS08705
uniprot id: A0A386HDS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

1604335:DXZ79 RS05220
gene id: 1604335:DXZ79_RS05220
uniprot id: A0A386HBM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1604335:DXZ79 RS02640
gene id: 1604335:DXZ79_RS02640
uniprot id: A0A8D4MZA4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1604335:DXZ79 RS01445
gene id: 1604335:DXZ79_RS01445
uniprot id: A0A386HAI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1604335:DXZ79 RS01115
gene id: 1604335:DXZ79_RS01115
uniprot id: A0A386H9K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1604335:DXZ79 RS14845
gene id: 1604335:DXZ79_RS14845
uniprot id: A0A386HG80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1604335:DXZ79 RS07520
gene id: 1604335:DXZ79_RS07520
uniprot id: A0A386HCT1
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS19160
gene id: 1604335:DXZ79_RS19160
uniprot id: A0A386HJ64
names: Similarity
messages: Belongs to the PhzF family.

1604335:DXZ79 RS01585
gene id: 1604335:DXZ79_RS01585
uniprot id: A0A386HA33
names: Similarity
messages: Belongs to the MxiH/PrgI/YscF family.

1604335:DXZ79 RS15185
gene id: 1604335:DXZ79_RS15185
uniprot id: A0A386HGD6
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS13750
gene id: 1604335:DXZ79_RS13750
uniprot id: A0A386HFN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS04355
gene id: 1604335:DXZ79_RS04355
uniprot id: A0A8D4MXX8
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS04595
gene id: 1604335:DXZ79_RS04595
uniprot id: A0A386HBK5
names: Function
names: Similarity
messages: Belongs to the TorD/DmsD family. DmsD subfamily.
messages: Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.

1604335:DXZ79 RS00375
gene id: 1604335:DXZ79_RS00375
uniprot id: A0A386H973
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1604335:DXZ79 RS02595
gene id: 1604335:DXZ79_RS02595
uniprot id: A0A386HAX8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1604335:DXZ79 RS09210
gene id: 1604335:DXZ79_RS09210
uniprot id: A0A386HEE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS04865
gene id: 1604335:DXZ79_RS04865
uniprot id: A0A8D4SRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS10140
gene id: 1604335:DXZ79_RS10140
uniprot id: A0A386HEN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1604335:DXZ79 RS03890
gene id: 1604335:DXZ79_RS03890
uniprot id: A0A386HB28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1604335:DXZ79 RS03575
gene id: 1604335:DXZ79_RS03575
uniprot id: A0A386HB84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1604335:DXZ79 RS03640
gene id: 1604335:DXZ79_RS03640
uniprot id: A0A386HB36
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1604335:DXZ79 RS19845
gene id: 1604335:DXZ79_RS19845
uniprot id: A0A386HIK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1604335:DXZ79 RS14960
gene id: 1604335:DXZ79_RS14960
uniprot id: A0A386HGA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1604335:DXZ79 RS17940
gene id: 1604335:DXZ79_RS17940
uniprot id: A0A386HI90
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1604335:DXZ79 RS08675
gene id: 1604335:DXZ79_RS08675
uniprot id: A0A386HDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1604335:DXZ79 RS04295
gene id: 1604335:DXZ79_RS04295
uniprot id: A0A386HBR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS14745
gene id: 1604335:DXZ79_RS14745
uniprot id: A0A386HG60
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS08545
gene id: 1604335:DXZ79_RS08545
uniprot id: A0A386HDP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS17240
gene id: 1604335:DXZ79_RS17240
uniprot id: A0A386HHD9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1604335:DXZ79 RS10185
gene id: 1604335:DXZ79_RS10185
uniprot id: A0A386HEL0
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS00650
gene id: 1604335:DXZ79_RS00650
uniprot id: A0A8D4N0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1604335:DXZ79 RS04255
gene id: 1604335:DXZ79_RS04255
uniprot id: A0A386HBT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS08710
gene id: 1604335:DXZ79_RS08710
uniprot id: A0A386HK21
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS10505
gene id: 1604335:DXZ79_RS10505
uniprot id: A0A386HEQ3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11875
gene id: 1604335:DXZ79_RS11875
uniprot id: A0A386HF29
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS00710
gene id: 1604335:DXZ79_RS00710
uniprot id: A0A386H9V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

1604335:DXZ79 RS11105
gene id: 1604335:DXZ79_RS11105
uniprot id: A0A386HFE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

1604335:DXZ79 RS15680
gene id: 1604335:DXZ79_RS15680
uniprot id: A0A386HGM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

1604335:DXZ79 RS09845
gene id: 1604335:DXZ79_RS09845
uniprot id: A0A386HEE4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

1604335:DXZ79 RS09570
gene id: 1604335:DXZ79_RS09570
uniprot id: A0A386HDS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS06450
gene id: 1604335:DXZ79_RS06450
uniprot id: A0A386HCU7
names: Function
names: Similarity
messages: Belongs to the IUNH family. RihA subfamily.
messages: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.

1604335:DXZ79 RS20100
gene id: 1604335:DXZ79_RS20100
uniprot id: A0A386HJR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1604335:DXZ79 RS14165
gene id: 1604335:DXZ79_RS14165
uniprot id: A0A386HGC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1604335:DXZ79 RS08300
gene id: 1604335:DXZ79_RS08300
uniprot id: A0A8D4SRY0
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS06925
gene id: 1604335:DXZ79_RS06925
uniprot id: A0A386HCC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1604335:DXZ79 RS09230
gene id: 1604335:DXZ79_RS09230
uniprot id: A0A386HDG1
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1604335:DXZ79 RS13670
gene id: 1604335:DXZ79_RS13670
uniprot id: A0A386HGY2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1604335:DXZ79 RS04715
gene id: 1604335:DXZ79_RS04715
uniprot id: A0A386HC11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1604335:DXZ79 RS17715
gene id: 1604335:DXZ79_RS17715
uniprot id: A0A386HIY8
names: Similarity
messages: Belongs to the pirin family.

1604335:DXZ79 RS13315
gene id: 1604335:DXZ79_RS13315
uniprot id: A0A386HFX3
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1604335:DXZ79 RS01210
gene id: 1604335:DXZ79_RS01210
uniprot id: A0A386H9J2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1604335:DXZ79 RS03310
gene id: 1604335:DXZ79_RS03310
uniprot id: A0A8D4MZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1604335:DXZ79 RS17150
gene id: 1604335:DXZ79_RS17150
uniprot id: A0A386HIB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1604335:DXZ79 RS04515
gene id: 1604335:DXZ79_RS04515
uniprot id: A0A386HBP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1604335:DXZ79 RS14135
gene id: 1604335:DXZ79_RS14135
uniprot id: A0A386HFV8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS12200
gene id: 1604335:DXZ79_RS12200
uniprot id: A0A386HF07
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1604335:DXZ79 RS07065
gene id: 1604335:DXZ79_RS07065
uniprot id: A0A8D4MYN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1604335:DXZ79 RS13560
gene id: 1604335:DXZ79_RS13560
uniprot id: A0A386HG66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1604335:DXZ79 RS18730
gene id: 1604335:DXZ79_RS18730
uniprot id: A0A386HIP1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1604335:DXZ79 RS03410
gene id: 1604335:DXZ79_RS03410
uniprot id: A0A386HBE7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS03435
gene id: 1604335:DXZ79_RS03435
uniprot id: A0A386HBC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1604335:DXZ79 RS09470
gene id: 1604335:DXZ79_RS09470
uniprot id: A0A8D4N512
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS06690
gene id: 1604335:DXZ79_RS06690
uniprot id: A0A8D4SRB7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1604335:DXZ79 RS11795
gene id: 1604335:DXZ79_RS11795
uniprot id: A0A386HFD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat-stable enterotoxin family.
messages: Secreted

1604335:DXZ79 RS12665
gene id: 1604335:DXZ79_RS12665
uniprot id: A0A386HF67
names: Similarity
messages: Belongs to the fructosamine kinase family.

1604335:DXZ79 RS05020
gene id: 1604335:DXZ79_RS05020
uniprot id: A0A386HC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS05750
gene id: 1604335:DXZ79_RS05750
uniprot id: A0A386HCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

1604335:DXZ79 RS19775
gene id: 1604335:DXZ79_RS19775
uniprot id: A0A8D4N8G1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1604335:DXZ79 RS02195
gene id: 1604335:DXZ79_RS02195
uniprot id: A0A386HAK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1604335:DXZ79 RS08020
gene id: 1604335:DXZ79_RS08020
uniprot id: A0A386HD12
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1604335:DXZ79 RS18065
gene id: 1604335:DXZ79_RS18065
uniprot id: A0A386HIB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

1604335:DXZ79 RS03875
gene id: 1604335:DXZ79_RS03875
uniprot id: A0A386HBL0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1604335:DXZ79 RS11820
gene id: 1604335:DXZ79_RS11820
uniprot id: A0A386HFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS10605
gene id: 1604335:DXZ79_RS10605
uniprot id: A0A386HF53
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

1604335:DXZ79 RS11425
gene id: 1604335:DXZ79_RS11425
uniprot id: A0A386HFS8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1604335:DXZ79 RS08130
gene id: 1604335:DXZ79_RS08130
uniprot id: A0A8D4SRK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS12375
gene id: 1604335:DXZ79_RS12375
uniprot id: A0A8D4SNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family. OpgC subfamily.
messages: Cell membrane
messages: Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.

1604335:DXZ79 RS08200
gene id: 1604335:DXZ79_RS08200
uniprot id: A0A8D4N0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1604335:DXZ79 RS20170
gene id: 1604335:DXZ79_RS20170
uniprot id: A0A386HK51
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1604335:DXZ79 RS07545
gene id: 1604335:DXZ79_RS07545
uniprot id: A0A386HCM8
names: Similarity
messages: Belongs to the HupF/HypC family.

1604335:DXZ79 RS09545
gene id: 1604335:DXZ79_RS09545
uniprot id: A0A386HDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

1604335:DXZ79 RS05935
gene id: 1604335:DXZ79_RS05935
uniprot id: A0A386HCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
messages: Catalyzes the proton-dependent transport of sialic acid.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS11010
gene id: 1604335:DXZ79_RS11010
uniprot id: A0A8D4N1T7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1604335:DXZ79 RS00495
gene id: 1604335:DXZ79_RS00495
uniprot id: A0A386HA26
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

1604335:DXZ79 RS15645
gene id: 1604335:DXZ79_RS15645
uniprot id: A0A386HHE2
names: Similarity
messages: Belongs to the UPF0325 family.

1604335:DXZ79 RS12520
gene id: 1604335:DXZ79_RS12520
uniprot id: A0A386HFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

1604335:DXZ79 RS02570
gene id: 1604335:DXZ79_RS02570
uniprot id: A0A386HAQ4
names: Similarity
messages: Belongs to the peptidase S13 family.

1604335:DXZ79 RS16970
gene id: 1604335:DXZ79_RS16970
uniprot id: A0A386HHA2
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1604335:DXZ79 RS10970
gene id: 1604335:DXZ79_RS10970
uniprot id: A0A386HF47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1604335:DXZ79 RS16815
gene id: 1604335:DXZ79_RS16815
uniprot id: A0A386HH64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1604335:DXZ79 RS19445
gene id: 1604335:DXZ79_RS19445
uniprot id: A0A386HJB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1604335:DXZ79 RS07120
gene id: 1604335:DXZ79_RS07120
uniprot id: A0A386HCU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1604335:DXZ79 RS11790
gene id: 1604335:DXZ79_RS11790
uniprot id: A0A386HES7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1604335:DXZ79 RS12405
gene id: 1604335:DXZ79_RS12405
uniprot id: A0A386HFR8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1604335:DXZ79 RS00540
gene id: 1604335:DXZ79_RS00540
uniprot id: A0A386H9A3
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1604335:DXZ79 RS13665
gene id: 1604335:DXZ79_RS13665
uniprot id: A0A386HG34
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS12075
gene id: 1604335:DXZ79_RS12075
uniprot id: A0A386HFH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1604335:DXZ79 RS15285
gene id: 1604335:DXZ79_RS15285
uniprot id: A0A386HGF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1604335:DXZ79 RS16245
gene id: 1604335:DXZ79_RS16245
uniprot id: A0A386HGX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1604335:DXZ79 RS04290
gene id: 1604335:DXZ79_RS04290
uniprot id: A0A386HBK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS02355
gene id: 1604335:DXZ79_RS02355
uniprot id: A0A386HA20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1604335:DXZ79 RS09060
gene id: 1604335:DXZ79_RS09060
uniprot id: A0A386HDP6
names: Similarity
messages: Belongs to the hyi family.

1604335:DXZ79 RS00165
gene id: 1604335:DXZ79_RS00165
uniprot id: A0A386H9A8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS03145
gene id: 1604335:DXZ79_RS03145
uniprot id: A0A386HB77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS02130
gene id: 1604335:DXZ79_RS02130
uniprot id: A0A386H9Y0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1604335:DXZ79 RS17650
gene id: 1604335:DXZ79_RS17650
uniprot id: A0A386HI42
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1604335:DXZ79 RS00835
gene id: 1604335:DXZ79_RS00835
uniprot id: A0A386HA11
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS17095
gene id: 1604335:DXZ79_RS17095
uniprot id: A0A386HI44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1604335:DXZ79 RS15125
gene id: 1604335:DXZ79_RS15125
uniprot id: A0A386HGZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1604335:DXZ79 RS06985
gene id: 1604335:DXZ79_RS06985
uniprot id: A0A386HD22
names: Similarity
messages: Belongs to the ModE family.

1604335:DXZ79 RS03155
gene id: 1604335:DXZ79_RS03155
uniprot id: A0A8D4MXJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS07790
gene id: 1604335:DXZ79_RS07790
uniprot id: A0A386HDA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family. PduW subfamily.
messages: Cytoplasm

1604335:DXZ79 RS06360
gene id: 1604335:DXZ79_RS06360
uniprot id: A0A386HCY6
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS15630
gene id: 1604335:DXZ79_RS15630
uniprot id: A0A386HGL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1604335:DXZ79 RS03650
gene id: 1604335:DXZ79_RS03650
uniprot id: A0A386HAR5
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1604335:DXZ79 RS14895
gene id: 1604335:DXZ79_RS14895
uniprot id: A0A386HGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1604335:DXZ79 RS16985
gene id: 1604335:DXZ79_RS16985
uniprot id: A0A386HI84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1604335:DXZ79 RS18385
gene id: 1604335:DXZ79_RS18385
uniprot id: A0A386HHX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1604335:DXZ79 RS20445
gene id: 1604335:DXZ79_RS20445
uniprot id: A0A386HKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS04560
gene id: 1604335:DXZ79_RS04560
uniprot id: A0A386HBX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS16115
gene id: 1604335:DXZ79_RS16115
uniprot id: A0A8D4N850
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS07980
gene id: 1604335:DXZ79_RS07980
uniprot id: A0A8D4N3S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1604335:DXZ79 RS03830
gene id: 1604335:DXZ79_RS03830
uniprot id: A0A8E3ZHN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1604335:DXZ79 RS18840
gene id: 1604335:DXZ79_RS18840
uniprot id: A0A8E3ZHZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1604335:DXZ79 RS17775
gene id: 1604335:DXZ79_RS17775
uniprot id: A0A386HIZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1604335:DXZ79 RS05100
gene id: 1604335:DXZ79_RS05100
uniprot id: A0A386HJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1604335:DXZ79 RS08575
gene id: 1604335:DXZ79_RS08575
uniprot id: A0A386HD68
names: Similarity
messages: Belongs to the peptidase S8 family.

1604335:DXZ79 RS13380
gene id: 1604335:DXZ79_RS13380
uniprot id: A0A386HFY2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1604335:DXZ79 RS12770
gene id: 1604335:DXZ79_RS12770
uniprot id: A0A386HFV4
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1604335:DXZ79 RS07455
gene id: 1604335:DXZ79_RS07455
uniprot id: A0A386HDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1604335:DXZ79 RS14525
gene id: 1604335:DXZ79_RS14525
uniprot id: A0A386HG22
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1604335:DXZ79 RS12980
gene id: 1604335:DXZ79_RS12980
uniprot id: A0A386HF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

1604335:DXZ79 RS05685
gene id: 1604335:DXZ79_RS05685
uniprot id: A0A386HKL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1604335:DXZ79 RS04900
gene id: 1604335:DXZ79_RS04900
uniprot id: A0A386HBL3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1604335:DXZ79 RS11220
gene id: 1604335:DXZ79_RS11220
uniprot id: A0A386HFA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1604335:DXZ79 RS08145
gene id: 1604335:DXZ79_RS08145
uniprot id: A0A8D4N2H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

1604335:DXZ79 RS06930
gene id: 1604335:DXZ79_RS06930
uniprot id: A0A386HCA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1604335:DXZ79 RS14840
gene id: 1604335:DXZ79_RS14840
uniprot id: A0A386HGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Membrane

1604335:DXZ79 RS07415
gene id: 1604335:DXZ79_RS07415
uniprot id: A0A386HDF1
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1604335:DXZ79 RS07090
gene id: 1604335:DXZ79_RS07090
uniprot id: A0A386HCF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS08070
gene id: 1604335:DXZ79_RS08070
uniprot id: A0A386HDG2
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS10650
gene id: 1604335:DXZ79_RS10650
uniprot id: A0A386HE98
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1604335:DXZ79 RS03535
gene id: 1604335:DXZ79_RS03535
uniprot id: A0A386HB55
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1604335:DXZ79 RS04035
gene id: 1604335:DXZ79_RS04035
uniprot id: A0A386HBE8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1604335:DXZ79 RS08210
gene id: 1604335:DXZ79_RS08210
uniprot id: A0A8D4SRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS12345
gene id: 1604335:DXZ79_RS12345
uniprot id: A0A386HJX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1604335:DXZ79 RS18465
gene id: 1604335:DXZ79_RS18465
uniprot id: A0A386HIB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1604335:DXZ79 RS11340
gene id: 1604335:DXZ79_RS11340
uniprot id: A0A386HF11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1604335:DXZ79 RS03825
gene id: 1604335:DXZ79_RS03825
uniprot id: A0A386HBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1604335:DXZ79 RS01255
gene id: 1604335:DXZ79_RS01255
uniprot id: A0A386HAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS13050
gene id: 1604335:DXZ79_RS13050
uniprot id: A0A386HFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1604335:DXZ79 RS15600
gene id: 1604335:DXZ79_RS15600
uniprot id: A0A386HHI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1604335:DXZ79 RS06800
gene id: 1604335:DXZ79_RS06800
uniprot id: A0A386HD65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1604335:DXZ79 RS05355
gene id: 1604335:DXZ79_RS05355
uniprot id: A0A386HBU5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1604335:DXZ79 RS04310
gene id: 1604335:DXZ79_RS04310
uniprot id: A0A386HBU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1604335:DXZ79 RS04070
gene id: 1604335:DXZ79_RS04070
uniprot id: A0A386HBH6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1604335:DXZ79 RS06780
gene id: 1604335:DXZ79_RS06780
uniprot id: A0A386HCB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1604335:DXZ79 RS03580
gene id: 1604335:DXZ79_RS03580
uniprot id: A0A386HBH3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1604335:DXZ79 RS00865
gene id: 1604335:DXZ79_RS00865
uniprot id: A0A386H9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1604335:DXZ79 RS09235
gene id: 1604335:DXZ79_RS09235
uniprot id: A0A386HE27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1604335:DXZ79 RS13385
gene id: 1604335:DXZ79_RS13385
uniprot id: A0A386HKV1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1604335:DXZ79 RS12485
gene id: 1604335:DXZ79_RS12485
uniprot id: A0A386HFJ4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1604335:DXZ79 RS17390
gene id: 1604335:DXZ79_RS17390
uniprot id: A0A386HIT4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS00565
gene id: 1604335:DXZ79_RS00565
uniprot id: A0A386H9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

1604335:DXZ79 RS00145
gene id: 1604335:DXZ79_RS00145
uniprot id: A0A386H9X2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1604335:DXZ79 RS03720
gene id: 1604335:DXZ79_RS03720
uniprot id: A0A386HBA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1604335:DXZ79 RS07880
gene id: 1604335:DXZ79_RS07880
uniprot id: A0A386HCU3
names: Subcellular Location Annotation
messages: Bacterial microcompartment

1604335:DXZ79 RS00050
gene id: 1604335:DXZ79_RS00050
uniprot id: A0A386H9F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1604335:DXZ79 RS05625
gene id: 1604335:DXZ79_RS05625
uniprot id: A0A386HCF6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1604335:DXZ79 RS13700
gene id: 1604335:DXZ79_RS13700
uniprot id: A0A386HGA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1604335:DXZ79 RS08315
gene id: 1604335:DXZ79_RS08315
uniprot id: A0A386HD58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1604335:DXZ79 RS17560
gene id: 1604335:DXZ79_RS17560
uniprot id: A0A8D4N4L1
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS15550
gene id: 1604335:DXZ79_RS15550
uniprot id: A0A8E4GYB3
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS15335
gene id: 1604335:DXZ79_RS15335
uniprot id: A0A386HGG7
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1604335:DXZ79 RS03790
gene id: 1604335:DXZ79_RS03790
uniprot id: A0A386HBK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1604335:DXZ79 RS17125
gene id: 1604335:DXZ79_RS17125
uniprot id: A0A8D4SRW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1604335:DXZ79 RS15320
gene id: 1604335:DXZ79_RS15320
uniprot id: A0A386HHR7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1604335:DXZ79 RS14060
gene id: 1604335:DXZ79_RS14060
uniprot id: A0A386HFU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1604335:DXZ79 RS18105
gene id: 1604335:DXZ79_RS18105
uniprot id: A0A386HI51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

1604335:DXZ79 RS00185
gene id: 1604335:DXZ79_RS00185
uniprot id: A0A386H9G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1604335:DXZ79 RS08320
gene id: 1604335:DXZ79_RS08320
uniprot id: A0A386HDE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1604335:DXZ79 RS05540
gene id: 1604335:DXZ79_RS05540
uniprot id: A0A386HC19
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

1604335:DXZ79 RS18455
gene id: 1604335:DXZ79_RS18455
uniprot id: A0A386HKR8
names: Similarity
messages: Belongs to the Fur family.

1604335:DXZ79 RS16485
gene id: 1604335:DXZ79_RS16485
uniprot id: A0A8D4N6L5
names: Similarity
messages: Belongs to the transposase 8 family.

1604335:DXZ79 RS17805
gene id: 1604335:DXZ79_RS17805
uniprot id: A0A386HHM6
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1604335:DXZ79 RS17355
gene id: 1604335:DXZ79_RS17355
uniprot id: A0A386HI47
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11860
gene id: 1604335:DXZ79_RS11860
uniprot id: A0A386HEV2
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS20225
gene id: 1604335:DXZ79_RS20225
uniprot id: A0A386HJA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1604335:DXZ79 RS12995
gene id: 1604335:DXZ79_RS12995
uniprot id: A0A386HFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1604335:DXZ79 RS08620
gene id: 1604335:DXZ79_RS08620
uniprot id: A0A386HDS1
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1604335:DXZ79 RS05465
gene id: 1604335:DXZ79_RS05465
uniprot id: A0A386HCJ4
names: Similarity
messages: Belongs to the YfgM family.

1604335:DXZ79 RS13570
gene id: 1604335:DXZ79_RS13570
uniprot id: A0A8D4N548
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1604335:DXZ79 RS05600
gene id: 1604335:DXZ79_RS05600
uniprot id: A0A386HC78
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

1604335:DXZ79 RS06595
gene id: 1604335:DXZ79_RS06595
uniprot id: A0A386HCD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS11570
gene id: 1604335:DXZ79_RS11570
uniprot id: A0A386HF90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

1604335:DXZ79 RS02220
gene id: 1604335:DXZ79_RS02220
uniprot id: A0A386HAX4
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1604335:DXZ79 RS01060
gene id: 1604335:DXZ79_RS01060
uniprot id: A0A386H9G7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

1604335:DXZ79 RS08655
gene id: 1604335:DXZ79_RS08655
uniprot id: A0A8D4N2P1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1604335:DXZ79 RS13710
gene id: 1604335:DXZ79_RS13710
uniprot id: A0A386HGL3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS02585
gene id: 1604335:DXZ79_RS02585
uniprot id: A0A386HB01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1604335:DXZ79 RS11160
gene id: 1604335:DXZ79_RS11160
uniprot id: A0A386HEI8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1604335:DXZ79 RS05555
gene id: 1604335:DXZ79_RS05555
uniprot id: A0A8D4N4L2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1604335:DXZ79 RS07935
gene id: 1604335:DXZ79_RS07935
uniprot id: A0A8D4N384
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1604335:DXZ79 RS12050
gene id: 1604335:DXZ79_RS12050
uniprot id: A0A386HG24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1604335:DXZ79 RS17065
gene id: 1604335:DXZ79_RS17065
uniprot id: A0A386HHU0
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

1604335:DXZ79 RS06730
gene id: 1604335:DXZ79_RS06730
uniprot id: A0A386HCA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1604335:DXZ79 RS13990
gene id: 1604335:DXZ79_RS13990
uniprot id: A0A386HH37
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1604335:DXZ79 RS07570
gene id: 1604335:DXZ79_RS07570
uniprot id: A0A386HCU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS13415
gene id: 1604335:DXZ79_RS13415
uniprot id: A0A386HFI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1604335:DXZ79 RS08645
gene id: 1604335:DXZ79_RS08645
uniprot id: A0A8D4N1K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1604335:DXZ79 RS04700
gene id: 1604335:DXZ79_RS04700
uniprot id: A0A386HBY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1604335:DXZ79 RS03365
gene id: 1604335:DXZ79_RS03365
uniprot id: A0A386HAY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1604335:DXZ79 RS12765
gene id: 1604335:DXZ79_RS12765
uniprot id: A0A386HF87
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS04935
gene id: 1604335:DXZ79_RS04935
uniprot id: A0A8D4MZZ3
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS14830
gene id: 1604335:DXZ79_RS14830
uniprot id: A0A386HHI0
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS12605
gene id: 1604335:DXZ79_RS12605
uniprot id: A0A386HFG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS02140
gene id: 1604335:DXZ79_RS02140
uniprot id: A0A386HAS7
names: Function
names: Similarity
messages: Belongs to the UxaA family.
messages: Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).

1604335:DXZ79 RS11890
gene id: 1604335:DXZ79_RS11890
uniprot id: A0A386HEQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS02175
gene id: 1604335:DXZ79_RS02175
uniprot id: A0A386HAI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1604335:DXZ79 RS13830
gene id: 1604335:DXZ79_RS13830
uniprot id: A0A386HG64
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1604335:DXZ79 RS00475
gene id: 1604335:DXZ79_RS00475
uniprot id: A0A386H9K8
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS02765
gene id: 1604335:DXZ79_RS02765
uniprot id: A0A386HAV1
names: Caution
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS15840
gene id: 1604335:DXZ79_RS15840
uniprot id: A0A8D4N3Z8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1604335:DXZ79 RS13530
gene id: 1604335:DXZ79_RS13530
uniprot id: A0A386HGC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1604335:DXZ79 RS13835
gene id: 1604335:DXZ79_RS13835
uniprot id: A0A386HH13
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1604335:DXZ79 RS20530
gene id: 1604335:DXZ79_RS20530
uniprot id: A0A386HJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1604335:DXZ79 RS16370
gene id: 1604335:DXZ79_RS16370
uniprot id: A0A386HHR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1604335:DXZ79 RS17420
gene id: 1604335:DXZ79_RS17420
uniprot id: A0A386HIA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1604335:DXZ79 RS18695
gene id: 1604335:DXZ79_RS18695
uniprot id: A0A386HIK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1604335:DXZ79 RS07805
gene id: 1604335:DXZ79_RS07805
uniprot id: A0A386HD71
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

1604335:DXZ79 RS03810
gene id: 1604335:DXZ79_RS03810
uniprot id: A0A386HAV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS17230
gene id: 1604335:DXZ79_RS17230
uniprot id: A0A386HHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1604335:DXZ79 RS04005
gene id: 1604335:DXZ79_RS04005
uniprot id: A0A386HBL8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1604335:DXZ79 RS10825
gene id: 1604335:DXZ79_RS10825
uniprot id: A0A386HEJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap.

1604335:DXZ79 RS10560
gene id: 1604335:DXZ79_RS10560
uniprot id: A0A386HE31
names: Similarity
messages: Belongs to the DDAH family.

1604335:DXZ79 RS14915
gene id: 1604335:DXZ79_RS14915
uniprot id: A0A386HGW1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1604335:DXZ79 RS12335
gene id: 1604335:DXZ79_RS12335
uniprot id: A0A386HF19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS12655
gene id: 1604335:DXZ79_RS12655
uniprot id: A0A386HFR3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

1604335:DXZ79 RS04890
gene id: 1604335:DXZ79_RS04890
uniprot id: A0A386HBW6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1604335:DXZ79 RS09865
gene id: 1604335:DXZ79_RS09865
uniprot id: A0A386HDW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1604335:DXZ79 RS17810
gene id: 1604335:DXZ79_RS17810
uniprot id: A0A386HIC6
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

1604335:DXZ79 RS02880
gene id: 1604335:DXZ79_RS02880
uniprot id: A0A386HB35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1604335:DXZ79 RS02835
gene id: 1604335:DXZ79_RS02835
uniprot id: A0A386HAW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS12790
gene id: 1604335:DXZ79_RS12790
uniprot id: A0A386HFP6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1604335:DXZ79 RS17270
gene id: 1604335:DXZ79_RS17270
uniprot id: A0A386HHX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

1604335:DXZ79 RS14575
gene id: 1604335:DXZ79_RS14575
uniprot id: A0A386HG33
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1604335:DXZ79 RS19095
gene id: 1604335:DXZ79_RS19095
uniprot id: A0A386HJ96
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1604335:DXZ79 RS15170
gene id: 1604335:DXZ79_RS15170
uniprot id: A0A386HGW7
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1604335:DXZ79 RS12385
gene id: 1604335:DXZ79_RS12385
uniprot id: A0A386HFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

1604335:DXZ79 RS07180
gene id: 1604335:DXZ79_RS07180
uniprot id: A0A386HCT9
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1604335:DXZ79 RS12750
gene id: 1604335:DXZ79_RS12750
uniprot id: A0A386HFJ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS04130
gene id: 1604335:DXZ79_RS04130
uniprot id: A0A386HBR4
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS17410
gene id: 1604335:DXZ79_RS17410
uniprot id: A0A386HHH1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1604335:DXZ79 RS16930
gene id: 1604335:DXZ79_RS16930
uniprot id: A0A386HI13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1604335:DXZ79 RS12910
gene id: 1604335:DXZ79_RS12910
uniprot id: A0A386HFM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1604335:DXZ79 RS13510
gene id: 1604335:DXZ79_RS13510
uniprot id: A0A386HG56
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1604335:DXZ79 RS13250
gene id: 1604335:DXZ79_RS13250
uniprot id: A0A386HFW4
names: Similarity
messages: Belongs to the UPF0352 family.

1604335:DXZ79 RS00130
gene id: 1604335:DXZ79_RS00130
uniprot id: A0A386H9K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS19100
gene id: 1604335:DXZ79_RS19100
uniprot id: A0A386HIV2
names: Similarity
messages: Belongs to the SlyX family.

1604335:DXZ79 RS03980
gene id: 1604335:DXZ79_RS03980
uniprot id: A0A386HAY5
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1604335:DXZ79 RS01355
gene id: 1604335:DXZ79_RS01355
uniprot id: A0A386HA72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

1604335:DXZ79 RS04580
gene id: 1604335:DXZ79_RS04580
uniprot id: A0A386HBG2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1604335:DXZ79 RS20495
gene id: 1604335:DXZ79_RS20495
uniprot id: A0A8E4BMA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1604335:DXZ79 RS07085
gene id: 1604335:DXZ79_RS07085
uniprot id: A0A386HK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1604335:DXZ79 RS15720
gene id: 1604335:DXZ79_RS15720
uniprot id: A0A386HH65
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1604335:DXZ79 RS05370
gene id: 1604335:DXZ79_RS05370
uniprot id: A0A8E4BCX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1604335:DXZ79 RS02520
gene id: 1604335:DXZ79_RS02520
uniprot id: A0A386HA50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

1604335:DXZ79 RS13455
gene id: 1604335:DXZ79_RS13455
uniprot id: A0A386HG11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1604335:DXZ79 RS09100
gene id: 1604335:DXZ79_RS09100
uniprot id: A0A386HDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1604335:DXZ79 RS13335
gene id: 1604335:DXZ79_RS13335
uniprot id: A0A386HFZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

1604335:DXZ79 RS19060
gene id: 1604335:DXZ79_RS19060
uniprot id: A0A386HJM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1604335:DXZ79 RS00200
gene id: 1604335:DXZ79_RS00200
uniprot id: A0A8D4MWN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS18420
gene id: 1604335:DXZ79_RS18420
uniprot id: A0A386HJB6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1604335:DXZ79 RS07875
gene id: 1604335:DXZ79_RS07875
uniprot id: A0A386HDD5
names: Similarity
messages: Belongs to the diol/glycerol dehydratase large subunit family.

1604335:DXZ79 RS05225
gene id: 1604335:DXZ79_RS05225
uniprot id: A0A386HBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1604335:DXZ79 RS13600
gene id: 1604335:DXZ79_RS13600
uniprot id: A0A386HFQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS16685
gene id: 1604335:DXZ79_RS16685
uniprot id: A0A386HH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1604335:DXZ79 RS03370
gene id: 1604335:DXZ79_RS03370
uniprot id: A0A386HB24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1604335:DXZ79 RS11440
gene id: 1604335:DXZ79_RS11440
uniprot id: A0A386HF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS13025
gene id: 1604335:DXZ79_RS13025
uniprot id: A0A386HGM7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1604335:DXZ79 RS10980
gene id: 1604335:DXZ79_RS10980
uniprot id: A0A8E4DEG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1604335:DXZ79 RS00330
gene id: 1604335:DXZ79_RS00330
uniprot id: A0A386H9Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1604335:DXZ79 RS14760
gene id: 1604335:DXZ79_RS14760
uniprot id: A0A386HH42
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. Cof family.
messages: Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).

1604335:DXZ79 RS15685
gene id: 1604335:DXZ79_RS15685
uniprot id: A0A386HGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS18925
gene id: 1604335:DXZ79_RS18925
uniprot id: A0A386HI53
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1604335:DXZ79 RS10800
gene id: 1604335:DXZ79_RS10800
uniprot id: A0A386HEY3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1604335:DXZ79 RS11155
gene id: 1604335:DXZ79_RS11155
uniprot id: A0A386HF91
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1604335:DXZ79 RS18410
gene id: 1604335:DXZ79_RS18410
uniprot id: A0A386HIA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1604335:DXZ79 RS06375
gene id: 1604335:DXZ79_RS06375
uniprot id: A0A386HCW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

1604335:DXZ79 RS19035
gene id: 1604335:DXZ79_RS19035
uniprot id: A0A386HJ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1604335:DXZ79 RS06090
gene id: 1604335:DXZ79_RS06090
uniprot id: A0A386HCB0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1604335:DXZ79 RS08570
gene id: 1604335:DXZ79_RS08570
uniprot id: A0A386HDR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1604335:DXZ79 RS02305
gene id: 1604335:DXZ79_RS02305
uniprot id: A0A8D4MZ63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1604335:DXZ79 RS19895
gene id: 1604335:DXZ79_RS19895
uniprot id: A0A386HIM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS04270
gene id: 1604335:DXZ79_RS04270
uniprot id: A0A386HB39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1604335:DXZ79 RS00245
gene id: 1604335:DXZ79_RS00245
uniprot id: A0A386H9M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS17570
gene id: 1604335:DXZ79_RS17570
uniprot id: A0A386HHJ3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS08335
gene id: 1604335:DXZ79_RS08335
uniprot id: A0A386HDL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

1604335:DXZ79 RS00985
gene id: 1604335:DXZ79_RS00985
uniprot id: A0A386H9Z2
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS03315
gene id: 1604335:DXZ79_RS03315
uniprot id: A0A386HAJ3
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

1604335:DXZ79 RS08725
gene id: 1604335:DXZ79_RS08725
uniprot id: A0A8D4N133
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1604335:DXZ79 RS03350
gene id: 1604335:DXZ79_RS03350
uniprot id: A0A386HB41
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1604335:DXZ79 RS06625
gene id: 1604335:DXZ79_RS06625
uniprot id: A0A8E4BME9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1604335:DXZ79 RS20340
gene id: 1604335:DXZ79_RS20340
uniprot id: A0A386HJC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1604335:DXZ79 RS17555
gene id: 1604335:DXZ79_RS17555
uniprot id: A0A386HI31
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1604335:DXZ79 RS04465
gene id: 1604335:DXZ79_RS04465
uniprot id: A0A386HBN9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1604335:DXZ79 RS12270
gene id: 1604335:DXZ79_RS12270
uniprot id: A0A386HFA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1604335:DXZ79 RS03500
gene id: 1604335:DXZ79_RS03500
uniprot id: A0A8D4MZ19
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS15215
gene id: 1604335:DXZ79_RS15215
uniprot id: A0A386HGV8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1604335:DXZ79 RS05420
gene id: 1604335:DXZ79_RS05420
uniprot id: A0A8D4MY78
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

1604335:DXZ79 RS03710
gene id: 1604335:DXZ79_RS03710
uniprot id: A0A386HAT2
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

1604335:DXZ79 RS11720
gene id: 1604335:DXZ79_RS11720
uniprot id: A0A386HEZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Periplasm

1604335:DXZ79 RS03110
gene id: 1604335:DXZ79_RS03110
uniprot id: A0A8D4SR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1604335:DXZ79 RS06210
gene id: 1604335:DXZ79_RS06210
uniprot id: A0A386HC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS18965
gene id: 1604335:DXZ79_RS18965
uniprot id: A0A386HIY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1604335:DXZ79 RS18980
gene id: 1604335:DXZ79_RS18980
uniprot id: A0A386HIW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1604335:DXZ79 RS05880
gene id: 1604335:DXZ79_RS05880
uniprot id: A0A386HCN0
names: Similarity
messages: Belongs to the UPF0178 family.

1604335:DXZ79 RS02485
gene id: 1604335:DXZ79_RS02485
uniprot id: A0A386HAP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1604335:DXZ79 RS16945
gene id: 1604335:DXZ79_RS16945
uniprot id: A0A386HHR9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1604335:DXZ79 RS12115
gene id: 1604335:DXZ79_RS12115
uniprot id: A0A386HFJ0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1604335:DXZ79 RS06760
gene id: 1604335:DXZ79_RS06760
uniprot id: A0A386HCP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1604335:DXZ79 RS03705
gene id: 1604335:DXZ79_RS03705
uniprot id: A0A386HAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

1604335:DXZ79 RS20360
gene id: 1604335:DXZ79_RS20360
uniprot id: A0A386HIV5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1604335:DXZ79 RS02410
gene id: 1604335:DXZ79_RS02410
uniprot id: A0A386HA31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1604335:DXZ79 RS17800
gene id: 1604335:DXZ79_RS17800
uniprot id: A0A386HHM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1604335:DXZ79 RS10225
gene id: 1604335:DXZ79_RS10225
uniprot id: A0A386HDY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1604335:DXZ79 RS18665
gene id: 1604335:DXZ79_RS18665
uniprot id: A0A386HIR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

1604335:DXZ79 RS04430
gene id: 1604335:DXZ79_RS04430
uniprot id: A0A386HBH8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1604335:DXZ79 RS13450
gene id: 1604335:DXZ79_RS13450
uniprot id: A0A386HGU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS16425
gene id: 1604335:DXZ79_RS16425
uniprot id: A0A386HH10
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1604335:DXZ79 RS11815
gene id: 1604335:DXZ79_RS11815
uniprot id: A0A386HF85
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11210
gene id: 1604335:DXZ79_RS11210
uniprot id: A0A8D4SS34
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1604335:DXZ79 RS17900
gene id: 1604335:DXZ79_RS17900
uniprot id: A0A386HI87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1604335:DXZ79 RS19370
gene id: 1604335:DXZ79_RS19370
uniprot id: A0A386HJ50
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS16975
gene id: 1604335:DXZ79_RS16975
uniprot id: A0A386HHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS19270
gene id: 1604335:DXZ79_RS19270
uniprot id: A0A386HJ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS08765
gene id: 1604335:DXZ79_RS08765
uniprot id: A0A386HDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1604335:DXZ79 RS14170
gene id: 1604335:DXZ79_RS14170
uniprot id: A0A386HH68
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS17415
gene id: 1604335:DXZ79_RS17415
uniprot id: A0A386HI56
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1604335:DXZ79 RS07680
gene id: 1604335:DXZ79_RS07680
uniprot id: A0A386HCV4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1604335:DXZ79 RS03135
gene id: 1604335:DXZ79_RS03135
uniprot id: A0A8D4MYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LsrG family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).

1604335:DXZ79 RS06075
gene id: 1604335:DXZ79_RS06075
uniprot id: A0A386HC55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1604335:DXZ79 RS05180
gene id: 1604335:DXZ79_RS05180
uniprot id: A0A386HC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1604335:DXZ79 RS14950
gene id: 1604335:DXZ79_RS14950
uniprot id: A0A8D4N649
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1604335:DXZ79 RS07670
gene id: 1604335:DXZ79_RS07670
uniprot id: A0A386HD83
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1604335:DXZ79 RS05205
gene id: 1604335:DXZ79_RS05205
uniprot id: A0A8D4SR33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1604335:DXZ79 RS00215
gene id: 1604335:DXZ79_RS00215
uniprot id: A0A386HIZ5
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1604335:DXZ79 RS06240
gene id: 1604335:DXZ79_RS06240
uniprot id: A0A386HJQ3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS04885
gene id: 1604335:DXZ79_RS04885
uniprot id: A0A386HC23
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1604335:DXZ79 RS16105
gene id: 1604335:DXZ79_RS16105
uniprot id: A0A386HHS1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1604335:DXZ79 RS11550
gene id: 1604335:DXZ79_RS11550
uniprot id: A0A386HEW5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS04165
gene id: 1604335:DXZ79_RS04165
uniprot id: A0A386HBI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1604335:DXZ79 RS09755
gene id: 1604335:DXZ79_RS09755
uniprot id: A0A386HE05
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1604335:DXZ79 RS12220
gene id: 1604335:DXZ79_RS12220
uniprot id: A0A386HFK7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1604335:DXZ79 RS14500
gene id: 1604335:DXZ79_RS14500
uniprot id: A0A386HHC6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1604335:DXZ79 RS14810
gene id: 1604335:DXZ79_RS14810
uniprot id: A0A386HH52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1604335:DXZ79 RS10555
gene id: 1604335:DXZ79_RS10555
uniprot id: A0A8E3ZHT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1604335:DXZ79 RS02240
gene id: 1604335:DXZ79_RS02240
uniprot id: A0A386HA22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

1604335:DXZ79 RS00910
gene id: 1604335:DXZ79_RS00910
uniprot id: A0A386HA23
names: Similarity
messages: Belongs to the thioredoxin family.

1604335:DXZ79 RS08425
gene id: 1604335:DXZ79_RS08425
uniprot id: A0A386HDM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1604335:DXZ79 RS20220
gene id: 1604335:DXZ79_RS20220
uniprot id: A0A386HJD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1604335:DXZ79 RS12055
gene id: 1604335:DXZ79_RS12055
uniprot id: A0A386HF63
names: Subcellular Location Annotation
messages: Cell outer membrane

1604335:DXZ79 RS08840
gene id: 1604335:DXZ79_RS08840
uniprot id: A0A8D4N411
names: Function
names: Similarity
messages: Belongs to the EfeM/EfeO family.
messages: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.

1604335:DXZ79 RS01650
gene id: 1604335:DXZ79_RS01650
uniprot id: A0A386HA90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS13555
gene id: 1604335:DXZ79_RS13555
uniprot id: A0A386HG30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1604335:DXZ79 RS02620
gene id: 1604335:DXZ79_RS02620
uniprot id: A0A386HB37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1604335:DXZ79 RS01675
gene id: 1604335:DXZ79_RS01675
uniprot id: A0A386HAF1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1604335:DXZ79 RS03355
gene id: 1604335:DXZ79_RS03355
uniprot id: A0A386HBD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1604335:DXZ79 RS15205
gene id: 1604335:DXZ79_RS15205
uniprot id: A0A386HHC4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1604335:DXZ79 RS04245
gene id: 1604335:DXZ79_RS04245
uniprot id: A0A386HBA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.

1604335:DXZ79 RS08925
gene id: 1604335:DXZ79_RS08925
uniprot id: A0A8D4N5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gtrA family.
messages: Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane.
messages: Membrane

1604335:DXZ79 RS18865
gene id: 1604335:DXZ79_RS18865
uniprot id: A0A386HKE9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1604335:DXZ79 RS19600
gene id: 1604335:DXZ79_RS19600
uniprot id: A0A386HJ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1604335:DXZ79 RS14985
gene id: 1604335:DXZ79_RS14985
uniprot id: A0A386HKX1
names: Function
names: Similarity
messages: Belongs to the AcpH family.
messages: Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.

1604335:DXZ79 RS15025
gene id: 1604335:DXZ79_RS15025
uniprot id: A0A386HGB4
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1604335:DXZ79 RS13540
gene id: 1604335:DXZ79_RS13540
uniprot id: A0A386HFP2
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS01070
gene id: 1604335:DXZ79_RS01070
uniprot id: A0A8D4SQE7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1604335:DXZ79 RS04685
gene id: 1604335:DXZ79_RS04685
uniprot id: A0A8D4N4B8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1604335:DXZ79 RS18520
gene id: 1604335:DXZ79_RS18520
uniprot id: A0A8D4SRS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

1604335:DXZ79 RS10200
gene id: 1604335:DXZ79_RS10200
uniprot id: A0A386HEG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

1604335:DXZ79 RS09375
gene id: 1604335:DXZ79_RS09375
uniprot id: A0A386HE58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1604335:DXZ79 RS10410
gene id: 1604335:DXZ79_RS10410
uniprot id: A0A386HE60
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1604335:DXZ79 RS16995
gene id: 1604335:DXZ79_RS16995
uniprot id: A0A386HHS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1604335:DXZ79 RS00335
gene id: 1604335:DXZ79_RS00335
uniprot id: A0A386H9Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1604335:DXZ79 RS15255
gene id: 1604335:DXZ79_RS15255
uniprot id: A0A386HHD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1604335:DXZ79 RS08480
gene id: 1604335:DXZ79_RS08480
uniprot id: A0A386HDR7
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS20140
gene id: 1604335:DXZ79_RS20140
uniprot id: A0A386HIQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

1604335:DXZ79 RS15670
gene id: 1604335:DXZ79_RS15670
uniprot id: A0A386HH56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS06185
gene id: 1604335:DXZ79_RS06185
uniprot id: A0A386HCF2
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

1604335:DXZ79 RS11185
gene id: 1604335:DXZ79_RS11185
uniprot id: A0A386HF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1604335:DXZ79 RS05865
gene id: 1604335:DXZ79_RS05865
uniprot id: A0A386HCQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

1604335:DXZ79 RS03550
gene id: 1604335:DXZ79_RS03550
uniprot id: A0A386HAP9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1604335:DXZ79 RS10235
gene id: 1604335:DXZ79_RS10235
uniprot id: A0A386HEK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1604335:DXZ79 RS00270
gene id: 1604335:DXZ79_RS00270
uniprot id: A0A386H9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1604335:DXZ79 RS02630
gene id: 1604335:DXZ79_RS02630
uniprot id: A0A386HAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1604335:DXZ79 RS12185
gene id: 1604335:DXZ79_RS12185
uniprot id: A0A386HFK0
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS10435
gene id: 1604335:DXZ79_RS10435
uniprot id: A0A386HE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1604335:DXZ79 RS18990
gene id: 1604335:DXZ79_RS18990
uniprot id: A0A386HJ72
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1604335:DXZ79 RS07105
gene id: 1604335:DXZ79_RS07105
uniprot id: A0A386HCY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0194 family.
messages: Periplasm

1604335:DXZ79 RS19000
gene id: 1604335:DXZ79_RS19000
uniprot id: A0A386HIP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1604335:DXZ79 RS04085
gene id: 1604335:DXZ79_RS04085
uniprot id: A0A386HBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1604335:DXZ79 RS03820
gene id: 1604335:DXZ79_RS03820
uniprot id: A0A386HBK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1604335:DXZ79 RS06960
gene id: 1604335:DXZ79_RS06960
uniprot id: A0A386HD48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS01660
gene id: 1604335:DXZ79_RS01660
uniprot id: A0A386H9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS09680
gene id: 1604335:DXZ79_RS09680
uniprot id: A0A386HEF7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

1604335:DXZ79 RS05130
gene id: 1604335:DXZ79_RS05130
uniprot id: A0A386HCC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1604335:DXZ79 RS09465
gene id: 1604335:DXZ79_RS09465
uniprot id: A0A386HEB8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1604335:DXZ79 RS11950
gene id: 1604335:DXZ79_RS11950
uniprot id: A0A386HER1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HdeB family.
messages: Periplasm
messages: Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.

1604335:DXZ79 RS07595
gene id: 1604335:DXZ79_RS07595
uniprot id: A0A386HCP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1604335:DXZ79 RS07655
gene id: 1604335:DXZ79_RS07655
uniprot id: A0A386HCQ0
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1604335:DXZ79 RS11240
gene id: 1604335:DXZ79_RS11240
uniprot id: A0A386HES0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
messages: Cytoplasm
messages: In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Monomer.

1604335:DXZ79 RS13630
gene id: 1604335:DXZ79_RS13630
uniprot id: A0A386HG76
names: Similarity
messages: Belongs to the UPF0304 family.

1604335:DXZ79 RS10565
gene id: 1604335:DXZ79_RS10565
uniprot id: A0A386HE94
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1604335:DXZ79 RS08865
gene id: 1604335:DXZ79_RS08865
uniprot id: A0A386HDV6
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1604335:DXZ79 RS06805
gene id: 1604335:DXZ79_RS06805
uniprot id: A0A386HCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1604335:DXZ79 RS08715
gene id: 1604335:DXZ79_RS08715
uniprot id: A0A386HE00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1604335:DXZ79 RS03840
gene id: 1604335:DXZ79_RS03840
uniprot id: A0A386HB15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1604335:DXZ79 RS07830
gene id: 1604335:DXZ79_RS07830
uniprot id: A0A386HCT2
names: Similarity
messages: Belongs to the CcmL/EutN family.

1604335:DXZ79 RS06040
gene id: 1604335:DXZ79_RS06040
uniprot id: A0A386HCT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS07675
gene id: 1604335:DXZ79_RS07675
uniprot id: A0A386HDJ9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

1604335:DXZ79 RS14030
gene id: 1604335:DXZ79_RS14030
uniprot id: A0A386HGS2
names: Similarity
messages: Belongs to the MlaA family.

1604335:DXZ79 RS07955
gene id: 1604335:DXZ79_RS07955
uniprot id: A0A386HDP4
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

1604335:DXZ79 RS01120
gene id: 1604335:DXZ79_RS01120
uniprot id: A0A386HAC0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1604335:DXZ79 RS07555
gene id: 1604335:DXZ79_RS07555
uniprot id: A0A386HDB0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

1604335:DXZ79 RS14705
gene id: 1604335:DXZ79_RS14705
uniprot id: A0A386HGM2
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1604335:DXZ79 RS07375
gene id: 1604335:DXZ79_RS07375
uniprot id: A0A386HD27
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1604335:DXZ79 RS05000
gene id: 1604335:DXZ79_RS05000
uniprot id: A0A386HBY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1604335:DXZ79 RS12815
gene id: 1604335:DXZ79_RS12815
uniprot id: A0A386HF97
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1604335:DXZ79 RS12095
gene id: 1604335:DXZ79_RS12095
uniprot id: A0A8D4N3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1604335:DXZ79 RS04905
gene id: 1604335:DXZ79_RS04905
uniprot id: A0A386HBV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS05725
gene id: 1604335:DXZ79_RS05725
uniprot id: A0A386HCA2
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS07780
gene id: 1604335:DXZ79_RS07780
uniprot id: A0A386HCR9
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1604335:DXZ79 RS12700
gene id: 1604335:DXZ79_RS12700
uniprot id: A0A8D4SQU6
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS17600
gene id: 1604335:DXZ79_RS17600
uniprot id: A0A386HIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1604335:DXZ79 RS02460
gene id: 1604335:DXZ79_RS02460
uniprot id: A0A386HA40
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11265
gene id: 1604335:DXZ79_RS11265
uniprot id: A0A8D4SQL7
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

1604335:DXZ79 RS18915
gene id: 1604335:DXZ79_RS18915
uniprot id: A0A386HIX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1604335:DXZ79 RS10530
gene id: 1604335:DXZ79_RS10530
uniprot id: A0A386HE77
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1604335:DXZ79 RS08935
gene id: 1604335:DXZ79_RS08935
uniprot id: A0A386HDY6
names: Similarity
messages: Belongs to the DinB family.

1604335:DXZ79 RS16250
gene id: 1604335:DXZ79_RS16250
uniprot id: A0A386HGY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1604335:DXZ79 RS07000
gene id: 1604335:DXZ79_RS07000
uniprot id: A0A8D4N2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1604335:DXZ79 RS00705
gene id: 1604335:DXZ79_RS00705
uniprot id: A0A386H9P7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS02325
gene id: 1604335:DXZ79_RS02325
uniprot id: A0A386HAS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1604335:DXZ79 RS03480
gene id: 1604335:DXZ79_RS03480
uniprot id: A0A386HB44
names: Similarity
messages: Belongs to the UPF0246 family.

1604335:DXZ79 RS07990
gene id: 1604335:DXZ79_RS07990
uniprot id: A0A386HDF6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1604335:DXZ79 RS04320
gene id: 1604335:DXZ79_RS04320
uniprot id: A0A386HBJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1604335:DXZ79 RS14200
gene id: 1604335:DXZ79_RS14200
uniprot id: A0A386HGI6
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11295
gene id: 1604335:DXZ79_RS11295
uniprot id: A0A386HJW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1604335:DXZ79 RS14805
gene id: 1604335:DXZ79_RS14805
uniprot id: A0A386HGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1604335:DXZ79 RS08340
gene id: 1604335:DXZ79_RS08340
uniprot id: A0A386HD30
names: Subcellular Location Annotation
messages: Cell outer membrane

1604335:DXZ79 RS07885
gene id: 1604335:DXZ79_RS07885
uniprot id: A0A386HCU0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

1604335:DXZ79 RS19115
gene id: 1604335:DXZ79_RS19115
uniprot id: A0A386HJM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

1604335:DXZ79 RS08670
gene id: 1604335:DXZ79_RS08670
uniprot id: A0A386HE45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1604335:DXZ79 RS07315
gene id: 1604335:DXZ79_RS07315
uniprot id: A0A386HCV8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1604335:DXZ79 RS13725
gene id: 1604335:DXZ79_RS13725
uniprot id: A0A386HGZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

1604335:DXZ79 RS18720
gene id: 1604335:DXZ79_RS18720
uniprot id: A0A386HIY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1604335:DXZ79 RS11060
gene id: 1604335:DXZ79_RS11060
uniprot id: A0A8D4N4V4
names: Similarity
messages: Belongs to the peptidase C40 family.

1604335:DXZ79 RS18710
gene id: 1604335:DXZ79_RS18710
uniprot id: A0A386HI18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1604335:DXZ79 RS07985
gene id: 1604335:DXZ79_RS07985
uniprot id: A0A8E4BME3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1604335:DXZ79 RS12230
gene id: 1604335:DXZ79_RS12230
uniprot id: A0A8D4N269
names: Similarity
messages: Belongs to the fabD family.

1604335:DXZ79 RS16415
gene id: 1604335:DXZ79_RS16415
uniprot id: A0A8D4SRS7
names: Function
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1604335:DXZ79 RS15555
gene id: 1604335:DXZ79_RS15555
uniprot id: A0A386HGM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1604335:DXZ79 RS14935
gene id: 1604335:DXZ79_RS14935
uniprot id: A0A386HGR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1604335:DXZ79 RS10420
gene id: 1604335:DXZ79_RS10420
uniprot id: A0A8D4SRZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.

1604335:DXZ79 RS05490
gene id: 1604335:DXZ79_RS05490
uniprot id: A0A8D4N366
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1604335:DXZ79 RS09130
gene id: 1604335:DXZ79_RS09130
uniprot id: A0A8D4N5S0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS19515
gene id: 1604335:DXZ79_RS19515
uniprot id: A0A386HIY7
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS06945
gene id: 1604335:DXZ79_RS06945
uniprot id: A0A386HD75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1604335:DXZ79 RS02655
gene id: 1604335:DXZ79_RS02655
uniprot id: A0A386HAY9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

1604335:DXZ79 RS02405
gene id: 1604335:DXZ79_RS02405
uniprot id: A0A386HAM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

1604335:DXZ79 RS15295
gene id: 1604335:DXZ79_RS15295
uniprot id: A0A386HH35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1604335:DXZ79 RS20540
gene id: 1604335:DXZ79_RS20540
uniprot id: A0A386HJG4
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS14600
gene id: 1604335:DXZ79_RS14600
uniprot id: A0A386HGK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS03440
gene id: 1604335:DXZ79_RS03440
uniprot id: A0A386HB53
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS19065
gene id: 1604335:DXZ79_RS19065
uniprot id: A0A386HIR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1604335:DXZ79 RS13860
gene id: 1604335:DXZ79_RS13860
uniprot id: A0A8D4N237
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1604335:DXZ79 RS20380
gene id: 1604335:DXZ79_RS20380
uniprot id: A0A386HJG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

1604335:DXZ79 RS13110
gene id: 1604335:DXZ79_RS13110
uniprot id: A0A386HG07
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS00190
gene id: 1604335:DXZ79_RS00190
uniprot id: A0A386H9L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS00815
gene id: 1604335:DXZ79_RS00815
uniprot id: A0A8D4N0B5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1604335:DXZ79 RS05495
gene id: 1604335:DXZ79_RS05495
uniprot id: A0A386HBS2
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1604335:DXZ79 RS03680
gene id: 1604335:DXZ79_RS03680
uniprot id: A0A386HBA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

1604335:DXZ79 RS14570
gene id: 1604335:DXZ79_RS14570
uniprot id: A0A8D4N5G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1604335:DXZ79 RS07920
gene id: 1604335:DXZ79_RS07920
uniprot id: A0A386HDQ5
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1604335:DXZ79 RS09340
gene id: 1604335:DXZ79_RS09340
uniprot id: A0A386HE44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

1604335:DXZ79 RS06725
gene id: 1604335:DXZ79_RS06725
uniprot id: A0A386HCR4
names: Similarity
messages: Belongs to the citrate synthase family.

1604335:DXZ79 RS11310
gene id: 1604335:DXZ79_RS11310
uniprot id: A0A386HEK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1604335:DXZ79 RS12760
gene id: 1604335:DXZ79_RS12760
uniprot id: A0A386HF60
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1604335:DXZ79 RS19905
gene id: 1604335:DXZ79_RS19905
uniprot id: A0A386HJC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1604335:DXZ79 RS08250
gene id: 1604335:DXZ79_RS08250
uniprot id: A0A386HDJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS00620
gene id: 1604335:DXZ79_RS00620
uniprot id: A0A386H9Y4
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1604335:DXZ79 RS09530
gene id: 1604335:DXZ79_RS09530
uniprot id: A0A386HEL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS19455
gene id: 1604335:DXZ79_RS19455
uniprot id: A0A386HJ08
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1604335:DXZ79 RS05145
gene id: 1604335:DXZ79_RS05145
uniprot id: A0A386HC82
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

1604335:DXZ79 RS14160
gene id: 1604335:DXZ79_RS14160
uniprot id: A0A386HFW9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1604335:DXZ79 RS05780
gene id: 1604335:DXZ79_RS05780
uniprot id: A0A386HC66
names: Similarity
messages: Belongs to the ArsC family.

1604335:DXZ79 RS17790
gene id: 1604335:DXZ79_RS17790
uniprot id: A0A386HK43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

1604335:DXZ79 RS03050
gene id: 1604335:DXZ79_RS03050
uniprot id: A0A8D4MXI8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1604335:DXZ79 RS02415
gene id: 1604335:DXZ79_RS02415
uniprot id: A0A386HA49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1604335:DXZ79 RS04095
gene id: 1604335:DXZ79_RS04095
uniprot id: A0A386HAZ9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1604335:DXZ79 RS01435
gene id: 1604335:DXZ79_RS01435
uniprot id: A0A386H9V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1604335:DXZ79 RS09830
gene id: 1604335:DXZ79_RS09830
uniprot id: A0A386HDS3
names: Similarity
messages: Belongs to the UPF0225 family.

1604335:DXZ79 RS08855
gene id: 1604335:DXZ79_RS08855
uniprot id: A0A386HDA7
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11130
gene id: 1604335:DXZ79_RS11130
uniprot id: A0A386HF24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

1604335:DXZ79 RS01505
gene id: 1604335:DXZ79_RS01505
uniprot id: A0A386HAC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS20370
gene id: 1604335:DXZ79_RS20370
uniprot id: A0A386HJR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1604335:DXZ79 RS01425
gene id: 1604335:DXZ79_RS01425
uniprot id: A0A8E4BMF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1604335:DXZ79 RS13485
gene id: 1604335:DXZ79_RS13485
uniprot id: A0A386HGH3
names: Similarity
messages: Belongs to the UPF0303 family.

1604335:DXZ79 RS12825
gene id: 1604335:DXZ79_RS12825
uniprot id: A0A8D4N5A6
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS15790
gene id: 1604335:DXZ79_RS15790
uniprot id: A0A8D4N6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS15300
gene id: 1604335:DXZ79_RS15300
uniprot id: A0A386HH80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1604335:DXZ79 RS15995
gene id: 1604335:DXZ79_RS15995
uniprot id: A0A8D4SSV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1604335:DXZ79 RS04960
gene id: 1604335:DXZ79_RS04960
uniprot id: A0A386HBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS15610
gene id: 1604335:DXZ79_RS15610
uniprot id: A0A386HH31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1604335:DXZ79 RS11970
gene id: 1604335:DXZ79_RS11970
uniprot id: A0A386HFF7
names: Similarity
messages: Belongs to the YciI family.

1604335:DXZ79 RS07645
gene id: 1604335:DXZ79_RS07645
uniprot id: A0A386HD13
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1604335:DXZ79 RS17630
gene id: 1604335:DXZ79_RS17630
uniprot id: A0A8D4ST49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1604335:DXZ79 RS00965
gene id: 1604335:DXZ79_RS00965
uniprot id: A0A386H9M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

1604335:DXZ79 RS16400
gene id: 1604335:DXZ79_RS16400
uniprot id: A0A386HIB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

1604335:DXZ79 RS01310
gene id: 1604335:DXZ79_RS01310
uniprot id: A0A8D4N140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS19750
gene id: 1604335:DXZ79_RS19750
uniprot id: A0A386HJ26
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1604335:DXZ79 RS13490
gene id: 1604335:DXZ79_RS13490
uniprot id: A0A386HFN3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS15615
gene id: 1604335:DXZ79_RS15615
uniprot id: A0A386HHW9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS13615
gene id: 1604335:DXZ79_RS13615
uniprot id: A0A8E4FZW6
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS13460
gene id: 1604335:DXZ79_RS13460
uniprot id: A0A386HG47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1604335:DXZ79 RS01665
gene id: 1604335:DXZ79_RS01665
uniprot id: A0A386HAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

1604335:DXZ79 RS01500
gene id: 1604335:DXZ79_RS01500
uniprot id: A0A8D4SP07
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

1604335:DXZ79 RS00080
gene id: 1604335:DXZ79_RS00080
uniprot id: A0A386H9P5
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS18000
gene id: 1604335:DXZ79_RS18000
uniprot id: A0A386HI97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1604335:DXZ79 RS05025
gene id: 1604335:DXZ79_RS05025
uniprot id: A0A386HBS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

1604335:DXZ79 RS03955
gene id: 1604335:DXZ79_RS03955
uniprot id: A0A386HBF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1604335:DXZ79 RS12950
gene id: 1604335:DXZ79_RS12950
uniprot id: A0A386HFE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1604335:DXZ79 RS05085
gene id: 1604335:DXZ79_RS05085
uniprot id: A0A386HBZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YdjC deacetylase family. ChbG subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.

1604335:DXZ79 RS00725
gene id: 1604335:DXZ79_RS00725
uniprot id: A0A386HA63
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1604335:DXZ79 RS03805
gene id: 1604335:DXZ79_RS03805
uniprot id: A0A8D4N012
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1604335:DXZ79 RS08625
gene id: 1604335:DXZ79_RS08625
uniprot id: A0A386HD77
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1604335:DXZ79 RS00855
gene id: 1604335:DXZ79_RS00855
uniprot id: A0A386HA87
names: Similarity
messages: Belongs to the phage antitermination Q type 1 family.

1604335:DXZ79 RS06745
gene id: 1604335:DXZ79_RS06745
uniprot id: A0A386HCT4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1604335:DXZ79 RS04570
gene id: 1604335:DXZ79_RS04570
uniprot id: A0A386HBW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1604335:DXZ79 RS07975
gene id: 1604335:DXZ79_RS07975
uniprot id: A0A386HDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1604335:DXZ79 RS16800
gene id: 1604335:DXZ79_RS16800
uniprot id: A0A386HHN9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1604335:DXZ79 RS15325
gene id: 1604335:DXZ79_RS15325
uniprot id: A0A386HH02
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1604335:DXZ79 RS08400
gene id: 1604335:DXZ79_RS08400
uniprot id: A0A386HD40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1604335:DXZ79 RS18430
gene id: 1604335:DXZ79_RS18430
uniprot id: A0A386HIQ4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1604335:DXZ79 RS13580
gene id: 1604335:DXZ79_RS13580
uniprot id: A0A386HFK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1604335:DXZ79 RS11140
gene id: 1604335:DXZ79_RS11140
uniprot id: A0A386HEH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

1604335:DXZ79 RS15240
gene id: 1604335:DXZ79_RS15240
uniprot id: A0A386HGF1
names: Similarity
messages: Belongs to the RutC family.

1604335:DXZ79 RS02490
gene id: 1604335:DXZ79_RS02490
uniprot id: A0A386HAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1604335:DXZ79 RS05200
gene id: 1604335:DXZ79_RS05200
uniprot id: A0A386HBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1604335:DXZ79 RS06570
gene id: 1604335:DXZ79_RS06570
uniprot id: A0A386HC80
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS04505
gene id: 1604335:DXZ79_RS04505
uniprot id: A0A386HB69
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS06645
gene id: 1604335:DXZ79_RS06645
uniprot id: A0A386HD34
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS19435
gene id: 1604335:DXZ79_RS19435
uniprot id: A0A386HIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1604335:DXZ79 RS13810
gene id: 1604335:DXZ79_RS13810
uniprot id: A0A8D4SNS3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS17985
gene id: 1604335:DXZ79_RS17985
uniprot id: A0A8D4STF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1604335:DXZ79 RS12690
gene id: 1604335:DXZ79_RS12690
uniprot id: A0A386HFM8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1604335:DXZ79 RS15350
gene id: 1604335:DXZ79_RS15350
uniprot id: A0A386HH89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1604335:DXZ79 RS15605
gene id: 1604335:DXZ79_RS15605
uniprot id: A0A386HGN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

1604335:DXZ79 RS09540
gene id: 1604335:DXZ79_RS09540
uniprot id: A0A8D4N4E9
names: Function
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Involved in the high-affinity zinc uptake transport system.

1604335:DXZ79 RS04830
gene id: 1604335:DXZ79_RS04830
uniprot id: A0A8D4SM88
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1604335:DXZ79 RS19745
gene id: 1604335:DXZ79_RS19745
uniprot id: A0A386HJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1604335:DXZ79 RS07605
gene id: 1604335:DXZ79_RS07605
uniprot id: A0A386HDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1604335:DXZ79 RS19240
gene id: 1604335:DXZ79_RS19240
uniprot id: A0A386HIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS15500
gene id: 1604335:DXZ79_RS15500
uniprot id: A0A8D4N5T7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1604335:DXZ79 RS19735
gene id: 1604335:DXZ79_RS19735
uniprot id: A0A8E3ZHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

1604335:DXZ79 RS12410
gene id: 1604335:DXZ79_RS12410
uniprot id: A0A8D4N2U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1604335:DXZ79 RS00605
gene id: 1604335:DXZ79_RS00605
uniprot id: A0A386H9E2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1604335:DXZ79 RS11830
gene id: 1604335:DXZ79_RS11830
uniprot id: A0A386HFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1604335:DXZ79 RS00455
gene id: 1604335:DXZ79_RS00455
uniprot id: A0A386H9F2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1604335:DXZ79 RS18705
gene id: 1604335:DXZ79_RS18705
uniprot id: A0A386HI35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1604335:DXZ79 RS06465
gene id: 1604335:DXZ79_RS06465
uniprot id: A0A386HCC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS05385
gene id: 1604335:DXZ79_RS05385
uniprot id: A0A386HBQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

1604335:DXZ79 RS15575
gene id: 1604335:DXZ79_RS15575
uniprot id: A0A386HH87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1604335:DXZ79 RS17345
gene id: 1604335:DXZ79_RS17345
uniprot id: A0A386HHF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1604335:DXZ79 RS14775
gene id: 1604335:DXZ79_RS14775
uniprot id: A0A386HHH3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1604335:DXZ79 RS00445
gene id: 1604335:DXZ79_RS00445
uniprot id: A0A386H9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1604335:DXZ79 RS12330
gene id: 1604335:DXZ79_RS12330
uniprot id: A0A386HEY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1604335:DXZ79 RS09335
gene id: 1604335:DXZ79_RS09335
uniprot id: A0A386HDI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1604335:DXZ79 RS07525
gene id: 1604335:DXZ79_RS07525
uniprot id: A0A386HD17
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11320
gene id: 1604335:DXZ79_RS11320
uniprot id: A0A386HF88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1604335:DXZ79 RS04160
gene id: 1604335:DXZ79_RS04160
uniprot id: A0A8D4MZ97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

1604335:DXZ79 RS20145
gene id: 1604335:DXZ79_RS20145
uniprot id: A0A386HJG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

1604335:DXZ79 RS12530
gene id: 1604335:DXZ79_RS12530
uniprot id: A0A386HF57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1604335:DXZ79 RS11430
gene id: 1604335:DXZ79_RS11430
uniprot id: A0A8E3ZHT3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1604335:DXZ79 RS06420
gene id: 1604335:DXZ79_RS06420
uniprot id: A0A386HCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1604335:DXZ79 RS01160
gene id: 1604335:DXZ79_RS01160
uniprot id: A0A386H9I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

1604335:DXZ79 RS07265
gene id: 1604335:DXZ79_RS07265
uniprot id: A0A8D4N0L7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1604335:DXZ79 RS00430
gene id: 1604335:DXZ79_RS00430
uniprot id: A0A386H982
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1604335:DXZ79 RS13705
gene id: 1604335:DXZ79_RS13705
uniprot id: A0A386HGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1604335:DXZ79 RS06295
gene id: 1604335:DXZ79_RS06295
uniprot id: A0A386HCX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1604335:DXZ79 RS02560
gene id: 1604335:DXZ79_RS02560
uniprot id: A0A8E4BMB5
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS09875
gene id: 1604335:DXZ79_RS09875
uniprot id: A0A386HES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS19590
gene id: 1604335:DXZ79_RS19590
uniprot id: A0A386HIH9
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

1604335:DXZ79 RS00240
gene id: 1604335:DXZ79_RS00240
uniprot id: A0A8D4SQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1604335:DXZ79 RS17845
gene id: 1604335:DXZ79_RS17845
uniprot id: A0A386HIF1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1604335:DXZ79 RS06770
gene id: 1604335:DXZ79_RS06770
uniprot id: A0A386HCN1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1604335:DXZ79 RS02680
gene id: 1604335:DXZ79_RS02680
uniprot id: A0A386HAN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1604335:DXZ79 RS16080
gene id: 1604335:DXZ79_RS16080
uniprot id: A0A386HHI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS10415
gene id: 1604335:DXZ79_RS10415
uniprot id: A0A386HEK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS10375
gene id: 1604335:DXZ79_RS10375
uniprot id: A0A386HEB0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1604335:DXZ79 RS02665
gene id: 1604335:DXZ79_RS02665
uniprot id: A0A386HAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1604335:DXZ79 RS20520
gene id: 1604335:DXZ79_RS20520
uniprot id: A0A386HJN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1604335:DXZ79 RS15055
gene id: 1604335:DXZ79_RS15055
uniprot id: A0A386HGT3
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1604335:DXZ79 RS04555
gene id: 1604335:DXZ79_RS04555
uniprot id: A0A386HB79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS13610
gene id: 1604335:DXZ79_RS13610
uniprot id: A0A386HGX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS03200
gene id: 1604335:DXZ79_RS03200
uniprot id: A0A386HB16
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1604335:DXZ79 RS12575
gene id: 1604335:DXZ79_RS12575
uniprot id: A0A386HFQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1604335:DXZ79 RS16320
gene id: 1604335:DXZ79_RS16320
uniprot id: A0A386HHW7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1604335:DXZ79 RS05045
gene id: 1604335:DXZ79_RS05045
uniprot id: A0A386HBF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1604335:DXZ79 RS13005
gene id: 1604335:DXZ79_RS13005
uniprot id: A0A386HG89
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS08760
gene id: 1604335:DXZ79_RS08760
uniprot id: A0A386HDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliT family.
messages: Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
messages: Homodimer. Interacts with FliD and FlhC.
messages: cytosol

1604335:DXZ79 RS09950
gene id: 1604335:DXZ79_RS09950
uniprot id: A0A8E4BMF3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1604335:DXZ79 RS13475
gene id: 1604335:DXZ79_RS13475
uniprot id: A0A8D4SNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS02190
gene id: 1604335:DXZ79_RS02190
uniprot id: A0A386HAU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1604335:DXZ79 RS15150
gene id: 1604335:DXZ79_RS15150
uniprot id: A0A8D4SRK3
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

1604335:DXZ79 RS02170
gene id: 1604335:DXZ79_RS02170
uniprot id: A0A386HAD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

1604335:DXZ79 RS17575
gene id: 1604335:DXZ79_RS17575
uniprot id: A0A386HI88
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family.
messages: Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.

1604335:DXZ79 RS06755
gene id: 1604335:DXZ79_RS06755
uniprot id: A0A386HCG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1604335:DXZ79 RS11940
gene id: 1604335:DXZ79_RS11940
uniprot id: A0A386HFF4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1604335:DXZ79 RS05645
gene id: 1604335:DXZ79_RS05645
uniprot id: A0A386HBZ7
names: Similarity
messages: Belongs to the GppA/Ppx family.

1604335:DXZ79 RS12730
gene id: 1604335:DXZ79_RS12730
uniprot id: A0A8D4N2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS17675
gene id: 1604335:DXZ79_RS17675
uniprot id: A0A386HHK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

1604335:DXZ79 RS16310
gene id: 1604335:DXZ79_RS16310
uniprot id: A0A386HHL8
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1604335:DXZ79 RS17865
gene id: 1604335:DXZ79_RS17865
uniprot id: A0A386HIH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1604335:DXZ79 RS17035
gene id: 1604335:DXZ79_RS17035
uniprot id: A0A386HI34
names: Similarity
messages: Belongs to the type III secretion exporter family.

1604335:DXZ79 RS12550
gene id: 1604335:DXZ79_RS12550
uniprot id: A0A386HFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

1604335:DXZ79 RS12565
gene id: 1604335:DXZ79_RS12565
uniprot id: A0A8D4N4T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

1604335:DXZ79 RS08105
gene id: 1604335:DXZ79_RS08105
uniprot id: A0A386HD87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1604335:DXZ79 RS02575
gene id: 1604335:DXZ79_RS02575
uniprot id: A0A386HA61
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1604335:DXZ79 RS16165
gene id: 1604335:DXZ79_RS16165
uniprot id: A0A386HHD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1604335:DXZ79 RS04335
gene id: 1604335:DXZ79_RS04335
uniprot id: A0A386HBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1604335:DXZ79 RS12710
gene id: 1604335:DXZ79_RS12710
uniprot id: A0A386HF49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1604335:DXZ79 RS11715
gene id: 1604335:DXZ79_RS11715
uniprot id: A0A386HFW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

1604335:DXZ79 RS11870
gene id: 1604335:DXZ79_RS11870
uniprot id: A0A386HFZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

1604335:DXZ79 RS14540
gene id: 1604335:DXZ79_RS14540
uniprot id: A0A386HH04
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS03795
gene id: 1604335:DXZ79_RS03795
uniprot id: A0A386HB62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1604335:DXZ79 RS19170
gene id: 1604335:DXZ79_RS19170
uniprot id: A0A8E4DEB8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1604335:DXZ79 RS18210
gene id: 1604335:DXZ79_RS18210
uniprot id: A0A386HID4
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

1604335:DXZ79 RS01025
gene id: 1604335:DXZ79_RS01025
uniprot id: A0A386HA19
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1604335:DXZ79 RS09655
gene id: 1604335:DXZ79_RS09655
uniprot id: A0A386HEA7
names: Similarity
messages: Belongs to the UPF0260 family.

1604335:DXZ79 RS17595
gene id: 1604335:DXZ79_RS17595
uniprot id: A0A8D4N7S0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1604335:DXZ79 RS14770
gene id: 1604335:DXZ79_RS14770
uniprot id: A0A386HGN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1604335:DXZ79 RS20150
gene id: 1604335:DXZ79_RS20150
uniprot id: A0A386HJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1604335:DXZ79 RS13865
gene id: 1604335:DXZ79_RS13865
uniprot id: A0A8D4N5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1604335:DXZ79 RS13745
gene id: 1604335:DXZ79_RS13745
uniprot id: A0A386HFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS15805
gene id: 1604335:DXZ79_RS15805
uniprot id: A0A386HHD5
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1604335:DXZ79 RS13465
gene id: 1604335:DXZ79_RS13465
uniprot id: A0A386HFH3
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

1604335:DXZ79 RS03630
gene id: 1604335:DXZ79_RS03630
uniprot id: A0A386HBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1604335:DXZ79 RS12705
gene id: 1604335:DXZ79_RS12705
uniprot id: A0A386HFR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1604335:DXZ79 RS14880
gene id: 1604335:DXZ79_RS14880
uniprot id: A0A8D4N149
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1604335:DXZ79 RS09190
gene id: 1604335:DXZ79_RS09190
uniprot id: A0A386HE04
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS09675
gene id: 1604335:DXZ79_RS09675
uniprot id: A0A386HEA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1604335:DXZ79 RS06105
gene id: 1604335:DXZ79_RS06105
uniprot id: A0A386HBY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1604335:DXZ79 RS07325
gene id: 1604335:DXZ79_RS07325
uniprot id: A0A386HCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1604335:DXZ79 RS16670
gene id: 1604335:DXZ79_RS16670
uniprot id: A0A386HIF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1604335:DXZ79 RS19365
gene id: 1604335:DXZ79_RS19365
uniprot id: A0A386HIV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

1604335:DXZ79 RS11765
gene id: 1604335:DXZ79_RS11765
uniprot id: A0A386HFX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1604335:DXZ79 RS05995
gene id: 1604335:DXZ79_RS05995
uniprot id: A0A386HCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1604335:DXZ79 RS04250
gene id: 1604335:DXZ79_RS04250
uniprot id: A0A386HBK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1604335:DXZ79 RS08985
gene id: 1604335:DXZ79_RS08985
uniprot id: A0A386HDY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1604335:DXZ79 RS20295
gene id: 1604335:DXZ79_RS20295
uniprot id: A0A386HJJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Homodimer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to oligomers at high temperatures or high ionic concentrations. The decrease in size of the multimers is accompanied by an increase in chaperone activity.
messages: The N- and C-terminal flexible termini are involved in oligomerization and in the binding of non-native substrate proteins, and are essential for chaperone activity.

1604335:DXZ79 RS15590
gene id: 1604335:DXZ79_RS15590
uniprot id: A0A386HH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1604335:DXZ79 RS14680
gene id: 1604335:DXZ79_RS14680
uniprot id: A0A386HG52
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1604335:DXZ79 RS06410
gene id: 1604335:DXZ79_RS06410
uniprot id: A0A386HCZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1604335:DXZ79 RS04120
gene id: 1604335:DXZ79_RS04120
uniprot id: A0A8D4N230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1604335:DXZ79 RS17145
gene id: 1604335:DXZ79_RS17145
uniprot id: A0A386HI57
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1604335:DXZ79 RS11045
gene id: 1604335:DXZ79_RS11045
uniprot id: A0A386HFD7
names: Similarity
messages: Belongs to the glyoxalase I family.

1604335:DXZ79 RS17385
gene id: 1604335:DXZ79_RS17385
uniprot id: A0A8D4N3S5
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1604335:DXZ79 RS17980
gene id: 1604335:DXZ79_RS17980
uniprot id: A0A386HIF4
names: Similarity
messages: Belongs to the RutC family.

1604335:DXZ79 RS02855
gene id: 1604335:DXZ79_RS02855
uniprot id: A0A386HAU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

1604335:DXZ79 RS01455
gene id: 1604335:DXZ79_RS01455
uniprot id: A0A386HA62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1604335:DXZ79 RS16990
gene id: 1604335:DXZ79_RS16990
uniprot id: A0A386HHE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1604335:DXZ79 RS09690
gene id: 1604335:DXZ79_RS09690
uniprot id: A0A386HE84
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1604335:DXZ79 RS16155
gene id: 1604335:DXZ79_RS16155
uniprot id: A0A386HHT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1604335:DXZ79 RS11805
gene id: 1604335:DXZ79_RS11805
uniprot id: A0A8D4SR22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1604335:DXZ79 RS12085
gene id: 1604335:DXZ79_RS12085
uniprot id: A0A8D4N2Q2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

1604335:DXZ79 RS00155
gene id: 1604335:DXZ79_RS00155
uniprot id: A0A386H9Q5
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

1604335:DXZ79 RS13390
gene id: 1604335:DXZ79_RS13390
uniprot id: A0A386HGT1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1604335:DXZ79 RS19930
gene id: 1604335:DXZ79_RS19930
uniprot id: A0A8E3ZHZ6
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS18790
gene id: 1604335:DXZ79_RS18790
uniprot id: A0A386HI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1604335:DXZ79 RS15640
gene id: 1604335:DXZ79_RS15640
uniprot id: A0A386HHA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1604335:DXZ79 RS01405
gene id: 1604335:DXZ79_RS01405
uniprot id: A0A8D4N153
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1604335:DXZ79 RS16325
gene id: 1604335:DXZ79_RS16325
uniprot id: A0A386HH27
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1604335:DXZ79 RS14870
gene id: 1604335:DXZ79_RS14870
uniprot id: A0A386HH62
names: Similarity
messages: Belongs to the UPF0234 family.

1604335:DXZ79 RS12120
gene id: 1604335:DXZ79_RS12120
uniprot id: A0A386HEU2
names: Similarity
messages: Belongs to the UPF0227 family.

1604335:DXZ79 RS04090
gene id: 1604335:DXZ79_RS04090
uniprot id: A0A8D4N3G3
names: Similarity
messages: Belongs to the SfsA family.

1604335:DXZ79 RS20095
gene id: 1604335:DXZ79_RS20095
uniprot id: A0A386HJL9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1604335:DXZ79 RS16355
gene id: 1604335:DXZ79_RS16355
uniprot id: A0A386HGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1604335:DXZ79 RS15060
gene id: 1604335:DXZ79_RS15060
uniprot id: A0A386HHL4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

1604335:DXZ79 RS04850
gene id: 1604335:DXZ79_RS04850
uniprot id: A0A386HBU2
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

1604335:DXZ79 RS13635
gene id: 1604335:DXZ79_RS13635
uniprot id: A0A386HFL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS09345
gene id: 1604335:DXZ79_RS09345
uniprot id: A0A386HE42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1604335:DXZ79 RS04875
gene id: 1604335:DXZ79_RS04875
uniprot id: A0A386HBG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1604335:DXZ79 RS17300
gene id: 1604335:DXZ79_RS17300
uniprot id: A0A386HI36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1604335:DXZ79 RS18660
gene id: 1604335:DXZ79_RS18660
uniprot id: A0A386HL23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS10100
gene id: 1604335:DXZ79_RS10100
uniprot id: A0A386HEW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1604335:DXZ79 RS01150
gene id: 1604335:DXZ79_RS01150
uniprot id: A0A386H9X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1604335:DXZ79 RS11290
gene id: 1604335:DXZ79_RS11290
uniprot id: A0A386HET0
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

1604335:DXZ79 RS10905
gene id: 1604335:DXZ79_RS10905
uniprot id: A0A8D4SNA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1604335:DXZ79 RS10775
gene id: 1604335:DXZ79_RS10775
uniprot id: A0A386HE68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS10870
gene id: 1604335:DXZ79_RS10870
uniprot id: A0A8E4BJQ0
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS13080
gene id: 1604335:DXZ79_RS13080
uniprot id: A0A386HFU4
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS04670
gene id: 1604335:DXZ79_RS04670
uniprot id: A0A386HBL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1604335:DXZ79 RS18855
gene id: 1604335:DXZ79_RS18855
uniprot id: A0A8D4SRU5
names: Similarity
messages: Belongs to the DprA/Smf family.

1604335:DXZ79 RS01260
gene id: 1604335:DXZ79_RS01260
uniprot id: A0A386H9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS05805
gene id: 1604335:DXZ79_RS05805
uniprot id: A0A386HCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS00560
gene id: 1604335:DXZ79_RS00560
uniprot id: A0A386H9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

1604335:DXZ79 RS16235
gene id: 1604335:DXZ79_RS16235
uniprot id: A0A386HHE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1604335:DXZ79 RS10630
gene id: 1604335:DXZ79_RS10630
uniprot id: A0A386HES3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS15785
gene id: 1604335:DXZ79_RS15785
uniprot id: A0A386HH74
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS13265
gene id: 1604335:DXZ79_RS13265
uniprot id: A0A386HFT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1604335:DXZ79 RS07565
gene id: 1604335:DXZ79_RS07565
uniprot id: A0A386HDH9
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS18940
gene id: 1604335:DXZ79_RS18940
uniprot id: A0A386HJ61
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1604335:DXZ79 RS20365
gene id: 1604335:DXZ79_RS20365
uniprot id: A0A386HJK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1604335:DXZ79 RS00545
gene id: 1604335:DXZ79_RS00545
uniprot id: A0A386H9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1604335:DXZ79 RS16220
gene id: 1604335:DXZ79_RS16220
uniprot id: A0A386HH08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

1604335:DXZ79 RS03490
gene id: 1604335:DXZ79_RS03490
uniprot id: A0A386HAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1604335:DXZ79 RS18080
gene id: 1604335:DXZ79_RS18080
uniprot id: A0A386HHS0
names: Similarity
messages: Belongs to the barstar family.

1604335:DXZ79 RS07600
gene id: 1604335:DXZ79_RS07600
uniprot id: A0A8D4N0Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1604335:DXZ79 RS05135
gene id: 1604335:DXZ79_RS05135
uniprot id: A0A386HBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1604335:DXZ79 RS15865
gene id: 1604335:DXZ79_RS15865
uniprot id: A0A386HHN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS16195
gene id: 1604335:DXZ79_RS16195
uniprot id: A0A386HGX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1604335:DXZ79 RS11810
gene id: 1604335:DXZ79_RS11810
uniprot id: A0A386HEU3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS04435
gene id: 1604335:DXZ79_RS04435
uniprot id: A0A386HBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1604335:DXZ79 RS16775
gene id: 1604335:DXZ79_RS16775
uniprot id: A0A8D4N6K6
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1604335:DXZ79 RS19485
gene id: 1604335:DXZ79_RS19485
uniprot id: A0A386HIG1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1604335:DXZ79 RS04990
gene id: 1604335:DXZ79_RS04990
uniprot id: A0A386HBE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1604335:DXZ79 RS02600
gene id: 1604335:DXZ79_RS02600
uniprot id: A0A386HAE9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1604335:DXZ79 RS19020
gene id: 1604335:DXZ79_RS19020
uniprot id: A0A386HI85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1604335:DXZ79 RS14590
gene id: 1604335:DXZ79_RS14590
uniprot id: A0A386HH14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1604335:DXZ79 RS16955
gene id: 1604335:DXZ79_RS16955
uniprot id: A0A386HHR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1604335:DXZ79 RS01175
gene id: 1604335:DXZ79_RS01175
uniprot id: A0A386HA46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1604335:DXZ79 RS13985
gene id: 1604335:DXZ79_RS13985
uniprot id: A0A386HG92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1604335:DXZ79 RS18950
gene id: 1604335:DXZ79_RS18950
uniprot id: A0A386HIN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1604335:DXZ79 RS01040
gene id: 1604335:DXZ79_RS01040
uniprot id: A0A386HA42
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1604335:DXZ79 RS02545
gene id: 1604335:DXZ79_RS02545
uniprot id: A0A386HAD8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1604335:DXZ79 RS02225
gene id: 1604335:DXZ79_RS02225
uniprot id: A0A386HAE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS20505
gene id: 1604335:DXZ79_RS20505
uniprot id: A0A386HJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1604335:DXZ79 RS18880
gene id: 1604335:DXZ79_RS18880
uniprot id: A0A386HIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1604335:DXZ79 RS12975
gene id: 1604335:DXZ79_RS12975
uniprot id: A0A386HFX0
names: Subunit
messages: Monomer.

1604335:DXZ79 RS19765
gene id: 1604335:DXZ79_RS19765
uniprot id: A0A386HJ24
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1604335:DXZ79 RS05605
gene id: 1604335:DXZ79_RS05605
uniprot id: A0A386HBU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

1604335:DXZ79 RS04705
gene id: 1604335:DXZ79_RS04705
uniprot id: A0A386HBI1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1604335:DXZ79 RS10965
gene id: 1604335:DXZ79_RS10965
uniprot id: A0A8D4N4P7
names: Similarity
messages: Belongs to the GST superfamily.

1604335:DXZ79 RS03695
gene id: 1604335:DXZ79_RS03695
uniprot id: A0A8D4SPC9
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1604335:DXZ79 RS20115
gene id: 1604335:DXZ79_RS20115
uniprot id: A0A386HK38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family.
messages: Cell inner membrane
messages: Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.

1604335:DXZ79 RS03525
gene id: 1604335:DXZ79_RS03525
uniprot id: A0A386HBG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1604335:DXZ79 RS13340
gene id: 1604335:DXZ79_RS13340
uniprot id: A0A386HG27
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1604335:DXZ79 RS07625
gene id: 1604335:DXZ79_RS07625
uniprot id: A0A386HD36
names: Similarity
messages: Belongs to the UPF0053 family.

1604335:DXZ79 RS14685
gene id: 1604335:DXZ79_RS14685
uniprot id: A0A386HGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS18545
gene id: 1604335:DXZ79_RS18545
uniprot id: A0A386HIJ2
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS03190
gene id: 1604335:DXZ79_RS03190
uniprot id: A0A8D4MZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1604335:DXZ79 RS16840
gene id: 1604335:DXZ79_RS16840
uniprot id: A0A386HHA7
names: Similarity
messages: Belongs to the MotB family.

1604335:DXZ79 RS07075
gene id: 1604335:DXZ79_RS07075
uniprot id: A0A386HCS0
names: Similarity
messages: Belongs to the MoaD family.

1604335:DXZ79 RS16190
gene id: 1604335:DXZ79_RS16190
uniprot id: A0A386HGW4
names: Similarity
messages: Belongs to the UPF0149 family.

1604335:DXZ79 RS12635
gene id: 1604335:DXZ79_RS12635
uniprot id: A0A386HF83
names: Similarity
messages: Belongs to the YkuD family.

1604335:DXZ79 RS05850
gene id: 1604335:DXZ79_RS05850
uniprot id: A0A386HBU7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

1604335:DXZ79 RS08780
gene id: 1604335:DXZ79_RS08780
uniprot id: A0A386HDM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1604335:DXZ79 RS17400
gene id: 1604335:DXZ79_RS17400
uniprot id: A0A386HI66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1604335:DXZ79 RS08720
gene id: 1604335:DXZ79_RS08720
uniprot id: A0A386HDD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1604335:DXZ79 RS11985
gene id: 1604335:DXZ79_RS11985
uniprot id: A0A386HEW7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1604335:DXZ79 RS05585
gene id: 1604335:DXZ79_RS05585
uniprot id: A0A386HC59
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

1604335:DXZ79 RS18645
gene id: 1604335:DXZ79_RS18645
uniprot id: A0A386HIT5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1604335:DXZ79 RS20300
gene id: 1604335:DXZ79_RS20300
uniprot id: A0A8E3ZHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

1604335:DXZ79 RS03985
gene id: 1604335:DXZ79_RS03985
uniprot id: A0A386HAY0
names: Similarity
messages: Belongs to the UPF0231 family.

1604335:DXZ79 RS20190
gene id: 1604335:DXZ79_RS20190
uniprot id: A0A386HIS9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1604335:DXZ79 RS01215
gene id: 1604335:DXZ79_RS01215
uniprot id: A0A386H9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1604335:DXZ79 RS13995
gene id: 1604335:DXZ79_RS13995
uniprot id: A0A8D4SSU8
names: Similarity
messages: Belongs to the UPF0115 family.

1604335:DXZ79 RS09965
gene id: 1604335:DXZ79_RS09965
uniprot id: A0A386HEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS04080
gene id: 1604335:DXZ79_RS04080
uniprot id: A0A8D4N2K6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1604335:DXZ79 RS00780
gene id: 1604335:DXZ79_RS00780
uniprot id: A0A8D4N0Y2
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

1604335:DXZ79 RS11345
gene id: 1604335:DXZ79_RS11345
uniprot id: A0A386HFR6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS05380
gene id: 1604335:DXZ79_RS05380
uniprot id: A0A386HC42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

1604335:DXZ79 RS02890
gene id: 1604335:DXZ79_RS02890
uniprot id: A0A386HAX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1604335:DXZ79 RS19505
gene id: 1604335:DXZ79_RS19505
uniprot id: A0A8D4N7L1
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

1604335:DXZ79 RS05890
gene id: 1604335:DXZ79_RS05890
uniprot id: A0A386HCC7
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

1604335:DXZ79 RS02605
gene id: 1604335:DXZ79_RS02605
uniprot id: A0A386HAS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1604335:DXZ79 RS03760
gene id: 1604335:DXZ79_RS03760
uniprot id: A0A386HAT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1604335:DXZ79 RS17360
gene id: 1604335:DXZ79_RS17360
uniprot id: A0A386HI91
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1604335:DXZ79 RS19935
gene id: 1604335:DXZ79_RS19935
uniprot id: A0A386HJ54
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS14210
gene id: 1604335:DXZ79_RS14210
uniprot id: A0A386HGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1604335:DXZ79 RS00280
gene id: 1604335:DXZ79_RS00280
uniprot id: A0A386H9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1604335:DXZ79 RS00135
gene id: 1604335:DXZ79_RS00135
uniprot id: A0A386H938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1604335:DXZ79 RS03725
gene id: 1604335:DXZ79_RS03725
uniprot id: A0A386HBH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1604335:DXZ79 RS06820
gene id: 1604335:DXZ79_RS06820
uniprot id: A0A386HCP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1604335:DXZ79 RS03905
gene id: 1604335:DXZ79_RS03905
uniprot id: A0A386HBM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS03335
gene id: 1604335:DXZ79_RS03335
uniprot id: A0A386HB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

1604335:DXZ79 RS14740
gene id: 1604335:DXZ79_RS14740
uniprot id: A0A386HG63
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS10760
gene id: 1604335:DXZ79_RS10760
uniprot id: A0A386HF84
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1604335:DXZ79 RS09295
gene id: 1604335:DXZ79_RS09295
uniprot id: A0A386HE90
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1604335:DXZ79 RS05040
gene id: 1604335:DXZ79_RS05040
uniprot id: A0A386HJS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1604335:DXZ79 RS07970
gene id: 1604335:DXZ79_RS07970
uniprot id: A0A386HD95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1604335:DXZ79 RS06080
gene id: 1604335:DXZ79_RS06080
uniprot id: A0A8D4N0A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1604335:DXZ79 RS13270
gene id: 1604335:DXZ79_RS13270
uniprot id: A0A386HG19
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS07530
gene id: 1604335:DXZ79_RS07530
uniprot id: A0A8D4SRG7
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS17780
gene id: 1604335:DXZ79_RS17780
uniprot id: A0A386HL09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

1604335:DXZ79 RS04845
gene id: 1604335:DXZ79_RS04845
uniprot id: A0A386HBK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1604335:DXZ79 RS05520
gene id: 1604335:DXZ79_RS05520
uniprot id: A0A386HBY0
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

1604335:DXZ79 RS14920
gene id: 1604335:DXZ79_RS14920
uniprot id: A0A386HH15
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1604335:DXZ79 RS02685
gene id: 1604335:DXZ79_RS02685
uniprot id: A0A386HAR7
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1604335:DXZ79 RS14890
gene id: 1604335:DXZ79_RS14890
uniprot id: A0A386HGR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS03565
gene id: 1604335:DXZ79_RS03565
uniprot id: A0A386HBE4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1604335:DXZ79 RS19290
gene id: 1604335:DXZ79_RS19290
uniprot id: A0A386HJQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

1604335:DXZ79 RS20175
gene id: 1604335:DXZ79_RS20175
uniprot id: A0A8E4DED3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1604335:DXZ79 RS20375
gene id: 1604335:DXZ79_RS20375
uniprot id: A0A386HJW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1604335:DXZ79 RS09430
gene id: 1604335:DXZ79_RS09430
uniprot id: A0A386HEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS00940
gene id: 1604335:DXZ79_RS00940
uniprot id: A0A386H9H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

1604335:DXZ79 RS05650
gene id: 1604335:DXZ79_RS05650
uniprot id: A0A386HC67
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1604335:DXZ79 RS05375
gene id: 1604335:DXZ79_RS05375
uniprot id: A0A386HBY6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1604335:DXZ79 RS17140
gene id: 1604335:DXZ79_RS17140
uniprot id: A0A386HI09
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1604335:DXZ79 RS18140
gene id: 1604335:DXZ79_RS18140
uniprot id: A0A386HII4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1604335:DXZ79 RS15990
gene id: 1604335:DXZ79_RS15990
uniprot id: A0A386HHA0
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS02635
gene id: 1604335:DXZ79_RS02635
uniprot id: A0A386HA75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1604335:DXZ79 RS13715
gene id: 1604335:DXZ79_RS13715
uniprot id: A0A386HFR2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS13845
gene id: 1604335:DXZ79_RS13845
uniprot id: A0A386HGB3
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

1604335:DXZ79 RS16135
gene id: 1604335:DXZ79_RS16135
uniprot id: A0A386HGV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

1604335:DXZ79 RS08005
gene id: 1604335:DXZ79_RS08005
uniprot id: A0A8D4SMR9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1604335:DXZ79 RS19490
gene id: 1604335:DXZ79_RS19490
uniprot id: A0A386HIF6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1604335:DXZ79 RS17920
gene id: 1604335:DXZ79_RS17920
uniprot id: A0A386HIE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1604335:DXZ79 RS06385
gene id: 1604335:DXZ79_RS06385
uniprot id: A0A8D4N3H4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1604335:DXZ79 RS17195
gene id: 1604335:DXZ79_RS17195
uniprot id: A0A386HI20
names: Similarity
messages: Belongs to the GSP E family.

1604335:DXZ79 RS18900
gene id: 1604335:DXZ79_RS18900
uniprot id: A0A386HIM9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1604335:DXZ79 RS04180
gene id: 1604335:DXZ79_RS04180
uniprot id: A0A386HB86
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1604335:DXZ79 RS02310
gene id: 1604335:DXZ79_RS02310
uniprot id: A0A386HAV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1604335:DXZ79 RS12540
gene id: 1604335:DXZ79_RS12540
uniprot id: A0A386HGB8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1604335:DXZ79 RS01390
gene id: 1604335:DXZ79_RS01390
uniprot id: A0A8D4SLP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS18735
gene id: 1604335:DXZ79_RS18735
uniprot id: A0A386HIL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

1604335:DXZ79 RS18725
gene id: 1604335:DXZ79_RS18725
uniprot id: A0A386HJ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1604335:DXZ79 RS17075
gene id: 1604335:DXZ79_RS17075
uniprot id: A0A8E4DFB4
names: Similarity
messages: Belongs to the isochorismate synthase family.

1604335:DXZ79 RS19385
gene id: 1604335:DXZ79_RS19385
uniprot id: A0A386HJ36
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1604335:DXZ79 RS00980
gene id: 1604335:DXZ79_RS00980
uniprot id: A0A386H9T9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

1604335:DXZ79 RS07360
gene id: 1604335:DXZ79_RS07360
uniprot id: A0A386HDE0
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS00465
gene id: 1604335:DXZ79_RS00465
uniprot id: A0A8D4SLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1604335:DXZ79 RS08580
gene id: 1604335:DXZ79_RS08580
uniprot id: A0A386HD59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1604335:DXZ79 RS05480
gene id: 1604335:DXZ79_RS05480
uniprot id: A0A386HCF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS13010
gene id: 1604335:DXZ79_RS13010
uniprot id: A0A386HFF1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1604335:DXZ79 RS03160
gene id: 1604335:DXZ79_RS03160
uniprot id: A0A386HJT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS02215
gene id: 1604335:DXZ79_RS02215
uniprot id: A0A386HAL2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1604335:DXZ79 RS09630
gene id: 1604335:DXZ79_RS09630
uniprot id: A0A386HDT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1604335:DXZ79 RS10090
gene id: 1604335:DXZ79_RS10090
uniprot id: A0A386HE02
names: Similarity
messages: Belongs to the peptidase S49 family.

1604335:DXZ79 RS11690
gene id: 1604335:DXZ79_RS11690
uniprot id: A0A386HFF3
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1604335:DXZ79 RS13675
gene id: 1604335:DXZ79_RS13675
uniprot id: A0A386HG51
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1604335:DXZ79 RS15745
gene id: 1604335:DXZ79_RS15745
uniprot id: A0A386HGN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

1604335:DXZ79 RS03855
gene id: 1604335:DXZ79_RS03855
uniprot id: A0A386HB73
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1604335:DXZ79 RS14505
gene id: 1604335:DXZ79_RS14505
uniprot id: A0A386HGJ7
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS17685
gene id: 1604335:DXZ79_RS17685
uniprot id: A0A386HHL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS00730
gene id: 1604335:DXZ79_RS00730
uniprot id: A0A386H9X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS17850
gene id: 1604335:DXZ79_RS17850
uniprot id: A0A386HHN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1604335:DXZ79 RS18470
gene id: 1604335:DXZ79_RS18470
uniprot id: A0A386HIH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS18375
gene id: 1604335:DXZ79_RS18375
uniprot id: A0A386HIP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS08265
gene id: 1604335:DXZ79_RS08265
uniprot id: A0A386HDD8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
messages: Membrane

1604335:DXZ79 RS06620
gene id: 1604335:DXZ79_RS06620
uniprot id: A0A386HC88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

1604335:DXZ79 RS07705
gene id: 1604335:DXZ79_RS07705
uniprot id: A0A386HDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS08805
gene id: 1604335:DXZ79_RS08805
uniprot id: A0A386HD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS09240
gene id: 1604335:DXZ79_RS09240
uniprot id: A0A386HE12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1604335:DXZ79 RS19460
gene id: 1604335:DXZ79_RS19460
uniprot id: A0A386HIX7
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

1604335:DXZ79 RS15030
gene id: 1604335:DXZ79_RS15030
uniprot id: A0A386HK08
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1604335:DXZ79 RS20490
gene id: 1604335:DXZ79_RS20490
uniprot id: A0A8E4BM75
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS08800
gene id: 1604335:DXZ79_RS08800
uniprot id: A0A386HDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS02735
gene id: 1604335:DXZ79_RS02735
uniprot id: A0A386HAP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS18970
gene id: 1604335:DXZ79_RS18970
uniprot id: A0A386HI75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1604335:DXZ79 RS00805
gene id: 1604335:DXZ79_RS00805
uniprot id: A0A386H9W4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1604335:DXZ79 RS06005
gene id: 1604335:DXZ79_RS06005
uniprot id: A0A386HCE6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS10685
gene id: 1604335:DXZ79_RS10685
uniprot id: A0A386HEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1604335:DXZ79 RS13410
gene id: 1604335:DXZ79_RS13410
uniprot id: A0A386HFG4
names: Similarity
messages: Belongs to the CinA family.

1604335:DXZ79 RS15370
gene id: 1604335:DXZ79_RS15370
uniprot id: A0A386HGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1604335:DXZ79 RS01185
gene id: 1604335:DXZ79_RS01185
uniprot id: A0A386H9S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1604335:DXZ79 RS06775
gene id: 1604335:DXZ79_RS06775
uniprot id: A0A386HCS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS13565
gene id: 1604335:DXZ79_RS13565
uniprot id: A0A386HK80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1604335:DXZ79 RS09805
gene id: 1604335:DXZ79_RS09805
uniprot id: A0A8E4BMT4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1604335:DXZ79 RS19465
gene id: 1604335:DXZ79_RS19465
uniprot id: A0A386HJT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

1604335:DXZ79 RS01630
gene id: 1604335:DXZ79_RS01630
uniprot id: A0A386HAD0
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS09180
gene id: 1604335:DXZ79_RS09180
uniprot id: A0A386HDF4
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS13020
gene id: 1604335:DXZ79_RS13020
uniprot id: A0A386HFT5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1604335:DXZ79 RS14520
gene id: 1604335:DXZ79_RS14520
uniprot id: A0A386HG17
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

1604335:DXZ79 RS10850
gene id: 1604335:DXZ79_RS10850
uniprot id: A0A386HEZ3
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1604335:DXZ79 RS12260
gene id: 1604335:DXZ79_RS12260
uniprot id: A0A386HG67
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1604335:DXZ79 RS12695
gene id: 1604335:DXZ79_RS12695
uniprot id: A0A386HGF8
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS18870
gene id: 1604335:DXZ79_RS18870
uniprot id: A0A386HI54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1604335:DXZ79 RS17700
gene id: 1604335:DXZ79_RS17700
uniprot id: A0A386HIK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1604335:DXZ79 RS20460
gene id: 1604335:DXZ79_RS20460
uniprot id: A0A386HIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

1604335:DXZ79 RS00380
gene id: 1604335:DXZ79_RS00380
uniprot id: A0A386H9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1604335:DXZ79 RS12205
gene id: 1604335:DXZ79_RS12205
uniprot id: A0A386HFF2
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1604335:DXZ79 RS05125
gene id: 1604335:DXZ79_RS05125
uniprot id: A0A386HC05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS13105
gene id: 1604335:DXZ79_RS13105
uniprot id: A0A386HFE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1604335:DXZ79 RS10670
gene id: 1604335:DXZ79_RS10670
uniprot id: A0A386HE51
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1604335:DXZ79 RS06120
gene id: 1604335:DXZ79_RS06120
uniprot id: A0A386HCU4
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS18460
gene id: 1604335:DXZ79_RS18460
uniprot id: A0A386HIZ0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1604335:DXZ79 RS02080
gene id: 1604335:DXZ79_RS02080
uniprot id: A0A8D4N1X9
names: Similarity
messages: Belongs to the transposase 8 family.

1604335:DXZ79 RS08695
gene id: 1604335:DXZ79_RS08695
uniprot id: A0A386HDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1604335:DXZ79 RS05910
gene id: 1604335:DXZ79_RS05910
uniprot id: A0A8D4N346
names: Similarity
messages: Belongs to the DapA family.

1604335:DXZ79 RS11555
gene id: 1604335:DXZ79_RS11555
uniprot id: A0A386HF86
names: Similarity
messages: Belongs to the peptidase S41A family.

1604335:DXZ79 RS15835
gene id: 1604335:DXZ79_RS15835
uniprot id: A0A386HH83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

1604335:DXZ79 RS06965
gene id: 1604335:DXZ79_RS06965
uniprot id: A0A386HCQ1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1604335:DXZ79 RS00140
gene id: 1604335:DXZ79_RS00140
uniprot id: A0A386H976
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1604335:DXZ79 RS03585
gene id: 1604335:DXZ79_RS03585
uniprot id: A0A386HB26
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1604335:DXZ79 RS17785
gene id: 1604335:DXZ79_RS17785
uniprot id: A0A386HI69
names: Similarity
messages: Belongs to the UPF0102 family.

1604335:DXZ79 RS03815
gene id: 1604335:DXZ79_RS03815
uniprot id: A0A386HAV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1604335:DXZ79 RS00370
gene id: 1604335:DXZ79_RS00370
uniprot id: A0A386H9P0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1604335:DXZ79 RS20545
gene id: 1604335:DXZ79_RS20545
uniprot id: A0A386HKD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1604335:DXZ79 RS07510
gene id: 1604335:DXZ79_RS07510
uniprot id: A0A386HD54
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS11255
gene id: 1604335:DXZ79_RS11255
uniprot id: A0A386HEK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

1604335:DXZ79 RS08630
gene id: 1604335:DXZ79_RS08630
uniprot id: A0A386HD72
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1604335:DXZ79 RS03845
gene id: 1604335:DXZ79_RS03845
uniprot id: A0A386HBD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1604335:DXZ79 RS02275
gene id: 1604335:DXZ79_RS02275
uniprot id: A0A386HAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1604335:DXZ79 RS12210
gene id: 1604335:DXZ79_RS12210
uniprot id: A0A8D4SNI0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1604335:DXZ79 RS02120
gene id: 1604335:DXZ79_RS02120
uniprot id: A0A8D4SP43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS09825
gene id: 1604335:DXZ79_RS09825
uniprot id: A0A386HED8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1604335:DXZ79 RS00580
gene id: 1604335:DXZ79_RS00580
uniprot id: A0A386HA41
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1604335:DXZ79 RS17875
gene id: 1604335:DXZ79_RS17875
uniprot id: A0A386HIN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1604335:DXZ79 RS02245
gene id: 1604335:DXZ79_RS02245
uniprot id: A0A386HAU5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1604335:DXZ79 RS20535
gene id: 1604335:DXZ79_RS20535
uniprot id: A0A386HJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1604335:DXZ79 RS07125
gene id: 1604335:DXZ79_RS07125
uniprot id: A0A386HD91
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

1604335:DXZ79 RS17260
gene id: 1604335:DXZ79_RS17260
uniprot id: A0A386HIC9
names: Subunit
messages: Monomer.

1604335:DXZ79 RS17915
gene id: 1604335:DXZ79_RS17915
uniprot id: A0A386HHP1
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

1604335:DXZ79 RS09370
gene id: 1604335:DXZ79_RS09370
uniprot id: A0A386HDV7
names: Similarity
messages: Belongs to the UPF0162 family.

1604335:DXZ79 RS06365
gene id: 1604335:DXZ79_RS06365
uniprot id: A0A386HCA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1604335:DXZ79 RS12065
gene id: 1604335:DXZ79_RS12065
uniprot id: A0A8D4N4M0
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS04190
gene id: 1604335:DXZ79_RS04190
uniprot id: A0A386HBS3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS05635
gene id: 1604335:DXZ79_RS05635
uniprot id: A0A386HCM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1604335:DXZ79 RS07665
gene id: 1604335:DXZ79_RS07665
uniprot id: A0A386HDD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1604335:DXZ79 RS11825
gene id: 1604335:DXZ79_RS11825
uniprot id: A0A386HF20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1604335:DXZ79 RS15100
gene id: 1604335:DXZ79_RS15100
uniprot id: A0A386HHA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

1604335:DXZ79 RS20350
gene id: 1604335:DXZ79_RS20350
uniprot id: A0A386HIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1604335:DXZ79 RS06590
gene id: 1604335:DXZ79_RS06590
uniprot id: A0A386HD26
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1604335:DXZ79 RS15275
gene id: 1604335:DXZ79_RS15275
uniprot id: A0A386HGY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1604335:DXZ79 RS17205
gene id: 1604335:DXZ79_RS17205
uniprot id: A0A386HI65
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS10805
gene id: 1604335:DXZ79_RS10805
uniprot id: A0A386HF16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

1604335:DXZ79 RS18200
gene id: 1604335:DXZ79_RS18200
uniprot id: A0A8D4SS29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1604335:DXZ79 RS15345
gene id: 1604335:DXZ79_RS15345
uniprot id: A0A386HH44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1604335:DXZ79 RS18995
gene id: 1604335:DXZ79_RS18995
uniprot id: A0A386HIT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1604335:DXZ79 RS13740
gene id: 1604335:DXZ79_RS13740
uniprot id: A0A386HG95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1604335:DXZ79 RS10280
gene id: 1604335:DXZ79_RS10280
uniprot id: A0A386HDZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1604335:DXZ79 RS11000
gene id: 1604335:DXZ79_RS11000
uniprot id: A0A386HF03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

1604335:DXZ79 RS06575
gene id: 1604335:DXZ79_RS06575
uniprot id: A0A386HC56
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1604335:DXZ79 RS08980
gene id: 1604335:DXZ79_RS08980
uniprot id: A0A8D4SQ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1604335:DXZ79 RS05320
gene id: 1604335:DXZ79_RS05320
uniprot id: A0A8D4N2X8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS06565
gene id: 1604335:DXZ79_RS06565
uniprot id: A0A386HCN2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS00585
gene id: 1604335:DXZ79_RS00585
uniprot id: A0A8D4SQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.

1604335:DXZ79 RS06580
gene id: 1604335:DXZ79_RS06580
uniprot id: A0A386HCW6
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1604335:DXZ79 RS05335
gene id: 1604335:DXZ79_RS05335
uniprot id: A0A8D4MY64
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS07390
gene id: 1604335:DXZ79_RS07390
uniprot id: A0A8D4N048
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1604335:DXZ79 RS05405
gene id: 1604335:DXZ79_RS05405
uniprot id: A0A386HCI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Probably plays an important role in intracellular peptide degradation.

1604335:DXZ79 RS16940
gene id: 1604335:DXZ79_RS16940
uniprot id: A0A386HHD2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1604335:DXZ79 RS18120
gene id: 1604335:DXZ79_RS18120
uniprot id: A0A386HIC7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1604335:DXZ79 RS01100
gene id: 1604335:DXZ79_RS01100
uniprot id: A0A386H9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1604335:DXZ79 RS14795
gene id: 1604335:DXZ79_RS14795
uniprot id: A0A386HG69
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1604335:DXZ79 RS18180
gene id: 1604335:DXZ79_RS18180
uniprot id: A0A386HHU3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1604335:DXZ79 RS08175
gene id: 1604335:DXZ79_RS08175
uniprot id: A0A8D4MZ04
names: Similarity
messages: Belongs to the thioesterase family.

1604335:DXZ79 RS02145
gene id: 1604335:DXZ79_RS02145
uniprot id: A0A386HAJ4
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS01415
gene id: 1604335:DXZ79_RS01415
uniprot id: A0A386HAH4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1604335:DXZ79 RS18355
gene id: 1604335:DXZ79_RS18355
uniprot id: A0A386HI95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(palmitoleoyl)-lipid IV(A).
messages: Cell inner membrane

1604335:DXZ79 RS09255
gene id: 1604335:DXZ79_RS09255
uniprot id: A0A386HDU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1604335:DXZ79 RS02430
gene id: 1604335:DXZ79_RS02430
uniprot id: A0A386HAU4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1604335:DXZ79 RS14900
gene id: 1604335:DXZ79_RS14900
uniprot id: A0A386HG90
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1604335:DXZ79 RS16330
gene id: 1604335:DXZ79_RS16330
uniprot id: A0A386HHG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1604335:DXZ79 RS08510
gene id: 1604335:DXZ79_RS08510
uniprot id: A0A386HDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1604335:DXZ79 RS10855
gene id: 1604335:DXZ79_RS10855
uniprot id: A0A386HF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS11680
gene id: 1604335:DXZ79_RS11680
uniprot id: A0A8D4N1F7
names: Function
names: Similarity
messages: Belongs to the class-C beta-lactamase family.
messages: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.

1604335:DXZ79 RS03880
gene id: 1604335:DXZ79_RS03880
uniprot id: A0A386HBD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1604335:DXZ79 RS04145
gene id: 1604335:DXZ79_RS04145
uniprot id: A0A386HB18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1604335:DXZ79 RS01220
gene id: 1604335:DXZ79_RS01220
uniprot id: A0A386HAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1604335:DXZ79 RS17975
gene id: 1604335:DXZ79_RS17975
uniprot id: A0A386HHQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1604335:DXZ79 RS01015
gene id: 1604335:DXZ79_RS01015
uniprot id: A0A386H9I4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1604335:DXZ79 RS14955
gene id: 1604335:DXZ79_RS14955
uniprot id: A0A386HGA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1604335:DXZ79 RS13840
gene id: 1604335:DXZ79_RS13840
uniprot id: A0A386HG86
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1604335:DXZ79 RS17245
gene id: 1604335:DXZ79_RS17245
uniprot id: A0A386HHE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS00640
gene id: 1604335:DXZ79_RS00640
uniprot id: A0A386H9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1604335:DXZ79 RS12030
gene id: 1604335:DXZ79_RS12030
uniprot id: A0A386HFK4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1604335:DXZ79 RS12420
gene id: 1604335:DXZ79_RS12420
uniprot id: A0A386HFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1604335:DXZ79 RS17670
gene id: 1604335:DXZ79_RS17670
uniprot id: A0A386HIC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS00915
gene id: 1604335:DXZ79_RS00915
uniprot id: A0A386HA98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1604335:DXZ79 RS19285
gene id: 1604335:DXZ79_RS19285
uniprot id: A0A386HIU6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1604335:DXZ79 RS13145
gene id: 1604335:DXZ79_RS13145
uniprot id: A0A386HFQ8
names: Similarity
messages: Belongs to the elongation factor P family.

1604335:DXZ79 RS19900
gene id: 1604335:DXZ79_RS19900
uniprot id: A0A386HIL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS11280
gene id: 1604335:DXZ79_RS11280
uniprot id: A0A386HF00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

1604335:DXZ79 RS04965
gene id: 1604335:DXZ79_RS04965
uniprot id: A0A386HBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS17380
gene id: 1604335:DXZ79_RS17380
uniprot id: A0A386HHT1
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS04330
gene id: 1604335:DXZ79_RS04330
uniprot id: A0A386HB43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

1604335:DXZ79 RS08325
gene id: 1604335:DXZ79_RS08325
uniprot id: A0A386HDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1604335:DXZ79 RS04445
gene id: 1604335:DXZ79_RS04445
uniprot id: A0A386HB78
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1604335:DXZ79 RS11195
gene id: 1604335:DXZ79_RS11195
uniprot id: A0A8D4N4A6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1604335:DXZ79 RS05885
gene id: 1604335:DXZ79_RS05885
uniprot id: A0A386HC83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1604335:DXZ79 RS02255
gene id: 1604335:DXZ79_RS02255
uniprot id: A0A386HAR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

1604335:DXZ79 RS18475
gene id: 1604335:DXZ79_RS18475
uniprot id: A0A386HJC7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1604335:DXZ79 RS07150
gene id: 1604335:DXZ79_RS07150
uniprot id: A0A386HD49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

1604335:DXZ79 RS10830
gene id: 1604335:DXZ79_RS10830
uniprot id: A0A386HEX6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1604335:DXZ79 RS06335
gene id: 1604335:DXZ79_RS06335
uniprot id: A0A386HC44
names: Function
names: Similarity
messages: Belongs to the GlgS family.
messages: Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.

1604335:DXZ79 RS01155
gene id: 1604335:DXZ79_RS01155
uniprot id: A0A8D4MZ35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

1604335:DXZ79 RS11330
gene id: 1604335:DXZ79_RS11330
uniprot id: A0A386HFD2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1604335:DXZ79 RS06405
gene id: 1604335:DXZ79_RS06405
uniprot id: A0A386HCM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1604335:DXZ79 RS19030
gene id: 1604335:DXZ79_RS19030
uniprot id: A0A386HIX6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1604335:DXZ79 RS20385
gene id: 1604335:DXZ79_RS20385
uniprot id: A0A386HJD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1604335:DXZ79 RS16280
gene id: 1604335:DXZ79_RS16280
uniprot id: A0A386HI94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1604335:DXZ79 RS13895
gene id: 1604335:DXZ79_RS13895
uniprot id: A0A8D4SRD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1604335:DXZ79 RS10155
gene id: 1604335:DXZ79_RS10155
uniprot id: A0A386HEX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1604335:DXZ79 RS20550
gene id: 1604335:DXZ79_RS20550
uniprot id: A0A386HJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1604335:DXZ79 RS01395
gene id: 1604335:DXZ79_RS01395
uniprot id: A0A386HA07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1604335:DXZ79 RS18340
gene id: 1604335:DXZ79_RS18340
uniprot id: A0A8D4SPK0
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS13100
gene id: 1604335:DXZ79_RS13100
uniprot id: A0A8D4N6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1604335:DXZ79 RS01705
gene id: 1604335:DXZ79_RS01705
uniprot id: A0A386H9R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1604335:DXZ79 RS11125
gene id: 1604335:DXZ79_RS11125
uniprot id: A0A386HEP1
names: Similarity
messages: Belongs to the pyruvate kinase family.

1604335:DXZ79 RS05870
gene id: 1604335:DXZ79_RS05870
uniprot id: A0A386HC34
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1604335:DXZ79 RS17645
gene id: 1604335:DXZ79_RS17645
uniprot id: A0A386HHX6
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

1604335:DXZ79 RS06990
gene id: 1604335:DXZ79_RS06990
uniprot id: A0A386HCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

1604335:DXZ79 RS06280
gene id: 1604335:DXZ79_RS06280
uniprot id: A0A386HC08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

1604335:DXZ79 RS03250
gene id: 1604335:DXZ79_RS03250
uniprot id: A0A386HBA1
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS09205
gene id: 1604335:DXZ79_RS09205
uniprot id: A0A386HDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1604335:DXZ79 RS20290
gene id: 1604335:DXZ79_RS20290
uniprot id: A0A386HJB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
messages: Cell membrane

1604335:DXZ79 RS02885
gene id: 1604335:DXZ79_RS02885
uniprot id: A0A386HAK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1604335:DXZ79 RS17310
gene id: 1604335:DXZ79_RS17310
uniprot id: A0A386HID6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

1604335:DXZ79 RS12615
gene id: 1604335:DXZ79_RS12615
uniprot id: A0A386HF30
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1604335:DXZ79 RS09380
gene id: 1604335:DXZ79_RS09380
uniprot id: A0A8D4N501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1604335:DXZ79 RS12775
gene id: 1604335:DXZ79_RS12775
uniprot id: A0A386HFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1604335:DXZ79 RS18955
gene id: 1604335:DXZ79_RS18955
uniprot id: A0A386HJK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1604335:DXZ79 RS03620
gene id: 1604335:DXZ79_RS03620
uniprot id: A0A386HAW7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1604335:DXZ79 RS04600
gene id: 1604335:DXZ79_RS04600
uniprot id: A0A386HBR0
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS14800
gene id: 1604335:DXZ79_RS14800
uniprot id: A0A386HGU5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1604335:DXZ79 RS16845
gene id: 1604335:DXZ79_RS16845
uniprot id: A0A386HHP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1604335:DXZ79 RS00535
gene id: 1604335:DXZ79_RS00535
uniprot id: A0A386H9S1
names: Similarity
messages: Belongs to the FBPase class 2 family.

1604335:DXZ79 RS02515
gene id: 1604335:DXZ79_RS02515
uniprot id: A0A386HAN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1604335:DXZ79 RS13240
gene id: 1604335:DXZ79_RS13240
uniprot id: A0A386HGC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1604335:DXZ79 RS14675
gene id: 1604335:DXZ79_RS14675
uniprot id: A0A386HG53
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1604335:DXZ79 RS00355
gene id: 1604335:DXZ79_RS00355
uniprot id: A0A386H9R4
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

1604335:DXZ79 RS09415
gene id: 1604335:DXZ79_RS09415
uniprot id: A0A386HEA8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

1604335:DXZ79 RS04610
gene id: 1604335:DXZ79_RS04610
uniprot id: A0A386HB87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1604335:DXZ79 RS06415
gene id: 1604335:DXZ79_RS06415
uniprot id: A0A386HCB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1604335:DXZ79 RS03850
gene id: 1604335:DXZ79_RS03850
uniprot id: A0A386HBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1604335:DXZ79 RS09960
gene id: 1604335:DXZ79_RS09960
uniprot id: A0A386HEG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1604335:DXZ79 RS02625
gene id: 1604335:DXZ79_RS02625
uniprot id: A0A386HAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1604335:DXZ79 RS11540
gene id: 1604335:DXZ79_RS11540
uniprot id: A0A386HFT7
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS03380
gene id: 1604335:DXZ79_RS03380
uniprot id: A0A8D4MZH3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1604335:DXZ79 RS02525
gene id: 1604335:DXZ79_RS02525
uniprot id: A0A386HA68
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1604335:DXZ79 RS09030
gene id: 1604335:DXZ79_RS09030
uniprot id: A0A8D4SRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1604335:DXZ79 RS09575
gene id: 1604335:DXZ79_RS09575
uniprot id: A0A386HE65
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

1604335:DXZ79 RS05455
gene id: 1604335:DXZ79_RS05455
uniprot id: A0A386HCC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1604335:DXZ79 RS09440
gene id: 1604335:DXZ79_RS09440
uniprot id: A0A386HE71
names: Similarity
messages: Belongs to the UPF0502 family.

1604335:DXZ79 RS05945
gene id: 1604335:DXZ79_RS05945
uniprot id: A0A386HCD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1604335:DXZ79 RS05155
gene id: 1604335:DXZ79_RS05155
uniprot id: A0A386HBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

1604335:DXZ79 RS16795
gene id: 1604335:DXZ79_RS16795
uniprot id: A0A386HIH5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1604335:DXZ79 RS08555
gene id: 1604335:DXZ79_RS08555
uniprot id: A0A386HDI3
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1604335:DXZ79 RS03570
gene id: 1604335:DXZ79_RS03570
uniprot id: A0A386HAV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

1604335:DXZ79 RS09785
gene id: 1604335:DXZ79_RS09785
uniprot id: A0A386HEH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1604335:DXZ79 RS11285
gene id: 1604335:DXZ79_RS11285
uniprot id: A0A386HFI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1604335:DXZ79 RS19105
gene id: 1604335:DXZ79_RS19105
uniprot id: A0A386HIS5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1604335:DXZ79 RS09505
gene id: 1604335:DXZ79_RS09505
uniprot id: A0A386HE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1604335:DXZ79 RS00830
gene id: 1604335:DXZ79_RS00830
uniprot id: A0A386H9Y7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS11270
gene id: 1604335:DXZ79_RS11270
uniprot id: A0A386HFB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS13550
gene id: 1604335:DXZ79_RS13550
uniprot id: A0A386HGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1604335:DXZ79 RS08845
gene id: 1604335:DXZ79_RS08845
uniprot id: A0A386HDW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

1604335:DXZ79 RS19005
gene id: 1604335:DXZ79_RS19005
uniprot id: A0A386HJK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1604335:DXZ79 RS14150
gene id: 1604335:DXZ79_RS14150
uniprot id: A0A386HGN0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1604335:DXZ79 RS03415
gene id: 1604335:DXZ79_RS03415
uniprot id: A0A386HAZ6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1604335:DXZ79 RS02370
gene id: 1604335:DXZ79_RS02370
uniprot id: A0A386HAN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1604335:DXZ79 RS10275
gene id: 1604335:DXZ79_RS10275
uniprot id: A0A8D4N244
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

1604335:DXZ79 RS15690
gene id: 1604335:DXZ79_RS15690
uniprot id: A0A386HHB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1604335:DXZ79 RS00390
gene id: 1604335:DXZ79_RS00390
uniprot id: A0A8D4SNU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1604335:DXZ79 RS08835
gene id: 1604335:DXZ79_RS08835
uniprot id: A0A386HE81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1604335:DXZ79 RS05210
gene id: 1604335:DXZ79_RS05210
uniprot id: A0A386HBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS04135
gene id: 1604335:DXZ79_RS04135
uniprot id: A0A386HBC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1604335:DXZ79 RS02785
gene id: 1604335:DXZ79_RS02785
uniprot id: A0A386HAV7
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

1604335:DXZ79 RS06425
gene id: 1604335:DXZ79_RS06425
uniprot id: A0A386HCX0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1604335:DXZ79 RS20500
gene id: 1604335:DXZ79_RS20500
uniprot id: A0A386HJF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1604335:DXZ79 RS11420
gene id: 1604335:DXZ79_RS11420
uniprot id: A0A386HF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS07640
gene id: 1604335:DXZ79_RS07640
uniprot id: A0A386HDJ6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1604335:DXZ79 RS00615
gene id: 1604335:DXZ79_RS00615
uniprot id: A0A386H9V9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1604335:DXZ79 RS02555
gene id: 1604335:DXZ79_RS02555
uniprot id: A0A386HB29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS02400
gene id: 1604335:DXZ79_RS02400
uniprot id: A0A386HAH9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1604335:DXZ79 RS13180
gene id: 1604335:DXZ79_RS13180
uniprot id: A0A386HG61
names: Similarity
messages: Belongs to the peptidase C40 family.

1604335:DXZ79 RS18195
gene id: 1604335:DXZ79_RS18195
uniprot id: A0A8D4SRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1604335:DXZ79 RS06750
gene id: 1604335:DXZ79_RS06750
uniprot id: A0A386HD55
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1604335:DXZ79 RS05030
gene id: 1604335:DXZ79_RS05030
uniprot id: A0A386HBY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HdeB family.
messages: Periplasm
messages: Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.

1604335:DXZ79 RS11755
gene id: 1604335:DXZ79_RS11755
uniprot id: A0A8D4N3Q2
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

1604335:DXZ79 RS14670
gene id: 1604335:DXZ79_RS14670
uniprot id: A0A386HGQ8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1604335:DXZ79 RS00340
gene id: 1604335:DXZ79_RS00340
uniprot id: A0A386H9T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1604335:DXZ79 RS01270
gene id: 1604335:DXZ79_RS01270
uniprot id: A0A386H9K0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1604335:DXZ79 RS11050
gene id: 1604335:DXZ79_RS11050
uniprot id: A0A8E4BMU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1604335:DXZ79 RS06600
gene id: 1604335:DXZ79_RS06600
uniprot id: A0A386HCL5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1604335:DXZ79 RS17090
gene id: 1604335:DXZ79_RS17090
uniprot id: A0A386HI02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1604335:DXZ79 RS07020
gene id: 1604335:DXZ79_RS07020
uniprot id: A0A386HCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS00020
gene id: 1604335:DXZ79_RS00020
uniprot id: A0A386H9K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1604335:DXZ79 RS12715
gene id: 1604335:DXZ79_RS12715
uniprot id: A0A386HF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1604335:DXZ79 RS05980
gene id: 1604335:DXZ79_RS05980
uniprot id: A0A386HCS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1604335:DXZ79 RS16365
gene id: 1604335:DXZ79_RS16365
uniprot id: A0A8D4N2W8
names: Similarity
messages: Belongs to the UPF0235 family.

1604335:DXZ79 RS09670
gene id: 1604335:DXZ79_RS09670
uniprot id: A0A386HEB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1604335:DXZ79 RS13065
gene id: 1604335:DXZ79_RS13065
uniprot id: A0A386HG99
names: Similarity
messages: Belongs to the GST superfamily.

1604335:DXZ79 RS13780
gene id: 1604335:DXZ79_RS13780
uniprot id: A0A386HH03
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1604335:DXZ79 RS05735
gene id: 1604335:DXZ79_RS05735
uniprot id: A0A386HBW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1604335:DXZ79 RS11935
gene id: 1604335:DXZ79_RS11935
uniprot id: A0A386HF39
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS20450
gene id: 1604335:DXZ79_RS20450
uniprot id: A0A386HJE6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1604335:DXZ79 RS10080
gene id: 1604335:DXZ79_RS10080
uniprot id: A0A8D4SQE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1604335:DXZ79 RS00250
gene id: 1604335:DXZ79_RS00250
uniprot id: A0A386H955
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1604335:DXZ79 RS05435
gene id: 1604335:DXZ79_RS05435
uniprot id: A0A386HBZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1604335:DXZ79 RS02330
gene id: 1604335:DXZ79_RS02330
uniprot id: A0A386HA94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1604335:DXZ79 RS02340
gene id: 1604335:DXZ79_RS02340
uniprot id: A0A386HAZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1604335:DXZ79 RS11770
gene id: 1604335:DXZ79_RS11770
uniprot id: A0A8D4N4Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1604335:DXZ79 RS03645
gene id: 1604335:DXZ79_RS03645
uniprot id: A0A8D4MZY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1604335:DXZ79 RS17330
gene id: 1604335:DXZ79_RS17330
uniprot id: A0A8E4BMJ1
names: Similarity
messages: Belongs to the UPF0441 family.

1604335:DXZ79 RS15010
gene id: 1604335:DXZ79_RS15010
uniprot id: A0A386HGT9
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS09360
gene id: 1604335:DXZ79_RS09360
uniprot id: A0A386HE25
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1604335:DXZ79 RS11490
gene id: 1604335:DXZ79_RS11490
uniprot id: A0A386HEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS01515
gene id: 1604335:DXZ79_RS01515
uniprot id: A0A386HAB4
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS06735
gene id: 1604335:DXZ79_RS06735
uniprot id: A0A386HC87
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

1604335:DXZ79 RS10475
gene id: 1604335:DXZ79_RS10475
uniprot id: A0A386HF33
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS03835
gene id: 1604335:DXZ79_RS03835
uniprot id: A0A8D4N2N9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1604335:DXZ79 RS12780
gene id: 1604335:DXZ79_RS12780
uniprot id: A0A386HG48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1604335:DXZ79 RS00970
gene id: 1604335:DXZ79_RS00970
uniprot id: A0A386HA29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

1604335:DXZ79 RS19275
gene id: 1604335:DXZ79_RS19275
uniprot id: A0A386HJC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1604335:DXZ79 RS19655
gene id: 1604335:DXZ79_RS19655
uniprot id: A0A386HII1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1604335:DXZ79 RS09285
gene id: 1604335:DXZ79_RS09285
uniprot id: A0A386HE36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS03920
gene id: 1604335:DXZ79_RS03920
uniprot id: A0A386HBC8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1604335:DXZ79 RS02125
gene id: 1604335:DXZ79_RS02125
uniprot id: A0A386HAH8
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
messages: Catalyzes the reduction of tatronate semialdehyde to D-glycerate.

1604335:DXZ79 RS12650
gene id: 1604335:DXZ79_RS12650
uniprot id: A0A386HFH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

1604335:DXZ79 RS19070
gene id: 1604335:DXZ79_RS19070
uniprot id: A0A386HJ03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1604335:DXZ79 RS18350
gene id: 1604335:DXZ79_RS18350
uniprot id: A0A386HIX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1604335:DXZ79 RS03605
gene id: 1604335:DXZ79_RS03605
uniprot id: A0A386HBF9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1604335:DXZ79 RS03670
gene id: 1604335:DXZ79_RS03670
uniprot id: A0A386HBG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS04045
gene id: 1604335:DXZ79_RS04045
uniprot id: A0A386HAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS00255
gene id: 1604335:DXZ79_RS00255
uniprot id: A0A8D4N2W9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS18800
gene id: 1604335:DXZ79_RS18800
uniprot id: A0A386HIZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1604335:DXZ79 RS10135
gene id: 1604335:DXZ79_RS10135
uniprot id: A0A386HEK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS05730
gene id: 1604335:DXZ79_RS05730
uniprot id: A0A8E4DFG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1604335:DXZ79 RS19205
gene id: 1604335:DXZ79_RS19205
uniprot id: A0A386HIA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS09515
gene id: 1604335:DXZ79_RS09515
uniprot id: A0A386HEC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1604335:DXZ79 RS04620
gene id: 1604335:DXZ79_RS04620
uniprot id: A0A386HBR9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

1604335:DXZ79 RS11095
gene id: 1604335:DXZ79_RS11095
uniprot id: A0A386HEW8
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

1604335:DXZ79 RS00935
gene id: 1604335:DXZ79_RS00935
uniprot id: A0A386H9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS18860
gene id: 1604335:DXZ79_RS18860
uniprot id: A0A386HIW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1604335:DXZ79 RS11315
gene id: 1604335:DXZ79_RS11315
uniprot id: A0A386HF52
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1604335:DXZ79 RS10395
gene id: 1604335:DXZ79_RS10395
uniprot id: A0A386HEN2
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS03385
gene id: 1604335:DXZ79_RS03385
uniprot id: A0A386HBB9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1604335:DXZ79 RS01655
gene id: 1604335:DXZ79_RS01655
uniprot id: A0A386H9R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS05835
gene id: 1604335:DXZ79_RS05835
uniprot id: A0A386HCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1604335:DXZ79 RS07305
gene id: 1604335:DXZ79_RS07305
uniprot id: A0A386HCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS08530
gene id: 1604335:DXZ79_RS08530
uniprot id: A0A386HD57
names: Similarity
messages: Belongs to the MotB family.

1604335:DXZ79 RS06970
gene id: 1604335:DXZ79_RS06970
uniprot id: A0A386HCU2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1604335:DXZ79 RS18630
gene id: 1604335:DXZ79_RS18630
uniprot id: A0A386HIJ4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1604335:DXZ79 RS04910
gene id: 1604335:DXZ79_RS04910
uniprot id: A0A386HC40
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asr family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Proteolytic processing gives rise to the active protein.
messages: Required for growth and/or survival at acidic conditions.

1604335:DXZ79 RS12925
gene id: 1604335:DXZ79_RS12925
uniprot id: A0A386HFB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1604335:DXZ79 RS04870
gene id: 1604335:DXZ79_RS04870
uniprot id: A0A386HBV0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1604335:DXZ79 RS08610
gene id: 1604335:DXZ79_RS08610
uniprot id: A0A386HE35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1604335:DXZ79 RS01030
gene id: 1604335:DXZ79_RS01030
uniprot id: A0A386HA47
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1604335:DXZ79 RS04760
gene id: 1604335:DXZ79_RS04760
uniprot id: A0A386HBJ2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1604335:DXZ79 RS20345
gene id: 1604335:DXZ79_RS20345
uniprot id: A0A386HJK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1604335:DXZ79 RS04730
gene id: 1604335:DXZ79_RS04730
uniprot id: A0A8D4N298
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS18480
gene id: 1604335:DXZ79_RS18480
uniprot id: A0A386HKA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1604335:DXZ79 RS18850
gene id: 1604335:DXZ79_RS18850
uniprot id: A0A386HJH7
names: Similarity
messages: Belongs to the Smg family.

1604335:DXZ79 RS10125
gene id: 1604335:DXZ79_RS10125
uniprot id: A0A8E4BMC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

1604335:DXZ79 RS10455
gene id: 1604335:DXZ79_RS10455
uniprot id: A0A386HER4
names: Similarity
messages: Belongs to the ArsC family.

1604335:DXZ79 RS05575
gene id: 1604335:DXZ79_RS05575
uniprot id: A0A8E4BJN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

1604335:DXZ79 RS03780
gene id: 1604335:DXZ79_RS03780
uniprot id: A0A386HB05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

1604335:DXZ79 RS05005
gene id: 1604335:DXZ79_RS05005
uniprot id: A0A386HCA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1604335:DXZ79 RS20280
gene id: 1604335:DXZ79_RS20280
uniprot id: A0A386HJB5
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

1604335:DXZ79 RS18110
gene id: 1604335:DXZ79_RS18110
uniprot id: A0A386HIB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS18750
gene id: 1604335:DXZ79_RS18750
uniprot id: A0A386HIL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1604335:DXZ79 RS09320
gene id: 1604335:DXZ79_RS09320
uniprot id: A0A386HE48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1604335:DXZ79 RS00485
gene id: 1604335:DXZ79_RS00485
uniprot id: A0A386H992
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1604335:DXZ79 RS05990
gene id: 1604335:DXZ79_RS05990
uniprot id: A0A386HCC4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1604335:DXZ79 RS02730
gene id: 1604335:DXZ79_RS02730
uniprot id: A0A386HB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS15485
gene id: 1604335:DXZ79_RS15485
uniprot id: A0A386HH73
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1604335:DXZ79 RS17000
gene id: 1604335:DXZ79_RS17000
uniprot id: A0A8D4N333
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1604335:DXZ79 RS15270
gene id: 1604335:DXZ79_RS15270
uniprot id: A0A386HHQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1604335:DXZ79 RS08685
gene id: 1604335:DXZ79_RS08685
uniprot id: A0A386HD86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1604335:DXZ79 RS11445
gene id: 1604335:DXZ79_RS11445
uniprot id: A0A386HEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS08690
gene id: 1604335:DXZ79_RS08690
uniprot id: A0A386HD81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1604335:DXZ79 RS09065
gene id: 1604335:DXZ79_RS09065
uniprot id: A0A386HDY9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS02470
gene id: 1604335:DXZ79_RS02470
uniprot id: A0A386HA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1604335:DXZ79 RS04690
gene id: 1604335:DXZ79_RS04690
uniprot id: A0A386HC00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1604335:DXZ79 RS18740
gene id: 1604335:DXZ79_RS18740
uniprot id: A0A386HJH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS12810
gene id: 1604335:DXZ79_RS12810
uniprot id: A0A386HF70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1604335:DXZ79 RS05195
gene id: 1604335:DXZ79_RS05195
uniprot id: A0A386HBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1604335:DXZ79 RS03530
gene id: 1604335:DXZ79_RS03530
uniprot id: A0A386HB17
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS18150
gene id: 1604335:DXZ79_RS18150
uniprot id: A0A386HIS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1604335:DXZ79 RS16210
gene id: 1604335:DXZ79_RS16210
uniprot id: A0A386HHN0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1604335:DXZ79 RS11850
gene id: 1604335:DXZ79_RS11850
uniprot id: A0A386HFH6
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1604335:DXZ79 RS06390
gene id: 1604335:DXZ79_RS06390
uniprot id: A0A386HC53
names: Similarity
messages: Belongs to the UPF0250 family.

1604335:DXZ79 RS18535
gene id: 1604335:DXZ79_RS18535
uniprot id: A0A386HII5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1604335:DXZ79 RS10335
gene id: 1604335:DXZ79_RS10335
uniprot id: A0A386HDZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

1604335:DXZ79 RS08660
gene id: 1604335:DXZ79_RS08660
uniprot id: A0A8E4BMB4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1604335:DXZ79 RS19180
gene id: 1604335:DXZ79_RS19180
uniprot id: A0A386HIT0
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1604335:DXZ79 RS15145
gene id: 1604335:DXZ79_RS15145
uniprot id: A0A386HH53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

1604335:DXZ79 RS01105
gene id: 1604335:DXZ79_RS01105
uniprot id: A0A386HA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1604335:DXZ79 RS14510
gene id: 1604335:DXZ79_RS14510
uniprot id: A0A386HGM8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1604335:DXZ79 RS13495
gene id: 1604335:DXZ79_RS13495
uniprot id: A0A386HG06
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1604335:DXZ79 RS10460
gene id: 1604335:DXZ79_RS10460
uniprot id: A0A386HEV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1604335:DXZ79 RS14055
gene id: 1604335:DXZ79_RS14055
uniprot id: A0A386HGF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1604335:DXZ79 RS20090
gene id: 1604335:DXZ79_RS20090
uniprot id: A0A386HJF7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1604335:DXZ79 RS10880
gene id: 1604335:DXZ79_RS10880
uniprot id: A0A386HEJ9
names: Similarity
messages: Belongs to the PspA/IM30 family.

1604335:DXZ79 RS18450
gene id: 1604335:DXZ79_RS18450
uniprot id: A0A386HIT7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1604335:DXZ79 RS15035
gene id: 1604335:DXZ79_RS15035
uniprot id: A0A8D4N2H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1604335:DXZ79 RS06720
gene id: 1604335:DXZ79_RS06720
uniprot id: A0A386HCM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1604335:DXZ79 RS13190
gene id: 1604335:DXZ79_RS13190
uniprot id: A0A8D4N5J8
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS02265
gene id: 1604335:DXZ79_RS02265
uniprot id: A0A386HAM1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1604335:DXZ79 RS13085
gene id: 1604335:DXZ79_RS13085
uniprot id: A0A8D4N1V9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS05010
gene id: 1604335:DXZ79_RS05010
uniprot id: A0A386HBN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1604335:DXZ79 RS06500
gene id: 1604335:DXZ79_RS06500
uniprot id: A0A386HCV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS05170
gene id: 1604335:DXZ79_RS05170
uniprot id: A0A386HBL1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1604335:DXZ79 RS15280
gene id: 1604335:DXZ79_RS15280
uniprot id: A0A386HH33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1604335:DXZ79 RS05250
gene id: 1604335:DXZ79_RS05250
uniprot id: A0A8D4MY54
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1604335:DXZ79 RS17265
gene id: 1604335:DXZ79_RS17265
uniprot id: A0A386HHR6
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1604335:DXZ79 RS03900
gene id: 1604335:DXZ79_RS03900
uniprot id: A0A386HBE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1604335:DXZ79 RS04170
gene id: 1604335:DXZ79_RS04170
uniprot id: A0A386HBQ0
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS08080
gene id: 1604335:DXZ79_RS08080
uniprot id: A0A8D4N4K7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS09590
gene id: 1604335:DXZ79_RS09590
uniprot id: A0A386HE97
names: Similarity
messages: Belongs to the RutC family.

1604335:DXZ79 RS15290
gene id: 1604335:DXZ79_RS15290
uniprot id: A0A386HGG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1604335:DXZ79 RS11245
gene id: 1604335:DXZ79_RS11245
uniprot id: A0A386HF46
names: Similarity
messages: Belongs to the peptidase C40 family.

1604335:DXZ79 RS13040
gene id: 1604335:DXZ79_RS13040
uniprot id: A0A386HFA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS16830
gene id: 1604335:DXZ79_RS16830
uniprot id: A0A8D4ST93
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1604335:DXZ79 RS20470
gene id: 1604335:DXZ79_RS20470
uniprot id: A0A386HJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS04695
gene id: 1604335:DXZ79_RS04695
uniprot id: A0A386HBS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1604335:DXZ79 RS12225
gene id: 1604335:DXZ79_RS12225
uniprot id: A0A386HEW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1604335:DXZ79 RS13505
gene id: 1604335:DXZ79_RS13505
uniprot id: A0A8D4SSS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1604335:DXZ79 RS00405
gene id: 1604335:DXZ79_RS00405
uniprot id: A0A386H9V7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1604335:DXZ79 RS13140
gene id: 1604335:DXZ79_RS13140
uniprot id: A0A386HGP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

1604335:DXZ79 RS05470
gene id: 1604335:DXZ79_RS05470
uniprot id: A0A386HBX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1604335:DXZ79 RS02650
gene id: 1604335:DXZ79_RS02650
uniprot id: A0A386HAS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1604335:DXZ79 RS05460
gene id: 1604335:DXZ79_RS05460
uniprot id: A0A386HC58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS03080
gene id: 1604335:DXZ79_RS03080
uniprot id: A0A386HB68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

1604335:DXZ79 RS10665
gene id: 1604335:DXZ79_RS10665
uniprot id: A0A386HEG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1604335:DXZ79 RS12725
gene id: 1604335:DXZ79_RS12725
uniprot id: A0A386HFY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS03165
gene id: 1604335:DXZ79_RS03165
uniprot id: A0A8D4SM00
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1604335:DXZ79 RS00530
gene id: 1604335:DXZ79_RS00530
uniprot id: A0A8E4DFF2
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS15855
gene id: 1604335:DXZ79_RS15855
uniprot id: A0A8D4N2R0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS07070
gene id: 1604335:DXZ79_RS07070
uniprot id: A0A386HD74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1604335:DXZ79 RS04770
gene id: 1604335:DXZ79_RS04770
uniprot id: A0A386HC21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1604335:DXZ79 RS13585
gene id: 1604335:DXZ79_RS13585
uniprot id: A0A386HG82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1604335:DXZ79 RS05740
gene id: 1604335:DXZ79_RS05740
uniprot id: A0A386HBS7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1604335:DXZ79 RS17840
gene id: 1604335:DXZ79_RS17840
uniprot id: A0A386HI79
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1604335:DXZ79 RS20155
gene id: 1604335:DXZ79_RS20155
uniprot id: A0A386HJS8
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1604335:DXZ79 RS02235
gene id: 1604335:DXZ79_RS02235
uniprot id: A0A386HA02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

1604335:DXZ79 RS13370
gene id: 1604335:DXZ79_RS13370
uniprot id: A0A386HGF2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

1604335:DXZ79 RS03465
gene id: 1604335:DXZ79_RS03465
uniprot id: A0A386HBF7
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1604335:DXZ79 RS12100
gene id: 1604335:DXZ79_RS12100
uniprot id: A0A8D4N6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1604335:DXZ79 RS09225
gene id: 1604335:DXZ79_RS09225
uniprot id: A0A386HDG5
names: Function
names: Similarity
messages: Belongs to the arginine N-succinyltransferase family.
messages: Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.

1604335:DXZ79 RS05920
gene id: 1604335:DXZ79_RS05920
uniprot id: A0A386HCR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ROK (NagC/XylR) family. NanK subfamily.
messages: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
messages: Homodimer.

1604335:DXZ79 RS04815
gene id: 1604335:DXZ79_RS04815
uniprot id: A0A8D4N3P5
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS09885
gene id: 1604335:DXZ79_RS09885
uniprot id: A0A386HEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1604335:DXZ79 RS15390
gene id: 1604335:DXZ79_RS15390
uniprot id: A0A386HH61
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1604335:DXZ79 RS12745
gene id: 1604335:DXZ79_RS12745
uniprot id: A0A386HGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1604335:DXZ79 RS05050
gene id: 1604335:DXZ79_RS05050
uniprot id: A0A8D4MZI4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1604335:DXZ79 RS18405
gene id: 1604335:DXZ79_RS18405
uniprot id: A0A386HIX8
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1604335:DXZ79 RS12250
gene id: 1604335:DXZ79_RS12250
uniprot id: A0A386HF15
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1604335:DXZ79 RS05775
gene id: 1604335:DXZ79_RS05775
uniprot id: A0A8D4SME0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1604335:DXZ79 RS14910
gene id: 1604335:DXZ79_RS14910
uniprot id: A0A8E4GYB2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1604335:DXZ79 RS09620
gene id: 1604335:DXZ79_RS09620
uniprot id: A0A386HE93
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1604335:DXZ79 RS04240
gene id: 1604335:DXZ79_RS04240
uniprot id: A0A8D4N052
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1604335:DXZ79 RS00925
gene id: 1604335:DXZ79_RS00925
uniprot id: A0A386H9Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS02365
gene id: 1604335:DXZ79_RS02365
uniprot id: A0A386HAW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

1604335:DXZ79 RS02135
gene id: 1604335:DXZ79_RS02135
uniprot id: A0A386HA04
names: Similarity
messages: Belongs to the CdaR family.

1604335:DXZ79 RS12570
gene id: 1604335:DXZ79_RS12570
uniprot id: A0A386HF56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1604335:DXZ79 RS08790
gene id: 1604335:DXZ79_RS08790
uniprot id: A0A386HDK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
messages: Homodimer.

1604335:DXZ79 RS16180
gene id: 1604335:DXZ79_RS16180
uniprot id: A0A8D4ST59
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1604335:DXZ79 RS07435
gene id: 1604335:DXZ79_RS07435
uniprot id: A0A386HCK7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1604335:DXZ79 RS17055
gene id: 1604335:DXZ79_RS17055
uniprot id: A0A386HIM3
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS12035
gene id: 1604335:DXZ79_RS12035
uniprot id: A0A386HFP4
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1604335:DXZ79 RS04585
gene id: 1604335:DXZ79_RS04585
uniprot id: A0A386HBQ6
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

1604335:DXZ79 RS09955
gene id: 1604335:DXZ79_RS09955
uniprot id: A0A386HEG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1604335:DXZ79 RS08795
gene id: 1604335:DXZ79_RS08795
uniprot id: A0A386HDV2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1604335:DXZ79 RS10105
gene id: 1604335:DXZ79_RS10105
uniprot id: A0A386HE63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1604335:DXZ79 RS07730
gene id: 1604335:DXZ79_RS07730
uniprot id: A0A386HDK9
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1604335:DXZ79 RS03560
gene id: 1604335:DXZ79_RS03560
uniprot id: A0A386HB72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1604335:DXZ79 RS06815
gene id: 1604335:DXZ79_RS06815
uniprot id: A0A386HD38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1604335:DXZ79 RS05360
gene id: 1604335:DXZ79_RS05360
uniprot id: A0A386HC22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS18115
gene id: 1604335:DXZ79_RS18115
uniprot id: A0A386HJ58
names: Similarity
messages: Belongs to the peptidase U62 family.

1604335:DXZ79 RS16140
gene id: 1604335:DXZ79_RS16140
uniprot id: A0A386HGW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1604335:DXZ79 RS00625
gene id: 1604335:DXZ79_RS00625
uniprot id: A0A386H9H7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1604335:DXZ79 RS05745
gene id: 1604335:DXZ79_RS05745
uniprot id: A0A386HCH7
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS08110
gene id: 1604335:DXZ79_RS08110
uniprot id: A0A386HDH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1604335:DXZ79 RS03665
gene id: 1604335:DXZ79_RS03665
uniprot id: A0A386HB94
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1604335:DXZ79 RS15665
gene id: 1604335:DXZ79_RS15665
uniprot id: A0A8D4SST8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

1604335:DXZ79 RS00265
gene id: 1604335:DXZ79_RS00265
uniprot id: A0A386H9P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1604335:DXZ79 RS11250
gene id: 1604335:DXZ79_RS11250
uniprot id: A0A386HEF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

1604335:DXZ79 RS00825
gene id: 1604335:DXZ79_RS00825
uniprot id: A0A386HA73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1604335:DXZ79 RS11075
gene id: 1604335:DXZ79_RS11075
uniprot id: A0A386HF10
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

1604335:DXZ79 RS05950
gene id: 1604335:DXZ79_RS05950
uniprot id: A0A386HC03
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1604335:DXZ79 RS08490
gene id: 1604335:DXZ79_RS08490
uniprot id: A0A386HDN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS02345
gene id: 1604335:DXZ79_RS02345
uniprot id: A0A386HAG7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1604335:DXZ79 RS14605
gene id: 1604335:DXZ79_RS14605
uniprot id: A0A8D4N2C2
names: Subcellular Location Annotation
messages: Cell inner membrane

1604335:DXZ79 RS01050
gene id: 1604335:DXZ79_RS01050
uniprot id: A0A386H9V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS20480
gene id: 1604335:DXZ79_RS20480
uniprot id: A0A386HJY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1604335:DXZ79 RS12465
gene id: 1604335:DXZ79_RS12465
uniprot id: A0A386HFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

1604335:DXZ79 RS06480
gene id: 1604335:DXZ79_RS06480
uniprot id: A0A386HCH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS19420
gene id: 1604335:DXZ79_RS19420
uniprot id: A0A386HIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1604335:DXZ79 RS01420
gene id: 1604335:DXZ79_RS01420
uniprot id: A0A386HA83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

1604335:DXZ79 RS02440
gene id: 1604335:DXZ79_RS02440
uniprot id: A0A8D4MXC3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1604335:DXZ79 RS11470
gene id: 1604335:DXZ79_RS11470
uniprot id: A0A386HEP2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1604335:DXZ79 RS14925
gene id: 1604335:DXZ79_RS14925
uniprot id: A0A386HH69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1604335:DXZ79 RS05115
gene id: 1604335:DXZ79_RS05115
uniprot id: A0A386HC64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1604335:DXZ79 RS06680
gene id: 1604335:DXZ79_RS06680
uniprot id: A0A386HC76
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1604335:DXZ79 RS12445
gene id: 1604335:DXZ79_RS12445
uniprot id: A0A386HEZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

1604335:DXZ79 RS18540
gene id: 1604335:DXZ79_RS18540
uniprot id: A0A386HJD8
names: Similarity
messages: Belongs to the aspartokinase family.

1604335:DXZ79 RS04155
gene id: 1604335:DXZ79_RS04155
uniprot id: A0A386HB09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

1604335:DXZ79 RS18550
gene id: 1604335:DXZ79_RS18550
uniprot id: A0A8D4N4Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

1604335:DXZ79 RS07915
gene id: 1604335:DXZ79_RS07915
uniprot id: A0A386HD84
names: Similarity
messages: Belongs to the CobH/CbiC family.

1604335:DXZ79 RS01340
gene id: 1604335:DXZ79_RS01340
uniprot id: A0A386H9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1604335:DXZ79 RS19580
gene id: 1604335:DXZ79_RS19580
uniprot id: A0A386HJ01
names: Similarity
messages: Belongs to the pirin family.

1604335:DXZ79 RS12315
gene id: 1604335:DXZ79_RS12315
uniprot id: A0A386HFB4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1604335:DXZ79 RS03210
gene id: 1604335:DXZ79_RS03210
uniprot id: A0A386HAN7
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1604335:DXZ79 RS02230
gene id: 1604335:DXZ79_RS02230
uniprot id: A0A8D4MZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1604335:DXZ79 RS12245
gene id: 1604335:DXZ79_RS12245
uniprot id: A0A386HFU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1604335:DXZ79 RS00850
gene id: 1604335:DXZ79_RS00850
uniprot id: A0A8E4BM84
names: Similarity
messages: Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.

1604335:DXZ79 RS15015
gene id: 1604335:DXZ79_RS15015
uniprot id: A0A386HGX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1604335:DXZ79 RS09890
gene id: 1604335:DXZ79_RS09890
uniprot id: A0A386HDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS17820
gene id: 1604335:DXZ79_RS17820
uniprot id: A0A386HIM1
names: Similarity
messages: Belongs to the glutamate synthase family.

1604335:DXZ79 RS03375
gene id: 1604335:DXZ79_RS03375
uniprot id: A0A386HAK2
names: Similarity
messages: Belongs to the Smp family.

1604335:DXZ79 RS14790
gene id: 1604335:DXZ79_RS14790
uniprot id: A0A386HG71
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1604335:DXZ79 RS09050
gene id: 1604335:DXZ79_RS09050
uniprot id: A0A386HDQ9
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1604335:DXZ79 RS08680
gene id: 1604335:DXZ79_RS08680
uniprot id: A0A8D4N458
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1604335:DXZ79 RS07220
gene id: 1604335:DXZ79_RS07220
uniprot id: A0A386HCM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1604335:DXZ79 RS17990
gene id: 1604335:DXZ79_RS17990
uniprot id: A0A386HIQ1
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS02165
gene id: 1604335:DXZ79_RS02165
uniprot id: A0A386HAW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1604335:DXZ79 RS01035
gene id: 1604335:DXZ79_RS01035
uniprot id: A0A386H9P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

1604335:DXZ79 RS12045
gene id: 1604335:DXZ79_RS12045
uniprot id: A0A386HFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1604335:DXZ79 RS13640
gene id: 1604335:DXZ79_RS13640
uniprot id: A0A386HFL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1604335:DXZ79 RS00955
gene id: 1604335:DXZ79_RS00955
uniprot id: A0A386HA05
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1604335:DXZ79 RS06440
gene id: 1604335:DXZ79_RS06440
uniprot id: A0A386HC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1604335:DXZ79 RS03405
gene id: 1604335:DXZ79_RS03405
uniprot id: A0A386HB56
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1604335:DXZ79 RS04315
gene id: 1604335:DXZ79_RS04315
uniprot id: A0A386HBF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

1604335:DXZ79 RS09520
gene id: 1604335:DXZ79_RS09520
uniprot id: A0A386HDR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1604335:DXZ79 RS10915
gene id: 1604335:DXZ79_RS10915
uniprot id: A0A386HF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS00500
gene id: 1604335:DXZ79_RS00500
uniprot id: A0A386H9U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1604335:DXZ79 RS03470
gene id: 1604335:DXZ79_RS03470
uniprot id: A0A386HJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1604335:DXZ79 RS04010
gene id: 1604335:DXZ79_RS04010
uniprot id: A0A8D4N3F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1604335:DXZ79 RS05450
gene id: 1604335:DXZ79_RS05450
uniprot id: A0A386HBM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RodZ family.
messages: Cell inner membrane
messages: Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
messages: The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm.

1604335:DXZ79 RS04510
gene id: 1604335:DXZ79_RS04510
uniprot id: A0A386HBW8
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS19770
gene id: 1604335:DXZ79_RS19770
uniprot id: A0A386HJC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1604335:DXZ79 RS10255
gene id: 1604335:DXZ79_RS10255
uniprot id: A0A386HE28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1604335:DXZ79 RS07460
gene id: 1604335:DXZ79_RS07460
uniprot id: A0A386HCS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1604335:DXZ79 RS04615
gene id: 1604335:DXZ79_RS04615
uniprot id: A0A386HBY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1604335:DXZ79 RS19740
gene id: 1604335:DXZ79_RS19740
uniprot id: A0A386HKN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1604335:DXZ79 RS01315
gene id: 1604335:DXZ79_RS01315
uniprot id: A0A386HA88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1604335:DXZ79 RS05610
gene id: 1604335:DXZ79_RS05610
uniprot id: A0A386HBQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

1604335:DXZ79 RS14855
gene id: 1604335:DXZ79_RS14855
uniprot id: A0A386HGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1604335:DXZ79 RS11335
gene id: 1604335:DXZ79_RS11335
uniprot id: A0A386HEM3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1604335:DXZ79 RS03515
gene id: 1604335:DXZ79_RS03515
uniprot id: A0A386HAU3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1604335:DXZ79 RS17030
gene id: 1604335:DXZ79_RS17030
uniprot id: A0A386HHZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1604335:DXZ79 RS02210
gene id: 1604335:DXZ79_RS02210
uniprot id: A0A8D4N1F2
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1604335:DXZ79 RS10270
gene id: 1604335:DXZ79_RS10270
uniprot id: A0A386HE92
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1604335:DXZ79 RS14050
gene id: 1604335:DXZ79_RS14050
uniprot id: A0A386HGC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS13230
gene id: 1604335:DXZ79_RS13230
uniprot id: A0A8D4SSF2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1604335:DXZ79 RS08585
gene id: 1604335:DXZ79_RS08585
uniprot id: A0A386HDT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1604335:DXZ79 RS18370
gene id: 1604335:DXZ79_RS18370
uniprot id: A0A386HIG7
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS19565
gene id: 1604335:DXZ79_RS19565
uniprot id: A0A386HJ29
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1604335:DXZ79 RS02645
gene id: 1604335:DXZ79_RS02645
uniprot id: A0A8D4SQP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1604335:DXZ79 RS00610
gene id: 1604335:DXZ79_RS00610
uniprot id: A0A386HA44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

1604335:DXZ79 RS18905
gene id: 1604335:DXZ79_RS18905
uniprot id: A0A386HJI8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1604335:DXZ79 RS04265
gene id: 1604335:DXZ79_RS04265
uniprot id: A0A386HBI8
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1604335:DXZ79 RS09410
gene id: 1604335:DXZ79_RS09410
uniprot id: A0A386HE52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm

1604335:DXZ79 RS14635
gene id: 1604335:DXZ79_RS14635
uniprot id: A0A386HGW8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1604335:DXZ79 RS05940
gene id: 1604335:DXZ79_RS05940
uniprot id: A0A386HC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1604335:DXZ79 RS16095
gene id: 1604335:DXZ79_RS16095
uniprot id: A0A386HHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1604335:DXZ79 RS09175
gene id: 1604335:DXZ79_RS09175
uniprot id: A0A386HDF7
names: Similarity
messages: Belongs to the PhoH family.

1604335:DXZ79 RS02375
gene id: 1604335:DXZ79_RS02375
uniprot id: A0A8D4SPM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1604335:DXZ79 RS07910
gene id: 1604335:DXZ79_RS07910
uniprot id: A0A386HCZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1604335:DXZ79 RS12190
gene id: 1604335:DXZ79_RS12190
uniprot id: A0A8D4N526
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1604335:DXZ79 RS05255
gene id: 1604335:DXZ79_RS05255
uniprot id: A0A386HCA7
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1604335:DXZ79 RS06400
gene id: 1604335:DXZ79_RS06400
uniprot id: A0A386HCT7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1604335:DXZ79 RS00570
gene id: 1604335:DXZ79_RS00570
uniprot id: A0A8D4N0W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1604335:DXZ79 RS16910
gene id: 1604335:DXZ79_RS16910
uniprot id: A0A386HHX9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1604335:DXZ79 RS07895
gene id: 1604335:DXZ79_RS07895
uniprot id: A0A386HDH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1604335:DXZ79 RS16160
gene id: 1604335:DXZ79_RS16160
uniprot id: A0A386HGZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1604335:DXZ79 RS20335
gene id: 1604335:DXZ79_RS20335
uniprot id: A0A386HK87
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1604335:DXZ79 RS03360
gene id: 1604335:DXZ79_RS03360
uniprot id: A0A8E4BMI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

1604335:DXZ79 RS20525
gene id: 1604335:DXZ79_RS20525
uniprot id: A0A386HJU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1604335:DXZ79 RS14735
gene id: 1604335:DXZ79_RS14735
uniprot id: A0A386HGR8
names: Similarity
messages: Belongs to the P(II) protein family.

1604335:DXZ79 RS05840
gene id: 1604335:DXZ79_RS05840
uniprot id: A0A8D4N3Z5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1604335:DXZ79 RS05985
gene id: 1604335:DXZ79_RS05985
uniprot id: A0A386HC46
names: Subcellular Location Annotation
messages: Cytoplasm

1604335:DXZ79 RS01450
gene id: 1604335:DXZ79_RS01450
uniprot id: A0A8D4N1Q7
names: Similarity
messages: Belongs to the IMPACT family.

1604335:DXZ79 RS01625
gene id: 1604335:DXZ79_RS01625
uniprot id: A0A386H9Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

1604335:DXZ79 RS11800
gene id: 1604335:DXZ79_RS11800
uniprot id: A0A386HFG8
names: Similarity
messages: Belongs to the UPF0053 family.

1604335:DXZ79 RS06935
gene id: 1604335:DXZ79_RS06935
uniprot id: A0A386HD10
names: Subcellular Location Annotation
messages: Membrane

1604335:DXZ79 RS18425
gene id: 1604335:DXZ79_RS18425
uniprot id: A0A386HIH2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1604335:DXZ79 RS18175
gene id: 1604335:DXZ79_RS18175
uniprot id: A0A386HIK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1604335:DXZ79 RS13070
gene id: 1604335:DXZ79_RS13070
uniprot id: A0A386HFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1604335:DXZ79 RS19800
gene id: 1604335:DXZ79_RS19800
uniprot id: A0A386HJL5
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1604335:DXZ79 RS17640
gene id: 1604335:DXZ79_RS17640
uniprot id: A0A386HIJ3
names: Similarity
messages: Belongs to the UxaA family.

1604335:DXZ79 RS13395
gene id: 1604335:DXZ79_RS13395
uniprot id: A0A386HFZ9
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1604335:DXZ79 RS08525
gene id: 1604335:DXZ79_RS08525
uniprot id: A0A386HDQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1604335:DXZ79 RS05960
gene id: 1604335:DXZ79_RS05960
uniprot id: A0A8E3ZHQ8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1604335:DXZ79 RS17180
gene id: 1604335:DXZ79_RS17180
uniprot id: A0A386HI30
names: Similarity
messages: Belongs to the bacterial secretin family.

1604335:DXZ79 RS00510
gene id: 1604335:DXZ79_RS00510
uniprot id: A0A386H9G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1604335:DXZ79 RS05325
gene id: 1604335:DXZ79_RS05325
uniprot id: A0A8D4N343
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1604335:DXZ79 RS15405
gene id: 1604335:DXZ79_RS15405
uniprot id: A0A386HH63
names: Similarity
messages: Belongs to the thioredoxin family.

1604335:DXZ79 RS07850
gene id: 1604335:DXZ79_RS07850
uniprot id: A0A386HDM6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

1604335:DXZ79 RS00070
gene id: 1604335:DXZ79_RS00070
uniprot id: A0A386H9W2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1604335:DXZ79 RS18145
gene id: 1604335:DXZ79_RS18145
uniprot id: A0A386HIM4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.